<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03254290</url>
  </required_header>
  <id_info>
    <org_study_id>TexasAMBaylor</org_study_id>
    <nct_id>NCT03254290</nct_id>
  </id_info>
  <brief_title>Color Stability of NeoMTA Pulpotomized Primary Teeth</brief_title>
  <official_title>Color Stability of NeoMTA Pulpotomized Primary Teeth</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Texas A &amp; M University Baylor College Of Dentistry</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>Texas A &amp; M University Baylor College Of Dentistry</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      This randomized control study will use 15 pediatric subjects selected from the patient&#xD;
      population in the pediatric dental clinic at Children's Medical Center Dental Clinic (CMC&#xD;
      Dental Clinic). The study will use a within-subject control design whereby one tooth will be&#xD;
      treated with a pulpotomy using the new formulation of MTA (NeoMTA Plus, Avalon Biomed Inc.,&#xD;
      Bradenton, FL, USA) and restored with a multi-surface composite, and the other tooth with a&#xD;
      formocresol pulpotomy and restored with a multi-surface composite; thus, approximately 15&#xD;
      teeth will be treated for each treatment group. The specific treated tooth will be randomized&#xD;
      as to which side will receive the MTA or formocresol using sealed, opaque envelopes.&#xD;
      Approximately 15 subjects will be needed for the study in order to elicit any significant&#xD;
      findings as demonstrated by a power analysis.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Each of the 15 patients will represent a pair of teeth. Within a given patient, assignment of&#xD;
      the first tooth to either treatment will be determined randomly by selecting a sealed, opaque&#xD;
      envelope with a designated treatment, with another tooth being assigned to the other&#xD;
      treatment. All patients must demonstrate sufficient cooperation for treatment and follow-up&#xD;
      radiographs. All procedures, possible risks or discomforts, in addition to possible benefits&#xD;
      will be explained to the parents of all patients involved, and informed consent will be&#xD;
      obtained from each parent.&#xD;
&#xD;
      The goal will consist of completing all treatment in one appointment; however, in the event&#xD;
      that all treatment is unable to be completed, for example, local anesthetic limitations, the&#xD;
      patient will be scheduled for the next available appointment, keeping them as close together&#xD;
      as possible.&#xD;
&#xD;
      Patients will be anesthetized with local anesthesia, and treatment will be performed&#xD;
      utilizing rubber dam isolation. The pulpotomy procedure will include removal of the carious&#xD;
      tooth structure using a high-speed carbide bur and water spray. When the removal of carious&#xD;
      tooth structure results in pulp exposure, the roof of the chamber will be removed. A&#xD;
      high-speed handpiece and sterile spoon excavator will be used to remove the coronal pulp&#xD;
      tissue. The amputation site will be cleaned and hemostasis obtained with a wet cotton pellet.&#xD;
      The site will then be treated with either a slurry of NeoMTA Plus according to the&#xD;
      manufacturer's directions or traditional Formocresol according to the manufacturer's&#xD;
      directions. The remaining pulp chamber will be filled with a visible light cured&#xD;
      resin-reinforced glass ionomer and will then receive a multi-surface composite final&#xD;
      restoration&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Not yet recruiting</last_known_status>
  <start_date type="Anticipated">October 1, 2017</start_date>
  <completion_date type="Anticipated">June 30, 2018</completion_date>
  <primary_completion_date type="Anticipated">June 30, 2018</primary_completion_date>
  <phase>Early Phase 1</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Single Group Assignment</intervention_model>
    <intervention_model_description>Children between the ages of 2 ½ and 9 years of age and be ASA I or ASA II. Patient must have two, primary teeth that are matched for, size of carious lesion (same level of approximation of carious lesion to the pulp) and are that are treatment planned for a pulpotomy. The teeth selected for the study must be vital and asymptomatic both clinically and radiographically or only display symptoms consistent with reversible pulptitis The teeth selected for the study must be anticipated to be retained in the mouth for at least eighteen months</intervention_model_description>
    <primary_purpose>Treatment</primary_purpose>
    <masking>Single (Participant)</masking>
    <masking_description>The teeth treated with each specific material will be randomly assigned by drawing a random number from a manilla folder</masking_description>
  </study_design_info>
  <primary_outcome>
    <measure>Color stability</measure>
    <time_frame>3 month recall</time_frame>
    <description>color scale (0=white/still esthetic; 1=slightly gray; 2=medium gray color; 3=dark gray</description>
  </primary_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Anticipated">15</enrollment>
  <condition>Dental Caries Extending to Pulp</condition>
  <arm_group>
    <arm_group_label>Experimental NeoMTA</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>The new formulation of MTA (does not contain bismuth oxide) will be used in one tooth receiving a pulpotomy to determine if the color of the tooth changes over time.The new formulation has received the FDAs 510(k) substantial equivalence clearance for Class II dental materials and is equivalent to its MTA predicate (ProRoot, Dentsply Tulsa Dental, Tulsa, OK, USA).</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Formocresol</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>Control group. This group will receive the &quot;gold standard&quot; formulation of a formocresol pulpotomy.</description>
  </arm_group>
  <intervention>
    <intervention_type>Biological</intervention_type>
    <intervention_name>NeoMTA</intervention_name>
    <description>A new formulation of MTA was developed in which bismuth oxide was omitted.</description>
    <arm_group_label>Experimental NeoMTA</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Biological</intervention_type>
    <intervention_name>Formocresol</intervention_name>
    <description>Control group</description>
    <arm_group_label>Experimental NeoMTA</arm_group_label>
    <arm_group_label>Formocresol</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
        Children between the ages of 2 ½ and 9 years of age and be ASA I or ASA II. Patient must&#xD;
        have two, primary teeth that are matched for, size of carious lesion (same level of&#xD;
        approximation of carious lesion to the pulp) and are that are treatment planned for a&#xD;
        pulpotomy. The teeth selected for the study must be vital and asymptomatic both clinically&#xD;
        and radiographically or only display symptoms consistent with reversible pulptitis The&#xD;
        teeth selected for the study must be anticipated to be retained in the mouth for at least&#xD;
        eighteen months&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
        Teeth with a history of spontaneous pain. Teeth with radiographic evidence of internal or&#xD;
        external resorption, intraradicular or periapical bone loss, loss of lamina dura, or&#xD;
        widening of the periodontal ligament space&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>30 Months</minimum_age>
    <maximum_age>9 Years</maximum_age>
    <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
  </eligibility>
  <link>
    <url>http://www.accessdata.fda.gov/cdrh_docs/pdf14/K140955.pdf</url>
    <description>Avalon Biomed Inc 2014</description>
  </link>
  <results_reference>
    <citation>Agamy HA, Bakry NS, Mounir MM, Avery DR. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. Pediatr Dent. 2004 Jul-Aug;26(4):302-9.</citation>
    <PMID>15344622</PMID>
  </results_reference>
  <results_reference>
    <citation>Farsi N, Alamoudi N, Balto K, Mushayt A. Success of mineral trioxide aggregate in pulpotomized primary molars. J Clin Pediatr Dent. 2005 Summer;29(4):307-11. doi: 10.17796/jcpd.29.4.n80t77w625118k73.</citation>
    <PMID>16161395</PMID>
  </results_reference>
  <results_reference>
    <citation>Holan G, Eidelman E, Fuks AB. Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. Pediatr Dent. 2005 Mar-Apr;27(2):129-36.</citation>
    <PMID>15926290</PMID>
  </results_reference>
  <results_reference>
    <citation>Jabbarifar SE, Khademi D, Ghasemi D. Success rates of formocresol pulpotomy versus mineral trioxide aggregate in human primary molar tooth. J Res Med Sci 2004; 9(6)L 55-8.</citation>
  </results_reference>
  <results_reference>
    <citation>Peng L, Ye L, Tan H, Zhou X. Evaluation of the formocresol versus mineral trioxide aggregate primary molar pulpotomy: a meta-analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):e40-4. doi: 10.1016/j.tripleo.2006.05.017. Epub 2006 Sep 26.</citation>
    <PMID>17138165</PMID>
  </results_reference>
  <results_reference>
    <citation>Farooq NS, Coll JA, Kuwabara A, Shelton P. Success rates of formocresol pulpotomy and indirect pulp therapy in the treatment of deep dentinal caries in primary teeth. Pediatr Dent. 2000 Jul-Aug;22(4):278-86.</citation>
    <PMID>10969431</PMID>
  </results_reference>
  <results_reference>
    <citation>Guelmann M, Fair J, Bimstein E. Permanent versus temporary restorations after emergency pulpotomies in primary molars. Pediatr Dent. 2005 Nov-Dec;27(6):478-81.</citation>
    <PMID>16532888</PMID>
  </results_reference>
  <results_reference>
    <citation>Holan G, Fuks AB, Ketlz N. Success rate of formocresol pulpotomy in primary molars restored with stainless steel crown vs amalga. Pediatr Dent. 2002 May-Jun;24(3):212-6.</citation>
    <PMID>12064493</PMID>
  </results_reference>
  <results_reference>
    <citation>Seale NS. The use of stainless steel crowns. Pediatr Dent. 2002 Sep-Oct;24(5):501-5.</citation>
    <PMID>12412965</PMID>
  </results_reference>
  <results_reference>
    <citation>Caceda JH. The use of resin-based composite restorations in pulpotomized primary molars. J Dent Child (Chic). 2007 May-Aug;74(2):147-50.</citation>
    <PMID>18477438</PMID>
  </results_reference>
  <results_reference>
    <citation>Cehreli ZC, Cetinguc A, Cengiz SB, Altay AN. Clinical performance of pulpotomized primary molars restored with resin-based materials. 24-month results. Am J Dent. 2006 Oct;19(5):262-6.</citation>
    <PMID>17073200</PMID>
  </results_reference>
  <results_reference>
    <citation>Guelmann M, Bookmyer KL, Villalta P, Garcia-Godoy F. Microleakage of restorative techniques for pulpotomized primary molars. J Dent Child (Chic). 2004 Sep-Dec;71(3):209-11.</citation>
    <PMID>15871455</PMID>
  </results_reference>
  <results_reference>
    <citation>Guelmann M, McIlwain MF, Primosch RE. Radiographic assessment of primary molar pulpotomies restored with resin-based materials. Pediatr Dent. 2005 Jan-Feb;27(1):24-7.</citation>
    <PMID>15839391</PMID>
  </results_reference>
  <results_reference>
    <citation>Hutcheson C, Seale NS, McWhorter A, Kerins C, Wright J. Multi-surface composite vs stainless steel crown restorations after mineral trioxide aggregate pulpotomy: a randomized controlled trial. Pediatr Dent. 2012 Nov-Dec;34(7):460-7.</citation>
    <PMID>23265162</PMID>
  </results_reference>
  <results_reference>
    <citation>Maroto M, Barberia E, Planells P, Garcia Godoy F. Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth. Am J Dent. 2005 Jun;18(3):151-4.</citation>
    <PMID>16158803</PMID>
  </results_reference>
  <results_reference>
    <citation>Parirokh M, Asgary S, Eghbal MJ, Stowe S, Eslami B, Eskandarizade A, Shabahang S. A comparative study of white and grey mineral trioxide aggregate as pulp capping agents in dog's teeth. Dent Traumatol. 2005 Jun;21(3):150-4. doi: 10.1111/j.1600-9657.2005.00311.x.</citation>
    <PMID>15876326</PMID>
  </results_reference>
  <results_reference>
    <citation>Holland R, de Souza V, Murata SS, Nery MJ, Bernabe PF, Otoboni Filho JA, Dezan Junior E. Healing process of dog dental pulp after pulpotomy and pulp covering with mineral trioxide aggregate or Portland cement. Braz Dent J. 2001;12(2):109-13.</citation>
    <PMID>11445912</PMID>
  </results_reference>
  <results_reference>
    <citation>Maroto M, Barberia E, Vera V, Garcia-Godoy F. Dentin bridge formation after white mineral trioxide aggregate (white MTA) pulpotomies in primary molars. Am J Dent. 2006 Apr;19(2):75-9.</citation>
    <PMID>16764128</PMID>
  </results_reference>
  <results_reference>
    <citation>Walsh RM, Woodmansey KF, Glickman GN, He J. Evaluation of compressive strength of hydraulic silicate-based root-end filling materials. J Endod. 2014 Jul;40(7):969-72. doi: 10.1016/j.joen.2013.11.018. Epub 2014 Jan 14.</citation>
    <PMID>24935545</PMID>
  </results_reference>
  <verification_date>August 2017</verification_date>
  <study_first_submitted>August 15, 2017</study_first_submitted>
  <study_first_submitted_qc>August 17, 2017</study_first_submitted_qc>
  <study_first_posted type="Actual">August 18, 2017</study_first_posted>
  <last_update_submitted>August 17, 2017</last_update_submitted>
  <last_update_submitted_qc>August 17, 2017</last_update_submitted_qc>
  <last_update_posted type="Actual">August 18, 2017</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>Texas A &amp; M University Baylor College Of Dentistry</investigator_affiliation>
    <investigator_full_name>Carolyn A. Kerins DDS</investigator_full_name>
    <investigator_title>Principal Investigator</investigator_title>
  </responsible_party>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Dental Caries</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>Undecided</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03254290
org study id: TexasAMBaylor
nct id: NCT03254290
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
This randomized control study will use 15 pediatric subjects selected from the patient
      population in the pediatric dental clinic at Children's Medical Center Dental Clinic (CMC
      Dental Clinic). The study will use a within-subject control design whereby one tooth will be
      treated with a pulpotomy using the new formulation of MTA (NeoMTA Plus, Avalon Biomed Inc.,
      Bradenton, FL, USA) and restored with a multi-surface composite, and the other tooth with a
      formocresol pulpotomy and restored with a multi-surface composite; thus, approximately 15
      teeth will be treated for each treatment group. The specific treated tooth will be randomized
      as to which side will receive the MTA or formocresol using sealed, opaque envelopes.
      Approximately 15 subjects will be needed for the study in order to elicit any significant
      findings as demonstrated by a power analysis.
Each of the 15 patients will represent a pair of teeth. Within a given patient, assignment of
      the first tooth to either treatment will be determined randomly by selecting a sealed, opaque
      envelope with a designated treatment, with another tooth being assigned to the other
      treatment. All patients must demonstrate sufficient cooperation for treatment and follow-up
      radiographs. All procedures, possible risks or discomforts, in addition to possible benefits
      will be explained to the parents of all patients involved, and informed consent will be
      obtained from each parent.

      The goal will consist of completing all treatment in one appointment; however, in the event
      that all treatment is unable to be completed, for example, local anesthetic limitations, the
      patient will be scheduled for the next available appointment, keeping them as close together
      as possible.

      Patients will be anesthetized with local anesthesia, and treatment will be performed
      utilizing rubber dam isolation. The pulpotomy procedure will include removal of the carious
      tooth structure using a high-speed carbide bur and water spray. When the removal of carious
      tooth structure results in pulp exposure, the roof of the chamber will be removed. A
      high-speed handpiece and sterile spoon excavator will be used to remove the coronal pulp
      tissue. The amputation site will be cleaned and hemostasis obtained with a wet cotton pellet.
      The site will then be treated with either a slurry of NeoMTA Plus according to the
      manufacturer's directions or traditional Formocresol according to the manufacturer's
      directions. The remaining pulp chamber will be filled with a visible light cured
      resin-reinforced glass ionomer and will then receive a multi-surface composite final
      restoration
allocation: Randomized
intervention model: Single Group Assignment
intervention model description: Children between the ages of 2 ½ and 9 years of age and be ASA I or ASA II. Patient must have two, primary teeth that are matched for, size of carious lesion (same level of approximation of carious lesion to the pulp) and are that are treatment planned for a pulpotomy. The teeth selected for the study must be vital and asymptomatic both clinically and radiographically or only display symptoms consistent with reversible pulptitis The teeth selected for the study must be anticipated to be retained in the mouth for at least eighteen months
primary purpose: Treatment
masking: Single (Participant)
masking description: The teeth treated with each specific material will be randomly assigned by drawing a random number from a manilla folder
measure: Color stability
time frame: 3 month recall
description: color scale (0=white/still esthetic; 1=slightly gray; 2=medium gray color; 3=dark gray
arm group label: Experimental NeoMTA
arm group type: Experimental
description: The new formulation of MTA (does not contain bismuth oxide) will be used in one tooth receiving a pulpotomy to determine if the color of the tooth changes over time.The new formulation has received the FDAs 510(k) substantial equivalence clearance for Class II dental materials and is equivalent to its MTA predicate (ProRoot, Dentsply Tulsa Dental, Tulsa, OK, USA).
arm group label: Formocresol
arm group type: Active Comparator
description: Control group. This group will receive the "gold standard" formulation of a formocresol pulpotomy.
intervention type: Biological
intervention name: NeoMTA
description: A new formulation of MTA was developed in which bismuth oxide was omitted.
arm group label: Experimental NeoMTA
intervention type: Biological
intervention name: Formocresol
description: Control group
arm group label: Experimental NeoMTA
arm group label: Formocresol
criteria: 
gender: All
minimum age: 30 Months
maximum age: 9 Years
healthy volunteers: Accepts Healthy Volunteers
url: http://www.accessdata.fda.gov/cdrh_docs/pdf14/K140955.pdf
description: Avalon Biomed Inc 2014
citation: Agamy HA, Bakry NS, Mounir MM, Avery DR. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. Pediatr Dent. 2004 Jul-Aug;26(4):302-9.
PMID: 15344622
citation: Farsi N, Alamoudi N, Balto K, Mushayt A. Success of mineral trioxide aggregate in pulpotomized primary molars. J Clin Pediatr Dent. 2005 Summer;29(4):307-11. doi: 10.17796/jcpd.29.4.n80t77w625118k73.
PMID: 16161395
citation: Holan G, Eidelman E, Fuks AB. Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. Pediatr Dent. 2005 Mar-Apr;27(2):129-36.
PMID: 15926290
citation: Jabbarifar SE, Khademi D, Ghasemi D. Success rates of formocresol pulpotomy versus mineral trioxide aggregate in human primary molar tooth. J Res Med Sci 2004; 9(6)L 55-8.
citation: Peng L, Ye L, Tan H, Zhou X. Evaluation of the formocresol versus mineral trioxide aggregate primary molar pulpotomy: a meta-analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):e40-4. doi: 10.1016/j.tripleo.2006.05.017. Epub 2006 Sep 26.
PMID: 17138165
citation: Farooq NS, Coll JA, Kuwabara A, Shelton P. Success rates of formocresol pulpotomy and indirect pulp therapy in the treatment of deep dentinal caries in primary teeth. Pediatr Dent. 2000 Jul-Aug;22(4):278-86.
PMID: 10969431
citation: Guelmann M, Fair J, Bimstein E. Permanent versus temporary restorations after emergency pulpotomies in primary molars. Pediatr Dent. 2005 Nov-Dec;27(6):478-81.
PMID: 16532888
citation: Holan G, Fuks AB, Ketlz N. Success rate of formocresol pulpotomy in primary molars restored with stainless steel crown vs amalga. Pediatr Dent. 2002 May-Jun;24(3):212-6.
PMID: 12064493
citation: Seale NS. The use of stainless steel crowns. Pediatr Dent. 2002 Sep-Oct;24(5):501-5.
PMID: 12412965
citation: Caceda JH. The use of resin-based composite restorations in pulpotomized primary molars. J Dent Child (Chic). 2007 May-Aug;74(2):147-50.
PMID: 18477438
citation: Cehreli ZC, Cetinguc A, Cengiz SB, Altay AN. Clinical performance of pulpotomized primary molars restored with resin-based materials. 24-month results. Am J Dent. 2006 Oct;19(5):262-6.
PMID: 17073200
citation: Guelmann M, Bookmyer KL, Villalta P, Garcia-Godoy F. Microleakage of restorative techniques for pulpotomized primary molars. J Dent Child (Chic). 2004 Sep-Dec;71(3):209-11.
PMID: 15871455
citation: Guelmann M, McIlwain MF, Primosch RE. Radiographic assessment of primary molar pulpotomies restored with resin-based materials. Pediatr Dent. 2005 Jan-Feb;27(1):24-7.
PMID: 15839391
citation: Hutcheson C, Seale NS, McWhorter A, Kerins C, Wright J. Multi-surface composite vs stainless steel crown restorations after mineral trioxide aggregate pulpotomy: a randomized controlled trial. Pediatr Dent. 2012 Nov-Dec;34(7):460-7.
PMID: 23265162
citation: Maroto M, Barberia E, Planells P, Garcia Godoy F. Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth. Am J Dent. 2005 Jun;18(3):151-4.
PMID: 16158803
citation: Parirokh M, Asgary S, Eghbal MJ, Stowe S, Eslami B, Eskandarizade A, Shabahang S. A comparative study of white and grey mineral trioxide aggregate as pulp capping agents in dog's teeth. Dent Traumatol. 2005 Jun;21(3):150-4. doi: 10.1111/j.1600-9657.2005.00311.x.
PMID: 15876326
citation: Holland R, de Souza V, Murata SS, Nery MJ, Bernabe PF, Otoboni Filho JA, Dezan Junior E. Healing process of dog dental pulp after pulpotomy and pulp covering with mineral trioxide aggregate or Portland cement. Braz Dent J. 2001;12(2):109-13.
PMID: 11445912
citation: Maroto M, Barberia E, Vera V, Garcia-Godoy F. Dentin bridge formation after white mineral trioxide aggregate (white MTA) pulpotomies in primary molars. Am J Dent. 2006 Apr;19(2):75-9.
PMID: 16764128
citation: Walsh RM, Woodmansey KF, Glickman GN, He J. Evaluation of compressive strength of hydraulic silicate-based root-end filling materials. J Endod. 2014 Jul;40(7):969-72. doi: 10.1016/j.joen.2013.11.018. Epub 2014 Jan 14.
PMID: 24935545
responsible party type: Principal Investigator
investigator affiliation: Texas A & M University Baylor College Of Dentistry
investigator full name: Carolyn A. Kerins DDS
investigator title: Principal Investigator
mesh term: Dental Caries
sharing ipd: Undecided