<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03807440</url>
  </required_header>
  <id_info>
    <org_study_id>1245-0187</org_study_id>
    <nct_id>NCT03807440</nct_id>
  </id_info>
  <brief_title>DIA_CENTRAL:T2D Treatment Pattern in Central Europe</brief_title>
  <official_title>CORDIALLY® - CEE: Characteristics of Patients With Type 2 Diabetes Treated With Modern Antidiabetic Drugs. A Real World Data Collection of Patient Baseline Characteristics, Treatment Patterns and Comorbidities in Central Eastern European (CEE) Countries</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Boehringer Ingelheim</agency>
      <agency_class>Industry</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>Boehringer Ingelheim</source>
  <oversight_info>
    <is_fda_regulated_drug>Yes</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      This is a non-interventional study using existing data including medical chart review.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">August 26, 2019</start_date>
  <completion_date type="Actual">August 31, 2021</completion_date>
  <primary_completion_date type="Actual">August 31, 2021</primary_completion_date>
  <study_type>Observational</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <observational_model>Other</observational_model>
    <time_perspective>Retrospective</time_perspective>
  </study_design_info>
  <primary_outcome>
    <measure>T2D patients' baseline characteristics when initiating either empagliflozin - or other SGLT2i, DPP4i or GLP1a on top of current antidiabetic treatment by different HCP specialties in CEE countries</measure>
    <time_frame>at baseline</time_frame>
  </primary_outcome>
  <secondary_outcome>
    <measure>Burden of comorbidities (prevalence of cardiovascular disease (CVD), chronic kidney disease (CKD) and CVD/CKD risk factors) in this T2D patient population</measure>
    <time_frame>up to 4 months</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Actual treatment use in patients with and without established CVD</measure>
    <time_frame>up to 4 months</time_frame>
    <description>Established CV disease defined as acute myocardial infarction (AMI), cardiology intervention, ischemic heart disease (IHD), congestive heart failure (CHF), peripheral arterial disease (PAD), or stroke</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Association of socioeconomic parameters with treatment decisions</measure>
    <time_frame>up to 4 months</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Discontinuation rate for GLP1a, DPP4i and SGLT2i after a follow up of approximately one year from the initial time point</measure>
    <time_frame>up to 14 months</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Reasons for discontinuation for GLP1a, DPP4i and SGLT2i after a follow up of approximately one year from the initial time point</measure>
    <time_frame>up to 14 months</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Average duration of treatment for GLP1a, DPP4i and SGLT2i after a follow up of approximately one year from the initial time point</measure>
    <time_frame>up to 14 months</time_frame>
  </secondary_outcome>
  <number_of_groups>1</number_of_groups>
  <enrollment type="Actual">3735</enrollment>
  <condition>Diabetes Mellitus, Type 2</condition>
  <arm_group>
    <arm_group_label>Subjects with Diabetes Mellitus, Type 2</arm_group_label>
  </arm_group>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Empagliflozin</intervention_name>
    <description>Empagliflozin</description>
    <arm_group_label>Subjects with Diabetes Mellitus, Type 2</arm_group_label>
    <other_name>Jardiance® Synjardy® Trajenta® Jentadueto®</other_name>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Sodium Glucose Transporter 2 inhibitor</intervention_name>
    <description>Sodium Glucose Transporter 2 inhibitor</description>
    <arm_group_label>Subjects with Diabetes Mellitus, Type 2</arm_group_label>
    <other_name>Jardiance® Synjardy® Trajenta® Jentadueto®</other_name>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Dipeptidyl-peptidase 4 inhibitor</intervention_name>
    <description>Dipeptidyl-peptidase 4 inhibitor</description>
    <arm_group_label>Subjects with Diabetes Mellitus, Type 2</arm_group_label>
    <other_name>Jardiance® Synjardy® Trajenta® Jentadueto®</other_name>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Glucagon-like peptide 1 agonist</intervention_name>
    <description>Glucagon-like peptide 1 agonist</description>
    <arm_group_label>Subjects with Diabetes Mellitus, Type 2</arm_group_label>
    <other_name>Jardiance® Synjardy® Trajenta® Jentadueto®</other_name>
  </intervention>
  <eligibility>
    <study_pop>
      <textblock>
        Adult patients (18 years of age or older) with Type 2 Diabetes diagnosis, naïve to&#xD;
        treatment with empagliflozin or other Sodium Glucose Transporter 2 inhibitor (SGLT2i),&#xD;
        DPP4i (Dipeptidyl-peptidase 4 inhibitor) or GLP1a (Glucagon-like peptide 1 agonist) at&#xD;
        index date were chosen.&#xD;
      </textblock>
    </study_pop>
    <sampling_method>Non-Probability Sample</sampling_method>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          1. Written informed consent prior to participation&#xD;
&#xD;
          2. Female and male patients age ≥ 18 years&#xD;
&#xD;
          3. Patients with T2D diagnosis&#xD;
&#xD;
          4. Patients who have been newly initiated (first ever use) with empagliflozin or other&#xD;
             Sodium Glucose Transporter 2 inhibitor (SGLT2i), Dipeptidyl-peptidase 4 inhibitor&#xD;
             (DPP4i) or Glucagon-like peptide 1 agonist (GLP1a) between September 2018 and December&#xD;
             2018 (study index date 1)&#xD;
&#xD;
          5. Patients have been naïve to treatment with empagliflozin or other Sodium Glucose&#xD;
             Transporter 2 inhibitor (SGLT2i), Dipeptidyl-peptidase 4 inhibitor (DPP4i) or&#xD;
             Glucagon-like peptide 1 agonist (GLP1a) at study index date 1&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          1. Patients age &lt; 18 years&#xD;
&#xD;
          2. Patients with diagnosis of other types of diabetes than T2D&#xD;
&#xD;
          3. Patients who do not provide written consent to the terms of the study&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Alexey Medvedchikov, +43180105-7896</last_name>
    <role>Study Chair</role>
    <affiliation>Alexey.Medvedchikov@Boehringer-Ingelheim.com</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>MHAT &quot;Julia Verevska-Byala&quot; EOOD, Center Nr.: 35903</name>
      <address>
        <city>Byala</city>
        <zip>7100</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC &quot;Diamedical 2013&quot; OOD, Center Nr.: 35902</name>
      <address>
        <city>Dimitrovgrad</city>
        <zip>6400</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MBAL- Dobrich AD, Center Nr.: 35916</name>
      <address>
        <city>Dobrich</city>
        <zip>9300</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. T. K. Bacheva - ASMP-IP-E EOOD, Center Nr.: 35904</name>
      <address>
        <city>Dupnitsa</city>
        <zip>2600</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MHAT &quot;Medline Clinic&quot;, Center Nr.: 35911</name>
      <address>
        <city>Plovdiv</city>
        <zip>4000</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC Kuchuk Parij OOD, Center Nr.: 35906</name>
      <address>
        <city>Plovdiv</city>
        <zip>4030</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC Saint Elisaveta-Rakovski EOOD, Center Nr.: 35909</name>
      <address>
        <city>Rakovski</city>
        <zip>4150</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>&quot;Medical Center-Razgrad&quot;OOD, Center Nr.: 35910</name>
      <address>
        <city>Razgrad</city>
        <zip>7200</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>DCC 1 - Russe EOOD, Center Nr.: 35905</name>
      <address>
        <city>Russe</city>
        <zip>7000</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MBAL &quot;Hadzhi Dimitar&quot; OOD, Center Nr.: 35915</name>
      <address>
        <city>Sliven</city>
        <zip>8800</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC Polimed AD, Center Nr.: 35907</name>
      <address>
        <city>Sofia</city>
        <zip>1303</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC Gina - LZ SIMP EOOD, Center Nr.: 35918</name>
      <address>
        <city>Sofia</city>
        <zip>1463</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC &quot;Vitaclinic&quot; EOOD, Center Nr.: 35901</name>
      <address>
        <city>Sofia</city>
        <zip>1680</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MC Kalimat EOOD, Center Nr.: 35914</name>
      <address>
        <city>Sofia</city>
        <zip>1680</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Acibadem City Clinic Medical Center Varna EOOD, Center Nr.: 35908</name>
      <address>
        <city>Varna</city>
        <zip>9002</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Michal Brada, Center Nr.: 42001</name>
      <address>
        <city>Beclav</city>
        <zip>69002</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. Kovaová, Center Nr.: 42069</name>
      <address>
        <city>Beroun</city>
        <zip>26656</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Alice Sýkorová, Center Nr.: 42057</name>
      <address>
        <city>Bilina</city>
        <zip>418 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr. Alica Vesela, Center Nr.: 42030</name>
      <address>
        <city>Broumov</city>
        <zip>55001</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>EUC Klinika eské Budjovice, Center Nr.: 42052</name>
      <address>
        <city>Eské Budjovice</city>
        <zip>37001</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Lékaský dm Géko, Center Nr.: 42059</name>
      <address>
        <city>Eské Budjovice</city>
        <zip>37011</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Barbara Buzová, Center Nr.: 42003</name>
      <address>
        <city>Havíov</city>
        <zip>73601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Zaviatiová, Petra, Center Nr.: 42004</name>
      <address>
        <city>Havíov</city>
        <zip>73601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Radana Syslová, Center Nr.: 42035</name>
      <address>
        <city>Hlušovice</city>
        <zip>78314</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pavel Kasík, Center Nr.: 42046</name>
      <address>
        <city>Hoovice</city>
        <zip>268 31</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Petr Maule, Center Nr.: 42054</name>
      <address>
        <city>Humpolec</city>
        <zip>39601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Mediab Jihlava s.r.o., Center Nr.: 42066</name>
      <address>
        <city>Jihlava</city>
        <zip>58601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice MUDr. Gita Markofová, Center Nr.: 42053</name>
      <address>
        <city>Karlovy Vary</city>
        <zip>36066</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. Konená, Center Nr.: 42036</name>
      <address>
        <city>Karviná - Staré Msto</city>
        <zip>73301</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Zdzislaw Wranka, Center Nr.: 42072</name>
      <address>
        <city>Karviná-Hranice</city>
        <zip>73301</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pavel Tománek, Center Nr.: 42028</name>
      <address>
        <city>Kopivnice</city>
        <zip>74221</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>DIABET HELP s.r.o., Center Nr.: 42058</name>
      <address>
        <city>Kralupy nad Vltavou</city>
        <zip>27801</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr.Tomáš Edelsberger, Center Nr.: 42007</name>
      <address>
        <city>Krnov</city>
        <zip>79401</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Jitka Hasalová, Center Nr.: 42010</name>
      <address>
        <city>Kromiz</city>
        <zip>76901</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>árka Drinková, Center Nr.: 42038</name>
      <address>
        <city>Lede Nad Sázavou</city>
        <zip>58401</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Martina Košková, Center Nr.: 42047</name>
      <address>
        <city>Mladá Boleslav</city>
        <zip>29350</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dobromila Vykoupilová, Center Nr.: 42033</name>
      <address>
        <city>Nmice Nad Hanou</city>
        <zip>79827</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Karel Churavý, Center Nr.: 42005</name>
      <address>
        <city>Nový Jiín</city>
        <zip>74101</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>árka Kubánková, Center Nr.: 42048</name>
      <address>
        <city>Nymburk</city>
        <zip>28802</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Agentura Science Pro spol. s.r.o., Center Nr.: 42002</name>
      <address>
        <city>Olomouc</city>
        <zip>772 00</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Anna Rancová, Center Nr.: 42025</name>
      <address>
        <city>Olomouc</city>
        <zip>77900</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Josef íný, Center Nr.: 42026</name>
      <address>
        <city>Opava</city>
        <zip>74601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr.Tomáš Hrdina, Center Nr.: 42015</name>
      <address>
        <city>Opono</city>
        <zip>51773</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Radka Nágelová, Center Nr.: 42020</name>
      <address>
        <city>Ostrava Poruba</city>
        <zip>70800</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. Šeptáková, Center Nr.: 42074</name>
      <address>
        <city>Ostrava</city>
        <zip>700 30</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. René Turínek, Center Nr.: 42034</name>
      <address>
        <city>Ostrava</city>
        <zip>70200</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr. Eva Raická, Center Nr.: 42024</name>
      <address>
        <city>Ostrava</city>
        <zip>71000</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Jitka Homolová, Center Nr.: 42012</name>
      <address>
        <city>Ostrava</city>
        <zip>72880</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>AIDIN VK s.r.o., Center Nr.: 42017</name>
      <address>
        <city>Perov</city>
        <zip>75301</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Zdenk Jankovec, Center Nr.: 42044</name>
      <address>
        <city>Plze</city>
        <zip>30100</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Diabetologická a interní ambulance, Center Nr.: 42064</name>
      <address>
        <city>Podbrady</city>
        <zip>29001</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Milena Peterková, Center Nr.: 42063</name>
      <address>
        <city>Praha 2</city>
        <zip>12143</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr.Michala Pelikánová s.r.o., Center Nr.: 42055</name>
      <address>
        <city>Praha 4</city>
        <zip>14000</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Markéta Hovorková, Center Nr.: 42042</name>
      <address>
        <city>Praha 4</city>
        <zip>14021</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Jakub Hron, Center Nr.: 42043</name>
      <address>
        <city>Praha 4</city>
        <zip>14300</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Milan Fleka, Center Nr.: 42041</name>
      <address>
        <city>Praha 5</city>
        <zip>15000</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Jií Jón, Center Nr.: 42045</name>
      <address>
        <city>Praha 5</city>
        <zip>15030</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Lucie Kufová, Center Nr.: 42062</name>
      <address>
        <city>Praha 5</city>
        <zip>15030</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Ida Reissová, Center Nr.: 42056</name>
      <address>
        <city>Praha 6</city>
        <zip>16300</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Barbora Diepoltová, Center Nr.: 42037</name>
      <address>
        <city>Praha 9</city>
        <zip>19014</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr. Jana Houdová, Center Nr.: 42068</name>
      <address>
        <city>Praha</city>
        <zip>10000</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MUDr. Vra Prýmková, Center Nr.: 42070</name>
      <address>
        <city>Píbram</city>
        <zip>26101</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Petronela Janeková, Center Nr.: 42065</name>
      <address>
        <city>Rumburk</city>
        <zip>40801</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Miroslav Lindovský, Center Nr.: 42051</name>
      <address>
        <city>Sokolov</city>
        <zip>35601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dana Fialkoviová, Center Nr.: 42040</name>
      <address>
        <city>Strakonice</city>
        <zip>38601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Marek Frydrych, Center Nr.: 42008</name>
      <address>
        <city>Tebí</city>
        <zip>674 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Marek Frydrych, Center Nr.: 42077</name>
      <address>
        <city>Tebí</city>
        <zip>674 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Diabetologická ambulance s.r.o., Center Nr.: 42076</name>
      <address>
        <city>Uherské Hradišt</city>
        <zip>68601</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. Hrmová, Center Nr.: 42073</name>
      <address>
        <city>Vlašim</city>
        <zip>25801</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Lubomír Kudlej, Center Nr.: 42050</name>
      <address>
        <city>Vrchlabí</city>
        <zip>54301</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>AdiaMed s.r.o., Center Nr.: 42009</name>
      <address>
        <city>Vsetín</city>
        <zip>75501</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>EUC Klinika Zlín a.s., Center Nr.: 42075</name>
      <address>
        <city>Zlín</city>
        <zip>76001</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Robin Urbánek, Center Nr.: 42029</name>
      <address>
        <city>Zlín</city>
        <zip>76001</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Bajcsy-Zsilinszky Kórház és Rendelintézet, Center Nr.: 36019</name>
      <address>
        <city>Budapest</city>
        <zip>1106</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Jahn Ferenc Dél-pesti Kórház és Rendelintézet, Center Nr.: 36014</name>
      <address>
        <city>Budapest</city>
        <zip>1204</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Debreceni Egyetem Klinikai Központ, Kardiológiai Klinika, Center Nr.: 36006</name>
      <address>
        <city>Debrecen</city>
        <zip>4032</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Kátai Gábor Kórház, Diabetológia Szakrendelés, Center Nr.: 36007</name>
      <address>
        <city>Karcag</city>
        <zip>5300</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Practice Dr. Lelkesi Anita, Center Nr.: 36013</name>
      <address>
        <city>Mátészalka</city>
        <zip>4700</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Nagyatádi Kórház, Center Nr.: 36021</name>
      <address>
        <city>Nagyatád</city>
        <zip>7500</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Nyírségi Diabetes Centrum, Center Nr.: 36024</name>
      <address>
        <city>Nyíregyháza</city>
        <zip>4400</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. Wagner Zoltán, Center Nr.: 36020</name>
      <address>
        <city>Pécs</city>
        <zip>7625</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Siófoki Kórház Rendelintézet, Center Nr.: 36004</name>
      <address>
        <city>Siófok</city>
        <zip>8600</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Soproni Gyógyközpont, Center Nr.: 36018</name>
      <address>
        <city>Sopron</city>
        <zip>9400</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Gabinet Diabetologiczno- Internistyczny Katarzyna Wasilewska, Center Nr.: 48011</name>
      <address>
        <city>Biaystok</city>
        <zip>15-591</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>NZOZ DIAMED Sp. z o.o., Center Nr.: 48061</name>
      <address>
        <city>Czechowice-Dziedzice</city>
        <zip>43-502</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Prywatny Gabinet Lekarski dr n. med. Joanna Sawer-Szewczyk, Center Nr.: 48055</name>
      <address>
        <city>Czyca</city>
        <zip>99-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Zespó Opieki Zdrowotnej w czycy, Center Nr.: 48054</name>
      <address>
        <city>Czyca</city>
        <zip>99-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>NZOZ Sal Med, Center Nr.: 48047</name>
      <address>
        <city>Dzieroniów</city>
        <zip>58-200</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Poradnia Diabetologiczna, Center Nr.: 48028</name>
      <address>
        <city>Gorlice</city>
        <zip>38-300</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Indywidualna Specjalistyczna Praktyka Lekarska Piotr Piskozub Specjalista Diabetolog, Center Nr.: 48042</name>
      <address>
        <city>Jelenia Góra</city>
        <zip>58-506</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>NZOZ Poradnia Diabetologiczna, Center Nr.: 48038</name>
      <address>
        <city>Konin</city>
        <zip>62-504</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Zakad Opieki Medycznej Sanatio; Sp. Z. o.o., Center Nr.: 48030</name>
      <address>
        <city>Kraków</city>
        <zip>31-548</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Prywatny Gabinet Lekarski Tomasz Wierzykowski, Center Nr.: 48053</name>
      <address>
        <city>Kutno</city>
        <zip>99-300</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Indywidualna Specjalistyczna Praktyka Lekarska Magorzata Poskoska-Lemaska, Center Nr.: 48035</name>
      <address>
        <city>Kwidzyn</city>
        <zip>82-500</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Indywidualna Specjalistyczna Praktyka Lekarska Barbara Soróbka, Center Nr.: 48001</name>
      <address>
        <city>Legnica</city>
        <zip>59-220</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Poradnia Cukrzycowa SP ZOZ w Lesku, Center Nr.: 48024</name>
      <address>
        <city>Lesko</city>
        <zip>38-600</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Lumed Sp. z o.o., Center Nr.: 48032</name>
      <address>
        <city>Lubaczów</city>
        <zip>37-600</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>DIABETA-CARE Sp.z o.o., Center Nr.: 48008</name>
      <address>
        <city>Lubin</city>
        <zip>59-300</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Poradnia Diabetologiczna Dr. mudziska, Center Nr.: 48013</name>
      <address>
        <city>Nako Nad Noteci</city>
        <zip>89-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Alfa Specjalistyczne Gabinety Lekarskie Ewa Moroz, Center Nr.: 48007</name>
      <address>
        <city>Nowy Scz</city>
        <zip>33-300</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Poradnia Diabetologiczna Dr. Adamczyk-Gajda, Center Nr.: 48031</name>
      <address>
        <city>Olenica</city>
        <zip>56-400</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>MED-ART Sp. z o.o., Center Nr.: 48052</name>
      <address>
        <city>Orzesze</city>
        <zip>43-180</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Indywidualna Specjalistyczna Praktyka Lekarska Wiesawa Fischer, Center Nr.: 48020</name>
      <address>
        <city>Ostrów Wielkopolski</city>
        <zip>63-400</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Prywatny Gabinet Lekarski azuka, Center Nr.: 48026</name>
      <address>
        <city>Parczew</city>
        <zip>21-200</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Powiatowy Szpital Specjalistyczny w Stalowej Woli, Center Nr.: 48056</name>
      <address>
        <city>Stalowa Wola</city>
        <zip>37-450</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Prywatny Gabinet Lekarski dr n. med. Piotr Gryglas, Center Nr.: 48059</name>
      <address>
        <city>Warszawa</city>
        <zip>03-922</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Poradnia Diabetologiczna Szpitala Powiatowego w Wicborku, Center Nr.: 48003</name>
      <address>
        <city>Wicbork</city>
        <zip>89-410</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Orodek Praktyka Lekarska Konrad Strzelczyk, Center Nr.: 48012</name>
      <address>
        <city>Woomin</city>
        <zip>05-200</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Poradnia Diabetologiczna SPZZOZ w Wyszkowie, Center Nr.: 48067</name>
      <address>
        <city>Wyszków</city>
        <zip>07-200</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Wojewódzka Poradnia dla Chorych na Cukrzyc, Center Nr.: 48025</name>
      <address>
        <city>Zabrze</city>
        <zip>41-800</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Cardiomed, Center Nr.: 48019</name>
      <address>
        <city>Zielona Góra</city>
        <zip>65-001</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Anturium, Center Nr.: 70036</name>
      <address>
        <city>Barnaul</city>
        <zip>656043</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Central city hospital, Center Nr.: 70073</name>
      <address>
        <city>Batajsk</city>
        <zip>346880</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Chelyabinsk regional clinical hospital, Center Nr.: 70069</name>
      <address>
        <city>Chelyabinsk</city>
        <zip>454076</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Limited Liability Company &quot;Uralsky Medical Center&quot;, Center Nr.: 70063</name>
      <address>
        <city>Ekaterinburg</city>
        <zip>620102</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Scientific and Practical Center of Specialized Types of Medical Care &quot;Uralskij Institute of Cardiology&quot;, Center Nr.: 70079</name>
      <address>
        <city>Ekaterinburg</city>
        <zip>620144</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Russian Medical Academy of Continuing Professional Education, Center Nr.: 70058</name>
      <address>
        <city>Irkutsk</city>
        <zip>664049</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>The First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic, Center Nr.: 70037</name>
      <address>
        <city>Izhevsk</city>
        <zip>426039</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Central City Hospital No. 18, Center Nr.: 70051</name>
      <address>
        <city>Kazan</city>
        <zip>420073</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Kemerovo regional clinical hospital named S.V. Belyaev, Center Nr.: 70008</name>
      <address>
        <city>Kemerovo</city>
        <zip>50066</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Polyclinic No. 16, Center Nr.: 70067</name>
      <address>
        <city>Khabarovsk</city>
        <zip>680045</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Kirov Clinical Hospital No. 7 named after V.I. Yurlova, Center Nr.: 70089</name>
      <address>
        <city>Kirov</city>
        <zip>610020</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Krai clinical hospital Nr. 1 named after prof. S.V. Ochapovskogo, Center Nr.: 70049</name>
      <address>
        <city>Krasnodar</city>
        <zip>350086</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Lipetsk Regional Hospital, Center Nr.: 70046</name>
      <address>
        <city>Lipetsk</city>
        <zip>398902</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>SBIH Center for Speech Pathology and Neurorehabilitation MDH, Center Nr.: 70080</name>
      <address>
        <city>Moscow</city>
        <zip>109240</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Clinical Hospital No. 85 of trhe Federal Biomedical Agency, Center Nr.: 70042</name>
      <address>
        <city>Moscow</city>
        <zip>115409</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Polyclinic No. 22 of the Department of Healthcare of the Moscow City, Center Nr.: 70043</name>
      <address>
        <city>Moscow</city>
        <zip>117218</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Polyclinic No. 22 of the Department of Healthcare of the Moscow City, Center Nr.: 70045</name>
      <address>
        <city>Moscow</city>
        <zip>117218</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Polyclinic No 107 of the Moscow City Healthcare Department, Center Nr.: 70082</name>
      <address>
        <city>Moscow</city>
        <zip>127273</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>National Medical Research Center for Endocrinology, Center Nr.: 70025</name>
      <address>
        <city>Moskau</city>
        <zip>117036</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Endocrinology Dispensary of the Moscow City Healthcare Department, Center Nr.: 70032</name>
      <address>
        <city>Moskau</city>
        <zip>119034</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Endocrinology Dispensary of the Moscow City Healthcare Department, Center Nr.: 70041</name>
      <address>
        <city>Moskau</city>
        <zip>119034</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Endocrinology Dispensary of the Moscow City Healthcare Department, Center Nr.: 70081</name>
      <address>
        <city>Moskau</city>
        <zip>119034</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Endocrinology Dispensary of the Moscow City Healthcare Department, Center Nr.: 70084</name>
      <address>
        <city>Moskau</city>
        <zip>119034</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Vessel Clinic, Center Nr.: 70011</name>
      <address>
        <city>Moskau</city>
        <zip>125252</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Clinical Hospital named after V.V. Veresaeva of the Moscow Department of Health, Center Nr.: 70003</name>
      <address>
        <city>Moskau</city>
        <zip>127644</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Polyclinic No. 1, Center Nr.: 70074</name>
      <address>
        <city>Nalchik</city>
        <zip>360051</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City clinical hospital #12 of Sormovskiy district of Nizhniy Novgorod, Center Nr.: 70018</name>
      <address>
        <city>Nizhniy Novgorod</city>
        <zip>603003</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Privolzhsky Research Medical University, Center Nr.: 70085</name>
      <address>
        <city>Nizhny Novgorod</city>
        <zip>603005</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Novokuznetsk City Clinical Hospital No. 1, Center Nr.: 70050</name>
      <address>
        <city>Novokuznetsk</city>
        <zip>654027</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>AVICENNA, Center Nr.: 70065</name>
      <address>
        <city>Novosibirsk</city>
        <zip>630007</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Clinical Polyclinic #16, Center Nr.: 70056</name>
      <address>
        <city>Novosibirsk</city>
        <zip>630078</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Novosibirsk State Medical University, Center Nr.: 70059</name>
      <address>
        <city>Novosibirsk</city>
        <zip>6300911</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>AVICENNA, Center Nr.: 70064</name>
      <address>
        <city>Novosibirsk</city>
        <zip>630099</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Penza regional clinical hospital named after N.N. Burdenko, Center Nr.: 70095</name>
      <address>
        <city>Penza</city>
        <zip>440026</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Private Clinic Salon Roden, Center Nr.: 70086</name>
      <address>
        <city>Perm</city>
        <zip>614000</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City clinical hospital 5, Center Nr.: 70057</name>
      <address>
        <city>Perm</city>
        <zip>614010</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City clinical hospital 5, Center Nr.: 70070</name>
      <address>
        <city>Perm</city>
        <zip>614010</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City polyclinic #16 of the City Rostov-on-Don, Center Nr.: 70027</name>
      <address>
        <city>Rostov-on-Don</city>
        <zip>344092</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>North-West State Medical University named after II. Mechnikov, Center Nr.: 70053</name>
      <address>
        <city>Saint Petersbug</city>
        <zip>191015</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>North-West State Medical University named after II. Mechnikov, Center Nr.: 70077</name>
      <address>
        <city>Saint Petersbug</city>
        <zip>191015</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Medilux-TM, Center Nr.: 70005</name>
      <address>
        <city>Saint Petersburg</city>
        <zip>197227</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Pokrovskaya Hospital, Center Nr.: 70022</name>
      <address>
        <city>Saint Petersburg</city>
        <zip>199106</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>First Saint-Petersburg state medical university named after acad. I.P.Pavlov, Center Nr.: 70024</name>
      <address>
        <city>Saint-Petersburg</city>
        <zip>197022</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>First Saint-Petersburg state medical university named after acad. I.P.Pavlov, Center Nr.: 70087</name>
      <address>
        <city>Saint-Petersburg</city>
        <zip>197022</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Samara city polyclinic Nr. 9 of Oktyabrskiy district, Center Nr.: 70028</name>
      <address>
        <city>Samara</city>
        <zip>443110</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Samara city consulting and diagnostic polyclinic nr. 14, Center Nr.: 70029</name>
      <address>
        <city>Samara</city>
        <zip>443111</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Clinical Hospital of the Saratov city, Center Nr.: 70090</name>
      <address>
        <city>Saratov</city>
        <zip>410004</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>LLC clinic &quot;Family Doctor&quot;, Center Nr.: 70093</name>
      <address>
        <city>Saratov</city>
        <zip>410012</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Multifunctional Medical Clinic &quot;Sova&quot;, Center Nr.: 70030</name>
      <address>
        <city>Saratov</city>
        <zip>410056</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>V.A. Almazov National Medical Research Center, Center Nr.: 70071</name>
      <address>
        <city>St. Petersburg</city>
        <zip>197341</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>AntMed, Center Nr.: 70034</name>
      <address>
        <city>St. Petersburg</city>
        <zip>197349</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Dr. Tsiberkin, Center Nr.: 70048</name>
      <address>
        <city>St. Petersburg</city>
        <zip>197349</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Zabotlivyi Doktor, Center Nr.: 70016</name>
      <address>
        <city>St. Petersburg</city>
        <zip>966550</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Regional Endocrinological Dispensary, Center Nr.: 70078</name>
      <address>
        <city>Stavropol</city>
        <zip>355045</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Tyumen State Medical University, Center Nr.: 70066</name>
      <address>
        <city>Tyumen</city>
        <zip>625023</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City clinical hospital, Center Nr.: 70019</name>
      <address>
        <city>Ufa</city>
        <zip>450014</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>City Polyclinic No.2, Center Nr.: 70062</name>
      <address>
        <city>Ulan-Ude</city>
        <zip>670031</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Limited Liability Company &quot;CENTER&quot;, Center Nr.: 70060</name>
      <address>
        <city>Vladivostok</city>
        <zip>690017</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Regional Clinical Hospital No. 2, Center Nr.: 70092</name>
      <address>
        <city>Vladivostok</city>
        <zip>690035</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Regional Clinical Hospital No. 2, Center Nr.: 70068</name>
      <address>
        <city>Vladivostok</city>
        <zip>690105</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Volgograd Regional Clinical Hospital No. 3, Center Nr.: 70076</name>
      <address>
        <city>Volgograd</city>
        <zip>400001</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Clinical Polyclinic No.28, Center Nr.: 70040</name>
      <address>
        <city>Volgograd</city>
        <zip>400117</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Voronezh City Clinical Hospital #11, Center Nr.: 70035</name>
      <address>
        <city>Voronezh</city>
        <zip>394042</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>State budgetary institution &quot;City polyclinic Nr. 4&quot;, Center Nr.: 70017</name>
      <address>
        <city>Voronezh</city>
        <zip>394077</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>State budgetary institution &quot;City polyclinic Nr. 4&quot;, Center Nr.: 70033</name>
      <address>
        <city>Voronezh</city>
        <zip>394077</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>State budgetary institution &quot;City polyclinic Nr. 4&quot;, Center Nr.: 70055</name>
      <address>
        <city>Voronezh</city>
        <zip>394077</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Bulgaria</country>
    <country>Czechia</country>
    <country>Hungary</country>
    <country>Poland</country>
    <country>Russian Federation</country>
  </location_countries>
  <link>
    <url>http://www.mystudywindow.com</url>
    <description>Related Info</description>
  </link>
  <verification_date>February 2022</verification_date>
  <study_first_submitted>January 15, 2019</study_first_submitted>
  <study_first_submitted_qc>January 15, 2019</study_first_submitted_qc>
  <study_first_posted type="Actual">January 17, 2019</study_first_posted>
  <last_update_submitted>February 18, 2022</last_update_submitted>
  <last_update_submitted_qc>February 18, 2022</last_update_submitted_qc>
  <last_update_posted type="Actual">February 21, 2022</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Diabetes Mellitus, Type 2</mesh_term>
  </condition_browse>
  <intervention_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Empagliflozin</mesh_term>
    <mesh_term>Sodium-Glucose Transporter 2 Inhibitors</mesh_term>
    <mesh_term>Linagliptin</mesh_term>
    <mesh_term>Metformin</mesh_term>
    <mesh_term>Dipeptidyl-Peptidase IV Inhibitors</mesh_term>
    <mesh_term>Glucagon</mesh_term>
    <mesh_term>Glucagon-Like Peptide 1</mesh_term>
  </intervention_browse>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
    <ipd_description>Clinical studies sponsored by Boehringer Ingelheim, phases I to IV, interventional and non-interventional, are in scope for sharing of the raw clinical study data and clinical study documents. Exceptions might apply, e.g. studies in products where Boehringer Ingelheim is not the license holder; studies regarding pharmaceutical formulations and associated analytical methods, and studies pertinent to pharmacokinetics using human biomaterials; studies conducted in a single center or targeting rare diseases (in case of low number of patients and therefore limitations with anonymization).&#xD;
For more details refer to: https://www.mystudywindow.com/msw/datatransparency</ipd_description>
  </patient_data>
  <pending_results>
    <submitted>May 2, 2022</submitted>
    <returned>February 1, 2023</returned>
    <submitted>February 23, 2023</submitted>
  </pending_results>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03807440
org study id: 1245-0187
nct id: NCT03807440
lead sponsor: 
is fda regulated drug: Yes
is fda regulated device: No
This is a non-interventional study using existing data including medical chart review.
observational model: Other
time perspective: Retrospective
measure: T2D patients' baseline characteristics when initiating either empagliflozin - or other SGLT2i, DPP4i or GLP1a on top of current antidiabetic treatment by different HCP specialties in CEE countries
time frame: at baseline
measure: Burden of comorbidities (prevalence of cardiovascular disease (CVD), chronic kidney disease (CKD) and CVD/CKD risk factors) in this T2D patient population
time frame: up to 4 months
measure: Actual treatment use in patients with and without established CVD
time frame: up to 4 months
description: Established CV disease defined as acute myocardial infarction (AMI), cardiology intervention, ischemic heart disease (IHD), congestive heart failure (CHF), peripheral arterial disease (PAD), or stroke
measure: Association of socioeconomic parameters with treatment decisions
time frame: up to 4 months
measure: Discontinuation rate for GLP1a, DPP4i and SGLT2i after a follow up of approximately one year from the initial time point
time frame: up to 14 months
measure: Reasons for discontinuation for GLP1a, DPP4i and SGLT2i after a follow up of approximately one year from the initial time point
time frame: up to 14 months
measure: Average duration of treatment for GLP1a, DPP4i and SGLT2i after a follow up of approximately one year from the initial time point
time frame: up to 14 months
arm group label: Subjects with Diabetes Mellitus, Type 2
intervention type: Drug
intervention name: Empagliflozin
description: Empagliflozin
arm group label: Subjects with Diabetes Mellitus, Type 2
other name: Jardiance® Synjardy® Trajenta® Jentadueto®
intervention type: Drug
intervention name: Sodium Glucose Transporter 2 inhibitor
description: Sodium Glucose Transporter 2 inhibitor
arm group label: Subjects with Diabetes Mellitus, Type 2
other name: Jardiance® Synjardy® Trajenta® Jentadueto®
intervention type: Drug
intervention name: Dipeptidyl-peptidase 4 inhibitor
description: Dipeptidyl-peptidase 4 inhibitor
arm group label: Subjects with Diabetes Mellitus, Type 2
other name: Jardiance® Synjardy® Trajenta® Jentadueto®
intervention type: Drug
intervention name: Glucagon-like peptide 1 agonist
description: Glucagon-like peptide 1 agonist
arm group label: Subjects with Diabetes Mellitus, Type 2
other name: Jardiance® Synjardy® Trajenta® Jentadueto®
study pop: 
sampling method: Non-Probability Sample
criteria: 
gender: All
minimum age: 18 Years
maximum age: N/A
healthy volunteers: No
last name: Alexey Medvedchikov, +43180105-7896
role: Study Chair
affiliation: Alexey.Medvedchikov@Boehringer-Ingelheim.com
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country: Bulgaria
country: Czechia
country: Hungary
country: Poland
country: Russian Federation
url: http://www.mystudywindow.com
description: Related Info
responsible party type: Sponsor
mesh term: Diabetes Mellitus, Type 2
mesh term: Empagliflozin
mesh term: Sodium-Glucose Transporter 2 Inhibitors
mesh term: Linagliptin
mesh term: Metformin
mesh term: Dipeptidyl-Peptidase IV Inhibitors
mesh term: Glucagon
mesh term: Glucagon-Like Peptide 1
sharing ipd: No
ipd description: Clinical studies sponsored by Boehringer Ingelheim, phases I to IV, interventional and non-interventional, are in scope for sharing of the raw clinical study data and clinical study documents. Exceptions might apply, e.g. studies in products where Boehringer Ingelheim is not the license holder; studies regarding pharmaceutical formulations and associated analytical methods, and studies pertinent to pharmacokinetics using human biomaterials; studies conducted in a single center or targeting rare diseases (in case of low number of patients and therefore limitations with anonymization).
For more details refer to: https://www.mystudywindow.com/msw/datatransparency
submitted: May 2, 2022
returned: February 1, 2023
submitted: February 23, 2023