<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03302104</url>
  </required_header>
  <id_info>
    <org_study_id>R01AG033592-01A1</org_study_id>
    <nct_id>NCT03302104</nct_id>
  </id_info>
  <brief_title>Diet Quality and LTL in NHANES</brief_title>
  <official_title>Diet Quality Indices and Leukocyte Telomere Length Among Healthy US Adults: Data From the National Health and Nutrition Examination Surveys (NHANES) 1999-2002</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>University of California, San Francisco</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>University of California, San Francisco</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      In our study, we used data from 4,758 healthy adults from the 1999-2002 National Health and&#xD;
      Nutrition Examination Surveys to examine the associations between evidence-based diet quality&#xD;
      indices and leukocyte telomere length. Our study assessed the four most widely recognized and&#xD;
      commonly used diet quality indices in nutritional epidemiology: the USDA-developed Healthy&#xD;
      Eating Index-2010, the Alternate Healthy Eating Index-2010, the Mediterranean Diet Score, and&#xD;
      the DASH diet score. Analyses were adjusted for sociodemographic and health variables known&#xD;
      to influence dietary intake and cellular aging.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">January 1, 1999</start_date>
  <completion_date type="Actual">December 31, 2002</completion_date>
  <primary_completion_date type="Actual">December 31, 2002</primary_completion_date>
  <study_type>Observational</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <observational_model>Other</observational_model>
    <time_perspective>Cross-Sectional</time_perspective>
  </study_design_info>
  <primary_outcome>
    <measure>Leukocyte telomere length</measure>
    <time_frame>1999-2002</time_frame>
  </primary_outcome>
  <enrollment type="Actual">4758</enrollment>
  <condition>Telomere Length, Mean Leukocyte</condition>
  <condition>Diet Habit</condition>
  <eligibility>
    <study_pop>
      <textblock>
        The study population was comprised of 4,758 healthy adults, aged 20 to 65 years, who had&#xD;
        complete dietary and leukocyte telomere length (LTL) data measured in 1999-2002 National&#xD;
        Health and Nutrition Examination Surveys (NHANES), without a prior diagnosis of major&#xD;
        chronic disease (coronary heart disease, angina, myocardial infarction, stroke, diabetes,&#xD;
        congestive heart failure, and cancer).&#xD;
      </textblock>
    </study_pop>
    <sampling_method>Probability Sample</sampling_method>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Ages 20 to 65 years&#xD;
&#xD;
          -  No prior diagnosis of major chronic disease (coronary heart disease, angina,&#xD;
             myocardial infarction, stroke, diabetes, congestive heart failure, and cancer)&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Prior diagnosis of major chronic disease (coronary heart disease, angina, myocardial&#xD;
             infarction, stroke, diabetes, congestive heart failure, and cancer)&#xD;
&#xD;
          -  Younger than age 20 or older than age 65&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>20 Years</minimum_age>
    <maximum_age>65 Years</maximum_age>
  </eligibility>
  <verification_date>September 2017</verification_date>
  <study_first_submitted>September 22, 2017</study_first_submitted>
  <study_first_submitted_qc>September 29, 2017</study_first_submitted_qc>
  <study_first_posted type="Actual">October 4, 2017</study_first_posted>
  <last_update_submitted>September 29, 2017</last_update_submitted>
  <last_update_submitted_qc>September 29, 2017</last_update_submitted_qc>
  <last_update_posted type="Actual">October 4, 2017</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03302104
org study id: R01AG033592-01A1
nct id: NCT03302104
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
In our study, we used data from 4,758 healthy adults from the 1999-2002 National Health and
      Nutrition Examination Surveys to examine the associations between evidence-based diet quality
      indices and leukocyte telomere length. Our study assessed the four most widely recognized and
      commonly used diet quality indices in nutritional epidemiology: the USDA-developed Healthy
      Eating Index-2010, the Alternate Healthy Eating Index-2010, the Mediterranean Diet Score, and
      the DASH diet score. Analyses were adjusted for sociodemographic and health variables known
      to influence dietary intake and cellular aging.
observational model: Other
time perspective: Cross-Sectional
measure: Leukocyte telomere length
time frame: 1999-2002
study pop: 
sampling method: Probability Sample
criteria: 
gender: All
minimum age: 20 Years
maximum age: 65 Years
responsible party type: Sponsor