<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03829072</url>
  </required_header>
  <id_info>
    <org_study_id>18-PP-10</org_study_id>
    <nct_id>NCT03829072</nct_id>
  </id_info>
  <brief_title>Cooking Education and Adapted Physical Activity in Allografted Patients</brief_title>
  <acronym>NUTRITION</acronym>
  <official_title>Impact of Cooking Education and Adapted Physical Activity on Nutritional Status and Quality of Life of Patients Treated by Allo Stem Cell Transplantation</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Centre Hospitalier Universitaire de Nice</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>Centre Hospitalier Universitaire de Nice</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      Majority of patients after allo stem cell transplantation have malnutrition and decrease of&#xD;
      physical activities. This state impacts on quality of life and on outcome of some&#xD;
      complications like infections, graft versus host disease and could decrease the overall&#xD;
      survival. In this study, the investigators propose cooking education and adapted physical&#xD;
      activity to improve that. Cooking education and adapted physical activity at home will be&#xD;
      performed by two famous chefs for the first one and by a sportive coach for the second every&#xD;
      twice week.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Bone marrow transplantation is the main strategy to cure leukemia and others hematopoietic&#xD;
      malignancies. It includes a first step of chemotherapy during several days (combined&#xD;
      sometimes to radiotherapy), a second step of stem cells infusion and a third step of&#xD;
      management of complications during several months: side effects, infections or graft versus&#xD;
      host disease (GvHD). Symptoms are cutaneous, hepatic and digestive (nausea, diarrhea,&#xD;
      vomiting) and could be unfortunately followed by the death of the patients.&#xD;
&#xD;
      Nutritional status is known to be important during the treatment of all cancers. After bone&#xD;
      marrow transplantation, patients could have some digestive disorders that could induce&#xD;
      malnutrition that could have an impact of time of hospitalization, intensity of complications&#xD;
      and outcome of these ones.&#xD;
&#xD;
      When patients go back home after allo stem cell transplantation, they take several medicines,&#xD;
      they have digestive side effects of past treatments could alter mucous, taste and all&#xD;
      digestive tracts. During at least 100 days, patients take immunosuppressive therapies and&#xD;
      they are going to develop new immune system. Therefore, they must follow some food rules to&#xD;
      avoid infectious diseases. Patients feel some difficulties to eat good food and refuse often&#xD;
      social activities. All of these have an impact on quality of life and induce an increase of&#xD;
      malnutrition observed already directly after allo stem cell transplantation. Some&#xD;
      complications could also increase malnutrition like digestive GvHD or digestive infections.&#xD;
      Malnutrition could also induce physical troubles. Patients need until one year to recover&#xD;
      physical conditions before the disease.&#xD;
&#xD;
      The aims of the study are to improve nutritional status and physical activity of patients&#xD;
      after allo stem cell transplantation.&#xD;
&#xD;
      The investigators propose at all patients included in the study cooking education and adapted&#xD;
      physical activity every twice week in alternance. Cooking education will be performed by two&#xD;
      famous chefs in their kitchens. Patients (until 3 months after bone marrow transplantation)&#xD;
      and one member of their family are invited to cook and taste. They will receive lot of advice&#xD;
      to make several recipes at home and will adapt their cooking methods to respect food rules.&#xD;
      Adapted physical activity will be performed by a sportive coach at home. The coach will give&#xD;
      them some physical exercises to do between two sessions.&#xD;
&#xD;
      Patients, aged more than 18 years old and signing the consent form, are included in the study&#xD;
      before allo stem cell transplantation. Nutritional status evaluation will be performed by a&#xD;
      nutritionist using some tests: sit up test, hand grip, bioelectrical impedance analysis, mid&#xD;
      upper arm circumference, analogic evaluation of appetite, blood tests: C reactive protein,&#xD;
      transthyretin, albumin. The nutritionist will analyze also body mass index, the weight loss&#xD;
      percent, the subjective global assessment, the health quality of life assessment.&#xD;
&#xD;
      Evaluation will be performed before allo stem cell transplantation, at day 0, 30, 100 and&#xD;
      300.&#xD;
&#xD;
      The aims of the study are to observe an improvement of nutritional status, quality of life, a&#xD;
      decrease of the number of infections and GvHD and at the end an increase of overall survival.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Recruiting</last_known_status>
  <start_date type="Actual">April 30, 2019</start_date>
  <completion_date type="Anticipated">April 30, 2023</completion_date>
  <primary_completion_date type="Actual">April 30, 2021</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>N/A</allocation>
    <intervention_model>Single Group Assignment</intervention_model>
    <primary_purpose>Prevention</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Body mass index</measure>
    <time_frame>at pre transplant</time_frame>
    <description>Body mass index</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Body mass index</measure>
    <time_frame>at Day 0</time_frame>
    <description>Body mass index</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Body mass index</measure>
    <time_frame>at Day 30</time_frame>
    <description>Body mass index</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Body mass index</measure>
    <time_frame>at Day 100</time_frame>
    <description>Body mass index</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Body mass index</measure>
    <time_frame>at Day 300</time_frame>
    <description>Body mass index</description>
  </primary_outcome>
  <primary_outcome>
    <measure>visual analogic scale of appetite</measure>
    <time_frame>at pre transplant</time_frame>
    <description>It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>visual analogic scale of appetite</measure>
    <time_frame>at Day 0</time_frame>
    <description>It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values</description>
  </primary_outcome>
  <primary_outcome>
    <measure>visual analogic scale of appetite</measure>
    <time_frame>at Day 30</time_frame>
    <description>It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values</description>
  </primary_outcome>
  <primary_outcome>
    <measure>visual analogic scale of appetite</measure>
    <time_frame>at Day 100</time_frame>
    <description>It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values</description>
  </primary_outcome>
  <primary_outcome>
    <measure>visual analogic scale of appetite</measure>
    <time_frame>at Day 300</time_frame>
    <description>It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sit up test</measure>
    <time_frame>at pre transplant</time_frame>
    <description>sit up test</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sit up test</measure>
    <time_frame>at Day 0</time_frame>
    <description>sit up test</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sit up test</measure>
    <time_frame>at Day 30</time_frame>
    <description>sit up test</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sit up test</measure>
    <time_frame>at Day 100</time_frame>
    <description>sit up test</description>
  </primary_outcome>
  <primary_outcome>
    <measure>sit up test</measure>
    <time_frame>at Day 300</time_frame>
    <description>sit up test</description>
  </primary_outcome>
  <primary_outcome>
    <measure>bio electrical impedance analysis,</measure>
    <time_frame>at pre transplant</time_frame>
    <description>it's measuring the resistance of biological tissues</description>
  </primary_outcome>
  <primary_outcome>
    <measure>bio electrical impedance analysis,</measure>
    <time_frame>at Day 0</time_frame>
    <description>it's measuring the resistance of biological tissues</description>
  </primary_outcome>
  <primary_outcome>
    <measure>bio electrical impedance analysis,</measure>
    <time_frame>at Day 30</time_frame>
    <description>it's measuring the resistance of biological tissues</description>
  </primary_outcome>
  <primary_outcome>
    <measure>bio electrical impedance analysis,</measure>
    <time_frame>at Day 100</time_frame>
    <description>it's measuring the resistance of biological tissues</description>
  </primary_outcome>
  <primary_outcome>
    <measure>bio electrical impedance analysis,</measure>
    <time_frame>at Day 300</time_frame>
    <description>it's measuring the resistance of biological tissues</description>
  </primary_outcome>
  <primary_outcome>
    <measure>hand grip</measure>
    <time_frame>at pre transplant</time_frame>
    <description>hand grip</description>
  </primary_outcome>
  <primary_outcome>
    <measure>hand grip</measure>
    <time_frame>at Day 0</time_frame>
    <description>hand grip</description>
  </primary_outcome>
  <primary_outcome>
    <measure>hand grip</measure>
    <time_frame>at Day 30</time_frame>
    <description>hand grip</description>
  </primary_outcome>
  <primary_outcome>
    <measure>hand grip</measure>
    <time_frame>at Day 100</time_frame>
    <description>hand grip</description>
  </primary_outcome>
  <primary_outcome>
    <measure>hand grip</measure>
    <time_frame>at Day 300</time_frame>
    <description>hand grip</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Quality of life assessment,</measure>
    <time_frame>at pre transplant</time_frame>
    <description>it's a satisfaction patient's scale</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Quality of life assessment,</measure>
    <time_frame>at Day 0</time_frame>
    <description>it's a satisfaction patient's scale</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Quality of life assessment,</measure>
    <time_frame>at Day 30</time_frame>
    <description>it's a satisfaction patient's scale</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Quality of life assessment,</measure>
    <time_frame>at Day 100</time_frame>
    <description>it's a satisfaction patient's scale</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Quality of life assessment,</measure>
    <time_frame>at Day 300</time_frame>
    <description>it's a satisfaction patient's scale</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of infections,</measure>
    <time_frame>at pre transplant</time_frame>
    <description>number of infections,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of infections,</measure>
    <time_frame>at Day 0</time_frame>
    <description>number of infections,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of infections,</measure>
    <time_frame>at Day 30</time_frame>
    <description>number of infections,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of infections,</measure>
    <time_frame>at Day 100</time_frame>
    <description>number of infections,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of infections,</measure>
    <time_frame>at Day 300</time_frame>
    <description>number of infections,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of graft versus host disease,</measure>
    <time_frame>at pre transplant</time_frame>
    <description>number of graft versus host disease,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of graft versus host disease,</measure>
    <time_frame>at Day 0</time_frame>
    <description>number of graft versus host disease,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of graft versus host disease,</measure>
    <time_frame>at Day 30</time_frame>
    <description>number of graft versus host disease,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of graft versus host disease,</measure>
    <time_frame>at Day 100</time_frame>
    <description>number of graft versus host disease,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>number of graft versus host disease,</measure>
    <time_frame>at Day 300</time_frame>
    <description>number of graft versus host disease,</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>overall survival</measure>
    <time_frame>at pre transplant</time_frame>
    <description>overall survival</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>overall survival</measure>
    <time_frame>at Day 0</time_frame>
    <description>overall survival</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>overall survival</measure>
    <time_frame>at Day 30</time_frame>
    <description>overall survival</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>overall survival</measure>
    <time_frame>at Day 100</time_frame>
    <description>overall survival</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>overall survival</measure>
    <time_frame>at Day 300</time_frame>
    <description>overall survival</description>
  </secondary_outcome>
  <number_of_arms>1</number_of_arms>
  <enrollment type="Anticipated">50</enrollment>
  <condition>Allograft</condition>
  <arm_group>
    <arm_group_label>cooking Education and adapted physical activity</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
  </arm_group>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Cooking Education</intervention_name>
    <description>cooking Education and adapted physical activity on patients after allo stem cell transplantation</description>
    <arm_group_label>cooking Education and adapted physical activity</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>adapted physical activity</intervention_name>
    <description>cooking Education and adapted physical activity on patients after allo stem cell transplantation</description>
    <arm_group_label>cooking Education and adapted physical activity</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Patient at least 18 years old&#xD;
&#xD;
          -  Having been an allograft of CSH&#xD;
&#xD;
          -  Patient having read and understood the information note related to the study, and&#xD;
             signed the informed consent form.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Patient requiring nutritional support by enteral or parenteral route at J30&#xD;
&#xD;
          -  Follow-up of the patient considered difficult by the investigator.&#xD;
&#xD;
          -  Patient with a linguistic or psychic disability to understand the information.&#xD;
&#xD;
          -  Vulnerable patient under legal protection&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Thomas CLUZEAU</last_name>
    <role>Principal Investigator</role>
    <affiliation>Centre Hospitalier Universitaire de Nice</affiliation>
  </overall_official>
  <overall_contact>
    <last_name>Marine DOUILLET</last_name>
    <phone>0033 4 92 03 45 04</phone>
    <email>douillet.m@chu-nice.fr</email>
  </overall_contact>
  <location>
    <facility>
      <name>CHU de Nice - Hôpital de l'Archet</name>
      <address>
        <city>Nice</city>
        <zip>06200</zip>
        <country>France</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Thomas CLUZEAU</last_name>
      <email>cluzeau.t@chu-nice.fr</email>
    </contact>
    <investigator>
      <last_name>Thomas CLUZEAU, PH</last_name>
      <role>Principal Investigator</role>
    </investigator>
  </location>
  <location_countries>
    <country>France</country>
  </location_countries>
  <verification_date>July 2021</verification_date>
  <study_first_submitted>December 27, 2018</study_first_submitted>
  <study_first_submitted_qc>January 31, 2019</study_first_submitted_qc>
  <study_first_posted type="Actual">February 4, 2019</study_first_posted>
  <last_update_submitted>July 12, 2021</last_update_submitted>
  <last_update_submitted_qc>July 12, 2021</last_update_submitted_qc>
  <last_update_posted type="Actual">July 16, 2021</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <keyword>Allo Stem Cell Transplantation</keyword>
  <keyword>Cooking</keyword>
  <keyword>Physical activity</keyword>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03829072
org study id: 18-PP-10
nct id: NCT03829072
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
Majority of patients after allo stem cell transplantation have malnutrition and decrease of
      physical activities. This state impacts on quality of life and on outcome of some
      complications like infections, graft versus host disease and could decrease the overall
      survival. In this study, the investigators propose cooking education and adapted physical
      activity to improve that. Cooking education and adapted physical activity at home will be
      performed by two famous chefs for the first one and by a sportive coach for the second every
      twice week.
Bone marrow transplantation is the main strategy to cure leukemia and others hematopoietic
      malignancies. It includes a first step of chemotherapy during several days (combined
      sometimes to radiotherapy), a second step of stem cells infusion and a third step of
      management of complications during several months: side effects, infections or graft versus
      host disease (GvHD). Symptoms are cutaneous, hepatic and digestive (nausea, diarrhea,
      vomiting) and could be unfortunately followed by the death of the patients.

      Nutritional status is known to be important during the treatment of all cancers. After bone
      marrow transplantation, patients could have some digestive disorders that could induce
      malnutrition that could have an impact of time of hospitalization, intensity of complications
      and outcome of these ones.

      When patients go back home after allo stem cell transplantation, they take several medicines,
      they have digestive side effects of past treatments could alter mucous, taste and all
      digestive tracts. During at least 100 days, patients take immunosuppressive therapies and
      they are going to develop new immune system. Therefore, they must follow some food rules to
      avoid infectious diseases. Patients feel some difficulties to eat good food and refuse often
      social activities. All of these have an impact on quality of life and induce an increase of
      malnutrition observed already directly after allo stem cell transplantation. Some
      complications could also increase malnutrition like digestive GvHD or digestive infections.
      Malnutrition could also induce physical troubles. Patients need until one year to recover
      physical conditions before the disease.

      The aims of the study are to improve nutritional status and physical activity of patients
      after allo stem cell transplantation.

      The investigators propose at all patients included in the study cooking education and adapted
      physical activity every twice week in alternance. Cooking education will be performed by two
      famous chefs in their kitchens. Patients (until 3 months after bone marrow transplantation)
      and one member of their family are invited to cook and taste. They will receive lot of advice
      to make several recipes at home and will adapt their cooking methods to respect food rules.
      Adapted physical activity will be performed by a sportive coach at home. The coach will give
      them some physical exercises to do between two sessions.

      Patients, aged more than 18 years old and signing the consent form, are included in the study
      before allo stem cell transplantation. Nutritional status evaluation will be performed by a
      nutritionist using some tests: sit up test, hand grip, bioelectrical impedance analysis, mid
      upper arm circumference, analogic evaluation of appetite, blood tests: C reactive protein,
      transthyretin, albumin. The nutritionist will analyze also body mass index, the weight loss
      percent, the subjective global assessment, the health quality of life assessment.

      Evaluation will be performed before allo stem cell transplantation, at day 0, 30, 100 and
      300.

      The aims of the study are to observe an improvement of nutritional status, quality of life, a
      decrease of the number of infections and GvHD and at the end an increase of overall survival.
allocation: N/A
intervention model: Single Group Assignment
primary purpose: Prevention
masking: None (Open Label)
measure: Body mass index
time frame: at pre transplant
description: Body mass index
measure: Body mass index
time frame: at Day 0
description: Body mass index
measure: Body mass index
time frame: at Day 30
description: Body mass index
measure: Body mass index
time frame: at Day 100
description: Body mass index
measure: Body mass index
time frame: at Day 300
description: Body mass index
measure: visual analogic scale of appetite
time frame: at pre transplant
description: It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values.
measure: visual analogic scale of appetite
time frame: at Day 0
description: It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values
measure: visual analogic scale of appetite
time frame: at Day 30
description: It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values
measure: visual analogic scale of appetite
time frame: at Day 100
description: It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values
measure: visual analogic scale of appetite
time frame: at Day 300
description: It allows a visual assessment, by the patient himself, of his food intake, using an analog scale, or a choice of portions consumed.Visual analog scales (VAS) are reliable tools to evaluate hunger and satiety at point of food consumption. Score from 1 to 10. There are not better or worse values
measure: sit up test
time frame: at pre transplant
description: sit up test
measure: sit up test
time frame: at Day 0
description: sit up test
measure: sit up test
time frame: at Day 30
description: sit up test
measure: sit up test
time frame: at Day 100
description: sit up test
measure: sit up test
time frame: at Day 300
description: sit up test
measure: bio electrical impedance analysis,
time frame: at pre transplant
description: it's measuring the resistance of biological tissues
measure: bio electrical impedance analysis,
time frame: at Day 0
description: it's measuring the resistance of biological tissues
measure: bio electrical impedance analysis,
time frame: at Day 30
description: it's measuring the resistance of biological tissues
measure: bio electrical impedance analysis,
time frame: at Day 100
description: it's measuring the resistance of biological tissues
measure: bio electrical impedance analysis,
time frame: at Day 300
description: it's measuring the resistance of biological tissues
measure: hand grip
time frame: at pre transplant
description: hand grip
measure: hand grip
time frame: at Day 0
description: hand grip
measure: hand grip
time frame: at Day 30
description: hand grip
measure: hand grip
time frame: at Day 100
description: hand grip
measure: hand grip
time frame: at Day 300
description: hand grip
measure: Quality of life assessment,
time frame: at pre transplant
description: it's a satisfaction patient's scale
measure: Quality of life assessment,
time frame: at Day 0
description: it's a satisfaction patient's scale
measure: Quality of life assessment,
time frame: at Day 30
description: it's a satisfaction patient's scale
measure: Quality of life assessment,
time frame: at Day 100
description: it's a satisfaction patient's scale
measure: Quality of life assessment,
time frame: at Day 300
description: it's a satisfaction patient's scale
measure: number of infections,
time frame: at pre transplant
description: number of infections,
measure: number of infections,
time frame: at Day 0
description: number of infections,
measure: number of infections,
time frame: at Day 30
description: number of infections,
measure: number of infections,
time frame: at Day 100
description: number of infections,
measure: number of infections,
time frame: at Day 300
description: number of infections,
measure: number of graft versus host disease,
time frame: at pre transplant
description: number of graft versus host disease,
measure: number of graft versus host disease,
time frame: at Day 0
description: number of graft versus host disease,
measure: number of graft versus host disease,
time frame: at Day 30
description: number of graft versus host disease,
measure: number of graft versus host disease,
time frame: at Day 100
description: number of graft versus host disease,
measure: number of graft versus host disease,
time frame: at Day 300
description: number of graft versus host disease,
measure: overall survival
time frame: at pre transplant
description: overall survival
measure: overall survival
time frame: at Day 0
description: overall survival
measure: overall survival
time frame: at Day 30
description: overall survival
measure: overall survival
time frame: at Day 100
description: overall survival
measure: overall survival
time frame: at Day 300
description: overall survival
arm group label: cooking Education and adapted physical activity
arm group type: Experimental
intervention type: Other
intervention name: Cooking Education
description: cooking Education and adapted physical activity on patients after allo stem cell transplantation
arm group label: cooking Education and adapted physical activity
intervention type: Other
intervention name: adapted physical activity
description: cooking Education and adapted physical activity on patients after allo stem cell transplantation
arm group label: cooking Education and adapted physical activity
criteria: 
gender: All
minimum age: 18 Years
maximum age: N/A
healthy volunteers: No
last name: Thomas CLUZEAU
role: Principal Investigator
affiliation: Centre Hospitalier Universitaire de Nice
last name: Marine DOUILLET
phone: 0033 4 92 03 45 04
email: douillet.m@chu-nice.fr
facility: 
status: Recruiting
contact: 
investigator: 
country: France
responsible party type: Sponsor