<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03251781</url>
  </required_header>
  <id_info>
    <org_study_id>222/2011</org_study_id>
    <secondary_id>063053/2014</secondary_id>
    <nct_id>NCT03251781</nct_id>
  </id_info>
  <brief_title>Minimal Important Difference for the Glittre-ADL Test and London Chest Activity of Daily Living Scale</brief_title>
  <official_title>Determination of Minimal Important Difference for the Glittre-ADL Test and London Chest Activity of Daily Living Scale in Patients With COPD</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>University of the State of Santa Catarina</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
    <collaborator>
      <agency>Federal University of Health Science of Porto Alegre</agency>
      <agency_class>Other</agency_class>
    </collaborator>
  </sponsors>
  <source>University of the State of Santa Catarina</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      Background: The ability to perform activities of daily living (ADL) in patients with chronic&#xD;
      obstructive pulmonary disease is often impaired. Glittre-ADL Test has been used to assess&#xD;
      limitations in ADL, and it seems to be responsive to intervention. However, the minimal&#xD;
      detectable change for Glittre-ADL Test remains unknown. Design: Non-controlled before and&#xD;
      after study. Setting: The study will be conducted in an outpatient pulmonary rehabilitation&#xD;
      program in Florianopolis, Brazil. Subjects: Patients with COPD (GOLD II-IV). Interventions:&#xD;
      Pulmonary rehabilitation program based on physical training, conducted over 24 sessions&#xD;
      supervised, three times a week, including aerobic training in treadmill and localized&#xD;
      training for upper limbs and lower limbs. Main measures: Glittre ADL-Test performance,&#xD;
      six-minute walk test performance, London Chest Activity of Daily Living score, Modified&#xD;
      Medical Research Council score, COPD Assessment Test score, Saint George Respiratory&#xD;
      Questionnaire score before and after the pulmonary rehabilitation program.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Assigned Interventions: Pulmonary rehabilitation program (PRP) was conducted according to the&#xD;
      guidelines of the American Thoracic Society/European Respiratory Society (ATS/ERS). Physical&#xD;
      training was conducted over 24 sessions supervised, three times a week. The program included&#xD;
      aerobic training in treadmill (with 30 min load determined by the dyspnea sensation - 4 to 6&#xD;
      on the modified Borg scale) and localized training for upper limbs with free weights or&#xD;
      elastic bands (movements performed based on the proprioceptive neuromuscular facilitation&#xD;
      diagonals, performed in two series, lasting two minutes each) and lower limbs (quadriceps and&#xD;
      triceps sural) with free weights and/or in the bodybuilding station .&#xD;
&#xD;
      Pulmonary function test: Spirometry will be performed before the PRP, and it will be in&#xD;
      accordance with ATS/ERS standards in order to provide the level of pulmonary obstruction and&#xD;
      severity of disease. The predicted values will be calculated with the equations derived from&#xD;
      Brazilian population.&#xD;
&#xD;
      Glittre-ADL Test: The patients will be instructed to complete five laps on the follow circuit&#xD;
      as quickly as possible: from a sitting position, the subject stands up and walks along a flat&#xD;
      10-m long course, in the middle of which there is a two-step ladder (each step 17 cm high x&#xD;
      27 cm deep) to be climbed; after completing the 10 m, the subject faces a shelf containing&#xD;
      three 1-kg objects positioned on the top shelf (shoulder height) and moves them one by one to&#xD;
      the bottom shelf (waist height) and then to the floor; the objects are then returned to the&#xD;
      bottom shelf and finally to the top shelf again; the subject walks back, climbing up and down&#xD;
      the steps, until reaching the starting point (chair), sits down and immediately begins the&#xD;
      next lap. The subjects carry a weighted backpack (2.5 kg for women, 5.0 kg for men). Two&#xD;
      Glittre-ADL Tests will be conducted before and after the PRP.&#xD;
&#xD;
      Six minute walk test (6MWT): The patients will be instructed to walk in order to perform the&#xD;
      largest distance during six minutes. The walking speed will be selected by the patient,&#xD;
      according to the guidelines of the ATS. Two 6MWTs will be conducted before and after the PRP.&#xD;
&#xD;
      London Chest Activity of Daily Living scale: Patients will be asked about their perception of&#xD;
      limitation in activities of daily living, using the London Chest Activity of Daily Living&#xD;
      scale (LCADL) before and after the PRP.&#xD;
&#xD;
      Modified Medical Research Council scale: Patients will be asked about their perception of&#xD;
      dyspnea, using the modified Medical Research Council scale before and after the PRP.&#xD;
&#xD;
      Saint George Respiratory Questionnaire: Patients will be asked about their perception of&#xD;
      health-related quality of life, using the Saint George Respiratory Questionnaire before and&#xD;
      after the PRP.&#xD;
&#xD;
      COPD Assessment Test (CAT): Patients will be asked about their perception of the impact of&#xD;
      COPD (cough, sputum, dyspnea, and chest tightness) on health status, using CAT before and&#xD;
      after the PRP.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">April 1, 2013</start_date>
  <completion_date type="Actual">November 30, 2017</completion_date>
  <primary_completion_date type="Actual">May 31, 2017</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>N/A</allocation>
    <intervention_model>Single Group Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Glittre ADL-Test</measure>
    <time_frame>The change in the Glittre ADL-test performance from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).</time_frame>
    <description>Change in Glittre ADL-Test performance</description>
  </primary_outcome>
  <primary_outcome>
    <measure>London Chest Activity of Daily Living</measure>
    <time_frame>The change in the London Chest Activity of Daily Living score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).</time_frame>
    <description>Change in London Chest Activity of Daily Living score</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Six-minute walking test</measure>
    <time_frame>The change in the distance walked during the six-minute walking test from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).</time_frame>
    <description>Change in six-minute walking test performance</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Modified Medical Research Council</measure>
    <time_frame>The change in the Modified Medical Research Council score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).</time_frame>
    <description>Change in Modified Medical Research Council score</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>COPD Assessment Test (CAT)</measure>
    <time_frame>The change in the COPD Assessment Test (CAT) score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).</time_frame>
    <description>Change in COPD Assessment Test (CAT) score</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Saint George Respiratory Questionnaire (SGRQ)</measure>
    <time_frame>The change in the Saint George Respiratory Questionnaire (SGRQ) score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).</time_frame>
    <description>Change in Saint George Respiratory Questionnaire (SGRQ) score</description>
  </secondary_outcome>
  <number_of_arms>1</number_of_arms>
  <enrollment type="Actual">77</enrollment>
  <condition>Pulmonary Disease, Chronic Obstructive</condition>
  <arm_group>
    <arm_group_label>Pulmonary Rehabilitation</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Pulmonary Rehabilitation</description>
  </arm_group>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Pulmonary Rehabilitation</intervention_name>
    <description>Pulmonary rehabilitation program (PRP) was conducted according to the guidelines of the American Thoracic Society/European Respiratory Society (Nici et al., 2006; Spruit et al., 2013). Physical training was conducted over 24 sessions supervised, three times a week. The program included aerobic training in treadmill (with 30 min load determined by the dyspnea sensation - 4 to 6 on the modified Borg scale) and localized training for upper limbs with free weights or elastic bands (movements performed based on the proprioceptive neuromuscular facilitation diagonals, performed in two series, lasting two minutes each) and lower limbs (quadriceps and triceps sural) with free weights and/or in the bodybuilding station.</description>
    <arm_group_label>Pulmonary Rehabilitation</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Clinical diagnosis of COPD confirmed by spirometry (COPD GOLD stages II, III and IV)&#xD;
&#xD;
          -  Absence of change in respiratory symptoms in the past four weeks&#xD;
&#xD;
          -  No hospital admission in the past 12 weeks&#xD;
&#xD;
          -  Age between 40 and 80 years old&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Any other disease or health condition that could compromise the test´s execution or&#xD;
             physical training&#xD;
&#xD;
          -  Participation in pulmonary rehabilitation program completed in the last six months&#xD;
&#xD;
          -  Interruption of pulmonary rehabilitation program for any reason&#xD;
&#xD;
          -  Current smoking or its cessation in less than six months&#xD;
&#xD;
          -  Any change in symptoms during the study protocol assessments&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>40 Years</minimum_age>
    <maximum_age>80 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Anamaria F Mayer, PhD</last_name>
    <role>Principal Investigator</role>
    <affiliation>University of the State of Santa Catarina</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Universidade Federal de Ciências da Saúde de Porto Alegre</name>
      <address>
        <city>Porto Alegre</city>
        <state>Rio Grande Do Sul</state>
        <zip>90050-170</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>University of the State of Santa Catarina</name>
      <address>
        <city>Florianópolis</city>
        <state>Santa Catarina</state>
        <zip>88080-350</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Brazil</country>
  </location_countries>
  <reference>
    <citation>Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, Carone M, Celli B, Engelen M, Fahy B, Garvey C, Goldstein R, Gosselink R, Lareau S, MacIntyre N, Maltais F, Morgan M, O'Donnell D, Prefault C, Reardon J, Rochester C, Schols A, Singh S, Troosters T; ATS/ERS Pulmonary Rehabilitation Writing Committee. American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. Am J Respir Crit Care Med. 2006 Jun 15;173(12):1390-413. doi: 10.1164/rccm.200508-1211ST. No abstract available.</citation>
    <PMID>16760357</PMID>
  </reference>
  <reference>
    <citation>Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, Hill K, Holland AE, Lareau SC, Man WD, Pitta F, Sewell L, Raskin J, Bourbeau J, Crouch R, Franssen FM, Casaburi R, Vercoulen JH, Vogiatzis I, Gosselink R, Clini EM, Effing TW, Maltais F, van der Palen J, Troosters T, Janssen DJ, Collins E, Garcia-Aymerich J, Brooks D, Fahy BF, Puhan MA, Hoogendoorn M, Garrod R, Schols AM, Carlin B, Benzo R, Meek P, Morgan M, Rutten-van Molken MP, Ries AL, Make B, Goldstein RS, Dowson CA, Brozek JL, Donner CF, Wouters EF; ATS/ERS Task Force on Pulmonary Rehabilitation. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med. 2013 Oct 15;188(8):e13-64. doi: 10.1164/rccm.201309-1634ST. Erratum In: Am J Respir Crit Care Med. 2014 Jun 15;189(12):1570.</citation>
    <PMID>24127811</PMID>
  </reference>
  <reference>
    <citation>Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J; ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J. 2005 Aug;26(2):319-38. doi: 10.1183/09031936.05.00034805. No abstract available.</citation>
    <PMID>16055882</PMID>
  </reference>
  <reference>
    <citation>Garrod R, Bestall JC, Paul EA, Wedzicha JA, Jones PW. Development and validation of a standardized measure of activity of daily living in patients with severe COPD: the London Chest Activity of Daily Living scale (LCADL). Respir Med. 2000 Jun;94(6):589-96. doi: 10.1053/rmed.2000.0786.</citation>
    <PMID>10921765</PMID>
  </reference>
  <reference>
    <citation>Carpes MF, Mayer AF, Simon KM, Jardim JR, Garrod R. The Brazilian Portuguese version of the London Chest Activity of Daily Living scale for use in patients with chronic obstructive pulmonary disease. J Bras Pneumol. 2008 Mar;34(3):143-51. doi: 10.1590/s1806-37132008000300004. English, Portuguese.</citation>
    <PMID>18392462</PMID>
  </reference>
  <reference>
    <citation>Kovelis D, Segretti NO, Probst VS, Lareau SC, Brunetto AF, Pitta F. Validation of the Modified Pulmonary Functional Status and Dyspnea Questionnaire and the Medical Research Council scale for use in Brazilian patients with chronic obstructive pulmonary disease. J Bras Pneumol. 2008 Dec;34(12):1008-18. doi: 10.1590/s1806-37132008001200005. English, Portuguese.</citation>
    <PMID>19180335</PMID>
  </reference>
  <reference>
    <citation>Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N. Development and first validation of the COPD Assessment Test. Eur Respir J. 2009 Sep;34(3):648-54. doi: 10.1183/09031936.00102509.</citation>
    <PMID>19720809</PMID>
  </reference>
  <reference>
    <citation>Holland AE, Spruit MA, Troosters T, Puhan MA, Pepin V, Saey D, McCormack MC, Carlin BW, Sciurba FC, Pitta F, Wanger J, MacIntyre N, Kaminsky DA, Culver BH, Revill SM, Hernandes NA, Andrianopoulos V, Camillo CA, Mitchell KE, Lee AL, Hill CJ, Singh SJ. An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease. Eur Respir J. 2014 Dec;44(6):1428-46. doi: 10.1183/09031936.00150314. Epub 2014 Oct 30.</citation>
    <PMID>25359355</PMID>
  </reference>
  <verification_date>September 2018</verification_date>
  <study_first_submitted>July 28, 2017</study_first_submitted>
  <study_first_submitted_qc>August 15, 2017</study_first_submitted_qc>
  <study_first_posted type="Actual">August 16, 2017</study_first_posted>
  <last_update_submitted>September 6, 2018</last_update_submitted>
  <last_update_submitted_qc>September 6, 2018</last_update_submitted_qc>
  <last_update_posted type="Actual">September 7, 2018</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>University of the State of Santa Catarina</investigator_affiliation>
    <investigator_full_name>Prof. Dra. Anamaria Fleig Mayer</investigator_full_name>
    <investigator_title>Principal Investigator</investigator_title>
  </responsible_party>
  <keyword>Minimal Clinically Important Difference</keyword>
  <keyword>Exercise Test</keyword>
  <keyword>Rehabilitation</keyword>
  <keyword>Disability Evaluation</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Pulmonary Disease, Chronic Obstructive</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03251781
org study id: 222/2011
secondary id: 063053/2014
nct id: NCT03251781
lead sponsor: 
collaborator: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
Background: The ability to perform activities of daily living (ADL) in patients with chronic
      obstructive pulmonary disease is often impaired. Glittre-ADL Test has been used to assess
      limitations in ADL, and it seems to be responsive to intervention. However, the minimal
      detectable change for Glittre-ADL Test remains unknown. Design: Non-controlled before and
      after study. Setting: The study will be conducted in an outpatient pulmonary rehabilitation
      program in Florianopolis, Brazil. Subjects: Patients with COPD (GOLD II-IV). Interventions:
      Pulmonary rehabilitation program based on physical training, conducted over 24 sessions
      supervised, three times a week, including aerobic training in treadmill and localized
      training for upper limbs and lower limbs. Main measures: Glittre ADL-Test performance,
      six-minute walk test performance, London Chest Activity of Daily Living score, Modified
      Medical Research Council score, COPD Assessment Test score, Saint George Respiratory
      Questionnaire score before and after the pulmonary rehabilitation program.
Assigned Interventions: Pulmonary rehabilitation program (PRP) was conducted according to the
      guidelines of the American Thoracic Society/European Respiratory Society (ATS/ERS). Physical
      training was conducted over 24 sessions supervised, three times a week. The program included
      aerobic training in treadmill (with 30 min load determined by the dyspnea sensation - 4 to 6
      on the modified Borg scale) and localized training for upper limbs with free weights or
      elastic bands (movements performed based on the proprioceptive neuromuscular facilitation
      diagonals, performed in two series, lasting two minutes each) and lower limbs (quadriceps and
      triceps sural) with free weights and/or in the bodybuilding station .

      Pulmonary function test: Spirometry will be performed before the PRP, and it will be in
      accordance with ATS/ERS standards in order to provide the level of pulmonary obstruction and
      severity of disease. The predicted values will be calculated with the equations derived from
      Brazilian population.

      Glittre-ADL Test: The patients will be instructed to complete five laps on the follow circuit
      as quickly as possible: from a sitting position, the subject stands up and walks along a flat
      10-m long course, in the middle of which there is a two-step ladder (each step 17 cm high x
      27 cm deep) to be climbed; after completing the 10 m, the subject faces a shelf containing
      three 1-kg objects positioned on the top shelf (shoulder height) and moves them one by one to
      the bottom shelf (waist height) and then to the floor; the objects are then returned to the
      bottom shelf and finally to the top shelf again; the subject walks back, climbing up and down
      the steps, until reaching the starting point (chair), sits down and immediately begins the
      next lap. The subjects carry a weighted backpack (2.5 kg for women, 5.0 kg for men). Two
      Glittre-ADL Tests will be conducted before and after the PRP.

      Six minute walk test (6MWT): The patients will be instructed to walk in order to perform the
      largest distance during six minutes. The walking speed will be selected by the patient,
      according to the guidelines of the ATS. Two 6MWTs will be conducted before and after the PRP.

      London Chest Activity of Daily Living scale: Patients will be asked about their perception of
      limitation in activities of daily living, using the London Chest Activity of Daily Living
      scale (LCADL) before and after the PRP.

      Modified Medical Research Council scale: Patients will be asked about their perception of
      dyspnea, using the modified Medical Research Council scale before and after the PRP.

      Saint George Respiratory Questionnaire: Patients will be asked about their perception of
      health-related quality of life, using the Saint George Respiratory Questionnaire before and
      after the PRP.

      COPD Assessment Test (CAT): Patients will be asked about their perception of the impact of
      COPD (cough, sputum, dyspnea, and chest tightness) on health status, using CAT before and
      after the PRP.
allocation: N/A
intervention model: Single Group Assignment
primary purpose: Treatment
masking: None (Open Label)
measure: Glittre ADL-Test
time frame: The change in the Glittre ADL-test performance from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).
description: Change in Glittre ADL-Test performance
measure: London Chest Activity of Daily Living
time frame: The change in the London Chest Activity of Daily Living score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).
description: Change in London Chest Activity of Daily Living score
measure: Six-minute walking test
time frame: The change in the distance walked during the six-minute walking test from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).
description: Change in six-minute walking test performance
measure: Modified Medical Research Council
time frame: The change in the Modified Medical Research Council score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).
description: Change in Modified Medical Research Council score
measure: COPD Assessment Test (CAT)
time frame: The change in the COPD Assessment Test (CAT) score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).
description: Change in COPD Assessment Test (CAT) score
measure: Saint George Respiratory Questionnaire (SGRQ)
time frame: The change in the Saint George Respiratory Questionnaire (SGRQ) score from baseline up to 24 pulmonary rehabilitation session (8 weeks of pulmonary rehabilitation).
description: Change in Saint George Respiratory Questionnaire (SGRQ) score
arm group label: Pulmonary Rehabilitation
arm group type: Experimental
description: Pulmonary Rehabilitation
intervention type: Other
intervention name: Pulmonary Rehabilitation
description: Pulmonary rehabilitation program (PRP) was conducted according to the guidelines of the American Thoracic Society/European Respiratory Society (Nici et al., 2006; Spruit et al., 2013). Physical training was conducted over 24 sessions supervised, three times a week. The program included aerobic training in treadmill (with 30 min load determined by the dyspnea sensation - 4 to 6 on the modified Borg scale) and localized training for upper limbs with free weights or elastic bands (movements performed based on the proprioceptive neuromuscular facilitation diagonals, performed in two series, lasting two minutes each) and lower limbs (quadriceps and triceps sural) with free weights and/or in the bodybuilding station.
arm group label: Pulmonary Rehabilitation
criteria: 
gender: All
minimum age: 40 Years
maximum age: 80 Years
healthy volunteers: No
last name: Anamaria F Mayer, PhD
role: Principal Investigator
affiliation: University of the State of Santa Catarina
facility: 
facility: 
country: Brazil
citation: Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, Carone M, Celli B, Engelen M, Fahy B, Garvey C, Goldstein R, Gosselink R, Lareau S, MacIntyre N, Maltais F, Morgan M, O'Donnell D, Prefault C, Reardon J, Rochester C, Schols A, Singh S, Troosters T; ATS/ERS Pulmonary Rehabilitation Writing Committee. American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. Am J Respir Crit Care Med. 2006 Jun 15;173(12):1390-413. doi: 10.1164/rccm.200508-1211ST. No abstract available.
PMID: 16760357
citation: Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, Hill K, Holland AE, Lareau SC, Man WD, Pitta F, Sewell L, Raskin J, Bourbeau J, Crouch R, Franssen FM, Casaburi R, Vercoulen JH, Vogiatzis I, Gosselink R, Clini EM, Effing TW, Maltais F, van der Palen J, Troosters T, Janssen DJ, Collins E, Garcia-Aymerich J, Brooks D, Fahy BF, Puhan MA, Hoogendoorn M, Garrod R, Schols AM, Carlin B, Benzo R, Meek P, Morgan M, Rutten-van Molken MP, Ries AL, Make B, Goldstein RS, Dowson CA, Brozek JL, Donner CF, Wouters EF; ATS/ERS Task Force on Pulmonary Rehabilitation. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med. 2013 Oct 15;188(8):e13-64. doi: 10.1164/rccm.201309-1634ST. Erratum In: Am J Respir Crit Care Med. 2014 Jun 15;189(12):1570.
PMID: 24127811
citation: Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J; ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J. 2005 Aug;26(2):319-38. doi: 10.1183/09031936.05.00034805. No abstract available.
PMID: 16055882
citation: Garrod R, Bestall JC, Paul EA, Wedzicha JA, Jones PW. Development and validation of a standardized measure of activity of daily living in patients with severe COPD: the London Chest Activity of Daily Living scale (LCADL). Respir Med. 2000 Jun;94(6):589-96. doi: 10.1053/rmed.2000.0786.
PMID: 10921765
citation: Carpes MF, Mayer AF, Simon KM, Jardim JR, Garrod R. The Brazilian Portuguese version of the London Chest Activity of Daily Living scale for use in patients with chronic obstructive pulmonary disease. J Bras Pneumol. 2008 Mar;34(3):143-51. doi: 10.1590/s1806-37132008000300004. English, Portuguese.
PMID: 18392462
citation: Kovelis D, Segretti NO, Probst VS, Lareau SC, Brunetto AF, Pitta F. Validation of the Modified Pulmonary Functional Status and Dyspnea Questionnaire and the Medical Research Council scale for use in Brazilian patients with chronic obstructive pulmonary disease. J Bras Pneumol. 2008 Dec;34(12):1008-18. doi: 10.1590/s1806-37132008001200005. English, Portuguese.
PMID: 19180335
citation: Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N. Development and first validation of the COPD Assessment Test. Eur Respir J. 2009 Sep;34(3):648-54. doi: 10.1183/09031936.00102509.
PMID: 19720809
citation: Holland AE, Spruit MA, Troosters T, Puhan MA, Pepin V, Saey D, McCormack MC, Carlin BW, Sciurba FC, Pitta F, Wanger J, MacIntyre N, Kaminsky DA, Culver BH, Revill SM, Hernandes NA, Andrianopoulos V, Camillo CA, Mitchell KE, Lee AL, Hill CJ, Singh SJ. An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease. Eur Respir J. 2014 Dec;44(6):1428-46. doi: 10.1183/09031936.00150314. Epub 2014 Oct 30.
PMID: 25359355
responsible party type: Principal Investigator
investigator affiliation: University of the State of Santa Catarina
investigator full name: Prof. Dra. Anamaria Fleig Mayer
investigator title: Principal Investigator
mesh term: Pulmonary Disease, Chronic Obstructive
sharing ipd: No