<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03287310</url>
  </required_header>
  <id_info>
    <org_study_id>205722</org_study_id>
    <secondary_id>2016-004256-30</secondary_id>
    <nct_id>NCT03287310</nct_id>
  </id_info>
  <brief_title>First Time in Human (FTIH) Study to Evaluate Safety, Tolerability, Immunogenicity, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3511294 Administered Subcutaneously (SC) in Subjects With Mild to Moderate Asthma</brief_title>
  <official_title>A Randomised Double-blind (Sponsor Open), Placebo Controlled, Single Ascending Dose, First Time in Human Study in Participants With Mild to Moderate Asthma to Assess Safety, Tolerability, Immunogenicity, Pharmacokinetics and Pharmacodynamics of GSK3511294 Administered Subcutaneously</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>GlaxoSmithKline</agency>
      <agency_class>Industry</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>GlaxoSmithKline</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      GSK3511294 is a humanized monoclonal antibody antagonist of Interleukin (IL)-5 which is known&#xD;
      to block binding of IL-5 to the IL-5 receptor complex, causing a reduction in the circulating&#xD;
      population of eosinophils. This is a single ascending dose FTIH study to investigate safety,&#xD;
      tolerability, immunogenicity, pharmacokinetics (PK) and pharmacodynamics (PD) of GSK3511294,&#xD;
      administered SC in subjects with mild to moderate asthma maintained on a low-medium daily&#xD;
      dose of inhaled corticosteroids (ICS) or ICS/long acting beta-agonist (LABA), and short&#xD;
      acting beta-agonist (SABA). The subjects will attend a pre-screen visit of up to 12 weeks&#xD;
      before dosing for assessment of blood eosinophils. Eligible subjects with blood eosinophils&#xD;
      &gt;=200 cells per microliter (cells/µL) will undergo a screening period of up to 4 weeks. The&#xD;
      subjects will then be randomized into 5 cohorts. In each cohort, the subjects will be&#xD;
      randomized to receive a single dose of GSK3511294 or placebo in a ratio of 3:1. The follow-up&#xD;
      period will be up to 40 weeks post dose and will be dose-dependent. The scheduled maximum&#xD;
      duration for each subject will be up to 44 weeks including up to 28 days of screening.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">October 17, 2017</start_date>
  <completion_date type="Actual">July 31, 2019</completion_date>
  <primary_completion_date type="Actual">July 31, 2019</primary_completion_date>
  <phase>Phase 1</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <intervention_model_description>This is a multi-center, double-blind study in which subjects will be allocated to five cohorts. The subjects in each cohort will be randomized to receive GSK3511294 and placebo in a ratio of 3:1. In each cohort, dosing will be staggered: one subject will receive GSK3511294 and one subject will receive placebo at least 72 hours before the remaining subjects in that cohort are dosed. The remaining subjects will be dosed if the review of all safety data up to 72 hours after dosing of the first two subjects in each cohort is satisfactory.</intervention_model_description>
    <primary_purpose>Treatment</primary_purpose>
    <masking>Double (Participant, Investigator)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Number of Participants With Adverse Events (AEs) and Serious AEs (SAE)</measure>
    <time_frame>Up to Week 40</time_frame>
    <description>An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of a study intervention, whether or not considered related to the study intervention. An SAE is defined as any untoward medical occurrence that, at any dose: results in death; is life-threatening; requires inpatient hospitalization or prolongation of existing hospitalization; results in persistent disability/incapacity; is a congenital anomaly/birth defect; other important medical events that may jeopardize the participant or may require medical or surgical intervention to prevent one of the other outcomes listed before; is associated with liver injury and impaired liver function.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Number of Participants With Adverse Events of Special Interest (AESI)</measure>
    <time_frame>Up to Week 40</time_frame>
    <description>AESIs were defined as Hypersensitivity (narrow) and Injection site reactions like hematoma and swelling.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Neutrophil, Lymphocyte, Monocyte, Eosinophil, Basophil and Platelet Count</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like platelet count, neutrophils, lymphocytes, monocytes, eosinophils and basophils. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Red Blood Cell Count (RBC)</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like RBC count. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Mean Corpuscle Volume (MCV)</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like MCV. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Mean Corpuscle Hemoglobin (MCH)</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like MCH. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Hemoglobin</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like hemoglobin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Hematocrit</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like hematocrit. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Clinical Chemistry Parameter: High Sensitivity C-reactive Protein (hsCRP)</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like hsCRP. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Clinical Chemistry Parameter of Total Protein and Albumin</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like total protein and albumin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Clinical Chemistry Parameters Like Total Bilirubin, Direct Bilirubin and Creatinine</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like total bilirubin, direct bilirubin and creatinine. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Urine Specific Gravity Analysis by Dipstick Method</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Urinary specific gravity measurement is a routine part of urinalysis. Urine specific gravity is a measure of the concentration of solutes in the urine and provides information on the kidney's ability to concentrate urine. The concentration of the excreted molecules determines the urine's specific gravity.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP)</measure>
    <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>SBP and DBP were assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Temperature</measure>
    <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Temperature was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Heart Rate</measure>
    <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Heart rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Respiration Rate</measure>
    <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Respiration rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Heart Rate: Electrocardiogram (ECG)</measure>
    <time_frame>Baseline and at 2 and 8 hours on Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>12-lead ECG were performed in a supine position using an automated ECG machine that calculated the heart rate and measured PR, QRS, QT and corrected QT (QTc) intervals. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in PR Interval, QRS Interval, QT Interval and QT Interval Corrected by Fridericia's Formula (QTcF) Interval</measure>
    <time_frame>Baseline and at 2 and 8 hours on Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>12-lead ECG were performed in a supine position using an automated ECG machine that calculated PR interval, QRS interval, QT interval and QTcF interval. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Clinical Chemistry Parameters Like Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), and Aspartate Aminotransferase (AST)</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like ALP, AST and ALT. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Change From Baseline in Clinical Chemistry Parameter Like Glucose, Calcium, Potassium, Sodium, Blood Urea Nitrogen (BUN), and Magnesium</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like glucose, calcium, potassium, sodium, BUN, and magnesium. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Number of Participants With Presence of Ketones, Glucose, Occult Blood, and Protein</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Urine samples were collected to analyze presence of ketones, occult blood, glucose, and protein in urine. In this dipstick test, the level of occult blood, glucose, ketones and urine protein in urine samples were recorded as negative, trace, 1+ and 2+ indicating proportional concentrations in urine. Only categories with abnormal significant values have been presented.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Urine Potential of Hydrogen (pH) Analysis by Dipstick Method</measure>
    <time_frame>Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Urinary pH measurement is a routine part of urinalysis. Urine pH is an acid-base measurement. pH is measured on a numeric scale ranging from 0 to 14; values on the scale refer to the degree of alkalinity or acidity. A pH of 7 is neutral. A pH less than 7 is acidic, and a pH greater than 7 is basic. Normal urine has a slightly acid pH (5.0 - 6.0).</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Absolute Values of Complement (C)3 and C4</measure>
    <time_frame>Baseline and at Days 2, 3, 4 and 5; Weeks 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
    <description>Blood samples were collected at indicated timepoints for analysis for complement (C3 and C4). Baseline was defined as latest pre-dose assessment with a non-missing value.</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Area Under the Curve From Time Zero to Infinity (AUC[0-inf]) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis. Pharmacokinetic Population included participants in the Safety population for whom a pharmcokinetic sample was obtained and analyzed.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>AUC(0-inf) of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>AUC(0-inf) of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Area Under the Curve From Time Zero to the Last Measurable Concentration (AUC[0-t]) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>AUC(0-t) of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>AUC(0-t) of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Area Under the Concentration-time Curve From Time Zero to Week 4 (AUC[0-Week 4]) of GSK3511294</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, and 4 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 4). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Area Under the Concentration-time Curve From Time Zero to Week 12 (AUC[0-Week 12]) of GSK3511294</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8 and 12 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 12). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Area Under the Concentration-time Curve From Time Zero to Week 26 (AUC [0-Week 26]) of GSK3511294</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24 and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 26). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Percentage of AUC (0-inf) Obtained by Extrapolation (%AUCex) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>%AUCex of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>%AUCex of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Maximum Observed Concentration (Cmax) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Cmax of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Cmax of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time of Occurrence of Cmax (Tmax) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Tmax of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Tmax of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time of Last Quantifiable Concentration (Tlast) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Tlast of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Tlast of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Apparent Clearance Following Subcutaneous Dosing (CL/F) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>CL/F of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>CL/F of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Apparent Volume of Distribution After Subcutaneous Administration (Vd/F) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by terminal elimination rate constant (lambda_z) *AUC(0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Vd/F of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Vd/F of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Terminal Phase Elimination Rate Constant (Lambda_z) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Lambda_z of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Lambda_z of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Terminal Phase Half-life (t1/2) of GSK3511294 2 mg and 10 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>T1/2 of GSK3511294 30 mg and 100 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>T1/2 of GSK3511294 300 mg</measure>
    <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
    <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Ratio to Baseline in Absolute Blood Eosinophil Count</measure>
    <time_frame>Baseline, Days 2, 3, 4, 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36, and 40</time_frame>
    <description>Blood samples were collected at indicated time-points. Analysis was performed using a mixed model repeated measures analysis (MMRM) model on log-transformed data with fixed categorical effects of treatment, planned timepoint and treatment-by-planned timepoint interaction and fixed continuous covariates of log Baseline blood eosinophil count and log Baseline blood eosinophil count-by-planned timepoint interaction. Baseline is defined as the latest predose non-missing blood eosinophil count. Ratio to Baseline is defined as post-dose visit value divided by Baseline value. Pharmacodynamic Population included participants in the 'Safety' population for whom a post-dose pharmacodynamic (ie blood eosinophil) sample was obtained and analyzed.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Number of Participants With Anti-drug Antibody (ADA) Binding to GSK3511294</measure>
    <time_frame>Up to Week 40</time_frame>
    <description>Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. The results were categorized as negative, transient positive (defined as a single confirmatory positive immunogenic response that does not occur at the final study assessment) and persistent positive (defined as a confirmatory positive immunogenic response for at least 2 consecutive assessments or a single result at the final study assessment).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Titers of Binding ADA to GSK3511294</measure>
    <time_frame>Up to Week 40</time_frame>
    <description>Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. Titer was only measured when a positive result was found.</description>
  </secondary_outcome>
  <number_of_arms>10</number_of_arms>
  <enrollment type="Actual">50</enrollment>
  <condition>Asthma</condition>
  <arm_group>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 1</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Six subjects in Cohort 1 will receive a single SC dose of 2 mg GSK3511294.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving placebo in Cohort 1</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Two subjects in Cohort 1 will receive a single SC dose of placebo.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 2</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Six subjects in Cohort 2 will receive a single SC dose of 10 mg GSK3511294.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving placebo in Cohort 2</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Two subjects in Cohort 2 will receive a single SC dose of placebo.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 3</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Nine subjects in Cohort 3 will receive a single SC dose of 30 mg GSK3511294.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving placebo in Cohort 3</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Three subjects in Cohort 3 will receive a single SC dose of placebo.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 4</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Nine subjects in Cohort 4 will receive a single SC dose of 100 mg GSK3511294.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving placebo in Cohort 4</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Three subjects in Cohort 4 will receive a single SC dose of placebo.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 5</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Six subjects in Cohort 5 will receive a single SC dose of 300 mg GSK3511294.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Subjects receiving placebo in Cohort 5</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Two subjects in Cohort 5 will receive a single SC dose of placebo.</description>
  </arm_group>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>GSK3511294</intervention_name>
    <description>GSK3511294 will be available as a clear or opalescent, colorless or yellow to brown solution for injection at unit dose strength of 150 milligrams per milliliter (mg/mL). GSK3511294 will be diluted in 0.9% weight by volume (w/v) sodium chloride to achieve the desired concentration for administration. GSK3511294 will be administered by SC injection.</description>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 1</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 2</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 3</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 4</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 5</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Placebo</intervention_name>
    <description>Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.</description>
    <arm_group_label>Subjects receiving placebo in Cohort 1</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 2</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 3</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 4</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 5</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Salbutamol/albuterol</intervention_name>
    <description>Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.</description>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 1</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 2</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 3</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 4</arm_group_label>
    <arm_group_label>Subjects receiving GSK3511294 in Cohort 5</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 1</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 2</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 3</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 4</arm_group_label>
    <arm_group_label>Subjects receiving placebo in Cohort 5</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Subjects should be between 18 and 65 years of age inclusive, at the time of signing&#xD;
             the informed consent.&#xD;
&#xD;
          -  Blood eosinophils of &gt;= 200 cells/µL at screening.&#xD;
&#xD;
          -  A physician diagnosis of asthma (mild or moderate, as defined by the Global Initiative&#xD;
             for Asthma [GINA], 2017) at least 12 months prior to the start of the study. The&#xD;
             reason for diagnosis of asthma should be documented in the subject's source data,&#xD;
             including relevant history and investigations - specifically evidence of airway&#xD;
             hyper-responsiveness, airflow variation (peak flow rate or forced expiratory volume in&#xD;
             one second [FEV1]) or reversible airflow obstruction should also be documented in the&#xD;
             subject's source data.&#xD;
&#xD;
          -  A screening pre-bronchodilator FEV1 &gt;= 60% of predicted normal value.&#xD;
&#xD;
          -  Asthma Control Test score &gt; 19.&#xD;
&#xD;
          -  hsCRP of &lt; 10 milligrams per liter (mg/L) at screening.&#xD;
&#xD;
          -  Otherwise healthy (other than the acceptable conditions of asthma and other atopic&#xD;
             diseases, including allergic rhinitis and atopic dermatitis) based on a screening&#xD;
             medical history, physical examination, vital signs, ECG assessment, pulmonary function&#xD;
             testing, and clinical laboratory results.&#xD;
&#xD;
          -  Maintained controlled on as needed SABA and one of the following: a) stable dose of&#xD;
             ICS; b) stable dose of combination therapy: ICS/LABA.&#xD;
&#xD;
          -  Body weight &gt;= 50 kilograms (kg), and body mass index (BMI) of 19-32 kilograms per&#xD;
             square meter (kg/m^2) inclusive.&#xD;
&#xD;
          -  Male and female subjects. a) a female subject is eligible to participate if she is not&#xD;
             pregnant, not breastfeeding, and not a woman of childbearing potential. b) as&#xD;
             GSK3511294 is a monoclonal antibody that is not anticipated to interact directly with&#xD;
             Deoxyribonucleic acid (DNA) or other chromosomal material with minimal exposure&#xD;
             through semen expected, male subjects will not be required to use contraception during&#xD;
             the study, nor are they prohibited from donating sperm.&#xD;
&#xD;
          -  Capable of giving signed informed consent, which includes compliance with the&#xD;
             requirements and restrictions of the study.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Any asthma exacerbation requiring systemic corticosteroids within 12 weeks of&#xD;
             screening, or that resulted in overnight hospitalization requiring additional&#xD;
             treatment for asthma within 6 months prior to screening.&#xD;
&#xD;
          -  A history of life-threatening asthma defined as an asthma episode that required&#xD;
             intubation and/or was associated with hypercapnia, respiratory arrest or hypoxic&#xD;
             seizures within the last 5 years.&#xD;
&#xD;
          -  Significant pulmonary diseases, other than asthma, including (but not limited to):&#xD;
             pneumonia previously requiring hospital admission, pulmonary fibrosis,&#xD;
             bronchopulmonary dysplasia, chronic bronchitis, emphysema, chronic obstructive&#xD;
             pulmonary disease, or other significant respiratory abnormalities.&#xD;
&#xD;
          -  Suspected or confirmed bacterial or viral infection (including tuberculosis) of the&#xD;
             upper or lower respiratory tract, sinus or middle ear that occurred within and/or has&#xD;
             not resolved within 4 weeks of screening that: led to a change in asthma management or&#xD;
             in the opinion of the Investigator, is expected to affect the subject's asthma status&#xD;
             or the subject's ability to participate in the study.&#xD;
&#xD;
          -  Positive for hepatitis B surface antigen (HBsAg) at screening.&#xD;
&#xD;
          -  Positive hepatitis C antibody test result at screening, or within 3 months prior to&#xD;
             first dose of study treatment.&#xD;
&#xD;
          -  Known immunodeficiency (other than that explained by the use of corticosteroids),&#xD;
             including a positive test for human immunodeficiency virus (HIV) antibody at&#xD;
             screening.&#xD;
&#xD;
          -  Latent or chronic infections (example, genital herpes, urinary tract infections) or at&#xD;
             risk of infection (example, significant trauma or infection within the 90 days before&#xD;
             screening).&#xD;
&#xD;
          -  Opportunistic infection within 6 months prior to screening (example, a non-tuberculous&#xD;
             mycobacterial infection or cytomegalovirus, pneumocystosis, aspergillosis).&#xD;
&#xD;
          -  Parasitic infestation within 6 months prior to screening, or have travelled to a&#xD;
             country with a high prevalence of such infections in the 6 months before screening, or&#xD;
             intend to do so in the year after dosing.&#xD;
&#xD;
          -  Live vaccine within 4 weeks prior to screening, or intention to receive live vaccine&#xD;
             during the study.&#xD;
&#xD;
          -  Corrected QT by Fridericia's formula (QTcF) interval &gt; 450 milliseconds (msec)&#xD;
&#xD;
          -  A personal history of severe hypertension, arrhythmia, Right Bundle Branch Block, or&#xD;
             Left Bundle Branch Block, or a family history of sudden unexplained death, long QT,&#xD;
             familial cardiac syndrome, or cardiomyopathy.&#xD;
&#xD;
          -  ALT &gt;1.5 times upper limit of normal (ULN).&#xD;
&#xD;
          -  Bilirubin &gt;1.5 times ULN. Isolated bilirubin &gt;1.5 times ULN is acceptable if bilirubin&#xD;
             is fractionated and direct bilirubin &lt;35%.&#xD;
&#xD;
          -  Current or chronic history of liver disease, or known hepatic or biliary abnormalities&#xD;
             (with the exception of Gilbert's syndrome or asymptomatic gallstones).&#xD;
&#xD;
          -  Any history or presence of clinically relevant cardiac or cardiovascular,&#xD;
             gastrointestinal, hepatic, renal, metabolic, hematological, neurological,&#xD;
             osteomuscular, articular, psychiatric, systemic, ocular, or infectious disease or&#xD;
             immunodeficiency, or signs of acute illness, or any other illness or condition that,&#xD;
             in the opinion of the investigator (in consultation with the medical monitor), would&#xD;
             adversely affect the subject's participation in this study.&#xD;
&#xD;
          -  A previous history of cancer in remission for less than 5 years prior to screening&#xD;
             (except for localized carcinoma of the skin that had been resected for cure) or&#xD;
             current malignancy.&#xD;
&#xD;
          -  A positive drug/alcohol test before dosing, OR any history of drug abuse OR regular&#xD;
             alcohol consumption within 6 months of the study defined as: An average weekly intake&#xD;
             of &gt; 14 units alcohol. One unit is equivalent to 8 grams (g) of alcohol: a half-pint&#xD;
             (equivalent to 240 milliliters [mL]) of beer, 1 glass (125 mL) of wine or 1 (25 mL)&#xD;
             measure of spirits.&#xD;
&#xD;
          -  Current smokers or ex-smokers who have given up smoking for &lt; 12 months and/or have a&#xD;
             smoking pack history of &gt; 5 pack years (1 pack year = 20 cigarettes per day for 1 year&#xD;
             or 5 cigarettes per day for 4 years).&#xD;
&#xD;
          -  Urinary cotinine levels indicative of smoking or history or regular use of tobacco- or&#xD;
             nicotine-containing products within 6 months prior to screening.&#xD;
&#xD;
          -  Anticipated non-availability and/or risk of non-compliance with study visits and&#xD;
             procedures, or unwillingness or inability to follow the study specific procedures.&#xD;
&#xD;
          -  The subject has participated in a clinical trial and has received an investigational&#xD;
             product within the following time period prior to the first dosing day in the current&#xD;
             study: 3 months, 5 half-lives or twice the duration of the biological effect of the&#xD;
             investigational product (whichever is longer).&#xD;
&#xD;
          -  Exposure to more than 4 investigational medicinal products within 12 months prior to&#xD;
             the first dosing day.&#xD;
&#xD;
          -  History of sensitivity to any of the study medications, or its components, or a&#xD;
             history of drug reaction or other allergy that, in the opinion of the investigator or&#xD;
             Medical Monitor, contraindicates their participation.&#xD;
&#xD;
          -  Major surgery within 90 days prior to screening, or planned in-patient surgery or&#xD;
             hospitalization during the study period&#xD;
&#xD;
          -  Donation or loss of blood or blood products in excess of 500 mL within the 3 months&#xD;
             before dosing.&#xD;
&#xD;
          -  History of renal disease, abnormal kidney function or evidence of persisting or&#xD;
             clinically relevant protein or blood on urinalysis.&#xD;
&#xD;
          -  History or signs of immunologically active disease (including the presence of low C3&#xD;
             or low C4) or thrombocytopenia.&#xD;
&#xD;
          -  History of vasculitis.&#xD;
&#xD;
          -  Subjects are excluded if they are undergoing desensitization therapy, or have received&#xD;
             any of the following medications as indicated prior to screening: anti- Immunoglobulin&#xD;
             E (IgE) therapy (within 6 months); anti-IL5 (within 6 months); oral or injectable&#xD;
             corticosteroids (within 8 weeks); long acting muscarinic antagonist (LAMA) or&#xD;
             leukotriene receptor antagonist (LTRA) therapy (within 8 weeks); drugs that can&#xD;
             prolong the QT interval.&#xD;
&#xD;
          -  Subjects who are employees of the sponsor or clinical unit are excluded.&#xD;
&#xD;
          -  Vulnerable subjects, e.g., participants kept in detention, protected adults under&#xD;
             guardianship, trusteeship and soldiers, or participants committed to an institution by&#xD;
             governmental or juridical order.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>65 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>GSK Clinical Trials</last_name>
    <role>Study Director</role>
    <affiliation>GlaxoSmithKline</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>GSK Investigational Site</name>
      <address>
        <city>Hannover</city>
        <state>Niedersachsen</state>
        <zip>30625</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>GSK Investigational Site</name>
      <address>
        <city>Berlin</city>
        <zip>14050</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>GSK Investigational Site</name>
      <address>
        <city>Harrow</city>
        <state>Middlesex</state>
        <zip>HA1 3UJ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>GSK Investigational Site</name>
      <address>
        <city>London</city>
        <zip>NW10 7EW</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>GSK Investigational Site</name>
      <address>
        <city>Manchester</city>
        <zip>M23 9QZ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Germany</country>
    <country>United Kingdom</country>
  </location_countries>
  <verification_date>February 2021</verification_date>
  <study_first_submitted>September 15, 2017</study_first_submitted>
  <study_first_submitted_qc>September 15, 2017</study_first_submitted_qc>
  <study_first_posted type="Actual">September 19, 2017</study_first_posted>
  <results_first_submitted>February 5, 2021</results_first_submitted>
  <results_first_submitted_qc>February 5, 2021</results_first_submitted_qc>
  <results_first_posted type="Actual">March 1, 2021</results_first_posted>
  <last_update_submitted>February 5, 2021</last_update_submitted>
  <last_update_submitted_qc>February 5, 2021</last_update_submitted_qc>
  <last_update_posted type="Actual">March 1, 2021</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <keyword>eosinophils</keyword>
  <keyword>pharmacokinetics</keyword>
  <keyword>First time in Human</keyword>
  <keyword>GSK3511294</keyword>
  <keyword>pharmacodynamics</keyword>
  <keyword>asthma</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Asthma</mesh_term>
  </condition_browse>
  <intervention_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Albuterol</mesh_term>
  </intervention_browse>
  <patient_data>
    <sharing_ipd>Yes</sharing_ipd>
    <ipd_description>IPD for this study will be made available via the Clinical Study Data Request Site</ipd_description>
    <ipd_info_type>Study Protocol</ipd_info_type>
    <ipd_info_type>Statistical Analysis Plan (SAP)</ipd_info_type>
    <ipd_info_type>Informed Consent Form (ICF)</ipd_info_type>
    <ipd_info_type>Clinical Study Report (CSR)</ipd_info_type>
    <ipd_time_frame>IPD will be made available within 6 months of publishing the results of the primary endpoints of the study</ipd_time_frame>
    <ipd_access_criteria>Access is provided after a research proposal is submitted and has received approval from the Independent Review Panel and after a Data Sharing Agreement is in place. Access is provided for an initial period of 12 months but an extension can be granted, when justified, for up to another 12 months.</ipd_access_criteria>
    <ipd_url>http://clinicalstudydatarequest.com</ipd_url>
  </patient_data>
  <provided_document_section>
    <provided_document>
      <document_type>Statistical Analysis Plan</document_type>
      <document_has_protocol>No</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>Yes</document_has_sap>
      <document_date>May 23, 2019</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/10/NCT03287310/SAP_000.pdf</document_url>
    </provided_document>
    <provided_document>
      <document_type>Study Protocol</document_type>
      <document_has_protocol>Yes</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>No</document_has_sap>
      <document_date>January 7, 2019</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/10/NCT03287310/Prot_001.pdf</document_url>
    </provided_document>
  </provided_document_section>

  <clinical_results>

    <participant_flow>
      <recruitment_details>This was double-blind, placebo-controlled, single ascending dose study in participants with mild to moderate asthma to assess safety, tolerability, immunogenicity, pharmacokinetics and pharmcodynamics of GSK3511294 administered subcutaneously. The study was conducted in Germany and United Kingdom.</recruitment_details>
      <pre_assignment_details>A total of 50 participants were enrolled in this study, of which two did not receive any study treatment and 48 were included in the Safety Population.</pre_assignment_details>
      <group_list>
        <group group_id="P1">
          <title>Placebo</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
        </group>
        <group group_id="P2">
          <title>GSK3511294 2 mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
        </group>
        <group group_id="P3">
          <title>GSK3511294 10 mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
        </group>
        <group group_id="P4">
          <title>GSK3511294 30 mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
        </group>
        <group group_id="P5">
          <title>GSK3511294 100 mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
        </group>
        <group group_id="P6">
          <title>GSK3511294 300 mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
        </group>
      </group_list>
      <period_list>
        <period>
          <title>Overall Study</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="12"/>
                <participants group_id="P2" count="6"/>
                <participants group_id="P3" count="6"/>
                <participants group_id="P4" count="9"/>
                <participants group_id="P5" count="9"/>
                <participants group_id="P6" count="6"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="12"/>
                <participants group_id="P2" count="6"/>
                <participants group_id="P3" count="6"/>
                <participants group_id="P4" count="9"/>
                <participants group_id="P5" count="9"/>
                <participants group_id="P6" count="6"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
              </participants_list>
            </milestone>
          </milestone_list>
        </period>
      </period_list>
    </participant_flow>

    <baseline>
      <group_list>
        <group group_id="B1">
          <title>Placebo</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
        </group>
        <group group_id="B2">
          <title>GSK3511294 2mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
        </group>
        <group group_id="B3">
          <title>GSK3511294 10mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
        </group>
        <group group_id="B4">
          <title>GSK3511294 30mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
        </group>
        <group group_id="B5">
          <title>GSK3511294 100mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
        </group>
        <group group_id="B6">
          <title>GSK3511294 300mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
        </group>
        <group group_id="B7">
          <title>Total</title>
          <description>Total of all reporting groups</description>
        </group>
      </group_list>
      <analyzed_list>
        <analyzed>
          <units>Participants</units>
          <scope>Overall</scope>
          <count_list>
            <count group_id="B1" value="12"/>
            <count group_id="B2" value="6"/>
            <count group_id="B3" value="6"/>
            <count group_id="B4" value="9"/>
            <count group_id="B5" value="9"/>
            <count group_id="B6" value="6"/>
            <count group_id="B7" value="48"/>
          </count_list>
        </analyzed>
      </analyzed_list>
      <measure_list>
        <measure>
          <title>Age</title>
          <units>years</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="44.0" spread="13.37"/>
                    <measurement group_id="B2" value="43.5" spread="10.71"/>
                    <measurement group_id="B3" value="44.7" spread="13.20"/>
                    <measurement group_id="B4" value="44.9" spread="10.23"/>
                    <measurement group_id="B5" value="42.0" spread="10.84"/>
                    <measurement group_id="B6" value="45.2" spread="11.18"/>
                    <measurement group_id="B7" value="44.0" spread="11.17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Sex: Female, Male</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <category_list>
                <category>
                  <title>Female</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="1"/>
                    <measurement group_id="B6" value="1"/>
                    <measurement group_id="B7" value="2"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Male</title>
                  <measurement_list>
                    <measurement group_id="B1" value="12"/>
                    <measurement group_id="B2" value="6"/>
                    <measurement group_id="B3" value="6"/>
                    <measurement group_id="B4" value="9"/>
                    <measurement group_id="B5" value="8"/>
                    <measurement group_id="B6" value="5"/>
                    <measurement group_id="B7" value="46"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Race/Ethnicity, Customized</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <title>Central/South Asian Heritage</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="1"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="1"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Black or African American (Afr. Amer.)</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="1"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="1"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Arabic/North African Heritage</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="1"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>White/Caucasian/European Heritage</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="9"/>
                    <measurement group_id="B2" value="5"/>
                    <measurement group_id="B3" value="6"/>
                    <measurement group_id="B4" value="7"/>
                    <measurement group_id="B5" value="9"/>
                    <measurement group_id="B6" value="6"/>
                    <measurement group_id="B7" value="42"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Black/Afr. Amer./White/Caucasian/European Heritage</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="1"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </measure_list>
    </baseline>

    <outcome_list>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Adverse Events (AEs) and Serious AEs (SAE)</title>
        <description>An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of a study intervention, whether or not considered related to the study intervention. An SAE is defined as any untoward medical occurrence that, at any dose: results in death; is life-threatening; requires inpatient hospitalization or prolongation of existing hospitalization; results in persistent disability/incapacity; is a congenital anomaly/birth defect; other important medical events that may jeopardize the participant or may require medical or surgical intervention to prevent one of the other outcomes listed before; is associated with liver injury and impaired liver function.</description>
        <time_frame>Up to Week 40</time_frame>
        <population>Safety Population comprised of all randomized participants who received at least one dose of the study treatment.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Adverse Events (AEs) and Serious AEs (SAE)</title>
          <description>An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of a study intervention, whether or not considered related to the study intervention. An SAE is defined as any untoward medical occurrence that, at any dose: results in death; is life-threatening; requires inpatient hospitalization or prolongation of existing hospitalization; results in persistent disability/incapacity; is a congenital anomaly/birth defect; other important medical events that may jeopardize the participant or may require medical or surgical intervention to prevent one of the other outcomes listed before; is associated with liver injury and impaired liver function.</description>
          <population>Safety Population comprised of all randomized participants who received at least one dose of the study treatment.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Any AE</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="11"/>
                    <measurement group_id="O2" value="2"/>
                    <measurement group_id="O3" value="6"/>
                    <measurement group_id="O4" value="8"/>
                    <measurement group_id="O5" value="9"/>
                    <measurement group_id="O6" value="4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Any SAE</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Adverse Events of Special Interest (AESI)</title>
        <description>AESIs were defined as Hypersensitivity (narrow) and Injection site reactions like hematoma and swelling.</description>
        <time_frame>Up to Week 40</time_frame>
        <population>Safety Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Adverse Events of Special Interest (AESI)</title>
          <description>AESIs were defined as Hypersensitivity (narrow) and Injection site reactions like hematoma and swelling.</description>
          <population>Safety Population.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Hypersensitivity</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="1"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Injection Site Reaction: hematoma</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Injection Site Reaction: swelling</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Neutrophil, Lymphocyte, Monocyte, Eosinophil, Basophil and Platelet Count</title>
        <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like platelet count, neutrophils, lymphocytes, monocytes, eosinophils and basophils. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Neutrophil, Lymphocyte, Monocyte, Eosinophil, Basophil and Platelet Count</title>
          <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like platelet count, neutrophils, lymphocytes, monocytes, eosinophils and basophils. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Giga cells per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Basophils, Day 2,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.006" spread="0.0247"/>
                    <measurement group_id="O2" value="-0.020" spread="0.0297"/>
                    <measurement group_id="O3" value="0.003" spread="0.0103"/>
                    <measurement group_id="O4" value="-0.003" spread="0.0238"/>
                    <measurement group_id="O5" value="0.001" spread="0.0302"/>
                    <measurement group_id="O6" value="-0.018" spread="0.0160"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0356"/>
                    <measurement group_id="O2" value="0.003" spread="0.0450"/>
                    <measurement group_id="O3" value="0.010" spread="0.0126"/>
                    <measurement group_id="O4" value="-0.003" spread="0.0260"/>
                    <measurement group_id="O5" value="-0.003" spread="0.0224"/>
                    <measurement group_id="O6" value="-0.007" spread="0.0121"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.003" spread="0.0296"/>
                    <measurement group_id="O2" value="0.002" spread="0.0214"/>
                    <measurement group_id="O3" value="-0.008" spread="0.0325"/>
                    <measurement group_id="O4" value="-0.004" spread="0.0207"/>
                    <measurement group_id="O5" value="-0.001" spread="0.0136"/>
                    <measurement group_id="O6" value="0.002" spread="0.0214"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Day 5,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.020" spread="0.0224"/>
                    <measurement group_id="O2" value="-0.008" spread="0.0204"/>
                    <measurement group_id="O3" value="-0.020" spread="0.0141"/>
                    <measurement group_id="O4" value="-0.009" spread="0.0196"/>
                    <measurement group_id="O5" value="-0.003" spread="0.0255"/>
                    <measurement group_id="O6" value="-0.025" spread="0.0164"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.001" spread="0.0257"/>
                    <measurement group_id="O2" value="-0.017" spread="0.0207"/>
                    <measurement group_id="O3" value="-0.018" spread="0.0306"/>
                    <measurement group_id="O4" value="0.002" spread="0.0291"/>
                    <measurement group_id="O5" value="0.001" spread="0.0162"/>
                    <measurement group_id="O6" value="-0.006" spread="0.0055"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.006" spread="0.0215"/>
                    <measurement group_id="O2" value="-0.018" spread="0.0204"/>
                    <measurement group_id="O3" value="0.000" spread="0.0274"/>
                    <measurement group_id="O4" value="-0.004" spread="0.0224"/>
                    <measurement group_id="O5" value="-0.007" spread="0.0158"/>
                    <measurement group_id="O6" value="-0.007" spread="0.0137"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.0316"/>
                    <measurement group_id="O2" value="-0.002" spread="0.0232"/>
                    <measurement group_id="O3" value="-0.004" spread="0.0167"/>
                    <measurement group_id="O4" value="0.002" spread="0.0172"/>
                    <measurement group_id="O5" value="-0.006" spread="0.0265"/>
                    <measurement group_id="O6" value="-0.010" spread="0.0126"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.005" spread="0.0183"/>
                    <measurement group_id="O2" value="0.007" spread="0.0266"/>
                    <measurement group_id="O3" value="-0.022" spread="0.0271"/>
                    <measurement group_id="O4" value="-0.010" spread="0.0122"/>
                    <measurement group_id="O5" value="-0.002" spread="0.0186"/>
                    <measurement group_id="O6" value="-0.015" spread="0.0138"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 12,n=12,5,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0229"/>
                    <measurement group_id="O2" value="-0.014" spread="0.0297"/>
                    <measurement group_id="O3" value="-0.008" spread="0.0147"/>
                    <measurement group_id="O4" value="-0.003" spread="0.0245"/>
                    <measurement group_id="O5" value="-0.004" spread="0.0142"/>
                    <measurement group_id="O6" value="-0.006" spread="0.0055"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.002" spread="0.0229"/>
                    <measurement group_id="O2" value="0.010" spread="0.0310"/>
                    <measurement group_id="O3" value="-0.012" spread="0.0160"/>
                    <measurement group_id="O4" value="-0.001" spread="0.0267"/>
                    <measurement group_id="O5" value="0.010" spread="0.0278"/>
                    <measurement group_id="O6" value="-0.005" spread="0.0105"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.005" spread="0.0157"/>
                    <measurement group_id="O2" value="0.002" spread="0.0264"/>
                    <measurement group_id="O3" value="-0.005" spread="0.0288"/>
                    <measurement group_id="O4" value="-0.004" spread="0.0313"/>
                    <measurement group_id="O5" value="-0.001" spread="0.0154"/>
                    <measurement group_id="O6" value="-0.018" spread="0.0117"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.0284"/>
                    <measurement group_id="O2" value="0.002" spread="0.0306"/>
                    <measurement group_id="O3" value="0.000" spread="0.0219"/>
                    <measurement group_id="O4" value="0.008" spread="0.0383"/>
                    <measurement group_id="O5" value="-0.002" spread="0.0199"/>
                    <measurement group_id="O6" value="-0.008" spread="0.0133"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.002" spread="0.0376"/>
                    <measurement group_id="O2" value="0.010" spread="0.0210"/>
                    <measurement group_id="O3" value="0.005" spread="0.0339"/>
                    <measurement group_id="O6" value="-0.008" spread="0.0117"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.002" spread="0.0214"/>
                    <measurement group_id="O4" value="0.021" spread="0.0247"/>
                    <measurement group_id="O5" value="-0.002" spread="0.0199"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O6" value="-0.012" spread="0.0313"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Day 2,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.024" spread="0.1412"/>
                    <measurement group_id="O2" value="-0.120" spread="0.0587"/>
                    <measurement group_id="O3" value="-0.145" spread="0.0797"/>
                    <measurement group_id="O4" value="-0.251" spread="0.1504"/>
                    <measurement group_id="O5" value="-0.208" spread="0.1685"/>
                    <measurement group_id="O6" value="-0.152" spread="0.0794"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.001" spread="0.1986"/>
                    <measurement group_id="O2" value="-0.167" spread="0.0755"/>
                    <measurement group_id="O3" value="-0.203" spread="0.0876"/>
                    <measurement group_id="O4" value="-0.289" spread="0.0987"/>
                    <measurement group_id="O5" value="-0.287" spread="0.1744"/>
                    <measurement group_id="O6" value="-0.182" spread="0.0920"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.014" spread="0.1950"/>
                    <measurement group_id="O2" value="-0.172" spread="0.0749"/>
                    <measurement group_id="O3" value="-0.212" spread="0.1144"/>
                    <measurement group_id="O4" value="-0.348" spread="0.1149"/>
                    <measurement group_id="O5" value="-0.300" spread="0.1829"/>
                    <measurement group_id="O6" value="-0.192" spread="0.0643"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Day 5,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.034" spread="0.1529"/>
                    <measurement group_id="O2" value="-0.202" spread="0.0799"/>
                    <measurement group_id="O3" value="-0.235" spread="0.1117"/>
                    <measurement group_id="O4" value="-0.326" spread="0.1385"/>
                    <measurement group_id="O5" value="-0.276" spread="0.1351"/>
                    <measurement group_id="O6" value="-0.210" spread="0.0767"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.033" spread="0.1461"/>
                    <measurement group_id="O2" value="-0.195" spread="0.0609"/>
                    <measurement group_id="O3" value="-0.242" spread="0.1189"/>
                    <measurement group_id="O4" value="-0.324" spread="0.1350"/>
                    <measurement group_id="O5" value="-0.298" spread="0.1824"/>
                    <measurement group_id="O6" value="-0.206" spread="0.0568"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.072" spread="0.1809"/>
                    <measurement group_id="O2" value="-0.212" spread="0.0895"/>
                    <measurement group_id="O3" value="-0.210" spread="0.0886"/>
                    <measurement group_id="O4" value="-0.344" spread="0.1334"/>
                    <measurement group_id="O5" value="-0.307" spread="0.1602"/>
                    <measurement group_id="O6" value="-0.223" spread="0.0952"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.025" spread="0.1635"/>
                    <measurement group_id="O2" value="-0.227" spread="0.0712"/>
                    <measurement group_id="O3" value="-0.238" spread="0.1150"/>
                    <measurement group_id="O4" value="-0.366" spread="0.1466"/>
                    <measurement group_id="O5" value="-0.321" spread="0.1969"/>
                    <measurement group_id="O6" value="-0.253" spread="0.0855"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.036" spread="0.1486"/>
                    <measurement group_id="O2" value="-0.230" spread="0.0769"/>
                    <measurement group_id="O3" value="-0.280" spread="0.1202"/>
                    <measurement group_id="O4" value="-0.379" spread="0.1519"/>
                    <measurement group_id="O5" value="-0.343" spread="0.1841"/>
                    <measurement group_id="O6" value="-0.252" spread="0.1007"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 12,n=12,5,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.025" spread="0.1566"/>
                    <measurement group_id="O2" value="-0.174" spread="0.0777"/>
                    <measurement group_id="O3" value="-0.262" spread="0.1087"/>
                    <measurement group_id="O4" value="-0.371" spread="0.1484"/>
                    <measurement group_id="O5" value="-0.336" spread="0.1895"/>
                    <measurement group_id="O6" value="-0.250" spread="0.1245"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.029" spread="0.1263"/>
                    <measurement group_id="O2" value="-0.148" spread="0.0685"/>
                    <measurement group_id="O3" value="-0.208" spread="0.1153"/>
                    <measurement group_id="O4" value="-0.359" spread="0.1445"/>
                    <measurement group_id="O5" value="-0.338" spread="0.1786"/>
                    <measurement group_id="O6" value="-0.253" spread="0.1067"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.021" spread="0.1436"/>
                    <measurement group_id="O2" value="-0.072" spread="0.0662"/>
                    <measurement group_id="O3" value="-0.103" spread="0.1916"/>
                    <measurement group_id="O4" value="-0.300" spread="0.1546"/>
                    <measurement group_id="O5" value="-0.334" spread="0.1769"/>
                    <measurement group_id="O6" value="-0.245" spread="0.1017"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.035" spread="0.1812"/>
                    <measurement group_id="O2" value="-0.042" spread="0.0571"/>
                    <measurement group_id="O3" value="-0.037" spread="0.2813"/>
                    <measurement group_id="O4" value="-0.273" spread="0.1773"/>
                    <measurement group_id="O5" value="-0.319" spread="0.1724"/>
                    <measurement group_id="O6" value="-0.252" spread="0.0920"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.008" spread="0.0935"/>
                    <measurement group_id="O2" value="0.042" spread="0.1153"/>
                    <measurement group_id="O3" value="0.003" spread="0.2467"/>
                    <measurement group_id="O6" value="-0.235" spread="0.1205"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.045" spread="0.1758"/>
                    <measurement group_id="O4" value="-0.041" spread="0.2734"/>
                    <measurement group_id="O5" value="-0.258" spread="0.1594"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.245" spread="0.1344"/>
                    <measurement group_id="O6" value="-0.222" spread="0.1196"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Day 2,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.3897"/>
                    <measurement group_id="O2" value="0.135" spread="0.2886"/>
                    <measurement group_id="O3" value="0.108" spread="0.2185"/>
                    <measurement group_id="O4" value="-0.061" spread="0.3165"/>
                    <measurement group_id="O5" value="-0.157" spread="0.3336"/>
                    <measurement group_id="O6" value="0.100" spread="0.2804"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.064" spread="0.4447"/>
                    <measurement group_id="O2" value="0.330" spread="0.3571"/>
                    <measurement group_id="O3" value="0.143" spread="0.1810"/>
                    <measurement group_id="O4" value="-0.140" spread="0.2382"/>
                    <measurement group_id="O5" value="-0.081" spread="0.4131"/>
                    <measurement group_id="O6" value="0.143" spread="0.3296"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.006" spread="0.4963"/>
                    <measurement group_id="O2" value="0.193" spread="0.3242"/>
                    <measurement group_id="O3" value="0.172" spread="0.3474"/>
                    <measurement group_id="O4" value="0.005" spread="0.1753"/>
                    <measurement group_id="O5" value="0.005" spread="0.3798"/>
                    <measurement group_id="O6" value="0.210" spread="0.2772"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Day 5,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.077" spread="0.4746"/>
                    <measurement group_id="O2" value="0.108" spread="0.2319"/>
                    <measurement group_id="O3" value="0.085" spread="0.1302"/>
                    <measurement group_id="O4" value="-0.253" spread="0.2983"/>
                    <measurement group_id="O5" value="0.104" spread="0.4463"/>
                    <measurement group_id="O6" value="0.047" spread="0.1226"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.048" spread="0.4628"/>
                    <measurement group_id="O2" value="0.295" spread="0.2404"/>
                    <measurement group_id="O3" value="0.058" spread="0.4116"/>
                    <measurement group_id="O4" value="-0.060" spread="0.3248"/>
                    <measurement group_id="O5" value="-0.018" spread="0.4217"/>
                    <measurement group_id="O6" value="-0.154" spread="0.2587"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.133" spread="0.4107"/>
                    <measurement group_id="O2" value="0.222" spread="0.3543"/>
                    <measurement group_id="O3" value="0.096" spread="0.4117"/>
                    <measurement group_id="O4" value="-0.120" spread="0.3304"/>
                    <measurement group_id="O5" value="-0.068" spread="0.4104"/>
                    <measurement group_id="O6" value="0.047" spread="0.1189"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.189" spread="0.4616"/>
                    <measurement group_id="O2" value="0.088" spread="0.2938"/>
                    <measurement group_id="O3" value="0.056" spread="0.2899"/>
                    <measurement group_id="O4" value="-0.062" spread="0.2346"/>
                    <measurement group_id="O5" value="-0.052" spread="0.5189"/>
                    <measurement group_id="O6" value="-0.137" spread="0.2103"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.057" spread="0.4665"/>
                    <measurement group_id="O2" value="0.105" spread="0.2670"/>
                    <measurement group_id="O3" value="-0.107" spread="0.3584"/>
                    <measurement group_id="O4" value="-0.188" spread="0.2277"/>
                    <measurement group_id="O5" value="0.052" spread="0.3287"/>
                    <measurement group_id="O6" value="-0.075" spread="0.0672"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 12,n=12,5,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.142" spread="0.4107"/>
                    <measurement group_id="O2" value="0.228" spread="0.1968"/>
                    <measurement group_id="O3" value="0.072" spread="0.4113"/>
                    <measurement group_id="O4" value="0.014" spread="0.2490"/>
                    <measurement group_id="O5" value="0.048" spread="0.3231"/>
                    <measurement group_id="O6" value="-0.388" spread="0.2237"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.212" spread="0.4094"/>
                    <measurement group_id="O2" value="-0.032" spread="0.2213"/>
                    <measurement group_id="O3" value="-0.042" spread="0.3612"/>
                    <measurement group_id="O4" value="-0.097" spread="0.4088"/>
                    <measurement group_id="O5" value="0.050" spread="0.4539"/>
                    <measurement group_id="O6" value="-0.063" spread="0.1788"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.179" spread="0.3876"/>
                    <measurement group_id="O2" value="-0.028" spread="0.3616"/>
                    <measurement group_id="O3" value="-0.040" spread="0.2744"/>
                    <measurement group_id="O4" value="-0.070" spread="0.3102"/>
                    <measurement group_id="O5" value="0.052" spread="0.9838"/>
                    <measurement group_id="O6" value="-0.132" spread="0.1619"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.088" spread="0.4361"/>
                    <measurement group_id="O2" value="-0.223" spread="0.3808"/>
                    <measurement group_id="O3" value="-0.138" spread="0.3577"/>
                    <measurement group_id="O4" value="-0.116" spread="0.4946"/>
                    <measurement group_id="O5" value="0.018" spread="0.5392"/>
                    <measurement group_id="O6" value="-0.188" spread="0.2566"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.165" spread="0.6851"/>
                    <measurement group_id="O2" value="-0.057" spread="0.2842"/>
                    <measurement group_id="O3" value="-0.197" spread="0.5467"/>
                    <measurement group_id="O6" value="-0.148" spread="0.2017"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.007" spread="0.1838"/>
                    <measurement group_id="O4" value="-0.043" spread="0.4393"/>
                    <measurement group_id="O5" value="0.006" spread="0.4176"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.285" spread="0.3465"/>
                    <measurement group_id="O6" value="-0.125" spread="0.2966"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Day 2,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.002" spread="0.0914"/>
                    <measurement group_id="O2" value="0.017" spread="0.1357"/>
                    <measurement group_id="O3" value="0.123" spread="0.1240"/>
                    <measurement group_id="O4" value="0.015" spread="0.1176"/>
                    <measurement group_id="O5" value="0.019" spread="0.0715"/>
                    <measurement group_id="O6" value="0.052" spread="0.1947"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.029" spread="0.1001"/>
                    <measurement group_id="O2" value="0.028" spread="0.1533"/>
                    <measurement group_id="O3" value="0.100" spread="0.1235"/>
                    <measurement group_id="O4" value="-0.028" spread="0.0753"/>
                    <measurement group_id="O5" value="0.032" spread="0.0952"/>
                    <measurement group_id="O6" value="0.018" spread="0.1514"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.032" spread="0.0936"/>
                    <measurement group_id="O2" value="-0.002" spread="0.1258"/>
                    <measurement group_id="O3" value="0.118" spread="0.1057"/>
                    <measurement group_id="O4" value="-0.038" spread="0.0927"/>
                    <measurement group_id="O5" value="0.068" spread="0.1074"/>
                    <measurement group_id="O6" value="0.050" spread="0.0434"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Day 5,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.034" spread="0.0841"/>
                    <measurement group_id="O2" value="-0.025" spread="0.0701"/>
                    <measurement group_id="O3" value="0.053" spread="0.1299"/>
                    <measurement group_id="O4" value="-0.100" spread="0.1470"/>
                    <measurement group_id="O5" value="0.074" spread="0.1874"/>
                    <measurement group_id="O6" value="-0.035" spread="0.0766"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.006" spread="0.0998"/>
                    <measurement group_id="O2" value="0.072" spread="0.1127"/>
                    <measurement group_id="O3" value="0.057" spread="0.1786"/>
                    <measurement group_id="O4" value="0.032" spread="0.0578"/>
                    <measurement group_id="O5" value="0.101" spread="0.1039"/>
                    <measurement group_id="O6" value="-0.012" spread="0.0926"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.013" spread="0.0945"/>
                    <measurement group_id="O2" value="0.050" spread="0.1621"/>
                    <measurement group_id="O3" value="0.056" spread="0.0451"/>
                    <measurement group_id="O4" value="0.004" spread="0.0975"/>
                    <measurement group_id="O5" value="0.118" spread="0.1738"/>
                    <measurement group_id="O6" value="0.090" spread="0.2697"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.001" spread="0.0757"/>
                    <measurement group_id="O2" value="0.103" spread="0.1382"/>
                    <measurement group_id="O3" value="-0.018" spread="0.0817"/>
                    <measurement group_id="O4" value="0.042" spread="0.0559"/>
                    <measurement group_id="O5" value="0.041" spread="0.1014"/>
                    <measurement group_id="O6" value="-0.003" spread="0.1201"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.048" spread="0.1377"/>
                    <measurement group_id="O2" value="0.123" spread="0.1681"/>
                    <measurement group_id="O3" value="-0.053" spread="0.0484"/>
                    <measurement group_id="O4" value="-0.006" spread="0.0648"/>
                    <measurement group_id="O5" value="0.080" spread="0.1211"/>
                    <measurement group_id="O6" value="0.058" spread="0.1509"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 12,n=12,5,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.007" spread="0.1042"/>
                    <measurement group_id="O2" value="0.050" spread="0.0561"/>
                    <measurement group_id="O3" value="-0.013" spread="0.0841"/>
                    <measurement group_id="O4" value="0.059" spread="0.0864"/>
                    <measurement group_id="O5" value="0.140" spread="0.1734"/>
                    <measurement group_id="O6" value="0.084" spread="0.1680"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.042" spread="0.0897"/>
                    <measurement group_id="O2" value="-0.040" spread="0.1362"/>
                    <measurement group_id="O3" value="-0.045" spread="0.0944"/>
                    <measurement group_id="O4" value="0.018" spread="0.1475"/>
                    <measurement group_id="O5" value="0.092" spread="0.0874"/>
                    <measurement group_id="O6" value="0.043" spread="0.1516"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.028" spread="0.1181"/>
                    <measurement group_id="O2" value="-0.013" spread="0.0989"/>
                    <measurement group_id="O3" value="0.070" spread="0.0921"/>
                    <measurement group_id="O4" value="0.047" spread="0.1301"/>
                    <measurement group_id="O5" value="0.159" spread="0.2567"/>
                    <measurement group_id="O6" value="0.037" spread="0.0975"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.040" spread="0.0888"/>
                    <measurement group_id="O2" value="-0.037" spread="0.1129"/>
                    <measurement group_id="O3" value="0.010" spread="0.0551"/>
                    <measurement group_id="O4" value="0.036" spread="0.1267"/>
                    <measurement group_id="O5" value="0.121" spread="0.1500"/>
                    <measurement group_id="O6" value="0.013" spread="0.0720"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.035" spread="0.0817"/>
                    <measurement group_id="O2" value="-0.013" spread="0.1600"/>
                    <measurement group_id="O3" value="0.098" spread="0.0783"/>
                    <measurement group_id="O6" value="-0.012" spread="0.0662"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.067" spread="0.0717"/>
                    <measurement group_id="O4" value="0.053" spread="0.1624"/>
                    <measurement group_id="O5" value="0.158" spread="0.2126"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.040" spread="0.0566"/>
                    <measurement group_id="O6" value="-0.032" spread="0.0873"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Day 2,n=12,5,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-9.7" spread="19.00"/>
                    <measurement group_id="O2" value="-6.8" spread="10.40"/>
                    <measurement group_id="O3" value="-6.4" spread="15.27"/>
                    <measurement group_id="O4" value="-6.8" spread="17.99"/>
                    <measurement group_id="O5" value="6.1" spread="22.05"/>
                    <measurement group_id="O6" value="-1.5" spread="19.32"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Day 3,n=12,5,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="16.72"/>
                    <measurement group_id="O2" value="-9.4" spread="8.29"/>
                    <measurement group_id="O3" value="5.7" spread="13.00"/>
                    <measurement group_id="O4" value="-7.1" spread="19.98"/>
                    <measurement group_id="O5" value="1.7" spread="19.24"/>
                    <measurement group_id="O6" value="-0.8" spread="19.60"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Day 4,n=12,5,5,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.6" spread="18.64"/>
                    <measurement group_id="O2" value="-5.8" spread="3.63"/>
                    <measurement group_id="O3" value="6.6" spread="15.66"/>
                    <measurement group_id="O4" value="-0.4" spread="18.86"/>
                    <measurement group_id="O5" value="-1.1" spread="21.56"/>
                    <measurement group_id="O6" value="-0.2" spread="6.62"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Day 5,n=12,5,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-7.6" spread="17.59"/>
                    <measurement group_id="O2" value="-3.6" spread="13.89"/>
                    <measurement group_id="O3" value="-3.0" spread="18.11"/>
                    <measurement group_id="O4" value="-4.6" spread="19.09"/>
                    <measurement group_id="O5" value="6.2" spread="22.90"/>
                    <measurement group_id="O6" value="-2.8" spread="18.62"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 1,n=12,5,6,9,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.9" spread="20.21"/>
                    <measurement group_id="O2" value="-10.2" spread="11.30"/>
                    <measurement group_id="O3" value="5.0" spread="21.08"/>
                    <measurement group_id="O4" value="-3.9" spread="12.41"/>
                    <measurement group_id="O5" value="16.8" spread="25.37"/>
                    <measurement group_id="O6" value="-13.8" spread="28.69"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 2,n=12,5,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.5" spread="16.51"/>
                    <measurement group_id="O2" value="2.8" spread="13.59"/>
                    <measurement group_id="O3" value="-6.3" spread="29.38"/>
                    <measurement group_id="O4" value="-0.9" spread="25.09"/>
                    <measurement group_id="O5" value="25.0" spread="38.64"/>
                    <measurement group_id="O6" value="-15.5" spread="39.81"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 4,n=12,5,4,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-11.5" spread="26.10"/>
                    <measurement group_id="O2" value="-6.8" spread="20.93"/>
                    <measurement group_id="O3" value="1.3" spread="37.07"/>
                    <measurement group_id="O4" value="-1.6" spread="17.61"/>
                    <measurement group_id="O5" value="12.3" spread="35.87"/>
                    <measurement group_id="O6" value="-5.0" spread="22.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 8,n=12,5,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.3" spread="22.85"/>
                    <measurement group_id="O2" value="11.6" spread="23.71"/>
                    <measurement group_id="O3" value="2.6" spread="29.01"/>
                    <measurement group_id="O4" value="-11.3" spread="21.03"/>
                    <measurement group_id="O5" value="22.0" spread="30.81"/>
                    <measurement group_id="O6" value="-3.5" spread="23.89"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 12,n=12,5,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-14.8" spread="26.42"/>
                    <measurement group_id="O2" value="-6.0" spread="16.63"/>
                    <measurement group_id="O3" value="-9.0" spread="26.83"/>
                    <measurement group_id="O4" value="-10.8" spread="10.15"/>
                    <measurement group_id="O5" value="27.4" spread="43.23"/>
                    <measurement group_id="O6" value="-25.6" spread="24.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 18,n=12,5,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-8.6" spread="21.65"/>
                    <measurement group_id="O2" value="-13.4" spread="20.42"/>
                    <measurement group_id="O3" value="-14.0" spread="9.53"/>
                    <measurement group_id="O4" value="1.6" spread="19.51"/>
                    <measurement group_id="O5" value="15.9" spread="22.45"/>
                    <measurement group_id="O6" value="2.2" spread="28.92"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 24,n=10,5,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="10"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.9" spread="14.81"/>
                    <measurement group_id="O2" value="-7.8" spread="18.35"/>
                    <measurement group_id="O3" value="-10.0" spread="14.97"/>
                    <measurement group_id="O4" value="-1.6" spread="19.94"/>
                    <measurement group_id="O5" value="19.7" spread="30.07"/>
                    <measurement group_id="O6" value="-5.7" spread="39.38"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 26,n=12,5,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.4" spread="30.14"/>
                    <measurement group_id="O2" value="-13.8" spread="17.70"/>
                    <measurement group_id="O3" value="-19.3" spread="13.81"/>
                    <measurement group_id="O4" value="-2.4" spread="12.21"/>
                    <measurement group_id="O5" value="11.8" spread="36.37"/>
                    <measurement group_id="O6" value="-6.8" spread="17.38"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 32,n=6,5,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.5" spread="18.71"/>
                    <measurement group_id="O2" value="-0.6" spread="15.37"/>
                    <measurement group_id="O3" value="-6.3" spread="10.39"/>
                    <measurement group_id="O6" value="-15.7" spread="51.15"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="25.65"/>
                    <measurement group_id="O4" value="-0.3" spread="12.37"/>
                    <measurement group_id="O5" value="13.9" spread="24.15"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-20.0" spread="2.83"/>
                    <measurement group_id="O6" value="-11.7" spread="30.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Day 2,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.078" spread="0.8813"/>
                    <measurement group_id="O2" value="0.413" spread="0.6493"/>
                    <measurement group_id="O3" value="-0.005" spread="0.9228"/>
                    <measurement group_id="O4" value="0.301" spread="0.5042"/>
                    <measurement group_id="O5" value="0.241" spread="0.8219"/>
                    <measurement group_id="O6" value="0.102" spread="0.4630"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.161" spread="0.4542"/>
                    <measurement group_id="O2" value="0.015" spread="0.6691"/>
                    <measurement group_id="O3" value="0.225" spread="0.6850"/>
                    <measurement group_id="O4" value="0.077" spread="0.9525"/>
                    <measurement group_id="O5" value="0.217" spread="1.1014"/>
                    <measurement group_id="O6" value="0.038" spread="0.5158"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.390" spread="0.4832"/>
                    <measurement group_id="O2" value="0.560" spread="0.4666"/>
                    <measurement group_id="O3" value="0.438" spread="0.9293"/>
                    <measurement group_id="O4" value="0.151" spread="0.9472"/>
                    <measurement group_id="O5" value="0.130" spread="1.0414"/>
                    <measurement group_id="O6" value="0.215" spread="0.4194"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Day 5,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.155" spread="0.7789"/>
                    <measurement group_id="O2" value="0.085" spread="0.6109"/>
                    <measurement group_id="O3" value="-0.003" spread="0.3494"/>
                    <measurement group_id="O4" value="0.041" spread="0.7075"/>
                    <measurement group_id="O5" value="0.184" spread="1.0809"/>
                    <measurement group_id="O6" value="0.103" spread="0.2639"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.179" spread="0.6365"/>
                    <measurement group_id="O2" value="-0.483" spread="1.2069"/>
                    <measurement group_id="O3" value="-0.160" spread="0.3280"/>
                    <measurement group_id="O4" value="-0.151" spread="0.5955"/>
                    <measurement group_id="O5" value="0.174" spread="0.8992"/>
                    <measurement group_id="O6" value="0.070" spread="0.4346"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.209" spread="0.4662"/>
                    <measurement group_id="O2" value="-0.738" spread="0.7110"/>
                    <measurement group_id="O3" value="-0.142" spread="1.0604"/>
                    <measurement group_id="O4" value="-0.192" spread="0.9481"/>
                    <measurement group_id="O5" value="0.229" spread="0.8853"/>
                    <measurement group_id="O6" value="-0.310" spread="0.6362"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.540" spread="0.4797"/>
                    <measurement group_id="O2" value="-0.768" spread="0.7810"/>
                    <measurement group_id="O3" value="-0.156" spread="0.9674"/>
                    <measurement group_id="O4" value="-0.279" spread="0.5859"/>
                    <measurement group_id="O5" value="-0.340" spread="0.7049"/>
                    <measurement group_id="O6" value="0.023" spread="0.7539"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.218" spread="0.7893"/>
                    <measurement group_id="O2" value="0.497" spread="1.6165"/>
                    <measurement group_id="O3" value="-0.277" spread="0.9128"/>
                    <measurement group_id="O4" value="-0.069" spread="1.0047"/>
                    <measurement group_id="O5" value="-0.127" spread="0.5829"/>
                    <measurement group_id="O6" value="0.258" spread="0.5218"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 12,n=12,5,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.043" spread="0.9639"/>
                    <measurement group_id="O2" value="-0.712" spread="0.5890"/>
                    <measurement group_id="O3" value="0.053" spread="1.0187"/>
                    <measurement group_id="O4" value="-0.180" spread="0.4760"/>
                    <measurement group_id="O5" value="-0.344" spread="0.4840"/>
                    <measurement group_id="O6" value="-0.362" spread="0.5607"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.093" spread="0.9727"/>
                    <measurement group_id="O2" value="-0.158" spread="0.7786"/>
                    <measurement group_id="O3" value="0.015" spread="0.7474"/>
                    <measurement group_id="O4" value="-0.012" spread="0.8076"/>
                    <measurement group_id="O5" value="-0.151" spread="0.5728"/>
                    <measurement group_id="O6" value="-0.027" spread="0.6629"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.326" spread="0.4501"/>
                    <measurement group_id="O2" value="-0.752" spread="0.9422"/>
                    <measurement group_id="O3" value="-0.370" spread="0.3746"/>
                    <measurement group_id="O4" value="-0.144" spread="0.5243"/>
                    <measurement group_id="O5" value="0.140" spread="0.5795"/>
                    <measurement group_id="O6" value="-0.128" spread="0.4311"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.105" spread="0.7933"/>
                    <measurement group_id="O2" value="-0.527" spread="0.6332"/>
                    <measurement group_id="O3" value="-0.622" spread="0.6065"/>
                    <measurement group_id="O4" value="-0.259" spread="0.9389"/>
                    <measurement group_id="O5" value="0.104" spread="0.7127"/>
                    <measurement group_id="O6" value="-0.295" spread="0.2855"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.393" spread="0.8219"/>
                    <measurement group_id="O2" value="-0.708" spread="0.7757"/>
                    <measurement group_id="O3" value="0.880" spread="1.9211"/>
                    <measurement group_id="O6" value="-0.360" spread="0.3275"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.163" spread="0.8441"/>
                    <measurement group_id="O4" value="-0.384" spread="0.4763"/>
                    <measurement group_id="O5" value="-0.004" spread="0.9080"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.005" spread="0.1061"/>
                    <measurement group_id="O6" value="0.332" spread="0.3452"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Red Blood Cell Count (RBC)</title>
        <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like RBC count. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Red Blood Cell Count (RBC)</title>
          <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like RBC count. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Trillion cells per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.08" spread="0.212"/>
                    <measurement group_id="O2" value="-0.07" spread="0.197"/>
                    <measurement group_id="O3" value="0.08" spread="0.223"/>
                    <measurement group_id="O4" value="0.00" spread="0.194"/>
                    <measurement group_id="O5" value="0.16" spread="0.246"/>
                    <measurement group_id="O6" value="0.05" spread="0.243"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.03" spread="0.214"/>
                    <measurement group_id="O2" value="-0.08" spread="0.133"/>
                    <measurement group_id="O3" value="0.13" spread="0.242"/>
                    <measurement group_id="O4" value="0.01" spread="0.190"/>
                    <measurement group_id="O5" value="0.06" spread="0.133"/>
                    <measurement group_id="O6" value="0.03" spread="0.186"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.04" spread="0.211"/>
                    <measurement group_id="O2" value="-0.08" spread="0.133"/>
                    <measurement group_id="O3" value="0.10" spread="0.179"/>
                    <measurement group_id="O4" value="-0.03" spread="0.149"/>
                    <measurement group_id="O5" value="0.04" spread="0.185"/>
                    <measurement group_id="O6" value="0.10" spread="0.141"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.18" spread="0.175"/>
                    <measurement group_id="O2" value="-0.22" spread="0.133"/>
                    <measurement group_id="O3" value="-0.10" spread="0.261"/>
                    <measurement group_id="O4" value="-0.08" spread="0.120"/>
                    <measurement group_id="O5" value="0.03" spread="0.316"/>
                    <measurement group_id="O6" value="0.05" spread="0.187"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.15" spread="0.215"/>
                    <measurement group_id="O2" value="-0.37" spread="0.175"/>
                    <measurement group_id="O3" value="0.00" spread="0.190"/>
                    <measurement group_id="O4" value="-0.03" spread="0.218"/>
                    <measurement group_id="O5" value="0.07" spread="0.180"/>
                    <measurement group_id="O6" value="-0.02" spread="0.147"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.11" spread="0.156"/>
                    <measurement group_id="O2" value="-0.28" spread="0.133"/>
                    <measurement group_id="O3" value="-0.18" spread="0.183"/>
                    <measurement group_id="O4" value="-0.07" spread="0.206"/>
                    <measurement group_id="O5" value="0.11" spread="0.232"/>
                    <measurement group_id="O6" value="-0.08" spread="0.194"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.18" spread="0.248"/>
                    <measurement group_id="O2" value="-0.35" spread="0.055"/>
                    <measurement group_id="O3" value="-0.16" spread="0.230"/>
                    <measurement group_id="O4" value="-0.08" spread="0.192"/>
                    <measurement group_id="O5" value="0.09" spread="0.293"/>
                    <measurement group_id="O6" value="-0.03" spread="0.137"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.03" spread="0.253"/>
                    <measurement group_id="O2" value="-0.23" spread="0.186"/>
                    <measurement group_id="O3" value="-0.02" spread="0.248"/>
                    <measurement group_id="O4" value="-0.13" spread="0.200"/>
                    <measurement group_id="O5" value="0.18" spread="0.277"/>
                    <measurement group_id="O6" value="0.07" spread="0.103"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.13" spread="0.176"/>
                    <measurement group_id="O2" value="-0.25" spread="0.138"/>
                    <measurement group_id="O3" value="-0.05" spread="0.251"/>
                    <measurement group_id="O4" value="-0.01" spread="0.237"/>
                    <measurement group_id="O5" value="0.19" spread="0.237"/>
                    <measurement group_id="O6" value="0.00" spread="0.141"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.02" spread="0.292"/>
                    <measurement group_id="O2" value="-0.20" spread="0.219"/>
                    <measurement group_id="O3" value="-0.08" spread="0.271"/>
                    <measurement group_id="O4" value="-0.02" spread="0.228"/>
                    <measurement group_id="O5" value="0.27" spread="0.283"/>
                    <measurement group_id="O6" value="0.17" spread="0.163"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.11" spread="0.221"/>
                    <measurement group_id="O2" value="-0.27" spread="0.175"/>
                    <measurement group_id="O3" value="-0.05" spread="0.164"/>
                    <measurement group_id="O4" value="0.01" spread="0.169"/>
                    <measurement group_id="O5" value="0.13" spread="0.229"/>
                    <measurement group_id="O6" value="0.17" spread="0.151"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.12" spread="0.301"/>
                    <measurement group_id="O2" value="-0.33" spread="0.216"/>
                    <measurement group_id="O3" value="-0.08" spread="0.204"/>
                    <measurement group_id="O4" value="-0.02" spread="0.120"/>
                    <measurement group_id="O5" value="0.20" spread="0.194"/>
                    <measurement group_id="O6" value="0.12" spread="0.117"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.10" spread="0.237"/>
                    <measurement group_id="O2" value="-0.18" spread="0.183"/>
                    <measurement group_id="O3" value="0.08" spread="0.248"/>
                    <measurement group_id="O6" value="0.05" spread="0.176"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.12" spread="0.232"/>
                    <measurement group_id="O4" value="0.10" spread="0.122"/>
                    <measurement group_id="O5" value="0.33" spread="0.357"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.05" spread="0.071"/>
                    <measurement group_id="O6" value="0.12" spread="0.098"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Mean Corpuscle Volume (MCV)</title>
        <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like MCV. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Mean Corpuscle Volume (MCV)</title>
          <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like MCV. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Femtoliters</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2" spread="0.94"/>
                    <measurement group_id="O2" value="0.2" spread="0.75"/>
                    <measurement group_id="O3" value="0.2" spread="0.75"/>
                    <measurement group_id="O4" value="0.1" spread="2.85"/>
                    <measurement group_id="O5" value="-0.3" spread="1.00"/>
                    <measurement group_id="O6" value="1.3" spread="2.16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="1.07"/>
                    <measurement group_id="O2" value="-0.3" spread="0.82"/>
                    <measurement group_id="O3" value="0.2" spread="0.75"/>
                    <measurement group_id="O4" value="0.0" spread="1.32"/>
                    <measurement group_id="O5" value="-1.0" spread="1.41"/>
                    <measurement group_id="O6" value="0.3" spread="1.37"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="0.78"/>
                    <measurement group_id="O2" value="-0.5" spread="1.05"/>
                    <measurement group_id="O3" value="0.0" spread="1.26"/>
                    <measurement group_id="O4" value="-0.1" spread="0.83"/>
                    <measurement group_id="O5" value="-1.8" spread="0.89"/>
                    <measurement group_id="O6" value="0.2" spread="0.98"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.3" spread="1.92"/>
                    <measurement group_id="O2" value="0.5" spread="0.55"/>
                    <measurement group_id="O3" value="0.3" spread="0.82"/>
                    <measurement group_id="O4" value="2.0" spread="2.92"/>
                    <measurement group_id="O5" value="-1.0" spread="3.50"/>
                    <measurement group_id="O6" value="0.7" spread="1.75"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="0.94"/>
                    <measurement group_id="O2" value="-0.8" spread="1.33"/>
                    <measurement group_id="O3" value="0.2" spread="0.75"/>
                    <measurement group_id="O4" value="-1.2" spread="1.20"/>
                    <measurement group_id="O5" value="-1.7" spread="2.06"/>
                    <measurement group_id="O6" value="-0.7" spread="1.21"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="1.28"/>
                    <measurement group_id="O2" value="-0.3" spread="1.51"/>
                    <measurement group_id="O3" value="0.2" spread="0.75"/>
                    <measurement group_id="O4" value="-0.9" spread="1.17"/>
                    <measurement group_id="O5" value="-1.4" spread="2.51"/>
                    <measurement group_id="O6" value="-0.3" spread="1.63"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="2.39"/>
                    <measurement group_id="O2" value="-0.8" spread="2.14"/>
                    <measurement group_id="O3" value="0.2" spread="0.45"/>
                    <measurement group_id="O4" value="-0.7" spread="0.87"/>
                    <measurement group_id="O5" value="-1.6" spread="2.13"/>
                    <measurement group_id="O6" value="-0.2" spread="0.98"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="1.23"/>
                    <measurement group_id="O2" value="-0.3" spread="1.51"/>
                    <measurement group_id="O3" value="0.2" spread="0.75"/>
                    <measurement group_id="O4" value="0.0" spread="1.12"/>
                    <measurement group_id="O5" value="-2.2" spread="2.91"/>
                    <measurement group_id="O6" value="-0.2" spread="1.17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="1.09"/>
                    <measurement group_id="O2" value="-1.2" spread="1.94"/>
                    <measurement group_id="O3" value="0.2" spread="0.75"/>
                    <measurement group_id="O4" value="-0.7" spread="1.87"/>
                    <measurement group_id="O5" value="-2.4" spread="2.55"/>
                    <measurement group_id="O6" value="-1.2" spread="0.84"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.4" spread="1.73"/>
                    <measurement group_id="O2" value="-0.8" spread="1.33"/>
                    <measurement group_id="O3" value="0.5" spread="1.64"/>
                    <measurement group_id="O4" value="-1.9" spread="1.05"/>
                    <measurement group_id="O5" value="-2.8" spread="3.07"/>
                    <measurement group_id="O6" value="-1.0" spread="1.10"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="1.78"/>
                    <measurement group_id="O2" value="-0.3" spread="1.86"/>
                    <measurement group_id="O3" value="0.8" spread="1.72"/>
                    <measurement group_id="O4" value="-1.6" spread="1.51"/>
                    <measurement group_id="O5" value="-2.4" spread="3.54"/>
                    <measurement group_id="O6" value="-0.7" spread="1.03"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="2.24"/>
                    <measurement group_id="O2" value="0.0" spread="2.10"/>
                    <measurement group_id="O3" value="0.5" spread="0.84"/>
                    <measurement group_id="O4" value="-1.7" spread="1.58"/>
                    <measurement group_id="O5" value="-2.3" spread="3.04"/>
                    <measurement group_id="O6" value="-0.3" spread="1.03"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="1.38"/>
                    <measurement group_id="O2" value="0.0" spread="2.45"/>
                    <measurement group_id="O3" value="0.8" spread="1.47"/>
                    <measurement group_id="O6" value="-0.2" spread="0.98"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="1.05"/>
                    <measurement group_id="O4" value="-1.9" spread="1.05"/>
                    <measurement group_id="O5" value="-1.8" spread="2.44"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="0.71"/>
                    <measurement group_id="O6" value="1.2" spread="0.75"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Mean Corpuscle Hemoglobin (MCH)</title>
        <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like MCH. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Mean Corpuscle Hemoglobin (MCH)</title>
          <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like MCH. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Picograms</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.03" spread="0.588"/>
                    <measurement group_id="O2" value="0.23" spread="0.388"/>
                    <measurement group_id="O3" value="0.02" spread="0.299"/>
                    <measurement group_id="O4" value="-0.04" spread="0.255"/>
                    <measurement group_id="O5" value="-0.02" spread="0.277"/>
                    <measurement group_id="O6" value="-0.07" spread="0.450"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.13" spread="0.485"/>
                    <measurement group_id="O2" value="0.25" spread="0.389"/>
                    <measurement group_id="O3" value="0.10" spread="0.283"/>
                    <measurement group_id="O4" value="-0.02" spread="0.228"/>
                    <measurement group_id="O5" value="0.20" spread="0.444"/>
                    <measurement group_id="O6" value="-0.08" spread="0.172"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.14" spread="0.542"/>
                    <measurement group_id="O2" value="0.17" spread="0.480"/>
                    <measurement group_id="O3" value="0.18" spread="0.299"/>
                    <measurement group_id="O4" value="0.05" spread="0.351"/>
                    <measurement group_id="O5" value="0.01" spread="0.432"/>
                    <measurement group_id="O6" value="0.12" spread="0.325"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.08" spread="0.626"/>
                    <measurement group_id="O2" value="0.17" spread="0.314"/>
                    <measurement group_id="O3" value="0.22" spread="0.449"/>
                    <measurement group_id="O4" value="-0.03" spread="0.346"/>
                    <measurement group_id="O5" value="0.02" spread="0.331"/>
                    <measurement group_id="O6" value="-0.22" spread="0.240"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.07" spread="0.433"/>
                    <measurement group_id="O2" value="0.38" spread="0.542"/>
                    <measurement group_id="O3" value="-0.07" spread="0.273"/>
                    <measurement group_id="O4" value="0.00" spread="0.381"/>
                    <measurement group_id="O5" value="0.00" spread="0.427"/>
                    <measurement group_id="O6" value="-0.08" spread="0.553"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.02" spread="0.495"/>
                    <measurement group_id="O2" value="0.33" spread="0.516"/>
                    <measurement group_id="O3" value="0.25" spread="0.418"/>
                    <measurement group_id="O4" value="-0.08" spread="0.331"/>
                    <measurement group_id="O5" value="-0.04" spread="0.088"/>
                    <measurement group_id="O6" value="-0.02" spread="0.240"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.15" spread="1.153"/>
                    <measurement group_id="O2" value="0.30" spread="0.374"/>
                    <measurement group_id="O3" value="0.12" spread="0.268"/>
                    <measurement group_id="O4" value="-0.29" spread="0.404"/>
                    <measurement group_id="O5" value="-0.06" spread="0.394"/>
                    <measurement group_id="O6" value="-0.22" spread="0.343"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.06" spread="0.429"/>
                    <measurement group_id="O2" value="0.25" spread="0.860"/>
                    <measurement group_id="O3" value="0.30" spread="0.410"/>
                    <measurement group_id="O4" value="-0.30" spread="0.287"/>
                    <measurement group_id="O5" value="-0.11" spread="0.655"/>
                    <measurement group_id="O6" value="-0.22" spread="0.286"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.08" spread="0.583"/>
                    <measurement group_id="O2" value="0.32" spread="0.882"/>
                    <measurement group_id="O3" value="0.02" spread="0.624"/>
                    <measurement group_id="O4" value="-0.42" spread="0.415"/>
                    <measurement group_id="O5" value="-0.04" spread="0.541"/>
                    <measurement group_id="O6" value="-0.60" spread="0.561"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.13" spread="0.805"/>
                    <measurement group_id="O2" value="0.78" spread="0.382"/>
                    <measurement group_id="O3" value="-0.10" spread="0.616"/>
                    <measurement group_id="O4" value="-0.37" spread="0.384"/>
                    <measurement group_id="O5" value="0.01" spread="0.627"/>
                    <measurement group_id="O6" value="-0.78" spread="0.382"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.44" spread="0.883"/>
                    <measurement group_id="O2" value="0.87" spread="0.799"/>
                    <measurement group_id="O3" value="0.23" spread="0.356"/>
                    <measurement group_id="O4" value="-0.37" spread="0.510"/>
                    <measurement group_id="O5" value="-0.37" spread="0.632"/>
                    <measurement group_id="O6" value="-0.90" spread="0.237"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.27" spread="0.946"/>
                    <measurement group_id="O2" value="1.05" spread="0.505"/>
                    <measurement group_id="O3" value="0.10" spread="0.473"/>
                    <measurement group_id="O4" value="-0.38" spread="0.432"/>
                    <measurement group_id="O5" value="-0.71" spread="0.818"/>
                    <measurement group_id="O6" value="-1.07" spread="0.393"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.22" spread="0.975"/>
                    <measurement group_id="O2" value="0.67" spread="0.625"/>
                    <measurement group_id="O3" value="0.53" spread="0.909"/>
                    <measurement group_id="O6" value="-0.58" spread="0.331"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.00" spread="0.525"/>
                    <measurement group_id="O4" value="-1.00" spread="0.403"/>
                    <measurement group_id="O5" value="-0.68" spread="0.438"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.55" spread="0.071"/>
                    <measurement group_id="O6" value="-0.68" spread="0.232"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Hemoglobin</title>
        <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like hemoglobin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Hemoglobin</title>
          <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like hemoglobin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Grams per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.4" spread="6.83"/>
                    <measurement group_id="O2" value="0.3" spread="6.80"/>
                    <measurement group_id="O3" value="3.7" spread="7.09"/>
                    <measurement group_id="O4" value="-0.4" spread="6.00"/>
                    <measurement group_id="O5" value="4.3" spread="7.12"/>
                    <measurement group_id="O6" value="0.2" spread="8.52"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.6" spread="6.78"/>
                    <measurement group_id="O2" value="-0.5" spread="4.04"/>
                    <measurement group_id="O3" value="5.8" spread="8.80"/>
                    <measurement group_id="O4" value="0.1" spread="6.62"/>
                    <measurement group_id="O5" value="2.2" spread="4.35"/>
                    <measurement group_id="O6" value="-0.5" spread="5.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="6.69"/>
                    <measurement group_id="O2" value="-1.3" spread="4.59"/>
                    <measurement group_id="O3" value="3.7" spread="6.02"/>
                    <measurement group_id="O4" value="-1.0" spread="4.14"/>
                    <measurement group_id="O5" value="1.4" spread="5.32"/>
                    <measurement group_id="O6" value="3.2" spread="5.12"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.0" spread="4.65"/>
                    <measurement group_id="O2" value="-4.8" spread="3.82"/>
                    <measurement group_id="O3" value="-0.3" spread="7.84"/>
                    <measurement group_id="O4" value="-2.9" spread="4.54"/>
                    <measurement group_id="O5" value="0.8" spread="8.86"/>
                    <measurement group_id="O6" value="-0.3" spread="5.13"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.9" spread="6.50"/>
                    <measurement group_id="O2" value="-8.3" spread="5.28"/>
                    <measurement group_id="O3" value="0.2" spread="6.79"/>
                    <measurement group_id="O4" value="-1.4" spread="7.00"/>
                    <measurement group_id="O5" value="2.0" spread="6.42"/>
                    <measurement group_id="O6" value="-1.5" spread="3.27"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.3" spread="5.79"/>
                    <measurement group_id="O2" value="-6.2" spread="4.67"/>
                    <measurement group_id="O3" value="-3.7" spread="5.72"/>
                    <measurement group_id="O4" value="-2.4" spread="6.29"/>
                    <measurement group_id="O5" value="3.3" spread="7.73"/>
                    <measurement group_id="O6" value="-3.5" spread="6.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.2" spread="5.08"/>
                    <measurement group_id="O2" value="-8.0" spread="4.10"/>
                    <measurement group_id="O3" value="-3.0" spread="7.94"/>
                    <measurement group_id="O4" value="-4.2" spread="6.61"/>
                    <measurement group_id="O5" value="2.6" spread="10.36"/>
                    <measurement group_id="O6" value="-2.5" spread="4.09"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.1" spread="8.83"/>
                    <measurement group_id="O2" value="-4.8" spread="4.96"/>
                    <measurement group_id="O3" value="1.5" spread="8.71"/>
                    <measurement group_id="O4" value="-5.6" spread="6.27"/>
                    <measurement group_id="O5" value="4.9" spread="7.80"/>
                    <measurement group_id="O6" value="-0.2" spread="2.48"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.3" spread="6.50"/>
                    <measurement group_id="O2" value="-4.8" spread="4.49"/>
                    <measurement group_id="O3" value="-0.2" spread="9.28"/>
                    <measurement group_id="O4" value="-2.8" spread="7.98"/>
                    <measurement group_id="O5" value="5.9" spread="6.39"/>
                    <measurement group_id="O6" value="-3.6" spread="2.07"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.6" spread="8.47"/>
                    <measurement group_id="O2" value="-1.8" spread="6.77"/>
                    <measurement group_id="O3" value="-2.3" spread="6.62"/>
                    <measurement group_id="O4" value="-2.4" spread="6.09"/>
                    <measurement group_id="O5" value="8.3" spread="9.25"/>
                    <measurement group_id="O6" value="0.5" spread="4.72"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.3" spread="8.31"/>
                    <measurement group_id="O2" value="-3.2" spread="7.99"/>
                    <measurement group_id="O3" value="0.5" spread="6.09"/>
                    <measurement group_id="O4" value="-1.7" spread="6.36"/>
                    <measurement group_id="O5" value="2.4" spread="7.67"/>
                    <measurement group_id="O6" value="-0.2" spread="3.37"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.6" spread="9.70"/>
                    <measurement group_id="O2" value="-4.5" spread="8.07"/>
                    <measurement group_id="O3" value="-1.0" spread="5.76"/>
                    <measurement group_id="O4" value="-2.2" spread="3.42"/>
                    <measurement group_id="O5" value="2.9" spread="6.23"/>
                    <measurement group_id="O6" value="-2.7" spread="4.32"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="3.78"/>
                    <measurement group_id="O2" value="-1.8" spread="4.79"/>
                    <measurement group_id="O3" value="5.2" spread="8.38"/>
                    <measurement group_id="O6" value="-1.8" spread="5.71"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="8.47"/>
                    <measurement group_id="O4" value="-2.4" spread="3.13"/>
                    <measurement group_id="O5" value="6.9" spread="10.67"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.5" spread="3.54"/>
                    <measurement group_id="O6" value="-0.2" spread="4.17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Hematocrit</title>
        <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like hematocrit. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Hematocrit</title>
          <description>Blood samples were collected at indicated time-points for analysis of hematology parameters like hematocrit. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Proportion of red blood cells in blood</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="0.01961"/>
                    <measurement group_id="O2" value="-0.001" spread="0.01884"/>
                    <measurement group_id="O3" value="0.009" spread="0.02262"/>
                    <measurement group_id="O4" value="0.000" spread="0.01500"/>
                    <measurement group_id="O5" value="0.011" spread="0.02356"/>
                    <measurement group_id="O6" value="0.007" spread="0.02689"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.005" spread="0.01925"/>
                    <measurement group_id="O2" value="-0.007" spread="0.01374"/>
                    <measurement group_id="O3" value="0.014" spread="0.02667"/>
                    <measurement group_id="O4" value="0.001" spread="0.01634"/>
                    <measurement group_id="O5" value="-0.000" spread="0.01198"/>
                    <measurement group_id="O6" value="0.001" spread="0.01584"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,8,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.003" spread="0.01777"/>
                    <measurement group_id="O2" value="-0.009" spread="0.01803"/>
                    <measurement group_id="O3" value="0.005" spread="0.02170"/>
                    <measurement group_id="O4" value="-0.003" spread="0.01663"/>
                    <measurement group_id="O5" value="-0.004" spread="0.01858"/>
                    <measurement group_id="O6" value="0.008" spread="0.01251"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.01509"/>
                    <measurement group_id="O2" value="-0.015" spread="0.01340"/>
                    <measurement group_id="O3" value="-0.004" spread="0.02743"/>
                    <measurement group_id="O4" value="0.001" spread="0.01970"/>
                    <measurement group_id="O5" value="-0.001" spread="0.03295"/>
                    <measurement group_id="O6" value="0.006" spread="0.01061"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.014" spread="0.01894"/>
                    <measurement group_id="O2" value="-0.034" spread="0.01549"/>
                    <measurement group_id="O3" value="0.000" spread="0.02138"/>
                    <measurement group_id="O4" value="-0.008" spread="0.02644"/>
                    <measurement group_id="O5" value="-0.001" spread="0.02068"/>
                    <measurement group_id="O6" value="-0.005" spread="0.01076"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.01670"/>
                    <measurement group_id="O2" value="-0.025" spread="0.01626"/>
                    <measurement group_id="O3" value="-0.016" spread="0.01928"/>
                    <measurement group_id="O4" value="-0.009" spread="0.01960"/>
                    <measurement group_id="O5" value="0.002" spread="0.02469"/>
                    <measurement group_id="O6" value="-0.011" spread="0.01759"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.011" spread="0.01840"/>
                    <measurement group_id="O2" value="-0.032" spread="0.01393"/>
                    <measurement group_id="O3" value="-0.010" spread="0.02192"/>
                    <measurement group_id="O4" value="-0.010" spread="0.02063"/>
                    <measurement group_id="O5" value="0.001" spread="0.02962"/>
                    <measurement group_id="O6" value="-0.004" spread="0.01315"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.001" spread="0.02285"/>
                    <measurement group_id="O2" value="-0.020" spread="0.02119"/>
                    <measurement group_id="O3" value="-0.000" spread="0.02367"/>
                    <measurement group_id="O4" value="-0.011" spread="0.01889"/>
                    <measurement group_id="O5" value="0.005" spread="0.03084"/>
                    <measurement group_id="O6" value="0.002" spread="0.00750"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.01745"/>
                    <measurement group_id="O2" value="-0.025" spread="0.01262"/>
                    <measurement group_id="O3" value="-0.001" spread="0.02587"/>
                    <measurement group_id="O4" value="-0.005" spread="0.02379"/>
                    <measurement group_id="O5" value="0.006" spread="0.02343"/>
                    <measurement group_id="O6" value="-0.006" spread="0.01279"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.02680"/>
                    <measurement group_id="O2" value="-0.020" spread="0.02140"/>
                    <measurement group_id="O3" value="-0.005" spread="0.03041"/>
                    <measurement group_id="O4" value="-0.010" spread="0.02016"/>
                    <measurement group_id="O5" value="0.012" spread="0.02972"/>
                    <measurement group_id="O6" value="0.008" spread="0.01515"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="0.02108"/>
                    <measurement group_id="O2" value="-0.023" spread="0.02325"/>
                    <measurement group_id="O3" value="0.001" spread="0.01955"/>
                    <measurement group_id="O4" value="-0.006" spread="0.01726"/>
                    <measurement group_id="O5" value="0.001" spread="0.02607"/>
                    <measurement group_id="O6" value="0.009" spread="0.01184"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="0.02378"/>
                    <measurement group_id="O2" value="-0.029" spread="0.02593"/>
                    <measurement group_id="O3" value="-0.004" spread="0.01813"/>
                    <measurement group_id="O4" value="-0.007" spread="0.01424"/>
                    <measurement group_id="O5" value="0.008" spread="0.01829"/>
                    <measurement group_id="O6" value="0.006" spread="0.01091"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.005" spread="0.01904"/>
                    <measurement group_id="O2" value="-0.015" spread="0.02220"/>
                    <measurement group_id="O3" value="0.009" spread="0.02413"/>
                    <measurement group_id="O6" value="0.002" spread="0.01851"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.001" spread="0.01862"/>
                    <measurement group_id="O4" value="-0.001" spread="0.01237"/>
                    <measurement group_id="O5" value="0.022" spread="0.03464"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.00495"/>
                    <measurement group_id="O6" value="0.016" spread="0.00816"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Clinical Chemistry Parameter: High Sensitivity C-reactive Protein (hsCRP)</title>
        <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like hsCRP. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Clinical Chemistry Parameter: High Sensitivity C-reactive Protein (hsCRP)</title>
          <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like hsCRP. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Milligrams per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3443" spread="0.44689"/>
                    <measurement group_id="O2" value="-0.1217" spread="0.28604"/>
                    <measurement group_id="O3" value="-0.7367" spread="0.90943"/>
                    <measurement group_id="O4" value="-0.3178" spread="0.45880"/>
                    <measurement group_id="O5" value="-1.0956" spread="1.50219"/>
                    <measurement group_id="O6" value="-0.4867" spread="0.50816"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.4376" spread="0.43692"/>
                    <measurement group_id="O2" value="-0.1417" spread="0.25818"/>
                    <measurement group_id="O3" value="-0.8200" spread="1.10247"/>
                    <measurement group_id="O4" value="-0.4367" spread="0.71042"/>
                    <measurement group_id="O5" value="-1.4100" spread="2.19445"/>
                    <measurement group_id="O6" value="-0.4817" spread="0.53663"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.4570" spread="0.42874"/>
                    <measurement group_id="O2" value="-0.1917" spread="0.23095"/>
                    <measurement group_id="O3" value="-0.8683" spread="1.21224"/>
                    <measurement group_id="O4" value="-0.5356" spread="0.91155"/>
                    <measurement group_id="O5" value="-1.5311" spread="2.32545"/>
                    <measurement group_id="O6" value="-0.5867" spread="0.66476"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3953" spread="0.37761"/>
                    <measurement group_id="O2" value="-0.0117" spread="0.31244"/>
                    <measurement group_id="O3" value="-0.7150" spread="1.23395"/>
                    <measurement group_id="O4" value="-0.5322" spread="0.95860"/>
                    <measurement group_id="O5" value="-1.4289" spread="2.35532"/>
                    <measurement group_id="O6" value="-0.5867" spread="0.77590"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=11,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2176" spread="0.37960"/>
                    <measurement group_id="O2" value="0.2183" spread="0.23086"/>
                    <measurement group_id="O3" value="-0.3033" spread="1.32284"/>
                    <measurement group_id="O4" value="-0.5772" spread="0.86704"/>
                    <measurement group_id="O5" value="-1.3156" spread="2.57735"/>
                    <measurement group_id="O6" value="-0.5717" spread="0.69534"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0638" spread="0.44620"/>
                    <measurement group_id="O2" value="0.0167" spread="0.21435"/>
                    <measurement group_id="O3" value="-0.6967" spread="1.30606"/>
                    <measurement group_id="O4" value="0.1733" spread="0.86781"/>
                    <measurement group_id="O5" value="0.2478" spread="2.91047"/>
                    <measurement group_id="O6" value="-0.0967" spread="0.50091"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1253" spread="0.55902"/>
                    <measurement group_id="O2" value="0.1433" spread="0.66069"/>
                    <measurement group_id="O3" value="-0.6433" spread="1.28969"/>
                    <measurement group_id="O4" value="-0.2689" spread="0.86847"/>
                    <measurement group_id="O5" value="2.6422" spread="11.57024"/>
                    <measurement group_id="O6" value="-0.4317" spread="0.54653"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5955" spread="1.62268"/>
                    <measurement group_id="O2" value="1.2817" spread="1.79930"/>
                    <measurement group_id="O3" value="-0.3633" spread="1.66310"/>
                    <measurement group_id="O4" value="-0.0878" spread="0.61243"/>
                    <measurement group_id="O5" value="-1.1656" spread="2.91829"/>
                    <measurement group_id="O6" value="-0.2517" spread="0.74440"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1455" spread="1.29507"/>
                    <measurement group_id="O2" value="-0.1033" spread="0.36784"/>
                    <measurement group_id="O3" value="0.1250" spread="0.61656"/>
                    <measurement group_id="O4" value="0.9089" spread="1.31831"/>
                    <measurement group_id="O5" value="-0.4067" spread="3.85725"/>
                    <measurement group_id="O6" value="0.1000" spread="0.55274"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1538" spread="0.54412"/>
                    <measurement group_id="O2" value="0.1883" spread="0.22851"/>
                    <measurement group_id="O3" value="0.1317" spread="1.77035"/>
                    <measurement group_id="O4" value="0.0700" spread="1.19067"/>
                    <measurement group_id="O5" value="-1.1267" spread="2.89881"/>
                    <measurement group_id="O6" value="-0.3300" spread="0.53457"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1163" spread="1.06052"/>
                    <measurement group_id="O2" value="0.4383" spread="1.46248"/>
                    <measurement group_id="O3" value="-0.6383" spread="1.36902"/>
                    <measurement group_id="O4" value="0.1356" spread="0.80296"/>
                    <measurement group_id="O5" value="-0.7989" spread="3.36420"/>
                    <measurement group_id="O6" value="-0.2142" spread="1.09332"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2438" spread="0.75525"/>
                    <measurement group_id="O2" value="1.6333" spread="3.95614"/>
                    <measurement group_id="O3" value="-0.6383" spread="1.13732"/>
                    <measurement group_id="O4" value="0.3344" spread="0.53761"/>
                    <measurement group_id="O5" value="-0.6933" spread="3.25344"/>
                    <measurement group_id="O6" value="0.2400" spread="0.76467"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,5,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.6393" spread="1.03514"/>
                    <measurement group_id="O2" value="0.2860" spread="0.82509"/>
                    <measurement group_id="O3" value="-0.2400" spread="1.63862"/>
                    <measurement group_id="O6" value="-0.1367" spread="0.73277"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.4917" spread="1.31750"/>
                    <measurement group_id="O4" value="-0.5456" spread="1.15831"/>
                    <measurement group_id="O5" value="-0.1911" spread="3.93159"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1450" spread="0.00707"/>
                    <measurement group_id="O6" value="0.4333" spread="1.74105"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Clinical Chemistry Parameter of Total Protein and Albumin</title>
        <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like total protein and albumin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Clinical Chemistry Parameter of Total Protein and Albumin</title>
          <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like total protein and albumin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Grams per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Total protein, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="3.74"/>
                    <measurement group_id="O2" value="-2.3" spread="1.97"/>
                    <measurement group_id="O3" value="-0.6" spread="3.36"/>
                    <measurement group_id="O4" value="-3.8" spread="3.56"/>
                    <measurement group_id="O5" value="0.7" spread="4.90"/>
                    <measurement group_id="O6" value="-0.2" spread="4.40"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.4" spread="3.68"/>
                    <measurement group_id="O2" value="-2.5" spread="2.17"/>
                    <measurement group_id="O3" value="0.2" spread="3.43"/>
                    <measurement group_id="O4" value="-1.7" spread="4.18"/>
                    <measurement group_id="O5" value="-0.7" spread="3.16"/>
                    <measurement group_id="O6" value="0.0" spread="3.22"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="4.34"/>
                    <measurement group_id="O2" value="-1.2" spread="2.14"/>
                    <measurement group_id="O3" value="0.3" spread="2.58"/>
                    <measurement group_id="O4" value="-2.8" spread="3.46"/>
                    <measurement group_id="O5" value="-0.4" spread="2.65"/>
                    <measurement group_id="O6" value="1.7" spread="2.88"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.3" spread="2.77"/>
                    <measurement group_id="O2" value="-2.7" spread="2.58"/>
                    <measurement group_id="O3" value="-0.7" spread="4.72"/>
                    <measurement group_id="O4" value="-3.2" spread="4.02"/>
                    <measurement group_id="O5" value="0.1" spread="5.78"/>
                    <measurement group_id="O6" value="0.0" spread="3.41"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.6" spread="2.87"/>
                    <measurement group_id="O2" value="-2.3" spread="4.23"/>
                    <measurement group_id="O3" value="-2.8" spread="2.99"/>
                    <measurement group_id="O4" value="-1.2" spread="4.29"/>
                    <measurement group_id="O5" value="-1.1" spread="3.62"/>
                    <measurement group_id="O6" value="-1.4" spread="1.95"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="3.28"/>
                    <measurement group_id="O2" value="-2.8" spread="4.26"/>
                    <measurement group_id="O3" value="-2.8" spread="2.99"/>
                    <measurement group_id="O4" value="-1.2" spread="4.29"/>
                    <measurement group_id="O5" value="1.1" spread="4.08"/>
                    <measurement group_id="O6" value="-1.0" spread="3.58"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.5" spread="3.48"/>
                    <measurement group_id="O2" value="-3.3" spread="3.01"/>
                    <measurement group_id="O3" value="-0.8" spread="5.19"/>
                    <measurement group_id="O4" value="-1.4" spread="3.09"/>
                    <measurement group_id="O5" value="-0.1" spread="4.78"/>
                    <measurement group_id="O6" value="-1.0" spread="3.41"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="4.33"/>
                    <measurement group_id="O2" value="-0.8" spread="5.15"/>
                    <measurement group_id="O3" value="0.2" spread="4.54"/>
                    <measurement group_id="O4" value="-3.0" spread="3.94"/>
                    <measurement group_id="O5" value="1.4" spread="3.75"/>
                    <measurement group_id="O6" value="1.2" spread="3.37"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="2.67"/>
                    <measurement group_id="O2" value="-3.5" spread="4.59"/>
                    <measurement group_id="O3" value="-0.5" spread="3.62"/>
                    <measurement group_id="O4" value="-2.6" spread="3.71"/>
                    <measurement group_id="O5" value="2.7" spread="2.78"/>
                    <measurement group_id="O6" value="0.0" spread="2.10"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.3" spread="2.56"/>
                    <measurement group_id="O2" value="-1.8" spread="5.23"/>
                    <measurement group_id="O3" value="-1.7" spread="3.20"/>
                    <measurement group_id="O4" value="-2.0" spread="3.64"/>
                    <measurement group_id="O5" value="1.7" spread="3.50"/>
                    <measurement group_id="O6" value="1.5" spread="3.08"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.3" spread="3.79"/>
                    <measurement group_id="O2" value="-2.8" spread="4.54"/>
                    <measurement group_id="O3" value="-1.0" spread="3.35"/>
                    <measurement group_id="O4" value="-2.7" spread="3.04"/>
                    <measurement group_id="O5" value="0.6" spread="3.71"/>
                    <measurement group_id="O6" value="0.3" spread="2.73"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.5" spread="3.55"/>
                    <measurement group_id="O2" value="-3.5" spread="2.88"/>
                    <measurement group_id="O3" value="-2.3" spread="3.39"/>
                    <measurement group_id="O4" value="-3.7" spread="1.87"/>
                    <measurement group_id="O5" value="1.0" spread="2.40"/>
                    <measurement group_id="O6" value="0.3" spread="2.34"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="3.93"/>
                    <measurement group_id="O2" value="0.0" spread="3.63"/>
                    <measurement group_id="O3" value="0.3" spread="5.09"/>
                    <measurement group_id="O6" value="-0.7" spread="2.66"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="4.51"/>
                    <measurement group_id="O4" value="-2.6" spread="3.21"/>
                    <measurement group_id="O5" value="1.8" spread="3.77"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total protein, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.5" spread="3.54"/>
                    <measurement group_id="O6" value="0.7" spread="1.63"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.1" spread="2.68"/>
                    <measurement group_id="O2" value="-1.3" spread="2.42"/>
                    <measurement group_id="O3" value="-1.6" spread="2.07"/>
                    <measurement group_id="O4" value="-2.4" spread="2.01"/>
                    <measurement group_id="O5" value="-0.6" spread="3.36"/>
                    <measurement group_id="O6" value="-0.5" spread="3.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="2.70"/>
                    <measurement group_id="O2" value="-1.3" spread="1.97"/>
                    <measurement group_id="O3" value="-0.2" spread="2.48"/>
                    <measurement group_id="O4" value="-1.4" spread="2.83"/>
                    <measurement group_id="O5" value="-1.3" spread="2.06"/>
                    <measurement group_id="O6" value="-0.3" spread="2.07"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.3" spread="2.63"/>
                    <measurement group_id="O2" value="-0.5" spread="1.22"/>
                    <measurement group_id="O3" value="-0.7" spread="1.86"/>
                    <measurement group_id="O4" value="-2.2" spread="2.33"/>
                    <measurement group_id="O5" value="-1.4" spread="1.81"/>
                    <measurement group_id="O6" value="0.3" spread="2.16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.6" spread="1.68"/>
                    <measurement group_id="O2" value="-1.5" spread="1.87"/>
                    <measurement group_id="O3" value="-0.8" spread="3.54"/>
                    <measurement group_id="O4" value="-2.3" spread="2.50"/>
                    <measurement group_id="O5" value="-0.2" spread="3.49"/>
                    <measurement group_id="O6" value="-0.2" spread="2.56"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="2.34"/>
                    <measurement group_id="O2" value="-0.2" spread="2.86"/>
                    <measurement group_id="O3" value="0.0" spread="2.68"/>
                    <measurement group_id="O4" value="-2.2" spread="2.28"/>
                    <measurement group_id="O5" value="-1.4" spread="2.07"/>
                    <measurement group_id="O6" value="-1.4" spread="2.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="2.25"/>
                    <measurement group_id="O2" value="-0.2" spread="1.83"/>
                    <measurement group_id="O3" value="-1.7" spread="2.16"/>
                    <measurement group_id="O4" value="-0.8" spread="2.86"/>
                    <measurement group_id="O5" value="0.4" spread="1.88"/>
                    <measurement group_id="O6" value="-0.5" spread="1.52"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="2.42"/>
                    <measurement group_id="O2" value="-1.0" spread="2.28"/>
                    <measurement group_id="O3" value="-0.3" spread="2.88"/>
                    <measurement group_id="O4" value="-1.3" spread="1.87"/>
                    <measurement group_id="O5" value="-0.6" spread="2.19"/>
                    <measurement group_id="O6" value="-1.3" spread="2.73"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="2.73"/>
                    <measurement group_id="O2" value="-0.3" spread="2.88"/>
                    <measurement group_id="O3" value="0.7" spread="2.94"/>
                    <measurement group_id="O4" value="-2.0" spread="2.69"/>
                    <measurement group_id="O5" value="0.7" spread="2.83"/>
                    <measurement group_id="O6" value="0.7" spread="2.34"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="1.73"/>
                    <measurement group_id="O2" value="-1.3" spread="2.80"/>
                    <measurement group_id="O3" value="0.0" spread="2.45"/>
                    <measurement group_id="O4" value="-1.7" spread="2.40"/>
                    <measurement group_id="O5" value="0.4" spread="1.33"/>
                    <measurement group_id="O6" value="-0.2" spread="2.32"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="2.35"/>
                    <measurement group_id="O2" value="-0.3" spread="2.94"/>
                    <measurement group_id="O3" value="-1.5" spread="1.64"/>
                    <measurement group_id="O4" value="-0.7" spread="2.06"/>
                    <measurement group_id="O5" value="0.2" spread="2.44"/>
                    <measurement group_id="O6" value="0.2" spread="1.94"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="2.19"/>
                    <measurement group_id="O2" value="0.3" spread="2.73"/>
                    <measurement group_id="O3" value="-0.8" spread="2.32"/>
                    <measurement group_id="O4" value="-2.0" spread="1.87"/>
                    <measurement group_id="O5" value="0.4" spread="2.79"/>
                    <measurement group_id="O6" value="-0.2" spread="2.04"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.6" spread="2.27"/>
                    <measurement group_id="O2" value="-0.8" spread="1.72"/>
                    <measurement group_id="O3" value="-1.8" spread="2.93"/>
                    <measurement group_id="O4" value="-2.1" spread="0.60"/>
                    <measurement group_id="O5" value="0.1" spread="1.69"/>
                    <measurement group_id="O6" value="-0.3" spread="2.07"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="3.02"/>
                    <measurement group_id="O2" value="1.2" spread="3.06"/>
                    <measurement group_id="O3" value="-0.2" spread="2.93"/>
                    <measurement group_id="O6" value="-0.8" spread="2.14"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="2.94"/>
                    <measurement group_id="O4" value="-1.4" spread="1.67"/>
                    <measurement group_id="O5" value="0.6" spread="2.40"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Albumin, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="2.83"/>
                    <measurement group_id="O6" value="-0.3" spread="1.63"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Clinical Chemistry Parameters Like Total Bilirubin, Direct Bilirubin and Creatinine</title>
        <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like total bilirubin, direct bilirubin and creatinine. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Clinical Chemistry Parameters Like Total Bilirubin, Direct Bilirubin and Creatinine</title>
          <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like total bilirubin, direct bilirubin and creatinine. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Micromoles per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Total bilirubin, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="3.86"/>
                    <measurement group_id="O2" value="-1.3" spread="3.27"/>
                    <measurement group_id="O3" value="-1.6" spread="4.34"/>
                    <measurement group_id="O4" value="-0.2" spread="3.23"/>
                    <measurement group_id="O5" value="0.0" spread="5.20"/>
                    <measurement group_id="O6" value="1.0" spread="3.03"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.3" spread="3.45"/>
                    <measurement group_id="O2" value="-1.7" spread="3.44"/>
                    <measurement group_id="O3" value="-1.7" spread="4.97"/>
                    <measurement group_id="O4" value="0.2" spread="3.80"/>
                    <measurement group_id="O5" value="-0.4" spread="4.77"/>
                    <measurement group_id="O6" value="0.3" spread="2.34"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="3.13"/>
                    <measurement group_id="O2" value="-2.7" spread="5.01"/>
                    <measurement group_id="O3" value="-2.0" spread="7.48"/>
                    <measurement group_id="O4" value="0.0" spread="4.47"/>
                    <measurement group_id="O5" value="0.0" spread="4.47"/>
                    <measurement group_id="O6" value="1.0" spread="3.29"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.3" spread="4.58"/>
                    <measurement group_id="O2" value="-5.0" spread="5.76"/>
                    <measurement group_id="O3" value="-2.0" spread="3.58"/>
                    <measurement group_id="O4" value="-0.9" spread="5.49"/>
                    <measurement group_id="O5" value="-1.3" spread="2.45"/>
                    <measurement group_id="O6" value="-0.7" spread="3.27"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="4.82"/>
                    <measurement group_id="O2" value="-0.7" spread="4.50"/>
                    <measurement group_id="O3" value="1.7" spread="1.97"/>
                    <measurement group_id="O4" value="-1.1" spread="4.91"/>
                    <measurement group_id="O5" value="0.4" spread="3.84"/>
                    <measurement group_id="O6" value="-2.0" spread="2.83"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.2" spread="3.46"/>
                    <measurement group_id="O2" value="-2.3" spread="6.12"/>
                    <measurement group_id="O3" value="0.7" spread="2.73"/>
                    <measurement group_id="O4" value="2.2" spread="2.91"/>
                    <measurement group_id="O5" value="0.4" spread="5.55"/>
                    <measurement group_id="O6" value="0.7" spread="2.42"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="2.15"/>
                    <measurement group_id="O2" value="0.3" spread="2.34"/>
                    <measurement group_id="O3" value="0.3" spread="1.97"/>
                    <measurement group_id="O4" value="0.0" spread="2.45"/>
                    <measurement group_id="O5" value="-0.4" spread="5.81"/>
                    <measurement group_id="O6" value="1.0" spread="2.76"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.2" spread="4.04"/>
                    <measurement group_id="O2" value="-1.0" spread="6.29"/>
                    <measurement group_id="O3" value="2.0" spread="2.83"/>
                    <measurement group_id="O4" value="2.2" spread="4.06"/>
                    <measurement group_id="O5" value="0.4" spread="5.46"/>
                    <measurement group_id="O6" value="-1.0" spread="4.69"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.3" spread="4.03"/>
                    <measurement group_id="O2" value="0.0" spread="2.19"/>
                    <measurement group_id="O3" value="4.3" spread="5.85"/>
                    <measurement group_id="O4" value="-0.9" spread="2.03"/>
                    <measurement group_id="O5" value="0.0" spread="4.69"/>
                    <measurement group_id="O6" value="-0.7" spread="4.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="3.70"/>
                    <measurement group_id="O2" value="-1.3" spread="6.53"/>
                    <measurement group_id="O3" value="2.0" spread="2.83"/>
                    <measurement group_id="O4" value="0.7" spread="1.73"/>
                    <measurement group_id="O5" value="0.4" spread="6.23"/>
                    <measurement group_id="O6" value="-1.0" spread="3.52"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="4.47"/>
                    <measurement group_id="O2" value="-1.3" spread="3.27"/>
                    <measurement group_id="O3" value="1.7" spread="3.88"/>
                    <measurement group_id="O4" value="0.2" spread="2.54"/>
                    <measurement group_id="O5" value="1.6" spread="6.98"/>
                    <measurement group_id="O6" value="2.0" spread="4.56"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.3" spread="4.70"/>
                    <measurement group_id="O2" value="2.7" spread="3.93"/>
                    <measurement group_id="O3" value="0.3" spread="3.88"/>
                    <measurement group_id="O4" value="-0.2" spread="3.80"/>
                    <measurement group_id="O5" value="-0.7" spread="4.12"/>
                    <measurement group_id="O6" value="1.7" spread="2.34"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="2.07"/>
                    <measurement group_id="O2" value="-1.0" spread="5.62"/>
                    <measurement group_id="O3" value="0.0" spread="5.22"/>
                    <measurement group_id="O6" value="0.0" spread="4.90"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="7.12"/>
                    <measurement group_id="O4" value="0.4" spread="3.13"/>
                    <measurement group_id="O5" value="-1.1" spread="5.67"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Total bilirubin, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.0" spread="0.00"/>
                    <measurement group_id="O6" value="0.7" spread="2.07"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="1.15"/>
                    <measurement group_id="O2" value="-0.7" spread="1.03"/>
                    <measurement group_id="O3" value="-0.4" spread="0.89"/>
                    <measurement group_id="O4" value="-0.2" spread="1.20"/>
                    <measurement group_id="O5" value="0.2" spread="1.20"/>
                    <measurement group_id="O6" value="0.3" spread="0.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="0.90"/>
                    <measurement group_id="O2" value="-0.3" spread="0.82"/>
                    <measurement group_id="O3" value="-0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.4" spread="1.67"/>
                    <measurement group_id="O5" value="0.0" spread="1.00"/>
                    <measurement group_id="O6" value="0.0" spread="1.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="0.90"/>
                    <measurement group_id="O2" value="-0.3" spread="0.82"/>
                    <measurement group_id="O3" value="-0.7" spread="1.03"/>
                    <measurement group_id="O4" value="0.2" spread="1.56"/>
                    <measurement group_id="O5" value="0.2" spread="1.20"/>
                    <measurement group_id="O6" value="-0.3" spread="0.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="0.98"/>
                    <measurement group_id="O2" value="-0.7" spread="1.03"/>
                    <measurement group_id="O3" value="-0.7" spread="1.03"/>
                    <measurement group_id="O4" value="0.2" spread="1.56"/>
                    <measurement group_id="O5" value="0.0" spread="1.00"/>
                    <measurement group_id="O6" value="-0.7" spread="1.03"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="0.93"/>
                    <measurement group_id="O2" value="-0.3" spread="0.82"/>
                    <measurement group_id="O3" value="-0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.0" spread="1.41"/>
                    <measurement group_id="O5" value="0.0" spread="1.00"/>
                    <measurement group_id="O6" value="-0.8" spread="1.10"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="1.15"/>
                    <measurement group_id="O2" value="0.0" spread="0.00"/>
                    <measurement group_id="O3" value="0.0" spread="0.00"/>
                    <measurement group_id="O4" value="0.7" spread="1.41"/>
                    <measurement group_id="O5" value="0.2" spread="1.20"/>
                    <measurement group_id="O6" value="0.3" spread="1.51"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="0.85"/>
                    <measurement group_id="O2" value="0.0" spread="1.26"/>
                    <measurement group_id="O3" value="0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.2" spread="1.20"/>
                    <measurement group_id="O5" value="0.2" spread="1.20"/>
                    <measurement group_id="O6" value="0.0" spread="1.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="1.03"/>
                    <measurement group_id="O2" value="0.0" spread="0.00"/>
                    <measurement group_id="O3" value="0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.9" spread="1.45"/>
                    <measurement group_id="O5" value="0.4" spread="1.33"/>
                    <measurement group_id="O6" value="-0.7" spread="1.03"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="0.90"/>
                    <measurement group_id="O2" value="0.0" spread="1.26"/>
                    <measurement group_id="O3" value="0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.2" spread="1.20"/>
                    <measurement group_id="O5" value="0.2" spread="1.20"/>
                    <measurement group_id="O6" value="-0.3" spread="1.51"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="1.03"/>
                    <measurement group_id="O2" value="0.0" spread="1.26"/>
                    <measurement group_id="O3" value="0.0" spread="0.00"/>
                    <measurement group_id="O4" value="0.7" spread="1.00"/>
                    <measurement group_id="O5" value="0.4" spread="1.33"/>
                    <measurement group_id="O6" value="0.0" spread="1.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="0.78"/>
                    <measurement group_id="O2" value="0.3" spread="1.51"/>
                    <measurement group_id="O3" value="-0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.2" spread="1.20"/>
                    <measurement group_id="O5" value="0.9" spread="1.76"/>
                    <measurement group_id="O6" value="0.0" spread="1.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="1.21"/>
                    <measurement group_id="O2" value="0.7" spread="1.03"/>
                    <measurement group_id="O3" value="0.3" spread="0.82"/>
                    <measurement group_id="O4" value="0.0" spread="1.41"/>
                    <measurement group_id="O5" value="0.0" spread="1.00"/>
                    <measurement group_id="O6" value="0.0" spread="1.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="0.82"/>
                    <measurement group_id="O2" value="-0.3" spread="0.82"/>
                    <measurement group_id="O3" value="-0.3" spread="1.51"/>
                    <measurement group_id="O6" value="0.0" spread="1.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="1.79"/>
                    <measurement group_id="O4" value="0.0" spread="1.00"/>
                    <measurement group_id="O5" value="0.4" spread="1.67"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Direct bilirubin, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="1.41"/>
                    <measurement group_id="O6" value="-0.3" spread="0.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.80" spread="5.501"/>
                    <measurement group_id="O2" value="-1.03" spread="3.930"/>
                    <measurement group_id="O3" value="-1.42" spread="3.512"/>
                    <measurement group_id="O4" value="-4.91" spread="4.835"/>
                    <measurement group_id="O5" value="-0.77" spread="4.863"/>
                    <measurement group_id="O6" value="-1.63" spread="6.417"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.48" spread="6.036"/>
                    <measurement group_id="O2" value="-1.78" spread="3.571"/>
                    <measurement group_id="O3" value="-2.95" spread="6.208"/>
                    <measurement group_id="O4" value="-1.58" spread="4.913"/>
                    <measurement group_id="O5" value="-1.87" spread="5.026"/>
                    <measurement group_id="O6" value="-1.20" spread="3.795"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.29" spread="6.544"/>
                    <measurement group_id="O2" value="-0.73" spread="4.126"/>
                    <measurement group_id="O3" value="-0.75" spread="7.123"/>
                    <measurement group_id="O4" value="-4.64" spread="6.296"/>
                    <measurement group_id="O5" value="-0.88" spread="3.180"/>
                    <measurement group_id="O6" value="3.68" spread="7.962"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.73" spread="5.166"/>
                    <measurement group_id="O2" value="0.72" spread="1.883"/>
                    <measurement group_id="O3" value="-2.53" spread="4.541"/>
                    <measurement group_id="O4" value="-4.63" spread="6.355"/>
                    <measurement group_id="O5" value="0.39" spread="3.085"/>
                    <measurement group_id="O6" value="-1.62" spread="5.216"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.49" spread="7.084"/>
                    <measurement group_id="O2" value="3.68" spread="4.892"/>
                    <measurement group_id="O3" value="-2.08" spread="6.098"/>
                    <measurement group_id="O4" value="-3.06" spread="6.393"/>
                    <measurement group_id="O5" value="0.59" spread="4.303"/>
                    <measurement group_id="O6" value="-0.70" spread="7.736"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.12" spread="5.854"/>
                    <measurement group_id="O2" value="1.47" spread="5.019"/>
                    <measurement group_id="O3" value="-0.90" spread="6.377"/>
                    <measurement group_id="O4" value="-2.67" spread="5.702"/>
                    <measurement group_id="O5" value="2.27" spread="5.322"/>
                    <measurement group_id="O6" value="0.73" spread="7.868"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.28" spread="4.730"/>
                    <measurement group_id="O2" value="-2.80" spread="3.839"/>
                    <measurement group_id="O3" value="0.27" spread="3.837"/>
                    <measurement group_id="O4" value="0.09" spread="6.843"/>
                    <measurement group_id="O5" value="0.59" spread="5.989"/>
                    <measurement group_id="O6" value="6.05" spread="6.066"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.40" spread="6.462"/>
                    <measurement group_id="O2" value="0.28" spread="5.062"/>
                    <measurement group_id="O3" value="-1.20" spread="7.277"/>
                    <measurement group_id="O4" value="0.19" spread="3.718"/>
                    <measurement group_id="O5" value="6.00" spread="4.511"/>
                    <measurement group_id="O6" value="1.63" spread="4.317"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.30" spread="7.643"/>
                    <measurement group_id="O2" value="0.88" spread="5.043"/>
                    <measurement group_id="O3" value="1.03" spread="5.846"/>
                    <measurement group_id="O4" value="-0.41" spread="4.748"/>
                    <measurement group_id="O5" value="5.01" spread="3.820"/>
                    <measurement group_id="O6" value="0.72" spread="4.532"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.27" spread="7.753"/>
                    <measurement group_id="O2" value="1.75" spread="4.831"/>
                    <measurement group_id="O3" value="2.05" spread="7.131"/>
                    <measurement group_id="O4" value="2.83" spread="5.033"/>
                    <measurement group_id="O5" value="4.42" spread="5.191"/>
                    <measurement group_id="O6" value="1.15" spread="6.297"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.89" spread="4.393"/>
                    <measurement group_id="O2" value="1.77" spread="5.597"/>
                    <measurement group_id="O3" value="1.60" spread="5.877"/>
                    <measurement group_id="O4" value="7.07" spread="6.581"/>
                    <measurement group_id="O5" value="2.66" spread="6.005"/>
                    <measurement group_id="O6" value="2.20" spread="4.431"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.29" spread="5.633"/>
                    <measurement group_id="O2" value="-2.22" spread="5.017"/>
                    <measurement group_id="O3" value="0.27" spread="15.342"/>
                    <measurement group_id="O4" value="3.16" spread="6.620"/>
                    <measurement group_id="O5" value="0.69" spread="3.857"/>
                    <measurement group_id="O6" value="3.22" spread="5.653"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.00" spread="5.871"/>
                    <measurement group_id="O2" value="0.87" spread="5.904"/>
                    <measurement group_id="O3" value="6.60" spread="6.880"/>
                    <measurement group_id="O6" value="2.05" spread="2.474"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.60" spread="4.767"/>
                    <measurement group_id="O4" value="2.57" spread="4.347"/>
                    <measurement group_id="O5" value="10.42" spread="6.864"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.75" spread="2.475"/>
                    <measurement group_id="O6" value="1.60" spread="6.174"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Urine Specific Gravity Analysis by Dipstick Method</title>
        <description>Urinary specific gravity measurement is a routine part of urinalysis. Urine specific gravity is a measure of the concentration of solutes in the urine and provides information on the kidney's ability to concentrate urine. The concentration of the excreted molecules determines the urine's specific gravity.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Urine Specific Gravity Analysis by Dipstick Method</title>
          <description>Urinary specific gravity measurement is a routine part of urinalysis. Urine specific gravity is a measure of the concentration of solutes in the urine and provides information on the kidney's ability to concentrate urine. The concentration of the excreted molecules determines the urine's specific gravity.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Ratio</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="3"/>
                <count group_id="O2" value="2"/>
                <count group_id="O3" value="1"/>
                <count group_id="O4" value="5"/>
                <count group_id="O5" value="1"/>
                <count group_id="O6" value="1"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=1,2,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0200" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O2" value="1.0125" spread="0.00354"/>
                    <measurement group_id="O4" value="1.0120" spread="0.00283"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=2,0,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0265" spread="0.00212"/>
                    <measurement group_id="O4" value="1.0280" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=0,0,1,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O3" value="1.0150" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0290" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=2,0,0,2,1,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="1"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0275" spread="0.00354"/>
                    <measurement group_id="O4" value="1.0205" spread="0.00919"/>
                    <measurement group_id="O5" value="1.0140" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=2,1,1,3,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0235" spread="0.00212"/>
                    <measurement group_id="O2" value="1.0260" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O3" value="1.0250" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0197" spread="0.00751"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=1,0,0,4,1,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="1"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0250" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0218" spread="0.00822"/>
                    <measurement group_id="O5" value="1.0130" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=3,1,1,5,0,1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="3"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0193" spread="0.00839"/>
                    <measurement group_id="O2" value="1.0150" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O3" value="1.0250" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0158" spread="0.01052"/>
                    <measurement group_id="O6" value="1.0270" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=1,0,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0300" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0220" spread="0.00566"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=0,1,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="1.0180" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0230" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=3,1,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="3"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0260" spread="0.00265"/>
                    <measurement group_id="O2" value="1.0180" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0230" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=1,1,0,4,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0200" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O2" value="1.0230" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="1.0200" spread="0.00374"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=0,0,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O4" value="1.0240" spread="0.00566"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=1,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0150" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=0,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
            </class>
            <class>
              <title>Week 40,n=0,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP)</title>
        <description>SBP and DBP were assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP)</title>
          <description>SBP and DBP were assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Millimeters of mercury</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>SBP, 2 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="6.08"/>
                    <measurement group_id="O2" value="-2.2" spread="7.47"/>
                    <measurement group_id="O3" value="3.3" spread="7.37"/>
                    <measurement group_id="O4" value="-0.9" spread="7.18"/>
                    <measurement group_id="O5" value="-1.8" spread="7.19"/>
                    <measurement group_id="O6" value="-2.0" spread="8.58"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, 8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="6.00"/>
                    <measurement group_id="O2" value="4.2" spread="10.01"/>
                    <measurement group_id="O3" value="3.0" spread="8.46"/>
                    <measurement group_id="O4" value="1.7" spread="10.69"/>
                    <measurement group_id="O5" value="4.9" spread="7.52"/>
                    <measurement group_id="O6" value="-2.2" spread="5.64"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.5" spread="7.00"/>
                    <measurement group_id="O2" value="-0.8" spread="8.08"/>
                    <measurement group_id="O3" value="6.0" spread="4.86"/>
                    <measurement group_id="O4" value="1.8" spread="9.11"/>
                    <measurement group_id="O5" value="6.3" spread="7.42"/>
                    <measurement group_id="O6" value="-5.3" spread="4.37"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.6" spread="9.21"/>
                    <measurement group_id="O2" value="-2.2" spread="7.36"/>
                    <measurement group_id="O3" value="3.7" spread="9.16"/>
                    <measurement group_id="O4" value="1.0" spread="10.68"/>
                    <measurement group_id="O5" value="-0.1" spread="4.43"/>
                    <measurement group_id="O6" value="-5.0" spread="6.00"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.8" spread="5.75"/>
                    <measurement group_id="O2" value="-2.2" spread="6.24"/>
                    <measurement group_id="O3" value="2.3" spread="8.09"/>
                    <measurement group_id="O4" value="0.3" spread="6.91"/>
                    <measurement group_id="O5" value="2.9" spread="6.86"/>
                    <measurement group_id="O6" value="-3.3" spread="7.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.0" spread="6.05"/>
                    <measurement group_id="O2" value="0.8" spread="6.82"/>
                    <measurement group_id="O3" value="1.0" spread="7.72"/>
                    <measurement group_id="O4" value="-2.8" spread="9.81"/>
                    <measurement group_id="O5" value="0.4" spread="3.91"/>
                    <measurement group_id="O6" value="-4.7" spread="4.46"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="8.86"/>
                    <measurement group_id="O2" value="0.3" spread="7.50"/>
                    <measurement group_id="O3" value="1.5" spread="6.60"/>
                    <measurement group_id="O4" value="-2.7" spread="9.06"/>
                    <measurement group_id="O5" value="1.7" spread="5.02"/>
                    <measurement group_id="O6" value="0.2" spread="8.13"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.6" spread="5.90"/>
                    <measurement group_id="O2" value="1.0" spread="10.22"/>
                    <measurement group_id="O3" value="5.8" spread="5.85"/>
                    <measurement group_id="O4" value="4.2" spread="10.45"/>
                    <measurement group_id="O5" value="0.8" spread="11.04"/>
                    <measurement group_id="O6" value="-2.8" spread="9.83"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.6" spread="8.80"/>
                    <measurement group_id="O2" value="0.3" spread="8.82"/>
                    <measurement group_id="O3" value="7.0" spread="11.26"/>
                    <measurement group_id="O4" value="3.2" spread="14.09"/>
                    <measurement group_id="O5" value="0.9" spread="6.11"/>
                    <measurement group_id="O6" value="-2.3" spread="7.15"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="9.71"/>
                    <measurement group_id="O2" value="0.0" spread="9.27"/>
                    <measurement group_id="O3" value="2.0" spread="12.66"/>
                    <measurement group_id="O4" value="3.1" spread="8.52"/>
                    <measurement group_id="O5" value="-1.4" spread="6.60"/>
                    <measurement group_id="O6" value="-1.8" spread="5.91"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="5.13"/>
                    <measurement group_id="O2" value="1.2" spread="5.19"/>
                    <measurement group_id="O3" value="2.3" spread="9.97"/>
                    <measurement group_id="O4" value="5.4" spread="9.41"/>
                    <measurement group_id="O5" value="0.0" spread="7.37"/>
                    <measurement group_id="O6" value="-4.2" spread="11.18"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="6.86"/>
                    <measurement group_id="O2" value="4.2" spread="9.15"/>
                    <measurement group_id="O3" value="3.8" spread="13.33"/>
                    <measurement group_id="O4" value="2.0" spread="8.76"/>
                    <measurement group_id="O5" value="2.1" spread="9.52"/>
                    <measurement group_id="O6" value="-7.3" spread="15.49"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="8.22"/>
                    <measurement group_id="O2" value="9.3" spread="10.42"/>
                    <measurement group_id="O3" value="3.7" spread="6.59"/>
                    <measurement group_id="O4" value="2.9" spread="9.91"/>
                    <measurement group_id="O5" value="1.9" spread="12.06"/>
                    <measurement group_id="O6" value="-2.2" spread="6.46"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.0" spread="11.95"/>
                    <measurement group_id="O2" value="3.2" spread="6.11"/>
                    <measurement group_id="O3" value="3.2" spread="5.91"/>
                    <measurement group_id="O4" value="7.9" spread="10.13"/>
                    <measurement group_id="O5" value="2.9" spread="7.56"/>
                    <measurement group_id="O6" value="-5.8" spread="6.11"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.0" spread="6.90"/>
                    <measurement group_id="O2" value="-3.8" spread="12.45"/>
                    <measurement group_id="O3" value="8.7" spread="10.61"/>
                    <measurement group_id="O6" value="-3.3" spread="6.89"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.5" spread="13.72"/>
                    <measurement group_id="O4" value="2.8" spread="9.59"/>
                    <measurement group_id="O5" value="2.8" spread="7.77"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SBP, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-15.0" spread="14.14"/>
                    <measurement group_id="O6" value="-5.8" spread="17.52"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, 2 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.9" spread="5.00"/>
                    <measurement group_id="O2" value="3.3" spread="4.89"/>
                    <measurement group_id="O3" value="4.3" spread="9.14"/>
                    <measurement group_id="O4" value="-2.2" spread="4.18"/>
                    <measurement group_id="O5" value="-2.2" spread="6.14"/>
                    <measurement group_id="O6" value="-3.8" spread="1.94"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, 8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="4.34"/>
                    <measurement group_id="O2" value="2.0" spread="7.46"/>
                    <measurement group_id="O3" value="0.5" spread="9.52"/>
                    <measurement group_id="O4" value="-1.3" spread="4.58"/>
                    <measurement group_id="O5" value="-2.0" spread="5.74"/>
                    <measurement group_id="O6" value="-1.8" spread="5.56"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="4.47"/>
                    <measurement group_id="O2" value="0.8" spread="4.49"/>
                    <measurement group_id="O3" value="3.0" spread="5.83"/>
                    <measurement group_id="O4" value="-1.1" spread="5.67"/>
                    <measurement group_id="O5" value="4.7" spread="4.18"/>
                    <measurement group_id="O6" value="0.0" spread="4.94"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.6" spread="3.99"/>
                    <measurement group_id="O2" value="-1.3" spread="7.26"/>
                    <measurement group_id="O3" value="3.0" spread="7.04"/>
                    <measurement group_id="O4" value="-2.6" spread="5.41"/>
                    <measurement group_id="O5" value="-0.3" spread="4.30"/>
                    <measurement group_id="O6" value="-0.3" spread="6.44"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="5.04"/>
                    <measurement group_id="O2" value="2.3" spread="4.80"/>
                    <measurement group_id="O3" value="-1.0" spread="5.69"/>
                    <measurement group_id="O4" value="-0.2" spread="5.14"/>
                    <measurement group_id="O5" value="0.1" spread="3.76"/>
                    <measurement group_id="O6" value="-2.8" spread="3.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.4" spread="4.40"/>
                    <measurement group_id="O2" value="4.8" spread="6.49"/>
                    <measurement group_id="O3" value="0.7" spread="8.09"/>
                    <measurement group_id="O4" value="-4.1" spread="7.29"/>
                    <measurement group_id="O5" value="0.9" spread="4.23"/>
                    <measurement group_id="O6" value="-1.5" spread="2.81"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.6" spread="5.37"/>
                    <measurement group_id="O2" value="3.7" spread="6.98"/>
                    <measurement group_id="O3" value="4.3" spread="9.27"/>
                    <measurement group_id="O4" value="-0.4" spread="5.68"/>
                    <measurement group_id="O5" value="0.8" spread="3.38"/>
                    <measurement group_id="O6" value="0.0" spread="5.44"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="6.23"/>
                    <measurement group_id="O2" value="4.7" spread="5.65"/>
                    <measurement group_id="O3" value="6.0" spread="8.99"/>
                    <measurement group_id="O4" value="1.6" spread="4.36"/>
                    <measurement group_id="O5" value="1.9" spread="6.92"/>
                    <measurement group_id="O6" value="0.2" spread="4.62"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="6.17"/>
                    <measurement group_id="O2" value="1.3" spread="7.74"/>
                    <measurement group_id="O3" value="4.2" spread="11.36"/>
                    <measurement group_id="O4" value="3.1" spread="6.09"/>
                    <measurement group_id="O5" value="1.6" spread="5.41"/>
                    <measurement group_id="O6" value="3.8" spread="4.40"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.3" spread="3.73"/>
                    <measurement group_id="O2" value="5.2" spread="5.49"/>
                    <measurement group_id="O3" value="5.5" spread="13.28"/>
                    <measurement group_id="O4" value="3.3" spread="4.95"/>
                    <measurement group_id="O5" value="0.7" spread="4.21"/>
                    <measurement group_id="O6" value="0.5" spread="3.94"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.9" spread="6.29"/>
                    <measurement group_id="O2" value="3.2" spread="5.91"/>
                    <measurement group_id="O3" value="1.7" spread="14.15"/>
                    <measurement group_id="O4" value="3.4" spread="5.39"/>
                    <measurement group_id="O5" value="3.6" spread="4.72"/>
                    <measurement group_id="O6" value="1.3" spread="5.09"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.1" spread="6.63"/>
                    <measurement group_id="O2" value="3.3" spread="5.68"/>
                    <measurement group_id="O3" value="3.0" spread="12.65"/>
                    <measurement group_id="O4" value="0.7" spread="6.84"/>
                    <measurement group_id="O5" value="3.8" spread="8.07"/>
                    <measurement group_id="O6" value="0.5" spread="7.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.6" spread="7.77"/>
                    <measurement group_id="O2" value="6.3" spread="5.35"/>
                    <measurement group_id="O3" value="4.0" spread="9.78"/>
                    <measurement group_id="O4" value="5.3" spread="6.56"/>
                    <measurement group_id="O5" value="1.1" spread="9.12"/>
                    <measurement group_id="O6" value="2.0" spread="5.66"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="7.23"/>
                    <measurement group_id="O2" value="3.2" spread="4.36"/>
                    <measurement group_id="O3" value="3.8" spread="9.45"/>
                    <measurement group_id="O4" value="6.6" spread="8.38"/>
                    <measurement group_id="O5" value="1.8" spread="8.61"/>
                    <measurement group_id="O6" value="0.2" spread="3.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.3" spread="2.34"/>
                    <measurement group_id="O2" value="-0.2" spread="6.49"/>
                    <measurement group_id="O3" value="7.0" spread="4.34"/>
                    <measurement group_id="O6" value="2.0" spread="7.64"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3" spread="13.13"/>
                    <measurement group_id="O4" value="3.6" spread="5.64"/>
                    <measurement group_id="O5" value="2.3" spread="8.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>DBP, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="4.95"/>
                    <measurement group_id="O6" value="-3.5" spread="6.95"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Temperature</title>
        <description>Temperature was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Temperature</title>
          <description>Temperature was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Degree Celsius</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>2 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.05" spread="0.419"/>
                    <measurement group_id="O2" value="0.32" spread="0.293"/>
                    <measurement group_id="O3" value="0.13" spread="0.163"/>
                    <measurement group_id="O4" value="0.30" spread="0.474"/>
                    <measurement group_id="O5" value="0.03" spread="0.328"/>
                    <measurement group_id="O6" value="0.00" spread="0.420"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Category title 2. 8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.13" spread="0.405"/>
                    <measurement group_id="O2" value="0.40" spread="0.410"/>
                    <measurement group_id="O3" value="0.07" spread="0.234"/>
                    <measurement group_id="O4" value="0.24" spread="0.513"/>
                    <measurement group_id="O5" value="0.18" spread="0.291"/>
                    <measurement group_id="O6" value="0.35" spread="0.589"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Category title 3. Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.01" spread="0.312"/>
                    <measurement group_id="O2" value="0.23" spread="0.437"/>
                    <measurement group_id="O3" value="0.10" spread="0.429"/>
                    <measurement group_id="O4" value="-0.03" spread="0.559"/>
                    <measurement group_id="O5" value="-0.01" spread="0.333"/>
                    <measurement group_id="O6" value="-0.05" spread="0.259"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.10" spread="0.402"/>
                    <measurement group_id="O2" value="0.02" spread="0.538"/>
                    <measurement group_id="O3" value="0.02" spread="0.256"/>
                    <measurement group_id="O4" value="0.13" spread="0.439"/>
                    <measurement group_id="O5" value="0.02" spread="0.315"/>
                    <measurement group_id="O6" value="0.12" spread="0.343"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.03" spread="0.260"/>
                    <measurement group_id="O2" value="0.15" spread="0.554"/>
                    <measurement group_id="O3" value="0.08" spread="0.293"/>
                    <measurement group_id="O4" value="0.11" spread="0.382"/>
                    <measurement group_id="O5" value="0.22" spread="0.239"/>
                    <measurement group_id="O6" value="0.02" spread="0.397"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.08" spread="0.171"/>
                    <measurement group_id="O2" value="0.13" spread="0.516"/>
                    <measurement group_id="O3" value="0.25" spread="0.464"/>
                    <measurement group_id="O4" value="-0.07" spread="0.300"/>
                    <measurement group_id="O5" value="-0.04" spread="0.255"/>
                    <measurement group_id="O6" value="0.12" spread="0.293"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.13" spread="0.293"/>
                    <measurement group_id="O2" value="0.32" spread="0.492"/>
                    <measurement group_id="O3" value="0.18" spread="0.147"/>
                    <measurement group_id="O4" value="0.12" spread="0.399"/>
                    <measurement group_id="O5" value="0.01" spread="0.359"/>
                    <measurement group_id="O6" value="0.18" spread="0.232"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.29" spread="0.448"/>
                    <measurement group_id="O2" value="0.30" spread="0.460"/>
                    <measurement group_id="O3" value="0.03" spread="0.333"/>
                    <measurement group_id="O4" value="0.04" spread="0.340"/>
                    <measurement group_id="O5" value="0.08" spread="0.441"/>
                    <measurement group_id="O6" value="-0.08" spread="0.319"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.23" spread="0.172"/>
                    <measurement group_id="O2" value="0.20" spread="0.400"/>
                    <measurement group_id="O3" value="-0.02" spread="0.387"/>
                    <measurement group_id="O4" value="-0.09" spread="0.302"/>
                    <measurement group_id="O5" value="0.00" spread="0.671"/>
                    <measurement group_id="O6" value="-0.03" spread="0.258"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.00" spread="0.280"/>
                    <measurement group_id="O2" value="0.32" spread="0.397"/>
                    <measurement group_id="O3" value="-0.18" spread="0.504"/>
                    <measurement group_id="O4" value="0.09" spread="0.446"/>
                    <measurement group_id="O5" value="0.02" spread="0.282"/>
                    <measurement group_id="O6" value="0.13" spread="0.197"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.10" spread="0.386"/>
                    <measurement group_id="O2" value="0.17" spread="0.356"/>
                    <measurement group_id="O3" value="-0.15" spread="0.187"/>
                    <measurement group_id="O4" value="0.09" spread="0.337"/>
                    <measurement group_id="O5" value="-0.09" spread="0.355"/>
                    <measurement group_id="O6" value="0.00" spread="0.369"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.07" spread="0.267"/>
                    <measurement group_id="O2" value="0.18" spread="0.662"/>
                    <measurement group_id="O3" value="0.02" spread="0.407"/>
                    <measurement group_id="O4" value="0.13" spread="0.512"/>
                    <measurement group_id="O5" value="0.07" spread="0.283"/>
                    <measurement group_id="O6" value="-0.05" spread="0.399"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.07" spread="0.396"/>
                    <measurement group_id="O2" value="0.08" spread="0.488"/>
                    <measurement group_id="O3" value="0.08" spread="0.319"/>
                    <measurement group_id="O4" value="-0.02" spread="0.367"/>
                    <measurement group_id="O5" value="-0.07" spread="0.316"/>
                    <measurement group_id="O6" value="-0.02" spread="0.133"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.08" spread="0.311"/>
                    <measurement group_id="O2" value="0.03" spread="0.441"/>
                    <measurement group_id="O3" value="-0.02" spread="0.504"/>
                    <measurement group_id="O4" value="0.08" spread="0.424"/>
                    <measurement group_id="O5" value="0.00" spread="0.442"/>
                    <measurement group_id="O6" value="-0.22" spread="0.117"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.30" spread="0.569"/>
                    <measurement group_id="O2" value="0.48" spread="1.363"/>
                    <measurement group_id="O3" value="0.02" spread="0.306"/>
                    <measurement group_id="O6" value="0.08" spread="0.331"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.22" spread="0.366"/>
                    <measurement group_id="O4" value="0.14" spread="0.433"/>
                    <measurement group_id="O5" value="-0.03" spread="0.212"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.10" spread="0.566"/>
                    <measurement group_id="O6" value="-0.05" spread="0.084"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Heart Rate</title>
        <description>Heart rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Heart Rate</title>
          <description>Heart rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Beats per minute</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>2 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.2" spread="13.62"/>
                    <measurement group_id="O2" value="-4.2" spread="5.27"/>
                    <measurement group_id="O3" value="-3.3" spread="8.64"/>
                    <measurement group_id="O4" value="0.8" spread="14.45"/>
                    <measurement group_id="O5" value="0.9" spread="10.74"/>
                    <measurement group_id="O6" value="5.2" spread="5.46"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="7.05"/>
                    <measurement group_id="O2" value="-2.0" spread="7.27"/>
                    <measurement group_id="O3" value="-3.2" spread="3.37"/>
                    <measurement group_id="O4" value="0.3" spread="14.21"/>
                    <measurement group_id="O5" value="1.0" spread="11.62"/>
                    <measurement group_id="O6" value="4.8" spread="8.06"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.2" spread="6.59"/>
                    <measurement group_id="O2" value="-1.5" spread="2.81"/>
                    <measurement group_id="O3" value="-1.7" spread="3.83"/>
                    <measurement group_id="O4" value="-4.0" spread="11.03"/>
                    <measurement group_id="O5" value="2.7" spread="8.14"/>
                    <measurement group_id="O6" value="-0.7" spread="3.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="4.82"/>
                    <measurement group_id="O2" value="0.2" spread="5.88"/>
                    <measurement group_id="O3" value="1.3" spread="8.41"/>
                    <measurement group_id="O4" value="0.7" spread="4.92"/>
                    <measurement group_id="O5" value="4.7" spread="3.94"/>
                    <measurement group_id="O6" value="-1.0" spread="7.40"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.8" spread="7.53"/>
                    <measurement group_id="O2" value="1.7" spread="4.84"/>
                    <measurement group_id="O3" value="4.7" spread="8.98"/>
                    <measurement group_id="O4" value="-1.2" spread="11.62"/>
                    <measurement group_id="O5" value="3.6" spread="5.27"/>
                    <measurement group_id="O6" value="1.5" spread="3.33"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="4.91"/>
                    <measurement group_id="O2" value="2.8" spread="8.61"/>
                    <measurement group_id="O3" value="1.2" spread="7.83"/>
                    <measurement group_id="O4" value="-0.1" spread="10.30"/>
                    <measurement group_id="O5" value="0.6" spread="4.28"/>
                    <measurement group_id="O6" value="3.0" spread="4.47"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="6.03"/>
                    <measurement group_id="O2" value="0.0" spread="10.58"/>
                    <measurement group_id="O3" value="-1.8" spread="7.05"/>
                    <measurement group_id="O4" value="-1.1" spread="10.80"/>
                    <measurement group_id="O5" value="1.4" spread="5.98"/>
                    <measurement group_id="O6" value="5.0" spread="9.21"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.8" spread="5.57"/>
                    <measurement group_id="O2" value="-1.3" spread="5.89"/>
                    <measurement group_id="O3" value="-5.2" spread="5.23"/>
                    <measurement group_id="O4" value="2.1" spread="12.38"/>
                    <measurement group_id="O5" value="1.0" spread="10.51"/>
                    <measurement group_id="O6" value="2.0" spread="6.00"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.2" spread="8.46"/>
                    <measurement group_id="O2" value="-2.3" spread="2.88"/>
                    <measurement group_id="O3" value="-1.5" spread="5.96"/>
                    <measurement group_id="O4" value="-1.1" spread="10.54"/>
                    <measurement group_id="O5" value="0.8" spread="13.58"/>
                    <measurement group_id="O6" value="0.5" spread="9.35"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="7.12"/>
                    <measurement group_id="O2" value="-1.8" spread="7.14"/>
                    <measurement group_id="O3" value="-3.7" spread="5.79"/>
                    <measurement group_id="O4" value="-4.9" spread="15.39"/>
                    <measurement group_id="O5" value="-0.6" spread="6.52"/>
                    <measurement group_id="O6" value="-0.3" spread="4.72"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.2" spread="10.47"/>
                    <measurement group_id="O2" value="3.3" spread="8.38"/>
                    <measurement group_id="O3" value="-2.3" spread="6.53"/>
                    <measurement group_id="O4" value="0.6" spread="16.41"/>
                    <measurement group_id="O5" value="1.0" spread="9.31"/>
                    <measurement group_id="O6" value="3.0" spread="7.38"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.2" spread="8.56"/>
                    <measurement group_id="O2" value="-2.0" spread="7.07"/>
                    <measurement group_id="O3" value="-1.7" spread="5.50"/>
                    <measurement group_id="O4" value="0.8" spread="10.84"/>
                    <measurement group_id="O5" value="1.7" spread="9.10"/>
                    <measurement group_id="O6" value="2.5" spread="7.23"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.4" spread="10.03"/>
                    <measurement group_id="O2" value="-0.8" spread="6.85"/>
                    <measurement group_id="O3" value="1.8" spread="7.68"/>
                    <measurement group_id="O4" value="-2.8" spread="12.04"/>
                    <measurement group_id="O5" value="3.2" spread="9.28"/>
                    <measurement group_id="O6" value="0.0" spread="4.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="10.04"/>
                    <measurement group_id="O2" value="-0.2" spread="2.56"/>
                    <measurement group_id="O3" value="-0.7" spread="6.59"/>
                    <measurement group_id="O4" value="2.0" spread="12.03"/>
                    <measurement group_id="O5" value="1.6" spread="7.09"/>
                    <measurement group_id="O6" value="1.8" spread="4.58"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="10.55"/>
                    <measurement group_id="O2" value="-2.2" spread="5.19"/>
                    <measurement group_id="O3" value="0.7" spread="6.06"/>
                    <measurement group_id="O6" value="0.8" spread="7.28"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="11.59"/>
                    <measurement group_id="O4" value="0.0" spread="12.50"/>
                    <measurement group_id="O5" value="2.6" spread="6.29"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="2.83"/>
                    <measurement group_id="O6" value="2.8" spread="10.26"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Respiration Rate</title>
        <description>Respiration rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Respiration Rate</title>
          <description>Respiration rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Breaths per minute</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>2 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.8" spread="2.42"/>
                    <measurement group_id="O2" value="1.2" spread="1.83"/>
                    <measurement group_id="O3" value="0.0" spread="2.53"/>
                    <measurement group_id="O4" value="0.3" spread="2.65"/>
                    <measurement group_id="O5" value="0.8" spread="1.72"/>
                    <measurement group_id="O6" value="2.2" spread="3.31"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="2.19"/>
                    <measurement group_id="O2" value="0.5" spread="3.27"/>
                    <measurement group_id="O3" value="-1.0" spread="1.79"/>
                    <measurement group_id="O4" value="1.0" spread="3.28"/>
                    <measurement group_id="O5" value="2.1" spread="1.83"/>
                    <measurement group_id="O6" value="0.3" spread="1.63"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="2.64"/>
                    <measurement group_id="O2" value="1.7" spread="2.58"/>
                    <measurement group_id="O3" value="-1.2" spread="1.47"/>
                    <measurement group_id="O4" value="1.9" spread="1.96"/>
                    <measurement group_id="O5" value="1.8" spread="1.30"/>
                    <measurement group_id="O6" value="1.5" spread="2.07"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="2.83"/>
                    <measurement group_id="O2" value="1.5" spread="3.27"/>
                    <measurement group_id="O3" value="-0.2" spread="2.40"/>
                    <measurement group_id="O4" value="1.1" spread="2.80"/>
                    <measurement group_id="O5" value="1.2" spread="2.11"/>
                    <measurement group_id="O6" value="0.7" spread="3.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="3.06"/>
                    <measurement group_id="O2" value="-1.0" spread="3.03"/>
                    <measurement group_id="O3" value="0.7" spread="1.21"/>
                    <measurement group_id="O4" value="0.3" spread="2.24"/>
                    <measurement group_id="O5" value="2.3" spread="1.87"/>
                    <measurement group_id="O6" value="0.2" spread="2.71"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.1" spread="2.39"/>
                    <measurement group_id="O2" value="0.7" spread="3.20"/>
                    <measurement group_id="O3" value="-1.5" spread="1.05"/>
                    <measurement group_id="O4" value="0.0" spread="2.55"/>
                    <measurement group_id="O5" value="1.3" spread="2.18"/>
                    <measurement group_id="O6" value="0.0" spread="1.41"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="3.45"/>
                    <measurement group_id="O2" value="0.7" spread="3.67"/>
                    <measurement group_id="O3" value="-0.2" spread="1.33"/>
                    <measurement group_id="O4" value="-0.6" spread="1.67"/>
                    <measurement group_id="O5" value="0.4" spread="1.81"/>
                    <measurement group_id="O6" value="-1.8" spread="2.71"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="2.15"/>
                    <measurement group_id="O2" value="0.7" spread="4.08"/>
                    <measurement group_id="O3" value="0.2" spread="2.23"/>
                    <measurement group_id="O4" value="1.1" spread="2.76"/>
                    <measurement group_id="O5" value="0.9" spread="2.98"/>
                    <measurement group_id="O6" value="-0.2" spread="3.06"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="3.18"/>
                    <measurement group_id="O2" value="1.5" spread="2.59"/>
                    <measurement group_id="O3" value="1.5" spread="1.22"/>
                    <measurement group_id="O4" value="0.4" spread="1.88"/>
                    <measurement group_id="O5" value="1.2" spread="2.17"/>
                    <measurement group_id="O6" value="-0.5" spread="3.89"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="2.71"/>
                    <measurement group_id="O2" value="0.5" spread="2.81"/>
                    <measurement group_id="O3" value="0.3" spread="2.42"/>
                    <measurement group_id="O4" value="0.1" spread="3.41"/>
                    <measurement group_id="O5" value="2.3" spread="2.18"/>
                    <measurement group_id="O6" value="0.7" spread="2.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="3.49"/>
                    <measurement group_id="O2" value="0.7" spread="4.63"/>
                    <measurement group_id="O3" value="0.7" spread="2.16"/>
                    <measurement group_id="O4" value="1.2" spread="2.86"/>
                    <measurement group_id="O5" value="0.9" spread="1.69"/>
                    <measurement group_id="O6" value="-0.3" spread="2.88"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="3.66"/>
                    <measurement group_id="O2" value="-0.2" spread="3.06"/>
                    <measurement group_id="O3" value="-0.7" spread="1.97"/>
                    <measurement group_id="O4" value="1.4" spread="2.07"/>
                    <measurement group_id="O5" value="1.4" spread="1.42"/>
                    <measurement group_id="O6" value="1.2" spread="3.25"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="2.59"/>
                    <measurement group_id="O2" value="-0.7" spread="4.41"/>
                    <measurement group_id="O3" value="-0.7" spread="1.51"/>
                    <measurement group_id="O4" value="1.4" spread="2.13"/>
                    <measurement group_id="O5" value="0.7" spread="2.40"/>
                    <measurement group_id="O6" value="0.8" spread="1.94"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.1" spread="2.43"/>
                    <measurement group_id="O2" value="0.5" spread="3.02"/>
                    <measurement group_id="O3" value="-0.7" spread="1.51"/>
                    <measurement group_id="O4" value="0.6" spread="2.01"/>
                    <measurement group_id="O5" value="1.6" spread="2.19"/>
                    <measurement group_id="O6" value="0.3" spread="3.01"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="1.76"/>
                    <measurement group_id="O2" value="1.3" spread="3.01"/>
                    <measurement group_id="O3" value="0.7" spread="2.34"/>
                    <measurement group_id="O6" value="1.0" spread="3.10"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2" spread="1.83"/>
                    <measurement group_id="O4" value="0.2" spread="2.64"/>
                    <measurement group_id="O5" value="1.3" spread="1.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="1.41"/>
                    <measurement group_id="O6" value="-0.3" spread="1.86"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Heart Rate: Electrocardiogram (ECG)</title>
        <description>12-lead ECG were performed in a supine position using an automated ECG machine that calculated the heart rate and measured PR, QRS, QT and corrected QT (QTc) intervals. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at 2 and 8 hours on Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Heart Rate: Electrocardiogram (ECG)</title>
          <description>12-lead ECG were performed in a supine position using an automated ECG machine that calculated the heart rate and measured PR, QRS, QT and corrected QT (QTc) intervals. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Beats per minute</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>2 hours Day1,n=12,6,5,9,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" spread="11.13"/>
                    <measurement group_id="O2" value="-4.3" spread="7.81"/>
                    <measurement group_id="O3" value="-4.6" spread="4.56"/>
                    <measurement group_id="O4" value="0.2" spread="11.06"/>
                    <measurement group_id="O5" value="0.3" spread="11.85"/>
                    <measurement group_id="O6" value="6.8" spread="7.01"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="6.34"/>
                    <measurement group_id="O2" value="-0.8" spread="8.93"/>
                    <measurement group_id="O3" value="-6.3" spread="6.10"/>
                    <measurement group_id="O4" value="-1.3" spread="6.23"/>
                    <measurement group_id="O5" value="0.0" spread="14.05"/>
                    <measurement group_id="O6" value="4.1" spread="6.20"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.4" spread="4.68"/>
                    <measurement group_id="O2" value="-0.4" spread="5.67"/>
                    <measurement group_id="O3" value="0.8" spread="5.29"/>
                    <measurement group_id="O4" value="-1.4" spread="6.32"/>
                    <measurement group_id="O5" value="-0.3" spread="7.34"/>
                    <measurement group_id="O6" value="0.3" spread="1.06"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.5" spread="5.93"/>
                    <measurement group_id="O2" value="0.3" spread="4.15"/>
                    <measurement group_id="O3" value="0.4" spread="7.36"/>
                    <measurement group_id="O4" value="1.5" spread="7.03"/>
                    <measurement group_id="O5" value="3.1" spread="3.48"/>
                    <measurement group_id="O6" value="1.9" spread="3.69"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.5" spread="5.11"/>
                    <measurement group_id="O2" value="1.5" spread="8.64"/>
                    <measurement group_id="O3" value="5.5" spread="9.13"/>
                    <measurement group_id="O4" value="3.1" spread="11.04"/>
                    <measurement group_id="O5" value="2.6" spread="4.60"/>
                    <measurement group_id="O6" value="3.2" spread="3.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.8" spread="4.78"/>
                    <measurement group_id="O2" value="1.5" spread="9.63"/>
                    <measurement group_id="O3" value="0.8" spread="5.24"/>
                    <measurement group_id="O4" value="2.5" spread="5.29"/>
                    <measurement group_id="O5" value="-0.4" spread="5.97"/>
                    <measurement group_id="O6" value="2.6" spread="4.75"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="5.74"/>
                    <measurement group_id="O2" value="1.6" spread="5.76"/>
                    <measurement group_id="O3" value="-2.4" spread="5.53"/>
                    <measurement group_id="O4" value="2.4" spread="9.66"/>
                    <measurement group_id="O5" value="2.0" spread="4.76"/>
                    <measurement group_id="O6" value="4.9" spread="7.60"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.2" spread="5.32"/>
                    <measurement group_id="O2" value="-2.3" spread="5.02"/>
                    <measurement group_id="O3" value="-5.9" spread="5.91"/>
                    <measurement group_id="O4" value="1.8" spread="10.26"/>
                    <measurement group_id="O5" value="1.7" spread="13.56"/>
                    <measurement group_id="O6" value="1.7" spread="7.11"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.8" spread="7.01"/>
                    <measurement group_id="O2" value="-1.6" spread="3.75"/>
                    <measurement group_id="O3" value="-1.2" spread="3.45"/>
                    <measurement group_id="O4" value="-1.6" spread="7.53"/>
                    <measurement group_id="O5" value="-0.3" spread="14.55"/>
                    <measurement group_id="O6" value="-0.9" spread="6.25"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.8" spread="5.91"/>
                    <measurement group_id="O2" value="-0.6" spread="6.22"/>
                    <measurement group_id="O3" value="-2.0" spread="6.02"/>
                    <measurement group_id="O4" value="-2.9" spread="7.50"/>
                    <measurement group_id="O5" value="-0.7" spread="9.14"/>
                    <measurement group_id="O6" value="0.6" spread="4.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="11.83"/>
                    <measurement group_id="O2" value="-1.3" spread="6.24"/>
                    <measurement group_id="O3" value="-3.3" spread="6.35"/>
                    <measurement group_id="O4" value="1.8" spread="15.28"/>
                    <measurement group_id="O5" value="0.4" spread="11.55"/>
                    <measurement group_id="O6" value="1.3" spread="6.44"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.4" spread="9.05"/>
                    <measurement group_id="O2" value="-0.4" spread="6.59"/>
                    <measurement group_id="O3" value="-3.3" spread="5.20"/>
                    <measurement group_id="O4" value="1.6" spread="6.92"/>
                    <measurement group_id="O5" value="0.6" spread="8.78"/>
                    <measurement group_id="O6" value="2.2" spread="4.65"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="7.95"/>
                    <measurement group_id="O2" value="-0.2" spread="8.28"/>
                    <measurement group_id="O3" value="2.5" spread="8.00"/>
                    <measurement group_id="O4" value="-0.3" spread="9.13"/>
                    <measurement group_id="O5" value="1.7" spread="11.03"/>
                    <measurement group_id="O6" value="1.2" spread="6.47"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="9.35"/>
                    <measurement group_id="O2" value="-0.3" spread="5.16"/>
                    <measurement group_id="O3" value="-1.5" spread="7.18"/>
                    <measurement group_id="O4" value="2.5" spread="11.97"/>
                    <measurement group_id="O5" value="2.0" spread="8.22"/>
                    <measurement group_id="O6" value="0.3" spread="7.66"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="9.21"/>
                    <measurement group_id="O2" value="-4.6" spread="7.34"/>
                    <measurement group_id="O3" value="0.7" spread="5.84"/>
                    <measurement group_id="O6" value="2.3" spread="6.46"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.5" spread="7.13"/>
                    <measurement group_id="O4" value="-0.2" spread="10.26"/>
                    <measurement group_id="O5" value="1.3" spread="5.74"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.3" spread="0.47"/>
                    <measurement group_id="O6" value="3.6" spread="9.08"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in PR Interval, QRS Interval, QT Interval and QT Interval Corrected by Fridericia's Formula (QTcF) Interval</title>
        <description>12-lead ECG were performed in a supine position using an automated ECG machine that calculated PR interval, QRS interval, QT interval and QTcF interval. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at 2 and 8 hours on Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in PR Interval, QRS Interval, QT Interval and QT Interval Corrected by Fridericia's Formula (QTcF) Interval</title>
          <description>12-lead ECG were performed in a supine position using an automated ECG machine that calculated PR interval, QRS interval, QT interval and QTcF interval. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Milliseconds</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>PR Interval,2 hours Day1,n=12,6,5,9,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.5" spread="9.46"/>
                    <measurement group_id="O2" value="3.9" spread="2.85"/>
                    <measurement group_id="O3" value="3.5" spread="8.47"/>
                    <measurement group_id="O4" value="-4.3" spread="9.10"/>
                    <measurement group_id="O5" value="3.7" spread="1.075"/>
                    <measurement group_id="O6" value="-7.5" spread="12.23"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.1" spread="8.49"/>
                    <measurement group_id="O2" value="3.1" spread="6.02"/>
                    <measurement group_id="O3" value="-1.8" spread="3.72"/>
                    <measurement group_id="O4" value="-4.5" spread="11.76"/>
                    <measurement group_id="O5" value="1.9" spread="11.39"/>
                    <measurement group_id="O6" value="-3.3" spread="10.88"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="11.51"/>
                    <measurement group_id="O2" value="2.0" spread="4.11"/>
                    <measurement group_id="O3" value="1.4" spread="3.95"/>
                    <measurement group_id="O4" value="-4.4" spread="9.86"/>
                    <measurement group_id="O5" value="6.2" spread="11.05"/>
                    <measurement group_id="O6" value="-4.1" spread="11.25"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3" spread="6.68"/>
                    <measurement group_id="O2" value="5.2" spread="4.29"/>
                    <measurement group_id="O3" value="0.5" spread="5.62"/>
                    <measurement group_id="O4" value="-3.6" spread="11.96"/>
                    <measurement group_id="O5" value="6.0" spread="7.60"/>
                    <measurement group_id="O6" value="-1.4" spread="8.82"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="6.80"/>
                    <measurement group_id="O2" value="8.1" spread="5.21"/>
                    <measurement group_id="O3" value="-2.5" spread="6.12"/>
                    <measurement group_id="O4" value="-2.3" spread="8.88"/>
                    <measurement group_id="O5" value="8.6" spread="10.17"/>
                    <measurement group_id="O6" value="-4.3" spread="7.54"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.3" spread="6.22"/>
                    <measurement group_id="O2" value="8.3" spread="8.22"/>
                    <measurement group_id="O3" value="3.5" spread="10.05"/>
                    <measurement group_id="O4" value="-0.2" spread="4.54"/>
                    <measurement group_id="O5" value="10.0" spread="8.44"/>
                    <measurement group_id="O6" value="-1.2" spread="4.91"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="8.12"/>
                    <measurement group_id="O2" value="0.8" spread="5.58"/>
                    <measurement group_id="O3" value="2.2" spread="5.69"/>
                    <measurement group_id="O4" value="-3.2" spread="12.26"/>
                    <measurement group_id="O5" value="7.0" spread="6.62"/>
                    <measurement group_id="O6" value="4.5" spread="6.73"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="8.62"/>
                    <measurement group_id="O2" value="5.3" spread="6.60"/>
                    <measurement group_id="O3" value="5.5" spread="10.34"/>
                    <measurement group_id="O4" value="1.8" spread="12.19"/>
                    <measurement group_id="O5" value="2.0" spread="12.64"/>
                    <measurement group_id="O6" value="1.0" spread="2.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 4,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.7" spread="10.27"/>
                    <measurement group_id="O2" value="5.2" spread="3.37"/>
                    <measurement group_id="O3" value="1.8" spread="12.71"/>
                    <measurement group_id="O4" value="-1.8" spread="15.25"/>
                    <measurement group_id="O5" value="3.9" spread="11.28"/>
                    <measurement group_id="O6" value="-4.0" spread="17.49"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.1" spread="8.27"/>
                    <measurement group_id="O2" value="3.2" spread="9.65"/>
                    <measurement group_id="O3" value="-2.6" spread="10.27"/>
                    <measurement group_id="O4" value="-3.6" spread="10.33"/>
                    <measurement group_id="O5" value="3.4" spread="8.10"/>
                    <measurement group_id="O6" value="-1.9" spread="9.55"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.4" spread="7.87"/>
                    <measurement group_id="O2" value="3.9" spread="10.53"/>
                    <measurement group_id="O3" value="-4.4" spread="12.18"/>
                    <measurement group_id="O4" value="-3.8" spread="13.26"/>
                    <measurement group_id="O5" value="9.4" spread="8.33"/>
                    <measurement group_id="O6" value="-2.1" spread="10.04"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.5" spread="10.74"/>
                    <measurement group_id="O2" value="1.5" spread="3.99"/>
                    <measurement group_id="O3" value="0.1" spread="7.74"/>
                    <measurement group_id="O4" value="-5.6" spread="11.87"/>
                    <measurement group_id="O5" value="7.3" spread="13.34"/>
                    <measurement group_id="O6" value="-2.0" spread="9.72"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3" spread="7.98"/>
                    <measurement group_id="O2" value="1.4" spread="3.91"/>
                    <measurement group_id="O3" value="3.7" spread="7.25"/>
                    <measurement group_id="O4" value="-7.4" spread="11.56"/>
                    <measurement group_id="O5" value="5.5" spread="12.45"/>
                    <measurement group_id="O6" value="-5.6" spread="7.87"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="6.20"/>
                    <measurement group_id="O2" value="3.0" spread="4.67"/>
                    <measurement group_id="O3" value="3.7" spread="11.62"/>
                    <measurement group_id="O4" value="-3.2" spread="13.01"/>
                    <measurement group_id="O5" value="6.9" spread="11.36"/>
                    <measurement group_id="O6" value="-4.8" spread="11.69"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.3" spread="8.16"/>
                    <measurement group_id="O2" value="5.4" spread="7.23"/>
                    <measurement group_id="O3" value="0.0" spread="7.99"/>
                    <measurement group_id="O6" value="-3.3" spread="11.91"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="8.26"/>
                    <measurement group_id="O4" value="-3.7" spread="8.49"/>
                    <measurement group_id="O5" value="2.9" spread="12.08"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Interval,Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-13.7" spread="6.60"/>
                    <measurement group_id="O6" value="-3.6" spread="8.56"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,2 hours Day1,n=12,6,5,9,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="4.87"/>
                    <measurement group_id="O2" value="0.2" spread="4.63"/>
                    <measurement group_id="O3" value="-7.2" spread="4.97"/>
                    <measurement group_id="O4" value="0.0" spread="4.43"/>
                    <measurement group_id="O5" value="-1.5" spread="6.14"/>
                    <measurement group_id="O6" value="-1.2" spread="3.62"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="6.83"/>
                    <measurement group_id="O2" value="-0.2" spread="6.81"/>
                    <measurement group_id="O3" value="-4.0" spread="6.18"/>
                    <measurement group_id="O4" value="-1.1" spread="3.18"/>
                    <measurement group_id="O5" value="-2.8" spread="5.03"/>
                    <measurement group_id="O6" value="-3.1" spread="4.42"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.8" spread="4.64"/>
                    <measurement group_id="O2" value="0.5" spread="4.63"/>
                    <measurement group_id="O3" value="-4.9" spread="4.60"/>
                    <measurement group_id="O4" value="-2.7" spread="5.28"/>
                    <measurement group_id="O5" value="-3.0" spread="6.27"/>
                    <measurement group_id="O6" value="-3.7" spread="4.62"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" spread="3.44"/>
                    <measurement group_id="O2" value="1.4" spread="4.18"/>
                    <measurement group_id="O3" value="-1.3" spread="3.14"/>
                    <measurement group_id="O4" value="-0.6" spread="4.03"/>
                    <measurement group_id="O5" value="-2.6" spread="5.15"/>
                    <measurement group_id="O6" value="-2.6" spread="1.54"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.4" spread="3.78"/>
                    <measurement group_id="O2" value="1.9" spread="3.72"/>
                    <measurement group_id="O3" value="-7.8" spread="5.52"/>
                    <measurement group_id="O4" value="1.1" spread="5.28"/>
                    <measurement group_id="O5" value="-0.7" spread="5.24"/>
                    <measurement group_id="O6" value="-2.2" spread="3.38"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="4.05"/>
                    <measurement group_id="O2" value="0.2" spread="5.85"/>
                    <measurement group_id="O3" value="-7.3" spread="4.79"/>
                    <measurement group_id="O4" value="-0.2" spread="5.40"/>
                    <measurement group_id="O5" value="0.7" spread="5.09"/>
                    <measurement group_id="O6" value="-2.9" spread="2.35"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3" spread="5.05"/>
                    <measurement group_id="O2" value="0.6" spread="5.85"/>
                    <measurement group_id="O3" value="-3.7" spread="6.18"/>
                    <measurement group_id="O4" value="0.6" spread="4.90"/>
                    <measurement group_id="O5" value="-2.4" spread="5.61"/>
                    <measurement group_id="O6" value="-2.8" spread="4.20"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.1" spread="3.76"/>
                    <measurement group_id="O2" value="2.1" spread="4.82"/>
                    <measurement group_id="O3" value="-3.9" spread="4.76"/>
                    <measurement group_id="O4" value="0.9" spread="2.86"/>
                    <measurement group_id="O5" value="-3.0" spread="5.47"/>
                    <measurement group_id="O6" value="-1.4" spread="3.11"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 4,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.0" spread="6.49"/>
                    <measurement group_id="O2" value="1.8" spread="7.34"/>
                    <measurement group_id="O3" value="-6.5" spread="7.76"/>
                    <measurement group_id="O4" value="1.9" spread="4.79"/>
                    <measurement group_id="O5" value="-2.6" spread="4.98"/>
                    <measurement group_id="O6" value="-3.3" spread="3.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.9" spread="7.27"/>
                    <measurement group_id="O2" value="-1.0" spread="4.35"/>
                    <measurement group_id="O3" value="-3.6" spread="5.23"/>
                    <measurement group_id="O4" value="0.9" spread="4.12"/>
                    <measurement group_id="O5" value="0.5" spread="5.71"/>
                    <measurement group_id="O6" value="-1.9" spread="1.83"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.6" spread="4.20"/>
                    <measurement group_id="O2" value="3.1" spread="3.28"/>
                    <measurement group_id="O3" value="-4.4" spread="6.04"/>
                    <measurement group_id="O4" value="-0.1" spread="5.23"/>
                    <measurement group_id="O5" value="-2.5" spread="3.11"/>
                    <measurement group_id="O6" value="-1.1" spread="3.21"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.6" spread="3.90"/>
                    <measurement group_id="O2" value="1.8" spread="2.79"/>
                    <measurement group_id="O3" value="-5.0" spread="5.43"/>
                    <measurement group_id="O4" value="0.4" spread="3.16"/>
                    <measurement group_id="O5" value="-2.9" spread="4.53"/>
                    <measurement group_id="O6" value="-1.6" spread="4.17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.6" spread="5.94"/>
                    <measurement group_id="O2" value="1.8" spread="6.53"/>
                    <measurement group_id="O3" value="-6.5" spread="5.56"/>
                    <measurement group_id="O4" value="-1.1" spread="3.76"/>
                    <measurement group_id="O5" value="-3.1" spread="2.01"/>
                    <measurement group_id="O6" value="-1.8" spread="5.12"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="4.61"/>
                    <measurement group_id="O2" value="2.1" spread="4.64"/>
                    <measurement group_id="O3" value="-5.5" spread="5.75"/>
                    <measurement group_id="O4" value="0.4" spread="5.55"/>
                    <measurement group_id="O5" value="-2.7" spread="6.57"/>
                    <measurement group_id="O6" value="0.4" spread="3.40"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.9" spread="5.78"/>
                    <measurement group_id="O2" value="2.0" spread="5.17"/>
                    <measurement group_id="O3" value="-6.1" spread="4.50"/>
                    <measurement group_id="O6" value="-1.3" spread="2.56"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.7" spread="6.19"/>
                    <measurement group_id="O4" value="0.7" spread="5.14"/>
                    <measurement group_id="O5" value="-3.9" spread="4.84"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Interval,Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="0.47"/>
                    <measurement group_id="O6" value="-3.0" spread="3.47"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,2 hours Day1,n=12,6,5,9,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.6" spread="22.55"/>
                    <measurement group_id="O2" value="14.8" spread="16.65"/>
                    <measurement group_id="O3" value="6.0" spread="11.28"/>
                    <measurement group_id="O4" value="-2.9" spread="20.19"/>
                    <measurement group_id="O5" value="-3.7" spread="23.95"/>
                    <measurement group_id="O6" value="-9.2" spread="18.68"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-7.5" spread="16.46"/>
                    <measurement group_id="O2" value="6.7" spread="16.22"/>
                    <measurement group_id="O3" value="12.6" spread="18.53"/>
                    <measurement group_id="O4" value="1.5" spread="14.29"/>
                    <measurement group_id="O5" value="-0.7" spread="29.93"/>
                    <measurement group_id="O6" value="-7.6" spread="22.43"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.9" spread="19.32"/>
                    <measurement group_id="O2" value="4.3" spread="14.01"/>
                    <measurement group_id="O3" value="-14.1" spread="16.26"/>
                    <measurement group_id="O4" value="-3.0" spread="18.80"/>
                    <measurement group_id="O5" value="-6.1" spread="15.86"/>
                    <measurement group_id="O6" value="-0.6" spread="11.09"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-10.1" spread="19.82"/>
                    <measurement group_id="O2" value="-0.9" spread="10.33"/>
                    <measurement group_id="O3" value="-6.9" spread="14.95"/>
                    <measurement group_id="O4" value="-7.6" spread="18.49"/>
                    <measurement group_id="O5" value="-13.2" spread="15.20"/>
                    <measurement group_id="O6" value="-2.4" spread="9.29"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-12.3" spread="17.15"/>
                    <measurement group_id="O2" value="-2.2" spread="14.32"/>
                    <measurement group_id="O3" value="-15.9" spread="21.55"/>
                    <measurement group_id="O4" value="-11.6" spread="25.81"/>
                    <measurement group_id="O5" value="-10.9" spread="11.99"/>
                    <measurement group_id="O6" value="-3.2" spread="17.05"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.9" spread="14.18"/>
                    <measurement group_id="O2" value="-2.2" spread="21.88"/>
                    <measurement group_id="O3" value="-14.3" spread="13.83"/>
                    <measurement group_id="O4" value="-9.5" spread="14.97"/>
                    <measurement group_id="O5" value="-4.1" spread="18.72"/>
                    <measurement group_id="O6" value="-1.3" spread="11.57"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.3" spread="17.30"/>
                    <measurement group_id="O2" value="8.7" spread="14.19"/>
                    <measurement group_id="O3" value="0.0" spread="21.14"/>
                    <measurement group_id="O4" value="-9.4" spread="19.82"/>
                    <measurement group_id="O5" value="-1.0" spread="22.22"/>
                    <measurement group_id="O6" value="-5.6" spread="23.13"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="9.4" spread="16.23"/>
                    <measurement group_id="O2" value="12.9" spread="8.14"/>
                    <measurement group_id="O3" value="7.8" spread="17.65"/>
                    <measurement group_id="O4" value="1.0" spread="22.66"/>
                    <measurement group_id="O5" value="-6.1" spread="17.10"/>
                    <measurement group_id="O6" value="8.3" spread="20.06"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 4,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="9.4" spread="20.43"/>
                    <measurement group_id="O2" value="11.0" spread="4.78"/>
                    <measurement group_id="O3" value="-3.6" spread="24.50"/>
                    <measurement group_id="O4" value="3.3" spread="17.80"/>
                    <measurement group_id="O5" value="1.7" spread="34.52"/>
                    <measurement group_id="O6" value="14.0" spread="18.29"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="20.74"/>
                    <measurement group_id="O2" value="6.9" spread="9.28"/>
                    <measurement group_id="O3" value="1.0" spread="23.62"/>
                    <measurement group_id="O4" value="4.6" spread="19.06"/>
                    <measurement group_id="O5" value="-2.0" spread="20.79"/>
                    <measurement group_id="O6" value="6.0" spread="15.76"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.8" spread="20.64"/>
                    <measurement group_id="O2" value="8.1" spread="16.21"/>
                    <measurement group_id="O3" value="4.2" spread="22.53"/>
                    <measurement group_id="O4" value="-6.5" spread="28.72"/>
                    <measurement group_id="O5" value="-2.1" spread="26.69"/>
                    <measurement group_id="O6" value="1.1" spread="14.24"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.3" spread="22.44"/>
                    <measurement group_id="O2" value="6.3" spread="15.00"/>
                    <measurement group_id="O3" value="-2.8" spread="15.12"/>
                    <measurement group_id="O4" value="-4.5" spread="19.10"/>
                    <measurement group_id="O5" value="-6.7" spread="23.77"/>
                    <measurement group_id="O6" value="0.5" spread="12.14"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.1" spread="23.22"/>
                    <measurement group_id="O2" value="4.2" spread="18.11"/>
                    <measurement group_id="O3" value="-9.9" spread="27.45"/>
                    <measurement group_id="O4" value="0.7" spread="19.24"/>
                    <measurement group_id="O5" value="-8.6" spread="19.00"/>
                    <measurement group_id="O6" value="7.9" spread="23.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3" spread="27.36"/>
                    <measurement group_id="O2" value="10.2" spread="12.92"/>
                    <measurement group_id="O3" value="0.9" spread="29.72"/>
                    <measurement group_id="O4" value="-6.1" spread="22.91"/>
                    <measurement group_id="O5" value="-9.8" spread="18.29"/>
                    <measurement group_id="O6" value="13.2" spread="20.96"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.7" spread="20.32"/>
                    <measurement group_id="O2" value="12.9" spread="12.12"/>
                    <measurement group_id="O3" value="-14.4" spread="17.64"/>
                    <measurement group_id="O6" value="5.3" spread="14.64"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.4" spread="41.25"/>
                    <measurement group_id="O4" value="-3.4" spread="29.83"/>
                    <measurement group_id="O5" value="-9.3" spread="16.00"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Interval,Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="23.5" spread="17.68"/>
                    <measurement group_id="O6" value="-0.9" spread="24.13"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,2 hours Day1,n=12,6,5,9,8,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="9.11"/>
                    <measurement group_id="O2" value="4.1" spread="8.67"/>
                    <measurement group_id="O3" value="-5.5" spread="8.11"/>
                    <measurement group_id="O4" value="-3.4" spread="6.40"/>
                    <measurement group_id="O5" value="-2.3" spread="5.38"/>
                    <measurement group_id="O6" value="6.4" spread="5.17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,8 hours Day1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.8" spread="12.97"/>
                    <measurement group_id="O2" value="4.3" spread="7.93"/>
                    <measurement group_id="O3" value="-3.6" spread="12.32"/>
                    <measurement group_id="O4" value="-1.4" spread="9.87"/>
                    <measurement group_id="O5" value="-0.4" spread="8.32"/>
                    <measurement group_id="O6" value="2.1" spread="13.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.0" spread="11.78"/>
                    <measurement group_id="O2" value="2.6" spread="8.43"/>
                    <measurement group_id="O3" value="-12.8" spread="10.87"/>
                    <measurement group_id="O4" value="-6.9" spread="9.34"/>
                    <measurement group_id="O5" value="-5.9" spread="5.70"/>
                    <measurement group_id="O6" value="-0.2" spread="10.66"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.8" spread="14.99"/>
                    <measurement group_id="O2" value="0.4" spread="5.82"/>
                    <measurement group_id="O3" value="-6.5" spread="9.14"/>
                    <measurement group_id="O4" value="-5.3" spread="9.95"/>
                    <measurement group_id="O5" value="-6.3" spread="10.71"/>
                    <measurement group_id="O6" value="1.9" spread="14.28"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.9" spread="14.08"/>
                    <measurement group_id="O2" value="0.7" spread="7.62"/>
                    <measurement group_id="O3" value="-6.1" spread="7.10"/>
                    <measurement group_id="O4" value="-7.7" spread="12.56"/>
                    <measurement group_id="O5" value="-4.8" spread="10.75"/>
                    <measurement group_id="O6" value="3.5" spread="17.05"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="11.97"/>
                    <measurement group_id="O2" value="1.5" spread="14.24"/>
                    <measurement group_id="O3" value="-13.6" spread="11.17"/>
                    <measurement group_id="O4" value="-4.7" spread="9.86"/>
                    <measurement group_id="O5" value="-4.4" spread="14.31"/>
                    <measurement group_id="O6" value="3.9" spread="16.06"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 1,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="10.95"/>
                    <measurement group_id="O2" value="10.3" spread="7.33"/>
                    <measurement group_id="O3" value="-6.7" spread="12.72"/>
                    <measurement group_id="O4" value="-5.4" spread="8.38"/>
                    <measurement group_id="O5" value="2.8" spread="12.12"/>
                    <measurement group_id="O6" value="5.5" spread="13.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.9" spread="16.40"/>
                    <measurement group_id="O2" value="6.3" spread="6.98"/>
                    <measurement group_id="O3" value="-8.3" spread="8.21"/>
                    <measurement group_id="O4" value="3.7" spread="19.35"/>
                    <measurement group_id="O5" value="-2.3" spread="12.64"/>
                    <measurement group_id="O6" value="11.5" spread="12.63"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 4,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="11.22"/>
                    <measurement group_id="O2" value="7.3" spread="7.10"/>
                    <measurement group_id="O3" value="-6.6" spread="20.63"/>
                    <measurement group_id="O4" value="0.5" spread="10.86"/>
                    <measurement group_id="O5" value="-0.7" spread="10.97"/>
                    <measurement group_id="O6" value="11.4" spread="6.33"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="13.76"/>
                    <measurement group_id="O2" value="5.2" spread="9.28"/>
                    <measurement group_id="O3" value="-4.8" spread="14.70"/>
                    <measurement group_id="O4" value="-1.7" spread="11.96"/>
                    <measurement group_id="O5" value="-2.9" spread="14.10"/>
                    <measurement group_id="O6" value="8.1" spread="20.96"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.4" spread="14.39"/>
                    <measurement group_id="O2" value="5.9" spread="13.50"/>
                    <measurement group_id="O3" value="-5.3" spread="10.66"/>
                    <measurement group_id="O4" value="-5.9" spread="10.93"/>
                    <measurement group_id="O5" value="-1.1" spread="11.91"/>
                    <measurement group_id="O6" value="4.7" spread="10.23"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="11.73"/>
                    <measurement group_id="O2" value="4.8" spread="6.79"/>
                    <measurement group_id="O3" value="-10.4" spread="9.42"/>
                    <measurement group_id="O4" value="-0.6" spread="12.29"/>
                    <measurement group_id="O5" value="-5.2" spread="12.81"/>
                    <measurement group_id="O6" value="5.9" spread="11.16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" spread="15.42"/>
                    <measurement group_id="O2" value="3.0" spread="10.83"/>
                    <measurement group_id="O3" value="-7.2" spread="12.14"/>
                    <measurement group_id="O4" value="0.4" spread="7.96"/>
                    <measurement group_id="O5" value="-3.9" spread="12.69"/>
                    <measurement group_id="O6" value="10.1" spread="15.15"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.9" spread="16.58"/>
                    <measurement group_id="O2" value="9.6" spread="9.37"/>
                    <measurement group_id="O3" value="-3.9" spread="14.54"/>
                    <measurement group_id="O4" value="-1.7" spread="10.65"/>
                    <measurement group_id="O5" value="-4.4" spread="12.21"/>
                    <measurement group_id="O6" value="12.8" spread="8.59"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.4" spread="10.98"/>
                    <measurement group_id="O2" value="1.3" spread="7.93"/>
                    <measurement group_id="O3" value="-13.8" spread="8.76"/>
                    <measurement group_id="O6" value="11.7" spread="13.74"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.7" spread="24.89"/>
                    <measurement group_id="O4" value="-4.3" spread="13.45"/>
                    <measurement group_id="O5" value="-5.5" spread="14.23"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Interval,Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="12.0" spread="17.44"/>
                    <measurement group_id="O6" value="7.5" spread="14.62"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Area Under the Curve From Time Zero to Infinity (AUC[0-inf]) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis. Pharmacokinetic Population included participants in the Safety population for whom a pharmcokinetic sample was obtained and analyzed.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population.</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Area Under the Curve From Time Zero to Infinity (AUC[0-inf]) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis. Pharmacokinetic Population included participants in the Safety population for whom a pharmcokinetic sample was obtained and analyzed.</description>
          <population>Pharmacokinetic Population.</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="24.795" spread="51.6"/>
                    <measurement group_id="O2" value="68.904" spread="23.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>AUC(0-inf) of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population.</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>AUC(0-inf) of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population.</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="208.308" spread="39.6"/>
                    <measurement group_id="O2" value="846.686" spread="7.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>AUC(0-inf) of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population.</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>AUC(0-inf) of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population.</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1873.657" spread="25.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Area Under the Curve From Time Zero to the Last Measurable Concentration (AUC[0-t]) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population.</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Area Under the Curve From Time Zero to the Last Measurable Concentration (AUC[0-t]) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population.</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="18.369" spread="59.2"/>
                    <measurement group_id="O2" value="62.101" spread="28.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>AUC(0-t) of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>AUC(0-t) of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="201.434" spread="41.1"/>
                    <measurement group_id="O2" value="830.245" spread="7.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>AUC(0-t) of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>AUC(0-t) of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1855.619" spread="25.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Area Under the Concentration-time Curve From Time Zero to Week 4 (AUC[0-Week 4]) of GSK3511294</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 4). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, and 4 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Area Under the Concentration-time Curve From Time Zero to Week 4 (AUC[0-Week 4]) of GSK3511294</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 4). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="9"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.856" spread="22.0"/>
                    <measurement group_id="O2" value="19.685" spread="14.0"/>
                    <measurement group_id="O3" value="62.994" spread="40.6"/>
                    <measurement group_id="O4" value="292.698" spread="11.0"/>
                    <measurement group_id="O5" value="676.055" spread="22.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Area Under the Concentration-time Curve From Time Zero to Week 12 (AUC[0-Week 12]) of GSK3511294</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 12). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8 and 12 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Area Under the Concentration-time Curve From Time Zero to Week 12 (AUC[0-Week 12]) of GSK3511294</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 12). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="9"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="16.102" spread="37.1"/>
                    <measurement group_id="O2" value="48.389" spread="22.7"/>
                    <measurement group_id="O3" value="148.798" spread="37.8"/>
                    <measurement group_id="O4" value="663.984" spread="8.1"/>
                    <measurement group_id="O5" value="1445.726" spread="23.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Area Under the Concentration-time Curve From Time Zero to Week 26 (AUC [0-Week 26]) of GSK3511294</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 26). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24 and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Area Under the Concentration-time Curve From Time Zero to Week 26 (AUC [0-Week 26]) of GSK3511294</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 26). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day*microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="9"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="21.829" spread="42.7"/>
                    <measurement group_id="O2" value="64.453" spread="24.3"/>
                    <measurement group_id="O3" value="199.893" spread="39.9"/>
                    <measurement group_id="O4" value="805.359" spread="7.7"/>
                    <measurement group_id="O5" value="1789.451" spread="26.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Percentage of AUC (0-inf) Obtained by Extrapolation (%AUCex) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Percentage of AUC (0-inf) Obtained by Extrapolation (%AUCex) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Percentage of AUCex</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="24.3560" spread="35.8"/>
                    <measurement group_id="O2" value="7.7705" spread="81.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>%AUCex of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>%AUCex of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Percentage of AUCex</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.9636" spread="55.6"/>
                    <measurement group_id="O2" value="1.4162" spread="88.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>%AUCex of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>%AUCex of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Percentage of AUCex</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.9096" spread="35.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Maximum Observed Concentration (Cmax) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Maximum Observed Concentration (Cmax) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3400" spread="25.3"/>
                    <measurement group_id="O2" value="0.8759" spread="18.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Cmax of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Cmax of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.8101" spread="41.1"/>
                    <measurement group_id="O2" value="12.2471" spread="15.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Cmax of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Cmax of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Microgram per milliliter</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="28.5987" spread="23.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time of Occurrence of Cmax (Tmax) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Time of Occurrence of Cmax (Tmax) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10.966" lower_limit="6.99" upper_limit="27.98"/>
                    <measurement group_id="O2" value="7.956" lower_limit="7.00" upper_limit="28.91"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Tmax of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Tmax of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="13.943" lower_limit="4.00" upper_limit="28.02"/>
                    <measurement group_id="O2" value="13.970" lower_limit="3.97" upper_limit="16.00"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Tmax of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Tmax of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="13.909" lower_limit="2.00" upper_limit="15.00"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time of Last Quantifiable Concentration (Tlast) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Time of Last Quantifiable Concentration (Tlast) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="84.47" lower_limit="84.0" upper_limit="182.0"/>
                    <measurement group_id="O2" value="176.46" lower_limit="126.0" upper_limit="185.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Tlast of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population.</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Tlast of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population.</population>
          <units>Days</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="182.01" lower_limit="182.0" upper_limit="254.8"/>
                    <measurement group_id="O2" value="252.00" lower_limit="250.0" upper_limit="255.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Tlast of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Tlast of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="279.99" lower_limit="278.0" upper_limit="283.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Apparent Clearance Following Subcutaneous Dosing (CL/F) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Apparent Clearance Following Subcutaneous Dosing (CL/F) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Liters per day</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.08066" spread="51.6"/>
                    <measurement group_id="O2" value="0.14513" spread="23.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>CL/F of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>CL/F of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Liters per day</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.14402" spread="39.6"/>
                    <measurement group_id="O2" value="0.11811" spread="7.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>CL/F of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>CL/F of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Liters per day</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.16011" spread="25.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Apparent Volume of Distribution After Subcutaneous Administration (Vd/F) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by terminal elimination rate constant (lambda_z) *AUC(0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Apparent Volume of Distribution After Subcutaneous Administration (Vd/F) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by terminal elimination rate constant (lambda_z) *AUC(0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Liters</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.113" spread="37.6"/>
                    <measurement group_id="O2" value="9.193" spread="34.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Vd/F of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Vd/F of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Liters</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.812" spread="40.4"/>
                    <measurement group_id="O2" value="6.630" spread="12.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Vd/F of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Vd/F of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Liters</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="9.337" spread="30.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Terminal Phase Elimination Rate Constant (Lambda_z) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Terminal Phase Elimination Rate Constant (Lambda_z) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day^-1</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.013195" spread="37.3"/>
                    <measurement group_id="O2" value="0.015787" spread="16.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Lambda_z of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Lambda_z of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day^-1</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.018435" spread="10.7"/>
                    <measurement group_id="O2" value="0.017813" spread="11.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Lambda_z of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Lambda_z of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Day^-1</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.017148" spread="6.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Terminal Phase Half-life (t1/2) of GSK3511294 2 mg and 10 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Terminal Phase Half-life (t1/2) of GSK3511294 2 mg and 10 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="52.531" spread="37.3"/>
                    <measurement group_id="O2" value="43.907" spread="16.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>T1/2 of GSK3511294 30 mg and 100 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>T1/2 of GSK3511294 30 mg and 100 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9"/>
                <count group_id="O2" value="9"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="37.599" spread="10.7"/>
                    <measurement group_id="O2" value="38.913" spread="11.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>T1/2 of GSK3511294 300 mg</title>
        <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
        <time_frame>Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose</time_frame>
        <population>Pharmacokinetic Population</population>
        <group_list>
          <group group_id="O1">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>T1/2 of GSK3511294 300 mg</title>
          <description>Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.</description>
          <population>Pharmacokinetic Population</population>
          <units>Days</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="40.422" spread="6.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Ratio to Baseline in Absolute Blood Eosinophil Count</title>
        <description>Blood samples were collected at indicated time-points. Analysis was performed using a mixed model repeated measures analysis (MMRM) model on log-transformed data with fixed categorical effects of treatment, planned timepoint and treatment-by-planned timepoint interaction and fixed continuous covariates of log Baseline blood eosinophil count and log Baseline blood eosinophil count-by-planned timepoint interaction. Baseline is defined as the latest predose non-missing blood eosinophil count. Ratio to Baseline is defined as post-dose visit value divided by Baseline value. Pharmacodynamic Population included participants in the 'Safety' population for whom a post-dose pharmacodynamic (ie blood eosinophil) sample was obtained and analyzed.</description>
        <time_frame>Baseline, Days 2, 3, 4, 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36, and 40</time_frame>
        <population>Pharmacodynamic Population. Only those participants with planned assessments at that particular time point has been presented (represented by n=X in category titles)</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Ratio to Baseline in Absolute Blood Eosinophil Count</title>
          <description>Blood samples were collected at indicated time-points. Analysis was performed using a mixed model repeated measures analysis (MMRM) model on log-transformed data with fixed categorical effects of treatment, planned timepoint and treatment-by-planned timepoint interaction and fixed continuous covariates of log Baseline blood eosinophil count and log Baseline blood eosinophil count-by-planned timepoint interaction. Baseline is defined as the latest predose non-missing blood eosinophil count. Ratio to Baseline is defined as post-dose visit value divided by Baseline value. Pharmacodynamic Population included participants in the 'Safety' population for whom a post-dose pharmacodynamic (ie blood eosinophil) sample was obtained and analyzed.</description>
          <population>Pharmacodynamic Population. Only those participants with planned assessments at that particular time point has been presented (represented by n=X in category titles)</population>
          <units>Ratio of eosinophils in blood</units>
          <param>Least Squares Mean</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2, n=12, 6, 6, 8, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.083" lower_limit="0.828" upper_limit="1.418"/>
                    <measurement group_id="O2" value="0.562" lower_limit="0.382" upper_limit="0.827"/>
                    <measurement group_id="O3" value="0.522" lower_limit="0.356" upper_limit="0.765"/>
                    <measurement group_id="O4" value="0.434" lower_limit="0.313" upper_limit="0.601"/>
                    <measurement group_id="O5" value="0.496" lower_limit="0.364" upper_limit="0.677"/>
                    <measurement group_id="O6" value="0.466" lower_limit="0.317" upper_limit="0.683"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3, n=12, 6, 6, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.977" lower_limit="0.747" upper_limit="1.279"/>
                    <measurement group_id="O2" value="0.431" lower_limit="0.293" upper_limit="0.633"/>
                    <measurement group_id="O3" value="0.350" lower_limit="0.238" upper_limit="0.512"/>
                    <measurement group_id="O4" value="0.281" lower_limit="0.205" upper_limit="0.386"/>
                    <measurement group_id="O5" value="0.262" lower_limit="0.192" upper_limit="0.357"/>
                    <measurement group_id="O6" value="0.403" lower_limit="0.275" upper_limit="0.591"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4, n=12, 6, 6, 8, 8, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="8"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.008" lower_limit="0.770" upper_limit="1.319"/>
                    <measurement group_id="O2" value="0.400" lower_limit="0.272" upper_limit="0.589"/>
                    <measurement group_id="O3" value="0.340" lower_limit="0.232" upper_limit="0.499"/>
                    <measurement group_id="O4" value="0.215" lower_limit="0.155" upper_limit="0.298"/>
                    <measurement group_id="O5" value="0.250" lower_limit="0.182" upper_limit="0.344"/>
                    <measurement group_id="O6" value="0.360" lower_limit="0.246" upper_limit="0.528"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5, n=11, 6, 6, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.927" lower_limit="0.705" upper_limit="1.220"/>
                    <measurement group_id="O2" value="0.300" lower_limit="0.204" upper_limit="0.442"/>
                    <measurement group_id="O3" value="0.267" lower_limit="0.182" upper_limit="0.391"/>
                    <measurement group_id="O4" value="0.219" lower_limit="0.159" upper_limit="0.300"/>
                    <measurement group_id="O5" value="0.280" lower_limit="0.205" upper_limit="0.382"/>
                    <measurement group_id="O6" value="0.299" lower_limit="0.204" upper_limit="0.438"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1, n=12, 6, 6, 9, 9, 5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.136" lower_limit="0.868" upper_limit="1.487"/>
                    <measurement group_id="O2" value="0.304" lower_limit="0.206" upper_limit="0.447"/>
                    <measurement group_id="O3" value="0.223" lower_limit="0.152" upper_limit="0.326"/>
                    <measurement group_id="O4" value="0.226" lower_limit="0.165" upper_limit="0.311"/>
                    <measurement group_id="O5" value="0.237" lower_limit="0.173" upper_limit="0.323"/>
                    <measurement group_id="O6" value="0.250" lower_limit="0.167" upper_limit="0.373"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2, n=12, 6, 5, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.174" lower_limit="0.897" upper_limit="1.536"/>
                    <measurement group_id="O2" value="0.274" lower_limit="0.186" upper_limit="0.403"/>
                    <measurement group_id="O3" value="0.225" lower_limit="0.151" upper_limit="0.336"/>
                    <measurement group_id="O4" value="0.170" lower_limit="0.124" upper_limit="0.233"/>
                    <measurement group_id="O5" value="0.214" lower_limit="0.157" upper_limit="0.292"/>
                    <measurement group_id="O6" value="0.265" lower_limit="0.180" upper_limit="0.388"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=12, 6, 5, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.062" lower_limit="0.812" upper_limit="1.390"/>
                    <measurement group_id="O2" value="0.198" lower_limit="0.134" upper_limit="0.291"/>
                    <measurement group_id="O3" value="0.195" lower_limit="0.131" upper_limit="0.290"/>
                    <measurement group_id="O4" value="0.131" lower_limit="0.095" upper_limit="0.179"/>
                    <measurement group_id="O5" value="0.185" lower_limit="0.135" upper_limit="0.252"/>
                    <measurement group_id="O6" value="0.180" lower_limit="0.123" upper_limit="0.264"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8, n=12, 6, 6, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.095" lower_limit="0.837" upper_limit="1.434"/>
                    <measurement group_id="O2" value="0.201" lower_limit="0.137" upper_limit="0.296"/>
                    <measurement group_id="O3" value="0.129" lower_limit="0.088" upper_limit="0.189"/>
                    <measurement group_id="O4" value="0.102" lower_limit="0.075" upper_limit="0.140"/>
                    <measurement group_id="O5" value="0.126" lower_limit="0.092" upper_limit="0.172"/>
                    <measurement group_id="O6" value="0.178" lower_limit="0.121" upper_limit="0.261"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12, n=12, 5, 6, 9, 9, 5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.031" lower_limit="0.788" upper_limit="1.350"/>
                    <measurement group_id="O2" value="0.373" lower_limit="0.250" upper_limit="0.557"/>
                    <measurement group_id="O3" value="0.171" lower_limit="0.116" upper_limit="0.250"/>
                    <measurement group_id="O4" value="0.123" lower_limit="0.089" upper_limit="0.168"/>
                    <measurement group_id="O5" value="0.161" lower_limit="0.118" upper_limit="0.220"/>
                    <measurement group_id="O6" value="0.164" lower_limit="0.110" upper_limit="0.244"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18, n=12, 6, 6, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.079" lower_limit="0.824" upper_limit="1.412"/>
                    <measurement group_id="O2" value="0.466" lower_limit="0.317" upper_limit="0.685"/>
                    <measurement group_id="O3" value="0.314" lower_limit="0.214" upper_limit="0.460"/>
                    <measurement group_id="O4" value="0.152" lower_limit="0.111" upper_limit="0.208"/>
                    <measurement group_id="O5" value="0.139" lower_limit="0.102" upper_limit="0.190"/>
                    <measurement group_id="O6" value="0.179" lower_limit="0.122" upper_limit="0.262"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24, n=11, 6, 6, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.005" lower_limit="0.763" upper_limit="1.322"/>
                    <measurement group_id="O2" value="0.661" lower_limit="0.449" upper_limit="0.972"/>
                    <measurement group_id="O3" value="0.563" lower_limit="0.384" upper_limit="0.825"/>
                    <measurement group_id="O4" value="0.285" lower_limit="0.208" upper_limit="0.391"/>
                    <measurement group_id="O5" value="0.149" lower_limit="0.109" upper_limit="0.203"/>
                    <measurement group_id="O6" value="0.202" lower_limit="0.137" upper_limit="0.296"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26, n=12, 6, 6, 9, 9, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.119" lower_limit="0.855" upper_limit="1.464"/>
                    <measurement group_id="O2" value="0.776" lower_limit="0.527" upper_limit="1.141"/>
                    <measurement group_id="O3" value="0.663" lower_limit="0.452" upper_limit="0.972"/>
                    <measurement group_id="O4" value="0.317" lower_limit="0.231" upper_limit="0.435"/>
                    <measurement group_id="O5" value="0.199" lower_limit="0.146" upper_limit="0.271"/>
                    <measurement group_id="O6" value="0.186" lower_limit="0.127" upper_limit="0.273"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32, n=6, 6, 6, 0, 0, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.912" lower_limit="0.656" upper_limit="1.268"/>
                    <measurement group_id="O2" value="0.968" lower_limit="0.655" upper_limit="1.430"/>
                    <measurement group_id="O3" value="0.837" lower_limit="0.569" upper_limit="1.229"/>
                    <measurement group_id="O6" value="0.210" lower_limit="0.142" upper_limit="0.308"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36, n=6, 0, 0, 9, 9, 0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.975" lower_limit="0.691" upper_limit="1.376"/>
                    <measurement group_id="O4" value="0.858" lower_limit="0.624" upper_limit="1.180"/>
                    <measurement group_id="O5" value="0.374" lower_limit="0.274" upper_limit="0.511"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40, n=2, 0, 0, 0, 0, 6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.210" lower_limit="0.604" upper_limit="2.422"/>
                    <measurement group_id="O6" value="0.258" lower_limit="0.172" upper_limit="0.387"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Number of Participants With Anti-drug Antibody (ADA) Binding to GSK3511294</title>
        <description>Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. The results were categorized as negative, transient positive (defined as a single confirmatory positive immunogenic response that does not occur at the final study assessment) and persistent positive (defined as a confirmatory positive immunogenic response for at least 2 consecutive assessments or a single result at the final study assessment).</description>
        <time_frame>Up to Week 40</time_frame>
        <population>Safety Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Anti-drug Antibody (ADA) Binding to GSK3511294</title>
          <description>Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. The results were categorized as negative, transient positive (defined as a single confirmatory positive immunogenic response that does not occur at the final study assessment) and persistent positive (defined as a confirmatory positive immunogenic response for at least 2 consecutive assessments or a single result at the final study assessment).</description>
          <population>Safety Population.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Negative</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="12"/>
                    <measurement group_id="O2" value="6"/>
                    <measurement group_id="O3" value="5"/>
                    <measurement group_id="O4" value="4"/>
                    <measurement group_id="O5" value="7"/>
                    <measurement group_id="O6" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transient positive</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Persistent positive</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="5"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Titers of Binding ADA to GSK3511294</title>
        <description>Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. Titer was only measured when a positive result was found.</description>
        <time_frame>Up to Week 40</time_frame>
        <population>Safety Population. Only participants with positive results for ADA were analyzed.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Titers of Binding ADA to GSK3511294</title>
          <description>Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. Titer was only measured when a positive result was found.</description>
          <population>Safety Population. Only participants with positive results for ADA were analyzed.</population>
          <units>Titer</units>
          <param>Median</param>
          <dispersion>Full Range</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="0"/>
                <count group_id="O2" value="0"/>
                <count group_id="O3" value="1"/>
                <count group_id="O4" value="5"/>
                <count group_id="O5" value="2"/>
                <count group_id="O6" value="1"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O3" value="80.0" lower_limit="80" upper_limit="80"/>
                    <measurement group_id="O4" value="160.0" lower_limit="80" upper_limit="320"/>
                    <measurement group_id="O5" value="80.0" lower_limit="80" upper_limit="80"/>
                    <measurement group_id="O6" value="80.0" lower_limit="80" upper_limit="320"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Clinical Chemistry Parameters Like Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), and Aspartate Aminotransferase (AST)</title>
        <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like ALP, AST and ALT. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Clinical Chemistry Parameters Like Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), and Aspartate Aminotransferase (AST)</title>
          <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like ALP, AST and ALT. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>International units per Liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>ALT, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="5.12"/>
                    <measurement group_id="O2" value="0.3" spread="3.56"/>
                    <measurement group_id="O3" value="4.0" spread="14.20"/>
                    <measurement group_id="O4" value="-1.6" spread="2.07"/>
                    <measurement group_id="O5" value="-0.1" spread="3.26"/>
                    <measurement group_id="O6" value="-0.7" spread="2.73"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="5.96"/>
                    <measurement group_id="O2" value="2.5" spread="8.17"/>
                    <measurement group_id="O3" value="5.3" spread="17.94"/>
                    <measurement group_id="O4" value="-0.6" spread="2.51"/>
                    <measurement group_id="O5" value="-1.0" spread="3.20"/>
                    <measurement group_id="O6" value="1.2" spread="4.96"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0" spread="5.85"/>
                    <measurement group_id="O2" value="3.3" spread="11.08"/>
                    <measurement group_id="O3" value="4.2" spread="13.83"/>
                    <measurement group_id="O4" value="-1.2" spread="1.86"/>
                    <measurement group_id="O5" value="-0.1" spread="2.71"/>
                    <measurement group_id="O6" value="1.2" spread="3.43"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.7" spread="7.96"/>
                    <measurement group_id="O2" value="2.0" spread="9.74"/>
                    <measurement group_id="O3" value="2.3" spread="8.91"/>
                    <measurement group_id="O4" value="-0.6" spread="3.64"/>
                    <measurement group_id="O5" value="0.2" spread="3.42"/>
                    <measurement group_id="O6" value="4.5" spread="5.32"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.2" spread="7.76"/>
                    <measurement group_id="O2" value="1.3" spread="5.92"/>
                    <measurement group_id="O3" value="2.8" spread="7.36"/>
                    <measurement group_id="O4" value="0.7" spread="3.61"/>
                    <measurement group_id="O5" value="0.6" spread="4.98"/>
                    <measurement group_id="O6" value="1.2" spread="5.54"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="5.57"/>
                    <measurement group_id="O2" value="-5.3" spread="7.97"/>
                    <measurement group_id="O3" value="-1.3" spread="4.32"/>
                    <measurement group_id="O4" value="0.3" spread="4.85"/>
                    <measurement group_id="O5" value="-2.3" spread="4.97"/>
                    <measurement group_id="O6" value="3.0" spread="2.53"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="6.43"/>
                    <measurement group_id="O2" value="-4.3" spread="7.63"/>
                    <measurement group_id="O3" value="0.7" spread="4.23"/>
                    <measurement group_id="O4" value="1.4" spread="9.41"/>
                    <measurement group_id="O5" value="-2.6" spread="2.55"/>
                    <measurement group_id="O6" value="-2.8" spread="4.36"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="7.25"/>
                    <measurement group_id="O2" value="-3.3" spread="10.39"/>
                    <measurement group_id="O3" value="2.5" spread="6.53"/>
                    <measurement group_id="O4" value="-1.6" spread="3.40"/>
                    <measurement group_id="O5" value="1.8" spread="9.56"/>
                    <measurement group_id="O6" value="-3.0" spread="4.77"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.9" spread="6.07"/>
                    <measurement group_id="O2" value="-1.7" spread="4.18"/>
                    <measurement group_id="O3" value="0.5" spread="3.94"/>
                    <measurement group_id="O4" value="-0.4" spread="1.94"/>
                    <measurement group_id="O5" value="3.0" spread="5.12"/>
                    <measurement group_id="O6" value="-0.7" spread="2.66"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="6.13"/>
                    <measurement group_id="O2" value="-3.5" spread="7.56"/>
                    <measurement group_id="O3" value="1.0" spread="10.30"/>
                    <measurement group_id="O4" value="1.9" spread="8.81"/>
                    <measurement group_id="O5" value="4.4" spread="6.93"/>
                    <measurement group_id="O6" value="-0.7" spread="5.20"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="12.11"/>
                    <measurement group_id="O2" value="-3.5" spread="7.64"/>
                    <measurement group_id="O3" value="5.2" spread="14.18"/>
                    <measurement group_id="O4" value="2.2" spread="10.76"/>
                    <measurement group_id="O5" value="7.3" spread="12.97"/>
                    <measurement group_id="O6" value="0.8" spread="5.34"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.1" spread="6.13"/>
                    <measurement group_id="O2" value="-0.8" spread="6.79"/>
                    <measurement group_id="O3" value="-0.5" spread="6.47"/>
                    <measurement group_id="O4" value="5.1" spread="19.63"/>
                    <measurement group_id="O5" value="6.2" spread="13.08"/>
                    <measurement group_id="O6" value="2.5" spread="7.87"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.5" spread="8.04"/>
                    <measurement group_id="O2" value="-1.7" spread="9.89"/>
                    <measurement group_id="O3" value="-1.0" spread="3.29"/>
                    <measurement group_id="O6" value="-3.0" spread="4.60"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="8.29"/>
                    <measurement group_id="O4" value="1.3" spread="6.86"/>
                    <measurement group_id="O5" value="5.0" spread="7.84"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALT, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.5" spread="7.78"/>
                    <measurement group_id="O6" value="1.2" spread="8.08"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.5" spread="3.55"/>
                    <measurement group_id="O2" value="-1.2" spread="2.48"/>
                    <measurement group_id="O3" value="-0.8" spread="7.19"/>
                    <measurement group_id="O4" value="-2.6" spread="4.28"/>
                    <measurement group_id="O5" value="-3.9" spread="5.42"/>
                    <measurement group_id="O6" value="-3.7" spread="3.88"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.8" spread="4.86"/>
                    <measurement group_id="O2" value="-0.8" spread="4.62"/>
                    <measurement group_id="O3" value="-1.2" spread="7.22"/>
                    <measurement group_id="O4" value="-1.8" spread="3.80"/>
                    <measurement group_id="O5" value="-5.6" spread="6.58"/>
                    <measurement group_id="O6" value="-3.2" spread="4.79"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.3" spread="4.27"/>
                    <measurement group_id="O2" value="-0.8" spread="5.08"/>
                    <measurement group_id="O3" value="-2.0" spread="4.34"/>
                    <measurement group_id="O4" value="-2.9" spread="2.93"/>
                    <measurement group_id="O5" value="-4.9" spread="6.33"/>
                    <measurement group_id="O6" value="-3.3" spread="4.93"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.6" spread="4.10"/>
                    <measurement group_id="O2" value="-0.5" spread="5.28"/>
                    <measurement group_id="O3" value="-1.7" spread="3.67"/>
                    <measurement group_id="O4" value="-3.2" spread="3.31"/>
                    <measurement group_id="O5" value="-3.7" spread="7.57"/>
                    <measurement group_id="O6" value="-2.0" spread="5.83"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="4.12"/>
                    <measurement group_id="O2" value="0.0" spread="3.74"/>
                    <measurement group_id="O3" value="-0.2" spread="2.32"/>
                    <measurement group_id="O4" value="-1.9" spread="2.85"/>
                    <measurement group_id="O5" value="-3.3" spread="4.53"/>
                    <measurement group_id="O6" value="-4.6" spread="4.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="4.66"/>
                    <measurement group_id="O2" value="-0.3" spread="4.55"/>
                    <measurement group_id="O3" value="-2.5" spread="2.88"/>
                    <measurement group_id="O4" value="1.0" spread="9.19"/>
                    <measurement group_id="O5" value="-3.8" spread="6.44"/>
                    <measurement group_id="O6" value="-0.7" spread="4.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.5" spread="3.97"/>
                    <measurement group_id="O2" value="-2.3" spread="3.83"/>
                    <measurement group_id="O3" value="0.0" spread="6.03"/>
                    <measurement group_id="O4" value="0.0" spread="4.90"/>
                    <measurement group_id="O5" value="-4.3" spread="6.87"/>
                    <measurement group_id="O6" value="-4.2" spread="5.91"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.9" spread="7.45"/>
                    <measurement group_id="O2" value="-1.8" spread="3.66"/>
                    <measurement group_id="O3" value="0.5" spread="3.02"/>
                    <measurement group_id="O4" value="-0.2" spread="3.77"/>
                    <measurement group_id="O5" value="-1.0" spread="10.58"/>
                    <measurement group_id="O6" value="-4.7" spread="4.50"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="2.79"/>
                    <measurement group_id="O2" value="-1.2" spread="1.94"/>
                    <measurement group_id="O3" value="1.2" spread="3.71"/>
                    <measurement group_id="O4" value="-1.2" spread="2.17"/>
                    <measurement group_id="O5" value="-1.4" spread="6.98"/>
                    <measurement group_id="O6" value="-2.0" spread="5.83"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="4.14"/>
                    <measurement group_id="O2" value="-1.2" spread="2.86"/>
                    <measurement group_id="O3" value="1.3" spread="10.09"/>
                    <measurement group_id="O4" value="-0.7" spread="3.64"/>
                    <measurement group_id="O5" value="-1.8" spread="5.56"/>
                    <measurement group_id="O6" value="-3.3" spread="5.61"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.2" spread="18.52"/>
                    <measurement group_id="O2" value="1.3" spread="2.73"/>
                    <measurement group_id="O3" value="0.8" spread="5.42"/>
                    <measurement group_id="O4" value="-1.1" spread="5.64"/>
                    <measurement group_id="O5" value="-2.8" spread="8.76"/>
                    <measurement group_id="O6" value="-1.8" spread="3.06"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="4.08"/>
                    <measurement group_id="O2" value="1.8" spread="1.60"/>
                    <measurement group_id="O3" value="0.2" spread="3.37"/>
                    <measurement group_id="O4" value="0.0" spread="7.00"/>
                    <measurement group_id="O5" value="0.1" spread="9.21"/>
                    <measurement group_id="O6" value="0.2" spread="3.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="3.39"/>
                    <measurement group_id="O2" value="0.5" spread="3.33"/>
                    <measurement group_id="O3" value="-2.5" spread="1.52"/>
                    <measurement group_id="O6" value="-3.5" spread="5.47"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.0" spread="4.69"/>
                    <measurement group_id="O4" value="-2.0" spread="4.36"/>
                    <measurement group_id="O5" value="-3.2" spread="6.70"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>AST, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-7.5" spread="6.36"/>
                    <measurement group_id="O6" value="3.0" spread="13.24"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="4.84"/>
                    <measurement group_id="O2" value="-3.3" spread="1.37"/>
                    <measurement group_id="O3" value="1.0" spread="4.18"/>
                    <measurement group_id="O4" value="-4.9" spread="2.80"/>
                    <measurement group_id="O5" value="1.3" spread="7.28"/>
                    <measurement group_id="O6" value="-1.5" spread="7.77"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="5.66"/>
                    <measurement group_id="O2" value="-2.7" spread="2.94"/>
                    <measurement group_id="O3" value="0.3" spread="8.52"/>
                    <measurement group_id="O4" value="-1.8" spread="3.99"/>
                    <measurement group_id="O5" value="-0.6" spread="5.32"/>
                    <measurement group_id="O6" value="0.2" spread="5.88"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="5.30"/>
                    <measurement group_id="O2" value="-1.3" spread="3.20"/>
                    <measurement group_id="O3" value="0.0" spread="9.17"/>
                    <measurement group_id="O4" value="-1.9" spread="3.62"/>
                    <measurement group_id="O5" value="-0.2" spread="6.34"/>
                    <measurement group_id="O6" value="-1.3" spread="6.09"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="5.74"/>
                    <measurement group_id="O2" value="-2.0" spread="3.52"/>
                    <measurement group_id="O3" value="0.3" spread="4.76"/>
                    <measurement group_id="O4" value="-1.4" spread="5.25"/>
                    <measurement group_id="O5" value="1.9" spread="9.44"/>
                    <measurement group_id="O6" value="-1.2" spread="5.12"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 1,n=12,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2" spread="5.86"/>
                    <measurement group_id="O2" value="-2.2" spread="5.56"/>
                    <measurement group_id="O3" value="-2.5" spread="6.06"/>
                    <measurement group_id="O4" value="-0.7" spread="6.18"/>
                    <measurement group_id="O5" value="-1.1" spread="4.62"/>
                    <measurement group_id="O6" value="-1.2" spread="7.53"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0" spread="3.44"/>
                    <measurement group_id="O2" value="-8.2" spread="6.52"/>
                    <measurement group_id="O3" value="-4.2" spread="3.54"/>
                    <measurement group_id="O4" value="-0.6" spread="3.91"/>
                    <measurement group_id="O5" value="3.1" spread="5.25"/>
                    <measurement group_id="O6" value="-1.0" spread="8.32"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" spread="4.81"/>
                    <measurement group_id="O2" value="-8.2" spread="8.30"/>
                    <measurement group_id="O3" value="-1.2" spread="3.97"/>
                    <measurement group_id="O4" value="-3.2" spread="4.32"/>
                    <measurement group_id="O5" value="2.6" spread="5.50"/>
                    <measurement group_id="O6" value="-2.2" spread="7.81"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.9" spread="6.88"/>
                    <measurement group_id="O2" value="-2.0" spread="4.82"/>
                    <measurement group_id="O3" value="1.0" spread="10.06"/>
                    <measurement group_id="O4" value="-4.4" spread="4.03"/>
                    <measurement group_id="O5" value="3.7" spread="3.61"/>
                    <measurement group_id="O6" value="-0.8" spread="8.30"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="6.43"/>
                    <measurement group_id="O2" value="-4.3" spread="7.09"/>
                    <measurement group_id="O3" value="7.2" spread="10.46"/>
                    <measurement group_id="O4" value="-2.8" spread="2.82"/>
                    <measurement group_id="O5" value="3.1" spread="11.58"/>
                    <measurement group_id="O6" value="-0.3" spread="5.09"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.1" spread="6.82"/>
                    <measurement group_id="O2" value="-2.0" spread="6.48"/>
                    <measurement group_id="O3" value="-1.7" spread="4.84"/>
                    <measurement group_id="O4" value="1.9" spread="6.79"/>
                    <measurement group_id="O5" value="3.8" spread="8.27"/>
                    <measurement group_id="O6" value="-3.5" spread="6.80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.8" spread="12.21"/>
                    <measurement group_id="O2" value="-1.2" spread="7.94"/>
                    <measurement group_id="O3" value="-1.0" spread="4.73"/>
                    <measurement group_id="O4" value="1.2" spread="10.51"/>
                    <measurement group_id="O5" value="5.8" spread="8.39"/>
                    <measurement group_id="O6" value="-0.7" spread="6.74"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.2" spread="8.64"/>
                    <measurement group_id="O2" value="-6.2" spread="8.30"/>
                    <measurement group_id="O3" value="-2.2" spread="4.02"/>
                    <measurement group_id="O4" value="0.4" spread="10.75"/>
                    <measurement group_id="O5" value="4.8" spread="8.24"/>
                    <measurement group_id="O6" value="-1.7" spread="6.02"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="8.51"/>
                    <measurement group_id="O2" value="-3.3" spread="8.50"/>
                    <measurement group_id="O3" value="0.2" spread="5.31"/>
                    <measurement group_id="O6" value="-1.0" spread="7.72"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="9.0" spread="15.57"/>
                    <measurement group_id="O4" value="-0.6" spread="11.19"/>
                    <measurement group_id="O5" value="7.2" spread="8.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>ALP, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.5" spread="0.71"/>
                    <measurement group_id="O6" value="-3.7" spread="9.48"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Change From Baseline in Clinical Chemistry Parameter Like Glucose, Calcium, Potassium, Sodium, Blood Urea Nitrogen (BUN), and Magnesium</title>
        <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like glucose, calcium, potassium, sodium, BUN, and magnesium. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Change From Baseline in Clinical Chemistry Parameter Like Glucose, Calcium, Potassium, Sodium, Blood Urea Nitrogen (BUN), and Magnesium</title>
          <description>Blood samples were collected at indicated time-points for analysis of clinical parameters like glucose, calcium, potassium, sodium, BUN, and magnesium. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Millimoles per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Glucose, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.06" spread="0.912"/>
                    <measurement group_id="O2" value="-0.13" spread="0.418"/>
                    <measurement group_id="O3" value="0.14" spread="0.439"/>
                    <measurement group_id="O4" value="-0.11" spread="0.533"/>
                    <measurement group_id="O5" value="-0.72" spread="0.948"/>
                    <measurement group_id="O6" value="0.20" spread="0.352"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.28" spread="0.673"/>
                    <measurement group_id="O2" value="-0.10" spread="1.215"/>
                    <measurement group_id="O3" value="-0.93" spread="1.117"/>
                    <measurement group_id="O4" value="-0.18" spread="0.455"/>
                    <measurement group_id="O5" value="-0.21" spread="0.647"/>
                    <measurement group_id="O6" value="0.15" spread="0.521"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.11" spread="0.712"/>
                    <measurement group_id="O2" value="0.12" spread="0.987"/>
                    <measurement group_id="O3" value="-0.33" spread="0.857"/>
                    <measurement group_id="O4" value="0.26" spread="0.940"/>
                    <measurement group_id="O5" value="-0.34" spread="1.364"/>
                    <measurement group_id="O6" value="0.50" spread="1.103"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.06" spread="0.647"/>
                    <measurement group_id="O2" value="-0.07" spread="0.612"/>
                    <measurement group_id="O3" value="0.28" spread="0.958"/>
                    <measurement group_id="O4" value="0.01" spread="0.775"/>
                    <measurement group_id="O5" value="-0.17" spread="0.728"/>
                    <measurement group_id="O6" value="0.05" spread="0.539"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.00" spread="0.656"/>
                    <measurement group_id="O2" value="-0.35" spread="0.394"/>
                    <measurement group_id="O3" value="-0.18" spread="1.280"/>
                    <measurement group_id="O4" value="-0.20" spread="0.624"/>
                    <measurement group_id="O5" value="-0.23" spread="1.015"/>
                    <measurement group_id="O6" value="0.50" spread="1.345"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.03" spread="0.396"/>
                    <measurement group_id="O2" value="-0.05" spread="0.295"/>
                    <measurement group_id="O3" value="0.00" spread="0.525"/>
                    <measurement group_id="O4" value="-0.02" spread="1.027"/>
                    <measurement group_id="O5" value="-0.18" spread="0.902"/>
                    <measurement group_id="O6" value="-0.10" spread="0.155"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.19" spread="0.783"/>
                    <measurement group_id="O2" value="-0.33" spread="0.543"/>
                    <measurement group_id="O3" value="0.03" spread="0.582"/>
                    <measurement group_id="O4" value="-0.28" spread="0.678"/>
                    <measurement group_id="O5" value="-0.08" spread="0.919"/>
                    <measurement group_id="O6" value="0.33" spread="0.476"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.06" spread="0.444"/>
                    <measurement group_id="O2" value="-0.42" spread="0.585"/>
                    <measurement group_id="O3" value="0.27" spread="0.824"/>
                    <measurement group_id="O4" value="0.04" spread="0.430"/>
                    <measurement group_id="O5" value="-0.36" spread="1.193"/>
                    <measurement group_id="O6" value="0.42" spread="0.722"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.32" spread="0.606"/>
                    <measurement group_id="O2" value="-0.15" spread="0.428"/>
                    <measurement group_id="O3" value="0.13" spread="1.093"/>
                    <measurement group_id="O4" value="0.08" spread="0.905"/>
                    <measurement group_id="O5" value="-0.66" spread="0.760"/>
                    <measurement group_id="O6" value="0.23" spread="0.432"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.03" spread="0.548"/>
                    <measurement group_id="O2" value="-0.02" spread="0.331"/>
                    <measurement group_id="O3" value="0.42" spread="1.017"/>
                    <measurement group_id="O4" value="-0.17" spread="0.541"/>
                    <measurement group_id="O5" value="-0.23" spread="0.825"/>
                    <measurement group_id="O6" value="0.15" spread="0.288"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.38" spread="1.131"/>
                    <measurement group_id="O2" value="-0.13" spread="0.333"/>
                    <measurement group_id="O3" value="0.02" spread="0.773"/>
                    <measurement group_id="O4" value="-0.27" spread="0.654"/>
                    <measurement group_id="O5" value="-0.26" spread="0.928"/>
                    <measurement group_id="O6" value="0.50" spread="0.590"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.18" spread="0.506"/>
                    <measurement group_id="O2" value="-0.10" spread="0.346"/>
                    <measurement group_id="O3" value="0.62" spread="1.144"/>
                    <measurement group_id="O4" value="-0.09" spread="0.362"/>
                    <measurement group_id="O5" value="-0.22" spread="0.758"/>
                    <measurement group_id="O6" value="0.38" spread="0.445"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.40" spread="1.233"/>
                    <measurement group_id="O2" value="0.02" spread="0.194"/>
                    <measurement group_id="O3" value="-0.28" spread="0.703"/>
                    <measurement group_id="O6" value="0.32" spread="0.354"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.17" spread="0.493"/>
                    <measurement group_id="O4" value="-0.26" spread="0.436"/>
                    <measurement group_id="O5" value="-0.07" spread="0.996"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.40" spread="0.566"/>
                    <measurement group_id="O6" value="0.23" spread="0.769"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.025" spread="0.0645"/>
                    <measurement group_id="O2" value="-0.027" spread="0.0615"/>
                    <measurement group_id="O3" value="-0.004" spread="0.0865"/>
                    <measurement group_id="O4" value="-0.049" spread="0.0736"/>
                    <measurement group_id="O5" value="0.016" spread="0.1207"/>
                    <measurement group_id="O6" value="0.043" spread="0.0480"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.008" spread="0.0833"/>
                    <measurement group_id="O2" value="-0.033" spread="0.1009"/>
                    <measurement group_id="O3" value="0.027" spread="0.1041"/>
                    <measurement group_id="O4" value="-0.011" spread="0.0756"/>
                    <measurement group_id="O5" value="-0.022" spread="0.1012"/>
                    <measurement group_id="O6" value="0.070" spread="0.0415"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.012" spread="0.0658"/>
                    <measurement group_id="O2" value="-0.017" spread="0.0612"/>
                    <measurement group_id="O3" value="0.017" spread="0.0794"/>
                    <measurement group_id="O4" value="-0.033" spread="0.0762"/>
                    <measurement group_id="O5" value="-0.007" spread="0.0714"/>
                    <measurement group_id="O6" value="0.073" spread="0.0301"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.023" spread="0.0738"/>
                    <measurement group_id="O2" value="-0.050" spread="0.0846"/>
                    <measurement group_id="O3" value="0.003" spread="0.0942"/>
                    <measurement group_id="O4" value="-0.040" spread="0.0640"/>
                    <measurement group_id="O5" value="-0.031" spread="0.0933"/>
                    <measurement group_id="O6" value="0.043" spread="0.0843"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.009" spread="0.0745"/>
                    <measurement group_id="O2" value="-0.047" spread="0.0723"/>
                    <measurement group_id="O3" value="0.017" spread="0.0916"/>
                    <measurement group_id="O4" value="-0.044" spread="0.0847"/>
                    <measurement group_id="O5" value="-0.029" spread="0.0657"/>
                    <measurement group_id="O6" value="-0.040" spread="0.0663"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="0.0634"/>
                    <measurement group_id="O2" value="-0.013" spread="0.0547"/>
                    <measurement group_id="O3" value="-0.033" spread="0.0855"/>
                    <measurement group_id="O4" value="-0.002" spread="0.0863"/>
                    <measurement group_id="O5" value="0.062" spread="0.0771"/>
                    <measurement group_id="O6" value="0.013" spread="0.0163"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.040" spread="0.0615"/>
                    <measurement group_id="O2" value="-0.027" spread="0.0766"/>
                    <measurement group_id="O3" value="-0.013" spread="0.1198"/>
                    <measurement group_id="O4" value="-0.031" spread="0.0729"/>
                    <measurement group_id="O5" value="0.022" spread="0.0977"/>
                    <measurement group_id="O6" value="0.033" spread="0.0301"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0621"/>
                    <measurement group_id="O2" value="-0.007" spread="0.1171"/>
                    <measurement group_id="O3" value="-0.003" spread="0.0898"/>
                    <measurement group_id="O4" value="-0.024" spread="0.0767"/>
                    <measurement group_id="O5" value="0.031" spread="0.0906"/>
                    <measurement group_id="O6" value="-0.003" spread="0.0612"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.017" spread="0.0489"/>
                    <measurement group_id="O2" value="-0.060" spread="0.0657"/>
                    <measurement group_id="O3" value="-0.003" spread="0.1274"/>
                    <measurement group_id="O4" value="-0.020" spread="0.0755"/>
                    <measurement group_id="O5" value="0.036" spread="0.0581"/>
                    <measurement group_id="O6" value="-0.003" spread="0.0794"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.003" spread="0.0918"/>
                    <measurement group_id="O2" value="-0.013" spread="0.0826"/>
                    <measurement group_id="O3" value="-0.033" spread="0.0845"/>
                    <measurement group_id="O4" value="0.007" spread="0.0860"/>
                    <measurement group_id="O5" value="0.031" spread="0.0801"/>
                    <measurement group_id="O6" value="0.010" spread="0.0690"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.035" spread="0.0452"/>
                    <measurement group_id="O2" value="-0.053" spread="0.0677"/>
                    <measurement group_id="O3" value="0.007" spread="0.0864"/>
                    <measurement group_id="O4" value="-0.016" spread="0.0942"/>
                    <measurement group_id="O5" value="0.022" spread="0.1218"/>
                    <measurement group_id="O6" value="0.027" spread="0.0797"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.018" spread="0.0731"/>
                    <measurement group_id="O2" value="-0.067" spread="0.0532"/>
                    <measurement group_id="O3" value="-0.017" spread="0.1255"/>
                    <measurement group_id="O4" value="-0.056" spread="0.0260"/>
                    <measurement group_id="O5" value="0.013" spread="0.0529"/>
                    <measurement group_id="O6" value="-0.010" spread="0.0767"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.020" spread="0.1020"/>
                    <measurement group_id="O2" value="0.027" spread="0.0776"/>
                    <measurement group_id="O3" value="0.020" spread="0.0867"/>
                    <measurement group_id="O6" value="0.010" spread="0.0724"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0607"/>
                    <measurement group_id="O4" value="-0.013" spread="0.0624"/>
                    <measurement group_id="O5" value="0.029" spread="0.0813"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.1131"/>
                    <measurement group_id="O6" value="0.043" spread="0.0774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.03" spread="0.230"/>
                    <measurement group_id="O2" value="0.02" spread="0.179"/>
                    <measurement group_id="O3" value="0.44" spread="0.365"/>
                    <measurement group_id="O4" value="0.06" spread="0.397"/>
                    <measurement group_id="O5" value="0.18" spread="0.307"/>
                    <measurement group_id="O6" value="0.17" spread="0.234"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.07" spread="0.290"/>
                    <measurement group_id="O2" value="0.03" spread="0.258"/>
                    <measurement group_id="O3" value="0.02" spread="0.204"/>
                    <measurement group_id="O4" value="0.14" spread="0.332"/>
                    <measurement group_id="O5" value="0.01" spread="0.136"/>
                    <measurement group_id="O6" value="0.12" spread="0.194"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.13" spread="0.196"/>
                    <measurement group_id="O2" value="0.05" spread="0.472"/>
                    <measurement group_id="O3" value="0.08" spread="0.232"/>
                    <measurement group_id="O4" value="0.03" spread="0.218"/>
                    <measurement group_id="O5" value="0.06" spread="0.246"/>
                    <measurement group_id="O6" value="0.27" spread="0.163"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.11" spread="0.303"/>
                    <measurement group_id="O2" value="0.10" spread="0.276"/>
                    <measurement group_id="O3" value="0.00" spread="0.126"/>
                    <measurement group_id="O4" value="0.11" spread="0.267"/>
                    <measurement group_id="O5" value="0.04" spread="0.207"/>
                    <measurement group_id="O6" value="0.15" spread="0.217"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.02" spread="0.340"/>
                    <measurement group_id="O2" value="0.05" spread="0.451"/>
                    <measurement group_id="O3" value="0.18" spread="0.194"/>
                    <measurement group_id="O4" value="0.22" spread="0.342"/>
                    <measurement group_id="O5" value="0.07" spread="0.300"/>
                    <measurement group_id="O6" value="0.00" spread="0.200"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.00" spread="0.316"/>
                    <measurement group_id="O2" value="0.05" spread="0.315"/>
                    <measurement group_id="O3" value="0.20" spread="0.341"/>
                    <measurement group_id="O4" value="-0.04" spread="0.201"/>
                    <measurement group_id="O5" value="0.09" spread="0.352"/>
                    <measurement group_id="O6" value="0.02" spread="0.299"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.00" spread="0.276"/>
                    <measurement group_id="O2" value="-0.07" spread="0.372"/>
                    <measurement group_id="O3" value="0.27" spread="0.344"/>
                    <measurement group_id="O4" value="-0.04" spread="0.283"/>
                    <measurement group_id="O5" value="0.11" spread="0.196"/>
                    <measurement group_id="O6" value="0.00" spread="0.276"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.18" spread="0.234"/>
                    <measurement group_id="O2" value="0.00" spread="0.352"/>
                    <measurement group_id="O3" value="0.12" spread="0.117"/>
                    <measurement group_id="O4" value="0.00" spread="0.269"/>
                    <measurement group_id="O5" value="0.14" spread="0.207"/>
                    <measurement group_id="O6" value="-0.05" spread="0.207"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.02" spread="0.383"/>
                    <measurement group_id="O2" value="-0.02" spread="0.387"/>
                    <measurement group_id="O3" value="0.12" spread="0.331"/>
                    <measurement group_id="O4" value="0.00" spread="0.278"/>
                    <measurement group_id="O5" value="0.04" spread="0.213"/>
                    <measurement group_id="O6" value="0.03" spread="0.273"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.02" spread="0.343"/>
                    <measurement group_id="O2" value="0.00" spread="0.329"/>
                    <measurement group_id="O3" value="0.07" spread="0.234"/>
                    <measurement group_id="O4" value="0.03" spread="0.287"/>
                    <measurement group_id="O5" value="0.13" spread="0.308"/>
                    <measurement group_id="O6" value="0.02" spread="0.293"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.03" spread="0.458"/>
                    <measurement group_id="O2" value="-0.02" spread="0.397"/>
                    <measurement group_id="O3" value="0.03" spread="0.234"/>
                    <measurement group_id="O4" value="0.12" spread="0.291"/>
                    <measurement group_id="O5" value="-0.04" spread="0.260"/>
                    <measurement group_id="O6" value="0.07" spread="0.288"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.13" spread="0.360"/>
                    <measurement group_id="O2" value="-0.03" spread="0.480"/>
                    <measurement group_id="O3" value="0.00" spread="0.179"/>
                    <measurement group_id="O4" value="-0.01" spread="0.280"/>
                    <measurement group_id="O5" value="0.07" spread="0.235"/>
                    <measurement group_id="O6" value="0.07" spread="0.327"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.15" spread="0.476"/>
                    <measurement group_id="O2" value="0.03" spread="0.242"/>
                    <measurement group_id="O3" value="0.12" spread="0.223"/>
                    <measurement group_id="O6" value="0.12" spread="0.147"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.07" spread="0.121"/>
                    <measurement group_id="O4" value="0.08" spread="0.311"/>
                    <measurement group_id="O5" value="0.09" spread="0.215"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.35" spread="0.495"/>
                    <measurement group_id="O6" value="0.13" spread="0.356"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.8" spread="2.14"/>
                    <measurement group_id="O2" value="0.0" spread="1.90"/>
                    <measurement group_id="O3" value="0.0" spread="1.58"/>
                    <measurement group_id="O4" value="-0.3" spread="1.94"/>
                    <measurement group_id="O5" value="0.9" spread="1.76"/>
                    <measurement group_id="O6" value="1.8" spread="1.72"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.2" spread="1.75"/>
                    <measurement group_id="O2" value="0.0" spread="0.89"/>
                    <measurement group_id="O3" value="0.3" spread="1.21"/>
                    <measurement group_id="O4" value="0.4" spread="1.33"/>
                    <measurement group_id="O5" value="0.9" spread="1.96"/>
                    <measurement group_id="O6" value="2.0" spread="1.55"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="1.93"/>
                    <measurement group_id="O2" value="0.2" spread="1.60"/>
                    <measurement group_id="O3" value="0.0" spread="2.19"/>
                    <measurement group_id="O4" value="-0.8" spread="2.11"/>
                    <measurement group_id="O5" value="0.3" spread="1.32"/>
                    <measurement group_id="O6" value="1.3" spread="1.86"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.3" spread="1.66"/>
                    <measurement group_id="O2" value="1.7" spread="1.51"/>
                    <measurement group_id="O3" value="-1.3" spread="1.86"/>
                    <measurement group_id="O4" value="-0.2" spread="2.22"/>
                    <measurement group_id="O5" value="0.8" spread="2.05"/>
                    <measurement group_id="O6" value="1.7" spread="1.75"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.8" spread="2.14"/>
                    <measurement group_id="O2" value="0.8" spread="2.32"/>
                    <measurement group_id="O3" value="-1.7" spread="1.03"/>
                    <measurement group_id="O4" value="0.1" spread="1.45"/>
                    <measurement group_id="O5" value="-0.1" spread="1.69"/>
                    <measurement group_id="O6" value="0.4" spread="2.19"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="1.51"/>
                    <measurement group_id="O2" value="1.0" spread="1.26"/>
                    <measurement group_id="O3" value="-0.7" spread="1.51"/>
                    <measurement group_id="O4" value="0.0" spread="1.32"/>
                    <measurement group_id="O5" value="-0.3" spread="1.66"/>
                    <measurement group_id="O6" value="1.0" spread="2.28"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="2.04"/>
                    <measurement group_id="O2" value="1.0" spread="1.41"/>
                    <measurement group_id="O3" value="-1.2" spread="0.98"/>
                    <measurement group_id="O4" value="-1.2" spread="1.30"/>
                    <measurement group_id="O5" value="-0.6" spread="1.67"/>
                    <measurement group_id="O6" value="1.0" spread="1.41"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="1.93"/>
                    <measurement group_id="O2" value="0.0" spread="2.53"/>
                    <measurement group_id="O3" value="-0.5" spread="1.52"/>
                    <measurement group_id="O4" value="-0.7" spread="1.94"/>
                    <measurement group_id="O5" value="-1.1" spread="1.05"/>
                    <measurement group_id="O6" value="1.5" spread="3.45"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="2.00"/>
                    <measurement group_id="O2" value="1.0" spread="1.26"/>
                    <measurement group_id="O3" value="-0.8" spread="1.47"/>
                    <measurement group_id="O4" value="-0.2" spread="1.56"/>
                    <measurement group_id="O5" value="-0.3" spread="1.22"/>
                    <measurement group_id="O6" value="1.3" spread="2.25"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="1.51"/>
                    <measurement group_id="O2" value="-0.7" spread="2.25"/>
                    <measurement group_id="O3" value="-1.0" spread="1.10"/>
                    <measurement group_id="O4" value="-0.7" spread="1.22"/>
                    <measurement group_id="O5" value="0.0" spread="1.66"/>
                    <measurement group_id="O6" value="0.8" spread="1.60"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="2.02"/>
                    <measurement group_id="O2" value="-0.2" spread="1.60"/>
                    <measurement group_id="O3" value="-1.5" spread="1.22"/>
                    <measurement group_id="O4" value="-0.9" spread="2.37"/>
                    <measurement group_id="O5" value="0.2" spread="1.64"/>
                    <measurement group_id="O6" value="1.2" spread="1.72"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2" spread="1.40"/>
                    <measurement group_id="O2" value="0.0" spread="1.90"/>
                    <measurement group_id="O3" value="-0.7" spread="2.88"/>
                    <measurement group_id="O4" value="-1.1" spread="2.15"/>
                    <measurement group_id="O5" value="-1.1" spread="1.54"/>
                    <measurement group_id="O6" value="1.7" spread="1.97"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="2.25"/>
                    <measurement group_id="O2" value="0.5" spread="3.56"/>
                    <measurement group_id="O3" value="-1.8" spread="1.17"/>
                    <measurement group_id="O6" value="0.7" spread="2.07"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="2.66"/>
                    <measurement group_id="O4" value="-0.9" spread="1.90"/>
                    <measurement group_id="O5" value="-1.3" spread="1.00"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="2.12"/>
                    <measurement group_id="O6" value="0.0" spread="1.90"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.020" spread="0.0467"/>
                    <measurement group_id="O2" value="-0.037" spread="0.0585"/>
                    <measurement group_id="O3" value="0.008" spread="0.0642"/>
                    <measurement group_id="O4" value="0.000" spread="0.0361"/>
                    <measurement group_id="O5" value="-0.036" spread="0.0623"/>
                    <measurement group_id="O6" value="-0.020" spread="0.0310"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.012" spread="0.0542"/>
                    <measurement group_id="O2" value="-0.043" spread="0.0388"/>
                    <measurement group_id="O3" value="-0.003" spread="0.0709"/>
                    <measurement group_id="O4" value="0.007" spread="0.0283"/>
                    <measurement group_id="O5" value="-0.064" spread="0.0564"/>
                    <measurement group_id="O6" value="-0.037" spread="0.0427"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="0.0750"/>
                    <measurement group_id="O2" value="-0.020" spread="0.0310"/>
                    <measurement group_id="O3" value="-0.007" spread="0.0575"/>
                    <measurement group_id="O4" value="-0.007" spread="0.0283"/>
                    <measurement group_id="O5" value="-0.060" spread="0.0490"/>
                    <measurement group_id="O6" value="-0.047" spread="0.0628"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.017" spread="0.0545"/>
                    <measurement group_id="O2" value="-0.047" spread="0.0745"/>
                    <measurement group_id="O3" value="-0.033" spread="0.0413"/>
                    <measurement group_id="O4" value="0.007" spread="0.0283"/>
                    <measurement group_id="O5" value="-0.036" spread="0.0536"/>
                    <measurement group_id="O6" value="-0.020" spread="0.0632"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.0427"/>
                    <measurement group_id="O2" value="-0.003" spread="0.0638"/>
                    <measurement group_id="O3" value="0.017" spread="0.0480"/>
                    <measurement group_id="O4" value="-0.007" spread="0.0520"/>
                    <measurement group_id="O5" value="-0.040" spread="0.0346"/>
                    <measurement group_id="O6" value="-0.032" spread="0.0460"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.005" spread="0.0410"/>
                    <measurement group_id="O2" value="-0.003" spread="0.0513"/>
                    <measurement group_id="O3" value="0.033" spread="0.0484"/>
                    <measurement group_id="O4" value="0.018" spread="0.0570"/>
                    <measurement group_id="O5" value="-0.036" spread="0.0445"/>
                    <measurement group_id="O6" value="-0.027" spread="0.0501"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.007" spread="0.0345"/>
                    <measurement group_id="O2" value="-0.033" spread="0.0589"/>
                    <measurement group_id="O3" value="0.000" spread="0.0456"/>
                    <measurement group_id="O4" value="0.007" spread="0.0346"/>
                    <measurement group_id="O5" value="-0.027" spread="0.0529"/>
                    <measurement group_id="O6" value="-0.017" spread="0.0408"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.003" spread="0.0608"/>
                    <measurement group_id="O2" value="-0.027" spread="0.0501"/>
                    <measurement group_id="O3" value="-0.007" spread="0.0484"/>
                    <measurement group_id="O4" value="0.016" spread="0.0240"/>
                    <measurement group_id="O5" value="-0.018" spread="0.0338"/>
                    <measurement group_id="O6" value="-0.003" spread="0.0585"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="0.0492"/>
                    <measurement group_id="O2" value="-0.043" spread="0.0686"/>
                    <measurement group_id="O3" value="0.000" spread="0.0551"/>
                    <measurement group_id="O4" value="0.011" spread="0.0448"/>
                    <measurement group_id="O5" value="-0.011" spread="0.0501"/>
                    <measurement group_id="O6" value="0.000" spread="0.0456"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.017" spread="0.0525"/>
                    <measurement group_id="O2" value="-0.030" spread="0.0576"/>
                    <measurement group_id="O3" value="0.000" spread="0.0456"/>
                    <measurement group_id="O4" value="0.000" spread="0.0566"/>
                    <measurement group_id="O5" value="-0.036" spread="0.0773"/>
                    <measurement group_id="O6" value="0.000" spread="0.0551"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.008" spread="0.0422"/>
                    <measurement group_id="O2" value="-0.023" spread="0.0585"/>
                    <measurement group_id="O3" value="-0.017" spread="0.0686"/>
                    <measurement group_id="O4" value="0.000" spread="0.0424"/>
                    <measurement group_id="O5" value="-0.047" spread="0.0557"/>
                    <measurement group_id="O6" value="-0.003" spread="0.0320"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0542"/>
                    <measurement group_id="O2" value="-0.057" spread="0.0320"/>
                    <measurement group_id="O3" value="-0.017" spread="0.0463"/>
                    <measurement group_id="O4" value="0.000" spread="0.0469"/>
                    <measurement group_id="O5" value="-0.036" spread="0.0477"/>
                    <measurement group_id="O6" value="-0.027" spread="0.0432"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.0245"/>
                    <measurement group_id="O2" value="-0.023" spread="0.0497"/>
                    <measurement group_id="O3" value="0.017" spread="0.0480"/>
                    <measurement group_id="O6" value="-0.027" spread="0.0301"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="0.0532"/>
                    <measurement group_id="O4" value="0.004" spread="0.0133"/>
                    <measurement group_id="O5" value="-0.013" spread="0.0447"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.030" spread="0.0424"/>
                    <measurement group_id="O6" value="-0.030" spread="0.0329"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Day 2,n=12,6,5,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.83" spread="1.135"/>
                    <measurement group_id="O2" value="-0.17" spread="0.408"/>
                    <measurement group_id="O3" value="0.20" spread="1.304"/>
                    <measurement group_id="O4" value="-0.67" spread="0.791"/>
                    <measurement group_id="O5" value="-0.28" spread="0.833"/>
                    <measurement group_id="O6" value="-1.25" spread="1.084"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.79" spread="1.373"/>
                    <measurement group_id="O2" value="0.00" spread="0.316"/>
                    <measurement group_id="O3" value="-0.17" spread="0.931"/>
                    <measurement group_id="O4" value="-0.72" spread="0.833"/>
                    <measurement group_id="O5" value="-0.28" spread="0.755"/>
                    <measurement group_id="O6" value="-1.17" spread="1.402"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.75" spread="1.357"/>
                    <measurement group_id="O2" value="-0.25" spread="0.274"/>
                    <measurement group_id="O3" value="-0.33" spread="1.169"/>
                    <measurement group_id="O4" value="-0.61" spread="0.928"/>
                    <measurement group_id="O5" value="0.00" spread="0.707"/>
                    <measurement group_id="O6" value="-0.50" spread="1.673"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.71" spread="1.339"/>
                    <measurement group_id="O2" value="-0.33" spread="0.816"/>
                    <measurement group_id="O3" value="0.67" spread="1.169"/>
                    <measurement group_id="O4" value="-0.61" spread="0.961"/>
                    <measurement group_id="O5" value="-0.17" spread="0.968"/>
                    <measurement group_id="O6" value="-0.67" spread="1.602"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 1,n=11,6,6,9,9,5</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="11"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="5"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.45" spread="1.150"/>
                    <measurement group_id="O2" value="-0.50" spread="1.183"/>
                    <measurement group_id="O3" value="0.50" spread="1.581"/>
                    <measurement group_id="O4" value="-0.44" spread="1.014"/>
                    <measurement group_id="O5" value="0.11" spread="0.782"/>
                    <measurement group_id="O6" value="-1.10" spread="1.084"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.33" spread="1.267"/>
                    <measurement group_id="O2" value="-0.75" spread="1.037"/>
                    <measurement group_id="O3" value="0.33" spread="1.780"/>
                    <measurement group_id="O4" value="0.06" spread="0.726"/>
                    <measurement group_id="O5" value="-0.17" spread="0.612"/>
                    <measurement group_id="O6" value="-0.33" spread="1.080"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.25" spread="1.098"/>
                    <measurement group_id="O2" value="-0.75" spread="0.524"/>
                    <measurement group_id="O3" value="0.75" spread="0.822"/>
                    <measurement group_id="O4" value="0.22" spread="0.972"/>
                    <measurement group_id="O5" value="0.17" spread="1.225"/>
                    <measurement group_id="O6" value="-0.08" spread="1.114"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.75" spread="0.989"/>
                    <measurement group_id="O2" value="-0.17" spread="1.033"/>
                    <measurement group_id="O3" value="1.17" spread="1.252"/>
                    <measurement group_id="O4" value="0.06" spread="1.074"/>
                    <measurement group_id="O5" value="0.28" spread="1.093"/>
                    <measurement group_id="O6" value="-0.58" spread="1.158"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.75" spread="1.323"/>
                    <measurement group_id="O2" value="0.17" spread="0.983"/>
                    <measurement group_id="O3" value="0.17" spread="0.816"/>
                    <measurement group_id="O4" value="-0.06" spread="0.527"/>
                    <measurement group_id="O5" value="0.06" spread="0.682"/>
                    <measurement group_id="O6" value="0.25" spread="1.037"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.08" spread="1.505"/>
                    <measurement group_id="O2" value="0.50" spread="1.414"/>
                    <measurement group_id="O3" value="0.58" spread="1.068"/>
                    <measurement group_id="O4" value="0.39" spread="1.516"/>
                    <measurement group_id="O5" value="0.00" spread="0.866"/>
                    <measurement group_id="O6" value="-0.33" spread="0.983"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 24,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.79" spread="1.389"/>
                    <measurement group_id="O2" value="-0.17" spread="0.876"/>
                    <measurement group_id="O3" value="1.42" spread="1.594"/>
                    <measurement group_id="O4" value="0.11" spread="1.453"/>
                    <measurement group_id="O5" value="0.33" spread="1.146"/>
                    <measurement group_id="O6" value="0.17" spread="0.683"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.38" spread="1.069"/>
                    <measurement group_id="O2" value="-0.33" spread="0.983"/>
                    <measurement group_id="O3" value="0.83" spread="1.366"/>
                    <measurement group_id="O4" value="-0.17" spread="1.000"/>
                    <measurement group_id="O5" value="0.22" spread="0.755"/>
                    <measurement group_id="O6" value="0.08" spread="1.068"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.00" spread="0.949"/>
                    <measurement group_id="O2" value="-0.33" spread="0.683"/>
                    <measurement group_id="O3" value="0.75" spread="1.405"/>
                    <measurement group_id="O6" value="-0.08" spread="0.801"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.58" spread="1.855"/>
                    <measurement group_id="O4" value="-0.72" spread="1.034"/>
                    <measurement group_id="O5" value="0.28" spread="1.228"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>BUN, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.00" spread="0.000"/>
                    <measurement group_id="O6" value="-0.42" spread="1.201"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Presence of Ketones, Glucose, Occult Blood, and Protein</title>
        <description>Urine samples were collected to analyze presence of ketones, occult blood, glucose, and protein in urine. In this dipstick test, the level of occult blood, glucose, ketones and urine protein in urine samples were recorded as negative, trace, 1+ and 2+ indicating proportional concentrations in urine. Only categories with abnormal significant values have been presented.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Presence of Ketones, Glucose, Occult Blood, and Protein</title>
          <description>Urine samples were collected to analyze presence of ketones, occult blood, glucose, and protein in urine. In this dipstick test, the level of occult blood, glucose, ketones and urine protein in urine samples were recorded as negative, trace, 1+ and 2+ indicating proportional concentrations in urine. Only categories with abnormal significant values have been presented.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Occult blood, Trace,Week 4,n=2,1,1,5,0,1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O6" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace,Day 2,n=1,2,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Day 4,n=0,0,1,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Day 5,n=2,0,0,2,1,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="1"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Week 1,n=2,1,1,3,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Week 2,n=1,0,0,3,1,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="1"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O4" value="1"/>
                    <measurement group_id="O5" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Week 4,n=2,1,1,5,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Week 18,n=2,1,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Week 24,n=1,1,0,4,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace, Week 26,n=0,0,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O4" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, Trace,Week 32,n=1,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Ketone, 1+, Week 40,n=0,0,0,0,0,1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O6" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Protein, 2+, Week 4,n=2,1,1,5,0,1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O6" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Protein, Trace, Week 8,n=1,0,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urine Protein, Trace, Week 18,n=2,1,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Urine Potential of Hydrogen (pH) Analysis by Dipstick Method</title>
        <description>Urinary pH measurement is a routine part of urinalysis. Urine pH is an acid-base measurement. pH is measured on a numeric scale ranging from 0 to 14; values on the scale refer to the degree of alkalinity or acidity. A pH of 7 is neutral. A pH less than 7 is acidic, and a pH greater than 7 is basic. Normal urine has a slightly acid pH (5.0 - 6.0).</description>
        <time_frame>Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Urine Potential of Hydrogen (pH) Analysis by Dipstick Method</title>
          <description>Urinary pH measurement is a routine part of urinalysis. Urine pH is an acid-base measurement. pH is measured on a numeric scale ranging from 0 to 14; values on the scale refer to the degree of alkalinity or acidity. A pH of 7 is neutral. A pH less than 7 is acidic, and a pH greater than 7 is basic. Normal urine has a slightly acid pH (5.0 - 6.0).</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>pH</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="3"/>
                <count group_id="O2" value="1"/>
                <count group_id="O3" value="1"/>
                <count group_id="O4" value="5"/>
                <count group_id="O5" value="1"/>
                <count group_id="O6" value="1"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Day 2,n=1,1,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O2" value="7.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="6.50" spread="1.414"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 3,n=3,0,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="3"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.00" spread="0.500"/>
                    <measurement group_id="O4" value="5.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 4,n=0,0,1,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O3" value="6.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Day 5,n=2,0,0,2,1,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="1"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.50" spread="0.707"/>
                    <measurement group_id="O4" value="5.75" spread="1.061"/>
                    <measurement group_id="O5" value="5.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1,n=2,1,1,3,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.50" spread="0.000"/>
                    <measurement group_id="O2" value="7.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O3" value="6.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.50" spread="0.500"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2,n=1,0,0,4,1,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="1"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.63" spread="0.479"/>
                    <measurement group_id="O5" value="8.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4,n=3,1,1,5,0,1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="3"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.50" spread="0.866"/>
                    <measurement group_id="O2" value="8.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O3" value="5.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="6.00" spread="0.707"/>
                    <measurement group_id="O6" value="5.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8,n=1,0,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.50" spread="0.000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12,n=0,1,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="6.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 18,n=3,1,0,1,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="3"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.67" spread="0.577"/>
                    <measurement group_id="O2" value="7.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24,n=1,1,0,4,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.00" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O2" value="6.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                    <measurement group_id="O4" value="5.38" spread="0.479"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 26,n=0,0,0,2,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O4" value="5.50" spread="0.000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32,n=1,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.50" spread="NA">NA indicates that standard deviation could not be calculated for a single data point.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36,n=0,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
            </class>
            <class>
              <title>Week 40,n=0,0,0,0,0,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Absolute Values of Complement (C)3 and C4</title>
        <description>Blood samples were collected at indicated timepoints for analysis for complement (C3 and C4). Baseline was defined as latest pre-dose assessment with a non-missing value.</description>
        <time_frame>Baseline and at Days 2, 3, 4 and 5; Weeks 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40</time_frame>
        <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
          </group>
          <group group_id="O2">
            <title>GSK3511294 2mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
          </group>
          <group group_id="O3">
            <title>GSK3511294 10mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
          </group>
          <group group_id="O4">
            <title>GSK3511294 30mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
          </group>
          <group group_id="O5">
            <title>GSK3511294 100mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
          </group>
          <group group_id="O6">
            <title>GSK3511294 300mg</title>
            <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
          </group>
        </group_list>
        <measure>
          <title>Absolute Values of Complement (C)3 and C4</title>
          <description>Blood samples were collected at indicated timepoints for analysis for complement (C3 and C4). Baseline was defined as latest pre-dose assessment with a non-missing value.</description>
          <population>Safety Population. Only those participants with planned assessments at that particular time point has been presented (represented by n= X in the category titles).</population>
          <units>Grams per liter</units>
          <param>Geometric Mean</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="12"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="6"/>
                <count group_id="O4" value="9"/>
                <count group_id="O5" value="9"/>
                <count group_id="O6" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>C3, Baseline,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.149" lower_limit="1.061" upper_limit="1.243"/>
                    <measurement group_id="O2" value="1.182" lower_limit="0.995" upper_limit="1.404"/>
                    <measurement group_id="O3" value="1.086" lower_limit="0.941" upper_limit="1.254"/>
                    <measurement group_id="O4" value="1.074" lower_limit="0.982" upper_limit="1.175"/>
                    <measurement group_id="O5" value="1.137" lower_limit="1.013" upper_limit="1.277"/>
                    <measurement group_id="O6" value="1.254" lower_limit="1.122" upper_limit="1.402"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.13" lower_limit="1.042" upper_limit="1.225"/>
                    <measurement group_id="O2" value="1.27" lower_limit="1.051" upper_limit="1.535"/>
                    <measurement group_id="O3" value="1.16" lower_limit="0.940" upper_limit="1.433"/>
                    <measurement group_id="O4" value="1.114" lower_limit="1.018" upper_limit="1.219"/>
                    <measurement group_id="O5" value="1.188" lower_limit="1.053" upper_limit="1.341"/>
                    <measurement group_id="O6" value="1.286" lower_limit="1.182" upper_limit="1.400"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.187" lower_limit="1.063" upper_limit="1.325"/>
                    <measurement group_id="O2" value="1.244" lower_limit="1.029" upper_limit="1.503"/>
                    <measurement group_id="O3" value="1.236" lower_limit="1.011" upper_limit="1.511"/>
                    <measurement group_id="O4" value="1.142" lower_limit="1.037" upper_limit="1.258"/>
                    <measurement group_id="O5" value="1.157" lower_limit="1.038" upper_limit="1.290"/>
                    <measurement group_id="O6" value="1.322" lower_limit="1.197" upper_limit="1.460"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.17" lower_limit="1.051" upper_limit="1.302"/>
                    <measurement group_id="O2" value="1.284" lower_limit="1.023" upper_limit="1.611"/>
                    <measurement group_id="O3" value="1.181" lower_limit="1.016" upper_limit="1.374"/>
                    <measurement group_id="O4" value="1.144" lower_limit="1.051" upper_limit="1.245"/>
                    <measurement group_id="O5" value="1.165" lower_limit="1.038" upper_limit="1.307"/>
                    <measurement group_id="O6" value="1.316" lower_limit="1.189" upper_limit="1.458"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.136" lower_limit="1.011" upper_limit="1.277"/>
                    <measurement group_id="O2" value="1.122" lower_limit="0.993" upper_limit="1.268"/>
                    <measurement group_id="O3" value="1.092" lower_limit="0.909" upper_limit="1.311"/>
                    <measurement group_id="O4" value="1.113" lower_limit="1.011" upper_limit="1.226"/>
                    <measurement group_id="O5" value="1.165" lower_limit="1.026" upper_limit="1.323"/>
                    <measurement group_id="O6" value="1.305" lower_limit="1.159" upper_limit="1.469"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.136" lower_limit="1.062" upper_limit="1.215"/>
                    <measurement group_id="O2" value="1.147" lower_limit="0.986" upper_limit="1.333"/>
                    <measurement group_id="O3" value="1.02" lower_limit="0.841" upper_limit="1.238"/>
                    <measurement group_id="O4" value="1.139" lower_limit="1.045" upper_limit="1.241"/>
                    <measurement group_id="O5" value="1.174" lower_limit="1.039" upper_limit="1.327"/>
                    <measurement group_id="O6" value="1.28" lower_limit="1.136" upper_limit="1.442"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.114" lower_limit="1.043" upper_limit="1.191"/>
                    <measurement group_id="O2" value="1.05" lower_limit="0.873" upper_limit="1.262"/>
                    <measurement group_id="O3" value="1.111" lower_limit="0.900" upper_limit="1.370"/>
                    <measurement group_id="O4" value="1.07" lower_limit="0.957" upper_limit="1.197"/>
                    <measurement group_id="O5" value="1.148" lower_limit="1.019" upper_limit="1.293"/>
                    <measurement group_id="O6" value="1.22" lower_limit="1.085" upper_limit="1.372"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.224" lower_limit="1.150" upper_limit="1.303"/>
                    <measurement group_id="O2" value="1.226" lower_limit="1.115" upper_limit="1.347"/>
                    <measurement group_id="O3" value="1.097" lower_limit="0.875" upper_limit="1.376"/>
                    <measurement group_id="O4" value="1.117" lower_limit="0.993" upper_limit="1.257"/>
                    <measurement group_id="O5" value="1.167" lower_limit="1.085" upper_limit="1.254"/>
                    <measurement group_id="O6" value="1.34" lower_limit="1.191" upper_limit="1.506"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.117" lower_limit="1.011" upper_limit="1.234"/>
                    <measurement group_id="O2" value="1.033" lower_limit="0.935" upper_limit="1.141"/>
                    <measurement group_id="O3" value="1.124" lower_limit="0.947" upper_limit="1.334"/>
                    <measurement group_id="O4" value="1.147" lower_limit="1.050" upper_limit="1.254"/>
                    <measurement group_id="O5" value="1.211" lower_limit="1.065" upper_limit="1.377"/>
                    <measurement group_id="O6" value="1.28" lower_limit="1.117" upper_limit="1.465"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.173" lower_limit="1.065" upper_limit="1.291"/>
                    <measurement group_id="O2" value="1.215" lower_limit="0.984" upper_limit="1.500"/>
                    <measurement group_id="O3" value="1.124" lower_limit="0.922" upper_limit="1.370"/>
                    <measurement group_id="O4" value="1.184" lower_limit="1.045" upper_limit="1.342"/>
                    <measurement group_id="O5" value="1.231" lower_limit="1.119" upper_limit="1.353"/>
                    <measurement group_id="O6" value="1.283" lower_limit="1.158" upper_limit="1.422"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 24,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.15" lower_limit="1.067" upper_limit="1.238"/>
                    <measurement group_id="O2" value="1.136" lower_limit="1.031" upper_limit="1.252"/>
                    <measurement group_id="O3" value="1.171" lower_limit="1.029" upper_limit="1.332"/>
                    <measurement group_id="O4" value="1.157" lower_limit="1.019" upper_limit="1.312"/>
                    <measurement group_id="O5" value="1.243" lower_limit="1.107" upper_limit="1.395"/>
                    <measurement group_id="O6" value="1.222" lower_limit="1.100" upper_limit="1.356"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.204" lower_limit="1.106" upper_limit="1.311"/>
                    <measurement group_id="O2" value="0.927" lower_limit="0.450" upper_limit="1.910"/>
                    <measurement group_id="O3" value="1.142" lower_limit="0.963" upper_limit="1.355"/>
                    <measurement group_id="O4" value="1.156" lower_limit="1.070" upper_limit="1.249"/>
                    <measurement group_id="O5" value="1.222" lower_limit="1.081" upper_limit="1.381"/>
                    <measurement group_id="O6" value="1.298" lower_limit="1.123" upper_limit="1.501"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.173" lower_limit="0.985" upper_limit="1.398"/>
                    <measurement group_id="O2" value="1.243" lower_limit="1.137" upper_limit="1.358"/>
                    <measurement group_id="O3" value="1.231" lower_limit="1.016" upper_limit="1.491"/>
                    <measurement group_id="O6" value="1.204" lower_limit="1.116" upper_limit="1.299"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.243" lower_limit="1.107" upper_limit="1.397"/>
                    <measurement group_id="O4" value="1.188" lower_limit="1.085" upper_limit="1.301"/>
                    <measurement group_id="O5" value="1.236" lower_limit="1.106" upper_limit="1.382"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C3, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.181" lower_limit="NA" upper_limit="NA">NA indicates not available as 95% Confidence Interval (CI) was only available when at least 3 participants contribute to the statistics</measurement>
                    <measurement group_id="O6" value="1.231" lower_limit="1.069" upper_limit="1.417"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Baseline,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2576" lower_limit="0.2108" upper_limit="0.3147"/>
                    <measurement group_id="O2" value="0.2061" lower_limit="0.1653" upper_limit="0.2570"/>
                    <measurement group_id="O3" value="0.1919" lower_limit="0.1337" upper_limit="0.2755"/>
                    <measurement group_id="O4" value="0.2144" lower_limit="0.1727" upper_limit="0.2663"/>
                    <measurement group_id="O5" value="0.1939" lower_limit="0.1496" upper_limit="0.2512"/>
                    <measurement group_id="O6" value="0.215" lower_limit="0.1859" upper_limit="0.2488"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Day 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2525" lower_limit="0.2037" upper_limit="0.3130"/>
                    <measurement group_id="O2" value="0.2161" lower_limit="0.1832" upper_limit="0.2549"/>
                    <measurement group_id="O3" value="0.2061" lower_limit="0.1469" upper_limit="0.2891"/>
                    <measurement group_id="O4" value="0.2133" lower_limit="0.1784" upper_limit="0.2549"/>
                    <measurement group_id="O5" value="0.203" lower_limit="0.1597" upper_limit="0.2581"/>
                    <measurement group_id="O6" value="0.22" lower_limit="0.1832" upper_limit="0.2643"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Day 3,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2647" lower_limit="0.2068" upper_limit="0.3389"/>
                    <measurement group_id="O2" value="0.2038" lower_limit="0.1685" upper_limit="0.2464"/>
                    <measurement group_id="O3" value="0.2212" lower_limit="0.1464" upper_limit="0.3342"/>
                    <measurement group_id="O4" value="0.2142" lower_limit="0.1759" upper_limit="0.2609"/>
                    <measurement group_id="O5" value="0.1962" lower_limit="0.1514" upper_limit="0.2544"/>
                    <measurement group_id="O6" value="0.223" lower_limit="0.1921" upper_limit="0.2589"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Day 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.253" lower_limit="0.2013" upper_limit="0.3179"/>
                    <measurement group_id="O2" value="0.2303" lower_limit="0.1918" upper_limit="0.2767"/>
                    <measurement group_id="O3" value="0.2006" lower_limit="0.1416" upper_limit="0.2842"/>
                    <measurement group_id="O4" value="0.2128" lower_limit="0.1766" upper_limit="0.2564"/>
                    <measurement group_id="O5" value="0.1935" lower_limit="0.1472" upper_limit="0.2543"/>
                    <measurement group_id="O6" value="0.2188" lower_limit="0.1867" upper_limit="0.2564"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Day 5,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2497" lower_limit="0.1929" upper_limit="0.3232"/>
                    <measurement group_id="O2" value="0.1892" lower_limit="0.1572" upper_limit="0.2277"/>
                    <measurement group_id="O3" value="0.1866" lower_limit="0.1327" upper_limit="0.2680"/>
                    <measurement group_id="O4" value="0.2073" lower_limit="0.1685" upper_limit="0.2551"/>
                    <measurement group_id="O5" value="0.1943" lower_limit="0.1492" upper_limit="0.2531"/>
                    <measurement group_id="O6" value="0.2163" lower_limit="0.1869" upper_limit="0.2503"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 2,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2555" lower_limit="0.2028" upper_limit="0.3220"/>
                    <measurement group_id="O2" value="0.2108" lower_limit="0.1768" upper_limit="0.2514"/>
                    <measurement group_id="O3" value="0.1781" lower_limit="0.1172" upper_limit="0.2706"/>
                    <measurement group_id="O4" value="0.221" lower_limit="0.1813" upper_limit="0.2695"/>
                    <measurement group_id="O5" value="0.2018" lower_limit="0.1497" upper_limit="0.2720"/>
                    <measurement group_id="O6" value="0.2169" lower_limit="0.1765" upper_limit="0.2664"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 4,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2602" lower_limit="0.2078" upper_limit="0.3258"/>
                    <measurement group_id="O2" value="0.1928" lower_limit="0.1623" upper_limit="0.2290"/>
                    <measurement group_id="O3" value="0.189" lower_limit="0.1292" upper_limit="0.2766"/>
                    <measurement group_id="O4" value="0.2063" lower_limit="0.1636" upper_limit="0.2602"/>
                    <measurement group_id="O5" value="0.1872" lower_limit="0.1419" upper_limit="0.2468"/>
                    <measurement group_id="O6" value="0.1929" lower_limit="0.1733" upper_limit="0.2146"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 8,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2738" lower_limit="0.2186" upper_limit="0.3431"/>
                    <measurement group_id="O2" value="0.2547" lower_limit="0.2010" upper_limit="0.3226"/>
                    <measurement group_id="O3" value="0.2045" lower_limit="0.1315" upper_limit="0.3180"/>
                    <measurement group_id="O4" value="0.2009" lower_limit="0.1654" upper_limit="0.2441"/>
                    <measurement group_id="O5" value="0.1901" lower_limit="0.1542" upper_limit="0.2343"/>
                    <measurement group_id="O6" value="0.2231" lower_limit="0.1778" upper_limit="0.2800"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 12,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2413" lower_limit="0.1901" upper_limit="0.3063"/>
                    <measurement group_id="O2" value="0.1862" lower_limit="0.1567" upper_limit="0.2213"/>
                    <measurement group_id="O3" value="0.2034" lower_limit="0.1307" upper_limit="0.3167"/>
                    <measurement group_id="O4" value="0.2114" lower_limit="0.1723" upper_limit="0.2594"/>
                    <measurement group_id="O5" value="0.196" lower_limit="0.1494" upper_limit="0.2572"/>
                    <measurement group_id="O6" value="0.2074" lower_limit="0.1792" upper_limit="0.2400"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 18,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.261" lower_limit="0.1992" upper_limit="0.3420"/>
                    <measurement group_id="O2" value="0.2266" lower_limit="0.1873" upper_limit="0.2742"/>
                    <measurement group_id="O3" value="0.2025" lower_limit="0.1322" upper_limit="0.3102"/>
                    <measurement group_id="O4" value="0.226" lower_limit="0.1920" upper_limit="0.2660"/>
                    <measurement group_id="O5" value="0.1678" lower_limit="0.1255" upper_limit="0.2245"/>
                    <measurement group_id="O6" value="0.216" lower_limit="0.1740" upper_limit="0.2681"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 24,n=12,6,6,8,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="8"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2474" lower_limit="0.1894" upper_limit="0.3232"/>
                    <measurement group_id="O2" value="0.2244" lower_limit="0.1742" upper_limit="0.2890"/>
                    <measurement group_id="O3" value="0.197" lower_limit="0.1324" upper_limit="0.2932"/>
                    <measurement group_id="O4" value="0.206" lower_limit="0.1801" upper_limit="0.2357"/>
                    <measurement group_id="O5" value="0.1909" lower_limit="0.1500" upper_limit="0.2430"/>
                    <measurement group_id="O6" value="0.2114" lower_limit="0.1682" upper_limit="0.2658"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 26,n=12,6,6,9,9,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="12"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2517" lower_limit="0.1926" upper_limit="0.3291"/>
                    <measurement group_id="O2" value="0.202" lower_limit="0.1319" upper_limit="0.3095"/>
                    <measurement group_id="O3" value="0.1939" lower_limit="0.1291" upper_limit="0.2912"/>
                    <measurement group_id="O4" value="0.2115" lower_limit="0.1704" upper_limit="0.2627"/>
                    <measurement group_id="O5" value="0.163" lower_limit="0.1250" upper_limit="0.2126"/>
                    <measurement group_id="O6" value="0.226" lower_limit="0.1887" upper_limit="0.2627"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 32,n=6,6,6,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="6"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2772" lower_limit="0.1617" upper_limit="0.4754"/>
                    <measurement group_id="O2" value="0.2401" lower_limit="0.2003" upper_limit="0.2877"/>
                    <measurement group_id="O3" value="0.2007" lower_limit="0.1297" upper_limit="0.3105"/>
                    <measurement group_id="O6" value="0.2051" lower_limit="0.1808" upper_limit="0.2326"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 36,n=6,0,0,9,9,0</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="6"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="9"/>
                    <count group_id="O5" value="9"/>
                    <count group_id="O6" value="0"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2844" lower_limit="0.2110" upper_limit="0.3834"/>
                    <measurement group_id="O4" value="0.2025" lower_limit="0.1637" upper_limit="0.2504"/>
                    <measurement group_id="O5" value="0.206" lower_limit="0.1626" upper_limit="0.2611"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>C4, Week 40,n=2,0,0,0,0,6</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="0"/>
                    <count group_id="O3" value="0"/>
                    <count group_id="O4" value="0"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="6"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1699" lower_limit="NA" upper_limit="NA">NA indicates not available as 95% Confidence Interval (CI) was only available when at least 3 participants contribute to the statistics</measurement>
                    <measurement group_id="O6" value="0.2134" lower_limit="0.1766" upper_limit="0.2580"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
    </outcome_list>

    <reported_events>
      <time_frame>Non-serious AEs and SAEs were collected from the start of the study treatment (Day 1) up to Week 32 for GSK3511294 2 mg and 10 mg, up to Week 36 for GSK3511294 30 mg and GSK3511294 100 mg and up to Week 40 for GSK3511294 300 mg; and up to 40 weeks for placebo.</time_frame>
      <desc>Non-SAEs and SAEs were reported for the Safety Population. Within each cohort participants were assigned to active or placebo in a 3:1 ratio. A pooled placebo group was to be used as comparison group. An identical proportion of participants in pooled placebo group had same total duration of study as participants in each of the active dose groups</desc>
      <group_list>
        <group group_id="E1">
          <title>Placebo</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 matching placebo on Day 1</description>
        </group>
        <group group_id="E2">
          <title>GSK3511294 2mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 2 milligram (mg) on Day 1</description>
        </group>
        <group group_id="E3">
          <title>GSK3511294 10mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 10 mg on Day 1</description>
        </group>
        <group group_id="E4">
          <title>GSK3511294 30mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 30 mg on Day 1</description>
        </group>
        <group group_id="E5">
          <title>GSK3511294 100mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 100 mg on Day 1</description>
        </group>
        <group group_id="E6">
          <title>GSK3511294 300mg</title>
          <description>Participants were administered a single subcutaneous dose of GSK3511294 300 mg on Day 1</description>
        </group>
      </group_list>
      <serious_events>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, all-cause mortality</sub_title>
                <counts group_id="E1" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Total, serious adverse events</sub_title>
                <counts group_id="E1" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </serious_events>
      <other_events>
        <frequency_threshold>5</frequency_threshold>
        <default_vocab>MedDRA 22.0</default_vocab>
        <default_assessment>Systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, other adverse events</sub_title>
                <counts group_id="E1" subjects_affected="11" subjects_at_risk="12"/>
                <counts group_id="E2" subjects_affected="2" subjects_at_risk="6"/>
                <counts group_id="E3" subjects_affected="6" subjects_at_risk="6"/>
                <counts group_id="E4" subjects_affected="8" subjects_at_risk="9"/>
                <counts group_id="E5" subjects_affected="9" subjects_at_risk="9"/>
                <counts group_id="E6" subjects_affected="4" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Eye disorders</title>
            <event_list>
              <event>
                <sub_title>Dry eye</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Gastrointestinal disorders</title>
            <event_list>
              <event>
                <sub_title>Diarrhoea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Dyspepsia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="2" subjects_affected="2" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Abdominal discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Dental pulp disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Food poisoning</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Mouth ulceration</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Tongue discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Toothache</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>General disorders</title>
            <event_list>
              <event>
                <sub_title>Medical device site reaction</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Injection site haematoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Chest discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Fatigue</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Hernia pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Injection site swelling</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Immune system disorders</title>
            <event_list>
              <event>
                <sub_title>Seasonal allergy</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="12"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E3" events="3" subjects_affected="2" subjects_at_risk="6"/>
                <counts group_id="E4" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="4" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Allergy to animal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Nasopharyngitis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="12"/>
                <counts group_id="E2" events="4" subjects_affected="2" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="3" subjects_affected="3" subjects_at_risk="9"/>
                <counts group_id="E5" events="5" subjects_affected="5" subjects_at_risk="9"/>
                <counts group_id="E6" events="2" subjects_affected="2" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Rhinitis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Gastroenteritis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Gastrointestinal infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Otitis media acute</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Respiratory tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Root canal infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Viral diarrhoea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Viral upper respiratory tract infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Injury, poisoning and procedural complications</title>
            <event_list>
              <event>
                <sub_title>Arthropod sting</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Contusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Rib fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="2" subjects_affected="2" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Back injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Fall</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Hand fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Ligament rupture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Limb injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Muscle strain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Post-traumatic pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Skin abrasion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Soft tissue injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Splinter</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Tendon injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Investigations</title>
            <event_list>
              <event>
                <sub_title>Peak expiratory flow rate decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="3" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="4" subjects_affected="1" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Metabolism and nutrition disorders</title>
            <event_list>
              <event>
                <sub_title>Vitamin B12 deficiency</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Back pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Musculoskeletal chest pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Neck pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Pain in extremity</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Neoplasms benign, malignant and unspecified (incl cysts and polyps)</title>
            <event_list>
              <event>
                <sub_title>Pyogenic granuloma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Nervous system disorders</title>
            <event_list>
              <event>
                <sub_title>Headache</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E3" events="2" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="4" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E5" events="4" subjects_affected="3" subjects_at_risk="9"/>
                <counts group_id="E6" events="2" subjects_affected="2" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Hypoaesthesia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Lethargy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Paraesthesia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Sciatica</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Psychiatric disorders</title>
            <event_list>
              <event>
                <sub_title>Anxiety</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Respiratory, thoracic and mediastinal disorders</title>
            <event_list>
              <event>
                <sub_title>Oropharyngeal pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Asthma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Cough</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Epistaxis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Nasal congestion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Nasal discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Rhinorrhoea</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Skin and subcutaneous tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Dry skin</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="2" subjects_affected="2" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Acne</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Papule</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
              <event>
                <sub_title>Rash</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Surgical and medical procedures</title>
            <event_list>
              <event>
                <sub_title>Dental care</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Vascular disorders</title>
            <event_list>
              <event>
                <sub_title>Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="12"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="9"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="9"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="6"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </other_events>
    </reported_events>

    <certain_agreements>
      <pi_employee>Principal Investigators are NOT employed by the organization sponsoring the study.</pi_employee>
      <restrictive_agreement>GSK agreements may vary with individual investigators, but will not prohibit any investigator from publishing. GSK supports the publication of results from all centers of a multi-center trial but requests that reports based on single-site data not precede the primary publication of the entire clinical trial.</restrictive_agreement>
    </certain_agreements>
    <point_of_contact>
      <name_or_title>GSK Response Center</name_or_title>
      <organization>GlaxoSmithKline</organization>
      <phone>8664357343 ext 1</phone>
      <email>GSKClinicalSupportHD@gsk.com</email>
    </point_of_contact>
  </clinical_results>
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03287310
org study id: 205722
secondary id: 2016-004256-30
nct id: NCT03287310
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
GSK3511294 is a humanized monoclonal antibody antagonist of Interleukin (IL)-5 which is known
      to block binding of IL-5 to the IL-5 receptor complex, causing a reduction in the circulating
      population of eosinophils. This is a single ascending dose FTIH study to investigate safety,
      tolerability, immunogenicity, pharmacokinetics (PK) and pharmacodynamics (PD) of GSK3511294,
      administered SC in subjects with mild to moderate asthma maintained on a low-medium daily
      dose of inhaled corticosteroids (ICS) or ICS/long acting beta-agonist (LABA), and short
      acting beta-agonist (SABA). The subjects will attend a pre-screen visit of up to 12 weeks
      before dosing for assessment of blood eosinophils. Eligible subjects with blood eosinophils
      >=200 cells per microliter (cells/µL) will undergo a screening period of up to 4 weeks. The
      subjects will then be randomized into 5 cohorts. In each cohort, the subjects will be
      randomized to receive a single dose of GSK3511294 or placebo in a ratio of 3:1. The follow-up
      period will be up to 40 weeks post dose and will be dose-dependent. The scheduled maximum
      duration for each subject will be up to 44 weeks including up to 28 days of screening.
allocation: Randomized
intervention model: Parallel Assignment
intervention model description: This is a multi-center, double-blind study in which subjects will be allocated to five cohorts. The subjects in each cohort will be randomized to receive GSK3511294 and placebo in a ratio of 3:1. In each cohort, dosing will be staggered: one subject will receive GSK3511294 and one subject will receive placebo at least 72 hours before the remaining subjects in that cohort are dosed. The remaining subjects will be dosed if the review of all safety data up to 72 hours after dosing of the first two subjects in each cohort is satisfactory.
primary purpose: Treatment
masking: Double (Participant, Investigator)
measure: Number of Participants With Adverse Events (AEs) and Serious AEs (SAE)
time frame: Up to Week 40
description: An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of a study intervention, whether or not considered related to the study intervention. An SAE is defined as any untoward medical occurrence that, at any dose: results in death; is life-threatening; requires inpatient hospitalization or prolongation of existing hospitalization; results in persistent disability/incapacity; is a congenital anomaly/birth defect; other important medical events that may jeopardize the participant or may require medical or surgical intervention to prevent one of the other outcomes listed before; is associated with liver injury and impaired liver function.
measure: Number of Participants With Adverse Events of Special Interest (AESI)
time frame: Up to Week 40
description: AESIs were defined as Hypersensitivity (narrow) and Injection site reactions like hematoma and swelling.
measure: Change From Baseline in Neutrophil, Lymphocyte, Monocyte, Eosinophil, Basophil and Platelet Count
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of hematology parameters like platelet count, neutrophils, lymphocytes, monocytes, eosinophils and basophils. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Red Blood Cell Count (RBC)
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of hematology parameters like RBC count. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Mean Corpuscle Volume (MCV)
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of hematology parameters like MCV. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Mean Corpuscle Hemoglobin (MCH)
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of hematology parameters like MCH. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Hemoglobin
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of hematology parameters like hemoglobin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Hematocrit
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of hematology parameters like hematocrit. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Clinical Chemistry Parameter: High Sensitivity C-reactive Protein (hsCRP)
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of clinical parameters like hsCRP. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Clinical Chemistry Parameter of Total Protein and Albumin
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of clinical parameters like total protein and albumin. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Clinical Chemistry Parameters Like Total Bilirubin, Direct Bilirubin and Creatinine
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of clinical parameters like total bilirubin, direct bilirubin and creatinine. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Urine Specific Gravity Analysis by Dipstick Method
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Urinary specific gravity measurement is a routine part of urinalysis. Urine specific gravity is a measure of the concentration of solutes in the urine and provides information on the kidney's ability to concentrate urine. The concentration of the excreted molecules determines the urine's specific gravity.
measure: Change From Baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP)
time frame: Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: SBP and DBP were assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Temperature
time frame: Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Temperature was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Heart Rate
time frame: Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Heart rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Respiration Rate
time frame: Baseline and at 2 and 8 hours at Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Respiration rate was assessed in a supine position after 5 minutes of rest. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Heart Rate: Electrocardiogram (ECG)
time frame: Baseline and at 2 and 8 hours on Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: 12-lead ECG were performed in a supine position using an automated ECG machine that calculated the heart rate and measured PR, QRS, QT and corrected QT (QTc) intervals. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in PR Interval, QRS Interval, QT Interval and QT Interval Corrected by Fridericia's Formula (QTcF) Interval
time frame: Baseline and at 2 and 8 hours on Day 1; Days 2, 3, 4 and 5; Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: 12-lead ECG were performed in a supine position using an automated ECG machine that calculated PR interval, QRS interval, QT interval and QTcF interval. ECG measurements were performed in triplicate. When multiple ECGs were performed at the same planned timepoint, the average value of each parameter was used. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Clinical Chemistry Parameters Like Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), and Aspartate Aminotransferase (AST)
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of clinical parameters like ALP, AST and ALT. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Change From Baseline in Clinical Chemistry Parameter Like Glucose, Calcium, Potassium, Sodium, Blood Urea Nitrogen (BUN), and Magnesium
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated time-points for analysis of clinical parameters like glucose, calcium, potassium, sodium, BUN, and magnesium. Baseline was defined as latest pre-dose assessment with a non-missing value. Change from Baseline was defined as post-dose visit value minus Baseline value.
measure: Number of Participants With Presence of Ketones, Glucose, Occult Blood, and Protein
time frame: Baseline and at Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Urine samples were collected to analyze presence of ketones, occult blood, glucose, and protein in urine. In this dipstick test, the level of occult blood, glucose, ketones and urine protein in urine samples were recorded as negative, trace, 1+ and 2+ indicating proportional concentrations in urine. Only categories with abnormal significant values have been presented.
measure: Urine Potential of Hydrogen (pH) Analysis by Dipstick Method
time frame: Days 2, 3, 4 and 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Urinary pH measurement is a routine part of urinalysis. Urine pH is an acid-base measurement. pH is measured on a numeric scale ranging from 0 to 14; values on the scale refer to the degree of alkalinity or acidity. A pH of 7 is neutral. A pH less than 7 is acidic, and a pH greater than 7 is basic. Normal urine has a slightly acid pH (5.0 - 6.0).
measure: Absolute Values of Complement (C)3 and C4
time frame: Baseline and at Days 2, 3, 4 and 5; Weeks 2, 4, 8, 12, 18, 24, 26, 32, 36 and 40
description: Blood samples were collected at indicated timepoints for analysis for complement (C3 and C4). Baseline was defined as latest pre-dose assessment with a non-missing value.
measure: Area Under the Curve From Time Zero to Infinity (AUC[0-inf]) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis. Pharmacokinetic Population included participants in the Safety population for whom a pharmcokinetic sample was obtained and analyzed.
measure: AUC(0-inf) of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.
measure: AUC(0-inf) of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.
measure: Area Under the Curve From Time Zero to the Last Measurable Concentration (AUC[0-t]) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.
measure: AUC(0-t) of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters were calculated by standard non compartmental analysis.
measure: AUC(0-t) of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-t). Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Area Under the Concentration-time Curve From Time Zero to Week 4 (AUC[0-Week 4]) of GSK3511294
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, and 4 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 4). Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Area Under the Concentration-time Curve From Time Zero to Week 12 (AUC[0-Week 12]) of GSK3511294
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8 and 12 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 12). Pharmacokinetic parameters were calculated by standard non compartmental analysis.
measure: Area Under the Concentration-time Curve From Time Zero to Week 26 (AUC [0-Week 26]) of GSK3511294
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24 and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for AUC (0-Week 26). Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Percentage of AUC (0-inf) Obtained by Extrapolation (%AUCex) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: %AUCex of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: %AUCex of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for %AUCex. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Maximum Observed Concentration (Cmax) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Cmax of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Cmax of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Cmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Time of Occurrence of Cmax (Tmax) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Tmax of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Tmax of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Tmax. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Time of Last Quantifiable Concentration (Tlast) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Tlast of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Tlast of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Tlast. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Apparent Clearance Following Subcutaneous Dosing (CL/F) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: CL/F of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: CL/F of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for CL/F. CL/F was calculated as dose divided by AUC(0-inf). Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Apparent Volume of Distribution After Subcutaneous Administration (Vd/F) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by terminal elimination rate constant (lambda_z) *AUC(0-inf). Pharmacokinetic parameters were calculated by standard non compartmental analysis.
measure: Vd/F of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Vd/F of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for Vd/F. Vd/F was calculated as dose divided by [lambda_z *AUC(0-inf)]. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Terminal Phase Elimination Rate Constant (Lambda_z) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Lambda_z of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Lambda_z of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for lambda_z. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Terminal Phase Half-life (t1/2) of GSK3511294 2 mg and 10 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, and 26 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: T1/2 of GSK3511294 30 mg and 100 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26 and 36 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: T1/2 of GSK3511294 300 mg
time frame: Pre-dose, 2 and 8 hours on Day 1; Days 2,3,5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32 and 40 post-dose
description: Blood samples were collected from participants at indicated time points and analyzed for t1/2. Pharmacokinetic parameters was calculated by standard non compartmental analysis.
measure: Ratio to Baseline in Absolute Blood Eosinophil Count
time frame: Baseline, Days 2, 3, 4, 5, Weeks 1, 2, 4, 8, 12, 18, 24, 26, 32, 36, and 40
description: Blood samples were collected at indicated time-points. Analysis was performed using a mixed model repeated measures analysis (MMRM) model on log-transformed data with fixed categorical effects of treatment, planned timepoint and treatment-by-planned timepoint interaction and fixed continuous covariates of log Baseline blood eosinophil count and log Baseline blood eosinophil count-by-planned timepoint interaction. Baseline is defined as the latest predose non-missing blood eosinophil count. Ratio to Baseline is defined as post-dose visit value divided by Baseline value. Pharmacodynamic Population included participants in the 'Safety' population for whom a post-dose pharmacodynamic (ie blood eosinophil) sample was obtained and analyzed.
measure: Number of Participants With Anti-drug Antibody (ADA) Binding to GSK3511294
time frame: Up to Week 40
description: Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. The results were categorized as negative, transient positive (defined as a single confirmatory positive immunogenic response that does not occur at the final study assessment) and persistent positive (defined as a confirmatory positive immunogenic response for at least 2 consecutive assessments or a single result at the final study assessment).
measure: Titers of Binding ADA to GSK3511294
time frame: Up to Week 40
description: Serum samples were collected to determine the presence of anti-GSK3511294 binding antibodies using a validated bioanalytical method. Data for any time post-Baseline is reported. Titer was only measured when a positive result was found.
arm group label: Subjects receiving GSK3511294 in Cohort 1
arm group type: Experimental
description: Six subjects in Cohort 1 will receive a single SC dose of 2 mg GSK3511294.
arm group label: Subjects receiving placebo in Cohort 1
arm group type: Placebo Comparator
description: Two subjects in Cohort 1 will receive a single SC dose of placebo.
arm group label: Subjects receiving GSK3511294 in Cohort 2
arm group type: Experimental
description: Six subjects in Cohort 2 will receive a single SC dose of 10 mg GSK3511294.
arm group label: Subjects receiving placebo in Cohort 2
arm group type: Placebo Comparator
description: Two subjects in Cohort 2 will receive a single SC dose of placebo.
arm group label: Subjects receiving GSK3511294 in Cohort 3
arm group type: Experimental
description: Nine subjects in Cohort 3 will receive a single SC dose of 30 mg GSK3511294.
arm group label: Subjects receiving placebo in Cohort 3
arm group type: Placebo Comparator
description: Three subjects in Cohort 3 will receive a single SC dose of placebo.
arm group label: Subjects receiving GSK3511294 in Cohort 4
arm group type: Experimental
description: Nine subjects in Cohort 4 will receive a single SC dose of 100 mg GSK3511294.
arm group label: Subjects receiving placebo in Cohort 4
arm group type: Placebo Comparator
description: Three subjects in Cohort 4 will receive a single SC dose of placebo.
arm group label: Subjects receiving GSK3511294 in Cohort 5
arm group type: Experimental
description: Six subjects in Cohort 5 will receive a single SC dose of 300 mg GSK3511294.
arm group label: Subjects receiving placebo in Cohort 5
arm group type: Placebo Comparator
description: Two subjects in Cohort 5 will receive a single SC dose of placebo.
intervention type: Drug
intervention name: GSK3511294
description: GSK3511294 will be available as a clear or opalescent, colorless or yellow to brown solution for injection at unit dose strength of 150 milligrams per milliliter (mg/mL). GSK3511294 will be diluted in 0.9% weight by volume (w/v) sodium chloride to achieve the desired concentration for administration. GSK3511294 will be administered by SC injection.
arm group label: Subjects receiving GSK3511294 in Cohort 1
arm group label: Subjects receiving GSK3511294 in Cohort 2
arm group label: Subjects receiving GSK3511294 in Cohort 3
arm group label: Subjects receiving GSK3511294 in Cohort 4
arm group label: Subjects receiving GSK3511294 in Cohort 5
intervention type: Drug
intervention name: Placebo
description: Matching Placebo will consist of 0.9% w/v sodium chloride which will be administered by the SC route.
arm group label: Subjects receiving placebo in Cohort 1
arm group label: Subjects receiving placebo in Cohort 2
arm group label: Subjects receiving placebo in Cohort 3
arm group label: Subjects receiving placebo in Cohort 4
arm group label: Subjects receiving placebo in Cohort 5
intervention type: Drug
intervention name: Salbutamol/albuterol
description: Salbutamol/albuterol will be supplied to all subjects for use as rescue medication during the study.
arm group label: Subjects receiving GSK3511294 in Cohort 1
arm group label: Subjects receiving GSK3511294 in Cohort 2
arm group label: Subjects receiving GSK3511294 in Cohort 3
arm group label: Subjects receiving GSK3511294 in Cohort 4
arm group label: Subjects receiving GSK3511294 in Cohort 5
arm group label: Subjects receiving placebo in Cohort 1
arm group label: Subjects receiving placebo in Cohort 2
arm group label: Subjects receiving placebo in Cohort 3
arm group label: Subjects receiving placebo in Cohort 4
arm group label: Subjects receiving placebo in Cohort 5
criteria: 
gender: All
minimum age: 18 Years
maximum age: 65 Years
healthy volunteers: No
last name: GSK Clinical Trials
role: Study Director
affiliation: GlaxoSmithKline
facility: 
facility: 
facility: 
facility: 
facility: 
country: Germany
country: United Kingdom
responsible party type: Sponsor
mesh term: Asthma
mesh term: Albuterol
sharing ipd: Yes
ipd description: IPD for this study will be made available via the Clinical Study Data Request Site
ipd info type: Study Protocol
ipd info type: Statistical Analysis Plan (SAP)
ipd info type: Informed Consent Form (ICF)
ipd info type: Clinical Study Report (CSR)
ipd time frame: IPD will be made available within 6 months of publishing the results of the primary endpoints of the study
ipd access criteria: Access is provided after a research proposal is submitted and has received approval from the Independent Review Panel and after a Data Sharing Agreement is in place. Access is provided for an initial period of 12 months but an extension can be granted, when justified, for up to another 12 months.
ipd url: http://clinicalstudydatarequest.com
provided document: 
provided document: 
participant flow: 
baseline: 
outcome list: 
reported events: 
certain agreements: 
point of contact: 