<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03807401</url>
  </required_header>
  <id_info>
    <org_study_id>69HCL18_0721</org_study_id>
    <secondary_id>2018-A03175-50</secondary_id>
    <nct_id>NCT03807401</nct_id>
  </id_info>
  <brief_title>A Technical Innovation of Prismatic Adaptation Test in Healthy Subject, in Favour of Autonomy and Independence in Daily Life Following a Brain Injury</brief_title>
  <acronym>PRIS'TUEL</acronym>
  <official_title>To Simulate Prismatic Adaptation in Healthy Subject : a Technical Innovation in Favour of Autonomy and Independence in Daily Life Following a Brain Injury</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Hospices Civils de Lyon</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>Hospices Civils de Lyon</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      Unilateral neglect is a neuropsychological disorder reflected by a disturbance in the spatial&#xD;
      exploration and distribution of directed attention affecting the contralateral part of space&#xD;
      and body relatively to the brain lesion. The chronic aspect of this pathology leads to a poor&#xD;
      progression following rehabilitation and a decreased independence of patients in daily life.&#xD;
      Thus, it is necessary to set up efficient and long lasting therapies for unilateral neglect&#xD;
      patients to improve their daily quality of life. Prismatic adaptation is now a classical&#xD;
      method which allows patients to improve their neglect through corrective pointing movements&#xD;
      in response to a lateral displacement of the visual field. A large and growing body of&#xD;
      literature has investigated prismatic adaptation as a very promising rehabilitation method,&#xD;
      improving both visuomotor and cognitive features of unilateral neglect. However, its effects&#xD;
      are somehow irregular and clinical applications of this method are still limited. The&#xD;
      necessity for patients to come to the hospital to take advantage of prismatic adaption&#xD;
      sessions draws some limitations about our knowledge concerning 1) the temporal dynamic of&#xD;
      prism adaptation effects on a long-term basis and 2) the optimal duration of treatment (most&#xD;
      of the time constrained by the hospitalization duration) and its therapeutical effects on a&#xD;
      very long-term basis. Moreover, a large number of patients also suffer from motor deficits&#xD;
      which reduce the possibility to optimize the prismatic adaptation session.&#xD;
&#xD;
      Thus, the aim of this project is to develop and validate others modalities of prismatic&#xD;
      adaptation which can be applied at home and for a longer duration. These modalities should&#xD;
      allow the investigator to get insights about the temporal dynamic of prismatic adaptation on&#xD;
      the cognitive system. First, the investigator will investigate the effects of a prismatic&#xD;
      adaptation modality using virtual reality to reproduce the lateral displacement induced by&#xD;
      the prismatic goggles. He will also investigate prismatic adaptation induced by motor&#xD;
      imagery, i.e. with mental representations of pointing movements without concomitant motor&#xD;
      execution. This project could enhance the fundamental knowledge and enable to design new&#xD;
      modalities of therapeutical use of prismatic adaptation (virtual or imaged) so as to allow a&#xD;
      home-based treatment and follow-up. Thus, the aim of this project is to demonstrate the&#xD;
      implication of similar mechanisms through different modalities (virtual and imaged compared&#xD;
      to classical application) and the feasibility of these new modalities of healthy subjects.&#xD;
      Thereafter, the aim will be to use knowledge acquired during this project to set up clinical&#xD;
      trials to test for the efficiency of these modalities on a long-term basis in a pathological&#xD;
      population.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Recruiting</overall_status>
  <start_date type="Actual">October 8, 2019</start_date>
  <completion_date type="Anticipated">April 8, 2024</completion_date>
  <primary_completion_date type="Anticipated">April 8, 2024</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Factorial Assignment</intervention_model>
    <primary_purpose>Basic Science</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Line bisection test, the reference point is the middle of the line.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Line bisection test, the reference point is the middle of the line.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Line bisection test, the reference point is the middle of the line.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Line bisection test, the reference point is the middle of the line.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Goal-directed pointing test, the reference point is the target.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Goal-directed pointing test, the reference point is the target.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Goal-directed pointing test, the reference point is the target.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Goal-directed pointing test, the reference point is the target.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.&#xD;
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right before adaption</time_frame>
    <description>Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Visuospatial performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sensorimotor performances : measure of deviations in mm</measure>
    <time_frame>Day 0 - right after adaption</time_frame>
    <description>Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.</description>
  </primary_outcome>
  <number_of_arms>3</number_of_arms>
  <enrollment type="Anticipated">480</enrollment>
  <condition>Healthy Volunteers</condition>
  <arm_group>
    <arm_group_label>Classical prismatic adaptation</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>Classical prismatic adaptation arm will be divided into two subgroups corresponding to the side of the prismatic displacement (right or left)</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Virtual prismatic adaptation</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>virtual prismatic adaptation arm will be divided into two subgroups corresponding to the side of the prismatic displacement (right or left)</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Imaged prismatic adaptation</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Imaged prismatic adaptation arm will be divided into two subgroups corresponding to the side of the prismatic displacement (right or left)</description>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Prismatic goggles</intervention_name>
    <description>Goggles inducing a lateral displacement of the virtual field of ten degrees. Participants will be asked to wear those goggles during adaptation session and to perform pointing movement toward visual target.</description>
    <arm_group_label>Classical prismatic adaptation</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Virtual reality device</intervention_name>
    <description>The lateral displacement will be simulated thanks to a virtual reality environment. Participants will wear an Oculus Rift instead of the prismatic goggles and will perform pointing movement as well.</description>
    <arm_group_label>Virtual prismatic adaptation</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Prismatic goggles</intervention_name>
    <description>Goggles inducing a lateral displacement of the virtual field of ten degrees. Participants will be asked to wear those goggles during adaptation session and to mentally perform pointing movement toward visual target. There will be no concurrent movement execution.</description>
    <arm_group_label>Imaged prismatic adaptation</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Male or female&#xD;
&#xD;
          -  Right-handed&#xD;
&#xD;
          -  Aged 18 to 70&#xD;
&#xD;
          -  Normal or corrected vision&#xD;
&#xD;
          -  Signed written informed consent&#xD;
&#xD;
          -  Affiliated to a health care organism.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Neurological or psychiatric disorder&#xD;
&#xD;
          -  Cognitive disorders&#xD;
&#xD;
          -  presence of corrective eyeglasses&#xD;
&#xD;
          -  Right upper limb orthopedic disorders&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>70 Years</maximum_age>
    <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Yves ROSSETTI, MD</last_name>
    <role>Principal Investigator</role>
    <affiliation>Hospices Civils de Lyon</affiliation>
  </overall_official>
  <overall_contact>
    <last_name>Yves ROSSETTI, MD</last_name>
    <phone>04 72 91 34 12</phone>
    <phone_ext>+33</phone_ext>
    <email>yves.rossetti@inserm.fr</email>
  </overall_contact>
  <overall_contact_backup>
    <last_name>Alessandro FARNE, PhD</last_name>
    <phone>04 72 91 34 12</phone>
    <phone_ext>+33</phone_ext>
    <email>Alessandro.farne@inserm.fr</email>
  </overall_contact_backup>
  <location>
    <facility>
      <name>Lyon Neuroscience Research Center</name>
      <address>
        <city>Bron</city>
        <zip>69500</zip>
        <country>France</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Yves ROSSETTI, MD</last_name>
      <phone>04 72 91 34 00</phone>
      <phone_ext>+33</phone_ext>
      <email>yves.rossetti@inserm.fr</email>
    </contact>
    <contact_backup>
      <last_name>Alessandro FARNE, PhD</last_name>
      <phone>04 72 91 34 12</phone>
      <phone_ext>+33</phone_ext>
      <email>Alessandro.farne@inserm.fr</email>
    </contact_backup>
    <investigator>
      <last_name>Yves ROSSETTI, MD</last_name>
      <role>Principal Investigator</role>
    </investigator>
    <investigator>
      <last_name>Alessandro FARNE, PhD</last_name>
      <role>Sub-Investigator</role>
    </investigator>
  </location>
  <location_countries>
    <country>France</country>
  </location_countries>
  <verification_date>January 2023</verification_date>
  <study_first_submitted>November 27, 2018</study_first_submitted>
  <study_first_submitted_qc>January 15, 2019</study_first_submitted_qc>
  <study_first_posted type="Actual">January 16, 2019</study_first_posted>
  <last_update_submitted>January 30, 2023</last_update_submitted>
  <last_update_submitted_qc>January 30, 2023</last_update_submitted_qc>
  <last_update_posted type="Actual">January 31, 2023</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <keyword>Virtual Reality</keyword>
  <keyword>prismatic adaptation</keyword>
  <keyword>motor imagery</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Brain Injuries</mesh_term>
  </condition_browse>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03807401
org study id: 69HCL18_0721
secondary id: 2018-A03175-50
nct id: NCT03807401
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
Unilateral neglect is a neuropsychological disorder reflected by a disturbance in the spatial
      exploration and distribution of directed attention affecting the contralateral part of space
      and body relatively to the brain lesion. The chronic aspect of this pathology leads to a poor
      progression following rehabilitation and a decreased independence of patients in daily life.
      Thus, it is necessary to set up efficient and long lasting therapies for unilateral neglect
      patients to improve their daily quality of life. Prismatic adaptation is now a classical
      method which allows patients to improve their neglect through corrective pointing movements
      in response to a lateral displacement of the visual field. A large and growing body of
      literature has investigated prismatic adaptation as a very promising rehabilitation method,
      improving both visuomotor and cognitive features of unilateral neglect. However, its effects
      are somehow irregular and clinical applications of this method are still limited. The
      necessity for patients to come to the hospital to take advantage of prismatic adaption
      sessions draws some limitations about our knowledge concerning 1) the temporal dynamic of
      prism adaptation effects on a long-term basis and 2) the optimal duration of treatment (most
      of the time constrained by the hospitalization duration) and its therapeutical effects on a
      very long-term basis. Moreover, a large number of patients also suffer from motor deficits
      which reduce the possibility to optimize the prismatic adaptation session.

      Thus, the aim of this project is to develop and validate others modalities of prismatic
      adaptation which can be applied at home and for a longer duration. These modalities should
      allow the investigator to get insights about the temporal dynamic of prismatic adaptation on
      the cognitive system. First, the investigator will investigate the effects of a prismatic
      adaptation modality using virtual reality to reproduce the lateral displacement induced by
      the prismatic goggles. He will also investigate prismatic adaptation induced by motor
      imagery, i.e. with mental representations of pointing movements without concomitant motor
      execution. This project could enhance the fundamental knowledge and enable to design new
      modalities of therapeutical use of prismatic adaptation (virtual or imaged) so as to allow a
      home-based treatment and follow-up. Thus, the aim of this project is to demonstrate the
      implication of similar mechanisms through different modalities (virtual and imaged compared
      to classical application) and the feasibility of these new modalities of healthy subjects.
      Thereafter, the aim will be to use knowledge acquired during this project to set up clinical
      trials to test for the efficiency of these modalities on a long-term basis in a pathological
      population.
allocation: Randomized
intervention model: Factorial Assignment
primary purpose: Basic Science
masking: None (Open Label)
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Line bisection test, the reference point is the middle of the line.
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Line bisection test, the reference point is the middle of the line.
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Line bisection test, the reference point is the middle of the line.
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 1 : Line bisection to assess visuo-spatial bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Line bisection test, the reference point is the middle of the line.
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Goal-directed pointing test, the reference point is the target.
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Goal-directed pointing test, the reference point is the target.
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Goal-directed pointing test, the reference point is the target.
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 2 : Goal-directed pointing to assess sensorimotor bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Goal-directed pointing test, the reference point is the target.
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 3 : Straight Ahead pointing to assess proprioceptive bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
For the Straight Ahead pointing and Visual judgement tests, the reference point is a central imaginary line
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right before adaption
description: Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
measure: Visuospatial performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
measure: sensorimotor performances : measure of deviations in mm
time frame: Day 0 - right after adaption
description: Task 4 : Visual judgement to assess visual bias In the test, the investigator will measure the deviation (in mm) between the response of the subject and the reference point.
arm group label: Classical prismatic adaptation
arm group type: Active Comparator
description: Classical prismatic adaptation arm will be divided into two subgroups corresponding to the side of the prismatic displacement (right or left)
arm group label: Virtual prismatic adaptation
arm group type: Experimental
description: virtual prismatic adaptation arm will be divided into two subgroups corresponding to the side of the prismatic displacement (right or left)
arm group label: Imaged prismatic adaptation
arm group type: Experimental
description: Imaged prismatic adaptation arm will be divided into two subgroups corresponding to the side of the prismatic displacement (right or left)
intervention type: Behavioral
intervention name: Prismatic goggles
description: Goggles inducing a lateral displacement of the virtual field of ten degrees. Participants will be asked to wear those goggles during adaptation session and to perform pointing movement toward visual target.
arm group label: Classical prismatic adaptation
intervention type: Behavioral
intervention name: Virtual reality device
description: The lateral displacement will be simulated thanks to a virtual reality environment. Participants will wear an Oculus Rift instead of the prismatic goggles and will perform pointing movement as well.
arm group label: Virtual prismatic adaptation
intervention type: Behavioral
intervention name: Prismatic goggles
description: Goggles inducing a lateral displacement of the virtual field of ten degrees. Participants will be asked to wear those goggles during adaptation session and to mentally perform pointing movement toward visual target. There will be no concurrent movement execution.
arm group label: Imaged prismatic adaptation
criteria: 
gender: All
minimum age: 18 Years
maximum age: 70 Years
healthy volunteers: Accepts Healthy Volunteers
last name: Yves ROSSETTI, MD
role: Principal Investigator
affiliation: Hospices Civils de Lyon
last name: Yves ROSSETTI, MD
phone: 04 72 91 34 12
phone ext: +33
email: yves.rossetti@inserm.fr
last name: Alessandro FARNE, PhD
phone: 04 72 91 34 12
phone ext: +33
email: Alessandro.farne@inserm.fr
facility: 
status: Recruiting
contact: 
contact backup: 
investigator: 
investigator: 
country: France
responsible party type: Sponsor
mesh term: Brain Injuries