<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03796767</url>
  </required_header>
  <id_info>
    <org_study_id>HCI115811</org_study_id>
    <secondary_id>NCI-2018-03418</secondary_id>
    <nct_id>NCT03796767</nct_id>
  </id_info>
  <brief_title>Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer</brief_title>
  <acronym>SOAR</acronym>
  <official_title>Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer (SOAR)</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>University of Utah</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>University of Utah</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
    <is_us_export>No</is_us_export>
  </oversight_info>
  <brief_summary>
    <textblock>
      This phase II trial studies how well surgery and radiation therapy work in treating patients&#xD;
      with prostate cancer that has come back or spread to other parts of the body. Radiation&#xD;
      therapy uses high energy beams to kill tumor cells and shrink tumors. Surgical procedures,&#xD;
      such as oligometastasectomy, may remove tumor cells that have spread to other parts of the&#xD;
      body. Surgery and radiation therapy may work better in treating patients with prostate cancer&#xD;
      that has come back or spread to other parts of the body.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      PRIMARY OBJECTIVES:&#xD;
&#xD;
      I. To assess response to treatment of oligometastatic disease.&#xD;
&#xD;
      SECONDARY OBJECTIVES:&#xD;
&#xD;
      I. To assess additional measurements of response to treatment of oligometastatic disease.&#xD;
&#xD;
      II. To assess prostate-specific antigen (PSA) progression free-survival following treatment&#xD;
      of oligometastatic disease.&#xD;
&#xD;
      III. To assess time to disease recurrence following treatment of oligometastatic disease.&#xD;
&#xD;
      IV. To assess time to initiation of antiandrogen therapy (ADT) for metastatic prostate cancer&#xD;
      following treatment of oligometastatic disease.&#xD;
&#xD;
      V. To assess the rate of undetectable PSA following treatment of oligometastatic disease in&#xD;
      subjects who have previously undergone prostatectomy.&#xD;
&#xD;
      VI. To assess safety. VII. To assess the impact of study treatment on change in quality of&#xD;
      life over three years.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Recruiting</overall_status>
  <start_date type="Actual">September 9, 2019</start_date>
  <completion_date type="Anticipated">December 1, 2024</completion_date>
  <primary_completion_date type="Anticipated">December 1, 2023</primary_completion_date>
  <phase>Phase 2</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Non-Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Prostate-specific antigen (PSA) response rate</measure>
    <time_frame>At 6 months after completion of treatment</time_frame>
    <description>Defined according to Prostate Cancer Working Group (PCWG3) criteria as the proportion of patients achieving a PSA decline &gt;= 50% at 6 months after completion of treatment (salvage + - adjuvant). All study data will use descriptive statistics and will be exploratory only.</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>PSA progression-free survival (PFS)</measure>
    <time_frame>Time elapsed between completion of treatment (salvage + - adjuvant) and the first occurrence of confirmed PSA progression, assessed up to 3 years</time_frame>
    <description>Assessed according to PCWG3 criteria. All study data will use descriptive statistics and will be exploratory only.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to disease recurrence</measure>
    <time_frame>Time elapsed between study enrollment and first occurrence of confirmed radiographic disease progression, assessed up to 3 years</time_frame>
    <description>Time from study enrollment until the date of confirmed radiographic disease progression as defined by RECIST 1.1 and PCWG3.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to antiandrogen therapy (ADT)</measure>
    <time_frame>Time elapsed between study enrollment and initiation of ADT up to 3 years</time_frame>
    <description>All study data will use descriptive statistics and will be exploratory only.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Rate of undetectable PSA</measure>
    <time_frame>Up to 3 years</time_frame>
    <description>Patients previously treated with prostatectomy evaluate the proportion of patients whose PSA remains =&lt; 0.2 ng/mL after 6 and 12 months following completion of treatment (salvage + - adjuvant). All study data will use descriptive statistics and will be exploratory only.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Incidence of adverse events</measure>
    <time_frame>Up to 3 years</time_frame>
    <description>Assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0. All study data will use descriptive statistics and will be exploratory only.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Assess impact of study treatment on Change in quality of life over 3 years</measure>
    <time_frame>Up to 3 years</time_frame>
    <description>Quality of Life (QOL) questionnaires (FACT-P and Expanded Prostate Cancer Index Composite EPIC-26) administered at screening, response assessment visit, and each follow up visit.</description>
  </secondary_outcome>
  <number_of_arms>3</number_of_arms>
  <enrollment type="Anticipated">40</enrollment>
  <condition>Recurrent Prostate Carcinoma</condition>
  <condition>Metastatic Malignant Neoplasm in the Bone</condition>
  <condition>Metastatic Malignant Neoplasm in the Lymph Nodes</condition>
  <condition>Oligometastasis</condition>
  <condition>Prostate Adenocarcinoma</condition>
  <condition>PSA Failure</condition>
  <arm_group>
    <arm_group_label>Arm A (radiation therapy)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Patients with bone metastases undergo SBR) or hypofractionated radiation per institutional standard of care guidelines at investigator's discretion.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Arm B (salvage oligometastasectomy)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Patients with nodal metastases undergo salvage oligometastasectomy.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Patients with nodal metastases undergo salvage oligometastasectomy. Following recovery, patients undergo SBRT or hypofractionated radiation per institutional standard of care guidelines at investigator's discretion. Within 4 months following completion of salvage therapy (defined as the combination of oligometastasectomy and/or bone radiation) and depending on PSA response as well as previous treatment, patients may receive adjuvant nodal IMRT.</description>
  </arm_group>
  <intervention>
    <intervention_type>Radiation</intervention_type>
    <intervention_name>Hypofractionated Radiation Therapy</intervention_name>
    <description>Undergo hypofractionated radiation therapy</description>
    <arm_group_label>Arm A (radiation therapy)</arm_group_label>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
    <other_name>Hypofractionated Radiotherapy</other_name>
    <other_name>hypofractionation</other_name>
  </intervention>
  <intervention>
    <intervention_type>Radiation</intervention_type>
    <intervention_name>Intensity-Modulated Radiation Therapy</intervention_name>
    <description>Undergo IMRT</description>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
    <other_name>IMRT</other_name>
    <other_name>Intensity Modulated RT</other_name>
    <other_name>Intensity-Modulated Radiotherapy</other_name>
  </intervention>
  <intervention>
    <intervention_type>Procedure</intervention_type>
    <intervention_name>Metastasectomy</intervention_name>
    <description>Undergo salvage oligometastasectomy</description>
    <arm_group_label>Arm B (salvage oligometastasectomy)</arm_group_label>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Quality-of-Life Assessment</intervention_name>
    <description>Ancillary studies</description>
    <arm_group_label>Arm A (radiation therapy)</arm_group_label>
    <arm_group_label>Arm B (salvage oligometastasectomy)</arm_group_label>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
    <other_name>Quality of Life Assessment</other_name>
  </intervention>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Questionnaire Administration</intervention_name>
    <description>Ancillary studies</description>
    <arm_group_label>Arm A (radiation therapy)</arm_group_label>
    <arm_group_label>Arm B (salvage oligometastasectomy)</arm_group_label>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Radiation</intervention_type>
    <intervention_name>Stereotactic Body Radiation Therapy</intervention_name>
    <description>Undergo SBRT</description>
    <arm_group_label>Arm A (radiation therapy)</arm_group_label>
    <arm_group_label>Arm C (salvage oligometastasectomy, radiation therapy)</arm_group_label>
    <other_name>SABR</other_name>
    <other_name>SBRT</other_name>
    <other_name>Stereotactic Ablative Body Radiation Therapy</other_name>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Histologically proven adenocarcinoma of the prostate.&#xD;
&#xD;
          -  Recurrent prostate carcinoma after definitive therapy for primary disease defined as:&#xD;
&#xD;
               -  Post-prostatectomy (with/without adjuvant radiotherapy): Patients must have a&#xD;
                  detectable or rising PSA level that is &gt; 0.05 ng/mL, with a second confirmatory&#xD;
                  level of &gt; 0.05 ng/mL after a minimum of 1 week.&#xD;
&#xD;
               -  Post radiotherapy/ablation (without radical prostatectomy): PSA rise &gt;= 2ng/mL&#xD;
                  over nadir.&#xD;
&#xD;
          -  Subjects treated with prior definitive radiotherapy for prostate cancer who have&#xD;
             positive molecular imaging (e.g., fluciclovine PET/CT scan or other per PI discretion)&#xD;
             suggesting recurrent intraprostatic disease must undergo transrectal ultrasound (TRUS)&#xD;
             biopsy less than or equal to one year before study enrollment:&#xD;
&#xD;
               -  If the TRUS biopsy is negative, no additional treatment is required to the&#xD;
                  prostate in addition to that of scan positive sites.&#xD;
&#xD;
               -  If the TRUS biopsy is positive, subject must undergo salvage prostatectomy or&#xD;
                  salvage radiotherapy to the primary site concurrently with the study treatment&#xD;
                  per the treatment protocol algorithm.&#xD;
&#xD;
               -  NOTE: Biopsy is not required for prostate fossa recurrences after radical&#xD;
                  prostatectomy.&#xD;
&#xD;
          -  Oligometastatic disease defined as 10 or fewer metastatic lesions to lymph nodes&#xD;
             and/or bones only.&#xD;
&#xD;
          -  For patients with oligometastatic disease involving lymph nodes, metastasis is&#xD;
             confined to the pelvic or para-aortic (below IMA) regions on molecular imaging (e.g.,&#xD;
             fluciclovine PET/CT or PSMA PET/CT scan or other per PI discretion).&#xD;
&#xD;
          -  All subjects must be surgical candidates if surgery is indicated per the treatment&#xD;
             algorithm.&#xD;
&#xD;
          -  Eastern Cooperative Oncology Group (ECOG) performance status =&lt; 2.&#xD;
&#xD;
          -  Use of condoms for male subjects who have not had surgical removal of their prostate&#xD;
             and have a partner of child bearing potential beginning at the time of informed&#xD;
             consent form (ICF) signature and lasting until at least 6 months after the last&#xD;
             radiation treatment. Because of the potential side effect on spermatogenesis&#xD;
             associated with radiation, female partners of childbearing potential must agree to use&#xD;
             a highly effective contraceptive method during and for 6 months after completing&#xD;
             treatment.&#xD;
&#xD;
          -  Recovery to baseline or =&lt; grade 1 Common Terminology Criteria for Adverse Events&#xD;
             (CTCAE) version (v)5 from toxicities related to any prior treatments, unless adverse&#xD;
             event (AE)(s) are clinically non-significant and/or stable on supportive therapy as&#xD;
             determined by the treating physician.&#xD;
&#xD;
          -  Able to provide informed consent and willing to sign an approved consent form that&#xD;
             conforms to federal and institutional guidelines.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Known brain or visceral metastases other than lymph nodes as defined by CT, MRI, or&#xD;
             othermolecular imaging (e.g., fluciclovine PET/CT or PSMA PET/CT scan or other per PI&#xD;
             discretion).&#xD;
&#xD;
          -  Patients actively receiving hormone therapy for prostate cancer. Patients may have&#xD;
             received hormone therapy perviously but must have documented non-castrate levels of&#xD;
             testosterone (&gt;50 ng/dL)&#xD;
&#xD;
          -  Prior or concurrent malignancy whose natural history or treatment, in the opinion of&#xD;
             the enrolling investigator, may have the potential to interfere wih the safety or&#xD;
             efficay assessment of the investigational treatment protocol of the study.&#xD;
&#xD;
          -  Use of finasteride within 30 days prior to initiation of therapy. Baseline PSA should&#xD;
             not be obtained prior to 30 days after stopping finasteride.&#xD;
&#xD;
          -  Use of dutasteride within 90 days prior to initiation of therapy. Baseline PSA should&#xD;
             not be obtained prior to 90 days after stopping dutasteride.&#xD;
&#xD;
          -  Use of any prohibited therapy.&#xD;
&#xD;
          -  Active, uncontrolled, significant intercurrent or recent illness including, but not&#xD;
             limited to, the following conditions:&#xD;
&#xD;
               -  Cardiovascular disorders:&#xD;
&#xD;
                    -  Congestive heart failure New York Heart Association class 3 or 4, unstable&#xD;
                       angina pectoris, serious cardiac arrhythmias.&#xD;
&#xD;
                    -  Uncontrolled hypertension defined as sustained blood pressure (BP) &gt; 150&#xD;
                       mmHg systolic or &gt; 100 mmHg diastolic despite optimal antihypertensive&#xD;
                       treatment.&#xD;
&#xD;
                    -  Stroke (including transient ischemic attack [TIA]), myocardial infarction&#xD;
                       (MI), or other ischemic event, or thromboembolic event (e.g., deep venous&#xD;
                       thrombosis, pulmonary embolism) within 6 months before first dose.&#xD;
&#xD;
               -  Acute bacterial or fungal infection requiring intravenous antibiotics at the time&#xD;
                  of registration&#xD;
&#xD;
               -  Chronic obstructive pulmonary disease exacerbation or other respiratory illness&#xD;
                  requiring hospitalization or precluding study therapy at the time of registration&#xD;
                  or within 30 days of registration.&#xD;
&#xD;
               -  Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects.&#xD;
      </textblock>
    </criteria>
    <gender>Male</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Alejandro Sanchez</last_name>
    <role>Principal Investigator</role>
    <affiliation>Huntsman Cancer Institute/ University of Utah</affiliation>
  </overall_official>
  <overall_contact>
    <last_name>Kristen Jewkes</last_name>
    <phone>801-587-4776</phone>
    <email>Kristen.Jewkes@hci.utah.edu</email>
  </overall_contact>
  <location>
    <facility>
      <name>Huntsman Cancer Institute/University of Utah</name>
      <address>
        <city>Salt Lake City</city>
        <state>Utah</state>
        <zip>84112</zip>
        <country>United States</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Alejandro Sanchez</last_name>
      <phone>801-587-4385</phone>
      <email>Alejandro.Sanchez@hci.utah.edu</email>
    </contact>
    <investigator>
      <last_name>Alejandro Sanchez</last_name>
      <role>Principal Investigator</role>
    </investigator>
  </location>
  <location_countries>
    <country>United States</country>
  </location_countries>
  <verification_date>January 2023</verification_date>
  <study_first_submitted>January 4, 2019</study_first_submitted>
  <study_first_submitted_qc>January 4, 2019</study_first_submitted_qc>
  <study_first_posted type="Actual">January 8, 2019</study_first_posted>
  <last_update_submitted>January 4, 2023</last_update_submitted>
  <last_update_submitted_qc>January 4, 2023</last_update_submitted_qc>
  <last_update_posted type="Actual">January 6, 2023</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Neoplasms</mesh_term>
    <mesh_term>Neoplasms, Second Primary</mesh_term>
    <mesh_term>Recurrence</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03796767
org study id: HCI115811
secondary id: NCI-2018-03418
nct id: NCT03796767
lead sponsor: 
has dmc: Yes
is fda regulated drug: No
is fda regulated device: No
is us export: No
This phase II trial studies how well surgery and radiation therapy work in treating patients
      with prostate cancer that has come back or spread to other parts of the body. Radiation
      therapy uses high energy beams to kill tumor cells and shrink tumors. Surgical procedures,
      such as oligometastasectomy, may remove tumor cells that have spread to other parts of the
      body. Surgery and radiation therapy may work better in treating patients with prostate cancer
      that has come back or spread to other parts of the body.
PRIMARY OBJECTIVES:

      I. To assess response to treatment of oligometastatic disease.

      SECONDARY OBJECTIVES:

      I. To assess additional measurements of response to treatment of oligometastatic disease.

      II. To assess prostate-specific antigen (PSA) progression free-survival following treatment
      of oligometastatic disease.

      III. To assess time to disease recurrence following treatment of oligometastatic disease.

      IV. To assess time to initiation of antiandrogen therapy (ADT) for metastatic prostate cancer
      following treatment of oligometastatic disease.

      V. To assess the rate of undetectable PSA following treatment of oligometastatic disease in
      subjects who have previously undergone prostatectomy.

      VI. To assess safety. VII. To assess the impact of study treatment on change in quality of
      life over three years.
allocation: Non-Randomized
intervention model: Parallel Assignment
primary purpose: Treatment
masking: None (Open Label)
measure: Prostate-specific antigen (PSA) response rate
time frame: At 6 months after completion of treatment
description: Defined according to Prostate Cancer Working Group (PCWG3) criteria as the proportion of patients achieving a PSA decline >= 50% at 6 months after completion of treatment (salvage + - adjuvant). All study data will use descriptive statistics and will be exploratory only.
measure: PSA progression-free survival (PFS)
time frame: Time elapsed between completion of treatment (salvage + - adjuvant) and the first occurrence of confirmed PSA progression, assessed up to 3 years
description: Assessed according to PCWG3 criteria. All study data will use descriptive statistics and will be exploratory only.
measure: Time to disease recurrence
time frame: Time elapsed between study enrollment and first occurrence of confirmed radiographic disease progression, assessed up to 3 years
description: Time from study enrollment until the date of confirmed radiographic disease progression as defined by RECIST 1.1 and PCWG3.
measure: Time to antiandrogen therapy (ADT)
time frame: Time elapsed between study enrollment and initiation of ADT up to 3 years
description: All study data will use descriptive statistics and will be exploratory only.
measure: Rate of undetectable PSA
time frame: Up to 3 years
description: Patients previously treated with prostatectomy evaluate the proportion of patients whose PSA remains =< 0.2 ng/mL after 6 and 12 months following completion of treatment (salvage + - adjuvant). All study data will use descriptive statistics and will be exploratory only.
measure: Incidence of adverse events
time frame: Up to 3 years
description: Assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0. All study data will use descriptive statistics and will be exploratory only.
measure: Assess impact of study treatment on Change in quality of life over 3 years
time frame: Up to 3 years
description: Quality of Life (QOL) questionnaires (FACT-P and Expanded Prostate Cancer Index Composite EPIC-26) administered at screening, response assessment visit, and each follow up visit.
arm group label: Arm A (radiation therapy)
arm group type: Experimental
description: Patients with bone metastases undergo SBR) or hypofractionated radiation per institutional standard of care guidelines at investigator's discretion.
arm group label: Arm B (salvage oligometastasectomy)
arm group type: Experimental
description: Patients with nodal metastases undergo salvage oligometastasectomy.
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
arm group type: Experimental
description: Patients with nodal metastases undergo salvage oligometastasectomy. Following recovery, patients undergo SBRT or hypofractionated radiation per institutional standard of care guidelines at investigator's discretion. Within 4 months following completion of salvage therapy (defined as the combination of oligometastasectomy and/or bone radiation) and depending on PSA response as well as previous treatment, patients may receive adjuvant nodal IMRT.
intervention type: Radiation
intervention name: Hypofractionated Radiation Therapy
description: Undergo hypofractionated radiation therapy
arm group label: Arm A (radiation therapy)
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
other name: Hypofractionated Radiotherapy
other name: hypofractionation
intervention type: Radiation
intervention name: Intensity-Modulated Radiation Therapy
description: Undergo IMRT
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
other name: IMRT
other name: Intensity Modulated RT
other name: Intensity-Modulated Radiotherapy
intervention type: Procedure
intervention name: Metastasectomy
description: Undergo salvage oligometastasectomy
arm group label: Arm B (salvage oligometastasectomy)
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
intervention type: Other
intervention name: Quality-of-Life Assessment
description: Ancillary studies
arm group label: Arm A (radiation therapy)
arm group label: Arm B (salvage oligometastasectomy)
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
other name: Quality of Life Assessment
intervention type: Other
intervention name: Questionnaire Administration
description: Ancillary studies
arm group label: Arm A (radiation therapy)
arm group label: Arm B (salvage oligometastasectomy)
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
intervention type: Radiation
intervention name: Stereotactic Body Radiation Therapy
description: Undergo SBRT
arm group label: Arm A (radiation therapy)
arm group label: Arm C (salvage oligometastasectomy, radiation therapy)
other name: SABR
other name: SBRT
other name: Stereotactic Ablative Body Radiation Therapy
criteria: 
gender: Male
minimum age: 18 Years
maximum age: N/A
healthy volunteers: No
last name: Alejandro Sanchez
role: Principal Investigator
affiliation: Huntsman Cancer Institute/ University of Utah
last name: Kristen Jewkes
phone: 801-587-4776
email: Kristen.Jewkes@hci.utah.edu
facility: 
status: Recruiting
contact: 
investigator: 
country: United States
responsible party type: Sponsor
mesh term: Neoplasms
mesh term: Neoplasms, Second Primary
mesh term: Recurrence
sharing ipd: No