<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03240003</url>
  </required_header>
  <id_info>
    <org_study_id>7527 (SAD)</org_study_id>
    <nct_id>NCT03240003</nct_id>
  </id_info>
  <brief_title>A Novel Computer-Based Therapy for Social Anxiety</brief_title>
  <official_title>A Novel Computer-Based Therapy for Social Anxiety</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>New York State Psychiatric Institute</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>New York State Psychiatric Institute</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      The present study is a double blind trial that seeks to examine the feasibility,&#xD;
      acceptability, efficacy, and mechanism of a recently developed eye-tracking-based therapy&#xD;
      (GC-MRT) in individuals with social anxiety disorder (SAD)&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      The present study is a double blind trial that seeks to examine the feasibility,&#xD;
      acceptability, efficacy, and mechanism of a recently developed eye-tracking-based therapy&#xD;
      (GC-MRT) in individuals with social anxiety disorder (SAD). The purpose of this study is to&#xD;
      assess whether a brief computer-based research treatment, provided in 30 minutes sessions&#xD;
      twice a week for 4 weeks, helps improve social anxiety symptoms, and by what mechanism. The&#xD;
      study will also assess the effect of research treatments on brain activity using a scan&#xD;
      called magnetic resonance imaging (MRI).&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Suspended</overall_status>
  <why_stopped>
    funding unavailable&#xD;
  </why_stopped>
  <start_date type="Actual">August 25, 2017</start_date>
  <completion_date type="Anticipated">December 1, 2025</completion_date>
  <primary_completion_date type="Anticipated">December 1, 2025</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Basic Science</primary_purpose>
    <masking>Triple (Participant, Investigator, Outcomes Assessor)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Liebowitz Social Anxiety Scale</measure>
    <time_frame>4 months</time_frame>
    <description>Total score of the Liebowitz Social Anxiety Scale</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Social Phobia Inventory (SPIN)</measure>
    <time_frame>4 months</time_frame>
    <description>The Social Phobia Inventory (abbreviated as SPIN) is a self-rated questionnaire that will be used to assess severity of social anxiety Disorder. 17 items related to social anxiety each rated on a score of 0 to 4, with a minimum total score of 0 (least social anxiety), and a maximum total score of 68 (most social anxiety).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Quality of Life Enjoyment &amp; Satisfaction Questionnaire</measure>
    <time_frame>4 months</time_frame>
    <description>Quality of Life Enjoyment &amp; Satisfaction Questionnaire (Q-LES-Q): self-rated assessment of quality of life. 16 items related to life quality, each rated on a score of 1 (very poor) to 5 (very good), with a minimum total score of 16, and a maximum total score of 80.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Revised Social Anhedonia Scale</measure>
    <time_frame>4 months</time_frame>
    <description>40-item self-rated social anhedonia scale. Items are comprised of statements that participants agree or disagree with, by answering &quot;yes&quot;(1), or &quot;no&quot;(0), with some items reverse-coded. The minimum score is 0 (least social anhedonia); maximum score is 40 (most social anhedonia).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Snaith Hamilton Pleasure Scale</measure>
    <time_frame>4 months</time_frame>
    <description>Snaith Hamilton Pleasure Scale (SHAPS). Fourteen-item self-rated anhedonia scale. Items were comprised of statements that participants rated as &quot;strongly disagree&quot; (1), &quot;disagree&quot; (2), &quot;agree&quot; (3), or &quot;strongly agree&quot; (4). The lowest possible score was 14, the highest possible score was 56 (greatest anhedonia)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Hamilton Rating Scale for Depression - 17 item version</measure>
    <time_frame>4 months</time_frame>
    <description>Hamilton Rating Scale for Depression -17 item version. This standard scale will be used to assess severity of depression, minimum score is 0 (least depression); maximum score is 50 (greatest depression).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Clinical Global Impression-Change Scale</measure>
    <time_frame>4 months</time_frame>
    <description>Clinical Global Impression-Change Scale: A quickly administered and widely used observer rating, with rating from 1 (very much improved) to 7 (very much worse). Responder category is defined by a score of 1 or 2.</description>
  </secondary_outcome>
  <number_of_arms>3</number_of_arms>
  <enrollment type="Anticipated">60</enrollment>
  <condition>Social Anxiety Disorder</condition>
  <arm_group>
    <arm_group_label>GC-MRT</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Group 1 will receive a 4-week (8-sessions) course of standard GC-MRT</description>
  </arm_group>
  <arm_group>
    <arm_group_label>non-GC-MRT</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>Group 2 will receive a 4-week (8-sessions) course of non-GC-MRT</description>
  </arm_group>
  <arm_group>
    <arm_group_label>GC-MRT-modified</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Group 3 will receive a 4-week (8-sessions) course of modified GC-MRT.</description>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>GC-MRT</intervention_name>
    <description>Group 1 will receive a 4-week (8-sessions) course of GC-MRT</description>
    <arm_group_label>GC-MRT</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>modified GC-MRT</intervention_name>
    <description>group 3 will receive a 4-week (8-sessions) course of GC-MRT, modified</description>
    <arm_group_label>GC-MRT-modified</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Non-GC-MRT</intervention_name>
    <description>Group 2 will receive a 4-week (8-sessions) course of non-GC-MRT</description>
    <arm_group_label>non-GC-MRT</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Males and females between the ages of 18 and 60&#xD;
&#xD;
          -  Current DSM-V primary diagnosis of SAD&#xD;
&#xD;
          -  Score of at least 50 on the Liebowitz Social Anxiety Scale (Self-rated version)&#xD;
&#xD;
          -  Fluent in English and willing and able to give informed written consent and&#xD;
             participate responsibly in the protocol&#xD;
&#xD;
          -  Normal or corrected-to-normal vision&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Present or past psychotic episode, psychotic disorder, schizophrenia, schizoaffective&#xD;
             disorder, or bipolar disorder&#xD;
&#xD;
          -  Current severe depression&#xD;
&#xD;
          -  Suicidal ideation or behavior&#xD;
&#xD;
          -  Current diagnosis of PTSD, obsessive-compulsive disorder, bipolar disorder, manic&#xD;
             episode or tic disorder&#xD;
&#xD;
          -  Current or past organic mental disorder, seizure disorder, epilepsy or brain injury&#xD;
&#xD;
          -  Current unstable or untreated medical illness&#xD;
&#xD;
          -  Severe alcohol use disorder, severe cannabis use disorder, and any severity of other&#xD;
             substance use disorder (except nicotine use disorders allowed)&#xD;
&#xD;
          -  Use of psychiatric medication in the past month other than a stable dose of selective&#xD;
             serotonin reuptake inhibitors (SSRIs) for a least 3 months&#xD;
&#xD;
          -  Any concurrent cognitive behavioral therapy; other psychotherapy that was initiated in&#xD;
             the past 3 months&#xD;
&#xD;
          -  Pregnancy, or plans to become pregnant during the period of the study - will be&#xD;
             assessed by Urine β-HCG&#xD;
&#xD;
          -  Contraindication to MRI scanning:&#xD;
&#xD;
          -  Paramagnetic metallic implants or devices contraindicating magnetic resonance imaging&#xD;
             or any other non-removable paramagnetic metal in the body (e.g. pacemaker,&#xD;
             paramagnetic metallic prosthesis, surgical clips, shrapnel, necessity for constant&#xD;
             medicinal patch, some tattoos)&#xD;
&#xD;
          -  Being unable to tolerate the scanning procedures (i.e., severe obesity,&#xD;
             claustrophobia)&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>60 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Franklin Schneier, MD</last_name>
    <role>Principal Investigator</role>
    <affiliation>NYSPI</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>New York State Psychiatric Institute</name>
      <address>
        <city>New York</city>
        <state>New York</state>
        <zip>10032</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>United States</country>
  </location_countries>
  <reference>
    <citation>Chevallier C, Tonge N, Safra L, Kahn D, Kohls G, Miller J, Schultz RT. Measuring Social Motivation Using Signal Detection and Reward Responsiveness. PLoS One. 2016 Dec 1;11(12):e0167024. doi: 10.1371/journal.pone.0167024. eCollection 2016.</citation>
    <PMID>27907025</PMID>
  </reference>
  <reference>
    <citation>Cisler JM, Koster EH. Mechanisms of attentional biases towards threat in anxiety disorders: An integrative review. Clin Psychol Rev. 2010 Mar;30(2):203-16. doi: 10.1016/j.cpr.2009.11.003. Epub 2009 Dec 14.</citation>
    <PMID>20005616</PMID>
  </reference>
  <reference>
    <citation>Gur RC, Schroeder L, Turner T, McGrath C, Chan RM, Turetsky BI, Alsop D, Maldjian J, Gur RE. Brain activation during facial emotion processing. Neuroimage. 2002 Jul;16(3 Pt 1):651-62. doi: 10.1006/nimg.2002.1097.</citation>
    <PMID>12169250</PMID>
  </reference>
  <reference>
    <citation>Heeren A, Mogoase C, Philippot P, McNally RJ. Attention bias modification for social anxiety: A systematic review and meta-analysis. Clin Psychol Rev. 2015 Aug;40:76-90. doi: 10.1016/j.cpr.2015.06.001. Epub 2015 Jun 6.</citation>
    <PMID>26080314</PMID>
  </reference>
  <reference>
    <citation>Klumpp H, Angstadt M, Phan KL. Shifting the focus of attention modulates amygdala and anterior cingulate cortex reactivity to emotional faces. Neurosci Lett. 2012 Apr 18;514(2):210-3. doi: 10.1016/j.neulet.2012.03.003. Epub 2012 Mar 8.</citation>
    <PMID>22425719</PMID>
  </reference>
  <reference>
    <citation>Klumpp H, Post D, Angstadt M, Fitzgerald DA, Phan KL. Anterior cingulate cortex and insula response during indirect and direct processing of emotional faces in generalized social anxiety disorder. Biol Mood Anxiety Disord. 2013 Apr 2;3:7. doi: 10.1186/2045-5380-3-7. eCollection 2013.</citation>
    <PMID>23547713</PMID>
  </reference>
  <reference>
    <citation>Lazarov A, Abend R, Bar-Haim Y. Social anxiety is related to increased dwell time on socially threatening faces. J Affect Disord. 2016 Mar 15;193:282-8. doi: 10.1016/j.jad.2016.01.007. Epub 2016 Jan 12.</citation>
    <PMID>26774515</PMID>
  </reference>
  <reference>
    <citation>Lazarov A, Pine DS, Bar-Haim Y. Gaze-Contingent Music Reward Therapy for Social Anxiety Disorder: A Randomized Controlled Trial. Am J Psychiatry. 2017 Jul 1;174(7):649-656. doi: 10.1176/appi.ajp.2016.16080894. Epub 2017 Jan 20.</citation>
    <PMID>28103714</PMID>
  </reference>
  <reference>
    <citation>Linetzky M, Pergamin-Hight L, Pine DS, Bar-Haim Y. Quantitative evaluation of the clinical efficacy of attention bias modification treatment for anxiety disorders. Depress Anxiety. 2015 Jun;32(6):383-91. doi: 10.1002/da.22344. Epub 2015 Feb 24. Erratum In: Depress Anxiety. 2018 Jan;35(1):111-112.</citation>
    <PMID>25708991</PMID>
  </reference>
  <reference>
    <citation>Mogoase C, David D, Koster EH. Clinical efficacy of attentional bias modification procedures: an updated meta-analysis. J Clin Psychol. 2014 Dec;70(12):1133-57. doi: 10.1002/jclp.22081. Epub 2014 Mar 20.</citation>
    <PMID>24652823</PMID>
  </reference>
  <reference>
    <citation>Morrison AS, Heimberg RG. Social anxiety and social anxiety disorder. Annu Rev Clin Psychol. 2013;9:249-74. doi: 10.1146/annurev-clinpsy-050212-185631.</citation>
    <PMID>23537485</PMID>
  </reference>
  <reference>
    <citation>Richey JA, Rittenberg A, Hughes L, Damiano CR, Sabatino A, Miller S, Hanna E, Bodfish JW, Dichter GS. Common and distinct neural features of social and non-social reward processing in autism and social anxiety disorder. Soc Cogn Affect Neurosci. 2014 Mar;9(3):367-77. doi: 10.1093/scan/nss146. Epub 2012 Dec 7.</citation>
    <PMID>23223206</PMID>
  </reference>
  <reference>
    <citation>Spreckelmeyer KN, Krach S, Kohls G, Rademacher L, Irmak A, Konrad K, Kircher T, Grunder G. Anticipation of monetary and social reward differently activates mesolimbic brain structures in men and women. Soc Cogn Affect Neurosci. 2009 Jun;4(2):158-65. doi: 10.1093/scan/nsn051. Epub 2009 Jan 27.</citation>
    <PMID>19174537</PMID>
  </reference>
  <reference>
    <citation>Van Bockstaele B, Verschuere B, Tibboel H, De Houwer J, Crombez G, Koster EH. A review of current evidence for the causal impact of attentional bias on fear and anxiety. Psychol Bull. 2014 May;140(3):682-721. doi: 10.1037/a0034834. Epub 2013 Nov 4.</citation>
    <PMID>24188418</PMID>
  </reference>
  <verification_date>January 2023</verification_date>
  <study_first_submitted>July 25, 2017</study_first_submitted>
  <study_first_submitted_qc>August 3, 2017</study_first_submitted_qc>
  <study_first_posted type="Actual">August 4, 2017</study_first_posted>
  <last_update_submitted>January 20, 2023</last_update_submitted>
  <last_update_submitted_qc>January 20, 2023</last_update_submitted_qc>
  <last_update_posted type="Actual">January 23, 2023</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>New York State Psychiatric Institute</investigator_affiliation>
    <investigator_full_name>Franklin Schneier</investigator_full_name>
    <investigator_title>Research Scientist</investigator_title>
  </responsible_party>
  <keyword>Social Anxiety</keyword>
  <keyword>Social Anxiety Disorder</keyword>
  <keyword>SAD</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Anxiety Disorders</mesh_term>
    <mesh_term>Phobia, Social</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03240003
org study id: 7527 (SAD)
nct id: NCT03240003
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
The present study is a double blind trial that seeks to examine the feasibility,
      acceptability, efficacy, and mechanism of a recently developed eye-tracking-based therapy
      (GC-MRT) in individuals with social anxiety disorder (SAD)
The present study is a double blind trial that seeks to examine the feasibility,
      acceptability, efficacy, and mechanism of a recently developed eye-tracking-based therapy
      (GC-MRT) in individuals with social anxiety disorder (SAD). The purpose of this study is to
      assess whether a brief computer-based research treatment, provided in 30 minutes sessions
      twice a week for 4 weeks, helps improve social anxiety symptoms, and by what mechanism. The
      study will also assess the effect of research treatments on brain activity using a scan
      called magnetic resonance imaging (MRI).
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Basic Science
masking: Triple (Participant, Investigator, Outcomes Assessor)
measure: Liebowitz Social Anxiety Scale
time frame: 4 months
description: Total score of the Liebowitz Social Anxiety Scale
measure: Social Phobia Inventory (SPIN)
time frame: 4 months
description: The Social Phobia Inventory (abbreviated as SPIN) is a self-rated questionnaire that will be used to assess severity of social anxiety Disorder. 17 items related to social anxiety each rated on a score of 0 to 4, with a minimum total score of 0 (least social anxiety), and a maximum total score of 68 (most social anxiety).
measure: Quality of Life Enjoyment & Satisfaction Questionnaire
time frame: 4 months
description: Quality of Life Enjoyment & Satisfaction Questionnaire (Q-LES-Q): self-rated assessment of quality of life. 16 items related to life quality, each rated on a score of 1 (very poor) to 5 (very good), with a minimum total score of 16, and a maximum total score of 80.
measure: Revised Social Anhedonia Scale
time frame: 4 months
description: 40-item self-rated social anhedonia scale. Items are comprised of statements that participants agree or disagree with, by answering "yes"(1), or "no"(0), with some items reverse-coded. The minimum score is 0 (least social anhedonia); maximum score is 40 (most social anhedonia).
measure: Snaith Hamilton Pleasure Scale
time frame: 4 months
description: Snaith Hamilton Pleasure Scale (SHAPS). Fourteen-item self-rated anhedonia scale. Items were comprised of statements that participants rated as "strongly disagree" (1), "disagree" (2), "agree" (3), or "strongly agree" (4). The lowest possible score was 14, the highest possible score was 56 (greatest anhedonia)
measure: Hamilton Rating Scale for Depression - 17 item version
time frame: 4 months
description: Hamilton Rating Scale for Depression -17 item version. This standard scale will be used to assess severity of depression, minimum score is 0 (least depression); maximum score is 50 (greatest depression).
measure: Clinical Global Impression-Change Scale
time frame: 4 months
description: Clinical Global Impression-Change Scale: A quickly administered and widely used observer rating, with rating from 1 (very much improved) to 7 (very much worse). Responder category is defined by a score of 1 or 2.
arm group label: GC-MRT
arm group type: Experimental
description: Group 1 will receive a 4-week (8-sessions) course of standard GC-MRT
arm group label: non-GC-MRT
arm group type: Active Comparator
description: Group 2 will receive a 4-week (8-sessions) course of non-GC-MRT
arm group label: GC-MRT-modified
arm group type: Experimental
description: Group 3 will receive a 4-week (8-sessions) course of modified GC-MRT.
intervention type: Behavioral
intervention name: GC-MRT
description: Group 1 will receive a 4-week (8-sessions) course of GC-MRT
arm group label: GC-MRT
intervention type: Behavioral
intervention name: modified GC-MRT
description: group 3 will receive a 4-week (8-sessions) course of GC-MRT, modified
arm group label: GC-MRT-modified
intervention type: Behavioral
intervention name: Non-GC-MRT
description: Group 2 will receive a 4-week (8-sessions) course of non-GC-MRT
arm group label: non-GC-MRT
criteria: 
gender: All
minimum age: 18 Years
maximum age: 60 Years
healthy volunteers: No
last name: Franklin Schneier, MD
role: Principal Investigator
affiliation: NYSPI
facility: 
country: United States
citation: Chevallier C, Tonge N, Safra L, Kahn D, Kohls G, Miller J, Schultz RT. Measuring Social Motivation Using Signal Detection and Reward Responsiveness. PLoS One. 2016 Dec 1;11(12):e0167024. doi: 10.1371/journal.pone.0167024. eCollection 2016.
PMID: 27907025
citation: Cisler JM, Koster EH. Mechanisms of attentional biases towards threat in anxiety disorders: An integrative review. Clin Psychol Rev. 2010 Mar;30(2):203-16. doi: 10.1016/j.cpr.2009.11.003. Epub 2009 Dec 14.
PMID: 20005616
citation: Gur RC, Schroeder L, Turner T, McGrath C, Chan RM, Turetsky BI, Alsop D, Maldjian J, Gur RE. Brain activation during facial emotion processing. Neuroimage. 2002 Jul;16(3 Pt 1):651-62. doi: 10.1006/nimg.2002.1097.
PMID: 12169250
citation: Heeren A, Mogoase C, Philippot P, McNally RJ. Attention bias modification for social anxiety: A systematic review and meta-analysis. Clin Psychol Rev. 2015 Aug;40:76-90. doi: 10.1016/j.cpr.2015.06.001. Epub 2015 Jun 6.
PMID: 26080314
citation: Klumpp H, Angstadt M, Phan KL. Shifting the focus of attention modulates amygdala and anterior cingulate cortex reactivity to emotional faces. Neurosci Lett. 2012 Apr 18;514(2):210-3. doi: 10.1016/j.neulet.2012.03.003. Epub 2012 Mar 8.
PMID: 22425719
citation: Klumpp H, Post D, Angstadt M, Fitzgerald DA, Phan KL. Anterior cingulate cortex and insula response during indirect and direct processing of emotional faces in generalized social anxiety disorder. Biol Mood Anxiety Disord. 2013 Apr 2;3:7. doi: 10.1186/2045-5380-3-7. eCollection 2013.
PMID: 23547713
citation: Lazarov A, Abend R, Bar-Haim Y. Social anxiety is related to increased dwell time on socially threatening faces. J Affect Disord. 2016 Mar 15;193:282-8. doi: 10.1016/j.jad.2016.01.007. Epub 2016 Jan 12.
PMID: 26774515
citation: Lazarov A, Pine DS, Bar-Haim Y. Gaze-Contingent Music Reward Therapy for Social Anxiety Disorder: A Randomized Controlled Trial. Am J Psychiatry. 2017 Jul 1;174(7):649-656. doi: 10.1176/appi.ajp.2016.16080894. Epub 2017 Jan 20.
PMID: 28103714
citation: Linetzky M, Pergamin-Hight L, Pine DS, Bar-Haim Y. Quantitative evaluation of the clinical efficacy of attention bias modification treatment for anxiety disorders. Depress Anxiety. 2015 Jun;32(6):383-91. doi: 10.1002/da.22344. Epub 2015 Feb 24. Erratum In: Depress Anxiety. 2018 Jan;35(1):111-112.
PMID: 25708991
citation: Mogoase C, David D, Koster EH. Clinical efficacy of attentional bias modification procedures: an updated meta-analysis. J Clin Psychol. 2014 Dec;70(12):1133-57. doi: 10.1002/jclp.22081. Epub 2014 Mar 20.
PMID: 24652823
citation: Morrison AS, Heimberg RG. Social anxiety and social anxiety disorder. Annu Rev Clin Psychol. 2013;9:249-74. doi: 10.1146/annurev-clinpsy-050212-185631.
PMID: 23537485
citation: Richey JA, Rittenberg A, Hughes L, Damiano CR, Sabatino A, Miller S, Hanna E, Bodfish JW, Dichter GS. Common and distinct neural features of social and non-social reward processing in autism and social anxiety disorder. Soc Cogn Affect Neurosci. 2014 Mar;9(3):367-77. doi: 10.1093/scan/nss146. Epub 2012 Dec 7.
PMID: 23223206
citation: Spreckelmeyer KN, Krach S, Kohls G, Rademacher L, Irmak A, Konrad K, Kircher T, Grunder G. Anticipation of monetary and social reward differently activates mesolimbic brain structures in men and women. Soc Cogn Affect Neurosci. 2009 Jun;4(2):158-65. doi: 10.1093/scan/nsn051. Epub 2009 Jan 27.
PMID: 19174537
citation: Van Bockstaele B, Verschuere B, Tibboel H, De Houwer J, Crombez G, Koster EH. A review of current evidence for the causal impact of attentional bias on fear and anxiety. Psychol Bull. 2014 May;140(3):682-721. doi: 10.1037/a0034834. Epub 2013 Nov 4.
PMID: 24188418
responsible party type: Principal Investigator
investigator affiliation: New York State Psychiatric Institute
investigator full name: Franklin Schneier
investigator title: Research Scientist
mesh term: Anxiety Disorders
mesh term: Phobia, Social
sharing ipd: No