<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT03301142</url>
  </required_header>
  <id_info>
    <org_study_id>13341</org_study_id>
    <nct_id>NCT03301142</nct_id>
  </id_info>
  <brief_title>Study Comparing the Use of Laser and of Kinesiotherapy for the Treatment of Female Stress Urinary Incontinence</brief_title>
  <official_title>Randomized Trial Comparing the Use of Laser and of Kinesiotherapy for the Treatment of Female Stress Urinary Incontinence - a Pilot Study</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>University of Sao Paulo General Hospital</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>University of Sao Paulo General Hospital</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      The purpose of this study is compare the effect of laser and of kinesiotherapy in the&#xD;
      treatment of women with stress urinary incontinence&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      the objective of this project is to compare the effect of laser and of kinesiotherapy in the&#xD;
      treatment of women with stress urinary incontinence. A randomized controlled clinical trial&#xD;
      is proposed involving 40 women diagnosed with stress urinary incontinence randomized into two&#xD;
      groups: 1) treatment with application of Erbium Laser: YAG 2940nm, SMOOTH mode, one session&#xD;
      per month for three months (n=20); 2) treatment with kinesiotherapy for three months with&#xD;
      supervision twice a week (n=20). At baseline assessment, patients shall undergo anamnesis,&#xD;
      general physical and gynecological exam, assessments of the pelvic floor based on the&#xD;
      modified Oxford scale and of the presence of prolapse using the Pelvic Organ Prolapse&#xD;
      Quantification (POP-Q) system. The following exams shall also be performed: Type 1 urine,&#xD;
      urine culture, urodynamic study and 1-hour Pad test. Participants shall complete both the&#xD;
      King's Health Questionnaire and Incontinence Quality of Life Questionnaire (IQOL).&#xD;
      Post-treatment, patients will be assessed during follow-up visits at 1, 3, 6 and 12 months by&#xD;
      physical exam and application of the questionnaires. The Pad test will be re-administered at&#xD;
      6 and 12 months. Data will be grouped and statistically assessed.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Recruiting</last_known_status>
  <start_date type="Actual">August 2015</start_date>
  <completion_date type="Anticipated">July 2018</completion_date>
  <primary_completion_date type="Anticipated">February 2018</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>Single (Outcomes Assessor)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Improvement of urinary loss</measure>
    <time_frame>twelve months</time_frame>
    <description>the urinary loss will be evaluated with the pad test</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>improvement of pelvic floor strength</measure>
    <time_frame>twelve months</time_frame>
    <description>Functional evaluation of the pelvic floor with modified Oxford scale</description>
  </secondary_outcome>
  <other_outcome>
    <measure>impact in the quality of life</measure>
    <time_frame>twelve months</time_frame>
    <description>the impact in the quality of life will be evaluated with the quality of life questionnaires ( King's Health Questionnaire and IQOL quality of life questionnaires).</description>
  </other_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Anticipated">40</enrollment>
  <condition>Urinary Stress Incontinence</condition>
  <arm_group>
    <arm_group_label>Device laser</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>treatment with application of Erbium Laser: YAG 2940nm, SMOOTH mode, one session per month for three months (n=20</description>
  </arm_group>
  <arm_group>
    <arm_group_label>kinesiotherapy</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>with supervision twice a week for three months (n=20)</description>
  </arm_group>
  <intervention>
    <intervention_type>Procedure</intervention_type>
    <intervention_name>Laser</intervention_name>
    <description>The patients will be submitted to application of the Erbium Laser: YAG(yttrium aluminium garnet) 2940nm, SMOOTH mode developed by FOTONA.The vaginal canal will be accessed using a specific speculum. The 90 degree laser tip shall be used to perform 4 applications to the anterior and lateral vaginal wall at each of the 5 clock points (9,10:30,12,1:30,3 'o´-clock´), commencing at the back of the vagina, retracting in increments of 0.5cm, where 4 shots are made at each interval up to a distance 1cm short of the external opening of the urethra. After completion of this stage, the 90 degree tip shall be switched for the 360 degree tip, whereupon 4 additional applications shall be performed with 4 shots every 0.5 cm along the vaginal trajectory outlined above.</description>
    <arm_group_label>Device laser</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Procedure</intervention_type>
    <intervention_name>kinesiotherapy</intervention_name>
    <description>Patients will be guided by the physiotherapist to perform exercises to strengthen the pelvic floor muscles at home on a daily basis in the supine position with an empty bladder. It will be performed 10 repetitions of five-second contractions, the 15 three-second contractions; 20 two seconds contractions; 20 contractions of a second; 5 repetitions of strong contractions while coughing; 10 repetitions of exercise &quot;bridge&quot; associated with pelvic floor contraction and relaxation up in descending.The level of difficulty in performing the exercises will be determined in accordance with the adopted position. In .changes position should be held every four sessions.</description>
    <arm_group_label>kinesiotherapy</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Post-menopausal women with stress urinary incontinence will be recruited for this&#xD;
             study.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Patients presenting detrusor hyperactivity,stress urinary incontinence with sphincter&#xD;
             deficiency genital prolapse, stages 3 and 4 on the POP-Q system, genital cancer,&#xD;
             history of painful bladder syndrome, previous history of radiotherapy, keloid, use of&#xD;
             photosensitive drugs, uncontrolled diabetes mellitus, active vaginal infection&#xD;
             (bacterial vaginosis and candidiasis), abnormal genital bleeding or vaginal stenosis&#xD;
             shall be excluded.&#xD;
      </textblock>
    </criteria>
    <gender>Female</gender>
    <minimum_age>N/A</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>LUCILIA C FONSECA</last_name>
    <role>Principal Investigator</role>
    <affiliation>UNIVERSIDADE SÃO PAULO (USP)</affiliation>
  </overall_official>
  <overall_contact>
    <last_name>Lucilia C fonseca</last_name>
    <phone>5511981839348</phone>
    <email>LUCILIACFONSECA@GMAIL.COM</email>
  </overall_contact>
  <overall_contact_backup>
    <last_name>JORGE M HADDAD, PHD</last_name>
    <phone>5511930712843</phone>
    <email>JORGE_MILHEMH@UOL.COM.BR</email>
  </overall_contact_backup>
  <location>
    <facility>
      <name>Department of Gynecology and Obstetrics of the Clinicas Hospital of the (FMUSP).</name>
      <address>
        <city>São Paulo</city>
        <zip>05403-010</zip>
        <country>Brazil</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Lucilia C Fonseca, DR</last_name>
      <phone>5511981839348</phone>
      <email>luciliacfonseca@gmail.com</email>
    </contact>
    <investigator>
      <last_name>FERNANDA BA GIARRETA</last_name>
      <role>Sub-Investigator</role>
    </investigator>
    <investigator>
      <last_name>ELIZABETH A FERREIRA, PHD</last_name>
      <role>Sub-Investigator</role>
    </investigator>
    <investigator>
      <last_name>IVY NARDE, M</last_name>
      <role>Sub-Investigator</role>
    </investigator>
  </location>
  <location>
    <facility>
      <name>Department of Gynecology and Obstetrics of the Clinicas Hospital of the (FMUSP).</name>
      <address>
        <city>São Paulo</city>
        <zip>05403-010</zip>
        <country>Brazil</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Lucilia C Fonseca, DR</last_name>
      <phone>5511981839348</phone>
      <email>luciliacfonseca@gmail.com</email>
    </contact>
  </location>
  <location_countries>
    <country>Brazil</country>
  </location_countries>
  <results_reference>
    <citation>Abrams P, Blaivas JG, Stanton SL, Andersen JT. The standardisation of terminology of lower urinary tract function. The International Continence Society Committee on Standardisation of Terminology. Scand J Urol Nephrol Suppl. 1988;114:5-19. No abstract available.</citation>
    <PMID>3201169</PMID>
  </results_reference>
  <results_reference>
    <citation>Subak LL, Brown JS, Kraus SR, Brubaker L, Lin F, Richter HE, Bradley CS, Grady D; Diagnostic Aspects of Incontinence Study Group. The &quot;costs&quot; of urinary incontinence for women. Obstet Gynecol. 2006 Apr;107(4):908-16. doi: 10.1097/01.AOG.0000206213.48334.09.</citation>
    <PMID>16582131</PMID>
  </results_reference>
  <results_reference>
    <citation>Rovner ES, Wein AJ. Treatment options for stress urinary incontinence. Rev Urol. 2004;6 Suppl 3(Suppl 3):S29-47.</citation>
    <PMID>16985862</PMID>
  </results_reference>
  <results_reference>
    <citation>Herbison GP, Dean N. Weighted vaginal cones for urinary incontinence. Cochrane Database Syst Rev. 2013 Jul 8;2013(7):CD002114. doi: 10.1002/14651858.CD002114.pub2.</citation>
    <PMID>23836411</PMID>
  </results_reference>
  <results_reference>
    <citation>Gilpin SA, Gosling JA, Smith AR, Warrell DW. The pathogenesis of genitourinary prolapse and stress incontinence of urine. A histological and histochemical study. Br J Obstet Gynaecol. 1989 Jan;96(1):15-23. doi: 10.1111/j.1471-0528.1989.tb01570.x.</citation>
    <PMID>2923839</PMID>
  </results_reference>
  <results_reference>
    <citation>Falconer C, Ekman G, Malmstrom A, Ulmsten U. Decreased collagen synthesis in stress-incontinent women. Obstet Gynecol. 1994 Oct;84(4):583-6.</citation>
    <PMID>8090397</PMID>
  </results_reference>
  <results_reference>
    <citation>Konstantinos H, Eleni K, Dimitrios H. Dilemmas in the management of female stress incontinence: the role of pelvic floor muscle training. Int Urol Nephrol. 2006;38(3-4):513-25. doi: 10.1007/s11255-006-0085-3. Epub 2006 Nov 29.</citation>
    <PMID>17136582</PMID>
  </results_reference>
  <results_reference>
    <citation>Mouritsen L, Schiotz HA. Pro et contra pelvic floor exercises for female stress urinary incontinence. Acta Obstet Gynecol Scand. 2000 Dec;79(12):1043-5.</citation>
    <PMID>11130084</PMID>
  </results_reference>
  <results_reference>
    <citation>Fistonic N, Fistonic I, Gustek SF, Turina IS, Marton I, Vizintin Z, Kazic M, Hreljac I, Perhavec T, Lukac M. Minimally invasive, non-ablative Er:YAG laser treatment of stress urinary incontinence in women--a pilot study. Lasers Med Sci. 2016 May;31(4):635-43. doi: 10.1007/s10103-016-1884-0. Epub 2016 Feb 9.</citation>
    <PMID>26861984</PMID>
  </results_reference>
  <results_reference>
    <citation>Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M. Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg. 2005 Mar;31(3):334-40. doi: 10.1111/j.1524-4725.2005.31086.</citation>
    <PMID>15841638</PMID>
  </results_reference>
  <results_reference>
    <citation>Bump RC, Mattiasson A, Bo K, Brubaker LP, DeLancey JO, Klarskov P, Shull BL, Smith AR. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol. 1996 Jul;175(1):10-7. doi: 10.1016/s0002-9378(96)70243-0.</citation>
    <PMID>8694033</PMID>
  </results_reference>
  <results_reference>
    <citation>Rodrigues AM, de Oliveira LM, Martins Kde F, Del Roy CA, Sartori MG, Girao MJ, Castro Rde A. [Risk factors for genital prolapse in a Brazilian population]. Rev Bras Ginecol Obstet. 2009 Jan;31(1):17-21. doi: 10.1590/s0100-72032009000100004. Portuguese.</citation>
    <PMID>19347224</PMID>
  </results_reference>
  <results_reference>
    <citation>Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, Van Kerrebroeck P, Victor A, Wein A; Standardisation Sub-Committee of the International Continence Society. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Urology. 2003 Jan;61(1):37-49. doi: 10.1016/s0090-4295(02)02243-4. No abstract available.</citation>
    <PMID>12559262</PMID>
  </results_reference>
  <results_reference>
    <citation>Tamanini JT, D'Ancona CA, Botega NJ, Rodrigues Netto N Jr. [Validation of the Portuguese version of the King's Health Questionnaire for urinary incontinent women]. Rev Saude Publica. 2003 Apr;37(2):203-11. doi: 10.1590/s0034-89102003000200007. Epub 2003 Apr 4. Portuguese.</citation>
    <PMID>12700842</PMID>
  </results_reference>
  <results_reference>
    <citation>Souza CC, Rodrigues AM, Ferreira CE, Fonseca ES, di Bella ZI, Girao MJ, Sartori MG, Castro RA. Portuguese validation of the Urinary Incontinence-Specific Quality-of-Life Instrument: I-QOL. Int Urogynecol J Pelvic Floor Dysfunct. 2009 Oct;20(10):1183-9. doi: 10.1007/s00192-009-0916-8. Epub 2009 Jun 9.</citation>
    <PMID>19506791</PMID>
  </results_reference>
  <verification_date>November 2017</verification_date>
  <study_first_submitted>August 10, 2016</study_first_submitted>
  <study_first_submitted_qc>September 27, 2017</study_first_submitted_qc>
  <study_first_posted type="Actual">October 4, 2017</study_first_posted>
  <last_update_submitted>November 3, 2017</last_update_submitted>
  <last_update_submitted_qc>November 3, 2017</last_update_submitted_qc>
  <last_update_posted type="Actual">November 7, 2017</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>University of Sao Paulo General Hospital</investigator_affiliation>
    <investigator_full_name>Lucilia Carvalho da Fonseca</investigator_full_name>
    <investigator_title>Principal investigator</investigator_title>
  </responsible_party>
  <keyword>urinary stress incontinence</keyword>
  <keyword>urinary incontinence,stress</keyword>
  <keyword>laser</keyword>
  <keyword>physiotherapy</keyword>
  <keyword>kinesiotherapy</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Urinary Incontinence</mesh_term>
    <mesh_term>Enuresis</mesh_term>
    <mesh_term>Urinary Incontinence, Stress</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT03301142
org study id: 13341
nct id: NCT03301142
lead sponsor: 
has dmc: Yes
The purpose of this study is compare the effect of laser and of kinesiotherapy in the
      treatment of women with stress urinary incontinence
the objective of this project is to compare the effect of laser and of kinesiotherapy in the
      treatment of women with stress urinary incontinence. A randomized controlled clinical trial
      is proposed involving 40 women diagnosed with stress urinary incontinence randomized into two
      groups: 1) treatment with application of Erbium Laser: YAG 2940nm, SMOOTH mode, one session
      per month for three months (n=20); 2) treatment with kinesiotherapy for three months with
      supervision twice a week (n=20). At baseline assessment, patients shall undergo anamnesis,
      general physical and gynecological exam, assessments of the pelvic floor based on the
      modified Oxford scale and of the presence of prolapse using the Pelvic Organ Prolapse
      Quantification (POP-Q) system. The following exams shall also be performed: Type 1 urine,
      urine culture, urodynamic study and 1-hour Pad test. Participants shall complete both the
      King's Health Questionnaire and Incontinence Quality of Life Questionnaire (IQOL).
      Post-treatment, patients will be assessed during follow-up visits at 1, 3, 6 and 12 months by
      physical exam and application of the questionnaires. The Pad test will be re-administered at
      6 and 12 months. Data will be grouped and statistically assessed.
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Treatment
masking: Single (Outcomes Assessor)
measure: Improvement of urinary loss
time frame: twelve months
description: the urinary loss will be evaluated with the pad test
measure: improvement of pelvic floor strength
time frame: twelve months
description: Functional evaluation of the pelvic floor with modified Oxford scale
measure: impact in the quality of life
time frame: twelve months
description: the impact in the quality of life will be evaluated with the quality of life questionnaires ( King's Health Questionnaire and IQOL quality of life questionnaires).
arm group label: Device laser
arm group type: Experimental
description: treatment with application of Erbium Laser: YAG 2940nm, SMOOTH mode, one session per month for three months (n=20
arm group label: kinesiotherapy
arm group type: Active Comparator
description: with supervision twice a week for three months (n=20)
intervention type: Procedure
intervention name: Laser
description: The patients will be submitted to application of the Erbium Laser: YAG(yttrium aluminium garnet) 2940nm, SMOOTH mode developed by FOTONA.The vaginal canal will be accessed using a specific speculum. The 90 degree laser tip shall be used to perform 4 applications to the anterior and lateral vaginal wall at each of the 5 clock points (9,10:30,12,1:30,3 'o´-clock´), commencing at the back of the vagina, retracting in increments of 0.5cm, where 4 shots are made at each interval up to a distance 1cm short of the external opening of the urethra. After completion of this stage, the 90 degree tip shall be switched for the 360 degree tip, whereupon 4 additional applications shall be performed with 4 shots every 0.5 cm along the vaginal trajectory outlined above.
arm group label: Device laser
intervention type: Procedure
intervention name: kinesiotherapy
description: Patients will be guided by the physiotherapist to perform exercises to strengthen the pelvic floor muscles at home on a daily basis in the supine position with an empty bladder. It will be performed 10 repetitions of five-second contractions, the 15 three-second contractions; 20 two seconds contractions; 20 contractions of a second; 5 repetitions of strong contractions while coughing; 10 repetitions of exercise "bridge" associated with pelvic floor contraction and relaxation up in descending.The level of difficulty in performing the exercises will be determined in accordance with the adopted position. In .changes position should be held every four sessions.
arm group label: kinesiotherapy
criteria: 
gender: Female
minimum age: N/A
maximum age: N/A
healthy volunteers: No
last name: LUCILIA C FONSECA
role: Principal Investigator
affiliation: UNIVERSIDADE SÃO PAULO (USP)
last name: Lucilia C fonseca
phone: 5511981839348
email: LUCILIACFONSECA@GMAIL.COM
last name: JORGE M HADDAD, PHD
phone: 5511930712843
email: JORGE_MILHEMH@UOL.COM.BR
facility: 
status: Recruiting
contact: 
investigator: 
investigator: 
investigator: 
facility: 
status: Recruiting
contact: 
country: Brazil
citation: Abrams P, Blaivas JG, Stanton SL, Andersen JT. The standardisation of terminology of lower urinary tract function. The International Continence Society Committee on Standardisation of Terminology. Scand J Urol Nephrol Suppl. 1988;114:5-19. No abstract available.
PMID: 3201169
citation: Subak LL, Brown JS, Kraus SR, Brubaker L, Lin F, Richter HE, Bradley CS, Grady D; Diagnostic Aspects of Incontinence Study Group. The "costs" of urinary incontinence for women. Obstet Gynecol. 2006 Apr;107(4):908-16. doi: 10.1097/01.AOG.0000206213.48334.09.
PMID: 16582131
citation: Rovner ES, Wein AJ. Treatment options for stress urinary incontinence. Rev Urol. 2004;6 Suppl 3(Suppl 3):S29-47.
PMID: 16985862
citation: Herbison GP, Dean N. Weighted vaginal cones for urinary incontinence. Cochrane Database Syst Rev. 2013 Jul 8;2013(7):CD002114. doi: 10.1002/14651858.CD002114.pub2.
PMID: 23836411
citation: Gilpin SA, Gosling JA, Smith AR, Warrell DW. The pathogenesis of genitourinary prolapse and stress incontinence of urine. A histological and histochemical study. Br J Obstet Gynaecol. 1989 Jan;96(1):15-23. doi: 10.1111/j.1471-0528.1989.tb01570.x.
PMID: 2923839
citation: Falconer C, Ekman G, Malmstrom A, Ulmsten U. Decreased collagen synthesis in stress-incontinent women. Obstet Gynecol. 1994 Oct;84(4):583-6.
PMID: 8090397
citation: Konstantinos H, Eleni K, Dimitrios H. Dilemmas in the management of female stress incontinence: the role of pelvic floor muscle training. Int Urol Nephrol. 2006;38(3-4):513-25. doi: 10.1007/s11255-006-0085-3. Epub 2006 Nov 29.
PMID: 17136582
citation: Mouritsen L, Schiotz HA. Pro et contra pelvic floor exercises for female stress urinary incontinence. Acta Obstet Gynecol Scand. 2000 Dec;79(12):1043-5.
PMID: 11130084
citation: Fistonic N, Fistonic I, Gustek SF, Turina IS, Marton I, Vizintin Z, Kazic M, Hreljac I, Perhavec T, Lukac M. Minimally invasive, non-ablative Er:YAG laser treatment of stress urinary incontinence in women--a pilot study. Lasers Med Sci. 2016 May;31(4):635-43. doi: 10.1007/s10103-016-1884-0. Epub 2016 Feb 9.
PMID: 26861984
citation: Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M. Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg. 2005 Mar;31(3):334-40. doi: 10.1111/j.1524-4725.2005.31086.
PMID: 15841638
citation: Bump RC, Mattiasson A, Bo K, Brubaker LP, DeLancey JO, Klarskov P, Shull BL, Smith AR. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol. 1996 Jul;175(1):10-7. doi: 10.1016/s0002-9378(96)70243-0.
PMID: 8694033
citation: Rodrigues AM, de Oliveira LM, Martins Kde F, Del Roy CA, Sartori MG, Girao MJ, Castro Rde A. [Risk factors for genital prolapse in a Brazilian population]. Rev Bras Ginecol Obstet. 2009 Jan;31(1):17-21. doi: 10.1590/s0100-72032009000100004. Portuguese.
PMID: 19347224
citation: Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, Van Kerrebroeck P, Victor A, Wein A; Standardisation Sub-Committee of the International Continence Society. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Urology. 2003 Jan;61(1):37-49. doi: 10.1016/s0090-4295(02)02243-4. No abstract available.
PMID: 12559262
citation: Tamanini JT, D'Ancona CA, Botega NJ, Rodrigues Netto N Jr. [Validation of the Portuguese version of the King's Health Questionnaire for urinary incontinent women]. Rev Saude Publica. 2003 Apr;37(2):203-11. doi: 10.1590/s0034-89102003000200007. Epub 2003 Apr 4. Portuguese.
PMID: 12700842
citation: Souza CC, Rodrigues AM, Ferreira CE, Fonseca ES, di Bella ZI, Girao MJ, Sartori MG, Castro RA. Portuguese validation of the Urinary Incontinence-Specific Quality-of-Life Instrument: I-QOL. Int Urogynecol J Pelvic Floor Dysfunct. 2009 Oct;20(10):1183-9. doi: 10.1007/s00192-009-0916-8. Epub 2009 Jun 9.
PMID: 19506791
responsible party type: Principal Investigator
investigator affiliation: University of Sao Paulo General Hospital
investigator full name: Lucilia Carvalho da Fonseca
investigator title: Principal investigator
mesh term: Urinary Incontinence
mesh term: Enuresis
mesh term: Urinary Incontinence, Stress
sharing ipd: No