<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT02979236</url>
  </required_header>
  <id_info>
    <org_study_id>CH2016-01</org_study_id>
    <nct_id>NCT02979236</nct_id>
  </id_info>
  <brief_title>Italian Multi-center Registry of Self-apposing Coronary Stent in Patients With STEMI</brief_title>
  <acronym>iPOSITION</acronym>
  <official_title>Prospective, Observational, Italian Multi-center Registry of Self-aPposing cOronary Stent in Patients Presenting With ST-segment Elevation Myocardial InfarcTION: the iPOSITION Registry</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>UOSD Emodinamica Diagnostica e Interventistica</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>UOSD Emodinamica Diagnostica e Interventistica</source>
  <brief_summary>
    <textblock>
      The aim of this registry is to collect clinical data on nitinol self-expanding STENTYS&#xD;
      Xposition S™ in order to evaluate the efficacy and safety in patients presenting with ST&#xD;
      segment elevation myocardial infarction&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Recruiting</last_known_status>
  <start_date>June 2016</start_date>
  <primary_completion_date type="Anticipated">December 2018</primary_completion_date>
  <study_type>Observational</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <observational_model>Cohort</observational_model>
    <time_perspective>Prospective</time_perspective>
  </study_design_info>
  <primary_outcome>
    <measure>Target Lesion Failure (TLF)</measure>
    <time_frame>12 months post procedure</time_frame>
    <description>target lesion failure will be assessed as the composite of cardiac death; recurrent Target Vessel-Related Myocardial Infarction (MI) and clinically driven Target Lesion Revascularization (TLR) by percutaneous or surgical methods (CABG).</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Procedural success without the occurrence of death and repeat ischemia-driven revascularization of the target lesion during the hospital stay</measure>
    <time_frame>during the hospitalization, an average of 6 days</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Target lesion failure at 30-day post-procedure</measure>
    <time_frame>30 day post procedure</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Death from any cause</measure>
    <time_frame>12 months post procedure</time_frame>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Stent thrombosis rate at 30-day and 12-months after the procedure</measure>
    <time_frame>30 days post procedure and 12 months post procedure</time_frame>
  </secondary_outcome>
  <number_of_groups>1</number_of_groups>
  <enrollment type="Anticipated">250</enrollment>
  <condition>ST Segment Elevation Myocardial Infarction</condition>
  <arm_group>
    <arm_group_label>STEMI treated with STENTYS Xposition S</arm_group_label>
    <description>Patients 18 years of age and older presenting with symptoms consistent with a ST-Elevation Myocardial Infarction (STEMI) lasting ≤12 hrs in duration, with ≥2 mm of ST-segment elevation in ≥2 contiguous leads, treated with primary stent implantation (Xposition S planned per operator's assessment).</description>
  </arm_group>
  <intervention>
    <intervention_type>Device</intervention_type>
    <intervention_name>STENTYS Xposition S</intervention_name>
    <arm_group_label>STEMI treated with STENTYS Xposition S</arm_group_label>
  </intervention>
  <eligibility>
    <study_pop>
      <textblock>
        Patients 18 years of age and older presenting with symptoms consistent with a ST-Elevation&#xD;
        Myocardial Infarction (STEMI) lasting ≤12 hrs in duration, with ≥2 mm of ST-segment&#xD;
        elevation in ≥2 contiguous leads, treated with primary stent implantation (Xposition S&#xD;
        planned per operator's assessment).&#xD;
      </textblock>
    </study_pop>
    <sampling_method>Non-Probability Sample</sampling_method>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Patients 18 years of age and older presenting with symptoms consistent with a&#xD;
             ST-Elevation Myocardial Infarction (STEMI) lasting ≤12 hrs in duration, with ≥2 mm of&#xD;
             ST-segment elevation in ≥2 contiguous leads, treated with primary stent implantation&#xD;
             (Xposition S planned per operator's assessment).&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Cardiogenic shock&#xD;
&#xD;
          -  Multiple lesions requiring stenting in the target vessel.&#xD;
&#xD;
          -  Highly calcified lesions or excessive tortuosity at target lesion site.&#xD;
&#xD;
          -  Intrastent pathology.&#xD;
&#xD;
          -  Subject unable to take or comply with dual antiplatelet therapy as recommended per&#xD;
             guidelines.&#xD;
&#xD;
          -  Female subjects of childbearing potential known to be pregnant.&#xD;
&#xD;
          -  Co-morbidities with life expectancy less than 1 year&#xD;
&#xD;
          -  Patient unable to provide written informed consent.&#xD;
&#xD;
          -  Known allergies to stent component.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Livio Giuliani, MD PhD</last_name>
    <role>Principal Investigator</role>
    <affiliation>UOSD Emodinamica Diagnostica e Interventistica</affiliation>
  </overall_official>
  <overall_contact>
    <last_name>Livio Giuliani, MD PhD</last_name>
    <phone>347360091</phone>
    <email>lvgiuliani@gmail.com</email>
  </overall_contact>
  <overall_contact_backup>
    <last_name>Serena Rossi, MD</last_name>
    <phone>3286721396</phone>
    <email>rossisere.rs@gmail.com</email>
  </overall_contact_backup>
  <location>
    <facility>
      <name>Dipartimento cardiotoracico e vascolare - S.S Emodinamica Azienda Ospedaliera Nazionale SS Antonio e Biagio e Cesare Arrigo.</name>
      <address>
        <city>Alessandria</city>
        <zip>15121</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Not yet recruiting</status>
    <contact>
      <last_name>Gioel Gabrio Secco, MD PhD</last_name>
      <email>gioel.gabrio.secco@gmail.com</email>
    </contact>
  </location>
  <location>
    <facility>
      <name>UOC Cardiologia- UTIC Ospedale Civile &quot;C. e G.Mazzoni&quot;</name>
      <address>
        <city>Ascoli Piceno</city>
        <zip>63100</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Not yet recruiting</status>
    <contact>
      <last_name>Pierfrancesco Grossi, MD</last_name>
      <email>p.f.grossi@tiscali.it</email>
    </contact>
  </location>
  <location>
    <facility>
      <name>UOSD Emodinamica Diagnostica e Interventistica Ospedale SS Annunziata</name>
      <address>
        <city>Chieti</city>
        <zip>66100</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Livio Giuliani, MD PhD</last_name>
      <phone>3473690091</phone>
      <email>lvgiuliani@gmail.com</email>
    </contact>
    <contact_backup>
      <last_name>Serena Rossi, MD</last_name>
      <phone>3286721396</phone>
      <email>rossisere.rs@gmail.com</email>
    </contact_backup>
  </location>
  <location>
    <facility>
      <name>UOC Terapia cardiologica intensiva ed interventistica Azienda Ospedaliera Universitaria G. Martino</name>
      <address>
        <city>Messina</city>
        <zip>98121</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Franco Saporito, MD</last_name>
      <email>fsaporito@unime.it</email>
    </contact>
  </location>
  <location>
    <facility>
      <name>UOC Cardiologia Emodinamica Ospedale San Salvatore - Centrale</name>
      <address>
        <city>Pesaro</city>
        <country>Italy</country>
      </address>
    </facility>
    <status>Not yet recruiting</status>
    <contact>
      <last_name>Rosario Alessandro Parisi, MD</last_name>
      <email>saroparisi@hotmail.it</email>
    </contact>
  </location>
  <location>
    <facility>
      <name>UOC UTIC e Cardiologia Interventistica Ospedale S. Spirito</name>
      <address>
        <city>Pescara</city>
        <zip>65121</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Not yet recruiting</status>
    <contact>
      <last_name>Leonardo Paloscia, MD</last_name>
      <email>leonardo.paloscia@auls.pe.it</email>
    </contact>
  </location>
  <location>
    <facility>
      <name>UOC Emodinamica Ospedale Umberto I</name>
      <address>
        <city>Siracusa</city>
        <zip>96100</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Marco Contarini, MD</last_name>
      <email>marcocontarini@gmail.com</email>
    </contact>
    <contact_backup>
      <last_name>Giorgio Sacchetta, MD</last_name>
      <email>giorgiosacchetta@gmail.com</email>
    </contact_backup>
  </location>
  <location>
    <facility>
      <name>S.S. Emodinamica Ospedale San Giovanni Bosco</name>
      <address>
        <city>Torino</city>
        <zip>10154</zip>
        <country>Italy</country>
      </address>
    </facility>
    <status>Not yet recruiting</status>
    <contact>
      <last_name>Roberto Garbo, MD</last_name>
      <email>r.garbo68@gmail.com</email>
    </contact>
    <contact_backup>
      <last_name>Fabrizio Ugo, MD</last_name>
      <email>ugo.fabrizio@tiscali.it</email>
    </contact_backup>
  </location>
  <location_countries>
    <country>Italy</country>
  </location_countries>
  <reference>
    <citation>Kim YS, Koo BK, Seo JB, Park KW, Suh JW, Lee HY, Park JS, Kang HJ, Cho YS, Chung WY, Chae IH, Choi DJ, Kim HS, Oh BH, Park YB. The incidence and predictors of postprocedural incomplete stent apposition after angiographically successful drug-eluting stent implantation. Catheter Cardiovasc Interv. 2009 Jul 1;74(1):58-63. doi: 10.1002/ccd.21961.</citation>
    <PMID>19360868</PMID>
  </reference>
  <reference>
    <citation>Gutierrez-Chico JL, Regar E, Nuesch E, Okamura T, Wykrzykowska J, di Mario C, Windecker S, van Es GA, Gobbens P, Juni P, Serruys PW. Delayed coverage in malapposed and side-branch struts with respect to well-apposed struts in drug-eluting stents: in vivo assessment with optical coherence tomography. Circulation. 2011 Aug 2;124(5):612-23. doi: 10.1161/CIRCULATIONAHA.110.014514. Epub 2011 Jul 18.</citation>
    <PMID>21768536</PMID>
  </reference>
  <reference>
    <citation>Foin N, Gutierrez-Chico JL, Nakatani S, Torii R, Bourantas CV, Sen S, Nijjer S, Petraco R, Kousera C, Ghione M, Onuma Y, Garcia-Garcia HM, Francis DP, Wong P, Di Mario C, Davies JE, Serruys PW. Incomplete stent apposition causes high shear flow disturbances and delay in neointimal coverage as a function of strut to wall detachment distance: implications for the management of incomplete stent apposition. Circ Cardiovasc Interv. 2014 Apr;7(2):180-9. doi: 10.1161/CIRCINTERVENTIONS.113.000931. Epub 2014 Mar 18.</citation>
    <PMID>24642998</PMID>
  </reference>
  <reference>
    <citation>Cook S, Eshtehardi P, Kalesan B, Raber L, Wenaweser P, Togni M, Moschovitis A, Vogel R, Seiler C, Eberli FR, Luscher T, Meier B, Juni P, Windecker S. Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation. Eur Heart J. 2012 Jun;33(11):1334-43. doi: 10.1093/eurheartj/ehr484. Epub 2012 Jan 26.</citation>
    <PMID>22285579</PMID>
  </reference>
  <reference>
    <citation>Nakano M, Yahagi K, Otsuka F, Sakakura K, Finn AV, Kutys R, Ladich E, Fowler DR, Joner M, Virmani R. Causes of early stent thrombosis in patients presenting with acute coronary syndrome: an ex vivo human autopsy study. J Am Coll Cardiol. 2014 Jun 17;63(23):2510-2520. doi: 10.1016/j.jacc.2014.02.607. Epub 2014 Apr 23.</citation>
    <PMID>24768883</PMID>
  </reference>
  <reference>
    <citation>Amoroso G, van Geuns RJ, Spaulding C, Manzo-Silberman S, Hauptmann KE, Spaargaren R, Garcia-Garcia HM, Serruys PW, Verheye S. Assessment of the safety and performance of the STENTYS self-expanding coronary stent in acute myocardial infarction: results from the APPOSITION I study. EuroIntervention. 2011 Aug;7(4):428-36. doi: 10.4244/EIJV7I4A71.</citation>
    <PMID>21764660</PMID>
  </reference>
  <reference>
    <citation>van Geuns RJ, Tamburino C, Fajadet J, Vrolix M, Witzenbichler B, Eeckhout E, Spaulding C, Reczuch K, La Manna A, Spaargaren R, Garcia-Garcia HM, Regar E, Capodanno D, Van Langenhove G, Verheye S. Self-expanding versus balloon-expandable stents in acute myocardial infarction: results from the APPOSITION II study: self-expanding stents in ST-segment elevation myocardial infarction. JACC Cardiovasc Interv. 2012 Dec;5(12):1209-19. doi: 10.1016/j.jcin.2012.08.016.</citation>
    <PMID>23257368</PMID>
  </reference>
  <reference>
    <citation>Koch KT, Grundeken MJ, Vos NS, IJsselmuiden AJ, van Geuns RJ, Wessely R, Dengler T, La Manna A, Silvain J, Montalescot G, Spaargaren R, Tijssen JG, Amoroso G. One-year clinical outcomes of the STENTYS Self-Apposing coronary stent in patients presenting with ST-segment elevation myocardial infarction: results from the APPOSITION III registry. EuroIntervention. 2015 Jul;11(3):264-71. doi: 10.4244/EIJY15M02_08.</citation>
    <PMID>25692610</PMID>
  </reference>
  <reference>
    <citation>van Geuns RJ, Yetgin T, La Manna A, Tamburino C, Souteyrand G, Motreff P, Koch KT, Vrolix M, IJsselmuiden A, Amoroso G, Berland J, Montalescot G, Teiger E, Christiansen EH, Spaargaren R, Wijns W. STENTYS Self-Apposing sirolimus-eluting stent in ST-segment elevation myocardial infarction: results from the randomised APPOSITION IV trial. EuroIntervention. 2016 Feb;11(11):e1267-74. doi: 10.4244/EIJV11I11A248.</citation>
    <PMID>26865444</PMID>
  </reference>
  <reference>
    <citation>Grundeken MJ, Lu H, Mehran R, Cutlip DE, Leon MB, Yeung A, Koch KT, Montalescot G, van Geuns RJ, Spaargaren R, Buchbinder M. APPOSITION V: STENTYS coronary stent system clinical trial in subjects with ST-segment elevation myocardial infarction--rationale and design. Am Heart J. 2014 Nov;168(5):652-60. doi: 10.1016/j.ahj.2014.07.011. Epub 2014 Jul 24.</citation>
    <PMID>25440792</PMID>
  </reference>
  <reference>
    <citation>Sianos G, Papafaklis MI, Serruys PW. Angiographic thrombus burden classification in patients with ST-segment elevation myocardial infarction treated with percutaneous coronary intervention. J Invasive Cardiol. 2010 Oct;22(10 Suppl B):6B-14B.</citation>
    <PMID>20947930</PMID>
  </reference>
  <verification_date>November 2016</verification_date>
  <study_first_submitted>November 24, 2016</study_first_submitted>
  <study_first_submitted_qc>November 28, 2016</study_first_submitted_qc>
  <study_first_posted type="Estimate">December 1, 2016</study_first_posted>
  <last_update_submitted>November 28, 2016</last_update_submitted>
  <last_update_submitted_qc>November 28, 2016</last_update_submitted_qc>
  <last_update_posted type="Estimate">December 1, 2016</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>UOSD Emodinamica Diagnostica e Interventistica</investigator_affiliation>
    <investigator_full_name>Livio Giuliani</investigator_full_name>
    <investigator_title>MD PhD</investigator_title>
  </responsible_party>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Myocardial Infarction</mesh_term>
    <mesh_term>ST Elevation Myocardial Infarction</mesh_term>
    <mesh_term>Infarction</mesh_term>
  </condition_browse>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT02979236
org study id: CH2016-01
nct id: NCT02979236
lead sponsor: 
The aim of this registry is to collect clinical data on nitinol self-expanding STENTYS
      Xposition S™ in order to evaluate the efficacy and safety in patients presenting with ST
      segment elevation myocardial infarction
observational model: Cohort
time perspective: Prospective
measure: Target Lesion Failure (TLF)
time frame: 12 months post procedure
description: target lesion failure will be assessed as the composite of cardiac death; recurrent Target Vessel-Related Myocardial Infarction (MI) and clinically driven Target Lesion Revascularization (TLR) by percutaneous or surgical methods (CABG).
measure: Procedural success without the occurrence of death and repeat ischemia-driven revascularization of the target lesion during the hospital stay
time frame: during the hospitalization, an average of 6 days
measure: Target lesion failure at 30-day post-procedure
time frame: 30 day post procedure
measure: Death from any cause
time frame: 12 months post procedure
measure: Stent thrombosis rate at 30-day and 12-months after the procedure
time frame: 30 days post procedure and 12 months post procedure
arm group label: STEMI treated with STENTYS Xposition S
description: Patients 18 years of age and older presenting with symptoms consistent with a ST-Elevation Myocardial Infarction (STEMI) lasting ≤12 hrs in duration, with ≥2 mm of ST-segment elevation in ≥2 contiguous leads, treated with primary stent implantation (Xposition S planned per operator's assessment).
intervention type: Device
intervention name: STENTYS Xposition S
arm group label: STEMI treated with STENTYS Xposition S
study pop: 
sampling method: Non-Probability Sample
criteria: 
gender: All
minimum age: 18 Years
maximum age: N/A
healthy volunteers: No
last name: Livio Giuliani, MD PhD
role: Principal Investigator
affiliation: UOSD Emodinamica Diagnostica e Interventistica
last name: Livio Giuliani, MD PhD
phone: 347360091
email: lvgiuliani@gmail.com
last name: Serena Rossi, MD
phone: 3286721396
email: rossisere.rs@gmail.com
facility: 
status: Not yet recruiting
contact: 
facility: 
status: Not yet recruiting
contact: 
facility: 
status: Recruiting
contact: 
contact backup: 
facility: 
status: Recruiting
contact: 
facility: 
status: Not yet recruiting
contact: 
facility: 
status: Not yet recruiting
contact: 
facility: 
status: Recruiting
contact: 
contact backup: 
facility: 
status: Not yet recruiting
contact: 
contact backup: 
country: Italy
citation: Kim YS, Koo BK, Seo JB, Park KW, Suh JW, Lee HY, Park JS, Kang HJ, Cho YS, Chung WY, Chae IH, Choi DJ, Kim HS, Oh BH, Park YB. The incidence and predictors of postprocedural incomplete stent apposition after angiographically successful drug-eluting stent implantation. Catheter Cardiovasc Interv. 2009 Jul 1;74(1):58-63. doi: 10.1002/ccd.21961.
PMID: 19360868
citation: Gutierrez-Chico JL, Regar E, Nuesch E, Okamura T, Wykrzykowska J, di Mario C, Windecker S, van Es GA, Gobbens P, Juni P, Serruys PW. Delayed coverage in malapposed and side-branch struts with respect to well-apposed struts in drug-eluting stents: in vivo assessment with optical coherence tomography. Circulation. 2011 Aug 2;124(5):612-23. doi: 10.1161/CIRCULATIONAHA.110.014514. Epub 2011 Jul 18.
PMID: 21768536
citation: Foin N, Gutierrez-Chico JL, Nakatani S, Torii R, Bourantas CV, Sen S, Nijjer S, Petraco R, Kousera C, Ghione M, Onuma Y, Garcia-Garcia HM, Francis DP, Wong P, Di Mario C, Davies JE, Serruys PW. Incomplete stent apposition causes high shear flow disturbances and delay in neointimal coverage as a function of strut to wall detachment distance: implications for the management of incomplete stent apposition. Circ Cardiovasc Interv. 2014 Apr;7(2):180-9. doi: 10.1161/CIRCINTERVENTIONS.113.000931. Epub 2014 Mar 18.
PMID: 24642998
citation: Cook S, Eshtehardi P, Kalesan B, Raber L, Wenaweser P, Togni M, Moschovitis A, Vogel R, Seiler C, Eberli FR, Luscher T, Meier B, Juni P, Windecker S. Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation. Eur Heart J. 2012 Jun;33(11):1334-43. doi: 10.1093/eurheartj/ehr484. Epub 2012 Jan 26.
PMID: 22285579
citation: Nakano M, Yahagi K, Otsuka F, Sakakura K, Finn AV, Kutys R, Ladich E, Fowler DR, Joner M, Virmani R. Causes of early stent thrombosis in patients presenting with acute coronary syndrome: an ex vivo human autopsy study. J Am Coll Cardiol. 2014 Jun 17;63(23):2510-2520. doi: 10.1016/j.jacc.2014.02.607. Epub 2014 Apr 23.
PMID: 24768883
citation: Amoroso G, van Geuns RJ, Spaulding C, Manzo-Silberman S, Hauptmann KE, Spaargaren R, Garcia-Garcia HM, Serruys PW, Verheye S. Assessment of the safety and performance of the STENTYS self-expanding coronary stent in acute myocardial infarction: results from the APPOSITION I study. EuroIntervention. 2011 Aug;7(4):428-36. doi: 10.4244/EIJV7I4A71.
PMID: 21764660
citation: van Geuns RJ, Tamburino C, Fajadet J, Vrolix M, Witzenbichler B, Eeckhout E, Spaulding C, Reczuch K, La Manna A, Spaargaren R, Garcia-Garcia HM, Regar E, Capodanno D, Van Langenhove G, Verheye S. Self-expanding versus balloon-expandable stents in acute myocardial infarction: results from the APPOSITION II study: self-expanding stents in ST-segment elevation myocardial infarction. JACC Cardiovasc Interv. 2012 Dec;5(12):1209-19. doi: 10.1016/j.jcin.2012.08.016.
PMID: 23257368
citation: Koch KT, Grundeken MJ, Vos NS, IJsselmuiden AJ, van Geuns RJ, Wessely R, Dengler T, La Manna A, Silvain J, Montalescot G, Spaargaren R, Tijssen JG, Amoroso G. One-year clinical outcomes of the STENTYS Self-Apposing coronary stent in patients presenting with ST-segment elevation myocardial infarction: results from the APPOSITION III registry. EuroIntervention. 2015 Jul;11(3):264-71. doi: 10.4244/EIJY15M02_08.
PMID: 25692610
citation: van Geuns RJ, Yetgin T, La Manna A, Tamburino C, Souteyrand G, Motreff P, Koch KT, Vrolix M, IJsselmuiden A, Amoroso G, Berland J, Montalescot G, Teiger E, Christiansen EH, Spaargaren R, Wijns W. STENTYS Self-Apposing sirolimus-eluting stent in ST-segment elevation myocardial infarction: results from the randomised APPOSITION IV trial. EuroIntervention. 2016 Feb;11(11):e1267-74. doi: 10.4244/EIJV11I11A248.
PMID: 26865444
citation: Grundeken MJ, Lu H, Mehran R, Cutlip DE, Leon MB, Yeung A, Koch KT, Montalescot G, van Geuns RJ, Spaargaren R, Buchbinder M. APPOSITION V: STENTYS coronary stent system clinical trial in subjects with ST-segment elevation myocardial infarction--rationale and design. Am Heart J. 2014 Nov;168(5):652-60. doi: 10.1016/j.ahj.2014.07.011. Epub 2014 Jul 24.
PMID: 25440792
citation: Sianos G, Papafaklis MI, Serruys PW. Angiographic thrombus burden classification in patients with ST-segment elevation myocardial infarction treated with percutaneous coronary intervention. J Invasive Cardiol. 2010 Oct;22(10 Suppl B):6B-14B.
PMID: 20947930
responsible party type: Principal Investigator
investigator affiliation: UOSD Emodinamica Diagnostica e Interventistica
investigator full name: Livio Giuliani
investigator title: MD PhD
mesh term: Myocardial Infarction
mesh term: ST Elevation Myocardial Infarction
mesh term: Infarction