<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT02969525</url>
  </required_header>
  <id_info>
    <org_study_id>PA0008</org_study_id>
    <secondary_id>2016-001103-23</secondary_id>
    <nct_id>NCT02969525</nct_id>
  </id_info>
  <brief_title>A Study to Evaluate the Dose Response Based on the Efficacy, Safety and Tolerability of Bimekizumab in Subjects With Active Psoriatic Arthritis Which is a Type of Inflammatory Arthritis</brief_title>
  <acronym>BE ACTIVE</acronym>
  <official_title>A Multicenter, Phase 2B, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study to Evaluate the Efficacy and Safety of Bimekizumab in Active Psoriatic Arthritis</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>UCB Biopharma S.P.R.L.</agency>
      <agency_class>Industry</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>UCB Pharma</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      This is a study to evaluate the dose response based on the efficacy, safety and tolerability&#xD;
      of bimekizumab in subjects with active psoriatic arthritis.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">October 2016</start_date>
  <completion_date type="Actual">July 2018</completion_date>
  <primary_completion_date type="Actual">November 2017</primary_completion_date>
  <phase>Phase 2</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>ACR50 (American College of Rheumatology 50% Improvement) Response at Week 12</measure>
    <time_frame>Week 12</time_frame>
    <description>The ACR50 response rate was based on 50% improvement relative to Baseline in the following measures:&#xD;
Tender Joint Count (TJC) based on 78 joints&#xD;
Swollen Joint Count (SJC) based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by Patient's Global Assessment of Disease Activity (PGADA)&#xD;
Disease activity as assessed by Physician's Global Assessment of Disease Activity (PhGADA)&#xD;
Pain as assessed by Patient's Assessment of Arthritis Pain (PtAAP)&#xD;
Physical function as assessed by Health Assessment Questionnaire - Disability Index (HAQ-DI)&#xD;
Acute phase response as assessed by high sensitivity C-reactive protein (hs CRP).</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>ACR20 (American College of Rheumatology 20% Improvement) Response at Week 12</measure>
    <time_frame>Week 12</time_frame>
    <description>The ACR20 response rate was based on 20% improvement relative to Baseline in the following measures:&#xD;
TJC based on 78 joints&#xD;
SJC based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by PGADA&#xD;
Disease activity as assessed by PhGADA&#xD;
Pain as assessed by PtAAP&#xD;
Physical function as assessed by HAQ-DI&#xD;
Acute phase response as assessed by hs CRP&#xD;
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>ACR70 (American College of Rheumatology 70% Improvement) Response at Week 12</measure>
    <time_frame>Week 12</time_frame>
    <description>The ACR70 response rate was based on 70% improvement relative to Baseline in the following measures:&#xD;
TJC based on 78 joints&#xD;
SJC based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by PGADA&#xD;
Disease activity as assessed by PhGADA&#xD;
Pain as assessed by PtAAP&#xD;
Physical function as assessed by HAQ-DI&#xD;
Acute phase response as assessed by hs CRP&#xD;
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>PASI90 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1</measure>
    <time_frame>Week 12</time_frame>
    <description>The PASI90 response assessments are based on at least 90% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).&#xD;
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>PASI75 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1</measure>
    <time_frame>Week 12</time_frame>
    <description>The PASI75 response assessments are based on at least 75% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).&#xD;
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Percentage of Participants With at Least One Adverse Event (AE) During the Study</measure>
    <time_frame>From Screening Period until the Safety Follow-Up Visit (up to Week 72)</time_frame>
    <description>An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Percentage of Participants With at Least One Serious Adverse Event (SAE) During the Study</measure>
    <time_frame>From Screening Period until the Safety Follow-Up Visit (up to Week 72)</time_frame>
    <description>A Serious Adverse Event (SAE) is any untoward medical occurrence that at any dose:&#xD;
Results in death&#xD;
Is life-threatening&#xD;
Requires in patient hospitalization or prolongation of existing hospitalization&#xD;
Is a congenital anomaly or birth defect&#xD;
Is an infection that requires treatment parenteral antibiotics&#xD;
Other important medical events which based on medical or scientific judgement may jeopardize the patients, or may require medical or surgical intervention to prevent any of the above.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Percentage of Participants Who Withdrew Due to an Adverse Event (AE) During the Study</measure>
    <time_frame>From Screening Period until the Safety Follow-Up Visit (up to Week 72)</time_frame>
    <description>An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Vital Signs During the Study (Diastolic Blood Pressure, Systolic Blood Pressure)</measure>
    <time_frame>Baseline, 30 min and 1 hour post dose, Week 1, Week 2, pre- and post dose for the following Weeks: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 and 44 and Week 48</time_frame>
    <description>Diastolic and systolic blood pressure were measured in millimeters of mercury (mmHg).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Vital Signs During the Study (Pulse Rate)</measure>
    <time_frame>Baseline, 30 min and 1 hour post dose, Week 1, Week 2, pre- and post dose for the following Weeks: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 and 44 and Week 48</time_frame>
    <description>Pulse rate was measured in beats per minute (beats/min).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Body Weight During the Study</measure>
    <time_frame>Baseline, Week 12, Week 24, Week 36 and Week 48</time_frame>
    <description>Body weight was measured in kilograms.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Electrocardiogram (ECG) Intervals During the Study (QTcB, QTcF, PR, QRS, QT, RR)</measure>
    <time_frame>Baseline, Week 12 and Week 48</time_frame>
    <description>Electrocardiogram (ECG) intervals (QTcB= QT interval corrected for heart rate (Bazett's formula); QTcF= QT interval corrected for heart rate (Fridericia's formula)) were measured in milliseconds.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Basophils, Eosinophils, Leukocytes, Lymphocytes, Monocytes, Neutrophils)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Basophils, eosinophils, leukocytes, lymphocytes, monocytes, neutrophils were measured in number of white blood cells per liter (10^9/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB) Concentration, Hemoglobin)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Erythrocytes mean corpuscular hemoglobin (HGB) concentration and hemoglobin were measured in grams per liter (g/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB))</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Erythrocytes mean corpuscular hemoglobin (HGB) was measured in picograms (pg).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Volume)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Erythrocytes mean corpuscular volume was measured in femtolitres (fL).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Erythrocytes was measured in number of red blood cells per liter (10^12/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Hematocrit)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Hematocrit was measured in volume percentage (%) of red blood cells in blood.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Hematology Parameters During the Study (Platelets)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Platelets was measured in number of platelets per liter (10^9/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Biochemistry Parameters During the Study (Alanine Aminotransferase, Alkaline Phosphatase, Aspartate Aminotransferase, Gamma Glutamyl Transferase, Lactate Dehydrogenase)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, gamma glutamyl transferase, lactate dehydrogenase were measured in units per liter (U/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Biochemistry Parameters During the Study (Albumin)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Albumin was measured in grams per liter (g/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Biochemistry Parameters During the Study (Bilirubin, Creatinine, Urate)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Bilirubin, creatinine, urate were measured in micromols per liter (μmol/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Biochemistry Parameters During the Study (Calcium, Chloride, Cholesterol, Glucose, Magnesium, Potassium, Sodium)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Calcium, chloride, cholesterol, glucose, magnesium, potassium, sodium were measured in millimoles per liter (mmol/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Biochemistry Parameters During the Study (Urea Nitrogen)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Urea nitrogen was measured in millimoles per liter (mmol/L).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Urinalysis Parameters During the Study (Erythrocytes, Leukocytes, Renal Epithelial Casts, Squamous Epithelial Cells, Transitional Epithelial Cells)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Erythrocytes, leukocytes, renal epithelial casts, squamous epithelial cells, transitional epithelial cells were measured in cells per high power field (cells/HPF).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Urinalysis Parameters During the Study (Hyaline Casts)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Hyaline casts was measured in cells per low power field (cells/LPF).</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Changes From Baseline in Urinalysis Parameters During the Study (pH)</measure>
    <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
    <description>Urine pH was measured on a pH scale.</description>
  </secondary_outcome>
  <number_of_arms>5</number_of_arms>
  <enrollment type="Actual">206</enrollment>
  <condition>Psoriatic Arthritis</condition>
  <arm_group>
    <arm_group_label>Placebo</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Subjects will receive for 12 Weeks Placebo and will then be re-randomized to Bimekizumab dosage regimen 2 or Bimekizumab dosage regimen 3 for 36 Weeks.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Bimekizumab dosage regimen 1</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Subjects will receive for 12 Weeks Bimekizumab dosage regimen 1 and will then be re-randomized to Bimekizumab dosage regimen 2 or Bimekizumab dosage regimen 3 for 36 Weeks.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Bimekizumab dosage regimen 2</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Subjects will receive for 48 Weeks Bimekizumab dosage regimen 2.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Bimekizumab dosage regimen 3</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Subjects will receive for 48 Weeks Bimekizumab dosage regimen 3.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Bimekizumab dosage regimen 4</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Subjects will receive for 12 Weeks Bimekizumab dosage regimen 4 and will then be re-randomized to Bimekizumab dosage regimen 2 for 36 Weeks.</description>
  </arm_group>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Placebo</intervention_name>
    <arm_group_label>Placebo</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Bimekizumab</intervention_name>
    <description>Bimekizumab in different dosage regimens.</description>
    <arm_group_label>Bimekizumab dosage regimen 1</arm_group_label>
    <arm_group_label>Bimekizumab dosage regimen 2</arm_group_label>
    <arm_group_label>Bimekizumab dosage regimen 3</arm_group_label>
    <arm_group_label>Bimekizumab dosage regimen 4</arm_group_label>
    <other_name>UCB4940</other_name>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Subject has a documented diagnosis of adult-onset PsA classified by Classification&#xD;
             Criteria for Psoriatic Arthritis (CASPAR) criteria with symptoms for at least 6 months&#xD;
             prior to Screening, with active psoriatic arthritis (PsA) at Baseline/Day 1, and must&#xD;
             have at Baseline tender joint count (TJC) &gt;=3 out of 78 and swollen joint count (SJC)&#xD;
             &gt;=3 out of 76&#xD;
&#xD;
          -  Subject must be rheumatoid factor and anti-cyclic citrullinated peptide (CCP)&#xD;
             antibodies negative&#xD;
&#xD;
          -  Subject must have active psoriatic lesion(s) and/or a documented history of psoriasis&#xD;
&#xD;
          -  Subjects who are regularly taking nonsteroidal anti-inflammatory drug (NSAIDs)/COX-2&#xD;
             inhibitors as part of their PsA therapy are required to be on a stable dose/dose&#xD;
             regimen for at least 14 days before Baseline&#xD;
&#xD;
          -  Subjects taking corticosteroids must be on an average daily dose of &lt;=10mg/day&#xD;
             prednisone or equivalent for at least 14 days before Baseline and should remain on a&#xD;
             stable dose through the Week 16 visit&#xD;
&#xD;
          -  Subjects taking methotrexate (MTX) (&lt;=25mg /week) are allowed to continue their&#xD;
             medication if started at least 12 weeks prior to Baseline, with a stable dose for at&#xD;
             least 8 weeks before randomization&#xD;
&#xD;
          -  Subjects taking leflunomide (LEF; &lt;=20mg/day or an average of 20mg/day if not dosed&#xD;
             daily) are allowed to continue their medication if started at least 3 months prior to&#xD;
             Baseline, with a stable dose for at least 8 weeks before randomization. Dose and&#xD;
             dosing schedule should remain stable up to Week 16&#xD;
&#xD;
          -  Subjects may be tumor necrosis factor (TNF) inhibitor naïve or may have received 1&#xD;
             prior TNF inhibitor. Subjects who have been on a TNF inhibitor previously must have:&#xD;
&#xD;
               1. experienced an inadequate response to previous treatment given for at least 3&#xD;
                  months&#xD;
&#xD;
               2. been intolerant to administration (eg, had a side-effect/adverse event (AE) that&#xD;
                  led to discontinuation)&#xD;
&#xD;
               3. lost access to TNF inhibitor for other reasons&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Subjects with any current sign or symptom that may indicate an active infection (with&#xD;
             the exception of the common cold) or has had an infection requiring systemic&#xD;
             antibiotics within 2 weeks of Baseline/Day 1&#xD;
&#xD;
          -  Subjects with a history of chronic or recurrent infections, or a serious or&#xD;
             life-threatening infection within the 6 months prior to the Baseline Visit&#xD;
&#xD;
          -  Subjects with concurrent acute or chronic viral hepatitis B or C or human&#xD;
             immunodeficiency virus (HIV) infection&#xD;
&#xD;
          -  Subjects with known history of or current clinically active infection with&#xD;
             Histoplasma, Coccidioides, Paracoccidioides, Pneumocystis, Blastomyces, or Aspergillus&#xD;
             or current active Candidiasis&#xD;
&#xD;
          -  Subjects receiving any live (includes attenuated) vaccination within the 8 weeks prior&#xD;
             to Baseline&#xD;
&#xD;
          -  Subjects with known tuberculosis (TB) infection, at high risk of acquiring TB&#xD;
             infection, with latent TB infection (LTBI), or current or history of nontuberculous&#xD;
             mycobacteria (NTMB) infection&#xD;
&#xD;
          -  Subjects with a diagnosis of inflammatory conditions other than psoriasis or psoriatic&#xD;
             arthritis&#xD;
&#xD;
          -  Subjects with concurrent malignancy or a history of malignancy during the past 5 years&#xD;
             will be excluded, with following exceptions that may be included:&#xD;
&#xD;
               1. &lt;= 3 excised or ablated basal cell carcinomas of the skin&#xD;
&#xD;
               2. One squamous cell carcinoma of the skin (stage T1 maximum) successfully excised,&#xD;
                  or ablated only (other treatments, ie, chemotherapy, do not apply), with no signs&#xD;
                  of recurrence or metastases for more than 2 years prior to Screening&#xD;
&#xD;
               3. Actinic keratosis (-es)&#xD;
&#xD;
               4. Squamous cell carcinoma-in-situ of the skin successfully excised, or ablated,&#xD;
                  more than 6 months prior to Screening&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>UCB Cares</last_name>
    <role>Study Director</role>
    <affiliation>+1 844 599 2273(UCB)</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Pa0008 007</name>
      <address>
        <city>San Diego</city>
        <state>California</state>
        <zip>92037</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 005</name>
      <address>
        <city>Aventura</city>
        <state>Florida</state>
        <zip>33180</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 003</name>
      <address>
        <city>Hagerstown</city>
        <state>Maryland</state>
        <zip>21740</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 011</name>
      <address>
        <city>Lansing</city>
        <state>Minnesota</state>
        <zip>48910</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 025</name>
      <address>
        <city>Lexington</city>
        <state>New York</state>
        <zip>40504</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 014</name>
      <address>
        <city>Portland</city>
        <state>Oregon</state>
        <zip>97239</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 001</name>
      <address>
        <city>Duncansville</city>
        <state>Pennsylvania</state>
        <zip>16635</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 012</name>
      <address>
        <city>Johnston</city>
        <state>Rhode Island</state>
        <zip>02919</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 004</name>
      <address>
        <city>Charleston</city>
        <state>South Carolina</state>
        <zip>29406-93</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 010</name>
      <address>
        <city>Jackson</city>
        <state>Tennessee</state>
        <zip>38305</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 006</name>
      <address>
        <city>Dallas</city>
        <state>Texas</state>
        <zip>75231</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 013</name>
      <address>
        <city>Mesquite</city>
        <state>Texas</state>
        <zip>75150</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 002</name>
      <address>
        <city>Seattle</city>
        <state>Washington</state>
        <zip>98122</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 205</name>
      <address>
        <city>Brno</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 207</name>
      <address>
        <city>Olomouc</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 210</name>
      <address>
        <city>Praha 11</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 202</name>
      <address>
        <city>Praha 2</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 201</name>
      <address>
        <city>Praha 4</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 209</name>
      <address>
        <city>Praha 4</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 203</name>
      <address>
        <city>Zlin</city>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 302</name>
      <address>
        <city>Cologne</city>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 309</name>
      <address>
        <city>Erlangen</city>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 304</name>
      <address>
        <city>Hamburg</city>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 301</name>
      <address>
        <city>Ratingen</city>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 403</name>
      <address>
        <city>Budakeszierdo</city>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 401</name>
      <address>
        <city>Veszprem</city>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 452</name>
      <address>
        <city>Bialystok</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 453</name>
      <address>
        <city>Elblag</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 456</name>
      <address>
        <city>Elblag</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 455</name>
      <address>
        <city>Krakow</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 451</name>
      <address>
        <city>Poznan</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 450</name>
      <address>
        <city>Torun</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 454</name>
      <address>
        <city>Warszawa</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 459</name>
      <address>
        <city>Warszawa</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 465</name>
      <address>
        <city>Wroclaw</city>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 604</name>
      <address>
        <city>Moscow</city>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 605</name>
      <address>
        <city>Moscow</city>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 607</name>
      <address>
        <city>Moscow</city>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 606</name>
      <address>
        <city>Saint Petersburg</city>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Pa0008 608</name>
      <address>
        <city>Saint Petersburg</city>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Czechia</country>
    <country>Germany</country>
    <country>Hungary</country>
    <country>Poland</country>
    <country>Russian Federation</country>
    <country>United States</country>
  </location_countries>
  <removed_countries>
    <country>Czech Republic</country>
  </removed_countries>
  <results_reference>
    <citation>Mease PJ, Asahina A, Gladman DD, Tanaka Y, Tillett W, Ink B, Assudani D, de la Loge C, Coarse J, Eells J, Gossec L. Effect of bimekizumab on symptoms and impact of disease in patients with psoriatic arthritis over 3 years: results from BE ACTIVE. Rheumatology (Oxford). 2023 Feb 1;62(2):617-628. doi: 10.1093/rheumatology/keac353.</citation>
    <PMID>35789257</PMID>
  </results_reference>
  <verification_date>March 2023</verification_date>
  <study_first_submitted>November 10, 2016</study_first_submitted>
  <study_first_submitted_qc>November 16, 2016</study_first_submitted_qc>
  <study_first_posted type="Estimate">November 21, 2016</study_first_posted>
  <results_first_submitted>October 30, 2020</results_first_submitted>
  <results_first_submitted_qc>October 30, 2020</results_first_submitted_qc>
  <results_first_posted type="Actual">November 25, 2020</results_first_posted>
  <disposition_first_submitted>November 2, 2018</disposition_first_submitted>
  <disposition_first_submitted_qc>November 2, 2018</disposition_first_submitted_qc>
  <disposition_first_posted type="Actual">November 6, 2018</disposition_first_posted>
  <last_update_submitted>March 17, 2023</last_update_submitted>
  <last_update_submitted_qc>March 17, 2023</last_update_submitted_qc>
  <last_update_posted type="Actual">March 20, 2023</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <keyword>Psoriatic Arthritis</keyword>
  <keyword>PsA</keyword>
  <keyword>Bimekizumab</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Arthritis</mesh_term>
    <mesh_term>Arthritis, Psoriatic</mesh_term>
  </condition_browse>
  <provided_document_section>
    <provided_document>
      <document_type>Study Protocol</document_type>
      <document_has_protocol>Yes</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>No</document_has_sap>
      <document_date>March 9, 2018</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/25/NCT02969525/Prot_000.pdf</document_url>
    </provided_document>
    <provided_document>
      <document_type>Statistical Analysis Plan</document_type>
      <document_has_protocol>No</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>Yes</document_has_sap>
      <document_date>September 7, 2018</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/25/NCT02969525/SAP_001.pdf</document_url>
    </provided_document>
  </provided_document_section>

  <clinical_results>

    <participant_flow>
      <recruitment_details>The study started to enroll patients in October 2016 and concluded in July 2018.</recruitment_details>
      <pre_assignment_details>The study included a 28-Day Screening Period, followed by a Double-blind Period from Day 1 to Week 12, prior to treatment re-randomization, a Dose-blind Period, from Week 12 after the treatment re-randomization and up to Week 48 and a Safety Follow-Up (SFU) Period, post week 48.&#xD;
The Participant Flow refers to the Randomized Set and Dose-Blind Set.</pre_assignment_details>
      <group_list>
        <group group_id="P1">
          <title>Placebo</title>
          <description>Participants received Placebo during the 12 Weeks Double-Blind Period.</description>
        </group>
        <group group_id="P2">
          <title>BKZ 16 mg</title>
          <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period.</description>
        </group>
        <group group_id="P3">
          <title>BKZ 160 mg</title>
          <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period.</description>
        </group>
        <group group_id="P4">
          <title>BKZ 160 mg LD</title>
          <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period.</description>
        </group>
        <group group_id="P5">
          <title>BKZ 320 mg</title>
          <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period.</description>
        </group>
        <group group_id="P6">
          <title>Placebo - BKZ 160 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Placebo were re-randomized to receive Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) for 36 weeks in the Dose-Blind Period.</description>
        </group>
        <group group_id="P7">
          <title>Placebo - BZK 320 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Placebo were re-randomized to receive Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) for 36 weeks in the Dose-Blind Period.</description>
        </group>
        <group group_id="P8">
          <title>BKZ 16 mg - BKZ 160 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Bimekizumab (BKZ) 16 mg every 4 weeks (Q4W) were re-randomized to receive BKZ 160 mg Q4W for 36 weeks in the Dose-Blind Period.</description>
        </group>
        <group group_id="P9">
          <title>BZK 16 mg - BZK 320 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Bimekizumab (BKZ) 16 mg every 4 weeks (Q4W) were re-randomized to receive BKZ 320 mg Q4W for 36 weeks in the Dose-Blind Period.</description>
        </group>
        <group group_id="P10">
          <title>BZK 160 mg LD - BZK 160 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) were re-randomized to receive BKZ 160 mg Q4W for 36 weeks in the Dose-Blind Period.</description>
        </group>
        <group group_id="P11">
          <title>BZK 160 mg - BKZ Dose 160 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) were re-randomized to receive BKZ 160 mg Q4W for 36 weeks in the Dose-Blind Period.</description>
        </group>
        <group group_id="P12">
          <title>BKZ 320 mg - BKZ 320 mg</title>
          <description>After the 12 Weeks Double-Blind Period participants randomized to Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) were re-randomized to receive BKZ 320 mg Q4W for 36 weeks in the Dose-Blind Period.</description>
        </group>
      </group_list>
      <period_list>
        <period>
          <title>Double-Blind Period</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="42"/>
                <participants group_id="P2" count="41"/>
                <participants group_id="P3" count="41"/>
                <participants group_id="P4" count="41"/>
                <participants group_id="P5" count="41"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>Completed Double-Blind Period</title>
              <participants_list>
                <participants group_id="P1" count="42"/>
                <participants group_id="P2" count="41"/>
                <participants group_id="P3" count="40"/>
                <participants group_id="P4" count="39"/>
                <participants group_id="P5" count="41"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>Completed Wk12 and Started Dose-Blind</title>
              <participants_list>
                <participants group_id="P1" count="40"/>
                <participants group_id="P2" count="41"/>
                <participants group_id="P3" count="40"/>
                <participants group_id="P4" count="37"/>
                <participants group_id="P5" count="41"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="40"/>
                <participants group_id="P2" count="41"/>
                <participants group_id="P3" count="40"/>
                <participants group_id="P4" count="37"/>
                <participants group_id="P5" count="41"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="2"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="1"/>
                <participants group_id="P4" count="4"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </milestone>
          </milestone_list>
          <drop_withdraw_reason_list>
            <drop_withdraw_reason>
              <title>Adverse Event</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="1"/>
                <participants group_id="P4" count="1"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>LOW EGFR</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="1"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Study medication discontinued prior Wk12</title>
              <participants_list>
                <participants group_id="P1" count="2"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="2"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
          </drop_withdraw_reason_list>
        </period>
        <period>
          <title>Dose-Blind Period</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="20"/>
                <participants group_id="P7" count="20"/>
                <participants group_id="P8" count="22"/>
                <participants group_id="P9" count="19"/>
                <participants group_id="P10" count="37"/>
                <participants group_id="P11" count="40"/>
                <participants group_id="P12" count="41"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="20"/>
                <participants group_id="P7" count="18"/>
                <participants group_id="P8" count="22"/>
                <participants group_id="P9" count="18"/>
                <participants group_id="P10" count="34"/>
                <participants group_id="P11" count="38"/>
                <participants group_id="P12" count="39"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="2"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="1"/>
                <participants group_id="P10" count="3"/>
                <participants group_id="P11" count="2"/>
                <participants group_id="P12" count="2"/>
              </participants_list>
            </milestone>
          </milestone_list>
          <drop_withdraw_reason_list>
            <drop_withdraw_reason>
              <title>Adverse Event</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="1"/>
                <participants group_id="P11" count="1"/>
                <participants group_id="P12" count="1"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Withdrawal by Subject</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="2"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="1"/>
                <participants group_id="P10" count="2"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Non-cooperating patient</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="1"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Withdrew before Safety Follow-up visit</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="1"/>
                <participants group_id="P12" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
          </drop_withdraw_reason_list>
        </period>
      </period_list>
    </participant_flow>

    <baseline>
      <population>The Baseline Characteristics refer to the Full Analysis Set (FAS), which consisted of all randomized study participants who received at least 1 dose of investigational medicinal product (IMP) and had a valid measurement of the primary efficacy variable at Baseline.</population>
      <group_list>
        <group group_id="B1">
          <title>Placebo</title>
          <description>Participants received Placebo during the 12 Weeks Double-Blind Period.</description>
        </group>
        <group group_id="B2">
          <title>BKZ 16 mg</title>
          <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period.</description>
        </group>
        <group group_id="B3">
          <title>BKZ 160 mg</title>
          <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period.</description>
        </group>
        <group group_id="B4">
          <title>BKZ 160 mg LD</title>
          <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period.</description>
        </group>
        <group group_id="B5">
          <title>BKZ 320 mg</title>
          <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period.</description>
        </group>
        <group group_id="B6">
          <title>Total Title</title>
        </group>
      </group_list>
      <analyzed_list>
        <analyzed>
          <units>Participants</units>
          <scope>Overall</scope>
          <count_list>
            <count group_id="B1" value="42"/>
            <count group_id="B2" value="41"/>
            <count group_id="B3" value="41"/>
            <count group_id="B4" value="41"/>
            <count group_id="B5" value="41"/>
            <count group_id="B6" value="206"/>
          </count_list>
        </analyzed>
      </analyzed_list>
      <measure_list>
        <measure>
          <title>Age</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <category_list>
                <category>
                  <title>&lt;=18 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Between 18 and 65 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="38"/>
                    <measurement group_id="B2" value="35"/>
                    <measurement group_id="B3" value="40"/>
                    <measurement group_id="B4" value="36"/>
                    <measurement group_id="B5" value="36"/>
                    <measurement group_id="B6" value="185"/>
                  </measurement_list>
                </category>
                <category>
                  <title>&gt;=65 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="4"/>
                    <measurement group_id="B2" value="6"/>
                    <measurement group_id="B3" value="1"/>
                    <measurement group_id="B4" value="5"/>
                    <measurement group_id="B5" value="5"/>
                    <measurement group_id="B6" value="21"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Age</title>
          <units>years</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="49.02" spread="12.07"/>
                    <measurement group_id="B2" value="49.98" spread="13.56"/>
                    <measurement group_id="B3" value="48.00" spread="11.65"/>
                    <measurement group_id="B4" value="49.05" spread="12.99"/>
                    <measurement group_id="B5" value="50.39" spread="12.08"/>
                    <measurement group_id="B6" value="49.29" spread="12.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Sex: Female, Male</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <category_list>
                <category>
                  <title>Female</title>
                  <measurement_list>
                    <measurement group_id="B1" value="18"/>
                    <measurement group_id="B2" value="17"/>
                    <measurement group_id="B3" value="21"/>
                    <measurement group_id="B4" value="27"/>
                    <measurement group_id="B5" value="18"/>
                    <measurement group_id="B6" value="101"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Male</title>
                  <measurement_list>
                    <measurement group_id="B1" value="24"/>
                    <measurement group_id="B2" value="24"/>
                    <measurement group_id="B3" value="20"/>
                    <measurement group_id="B4" value="14"/>
                    <measurement group_id="B5" value="23"/>
                    <measurement group_id="B6" value="105"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Race/Ethnicity, Customized</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <category_list>
                <category>
                  <title>Asian</title>
                  <measurement_list>
                    <measurement group_id="B1" value="1"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="1"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Black</title>
                  <measurement_list>
                    <measurement group_id="B1" value="1"/>
                    <measurement group_id="B2" value="1"/>
                    <measurement group_id="B3" value="2"/>
                    <measurement group_id="B4" value="1"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="5"/>
                  </measurement_list>
                </category>
                <category>
                  <title>White</title>
                  <measurement_list>
                    <measurement group_id="B1" value="40"/>
                    <measurement group_id="B2" value="40"/>
                    <measurement group_id="B3" value="39"/>
                    <measurement group_id="B4" value="40"/>
                    <measurement group_id="B5" value="41"/>
                    <measurement group_id="B6" value="200"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </measure_list>
    </baseline>

    <outcome_list>
      <outcome>
        <type>Primary</type>
        <title>ACR50 (American College of Rheumatology 50% Improvement) Response at Week 12</title>
        <description>The ACR50 response rate was based on 50% improvement relative to Baseline in the following measures:&#xD;
Tender Joint Count (TJC) based on 78 joints&#xD;
Swollen Joint Count (SJC) based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by Patient's Global Assessment of Disease Activity (PGADA)&#xD;
Disease activity as assessed by Physician's Global Assessment of Disease Activity (PhGADA)&#xD;
Pain as assessed by Patient's Assessment of Arthritis Pain (PtAAP)&#xD;
Physical function as assessed by Health Assessment Questionnaire - Disability Index (HAQ-DI)&#xD;
Acute phase response as assessed by high sensitivity C-reactive protein (hs CRP).</description>
        <time_frame>Week 12</time_frame>
        <population>The Full Analysis Set (FAS) consisted of all randomized study participants who received at least 1 dose of investigational medicinal product (IMP) and had a valid measurement of the primary efficacy variable at Baseline.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (FAS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
        </group_list>
        <measure>
          <title>ACR50 (American College of Rheumatology 50% Improvement) Response at Week 12</title>
          <description>The ACR50 response rate was based on 50% improvement relative to Baseline in the following measures:&#xD;
Tender Joint Count (TJC) based on 78 joints&#xD;
Swollen Joint Count (SJC) based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by Patient's Global Assessment of Disease Activity (PGADA)&#xD;
Disease activity as assessed by Physician's Global Assessment of Disease Activity (PhGADA)&#xD;
Pain as assessed by Patient's Assessment of Arthritis Pain (PtAAP)&#xD;
Physical function as assessed by Health Assessment Questionnaire - Disability Index (HAQ-DI)&#xD;
Acute phase response as assessed by high sensitivity C-reactive protein (hs CRP).</description>
          <population>The Full Analysis Set (FAS) consisted of all randomized study participants who received at least 1 dose of investigational medicinal product (IMP) and had a valid measurement of the primary efficacy variable at Baseline.</population>
          <units>percentage of subjects</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="41"/>
                <count group_id="O3" value="41"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.1"/>
                    <measurement group_id="O2" value="26.8"/>
                    <measurement group_id="O3" value="41.5"/>
                    <measurement group_id="O4" value="46.3"/>
                    <measurement group_id="O5" value="24.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
              <group_id>O3</group_id>
              <group_id>O4</group_id>
              <group_id>O5</group_id>
            </group_id_list>
            <groups_desc>Statistic and p-value were calculated using a Cochran-Mantel-Haenszel test (test for non-zero correlation statistic) based on modified ridit scores and including geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure as stratification factors.&#xD;
The 160 loading dose arm was not considered in the dose-response because this is a mixed dose and the test is examining linear dose response.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.031</p_value>
            <method>Cochran-Mantel-Haenszel</method>
            <param_type>Correlation statistic</param_type>
            <param_value>4.6</param_value>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Factor Necrosis (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <non_inferiority_desc>The pairwise testing of each bimekizumab dose versus placebo accounted for multiplicity by using a fixed sequence testing procedure with each bimekizumab dose being tested sequentially from the highest dose to the lowest dose. If the sequential testing failed to reach significance at a significance level of alpha=0.05, then the pairwise testing continued and the comparison was seen as non-significant.</non_inferiority_desc>
            <p_value>=0.032</p_value>
            <p_value_desc>The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>4.2</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>1.13</ci_lower_limit>
            <ci_upper_limit>15.23</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O3</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Factor Necrosis (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <non_inferiority_desc>The pairwise testing of each bimekizumab dose versus placebo accounted for multiplicity by using a fixed sequence testing procedure with each bimekizumab dose being tested sequentially from the highest dose to the lowest dose. If the sequential testing failed to reach significance at a significance level of alpha=0.05, then the pairwise testing continued and the comparison was seen as non-significant.</non_inferiority_desc>
            <p_value>=0.001</p_value>
            <p_value_desc>The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>8.1</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>2.28</ci_lower_limit>
            <ci_upper_limit>28.74</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O4</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Factor Necrosis (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <non_inferiority_desc>The pairwise testing of each bimekizumab dose versus placebo accounted for multiplicity by using a fixed sequence testing procedure with each bimekizumab dose being tested sequentially from the highest dose to the lowest dose. If the sequential testing failed to reach significance at a significance level of alpha=0.05, then the pairwise testing continued and the comparison was seen as non-significant.</non_inferiority_desc>
            <p_value>&lt;0.001</p_value>
            <p_value_desc>The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>9.7</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>2.73</ci_lower_limit>
            <ci_upper_limit>34.26</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O5</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Factor Necrosis (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <non_inferiority_desc>The pairwise testing of each bimekizumab dose versus placebo accounted for multiplicity by using a fixed sequence testing procedure with each bimekizumab dose being tested sequentially from the highest dose to the lowest dose. If the sequential testing failed to reach significance at a significance level of alpha=0.05, then the pairwise testing continued and the comparison was seen as non-significant.</non_inferiority_desc>
            <p_value>=0.051</p_value>
            <p_value_desc>The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>3.7</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>1.00</ci_lower_limit>
            <ci_upper_limit>13.68</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>ACR20 (American College of Rheumatology 20% Improvement) Response at Week 12</title>
        <description>The ACR20 response rate was based on 20% improvement relative to Baseline in the following measures:&#xD;
TJC based on 78 joints&#xD;
SJC based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by PGADA&#xD;
Disease activity as assessed by PhGADA&#xD;
Pain as assessed by PtAAP&#xD;
Physical function as assessed by HAQ-DI&#xD;
Acute phase response as assessed by hs CRP&#xD;
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.</description>
        <time_frame>Week 12</time_frame>
        <population>The FAS consisted of all randomized study participants who received at least 1 dose of IMP and had a valid measurement of the primary efficacy variable at Baseline.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (FAS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
        </group_list>
        <measure>
          <title>ACR20 (American College of Rheumatology 20% Improvement) Response at Week 12</title>
          <description>The ACR20 response rate was based on 20% improvement relative to Baseline in the following measures:&#xD;
TJC based on 78 joints&#xD;
SJC based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by PGADA&#xD;
Disease activity as assessed by PhGADA&#xD;
Pain as assessed by PtAAP&#xD;
Physical function as assessed by HAQ-DI&#xD;
Acute phase response as assessed by hs CRP&#xD;
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.</description>
          <population>The FAS consisted of all randomized study participants who received at least 1 dose of IMP and had a valid measurement of the primary efficacy variable at Baseline.</population>
          <units>percentage of subjects</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="41"/>
                <count group_id="O3" value="41"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="19.0"/>
                    <measurement group_id="O2" value="53.7"/>
                    <measurement group_id="O3" value="73.2"/>
                    <measurement group_id="O4" value="61.0"/>
                    <measurement group_id="O5" value="51.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.002</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>4.6</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>1.73</ci_lower_limit>
            <ci_upper_limit>12.39</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O3</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>&lt;0.001</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>11.0</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>3.91</ci_lower_limit>
            <ci_upper_limit>30.95</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O4</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>&lt;0.001</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>6.2</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>2.31</ci_lower_limit>
            <ci_upper_limit>16.84</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O5</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.004</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>4.2</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>1.59</ci_lower_limit>
            <ci_upper_limit>11.35</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>ACR70 (American College of Rheumatology 70% Improvement) Response at Week 12</title>
        <description>The ACR70 response rate was based on 70% improvement relative to Baseline in the following measures:&#xD;
TJC based on 78 joints&#xD;
SJC based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by PGADA&#xD;
Disease activity as assessed by PhGADA&#xD;
Pain as assessed by PtAAP&#xD;
Physical function as assessed by HAQ-DI&#xD;
Acute phase response as assessed by hs CRP&#xD;
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.</description>
        <time_frame>Week 12</time_frame>
        <population>The FAS consisted of all randomized study participants who received at least 1 dose of IMP and had a valid measurement of the primary efficacy variable at Baseline.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (FAS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
        </group_list>
        <measure>
          <title>ACR70 (American College of Rheumatology 70% Improvement) Response at Week 12</title>
          <description>The ACR70 response rate was based on 70% improvement relative to Baseline in the following measures:&#xD;
TJC based on 78 joints&#xD;
SJC based on 76 joints&#xD;
3 of the 5 remaining core set measures:&#xD;
Disease activity as assessed by PGADA&#xD;
Disease activity as assessed by PhGADA&#xD;
Pain as assessed by PtAAP&#xD;
Physical function as assessed by HAQ-DI&#xD;
Acute phase response as assessed by hs CRP&#xD;
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.</description>
          <population>The FAS consisted of all randomized study participants who received at least 1 dose of IMP and had a valid measurement of the primary efficacy variable at Baseline.</population>
          <units>percentage of subjects</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="41"/>
                <count group_id="O3" value="41"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.8"/>
                    <measurement group_id="O2" value="12.2"/>
                    <measurement group_id="O3" value="19.5"/>
                    <measurement group_id="O4" value="31.7"/>
                    <measurement group_id="O5" value="14.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.279</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>2.4</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.50</ci_lower_limit>
            <ci_upper_limit>11.31</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O3</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.065</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>4.1</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.92</ci_lower_limit>
            <ci_upper_limit>17.88</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O4</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.006</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>7.5</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>1.77</ci_lower_limit>
            <ci_upper_limit>31.28</ci_upper_limit>
          </analysis>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O5</group_id>
            </group_id_list>
            <groups_desc>For differences in relation to Placebo: Odds Ratio, confidence interval, and p-value were derived from a logistic regression model including fixed effects for treatment, geographic region and prior Tumor Necrosis Factor (TNF) inhibitor exposure.</groups_desc>
            <non_inferiority_type>Other</non_inferiority_type>
            <p_value>=0.172</p_value>
            <p_value_desc>No sequential testing procedure was used for the secondary efficacy variables. The p-values were displayed as nominal p-values.</p_value_desc>
            <method>Regression, Logistic</method>
            <param_type>Odds Ratio (OR)</param_type>
            <param_value>2.9</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.63</ci_lower_limit>
            <ci_upper_limit>13.39</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>PASI90 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1</title>
        <description>The PASI90 response assessments are based on at least 90% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).&#xD;
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.</description>
        <time_frame>Week 12</time_frame>
        <population>Subset of of study participants in the FAS with at least (≥) 3 percent (%) psoriasis (PSO) Body Surface Area (BSA) at Baseline (NRI).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (FAS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
        </group_list>
        <measure>
          <title>PASI90 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1</title>
          <description>The PASI90 response assessments are based on at least 90% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).&#xD;
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.</description>
          <population>Subset of of study participants in the FAS with at least (≥) 3 percent (%) psoriasis (PSO) Body Surface Area (BSA) at Baseline (NRI).</population>
          <units>percentage of subjects</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="20"/>
                <count group_id="O2" value="14"/>
                <count group_id="O3" value="16"/>
                <count group_id="O4" value="17"/>
                <count group_id="O5" value="11"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10.0"/>
                    <measurement group_id="O2" value="35.7"/>
                    <measurement group_id="O3" value="62.5"/>
                    <measurement group_id="O4" value="52.9"/>
                    <measurement group_id="O5" value="45.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>PASI75 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1</title>
        <description>The PASI75 response assessments are based on at least 75% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).&#xD;
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.</description>
        <time_frame>Week 12</time_frame>
        <population>Subset of of study participants in the FAS with at least (≥) 3 percent (%) psoriasis (PSO) Body Surface Area (BSA) at Baseline (NRI).</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (FAS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (FAS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the Full Analysis Set (FAS).</description>
          </group>
        </group_list>
        <measure>
          <title>PASI75 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1</title>
          <description>The PASI75 response assessments are based on at least 75% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).&#xD;
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.</description>
          <population>Subset of of study participants in the FAS with at least (≥) 3 percent (%) psoriasis (PSO) Body Surface Area (BSA) at Baseline (NRI).</population>
          <units>percentage of subjects</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="20"/>
                <count group_id="O2" value="14"/>
                <count group_id="O3" value="16"/>
                <count group_id="O4" value="17"/>
                <count group_id="O5" value="11"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10.0"/>
                    <measurement group_id="O2" value="57.1"/>
                    <measurement group_id="O3" value="68.8"/>
                    <measurement group_id="O4" value="70.6"/>
                    <measurement group_id="O5" value="72.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Percentage of Participants With at Least One Adverse Event (AE) During the Study</title>
        <description>An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.</description>
        <time_frame>From Screening Period until the Safety Follow-Up Visit (up to Week 72)</time_frame>
        <population>The Safety Set (SS) consisted of all randomized study participants who received at least 1 dose of IMP. The 160mg LD group and 160mg groups are combined into one column to see the effect of the 160mg dose overall.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS) - up to Wk 12</title>
            <description>This arm consisted of all participants who received Placebo at any time in the study (up to Week 12). Participants formed the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS) - up to Wk 12</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) at any time in the study (up to Week 12). Participants formed the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg &amp; 160 mg LD (SS) - up to Wk 68</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) and Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 320 mg (SS) - up to Wk 68</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Percentage of Participants With at Least One Adverse Event (AE) During the Study</title>
          <description>An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.</description>
          <population>The Safety Set (SS) consisted of all randomized study participants who received at least 1 dose of IMP. The 160mg LD group and 160mg groups are combined into one column to see the effect of the 160mg dose overall.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="126"/>
                <count group_id="O4" value="80"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="57.1"/>
                    <measurement group_id="O2" value="33.33"/>
                    <measurement group_id="O3" value="74.6"/>
                    <measurement group_id="O4" value="72.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Percentage of Participants With at Least One Serious Adverse Event (SAE) During the Study</title>
        <description>A Serious Adverse Event (SAE) is any untoward medical occurrence that at any dose:&#xD;
Results in death&#xD;
Is life-threatening&#xD;
Requires in patient hospitalization or prolongation of existing hospitalization&#xD;
Is a congenital anomaly or birth defect&#xD;
Is an infection that requires treatment parenteral antibiotics&#xD;
Other important medical events which based on medical or scientific judgement may jeopardize the patients, or may require medical or surgical intervention to prevent any of the above.</description>
        <time_frame>From Screening Period until the Safety Follow-Up Visit (up to Week 72)</time_frame>
        <population>The Safety Set (SS) consisted of all randomized study participants who received at least 1 dose of IMP. The 160mg LD group and 160mg groups are combined into one column to see the effect of the 160mg dose overall.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS) - up to Wk 12</title>
            <description>This arm consisted of all participants who received Placebo at any time in the study (up to Week 12). Participants formed the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS) - up to Wk 12</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) at any time in the study (up to Week 12). Participants formed the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg &amp; 160 mg LD (SS) - up to Wk 68</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) and Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 320 mg (SS) - up to Wk 68</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Percentage of Participants With at Least One Serious Adverse Event (SAE) During the Study</title>
          <description>A Serious Adverse Event (SAE) is any untoward medical occurrence that at any dose:&#xD;
Results in death&#xD;
Is life-threatening&#xD;
Requires in patient hospitalization or prolongation of existing hospitalization&#xD;
Is a congenital anomaly or birth defect&#xD;
Is an infection that requires treatment parenteral antibiotics&#xD;
Other important medical events which based on medical or scientific judgement may jeopardize the patients, or may require medical or surgical intervention to prevent any of the above.</description>
          <population>The Safety Set (SS) consisted of all randomized study participants who received at least 1 dose of IMP. The 160mg LD group and 160mg groups are combined into one column to see the effect of the 160mg dose overall.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="126"/>
                <count group_id="O4" value="80"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.4"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="6.3"/>
                    <measurement group_id="O4" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Percentage of Participants Who Withdrew Due to an Adverse Event (AE) During the Study</title>
        <description>An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.</description>
        <time_frame>From Screening Period until the Safety Follow-Up Visit (up to Week 72)</time_frame>
        <population>The Safety Set (SS) consisted of all randomized study participants who received at least 1 dose of IMP. The 160mg LD group and 160mg groups are combined into one column to see the effect of the 160mg dose overall.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS) - up to Wk 12</title>
            <description>This arm consisted of all participants who received Placebo at any time in the study (up to Week 12). Participants formed the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS) - up to Wk 12</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) at any time in the study (up to Week 12). Participants formed the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg &amp; 160 mg LD (SS) - up to Wk 68</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) and Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 320 mg (SS) - up to Wk 68</title>
            <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Percentage of Participants Who Withdrew Due to an Adverse Event (AE) During the Study</title>
          <description>An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.</description>
          <population>The Safety Set (SS) consisted of all randomized study participants who received at least 1 dose of IMP. The 160mg LD group and 160mg groups are combined into one column to see the effect of the 160mg dose overall.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="126"/>
                <count group_id="O4" value="80"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.8"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="4.8"/>
                    <measurement group_id="O4" value="2.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Vital Signs During the Study (Diastolic Blood Pressure, Systolic Blood Pressure)</title>
        <description>Diastolic and systolic blood pressure were measured in millimeters of mercury (mmHg).</description>
        <time_frame>Baseline, 30 min and 1 hour post dose, Week 1, Week 2, pre- and post dose for the following Weeks: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 and 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Vital Signs During the Study (Diastolic Blood Pressure, Systolic Blood Pressure)</title>
          <description>Diastolic and systolic blood pressure were measured in millimeters of mercury (mmHg).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>mmHg</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Diastolic Blood Pressure 30 min post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.3" spread="8.9"/>
                    <measurement group_id="O2" value="-1.2" spread="4.9"/>
                    <measurement group_id="O3" value="-1.2" spread="5.4"/>
                    <measurement group_id="O4" value="0.6" spread="6.1"/>
                    <measurement group_id="O5" value="-0.6" spread="5.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure 1 h post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="8.8"/>
                    <measurement group_id="O2" value="-2.0" spread="6.3"/>
                    <measurement group_id="O3" value="-0.7" spread="8.1"/>
                    <measurement group_id="O4" value="1.2" spread="6.7"/>
                    <measurement group_id="O5" value="-1.0" spread="5.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="9.6"/>
                    <measurement group_id="O2" value="-0.3" spread="6.5"/>
                    <measurement group_id="O3" value="0.6" spread="11.4"/>
                    <measurement group_id="O4" value="-0.9" spread="6.6"/>
                    <measurement group_id="O5" value="-0.4" spread="6.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="10.4"/>
                    <measurement group_id="O2" value="-0.7" spread="6.5"/>
                    <measurement group_id="O3" value="-1.0" spread="8.9"/>
                    <measurement group_id="O4" value="-2.7" spread="8.3"/>
                    <measurement group_id="O5" value="-0.1" spread="9.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 4 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="8.2"/>
                    <measurement group_id="O2" value="-1.7" spread="8.4"/>
                    <measurement group_id="O3" value="-1.4" spread="10.7"/>
                    <measurement group_id="O4" value="-0.8" spread="7.8"/>
                    <measurement group_id="O5" value="-1.3" spread="7.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 4 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="40"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="8.7"/>
                    <measurement group_id="O2" value="-1.0" spread="7.3"/>
                    <measurement group_id="O3" value="-1.2" spread="8.9"/>
                    <measurement group_id="O4" value="-0.9" spread="8.3"/>
                    <measurement group_id="O5" value="-1.6" spread="7.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 8 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.0" spread="8.2"/>
                    <measurement group_id="O2" value="-1.3" spread="8.7"/>
                    <measurement group_id="O3" value="0.3" spread="8.7"/>
                    <measurement group_id="O4" value="-0.5" spread="7.0"/>
                    <measurement group_id="O5" value="0.2" spread="6.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 8 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.9" spread="9.1"/>
                    <measurement group_id="O2" value="-1.1" spread="8.4"/>
                    <measurement group_id="O3" value="0.6" spread="8.7"/>
                    <measurement group_id="O4" value="-0.7" spread="7.3"/>
                    <measurement group_id="O5" value="-2.2" spread="7.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 12 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2" spread="9.1"/>
                    <measurement group_id="O2" value="-1.1" spread="10.4"/>
                    <measurement group_id="O3" value="0.2" spread="8.5"/>
                    <measurement group_id="O4" value="-1.5" spread="7.9"/>
                    <measurement group_id="O5" value="-0.6" spread="8.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 12 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.3" spread="9.6"/>
                    <measurement group_id="O2" value="-2.0" spread="10.0"/>
                    <measurement group_id="O3" value="0.3" spread="8.3"/>
                    <measurement group_id="O4" value="-1.8" spread="7.9"/>
                    <measurement group_id="O5" value="-2.6" spread="8.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 16 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.7" spread="9.6"/>
                    <measurement group_id="O2" value="-3.5" spread="8.9"/>
                    <measurement group_id="O3" value="-0.8" spread="8.6"/>
                    <measurement group_id="O4" value="-1.2" spread="8.7"/>
                    <measurement group_id="O5" value="-0.4" spread="7.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 16 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.0" spread="9.1"/>
                    <measurement group_id="O2" value="-1.9" spread="8.3"/>
                    <measurement group_id="O3" value="-1.7" spread="9.2"/>
                    <measurement group_id="O4" value="-1.1" spread="7.9"/>
                    <measurement group_id="O5" value="-2.4" spread="8.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 20 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.5" spread="10.3"/>
                    <measurement group_id="O2" value="-1.8" spread="9.0"/>
                    <measurement group_id="O3" value="-0.6" spread="8.3"/>
                    <measurement group_id="O4" value="-1.4" spread="8.3"/>
                    <measurement group_id="O5" value="-1.8" spread="7.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 20 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.1" spread="9.5"/>
                    <measurement group_id="O2" value="-3.1" spread="8.3"/>
                    <measurement group_id="O3" value="-0.4" spread="9.2"/>
                    <measurement group_id="O4" value="-3.0" spread="9.3"/>
                    <measurement group_id="O5" value="-2.6" spread="7.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 24 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.4" spread="7.6"/>
                    <measurement group_id="O2" value="-1.6" spread="7.2"/>
                    <measurement group_id="O3" value="-0.7" spread="9.3"/>
                    <measurement group_id="O4" value="1.0" spread="6.9"/>
                    <measurement group_id="O5" value="-1.0" spread="6.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 24 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="7.5"/>
                    <measurement group_id="O2" value="-1.7" spread="7.9"/>
                    <measurement group_id="O3" value="-0.3" spread="8.2"/>
                    <measurement group_id="O4" value="-0.3" spread="7.6"/>
                    <measurement group_id="O5" value="-1.4" spread="7.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 28 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" spread="7.9"/>
                    <measurement group_id="O2" value="-0.6" spread="9.7"/>
                    <measurement group_id="O3" value="0.9" spread="9.5"/>
                    <measurement group_id="O4" value="-0.6" spread="6.9"/>
                    <measurement group_id="O5" value="-0.5" spread="7.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 28 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.2" spread="8.7"/>
                    <measurement group_id="O2" value="-2.0" spread="9.4"/>
                    <measurement group_id="O3" value="1.2" spread="9.0"/>
                    <measurement group_id="O4" value="-0.2" spread="7.1"/>
                    <measurement group_id="O5" value="-1.8" spread="7.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 32 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.2" spread="8.5"/>
                    <measurement group_id="O2" value="-1.7" spread="8.6"/>
                    <measurement group_id="O3" value="1.6" spread="9.2"/>
                    <measurement group_id="O4" value="-0.3" spread="9.3"/>
                    <measurement group_id="O5" value="-1.2" spread="8.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 32 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="37"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="10.0"/>
                    <measurement group_id="O2" value="-3.0" spread="8.6"/>
                    <measurement group_id="O3" value="0.1" spread="9.6"/>
                    <measurement group_id="O4" value="-0.6" spread="8.5"/>
                    <measurement group_id="O5" value="-2.1" spread="8.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 36 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.0" spread="8.6"/>
                    <measurement group_id="O2" value="-0.6" spread="9.2"/>
                    <measurement group_id="O3" value="1.4" spread="8.9"/>
                    <measurement group_id="O4" value="-0.9" spread="7.2"/>
                    <measurement group_id="O5" value="0.8" spread="7.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 36 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="31"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.6" spread="7.7"/>
                    <measurement group_id="O2" value="-1.6" spread="9.2"/>
                    <measurement group_id="O3" value="1.3" spread="9.3"/>
                    <measurement group_id="O4" value="-1.7" spread="6.8"/>
                    <measurement group_id="O5" value="-0.1" spread="7.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 40 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.8" spread="7.6"/>
                    <measurement group_id="O2" value="-2.5" spread="9.7"/>
                    <measurement group_id="O3" value="1.0" spread="9.5"/>
                    <measurement group_id="O4" value="-1.0" spread="7.2"/>
                    <measurement group_id="O5" value="-1.9" spread="6.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 40 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="37"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.9" spread="7.7"/>
                    <measurement group_id="O2" value="-1.8" spread="9.1"/>
                    <measurement group_id="O3" value="0.2" spread="8.3"/>
                    <measurement group_id="O4" value="-0.8" spread="6.6"/>
                    <measurement group_id="O5" value="-0.1" spread="7.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 44 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" spread="9.3"/>
                    <measurement group_id="O2" value="-2.1" spread="7.7"/>
                    <measurement group_id="O3" value="1.3" spread="9.2"/>
                    <measurement group_id="O4" value="-0.4" spread="6.7"/>
                    <measurement group_id="O5" value="-2.4" spread="10.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 44 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3" spread="9.2"/>
                    <measurement group_id="O2" value="-1.3" spread="7.6"/>
                    <measurement group_id="O3" value="-0.7" spread="8.7"/>
                    <measurement group_id="O4" value="-1.4" spread="8.1"/>
                    <measurement group_id="O5" value="-1.5" spread="6.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Diastolic Blood Pressure Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.8" spread="9.2"/>
                    <measurement group_id="O2" value="0.4" spread="9.7"/>
                    <measurement group_id="O3" value="1.1" spread="9.1"/>
                    <measurement group_id="O4" value="0.6" spread="8.7"/>
                    <measurement group_id="O5" value="-0.8" spread="6.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure 30 min post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.8" spread="8.1"/>
                    <measurement group_id="O2" value="0.5" spread="9.7"/>
                    <measurement group_id="O3" value="-0.8" spread="8.2"/>
                    <measurement group_id="O4" value="1.5" spread="8.8"/>
                    <measurement group_id="O5" value="-2.5" spread="9.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure 1 hour post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="9.4"/>
                    <measurement group_id="O2" value="-2.0" spread="10.5"/>
                    <measurement group_id="O3" value="0.2" spread="8.7"/>
                    <measurement group_id="O4" value="1.0" spread="8.4"/>
                    <measurement group_id="O5" value="-1.8" spread="7.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="10.8"/>
                    <measurement group_id="O2" value="-1.3" spread="10.0"/>
                    <measurement group_id="O3" value="1.7" spread="12.9"/>
                    <measurement group_id="O4" value="-2.4" spread="8.3"/>
                    <measurement group_id="O5" value="-1.6" spread="11.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="12.9"/>
                    <measurement group_id="O2" value="-0.2" spread="9.8"/>
                    <measurement group_id="O3" value="-0.1" spread="13.2"/>
                    <measurement group_id="O4" value="-2.7" spread="8.2"/>
                    <measurement group_id="O5" value="-0.4" spread="11.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 4 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.6" spread="11.4"/>
                    <measurement group_id="O2" value="-1.5" spread="10.6"/>
                    <measurement group_id="O3" value="-1.0" spread="13.0"/>
                    <measurement group_id="O4" value="-2.3" spread="10.5"/>
                    <measurement group_id="O5" value="-2.7" spread="11.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 4 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="40"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.5" spread="12.1"/>
                    <measurement group_id="O2" value="-0.6" spread="10.4"/>
                    <measurement group_id="O3" value="-2.2" spread="11.8"/>
                    <measurement group_id="O4" value="-0.6" spread="9.1"/>
                    <measurement group_id="O5" value="-3.7" spread="11.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 8 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.1" spread="13.1"/>
                    <measurement group_id="O2" value="-0.8" spread="10.7"/>
                    <measurement group_id="O3" value="-1.1" spread="11.3"/>
                    <measurement group_id="O4" value="-3.6" spread="11.7"/>
                    <measurement group_id="O5" value="-1.3" spread="10.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 8 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.2" spread="12.6"/>
                    <measurement group_id="O2" value="-1.9" spread="11.6"/>
                    <measurement group_id="O3" value="-0.3" spread="11.1"/>
                    <measurement group_id="O4" value="-2.8" spread="10.2"/>
                    <measurement group_id="O5" value="-1.9" spread="12.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 12 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.3" spread="12.4"/>
                    <measurement group_id="O2" value="1.6" spread="13.7"/>
                    <measurement group_id="O3" value="-3.1" spread="11.7"/>
                    <measurement group_id="O4" value="-4.4" spread="10.8"/>
                    <measurement group_id="O5" value="-2.6" spread="9.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 12 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.9" spread="14.1"/>
                    <measurement group_id="O2" value="2.1" spread="11.1"/>
                    <measurement group_id="O3" value="-1.9" spread="12.0"/>
                    <measurement group_id="O4" value="-3.6" spread="10.1"/>
                    <measurement group_id="O5" value="-2.4" spread="10.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 16 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.6" spread="15.1"/>
                    <measurement group_id="O2" value="-2.3" spread="12.3"/>
                    <measurement group_id="O3" value="-4.3" spread="11.3"/>
                    <measurement group_id="O4" value="-4.3" spread="12.5"/>
                    <measurement group_id="O5" value="-2.3" spread="11.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 16 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.7" spread="17.1"/>
                    <measurement group_id="O2" value="-2.6" spread="11.7"/>
                    <measurement group_id="O3" value="-3.4" spread="12.7"/>
                    <measurement group_id="O4" value="-2.7" spread="11.0"/>
                    <measurement group_id="O5" value="-5.7" spread="8.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 20 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="13.1"/>
                    <measurement group_id="O2" value="-3.2" spread="12.5"/>
                    <measurement group_id="O3" value="-2.6" spread="11.9"/>
                    <measurement group_id="O4" value="-5.4" spread="9.7"/>
                    <measurement group_id="O5" value="-4.5" spread="10.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 20 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.9" spread="14.5"/>
                    <measurement group_id="O2" value="-3.2" spread="13.0"/>
                    <measurement group_id="O3" value="-3.7" spread="12.2"/>
                    <measurement group_id="O4" value="-7.9" spread="11.9"/>
                    <measurement group_id="O5" value="-4.4" spread="9.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 24 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.1" spread="10.5"/>
                    <measurement group_id="O2" value="-1.1" spread="9.5"/>
                    <measurement group_id="O3" value="-2.7" spread="12.3"/>
                    <measurement group_id="O4" value="-3.6" spread="10.1"/>
                    <measurement group_id="O5" value="-0.3" spread="10.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 24 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.6" spread="10.9"/>
                    <measurement group_id="O2" value="-2.8" spread="10.5"/>
                    <measurement group_id="O3" value="-2.2" spread="11.7"/>
                    <measurement group_id="O4" value="-3.0" spread="9.7"/>
                    <measurement group_id="O5" value="-1.1" spread="10.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 28 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="11.4"/>
                    <measurement group_id="O2" value="-2.5" spread="12.8"/>
                    <measurement group_id="O3" value="-2.5" spread="13.1"/>
                    <measurement group_id="O4" value="0.4" spread="11.6"/>
                    <measurement group_id="O5" value="-2.9" spread="11.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 28 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.1" spread="12.1"/>
                    <measurement group_id="O2" value="-2.9" spread="11.1"/>
                    <measurement group_id="O3" value="-2.6" spread="12.4"/>
                    <measurement group_id="O4" value="-0.7" spread="11.9"/>
                    <measurement group_id="O5" value="-4.6" spread="11.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 32 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.9" spread="13.1"/>
                    <measurement group_id="O2" value="-1.5" spread="13.3"/>
                    <measurement group_id="O3" value="-0.6" spread="12.4"/>
                    <measurement group_id="O4" value="0.6" spread="11.0"/>
                    <measurement group_id="O5" value="-3.7" spread="12.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 32 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="37"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="12.6"/>
                    <measurement group_id="O2" value="-2.2" spread="11.6"/>
                    <measurement group_id="O3" value="0.3" spread="12.5"/>
                    <measurement group_id="O4" value="-0.4" spread="11.1"/>
                    <measurement group_id="O5" value="-4.8" spread="10.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 36 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.1" spread="11.9"/>
                    <measurement group_id="O2" value="1.1" spread="13.9"/>
                    <measurement group_id="O3" value="-0.2" spread="13.6"/>
                    <measurement group_id="O4" value="-1.8" spread="11.2"/>
                    <measurement group_id="O5" value="-3.2" spread="11.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 36 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="31"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="11.1"/>
                    <measurement group_id="O2" value="1.3" spread="12.6"/>
                    <measurement group_id="O3" value="-0.5" spread="12.4"/>
                    <measurement group_id="O4" value="-3.8" spread="10.8"/>
                    <measurement group_id="O5" value="-3.8" spread="11.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 40 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.3" spread="12.1"/>
                    <measurement group_id="O2" value="-3.1" spread="11.4"/>
                    <measurement group_id="O3" value="-1.6" spread="12.9"/>
                    <measurement group_id="O4" value="-4.0" spread="9.5"/>
                    <measurement group_id="O5" value="-1.2" spread="11.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 40 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="37"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.3" spread="11.7"/>
                    <measurement group_id="O2" value="-0.4" spread="12.7"/>
                    <measurement group_id="O3" value="-1.2" spread="13.8"/>
                    <measurement group_id="O4" value="-3.2" spread="11.6"/>
                    <measurement group_id="O5" value="-2.2" spread="9.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 44 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.8" spread="12.3"/>
                    <measurement group_id="O2" value="-2.8" spread="9.9"/>
                    <measurement group_id="O3" value="0.0" spread="13.1"/>
                    <measurement group_id="O4" value="-5.1" spread="9.9"/>
                    <measurement group_id="O5" value="-3.9" spread="10.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 44 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.8" spread="14.5"/>
                    <measurement group_id="O2" value="-1.2" spread="9.5"/>
                    <measurement group_id="O3" value="-0.6" spread="10.4"/>
                    <measurement group_id="O4" value="-4.6" spread="10.3"/>
                    <measurement group_id="O5" value="-3.8" spread="10.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Systolic Blood Pressure Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.1" spread="14.0"/>
                    <measurement group_id="O2" value="-0.1" spread="12.5"/>
                    <measurement group_id="O3" value="-0.1" spread="12.6"/>
                    <measurement group_id="O4" value="-2.8" spread="11.5"/>
                    <measurement group_id="O5" value="-5.2" spread="9.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Vital Signs During the Study (Pulse Rate)</title>
        <description>Pulse rate was measured in beats per minute (beats/min).</description>
        <time_frame>Baseline, 30 min and 1 hour post dose, Week 1, Week 2, pre- and post dose for the following Weeks: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 and 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Vital Signs During the Study (Pulse Rate)</title>
          <description>Pulse rate was measured in beats per minute (beats/min).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>beats/min</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>30 min post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.4" spread="5.4"/>
                    <measurement group_id="O2" value="-0.8" spread="5.6"/>
                    <measurement group_id="O3" value="-1.5" spread="7.2"/>
                    <measurement group_id="O4" value="-2.3" spread="7.5"/>
                    <measurement group_id="O5" value="-1.1" spread="7.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>1 hour post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.3" spread="6.7"/>
                    <measurement group_id="O2" value="1.0" spread="11.3"/>
                    <measurement group_id="O3" value="-0.8" spread="7.6"/>
                    <measurement group_id="O4" value="-0.8" spread="8.1"/>
                    <measurement group_id="O5" value="-0.4" spread="7.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.9" spread="8.3"/>
                    <measurement group_id="O2" value="-1.5" spread="7.5"/>
                    <measurement group_id="O3" value="-0.7" spread="7.1"/>
                    <measurement group_id="O4" value="0.6" spread="8.9"/>
                    <measurement group_id="O5" value="-0.8" spread="9.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.2" spread="6.4"/>
                    <measurement group_id="O2" value="-1.7" spread="5.7"/>
                    <measurement group_id="O3" value="-0.7" spread="7.9"/>
                    <measurement group_id="O4" value="-1.0" spread="9.1"/>
                    <measurement group_id="O5" value="-0.4" spread="6.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="5.3"/>
                    <measurement group_id="O2" value="-2.1" spread="6.9"/>
                    <measurement group_id="O3" value="-1.9" spread="8.1"/>
                    <measurement group_id="O4" value="0.1" spread="9.8"/>
                    <measurement group_id="O5" value="-1.0" spread="6.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="40"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.4" spread="8.6"/>
                    <measurement group_id="O2" value="-2.6" spread="6.6"/>
                    <measurement group_id="O3" value="-2.7" spread="9.5"/>
                    <measurement group_id="O4" value="-0.5" spread="9.4"/>
                    <measurement group_id="O5" value="-1.1" spread="6.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.9" spread="6.5"/>
                    <measurement group_id="O2" value="-0.6" spread="8.0"/>
                    <measurement group_id="O3" value="-1.6" spread="8.6"/>
                    <measurement group_id="O4" value="0.8" spread="6.9"/>
                    <measurement group_id="O5" value="-1.3" spread="8.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="6.9"/>
                    <measurement group_id="O2" value="-1.3" spread="8.6"/>
                    <measurement group_id="O3" value="-1.9" spread="8.6"/>
                    <measurement group_id="O4" value="0.0" spread="8.5"/>
                    <measurement group_id="O5" value="-2.3" spread="8.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="10.2"/>
                    <measurement group_id="O2" value="-2.2" spread="8.5"/>
                    <measurement group_id="O3" value="-2.9" spread="10.5"/>
                    <measurement group_id="O4" value="-1.7" spread="9.5"/>
                    <measurement group_id="O5" value="-1.1" spread="8.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="8.8"/>
                    <measurement group_id="O2" value="-3.3" spread="8.8"/>
                    <measurement group_id="O3" value="-3.6" spread="9.4"/>
                    <measurement group_id="O4" value="-2.1" spread="9.7"/>
                    <measurement group_id="O5" value="-2.0" spread="7.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.2" spread="8.5"/>
                    <measurement group_id="O2" value="-2.1" spread="5.8"/>
                    <measurement group_id="O3" value="-2.9" spread="8.0"/>
                    <measurement group_id="O4" value="-1.9" spread="10.1"/>
                    <measurement group_id="O5" value="-1.3" spread="7.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="9.9"/>
                    <measurement group_id="O2" value="-3.5" spread="5.5"/>
                    <measurement group_id="O3" value="-3.7" spread="9.7"/>
                    <measurement group_id="O4" value="-2.1" spread="9.8"/>
                    <measurement group_id="O5" value="-2.2" spread="7.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="10.3"/>
                    <measurement group_id="O2" value="-2.4" spread="7.0"/>
                    <measurement group_id="O3" value="-1.7" spread="10.3"/>
                    <measurement group_id="O4" value="0.0" spread="9.0"/>
                    <measurement group_id="O5" value="-1.2" spread="9.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="6.8"/>
                    <measurement group_id="O2" value="-2.3" spread="7.8"/>
                    <measurement group_id="O3" value="-2.1" spread="9.7"/>
                    <measurement group_id="O4" value="-0.1" spread="8.5"/>
                    <measurement group_id="O5" value="-1.3" spread="8.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.5" spread="7.9"/>
                    <measurement group_id="O2" value="-2.0" spread="8.1"/>
                    <measurement group_id="O3" value="-2.8" spread="10.4"/>
                    <measurement group_id="O4" value="-0.7" spread="7.3"/>
                    <measurement group_id="O5" value="-1.2" spread="7.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.9" spread="7.8"/>
                    <measurement group_id="O2" value="-2.9" spread="8.5"/>
                    <measurement group_id="O3" value="-3.0" spread="9.6"/>
                    <measurement group_id="O4" value="-1.3" spread="6.9"/>
                    <measurement group_id="O5" value="-2.5" spread="7.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.9" spread="9.7"/>
                    <measurement group_id="O2" value="-2.1" spread="10.0"/>
                    <measurement group_id="O3" value="0.0" spread="9.3"/>
                    <measurement group_id="O4" value="-0.5" spread="11.2"/>
                    <measurement group_id="O5" value="0.2" spread="8.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.8" spread="7.5"/>
                    <measurement group_id="O2" value="-3.0" spread="9.4"/>
                    <measurement group_id="O3" value="-0.5" spread="8.5"/>
                    <measurement group_id="O4" value="-0.8" spread="10.0"/>
                    <measurement group_id="O5" value="0.0" spread="7.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.3" spread="10.0"/>
                    <measurement group_id="O2" value="-0.9" spread="7.9"/>
                    <measurement group_id="O3" value="-2.0" spread="9.2"/>
                    <measurement group_id="O4" value="-1.2" spread="10.6"/>
                    <measurement group_id="O5" value="-0.3" spread="7.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="37"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.3" spread="8.4"/>
                    <measurement group_id="O2" value="-0.8" spread="7.8"/>
                    <measurement group_id="O3" value="-3.0" spread="9.5"/>
                    <measurement group_id="O4" value="-1.9" spread="9.6"/>
                    <measurement group_id="O5" value="-2.0" spread="8.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.7" spread="8.5"/>
                    <measurement group_id="O2" value="0.2" spread="7.5"/>
                    <measurement group_id="O3" value="-2.6" spread="8.6"/>
                    <measurement group_id="O4" value="-2.6" spread="10.2"/>
                    <measurement group_id="O5" value="-0.5" spread="9.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="38"/>
                    <count group_id="O4" value="31"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.1" spread="7.6"/>
                    <measurement group_id="O2" value="-0.8" spread="8.2"/>
                    <measurement group_id="O3" value="-3.0" spread="9.8"/>
                    <measurement group_id="O4" value="-2.5" spread="8.2"/>
                    <measurement group_id="O5" value="-1.4" spread="9.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.7" spread="10.3"/>
                    <measurement group_id="O2" value="-0.5" spread="8.8"/>
                    <measurement group_id="O3" value="1.0" spread="10.1"/>
                    <measurement group_id="O4" value="-1.7" spread="7.6"/>
                    <measurement group_id="O5" value="2.0" spread="9.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="37"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.9" spread="8.3"/>
                    <measurement group_id="O2" value="-1.7" spread="8.3"/>
                    <measurement group_id="O3" value="0.0" spread="8.9"/>
                    <measurement group_id="O4" value="-2.0" spread="8.4"/>
                    <measurement group_id="O5" value="0.5" spread="9.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44 pre-dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.2" spread="8.9"/>
                    <measurement group_id="O2" value="-1.6" spread="6.9"/>
                    <measurement group_id="O3" value="-0.4" spread="10.1"/>
                    <measurement group_id="O4" value="-1.4" spread="8.2"/>
                    <measurement group_id="O5" value="0.7" spread="9.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44 post dose</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.9" spread="6.9"/>
                    <measurement group_id="O2" value="-1.7" spread="8.0"/>
                    <measurement group_id="O3" value="-0.5" spread="11.0"/>
                    <measurement group_id="O4" value="-2.8" spread="7.7"/>
                    <measurement group_id="O5" value="-0.2" spread="10.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.0" spread="8.9"/>
                    <measurement group_id="O2" value="-3.7" spread="7.8"/>
                    <measurement group_id="O3" value="-2.5" spread="10.4"/>
                    <measurement group_id="O4" value="-4.2" spread="9.5"/>
                    <measurement group_id="O5" value="-3.1" spread="9.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Body Weight During the Study</title>
        <description>Body weight was measured in kilograms.</description>
        <time_frame>Baseline, Week 12, Week 24, Week 36 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.&#xD;
Overall number of participants analyzed include only those for whom body weight was measured and analyzed during the study.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Body Weight During the Study</title>
          <description>Body weight was measured in kilograms.</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.&#xD;
Overall number of participants analyzed include only those for whom body weight was measured and analyzed during the study.</population>
          <units>kilograms</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="41"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="38"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.14" spread="3.38"/>
                    <measurement group_id="O2" value="-0.87" spread="3.12"/>
                    <measurement group_id="O3" value="0.21" spread="1.78"/>
                    <measurement group_id="O4" value="-0.38" spread="1.80"/>
                    <measurement group_id="O5" value="-0.04" spread="2.39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.33" spread="4.10"/>
                    <measurement group_id="O2" value="-0.03" spread="3.48"/>
                    <measurement group_id="O3" value="-0.07" spread="2.63"/>
                    <measurement group_id="O4" value="-0.13" spread="2.37"/>
                    <measurement group_id="O5" value="-0.39" spread="3.73"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.32" spread="5.15"/>
                    <measurement group_id="O2" value="-0.14" spread="2.90"/>
                    <measurement group_id="O3" value="0.27" spread="3.42"/>
                    <measurement group_id="O4" value="0.15" spread="2.36"/>
                    <measurement group_id="O5" value="-0.04" spread="4.19"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.21" spread="4.42"/>
                    <measurement group_id="O2" value="0.45" spread="3.41"/>
                    <measurement group_id="O3" value="0.80" spread="3.84"/>
                    <measurement group_id="O4" value="-0.14" spread="3.32"/>
                    <measurement group_id="O5" value="0.11" spread="4.24"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Electrocardiogram (ECG) Intervals During the Study (QTcB, QTcF, PR, QRS, QT, RR)</title>
        <description>Electrocardiogram (ECG) intervals (QTcB= QT interval corrected for heart rate (Bazett's formula); QTcF= QT interval corrected for heart rate (Fridericia's formula)) were measured in milliseconds.</description>
        <time_frame>Baseline, Week 12 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.&#xD;
Overall number of participants analyzed include only those for whom electrocardiogram data was measured and analyzed during the study.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Electrocardiogram (ECG) Intervals During the Study (QTcB, QTcF, PR, QRS, QT, RR)</title>
          <description>Electrocardiogram (ECG) intervals (QTcB= QT interval corrected for heart rate (Bazett's formula); QTcF= QT interval corrected for heart rate (Fridericia's formula)) were measured in milliseconds.</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.&#xD;
Overall number of participants analyzed include only those for whom electrocardiogram data was measured and analyzed during the study.</population>
          <units>msec</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="40"/>
                <count group_id="O2" value="38"/>
                <count group_id="O3" value="42"/>
                <count group_id="O4" value="36"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>QTcB Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.4" spread="32.7"/>
                    <measurement group_id="O2" value="-2.8" spread="29.9"/>
                    <measurement group_id="O3" value="-5.6" spread="41.8"/>
                    <measurement group_id="O4" value="1.5" spread="18.2"/>
                    <measurement group_id="O5" value="-1.9" spread="31.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcB Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="35"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="31"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.5" spread="34.8"/>
                    <measurement group_id="O2" value="-5.8" spread="36.5"/>
                    <measurement group_id="O3" value="-5.9" spread="22.2"/>
                    <measurement group_id="O4" value="-4.7" spread="21.0"/>
                    <measurement group_id="O5" value="-5.7" spread="27.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="32"/>
                    <count group_id="O3" value="35"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.5" spread="27.5"/>
                    <measurement group_id="O2" value="-2.5" spread="22.4"/>
                    <measurement group_id="O3" value="-2.2" spread="14.2"/>
                    <measurement group_id="O4" value="-0.5" spread="17.0"/>
                    <measurement group_id="O5" value="-3.0" spread="18.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="35"/>
                    <count group_id="O2" value="32"/>
                    <count group_id="O3" value="34"/>
                    <count group_id="O4" value="29"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.1" spread="30.7"/>
                    <measurement group_id="O2" value="-6.1" spread="31.4"/>
                    <measurement group_id="O3" value="-0.2" spread="15.6"/>
                    <measurement group_id="O4" value="-2.2" spread="20.0"/>
                    <measurement group_id="O5" value="4.6" spread="44.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.7" spread="23.3"/>
                    <measurement group_id="O2" value="-1.0" spread="23.7"/>
                    <measurement group_id="O3" value="-19.6" spread="102.1"/>
                    <measurement group_id="O4" value="3.2" spread="18.2"/>
                    <measurement group_id="O5" value="-9.5" spread="32.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.6" spread="33.7"/>
                    <measurement group_id="O2" value="17.5" spread="128.8"/>
                    <measurement group_id="O3" value="4.0" spread="163.0"/>
                    <measurement group_id="O4" value="0.8" spread="18.9"/>
                    <measurement group_id="O5" value="-2.8" spread="26.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.6" spread="22.3"/>
                    <measurement group_id="O2" value="-2.9" spread="10.8"/>
                    <measurement group_id="O3" value="-1.8" spread="7.6"/>
                    <measurement group_id="O4" value="-0.2" spread="5.4"/>
                    <measurement group_id="O5" value="6.1" spread="42.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QRS Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.6" spread="21.4"/>
                    <measurement group_id="O2" value="-1.5" spread="16.1"/>
                    <measurement group_id="O3" value="-4.0" spread="13.0"/>
                    <measurement group_id="O4" value="0.6" spread="16.2"/>
                    <measurement group_id="O5" value="0.1" spread="18.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.0" spread="46.6"/>
                    <measurement group_id="O2" value="1.7" spread="34.0"/>
                    <measurement group_id="O3" value="9.5" spread="21.4"/>
                    <measurement group_id="O4" value="3.8" spread="25.6"/>
                    <measurement group_id="O5" value="11.5" spread="80.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QT Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.7" spread="33.4"/>
                    <measurement group_id="O2" value="3.1" spread="29.9"/>
                    <measurement group_id="O3" value="3.9" spread="22.8"/>
                    <measurement group_id="O4" value="5.4" spread="26.7"/>
                    <measurement group_id="O5" value="0.7" spread="31.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>RR Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.3" spread="99.3"/>
                    <measurement group_id="O2" value="-22.5" spread="212.6"/>
                    <measurement group_id="O3" value="75.8" spread="179.3"/>
                    <measurement group_id="O4" value="11.0" spread="125.1"/>
                    <measurement group_id="O5" value="-17.0" spread="182.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>RR Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="31"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.6" spread="116.1"/>
                    <measurement group_id="O2" value="11.9" spread="187.1"/>
                    <measurement group_id="O3" value="65.2" spread="139.0"/>
                    <measurement group_id="O4" value="44.3" spread="124.0"/>
                    <measurement group_id="O5" value="25.1" spread="148.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Basophils, Eosinophils, Leukocytes, Lymphocytes, Monocytes, Neutrophils)</title>
        <description>Basophils, eosinophils, leukocytes, lymphocytes, monocytes, neutrophils were measured in number of white blood cells per liter (10^9/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Basophils, Eosinophils, Leukocytes, Lymphocytes, Monocytes, Neutrophils)</title>
          <description>Basophils, eosinophils, leukocytes, lymphocytes, monocytes, neutrophils were measured in number of white blood cells per liter (10^9/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>10^9 white blood cells per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Basophils Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0387"/>
                    <measurement group_id="O2" value="0.000" spread="0.0329"/>
                    <measurement group_id="O3" value="-0.002" spread="0.0408"/>
                    <measurement group_id="O4" value="0.007" spread="0.0264"/>
                    <measurement group_id="O5" value="0.008" spread="0.0350"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0269"/>
                    <measurement group_id="O2" value="0.003" spread="0.0283"/>
                    <measurement group_id="O3" value="0.000" spread="0.0488"/>
                    <measurement group_id="O4" value="0.000" spread="0.0316"/>
                    <measurement group_id="O5" value="0.005" spread="0.0384"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0474"/>
                    <measurement group_id="O2" value="0.005" spread="0.0324"/>
                    <measurement group_id="O3" value="-0.007" spread="0.0463"/>
                    <measurement group_id="O4" value="0.005" spread="0.0312"/>
                    <measurement group_id="O5" value="0.005" spread="0.0312"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.002" spread="0.0353"/>
                    <measurement group_id="O2" value="0.000" spread="0.0229"/>
                    <measurement group_id="O3" value="-0.005" spread="0.0384"/>
                    <measurement group_id="O4" value="0.003" spread="0.0367"/>
                    <measurement group_id="O5" value="0.002" spread="0.0418"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0353"/>
                    <measurement group_id="O2" value="0.003" spread="0.0280"/>
                    <measurement group_id="O3" value="-0.002" spread="0.0462"/>
                    <measurement group_id="O4" value="0.000" spread="0.0329"/>
                    <measurement group_id="O5" value="0.010" spread="0.0374"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.010" spread="0.0431"/>
                    <measurement group_id="O2" value="0.005" spread="0.0324"/>
                    <measurement group_id="O3" value="-0.007" spread="0.0463"/>
                    <measurement group_id="O4" value="0.000" spread="0.0329"/>
                    <measurement group_id="O5" value="0.008" spread="0.0417"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.003" spread="0.0362"/>
                    <measurement group_id="O2" value="0.003" spread="0.0362"/>
                    <measurement group_id="O3" value="0.000" spread="0.0500"/>
                    <measurement group_id="O4" value="0.005" spread="0.0329"/>
                    <measurement group_id="O5" value="0.000" spread="0.0397"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0397"/>
                    <measurement group_id="O2" value="0.005" spread="0.0324"/>
                    <measurement group_id="O3" value="-0.003" spread="0.0530"/>
                    <measurement group_id="O4" value="0.008" spread="0.0368"/>
                    <measurement group_id="O5" value="0.005" spread="0.0389"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.005" spread="0.0394"/>
                    <measurement group_id="O2" value="0.000" spread="0.0329"/>
                    <measurement group_id="O3" value="0.008" spread="0.0526"/>
                    <measurement group_id="O4" value="0.011" spread="0.0323"/>
                    <measurement group_id="O5" value="0.005" spread="0.0450"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0324"/>
                    <measurement group_id="O2" value="0.005" spread="0.0320"/>
                    <measurement group_id="O3" value="-0.010" spread="0.0441"/>
                    <measurement group_id="O4" value="0.009" spread="0.0379"/>
                    <measurement group_id="O5" value="0.010" spread="0.0384"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0408"/>
                    <measurement group_id="O2" value="0.003" spread="0.0283"/>
                    <measurement group_id="O3" value="-0.002" spread="0.0474"/>
                    <measurement group_id="O4" value="0.012" spread="0.0415"/>
                    <measurement group_id="O5" value="0.013" spread="0.0409"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.003" spread="0.0506"/>
                    <measurement group_id="O2" value="0.005" spread="0.0399"/>
                    <measurement group_id="O3" value="-0.010" spread="0.0379"/>
                    <measurement group_id="O4" value="0.006" spread="0.0343"/>
                    <measurement group_id="O5" value="0.000" spread="0.0403"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.006" spread="0.0410"/>
                    <measurement group_id="O2" value="0.003" spread="0.0372"/>
                    <measurement group_id="O3" value="0.000" spread="0.0387"/>
                    <measurement group_id="O4" value="0.006" spread="0.0422"/>
                    <measurement group_id="O5" value="0.000" spread="0.0338"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Basophils Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.005" spread="0.0462"/>
                    <measurement group_id="O2" value="0.003" spread="0.291"/>
                    <measurement group_id="O3" value="-0.010" spread="0.0441"/>
                    <measurement group_id="O4" value="0.006" spread="0.0354"/>
                    <measurement group_id="O5" value="0.000" spread="0.0324"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.010" spread="0.0860"/>
                    <measurement group_id="O2" value="0.016" spread="0.0718"/>
                    <measurement group_id="O3" value="-0.002" spread="0.0801"/>
                    <measurement group_id="O4" value="-0.005" spread="0.0999"/>
                    <measurement group_id="O5" value="0.017" spread="0.0636"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.005" spread="0.0731"/>
                    <measurement group_id="O2" value="0.013" spread="0.0777"/>
                    <measurement group_id="O3" value="0.002" spread="0.0913"/>
                    <measurement group_id="O4" value="0.002" spread="0.0880"/>
                    <measurement group_id="O5" value="0.029" spread="0.0929"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0987"/>
                    <measurement group_id="O2" value="0.016" spread="0.0594"/>
                    <measurement group_id="O3" value="0.002" spread="0.0780"/>
                    <measurement group_id="O4" value="0.005" spread="0.0999"/>
                    <measurement group_id="O5" value="0.027" spread="0.0895"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.024" spread="0.0969"/>
                    <measurement group_id="O2" value="-0.003" spread="0.0707"/>
                    <measurement group_id="O3" value="0.000" spread="0.1000"/>
                    <measurement group_id="O4" value="0.008" spread="0.0941"/>
                    <measurement group_id="O5" value="0.005" spread="0.0669"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.020" spread="0.0954"/>
                    <measurement group_id="O2" value="0.010" spread="0.0882"/>
                    <measurement group_id="O3" value="0.002" spread="0.0831"/>
                    <measurement group_id="O4" value="-0.026" spread="0.1155"/>
                    <measurement group_id="O5" value="0.017" spread="0.0704"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.045" spread="0.1253"/>
                    <measurement group_id="O2" value="0.021" spread="0.0935"/>
                    <measurement group_id="O3" value="0.010" spread="0.0759"/>
                    <measurement group_id="O4" value="-0.005" spread="0.1559"/>
                    <measurement group_id="O5" value="0.033" spread="0.0829"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.036" spread="0.1038"/>
                    <measurement group_id="O2" value="0.026" spread="0.1186"/>
                    <measurement group_id="O3" value="0.024" spread="0.1157"/>
                    <measurement group_id="O4" value="-0.014" spread="0.1228"/>
                    <measurement group_id="O5" value="0.038" spread="0.0935"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.031" spread="0.1301"/>
                    <measurement group_id="O2" value="0.013" spread="0.0844"/>
                    <measurement group_id="O3" value="0.058" spread="0.2111"/>
                    <measurement group_id="O4" value="-0.019" spread="0.1238"/>
                    <measurement group_id="O5" value="0.037" spread="0.1192"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.036" spread="0.0986"/>
                    <measurement group_id="O2" value="0.018" spread="0.0926"/>
                    <measurement group_id="O3" value="0.053" spread="0.1826"/>
                    <measurement group_id="O4" value="-0.000" spread="0.1213"/>
                    <measurement group_id="O5" value="0.025" spread="0.0870"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.049" spread="0.1502"/>
                    <measurement group_id="O2" value="0.033" spread="0.0838"/>
                    <measurement group_id="O3" value="0.020" spread="0.1418"/>
                    <measurement group_id="O4" value="0.024" spread="0.1577"/>
                    <measurement group_id="O5" value="0.041" spread="0.1141"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.054" spread="0.1726"/>
                    <measurement group_id="O2" value="0.018" spread="0.0955"/>
                    <measurement group_id="O3" value="0.022" spread="0.0909"/>
                    <measurement group_id="O4" value="0.027" spread="0.1526"/>
                    <measurement group_id="O5" value="0.015" spread="0.0961"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.050" spread="0.1444"/>
                    <measurement group_id="O2" value="0.018" spread="0.0865"/>
                    <measurement group_id="O3" value="0.018" spread="0.0958"/>
                    <measurement group_id="O4" value="0.015" spread="0.1971"/>
                    <measurement group_id="O5" value="0.039" spread="0.1128"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.072" spread="0.1523"/>
                    <measurement group_id="O2" value="0.019" spread="0.0908"/>
                    <measurement group_id="O3" value="0.024" spread="0.0994"/>
                    <measurement group_id="O4" value="-0.009" spread="0.1798"/>
                    <measurement group_id="O5" value="0.006" spread="0.0893"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophils Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.045" spread="0.1811"/>
                    <measurement group_id="O2" value="0.006" spread="0.0754"/>
                    <measurement group_id="O3" value="0.023" spread="0.0891"/>
                    <measurement group_id="O4" value="0.009" spread="0.2833"/>
                    <measurement group_id="O5" value="-0.005" spread="0.0857"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.271" spread="1.1885"/>
                    <measurement group_id="O2" value="-0.597" spread="1.1490"/>
                    <measurement group_id="O3" value="-0.656" spread="1.2593"/>
                    <measurement group_id="O4" value="-1.029" spread="1.6496"/>
                    <measurement group_id="O5" value="-0.285" spread="1.6896"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.157" spread="1.3195"/>
                    <measurement group_id="O2" value="-0.131" spread="2.1769"/>
                    <measurement group_id="O3" value="-0.309" spread="1.3735"/>
                    <measurement group_id="O4" value="-0.954" spread="2.0441"/>
                    <measurement group_id="O5" value="-0.322" spread="1.5501"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.049" spread="1.1938"/>
                    <measurement group_id="O2" value="-0.411" spread="1.1988"/>
                    <measurement group_id="O3" value="-0.336" spread="1.5088"/>
                    <measurement group_id="O4" value="-1.017" spread="1.9397"/>
                    <measurement group_id="O5" value="-0.656" spread="1.4264"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.429" spread="1.7036"/>
                    <measurement group_id="O2" value="-0.333" spread="1.4014"/>
                    <measurement group_id="O3" value="-0.185" spread="1.2889"/>
                    <measurement group_id="O4" value="-1.071" spread="1.9639"/>
                    <measurement group_id="O5" value="-0.629" spread="1.5489"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.190" spread="1.6223"/>
                    <measurement group_id="O2" value="-0.438" spread="1.3854"/>
                    <measurement group_id="O3" value="-0.495" spread="1.6904"/>
                    <measurement group_id="O4" value="-0.997" spread="2.1806"/>
                    <measurement group_id="O5" value="-0.634" spread="1.6084"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.400" spread="1.5616"/>
                    <measurement group_id="O2" value="-0.839" spread="1.8179"/>
                    <measurement group_id="O3" value="-0.590" spread="1.4668"/>
                    <measurement group_id="O4" value="-1.318" spread="2.3324"/>
                    <measurement group_id="O5" value="-0.293" spread="1.8427"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.936" spread="1.2756"/>
                    <measurement group_id="O2" value="-1.100" spread="1.5599"/>
                    <measurement group_id="O3" value="-0.432" spread="1.3032"/>
                    <measurement group_id="O4" value="-0.932" spread="2.2832"/>
                    <measurement group_id="O5" value="-0.455" spread="1.7116"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.251" spread="1.3888"/>
                    <measurement group_id="O2" value="-0.884" spread="1.7768"/>
                    <measurement group_id="O3" value="-0.495" spread="1.4216"/>
                    <measurement group_id="O4" value="-1.119" spread="2.2807"/>
                    <measurement group_id="O5" value="-0.765" spread="1.8691"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.700" spread="1.8180"/>
                    <measurement group_id="O2" value="-0.316" spread="2.3086"/>
                    <measurement group_id="O3" value="-0.100" spread="1.4942"/>
                    <measurement group_id="O4" value="-0.894" spread="1.7119"/>
                    <measurement group_id="O5" value="-0.342" spread="1.5683"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.762" spread="1.4273"/>
                    <measurement group_id="O2" value="-0.862" spread="2.0091"/>
                    <measurement group_id="O3" value="-0.330" spread="1.5750"/>
                    <measurement group_id="O4" value="-0.918" spread="2.6184"/>
                    <measurement group_id="O5" value="-0.505" spread="1.4800"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.541" spread="1.5971"/>
                    <measurement group_id="O2" value="-0.974" spread="1.7389"/>
                    <measurement group_id="O3" value="-0.366" spread="1.4549"/>
                    <measurement group_id="O4" value="-1.082" spread="2.3389"/>
                    <measurement group_id="O5" value="-0.126" spread="2.2565"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.783" spread="1.7693"/>
                    <measurement group_id="O2" value="-0.826" spread="1.5942"/>
                    <measurement group_id="O3" value="-0.437" spread="1.7878"/>
                    <measurement group_id="O4" value="-1.226" spread="2.3856"/>
                    <measurement group_id="O5" value="-0.266" spread="1.7976"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.065" spread="1.6070"/>
                    <measurement group_id="O2" value="-0.978" spread="1.8151"/>
                    <measurement group_id="O3" value="-0.537" spread="1.5641"/>
                    <measurement group_id="O4" value="-1.032" spread="2.1585"/>
                    <measurement group_id="O5" value="-0.825" spread="1.8917"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.739" spread="1.7774"/>
                    <measurement group_id="O2" value="-0.869" spread="1.7109"/>
                    <measurement group_id="O3" value="-0.473" spread="1.7104"/>
                    <measurement group_id="O4" value="-1.225" spread="2.5952"/>
                    <measurement group_id="O5" value="-0.777" spread="1.8593"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.083" spread="0.5074"/>
                    <measurement group_id="O2" value="-0.024" spread="0.4142"/>
                    <measurement group_id="O3" value="0.044" spread="0.5039"/>
                    <measurement group_id="O4" value="-0.017" spread="0.4189"/>
                    <measurement group_id="O5" value="0.020" spread="0.3006"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.105" spread="0.3246"/>
                    <measurement group_id="O2" value="0.026" spread="0.4137"/>
                    <measurement group_id="O3" value="0.021" spread="0.6006"/>
                    <measurement group_id="O4" value="0.007" spread="0.3643"/>
                    <measurement group_id="O5" value="0.161" spread="0.4277"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.037" spread="0.4386"/>
                    <measurement group_id="O2" value="0.024" spread="0.3259"/>
                    <measurement group_id="O3" value="0.010" spread="0.6003"/>
                    <measurement group_id="O4" value="-0.032" spread="0.3996"/>
                    <measurement group_id="O5" value="0.095" spread="0.3263"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.120" spread="0.3776"/>
                    <measurement group_id="O2" value="0.054" spread="0.3783"/>
                    <measurement group_id="O3" value="0.063" spread="0.5928"/>
                    <measurement group_id="O4" value="0.053" spread="0.4980"/>
                    <measurement group_id="O5" value="0.129" spread="0.3939"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.041" spread="0.3647"/>
                    <measurement group_id="O2" value="0.051" spread="0.4167"/>
                    <measurement group_id="O3" value="0.000" spread="0.5640"/>
                    <measurement group_id="O4" value="-0.047" spread="0.3703"/>
                    <measurement group_id="O5" value="0.061" spread="0.3301"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.052" spread="0.5567"/>
                    <measurement group_id="O2" value="0.071" spread="0.3571"/>
                    <measurement group_id="O3" value="0.026" spread="0.5539"/>
                    <measurement group_id="O4" value="-0.029" spread="0.4991"/>
                    <measurement group_id="O5" value="0.135" spread="0.4197"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.003" spread="0.4934"/>
                    <measurement group_id="O2" value="0.008" spread="0.3970"/>
                    <measurement group_id="O3" value="0.149" spread="0.4675"/>
                    <measurement group_id="O4" value="-0.035" spread="0.4566"/>
                    <measurement group_id="O5" value="0.126" spread="0.4216"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.041" spread="0.3905"/>
                    <measurement group_id="O2" value="0.050" spread="0.3630"/>
                    <measurement group_id="O3" value="0.048" spread="0.4455"/>
                    <measurement group_id="O4" value="-0.036" spread="0.3788"/>
                    <measurement group_id="O5" value="0.053" spread="0.3974"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.036" spread="0.5869"/>
                    <measurement group_id="O2" value="0.105" spread="0.3594"/>
                    <measurement group_id="O3" value="0.210" spread="0.5999"/>
                    <measurement group_id="O4" value="0.103" spread="0.5544"/>
                    <measurement group_id="O5" value="0.172" spread="0.3776"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.000" spread="0.5109"/>
                    <measurement group_id="O2" value="0.103" spread="0.4233"/>
                    <measurement group_id="O3" value="0.083" spread="0.6524"/>
                    <measurement group_id="O4" value="0.112" spread="0.5056"/>
                    <measurement group_id="O5" value="0.146" spread="0.3966"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.078" spread="0.4894"/>
                    <measurement group_id="O2" value="0.039" spread="0.4227"/>
                    <measurement group_id="O3" value="0.134" spread="0.5673"/>
                    <measurement group_id="O4" value="0.103" spread="0.5491"/>
                    <measurement group_id="O5" value="0.118" spread="0.3810"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.139" spread="0.4871"/>
                    <measurement group_id="O2" value="0.168" spread="0.4281"/>
                    <measurement group_id="O3" value="0.120" spread="0.6018"/>
                    <measurement group_id="O4" value="0.038" spread="0.4335"/>
                    <measurement group_id="O5" value="0.176" spread="0.3709"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.008" spread="0.5390"/>
                    <measurement group_id="O2" value="0.105" spread="0.4136"/>
                    <measurement group_id="O3" value="0.124" spread="0.5366"/>
                    <measurement group_id="O4" value="0.115" spread="0.4881"/>
                    <measurement group_id="O5" value="0.153" spread="0.4462"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocytes Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.066" spread="0.5313"/>
                    <measurement group_id="O2" value="0.103" spread="0.3645"/>
                    <measurement group_id="O3" value="0.078" spread="0.5041"/>
                    <measurement group_id="O4" value="0.019" spread="0.3763"/>
                    <measurement group_id="O5" value="0.072" spread="0.3755"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.007" spread="0.2184"/>
                    <measurement group_id="O2" value="-0.008" spread="0.1477"/>
                    <measurement group_id="O3" value="-0.012" spread="0.1679"/>
                    <measurement group_id="O4" value="-0.088" spread="0.2315"/>
                    <measurement group_id="O5" value="-0.027" spread="0.1724"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.076" spread="0.1358"/>
                    <measurement group_id="O2" value="-0.011" spread="0.1673"/>
                    <measurement group_id="O3" value="0.014" spread="0.1897"/>
                    <measurement group_id="O4" value="-0.095" spread="0.2701"/>
                    <measurement group_id="O5" value="-0.010" spread="0.1882"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.032" spread="0.1588"/>
                    <measurement group_id="O2" value="-0.021" spread="0.1473"/>
                    <measurement group_id="O3" value="-0.040" spread="0.1862"/>
                    <measurement group_id="O4" value="-0.066" spread="0.2404"/>
                    <measurement group_id="O5" value="-0.085" spread="0.1459"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.059" spread="0.1910"/>
                    <measurement group_id="O2" value="-0.041" spread="0.1743"/>
                    <measurement group_id="O3" value="0.005" spread="0.1580"/>
                    <measurement group_id="O4" value="-0.103" spread="0.2520"/>
                    <measurement group_id="O5" value="-0.071" spread="0.1834"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.020" spread="0.1913"/>
                    <measurement group_id="O2" value="-0.031" spread="0.1608"/>
                    <measurement group_id="O3" value="-0.033" spread="0.1686"/>
                    <measurement group_id="O4" value="-0.105" spread="0.2630"/>
                    <measurement group_id="O5" value="-0.059" spread="0.1414"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="0.1629"/>
                    <measurement group_id="O2" value="-0.050" spread="0.1673"/>
                    <measurement group_id="O3" value="-0.024" spread="0.1265"/>
                    <measurement group_id="O4" value="-0.079" spread="0.2384"/>
                    <measurement group_id="O5" value="-0.043" spread="0.1752"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.008" spread="0.1783"/>
                    <measurement group_id="O2" value="-0.041" spread="0.1534"/>
                    <measurement group_id="O3" value="-0.015" spread="0.1509"/>
                    <measurement group_id="O4" value="-0.081" spread="0.2448"/>
                    <measurement group_id="O5" value="-0.003" spread="0.1899"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.026" spread="0.1292"/>
                    <measurement group_id="O2" value="-0.034" spread="0.1361"/>
                    <measurement group_id="O3" value="0.003" spread="0.1476"/>
                    <measurement group_id="O4" value="-0.056" spread="0.2602"/>
                    <measurement group_id="O5" value="-0.027" spread="0.1921"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.026" spread="0.2087"/>
                    <measurement group_id="O2" value="0.042" spread="0.1981"/>
                    <measurement group_id="O3" value="0.055" spread="0.1724"/>
                    <measurement group_id="O4" value="-0.029" spread="0.2729"/>
                    <measurement group_id="O5" value="-0.012" spread="0.1911"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.064" spread="0.2356"/>
                    <measurement group_id="O2" value="-0.005" spread="0.1731"/>
                    <measurement group_id="O3" value="-0.003" spread="0.1271"/>
                    <measurement group_id="O4" value="-0.035" spread="0.2684"/>
                    <measurement group_id="O5" value="0.010" spread="0.1744"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.054" spread="0.1626"/>
                    <measurement group_id="O2" value="-0.024" spread="0.1792"/>
                    <measurement group_id="O3" value="0.032" spread="0.1404"/>
                    <measurement group_id="O4" value="-0.036" spread="0.2644"/>
                    <measurement group_id="O5" value="0.049" spread="0.2327"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.053" spread="0.1647"/>
                    <measurement group_id="O2" value="0.008" spread="0.1323"/>
                    <measurement group_id="O3" value="0.020" spread="0.1636"/>
                    <measurement group_id="O4" value="-0.059" spread="0.2830"/>
                    <measurement group_id="O5" value="-0.018" spread="0.1504"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.019" spread="0.1939"/>
                    <measurement group_id="O2" value="-0.008" spread="0.1588"/>
                    <measurement group_id="O3" value="0.044" spread="0.1644"/>
                    <measurement group_id="O4" value="-0.032" spread="0.2446"/>
                    <measurement group_id="O5" value="-0.019" spread="0.2202"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Monocytes Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.021" spread="0.2145"/>
                    <measurement group_id="O2" value="0.000" spread="0.1707"/>
                    <measurement group_id="O3" value="-0.013" spread="0.1399"/>
                    <measurement group_id="O4" value="-0.078" spread="0.2511"/>
                    <measurement group_id="O5" value="-0.077" spread="0.1709"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.200" spread="1.0959"/>
                    <measurement group_id="O2" value="-0.558" spread="0.9627"/>
                    <measurement group_id="O3" value="-0.693" spread="1.2971"/>
                    <measurement group_id="O4" value="-0.934" spread="1.4768"/>
                    <measurement group_id="O5" value="-0.325" spread="1.5720"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.026" spread="1.1945"/>
                    <measurement group_id="O2" value="-0.418" spread="1.1627"/>
                    <measurement group_id="O3" value="-0.337" spread="1.3109"/>
                    <measurement group_id="O4" value="-0.880" spread="1.8457"/>
                    <measurement group_id="O5" value="-0.537" spread="1.3989"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.102" spread="1.0044"/>
                    <measurement group_id="O2" value="-0.405" spread="1.1246"/>
                    <measurement group_id="O3" value="-0.290" spread="1.3463"/>
                    <measurement group_id="O4" value="-0.924" spread="1.9975"/>
                    <measurement group_id="O5" value="-0.732" spread="1.4028"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.249" spread="1.5358"/>
                    <measurement group_id="O2" value="-0.346" spread="1.2640"/>
                    <measurement group_id="O3" value="-0.256" spread="1.3898"/>
                    <measurement group_id="O4" value="-1.021" spread="1.7129"/>
                    <measurement group_id="O5" value="-0.717" spread="1.4589"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.117" spread="1.5103"/>
                    <measurement group_id="O2" value="-0.456" spread="1.1227"/>
                    <measurement group_id="O3" value="-0.458" spread="1.6879"/>
                    <measurement group_id="O4" value="-0.832" spread="2.2192"/>
                    <measurement group_id="O5" value="-0.673" spread="1.3887"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.490" spread="1.6866"/>
                    <measurement group_id="O2" value="-0.879" spread="1.5752"/>
                    <measurement group_id="O3" value="-0.617" spread="1.6027"/>
                    <measurement group_id="O4" value="-1.203" spread="2.2840"/>
                    <measurement group_id="O5" value="-0.448" spread="1.6816"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.972" spread="1.2085"/>
                    <measurement group_id="O2" value="-1.069" spread="1.4219"/>
                    <measurement group_id="O3" value="-0.595" spread="1.4319"/>
                    <measurement group_id="O4" value="-0.827" spread="2.2663"/>
                    <measurement group_id="O5" value="-0.618" spread="1.5716"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.210" spread="1.4067"/>
                    <measurement group_id="O2" value="-0.895" spread="1.6288"/>
                    <measurement group_id="O3" value="-0.593" spread="1.5309"/>
                    <measurement group_id="O4" value="-1.011" spread="2.2968"/>
                    <measurement group_id="O5" value="-0.850" spread="1.6461"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.774" spread="1.8189"/>
                    <measurement group_id="O2" value="-0.484" spread="2.2620"/>
                    <measurement group_id="O3" value="-0.555" spread="1.2608"/>
                    <measurement group_id="O4" value="-0.949" spread="1.7676"/>
                    <measurement group_id="O5" value="-0.568" spread="1.3889"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.869" spread="1.2796"/>
                    <measurement group_id="O2" value="-0.969" spread="1.8241"/>
                    <measurement group_id="O3" value="-0.433" spread="1.7889"/>
                    <measurement group_id="O4" value="-1.038" spread="2.4800"/>
                    <measurement group_id="O5" value="-0.718" spread="1.4299"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.722" spread="1.6422"/>
                    <measurement group_id="O2" value="-0.992" spread="1.6583"/>
                    <measurement group_id="O3" value="-0.541" spread="1.5519"/>
                    <measurement group_id="O4" value="-1.185" spread="2.1881"/>
                    <measurement group_id="O5" value="-0.354" spread="2.1441"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.006" spread="1.7393"/>
                    <measurement group_id="O2" value="-0.992" spread="1.4740"/>
                    <measurement group_id="O3" value="-0.575" spread="1.9567"/>
                    <measurement group_id="O4" value="-1.229" spread="2.4065"/>
                    <measurement group_id="O5" value="-0.495" spread="1.5857"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.978" spread="1.2444"/>
                    <measurement group_id="O2" value="-1.086" spread="1.6049"/>
                    <measurement group_id="O3" value="-0.717" spread="1.6966"/>
                    <measurement group_id="O4" value="-1.109" spread="2.2673"/>
                    <measurement group_id="O5" value="-0.983" spread="1.6556"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophils Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="32"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.861" spread="1.6858"/>
                    <measurement group_id="O2" value="-0.939" spread="1.5670"/>
                    <measurement group_id="O3" value="-0.558" spread="1.7944"/>
                    <measurement group_id="O4" value="-1.178" spread="2.6503"/>
                    <measurement group_id="O5" value="-0.805" spread="1.6631"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB) Concentration, Hemoglobin)</title>
        <description>Erythrocytes mean corpuscular hemoglobin (HGB) concentration and hemoglobin were measured in grams per liter (g/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB) Concentration, Hemoglobin)</title>
          <description>Erythrocytes mean corpuscular hemoglobin (HGB) concentration and hemoglobin were measured in grams per liter (g/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>g/L</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Ery. mean corpuscular HGB Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.293" spread="8.4594"/>
                    <measurement group_id="O2" value="0.789" spread="8.9719"/>
                    <measurement group_id="O3" value="-1.860" spread="8.0551"/>
                    <measurement group_id="O4" value="0.927" spread="9.1088"/>
                    <measurement group_id="O5" value="1.200" spread="12.2395"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.310" spread="7.9923"/>
                    <measurement group_id="O2" value="2.564" spread="9.8216"/>
                    <measurement group_id="O3" value="0.465" spread="8.4778"/>
                    <measurement group_id="O4" value="0.707" spread="8.6263"/>
                    <measurement group_id="O5" value="2.854" spread="10.1822"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.927" spread="10.0633"/>
                    <measurement group_id="O2" value="1.474" spread="10.5849"/>
                    <measurement group_id="O3" value="-2.500" spread="11.5045"/>
                    <measurement group_id="O4" value="-0.878" spread="9.4026"/>
                    <measurement group_id="O5" value="1.756" spread="11.8697"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.195" spread="11.7158"/>
                    <measurement group_id="O2" value="-1.897" spread="11.3249"/>
                    <measurement group_id="O3" value="-3.780" spread="10.7576"/>
                    <measurement group_id="O4" value="-3.079" spread="10.7033"/>
                    <measurement group_id="O5" value="0.610" spread="12.7493"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-7.927" spread="14.6704"/>
                    <measurement group_id="O2" value="-3.179" spread="13.4122"/>
                    <measurement group_id="O3" value="-3.907" spread="11.5404"/>
                    <measurement group_id="O4" value="-2.684" spread="9.4099"/>
                    <measurement group_id="O5" value="1.732" spread="13.3959"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.286" spread="12.3393"/>
                    <measurement group_id="O2" value="-3.000" spread="14.5751"/>
                    <measurement group_id="O3" value="-5.262" spread="12.1917"/>
                    <measurement group_id="O4" value="-1.026" spread="11.6816"/>
                    <measurement group_id="O5" value="-0.700" spread="16.1026"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.050" spread="12.8102"/>
                    <measurement group_id="O2" value="0.923" spread="11.8108"/>
                    <measurement group_id="O3" value="-1.902" spread="12.8078"/>
                    <measurement group_id="O4" value="0.919" spread="8.7349"/>
                    <measurement group_id="O5" value="0.200" spread="16.1725"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.000" spread="10.9232"/>
                    <measurement group_id="O2" value="4.132" spread="10.3849"/>
                    <measurement group_id="O3" value="-0.625" spread="14.6685"/>
                    <measurement group_id="O4" value="4.583" spread="11.3121"/>
                    <measurement group_id="O5" value="4.250" spread="13.4064"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.179" spread="10.3285"/>
                    <measurement group_id="O2" value="4.658" spread="9.6906"/>
                    <measurement group_id="O3" value="1.707" spread="9.9505"/>
                    <measurement group_id="O4" value="4.400" spread="13.7524"/>
                    <measurement group_id="O5" value="6.150" spread="12.5382"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.308" spread="9.7796"/>
                    <measurement group_id="O2" value="10.231" spread="9.5957"/>
                    <measurement group_id="O3" value="4.850" spread="11.3692"/>
                    <measurement group_id="O4" value="7.971" spread="12.3497"/>
                    <measurement group_id="O5" value="10.462" spread="12.9855"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.500" spread="9.7779"/>
                    <measurement group_id="O2" value="10.921" spread="10.2229"/>
                    <measurement group_id="O3" value="2.732" spread="12.4097"/>
                    <measurement group_id="O4" value="6.788" spread="12.2034"/>
                    <measurement group_id="O5" value="9.462" spread="12.7998"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.108" spread="9.8736"/>
                    <measurement group_id="O2" value="8.237" spread="12.0706"/>
                    <measurement group_id="O3" value="4.976" spread="11.5639"/>
                    <measurement group_id="O4" value="9.088" spread="11.5480"/>
                    <measurement group_id="O5" value="9.079" spread="11.5393"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.297" spread="10.6975"/>
                    <measurement group_id="O2" value="7.289" spread="12.6254"/>
                    <measurement group_id="O3" value="3.415" spread="12.6293"/>
                    <measurement group_id="O4" value="6.353" spread="14.3038"/>
                    <measurement group_id="O5" value="9.278" spread="12.8076"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Ery. mean corpuscular HGB Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.079" spread="10.4916"/>
                    <measurement group_id="O2" value="7.216" spread="9.3812"/>
                    <measurement group_id="O3" value="2.122" spread="11.8769"/>
                    <measurement group_id="O4" value="5.394" spread="12.9300"/>
                    <measurement group_id="O5" value="8.250" spread="11.3448"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.854" spread="5.6726"/>
                    <measurement group_id="O2" value="0.000" spread="5.6569"/>
                    <measurement group_id="O3" value="1.302" spread="5.1480"/>
                    <measurement group_id="O4" value="0.512" spread="6.0462"/>
                    <measurement group_id="O5" value="-0.875" spread="4.8368"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.810" spread="6.5154"/>
                    <measurement group_id="O2" value="-0.359" spread="5.2339"/>
                    <measurement group_id="O3" value="0.070" spread="6.5915"/>
                    <measurement group_id="O4" value="-1.561" spread="6.7047"/>
                    <measurement group_id="O5" value="0.317" spread="5.3499"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.390" spread="7.5162"/>
                    <measurement group_id="O2" value="0.895" spread="7.6434"/>
                    <measurement group_id="O3" value="0.881" spread="6.4551"/>
                    <measurement group_id="O4" value="0.512" spread="5.7189"/>
                    <measurement group_id="O5" value="1.195" spread="5.8916"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.561" spread="7.0995"/>
                    <measurement group_id="O2" value="0.308" spread="7.0865"/>
                    <measurement group_id="O3" value="2.195" spread="7.7628"/>
                    <measurement group_id="O4" value="0.553" spread="6.8010"/>
                    <measurement group_id="O5" value="1.195" spread="7.4439"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.220" spread="6.7879"/>
                    <measurement group_id="O2" value="0.692" spread="7.7601"/>
                    <measurement group_id="O3" value="2.488" spread="7.6512"/>
                    <measurement group_id="O4" value="0.868" spread="7.3344"/>
                    <measurement group_id="O5" value="2.488" spread="8.2344"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.619" spread="6.4768"/>
                    <measurement group_id="O2" value="2.579" spread="8.3880"/>
                    <measurement group_id="O3" value="1.524" spread="8.7853"/>
                    <measurement group_id="O4" value="1.737" spread="7.3547"/>
                    <measurement group_id="O5" value="3.125" spread="7.7400"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.400" spread="7.3233"/>
                    <measurement group_id="O2" value="2.667" spread="8.6764"/>
                    <measurement group_id="O3" value="2.268" spread="6.9822"/>
                    <measurement group_id="O4" value="1.892" spread="7.6186"/>
                    <measurement group_id="O5" value="2.925" spread="7.7207"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.564" spread="8.1879"/>
                    <measurement group_id="O2" value="3.658" spread="9.0622"/>
                    <measurement group_id="O3" value="4.075" spread="8.0714"/>
                    <measurement group_id="O4" value="2.000" spread="6.6462"/>
                    <measurement group_id="O5" value="3.425" spread="6.2834"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.513" spread="8.0259"/>
                    <measurement group_id="O2" value="3.342" spread="8.9511"/>
                    <measurement group_id="O3" value="3.122" spread="8.6261"/>
                    <measurement group_id="O4" value="0.857" spread="7.2645"/>
                    <measurement group_id="O5" value="3.400" spread="8.6730"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.282" spread="8.2684"/>
                    <measurement group_id="O2" value="4.487" spread="8.3094"/>
                    <measurement group_id="O3" value="4.300" spread="9.4032"/>
                    <measurement group_id="O4" value="2.118" spread="7.4254"/>
                    <measurement group_id="O5" value="5.615" spread="8.6378"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.947" spread="9.1738"/>
                    <measurement group_id="O2" value="6.053" spread="8.1405"/>
                    <measurement group_id="O3" value="4.293" spread="9.5766"/>
                    <measurement group_id="O4" value="3.818" spread="7.3334"/>
                    <measurement group_id="O5" value="4.949" spread="8.4851"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.432" spread="9.1090"/>
                    <measurement group_id="O2" value="5.868" spread="8.7863"/>
                    <measurement group_id="O3" value="4.317" spread="9.6552"/>
                    <measurement group_id="O4" value="3.618" spread="7.8277"/>
                    <measurement group_id="O5" value="4.132" spread="7.7987"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.486" spread="10.1040"/>
                    <measurement group_id="O2" value="5.000" spread="9.2998"/>
                    <measurement group_id="O3" value="3.659" spread="9.1750"/>
                    <measurement group_id="O4" value="4.912" spread="8.5895"/>
                    <measurement group_id="O5" value="4.722" spread="8.5511"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hemoglobin Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.474" spread="9.7002"/>
                    <measurement group_id="O2" value="5.270" spread="9.1974"/>
                    <measurement group_id="O3" value="3.780" spread="9.9210"/>
                    <measurement group_id="O4" value="4.030" spread="9.2550"/>
                    <measurement group_id="O5" value="4.725" spread="7.3554"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB))</title>
        <description>Erythrocytes mean corpuscular hemoglobin (HGB) was measured in picograms (pg).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB))</title>
          <description>Erythrocytes mean corpuscular hemoglobin (HGB) was measured in picograms (pg).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>picograms (pg)</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.073" spread="0.4980"/>
                    <measurement group_id="O2" value="0.058" spread="0.4624"/>
                    <measurement group_id="O3" value="-0.049" spread="0.4050"/>
                    <measurement group_id="O4" value="0.073" spread="0.3975"/>
                    <measurement group_id="O5" value="-0.055" spread="0.4455"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.050" spread="0.3890"/>
                    <measurement group_id="O2" value="0.126" spread="0.5149"/>
                    <measurement group_id="O3" value="0.023" spread="0.4225"/>
                    <measurement group_id="O4" value="0.066" spread="0.4357"/>
                    <measurement group_id="O5" value="0.085" spread="0.4287"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.112" spread="0.5501"/>
                    <measurement group_id="O2" value="0.089" spread="0.5584"/>
                    <measurement group_id="O3" value="0.060" spread="0.5910"/>
                    <measurement group_id="O4" value="0.012" spread="0.4691"/>
                    <measurement group_id="O5" value="0.066" spread="0.6085"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.110" spread="0.6778"/>
                    <measurement group_id="O2" value="0.141" spread="0.6801"/>
                    <measurement group_id="O3" value="0.007" spread="0.5926"/>
                    <measurement group_id="O4" value="0.034" spread="0.6851"/>
                    <measurement group_id="O5" value="0.095" spread="0.7994"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.285" spread="0.6770"/>
                    <measurement group_id="O2" value="0.023" spread="0.7253"/>
                    <measurement group_id="O3" value="0.091" spread="0.8358"/>
                    <measurement group_id="O4" value="-0.132" spread="0.8335"/>
                    <measurement group_id="O5" value="0.039" spread="1.0454"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.233" spread="0.7281"/>
                    <measurement group_id="O2" value="0.097" spread="0.8824"/>
                    <measurement group_id="O3" value="0.014" spread="0.9236"/>
                    <measurement group_id="O4" value="-0.118" spread="0.8440"/>
                    <measurement group_id="O5" value="-0.067" spread="1.1713"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.290" spread="0.8145"/>
                    <measurement group_id="O2" value="-0.033" spread="0.9172"/>
                    <measurement group_id="O3" value="0.029" spread="0.9819"/>
                    <measurement group_id="O4" value="-0.035" spread="0.7013"/>
                    <measurement group_id="O5" value="0.075" spread="1.0824"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.249" spread="1.0443"/>
                    <measurement group_id="O2" value="0.108" spread="0.9947"/>
                    <measurement group_id="O3" value="-0.057" spread="1.1804"/>
                    <measurement group_id="O4" value="-0.097" spread="0.7284"/>
                    <measurement group_id="O5" value="-0.007" spread="1.2338"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.103" spread="1.0101"/>
                    <measurement group_id="O2" value="0.029" spread="0.7241"/>
                    <measurement group_id="O3" value="-0.122" spread="1.1130"/>
                    <measurement group_id="O4" value="-0.211" spread="0.8277"/>
                    <measurement group_id="O5" value="0.020" spread="1.2950"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.003" spread="1.2619"/>
                    <measurement group_id="O2" value="0.297" spread="0.8561"/>
                    <measurement group_id="O3" value="0.058" spread="1.1522"/>
                    <measurement group_id="O4" value="0.026" spread="0.7684"/>
                    <measurement group_id="O5" value="0.167" spread="1.2472"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.082" spread="1.3242"/>
                    <measurement group_id="O2" value="0.237" spread="0.8722"/>
                    <measurement group_id="O3" value="-0.093" spread="1.0792"/>
                    <measurement group_id="O4" value="-0.248" spread="0.8581"/>
                    <measurement group_id="O5" value="0.118" spread="1.1473"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.170" spread="1.3453"/>
                    <measurement group_id="O2" value="0.134" spread="0.8960"/>
                    <measurement group_id="O3" value="-0.134" spread="1.2095"/>
                    <measurement group_id="O4" value="-0.147" spread="0.8645"/>
                    <measurement group_id="O5" value="0.034" spread="1.0839"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.097" spread="1.3103"/>
                    <measurement group_id="O2" value="0.129" spread="0.8742"/>
                    <measurement group_id="O3" value="-0.080" spread="1.1771"/>
                    <measurement group_id="O4" value="-0.159" spread="0.7480"/>
                    <measurement group_id="O5" value="0.108" spread="1.2532"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.137" spread="1.4139"/>
                    <measurement group_id="O2" value="0.178" spread="0.9369"/>
                    <measurement group_id="O3" value="-0.120" spread="1.1279"/>
                    <measurement group_id="O4" value="-0.030" spread="0.7888"/>
                    <measurement group_id="O5" value="0.140" spread="1.2161"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Volume)</title>
        <description>Erythrocytes mean corpuscular volume was measured in femtolitres (fL).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Volume)</title>
          <description>Erythrocytes mean corpuscular volume was measured in femtolitres (fL).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>femtolitres (fL)</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.422" spread="1.8855"/>
                    <measurement group_id="O2" value="-0.087" spread="1.9540"/>
                    <measurement group_id="O3" value="0.386" spread="2.2542"/>
                    <measurement group_id="O4" value="-0.017" spread="2.1066"/>
                    <measurement group_id="O5" value="-0.510" spread="2.7686"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.450" spread="1.8867"/>
                    <measurement group_id="O2" value="-0.362" spread="2.1689"/>
                    <measurement group_id="O3" value="-0.021" spread="1.8767"/>
                    <measurement group_id="O4" value="-0.039" spread="2.3876"/>
                    <measurement group_id="O5" value="-0.549" spread="2.5751"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.829" spread="2.3409"/>
                    <measurement group_id="O2" value="-0.163" spread="2.4631"/>
                    <measurement group_id="O3" value="0.945" spread="3.2325"/>
                    <measurement group_id="O4" value="0.354" spread="2.8851"/>
                    <measurement group_id="O5" value="-0.259" spread="2.5328"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.163" spread="3.6524"/>
                    <measurement group_id="O2" value="0.938" spread="2.9445"/>
                    <measurement group_id="O3" value="1.110" spread="3.0283"/>
                    <measurement group_id="O4" value="0.916" spread="3.0058"/>
                    <measurement group_id="O5" value="0.090" spread="3.5125"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.478" spread="3.9560"/>
                    <measurement group_id="O2" value="0.951" spread="3.4617"/>
                    <measurement group_id="O3" value="1.367" spread="3.8471"/>
                    <measurement group_id="O4" value="0.342" spread="3.1129"/>
                    <measurement group_id="O5" value="-0.390" spread="3.3907"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.107" spread="3.4022"/>
                    <measurement group_id="O2" value="1.168" spread="3.7760"/>
                    <measurement group_id="O3" value="1.571" spread="4.3326"/>
                    <measurement group_id="O4" value="-0.016" spread="3.6944"/>
                    <measurement group_id="O5" value="0.048" spread="4.4345"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.497" spread="3.5197"/>
                    <measurement group_id="O2" value="-0.349" spread="2.8975"/>
                    <measurement group_id="O3" value="0.649" spread="3.7758"/>
                    <measurement group_id="O4" value="-0.338" spread="2.5959"/>
                    <measurement group_id="O5" value="0.202" spread="4.2993"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.033" spread="2.9007"/>
                    <measurement group_id="O2" value="-0.858" spread="2.1793"/>
                    <measurement group_id="O3" value="0.143" spread="4.9985"/>
                    <measurement group_id="O4" value="-1.522" spread="3.1692"/>
                    <measurement group_id="O5" value="-1.195" spread="3.5759"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.910" spread="2.6477"/>
                    <measurement group_id="O2" value="-1.184" spread="2.3264"/>
                    <measurement group_id="O3" value="-0.754" spread="3.3662"/>
                    <measurement group_id="O4" value="-1.854" spread="3.6605"/>
                    <measurement group_id="O5" value="-1.638" spread="3.3447"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.654" spread="2.7565"/>
                    <measurement group_id="O2" value="-1.851" spread="2.4024"/>
                    <measurement group_id="O3" value="-1.075" spread="3.5390"/>
                    <measurement group_id="O4" value="-2.071" spread="3.7652"/>
                    <measurement group_id="O5" value="-2.351" spread="3.1052"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.724" spread="3.1037"/>
                    <measurement group_id="O2" value="-2.266" spread="2.3516"/>
                    <measurement group_id="O3" value="-0.912" spread="3.9627"/>
                    <measurement group_id="O4" value="-2.558" spread="3.8468"/>
                    <measurement group_id="O5" value="-2.236" spread="3.2869"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.386" spread="2.8575"/>
                    <measurement group_id="O2" value="-1.882" spread="3.1285"/>
                    <measurement group_id="O3" value="-1.698" spread="3.0263"/>
                    <measurement group_id="O4" value="-2.885" spread="3.1443"/>
                    <measurement group_id="O5" value="-2.421" spread="2.9445"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.405" spread="3.4627"/>
                    <measurement group_id="O2" value="-1.632" spread="3.4207"/>
                    <measurement group_id="O3" value="-1.117" spread="3.4616"/>
                    <measurement group_id="O4" value="-2.171" spread="4.4367"/>
                    <measurement group_id="O5" value="-2.186" spread="3.4915"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.942" spread="3.5913"/>
                    <measurement group_id="O2" value="-1.492" spread="2.5065"/>
                    <measurement group_id="O3" value="-0.846" spread="3.1243"/>
                    <measurement group_id="O4" value="-1.527" spread="3.6540"/>
                    <measurement group_id="O5" value="-1.788" spread="3.5554"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes)</title>
        <description>Erythrocytes was measured in number of red blood cells per liter (10^12/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Erythrocytes)</title>
          <description>Erythrocytes was measured in number of red blood cells per liter (10^12/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>10^12 red blood cells per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.148" spread="0.2071"/>
                    <measurement group_id="O2" value="-0.008" spread="0.1927"/>
                    <measurement group_id="O3" value="0.050" spread="0.1773"/>
                    <measurement group_id="O4" value="0.008" spread="0.2109"/>
                    <measurement group_id="O5" value="-0.017" spread="0.1609"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.149" spread="0.2244"/>
                    <measurement group_id="O2" value="-0.029" spread="0.1788"/>
                    <measurement group_id="O3" value="-0.004" spread="0.2280"/>
                    <measurement group_id="O4" value="-0.063" spread="0.2236"/>
                    <measurement group_id="O5" value="0.000" spread="0.1809"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.132" spread="0.2780"/>
                    <measurement group_id="O2" value="0.018" spread="0.2535"/>
                    <measurement group_id="O3" value="0.023" spread="0.2135"/>
                    <measurement group_id="O4" value="0.013" spread="0.1955"/>
                    <measurement group_id="O5" value="0.031" spread="0.2065"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.135" spread="0.2546"/>
                    <measurement group_id="O2" value="-0.011" spread="0.2206"/>
                    <measurement group_id="O3" value="0.074" spread="0.2466"/>
                    <measurement group_id="O4" value="0.014" spread="0.2190"/>
                    <measurement group_id="O5" value="0.026" spread="0.2264"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.131" spread="0.2678"/>
                    <measurement group_id="O2" value="0.021" spread="0.2561"/>
                    <measurement group_id="O3" value="0.069" spread="0.2419"/>
                    <measurement group_id="O4" value="0.051" spread="0.2243"/>
                    <measurement group_id="O5" value="0.075" spread="0.2393"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.020" spread="0.2375"/>
                    <measurement group_id="O2" value="0.075" spread="0.2898"/>
                    <measurement group_id="O3" value="0.047" spread="0.2810"/>
                    <measurement group_id="O4" value="0.074" spread="0.2255"/>
                    <measurement group_id="O5" value="0.110" spread="0.2533"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.036" spread="0.2618"/>
                    <measurement group_id="O2" value="0.096" spread="0.2855"/>
                    <measurement group_id="O3" value="0.068" spread="0.2089"/>
                    <measurement group_id="O4" value="0.064" spread="0.2273"/>
                    <measurement group_id="O5" value="0.081" spread="0.2191"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.059" spread="0.2639"/>
                    <measurement group_id="O2" value="0.110" spread="0.2974"/>
                    <measurement group_id="O3" value="0.142" spread="0.2573"/>
                    <measurement group_id="O4" value="0.074" spread="0.2250"/>
                    <measurement group_id="O5" value="0.110" spread="0.1931"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.034" spread="0.2453"/>
                    <measurement group_id="O2" value="0.108" spread="0.2681"/>
                    <measurement group_id="O3" value="0.122" spread="0.2445"/>
                    <measurement group_id="O4" value="0.058" spread="0.2359"/>
                    <measurement group_id="O5" value="0.106" spread="0.2567"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.2461"/>
                    <measurement group_id="O2" value="0.104" spread="0.2660"/>
                    <measurement group_id="O3" value="0.133" spread="0.2716"/>
                    <measurement group_id="O4" value="0.061" spread="0.2555"/>
                    <measurement group_id="O5" value="0.156" spread="0.2714"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.044" spread="0.2524"/>
                    <measurement group_id="O2" value="0.166" spread="0.2542"/>
                    <measurement group_id="O3" value="0.156" spread="0.2849"/>
                    <measurement group_id="O4" value="0.161" spread="0.2399"/>
                    <measurement group_id="O5" value="0.145" spread="0.2377"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.079" spread="0.2682"/>
                    <measurement group_id="O2" value="0.177" spread="0.2733"/>
                    <measurement group_id="O3" value="0.163" spread="0.2736"/>
                    <measurement group_id="O4" value="0.141" spread="0.2535"/>
                    <measurement group_id="O5" value="0.129" spread="0.2403"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.035" spread="0.2645"/>
                    <measurement group_id="O2" value="0.146" spread="0.2846"/>
                    <measurement group_id="O3" value="0.133" spread="0.2622"/>
                    <measurement group_id="O4" value="0.188" spread="0.2933"/>
                    <measurement group_id="O5" value="0.135" spread="0.2128"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.061" spread="0.2693"/>
                    <measurement group_id="O2" value="0.146" spread="0.2994"/>
                    <measurement group_id="O3" value="0.141" spread="0.2747"/>
                    <measurement group_id="O4" value="0.135" spread="0.2934"/>
                    <measurement group_id="O5" value="0.129" spread="0.2354"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Hematocrit)</title>
        <description>Hematocrit was measured in volume percentage (%) of red blood cells in blood.</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Hematocrit)</title>
          <description>Hematocrit was measured in volume percentage (%) of red blood cells in blood.</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>volume % of red blood cells</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.011" spread="0.0189"/>
                    <measurement group_id="O2" value="-0.001" spread="0.0211"/>
                    <measurement group_id="O3" value="0.007" spread="0.0181"/>
                    <measurement group_id="O4" value="0.000" spread="0.0206"/>
                    <measurement group_id="O5" value="-0.004" spread="0.0206"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.011" spread="0.0230"/>
                    <measurement group_id="O2" value="-0.004" spread="0.0204"/>
                    <measurement group_id="O3" value="-0.000" spread="0.0205"/>
                    <measurement group_id="O4" value="-0.006" spread="0.0220"/>
                    <measurement group_id="O5" value="-0.003" spread="0.0174"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.008" spread="0.0254"/>
                    <measurement group_id="O2" value="0.001" spread="0.0211"/>
                    <measurement group_id="O3" value="0.006" spread="0.0220"/>
                    <measurement group_id="O4" value="0.003" spread="0.0190"/>
                    <measurement group_id="O5" value="0.001" spread="0.0209"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="0.0239"/>
                    <measurement group_id="O2" value="0.003" spread="0.0244"/>
                    <measurement group_id="O3" value="0.012" spread="0.0237"/>
                    <measurement group_id="O4" value="0.005" spread="0.0208"/>
                    <measurement group_id="O5" value="0.003" spread="0.0232"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.005" spread="0.0287"/>
                    <measurement group_id="O2" value="0.007" spread="0.0281"/>
                    <measurement group_id="O3" value="0.013" spread="0.0276"/>
                    <measurement group_id="O4" value="0.006" spread="0.0219"/>
                    <measurement group_id="O5" value="0.005" spread="0.0231"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.004" spread="0.0202"/>
                    <measurement group_id="O2" value="0.012" spread="0.0259"/>
                    <measurement group_id="O3" value="0.011" spread="0.0254"/>
                    <measurement group_id="O4" value="0.006" spread="0.0240"/>
                    <measurement group_id="O5" value="0.010" spread="0.0252"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.006" spread="0.0217"/>
                    <measurement group_id="O2" value="0.007" spread="0.0270"/>
                    <measurement group_id="O3" value="0.010" spread="0.0211"/>
                    <measurement group_id="O4" value="0.004" spread="0.0241"/>
                    <measurement group_id="O5" value="0.008" spread="0.0246"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.001" spread="0.0192"/>
                    <measurement group_id="O2" value="0.006" spread="0.0253"/>
                    <measurement group_id="O3" value="0.014" spread="0.0256"/>
                    <measurement group_id="O4" value="-0.000" spread="0.0222"/>
                    <measurement group_id="O5" value="0.005" spread="0.0219"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="0.0210"/>
                    <measurement group_id="O2" value="0.004" spread="0.0248"/>
                    <measurement group_id="O3" value="0.008" spread="0.0241"/>
                    <measurement group_id="O4" value="-0.003" spread="0.0229"/>
                    <measurement group_id="O5" value="0.002" spread="0.0238"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.009" spread="0.0207"/>
                    <measurement group_id="O2" value="0.000" spread="0.0249"/>
                    <measurement group_id="O3" value="0.007" spread="0.0225"/>
                    <measurement group_id="O4" value="-0.004" spread="0.0196"/>
                    <measurement group_id="O5" value="0.003" spread="0.0248"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.0222"/>
                    <measurement group_id="O2" value="0.004" spread="0.0228"/>
                    <measurement group_id="O3" value="0.009" spread="0.0258"/>
                    <measurement group_id="O4" value="0.003" spread="0.0221"/>
                    <measurement group_id="O5" value="0.003" spread="0.0234"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0231"/>
                    <measurement group_id="O2" value="0.007" spread="0.0278"/>
                    <measurement group_id="O3" value="0.007" spread="0.0246"/>
                    <measurement group_id="O4" value="-0.001" spread="0.0221"/>
                    <measurement group_id="O5" value="0.000" spread="0.0206"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.003" spread="0.0272"/>
                    <measurement group_id="O2" value="0.006" spread="0.0297"/>
                    <measurement group_id="O3" value="0.007" spread="0.0239"/>
                    <measurement group_id="O4" value="0.007" spread="0.0246"/>
                    <measurement group_id="O5" value="0.002" spread="0.0194"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.001" spread="0.0243"/>
                    <measurement group_id="O2" value="0.007" spread="0.0257"/>
                    <measurement group_id="O3" value="0.009" spread="0.0260"/>
                    <measurement group_id="O4" value="0.005" spread="0.0252"/>
                    <measurement group_id="O5" value="0.004" spread="0.0212"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Hematology Parameters During the Study (Platelets)</title>
        <description>Platelets was measured in number of platelets per liter (10^9/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Hematology Parameters During the Study (Platelets)</title>
          <description>Platelets was measured in number of platelets per liter (10^9/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>10^9 platelets per liter</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.073" spread="30.2609"/>
                    <measurement group_id="O2" value="-3.368" spread="25.9515"/>
                    <measurement group_id="O3" value="3.209" spread="30.5883"/>
                    <measurement group_id="O4" value="-2.098" spread="24.6412"/>
                    <measurement group_id="O5" value="-9.325" spread="23.4109"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.000" spread="27.3112"/>
                    <measurement group_id="O2" value="-5.179" spread="38.2800"/>
                    <measurement group_id="O3" value="-3.810" spread="41.8250"/>
                    <measurement group_id="O4" value="-15.122" spread="32.8414"/>
                    <measurement group_id="O5" value="-15.415" spread="31.7025"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.927" spread="29.6643"/>
                    <measurement group_id="O2" value="-6.868" spread="29.7487"/>
                    <measurement group_id="O3" value="-13.878" spread="43.7568"/>
                    <measurement group_id="O4" value="-19.415" spread="32.6450"/>
                    <measurement group_id="O5" value="-27.073" spread="41.9299"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.561" spread="29.1042"/>
                    <measurement group_id="O2" value="-12.077" spread="28.9876"/>
                    <measurement group_id="O3" value="-5.475" spread="44.7718"/>
                    <measurement group_id="O4" value="-17.605" spread="29.8442"/>
                    <measurement group_id="O5" value="-26.195" spread="44.1719"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.171" spread="32.0795"/>
                    <measurement group_id="O2" value="-17.359" spread="35.4308"/>
                    <measurement group_id="O3" value="-11.286" spread="40.7451"/>
                    <measurement group_id="O4" value="-10.079" spread="44.8977"/>
                    <measurement group_id="O5" value="-23.171" spread="47.2995"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-18.833" spread="50.4844"/>
                    <measurement group_id="O2" value="-18.263" spread="37.3259"/>
                    <measurement group_id="O3" value="-13.952" spread="50.7173"/>
                    <measurement group_id="O4" value="-9.895" spread="35.3246"/>
                    <measurement group_id="O5" value="-25.425" spread="37.6556"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-18.625" spread="50.3988"/>
                    <measurement group_id="O2" value="-23.077" spread="39.6534"/>
                    <measurement group_id="O3" value="-10.512" spread="48.0755"/>
                    <measurement group_id="O4" value="-15.324" spread="28.8329"/>
                    <measurement group_id="O5" value="-22.725" spread="42.2502"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-19.974" spread="49.0196"/>
                    <measurement group_id="O2" value="-14.000" spread="37.7760"/>
                    <measurement group_id="O3" value="-4.600" spread="49.4025"/>
                    <measurement group_id="O4" value="-10.972" spread="36.8375"/>
                    <measurement group_id="O5" value="-22.900" spread="47.4092"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-24.256" spread="51.8001"/>
                    <measurement group_id="O2" value="-16.868" spread="40.6635"/>
                    <measurement group_id="O3" value="-7.683" spread="47.8155"/>
                    <measurement group_id="O4" value="-12.800" spread="30.7904"/>
                    <measurement group_id="O5" value="-19.600" spread="42.3052"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-22.410" spread="51.9553"/>
                    <measurement group_id="O2" value="-18.590" spread="41.7226"/>
                    <measurement group_id="O3" value="-13.575" spread="51.9304"/>
                    <measurement group_id="O4" value="-20.618" spread="38.8969"/>
                    <measurement group_id="O5" value="-23.179" spread="42.2018"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-25.000" spread="52.6990"/>
                    <measurement group_id="O2" value="-16.474" spread="46.8844"/>
                    <measurement group_id="O3" value="-14.561" spread="50.2106"/>
                    <measurement group_id="O4" value="-18.848" spread="40.0563"/>
                    <measurement group_id="O5" value="-23.846" spread="45.1340"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-23.432" spread="53.2747"/>
                    <measurement group_id="O2" value="-20.895" spread="41.4845"/>
                    <measurement group_id="O3" value="-14.927" spread="51.2652"/>
                    <measurement group_id="O4" value="-24.088" spread="33.4133"/>
                    <measurement group_id="O5" value="-21.789" spread="46.1467"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="36"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-22.703" spread="57.8383"/>
                    <measurement group_id="O2" value="-22.474" spread="41.0627"/>
                    <measurement group_id="O3" value="-18.051" spread="49.1646"/>
                    <measurement group_id="O4" value="-24.735" spread="38.4710"/>
                    <measurement group_id="O5" value="-31.389" spread="48.5306"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-27.395" spread="56.2963"/>
                    <measurement group_id="O2" value="-23.811" spread="47.1150"/>
                    <measurement group_id="O3" value="-24.220" spread="46.2458"/>
                    <measurement group_id="O4" value="-22.273" spread="37.4243"/>
                    <measurement group_id="O5" value="-28.974" spread="42.9960"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Biochemistry Parameters During the Study (Alanine Aminotransferase, Alkaline Phosphatase, Aspartate Aminotransferase, Gamma Glutamyl Transferase, Lactate Dehydrogenase)</title>
        <description>Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, gamma glutamyl transferase, lactate dehydrogenase were measured in units per liter (U/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Biochemistry Parameters During the Study (Alanine Aminotransferase, Alkaline Phosphatase, Aspartate Aminotransferase, Gamma Glutamyl Transferase, Lactate Dehydrogenase)</title>
          <description>Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, gamma glutamyl transferase, lactate dehydrogenase were measured in units per liter (U/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>U/L</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Alanine Aminotransferase Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.366" spread="12.7451"/>
                    <measurement group_id="O2" value="2.526" spread="15.5211"/>
                    <measurement group_id="O3" value="2.628" spread="42.1234"/>
                    <measurement group_id="O4" value="3.122" spread="10.2791"/>
                    <measurement group_id="O5" value="0.700" spread="9.5868"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.714" spread="15.4624"/>
                    <measurement group_id="O2" value="2.026" spread="8.9428"/>
                    <measurement group_id="O3" value="-1.047" spread="41.1223"/>
                    <measurement group_id="O4" value="4.927" spread="20.9623"/>
                    <measurement group_id="O5" value="1.171" spread="10.2978"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.854" spread="15.1897"/>
                    <measurement group_id="O2" value="1.553" spread="16.2758"/>
                    <measurement group_id="O3" value="-3.952" spread="38.9546"/>
                    <measurement group_id="O4" value="22.756" spread="139.8531"/>
                    <measurement group_id="O5" value="-1.561" spread="10.1392"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.707" spread="13.6478"/>
                    <measurement group_id="O2" value="-1.385" spread="9.4580"/>
                    <measurement group_id="O3" value="5.465" spread="68.0764"/>
                    <measurement group_id="O4" value="0.795" spread="11.4321"/>
                    <measurement group_id="O5" value="-1.659" spread="11.1009"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.220" spread="15.1765"/>
                    <measurement group_id="O2" value="0.359" spread="12.2356"/>
                    <measurement group_id="O3" value="-4.429" spread="38.1756"/>
                    <measurement group_id="O4" value="1.184" spread="13.0692"/>
                    <measurement group_id="O5" value="-1.390" spread="8.1941"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.048" spread="18.0026"/>
                    <measurement group_id="O2" value="2.684" spread="16.3229"/>
                    <measurement group_id="O3" value="-4.857" spread="38.6211"/>
                    <measurement group_id="O4" value="0.579" spread="12.9273"/>
                    <measurement group_id="O5" value="0.829" spread="11.5432"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.300" spread="39.9482"/>
                    <measurement group_id="O2" value="3.821" spread="13.0139"/>
                    <measurement group_id="O3" value="-4.881" spread="39.1808"/>
                    <measurement group_id="O4" value="-0.838" spread="11.1118"/>
                    <measurement group_id="O5" value="-1.350" spread="10.5479"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.564" spread="19.4974"/>
                    <measurement group_id="O2" value="2.789" spread="14.5475"/>
                    <measurement group_id="O3" value="-5.659" spread="39.6652"/>
                    <measurement group_id="O4" value="1.528" spread="11.0259"/>
                    <measurement group_id="O5" value="-3.475" spread="8.6202"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.385" spread="17.7373"/>
                    <measurement group_id="O2" value="2.658" spread="12.8174"/>
                    <measurement group_id="O3" value="-3.244" spread="43.4688"/>
                    <measurement group_id="O4" value="-0.171" spread="8.7228"/>
                    <measurement group_id="O5" value="-2.775" spread="10.4280"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-4.487" spread="16.5400"/>
                    <measurement group_id="O2" value="2.385" spread="12.8956"/>
                    <measurement group_id="O3" value="-4.150" spread="44.0126"/>
                    <measurement group_id="O4" value="-2.176" spread="12.7742"/>
                    <measurement group_id="O5" value="-0.821" spread="11.5482"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.579" spread="10.5411"/>
                    <measurement group_id="O2" value="0.184" spread="11.8660"/>
                    <measurement group_id="O3" value="-2.976" spread="42.9275"/>
                    <measurement group_id="O4" value="-0.471" spread="11.2848"/>
                    <measurement group_id="O5" value="-1.103" spread="10.6296"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.622" spread="10.2506"/>
                    <measurement group_id="O2" value="0.816" spread="12.6680"/>
                    <measurement group_id="O3" value="-2.780" spread="44.9719"/>
                    <measurement group_id="O4" value="-3.853" spread="11.1059"/>
                    <measurement group_id="O5" value="-1.385" spread="13.1061"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.649" spread="19.7993"/>
                    <measurement group_id="O2" value="1.474" spread="13.1514"/>
                    <measurement group_id="O3" value="-3.415" spread="43.2966"/>
                    <measurement group_id="O4" value="-3.882" spread="12.8741"/>
                    <measurement group_id="O5" value="-2.692" spread="10.2525"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine Aminotransferase Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.605" spread="14.0646"/>
                    <measurement group_id="O2" value="2.216" spread="12.8542"/>
                    <measurement group_id="O3" value="-4.561" spread="43.1926"/>
                    <measurement group_id="O4" value="-3.794" spread="13.1628"/>
                    <measurement group_id="O5" value="-0.575" spread="9.6181"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.098" spread="6.0034"/>
                    <measurement group_id="O2" value="-1.342" spread="8.0983"/>
                    <measurement group_id="O3" value="-2.721" spread="7.2056"/>
                    <measurement group_id="O4" value="-3.244" spread="4.9989"/>
                    <measurement group_id="O5" value="-4.275" spread="7.1360"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.905" spread="6.7960"/>
                    <measurement group_id="O2" value="-3.282" spread="7.8370"/>
                    <measurement group_id="O3" value="-4.349" spread="9.5963"/>
                    <measurement group_id="O4" value="-4.805" spread="7.8237"/>
                    <measurement group_id="O5" value="-3.585" spread="8.8430"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.634" spread="9.0630"/>
                    <measurement group_id="O2" value="-1.077" spread="10.4236"/>
                    <measurement group_id="O3" value="-3.262" spread="9.9144"/>
                    <measurement group_id="O4" value="-1.439" spread="18.3508"/>
                    <measurement group_id="O5" value="-4.829" spread="10.9268"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.220" spread="8.3711"/>
                    <measurement group_id="O2" value="0.308" spread="12.6515"/>
                    <measurement group_id="O3" value="1.233" spread="37.8014"/>
                    <measurement group_id="O4" value="-5.026" spread="10.2019"/>
                    <measurement group_id="O5" value="-3.585" spread="9.8336"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.463" spread="8.8122"/>
                    <measurement group_id="O2" value="-0.462" spread="12.1066"/>
                    <measurement group_id="O3" value="-5.952" spread="11.0695"/>
                    <measurement group_id="O4" value="-4.947" spread="12.0538"/>
                    <measurement group_id="O5" value="-3.146" spread="17.2476"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-8.357" spread="12.7276"/>
                    <measurement group_id="O2" value="-0.895" spread="13.1515"/>
                    <measurement group_id="O3" value="-7.238" spread="10.7722"/>
                    <measurement group_id="O4" value="-4.605" spread="11.6539"/>
                    <measurement group_id="O5" value="-1.512" spread="25.7722"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-10.425" spread="14.0510"/>
                    <measurement group_id="O2" value="-5.410" spread="15.1895"/>
                    <measurement group_id="O3" value="-10.143" spread="13.0264"/>
                    <measurement group_id="O4" value="-7.027" spread="11.8544"/>
                    <measurement group_id="O5" value="-6.650" spread="14.8143"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-12.795" spread="15.4752"/>
                    <measurement group_id="O2" value="-4.769" spread="13.8097"/>
                    <measurement group_id="O3" value="-9.463" spread="11.3448"/>
                    <measurement group_id="O4" value="-6.361" spread="12.7843"/>
                    <measurement group_id="O5" value="-7.225" spread="18.4231"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-12.795" spread="16.9351"/>
                    <measurement group_id="O2" value="-5.684" spread="15.7259"/>
                    <measurement group_id="O3" value="-11.244" spread="12.6249"/>
                    <measurement group_id="O4" value="-8.314" spread="10.9054"/>
                    <measurement group_id="O5" value="-8.525" spread="16.8523"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-13.667" spread="16.1870"/>
                    <measurement group_id="O2" value="-4.769" spread="16.1530"/>
                    <measurement group_id="O3" value="-10.900" spread="13.0026"/>
                    <measurement group_id="O4" value="-9.118" spread="12.5765"/>
                    <measurement group_id="O5" value="-8.385" spread="17.5988"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-11.816" spread="19.2436"/>
                    <measurement group_id="O2" value="-6.368" spread="15.4735"/>
                    <measurement group_id="O3" value="-11.122" spread="12.3495"/>
                    <measurement group_id="O4" value="-8.059" spread="9.5217"/>
                    <measurement group_id="O5" value="-6.487" spread="19.2434"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-11.000" spread="16.9706"/>
                    <measurement group_id="O2" value="-5.658" spread="15.7485"/>
                    <measurement group_id="O3" value="-11.024" spread="12.9180"/>
                    <measurement group_id="O4" value="-10.559" spread="11.6987"/>
                    <measurement group_id="O5" value="-8.175" spread="17.8884"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-12.622" spread="17.6373"/>
                    <measurement group_id="O2" value="-6.421" spread="14.9099"/>
                    <measurement group_id="O3" value="-10.537" spread="13.5759"/>
                    <measurement group_id="O4" value="-8.647" spread="10.5483"/>
                    <measurement group_id="O5" value="-8.950" spread="18.3162"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alkaline Phosphatase Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-12.211" spread="19.0379"/>
                    <measurement group_id="O2" value="-6.500" spread="16.5313"/>
                    <measurement group_id="O3" value="-11.049" spread="14.4827"/>
                    <measurement group_id="O4" value="-7.765" spread="12.3290"/>
                    <measurement group_id="O5" value="-7.875" spread="20.1370"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.854" spread="10.3212"/>
                    <measurement group_id="O2" value="1.447" spread="6.2155"/>
                    <measurement group_id="O3" value="-0.023" spread="27.5409"/>
                    <measurement group_id="O4" value="2.244" spread="6.7889"/>
                    <measurement group_id="O5" value="0.475" spread="5.2963"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.762" spread="10.5294"/>
                    <measurement group_id="O2" value="0.487" spread="4.0967"/>
                    <measurement group_id="O3" value="-2.233" spread="26.3266"/>
                    <measurement group_id="O4" value="3.805" spread="14.7635"/>
                    <measurement group_id="O5" value="0.780" spread="6.1746"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.976" spread="10.6642"/>
                    <measurement group_id="O2" value="1.289" spread="7.5584"/>
                    <measurement group_id="O3" value="-3.262" spread="25.1047"/>
                    <measurement group_id="O4" value="8.927" spread="52.0660"/>
                    <measurement group_id="O5" value="-1.195" spread="4.2791"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.537" spread="10.5477"/>
                    <measurement group_id="O2" value="-0.077" spread="5.8687"/>
                    <measurement group_id="O3" value="2.279" spread="34.7805"/>
                    <measurement group_id="O4" value="1.410" spread="5.5900"/>
                    <measurement group_id="O5" value="0.366" spread="6.1877"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.049" spread="12.2106"/>
                    <measurement group_id="O2" value="0.436" spread="5.3054"/>
                    <measurement group_id="O3" value="-2.595" spread="22.5324"/>
                    <measurement group_id="O4" value="1.053" spread="6.9006"/>
                    <measurement group_id="O5" value="1.122" spread="6.2897"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.048" spread="12.1313"/>
                    <measurement group_id="O2" value="2.974" spread="8.3649"/>
                    <measurement group_id="O3" value="-2.595" spread="24.3852"/>
                    <measurement group_id="O4" value="1.526" spread="6.6688"/>
                    <measurement group_id="O5" value="2.122" spread="6.1733"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="6.375" spread="60.1309"/>
                    <measurement group_id="O2" value="2.821" spread="6.6367"/>
                    <measurement group_id="O3" value="-1.095" spread="25.1317"/>
                    <measurement group_id="O4" value="1.324" spread="7.1065"/>
                    <measurement group_id="O5" value="0.500" spread="4.8569"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.718" spread="23.7940"/>
                    <measurement group_id="O2" value="2.237" spread="6.9182"/>
                    <measurement group_id="O3" value="-1.902" spread="26.1054"/>
                    <measurement group_id="O4" value="2.889" spread="6.2554"/>
                    <measurement group_id="O5" value="0.325" spread="4.3759"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.179" spread="13.4905"/>
                    <measurement group_id="O2" value="2.289" spread="6.9512"/>
                    <measurement group_id="O3" value="-1.805" spread="27.4583"/>
                    <measurement group_id="O4" value="2.229" spread="6.3063"/>
                    <measurement group_id="O5" value="0.175" spread="4.1255"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.385" spread="12.2895"/>
                    <measurement group_id="O2" value="1.949" spread="6.2826"/>
                    <measurement group_id="O3" value="-0.575" spread="28.3177"/>
                    <measurement group_id="O4" value="0.324" spread="6.2654"/>
                    <measurement group_id="O5" value="2.051" spread="4.9997"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.711" spread="7.3113"/>
                    <measurement group_id="O2" value="1.026" spread="5.5140"/>
                    <measurement group_id="O3" value="-1.220" spread="25.5798"/>
                    <measurement group_id="O4" value="1.588" spread="6.6017"/>
                    <measurement group_id="O5" value="1.667" spread="6.0755"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.946" spread="12.1494"/>
                    <measurement group_id="O2" value="1.316" spread="5.5269"/>
                    <measurement group_id="O3" value="0.244" spread="29.2701"/>
                    <measurement group_id="O4" value="-0.647" spread="6.0597"/>
                    <measurement group_id="O5" value="2.462" spread="8.4972"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.838" spread="15.4641"/>
                    <measurement group_id="O2" value="2.553" spread="7.9175"/>
                    <measurement group_id="O3" value="-1.268" spread="28.4280"/>
                    <measurement group_id="O4" value="-0.588" spread="7.7190"/>
                    <measurement group_id="O5" value="1.590" spread="6.9347"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate Aminotransferase Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.158" spread="9.7939"/>
                    <measurement group_id="O2" value="3.459" spread="6.3403"/>
                    <measurement group_id="O3" value="-1.927" spread="28.3182"/>
                    <measurement group_id="O4" value="0.441" spread="6.6796"/>
                    <measurement group_id="O5" value="2.900" spread="6.2339"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.171" spread="5.4447"/>
                    <measurement group_id="O2" value="-2.737" spread="7.0354"/>
                    <measurement group_id="O3" value="-0.535" spread="10.8745"/>
                    <measurement group_id="O4" value="0.171" spread="5.0245"/>
                    <measurement group_id="O5" value="-2.300" spread="6.2684"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.190" spread="5.8736"/>
                    <measurement group_id="O2" value="-2.026" spread="7.6828"/>
                    <measurement group_id="O3" value="-4.116" spread="25.7527"/>
                    <measurement group_id="O4" value="-0.341" spread="5.2517"/>
                    <measurement group_id="O5" value="-1.268" spread="7.8773"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.220" spread="7.2129"/>
                    <measurement group_id="O2" value="-2.641" spread="9.9167"/>
                    <measurement group_id="O3" value="-6.143" spread="35.5504"/>
                    <measurement group_id="O4" value="1.171" spread="17.6265"/>
                    <measurement group_id="O5" value="0.512" spread="16.3968"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.829" spread="5.9745"/>
                    <measurement group_id="O2" value="-4.410" spread="11.6319"/>
                    <measurement group_id="O3" value="11.581" spread="103.8974"/>
                    <measurement group_id="O4" value="-1.795" spread="5.7454"/>
                    <measurement group_id="O5" value="-1.805" spread="9.0698"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.585" spread="5.9033"/>
                    <measurement group_id="O2" value="-2.154" spread="10.7643"/>
                    <measurement group_id="O3" value="-5.762" spread="34.8767"/>
                    <measurement group_id="O4" value="-0.447" spread="8.3785"/>
                    <measurement group_id="O5" value="3.244" spread="21.8229"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.357" spread="9.6445"/>
                    <measurement group_id="O2" value="-1.842" spread="13.4476"/>
                    <measurement group_id="O3" value="-4.357" spread="34.0020"/>
                    <measurement group_id="O4" value="-0.947" spread="8.1868"/>
                    <measurement group_id="O5" value="15.024" spread="77.1617"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.750" spread="9.5051"/>
                    <measurement group_id="O2" value="-2.769" spread="13.0555"/>
                    <measurement group_id="O3" value="-5.452" spread="32.1970"/>
                    <measurement group_id="O4" value="-1.649" spread="5.5137"/>
                    <measurement group_id="O5" value="1.475" spread="22.2722"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.615" spread="12.4173"/>
                    <measurement group_id="O2" value="-2.769" spread="10.9339"/>
                    <measurement group_id="O3" value="-4.122" spread="36.6832"/>
                    <measurement group_id="O4" value="-2.639" spread="9.4360"/>
                    <measurement group_id="O5" value="-2.625" spread="10.3272"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.462" spread="11.5618"/>
                    <measurement group_id="O2" value="-2.132" spread="11.7638"/>
                    <measurement group_id="O3" value="-6.341" spread="36.7434"/>
                    <measurement group_id="O4" value="-2.629" spread="7.6354"/>
                    <measurement group_id="O5" value="-0.200" spread="11.5585"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.359" spread="15.7872"/>
                    <measurement group_id="O2" value="-1.538" spread="13.2463"/>
                    <measurement group_id="O3" value="-7.875" spread="36.9103"/>
                    <measurement group_id="O4" value="-3.676" spread="8.6435"/>
                    <measurement group_id="O5" value="2.795" spread="21.1501"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.026" spread="14.7162"/>
                    <measurement group_id="O2" value="-4.289" spread="11.4559"/>
                    <measurement group_id="O3" value="-8.195" spread="38.6899"/>
                    <measurement group_id="O4" value="-2.735" spread="7.1236"/>
                    <measurement group_id="O5" value="1.410" spread="18.0200"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.568" spread="9.3676"/>
                    <measurement group_id="O2" value="-3.842" spread="13.9275"/>
                    <measurement group_id="O3" value="-9.073" spread="40.5792"/>
                    <measurement group_id="O4" value="-4.088" spread="7.5573"/>
                    <measurement group_id="O5" value="0.925" spread="20.1066"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.081" spread="23.2108"/>
                    <measurement group_id="O2" value="-1.289" spread="21.3730"/>
                    <measurement group_id="O3" value="-7.488" spread="34.4145"/>
                    <measurement group_id="O4" value="-3.824" spread="7.0430"/>
                    <measurement group_id="O5" value="-0.949" spread="11.5643"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma Glutamyl Transferase Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.474" spread="17.6723"/>
                    <measurement group_id="O2" value="-2.184" spread="12.0850"/>
                    <measurement group_id="O3" value="-7.805" spread="35.4924"/>
                    <measurement group_id="O4" value="-2.941" spread="8.8247"/>
                    <measurement group_id="O5" value="2.525" spread="20.6112"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-7.000" spread="16.1509"/>
                    <measurement group_id="O2" value="0.026" spread="19.6118"/>
                    <measurement group_id="O3" value="-1.163" spread="33.1669"/>
                    <measurement group_id="O4" value="-0.585" spread="16.6673"/>
                    <measurement group_id="O5" value="-1.075" spread="18.4341"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.929" spread="18.4858"/>
                    <measurement group_id="O2" value="-0.410" spread="14.9045"/>
                    <measurement group_id="O3" value="-5.930" spread="32.8325"/>
                    <measurement group_id="O4" value="-2.439" spread="19.2146"/>
                    <measurement group_id="O5" value="0.537" spread="19.7270"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.634" spread="25.5693"/>
                    <measurement group_id="O2" value="4.846" spread="21.4372"/>
                    <measurement group_id="O3" value="-6.190" spread="29.5265"/>
                    <measurement group_id="O4" value="0.854" spread="26.6238"/>
                    <measurement group_id="O5" value="-4.293" spread="17.4732"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-3.561" spread="17.3249"/>
                    <measurement group_id="O2" value="0.026" spread="19.0449"/>
                    <measurement group_id="O3" value="0.140" spread="38.8413"/>
                    <measurement group_id="O4" value="3.513" spread="18.6503"/>
                    <measurement group_id="O5" value="1.439" spread="24.0230"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.927" spread="28.3058"/>
                    <measurement group_id="O2" value="4.077" spread="21.0905"/>
                    <measurement group_id="O3" value="2.119" spread="27.5134"/>
                    <measurement group_id="O4" value="3.342" spread="17.0346"/>
                    <measurement group_id="O5" value="1.049" spread="22.9303"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.881" spread="26.0180"/>
                    <measurement group_id="O2" value="15.447" spread="62.0267"/>
                    <measurement group_id="O3" value="-4.381" spread="35.9600"/>
                    <measurement group_id="O4" value="0.474" spread="19.8967"/>
                    <measurement group_id="O5" value="1.488" spread="21.8325"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.200" spread="35.1817"/>
                    <measurement group_id="O2" value="2.154" spread="22.8825"/>
                    <measurement group_id="O3" value="2.500" spread="31.6145"/>
                    <measurement group_id="O4" value="0.676" spread="20.9206"/>
                    <measurement group_id="O5" value="2.025" spread="23.0401"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.462" spread="31.9282"/>
                    <measurement group_id="O2" value="1.333" spread="22.1862"/>
                    <measurement group_id="O3" value="2.878" spread="44.9662"/>
                    <measurement group_id="O4" value="1.944" spread="23.5638"/>
                    <measurement group_id="O5" value="8.550" spread="25.3093"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.436" spread="21.1122"/>
                    <measurement group_id="O2" value="-4.763" spread="21.2138"/>
                    <measurement group_id="O3" value="-2.902" spread="34.3590"/>
                    <measurement group_id="O4" value="8.143" spread="44.0929"/>
                    <measurement group_id="O5" value="1.250" spread="22.0962"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-6.333" spread="23.0587"/>
                    <measurement group_id="O2" value="-6.410" spread="23.8324"/>
                    <measurement group_id="O3" value="-4.525" spread="35.2762"/>
                    <measurement group_id="O4" value="-2.971" spread="27.9171"/>
                    <measurement group_id="O5" value="-1.615" spread="24.8052"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.553" spread="37.3889"/>
                    <measurement group_id="O2" value="-4.658" spread="16.8383"/>
                    <measurement group_id="O3" value="-7.585" spread="35.0442"/>
                    <measurement group_id="O4" value="-6.147" spread="21.6895"/>
                    <measurement group_id="O5" value="5.436" spread="30.0436"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.216" spread="34.5214"/>
                    <measurement group_id="O2" value="-8.289" spread="17.4896"/>
                    <measurement group_id="O3" value="-6.366" spread="36.6898"/>
                    <measurement group_id="O4" value="-10.618" spread="24.4293"/>
                    <measurement group_id="O5" value="0.000" spread="29.3852"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.757" spread="32.2847"/>
                    <measurement group_id="O2" value="-5.316" spread="21.4805"/>
                    <measurement group_id="O3" value="-5.000" spread="34.6259"/>
                    <measurement group_id="O4" value="-5.059" spread="22.2683"/>
                    <measurement group_id="O5" value="1.675" spread="24.9588"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lactate Dehydrogenase Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.447" spread="34.3493"/>
                    <measurement group_id="O2" value="-1.395" spread="23.8061"/>
                    <measurement group_id="O3" value="-4.707" spread="38.6654"/>
                    <measurement group_id="O4" value="-7.441" spread="23.0443"/>
                    <measurement group_id="O5" value="4.500" spread="37.8120"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Biochemistry Parameters During the Study (Albumin)</title>
        <description>Albumin was measured in grams per liter (g/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Biochemistry Parameters During the Study (Albumin)</title>
          <description>Albumin was measured in grams per liter (g/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>g/L</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.000" spread="1.7464"/>
                    <measurement group_id="O2" value="-0.079" spread="2.1357"/>
                    <measurement group_id="O3" value="0.279" spread="1.8038"/>
                    <measurement group_id="O4" value="-0.439" spread="1.8715"/>
                    <measurement group_id="O5" value="-0.350" spread="1.6259"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.500" spread="2.0982"/>
                    <measurement group_id="O2" value="0.051" spread="1.5719"/>
                    <measurement group_id="O3" value="0.419" spread="1.9908"/>
                    <measurement group_id="O4" value="-0.537" spread="2.0988"/>
                    <measurement group_id="O5" value="-0.073" spread="1.8220"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.683" spread="2.4743"/>
                    <measurement group_id="O2" value="0.538" spread="2.1007"/>
                    <measurement group_id="O3" value="0.595" spread="1.9514"/>
                    <measurement group_id="O4" value="-0.171" spread="1.9862"/>
                    <measurement group_id="O5" value="0.220" spread="1.9687"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.634" spread="2.0094"/>
                    <measurement group_id="O2" value="0.154" spread="2.1829"/>
                    <measurement group_id="O3" value="0.581" spread="2.0843"/>
                    <measurement group_id="O4" value="0.077" spread="2.2051"/>
                    <measurement group_id="O5" value="0.195" spread="1.7638"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.073" spread="2.4020"/>
                    <measurement group_id="O2" value="0.538" spread="2.1986"/>
                    <measurement group_id="O3" value="0.857" spread="1.8685"/>
                    <measurement group_id="O4" value="0.211" spread="1.9474"/>
                    <measurement group_id="O5" value="0.415" spread="2.1210"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.833" spread="1.8468"/>
                    <measurement group_id="O2" value="1.132" spread="2.2800"/>
                    <measurement group_id="O3" value="0.881" spread="2.0025"/>
                    <measurement group_id="O4" value="0.316" spread="2.0678"/>
                    <measurement group_id="O5" value="0.683" spread="1.9422"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.175" spread="1.9333"/>
                    <measurement group_id="O2" value="0.487" spread="2.4047"/>
                    <measurement group_id="O3" value="0.976" spread="1.7873"/>
                    <measurement group_id="O4" value="-0.081" spread="2.1000"/>
                    <measurement group_id="O5" value="0.575" spread="1.8659"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.385" spread="1.7262"/>
                    <measurement group_id="O2" value="0.949" spread="2.3164"/>
                    <measurement group_id="O3" value="1.341" spread="1.8790"/>
                    <measurement group_id="O4" value="0.722" spread="2.2502"/>
                    <measurement group_id="O5" value="0.875" spread="2.3004"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.462" spread="2.0881"/>
                    <measurement group_id="O2" value="0.632" spread="2.1362"/>
                    <measurement group_id="O3" value="0.976" spread="1.9169"/>
                    <measurement group_id="O4" value="0.114" spread="1.9819"/>
                    <measurement group_id="O5" value="0.525" spread="2.0999"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.179" spread="1.7452"/>
                    <measurement group_id="O2" value="0.359" spread="1.8706"/>
                    <measurement group_id="O3" value="0.700" spread="1.9897"/>
                    <measurement group_id="O4" value="-0.235" spread="1.6341"/>
                    <measurement group_id="O5" value="0.667" spread="1.9912"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.289" spread="2.6397"/>
                    <measurement group_id="O2" value="0.816" spread="1.7220"/>
                    <measurement group_id="O3" value="0.659" spread="1.6064"/>
                    <measurement group_id="O4" value="-0.029" spread="2.0815"/>
                    <measurement group_id="O5" value="0.436" spread="1.9166"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.108" spread="2.0109"/>
                    <measurement group_id="O2" value="0.763" spread="1.9650"/>
                    <measurement group_id="O3" value="0.805" spread="1.8196"/>
                    <measurement group_id="O4" value="0.000" spread="1.8749"/>
                    <measurement group_id="O5" value="0.400" spread="1.9716"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.297" spread="2.0120"/>
                    <measurement group_id="O2" value="0.132" spread="2.3269"/>
                    <measurement group_id="O3" value="0.659" spread="2.2429"/>
                    <measurement group_id="O4" value="-0.206" spread="1.9661"/>
                    <measurement group_id="O5" value="0.175" spread="2.2858"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.132" spread="2.2800"/>
                    <measurement group_id="O2" value="0.632" spread="2.9903"/>
                    <measurement group_id="O3" value="0.366" spread="3.1682"/>
                    <measurement group_id="O4" value="0.088" spread="2.6671"/>
                    <measurement group_id="O5" value="0.150" spread="2.3044"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Biochemistry Parameters During the Study (Bilirubin, Creatinine, Urate)</title>
        <description>Bilirubin, creatinine, urate were measured in micromols per liter (μmol/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Biochemistry Parameters During the Study (Bilirubin, Creatinine, Urate)</title>
          <description>Bilirubin, creatinine, urate were measured in micromols per liter (μmol/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>μmol/L</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Bilirubin Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.841" spread="2.8968"/>
                    <measurement group_id="O2" value="-1.195" spread="3.1083"/>
                    <measurement group_id="O3" value="-0.465" spread="3.4868"/>
                    <measurement group_id="O4" value="0.471" spread="3.0332"/>
                    <measurement group_id="O5" value="0.385" spread="2.2726"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.762" spread="2.9415"/>
                    <measurement group_id="O2" value="0.492" spread="3.1202"/>
                    <measurement group_id="O3" value="0.516" spread="2.7030"/>
                    <measurement group_id="O4" value="0.978" spread="2.9538"/>
                    <measurement group_id="O5" value="1.395" spread="4.0672"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.290" spread="3.4900"/>
                    <measurement group_id="O2" value="0.789" spread="2.8952"/>
                    <measurement group_id="O3" value="-0.119" spread="3.2318"/>
                    <measurement group_id="O4" value="1.066" spread="3.4454"/>
                    <measurement group_id="O5" value="1.344" spread="3.7625"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.776" spread="3.7242"/>
                    <measurement group_id="O2" value="0.541" spread="3.1822"/>
                    <measurement group_id="O3" value="0.442" spread="3.8005"/>
                    <measurement group_id="O4" value="0.972" spread="3.4557"/>
                    <measurement group_id="O5" value="0.639" spread="2.8243"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.261" spread="2.6113"/>
                    <measurement group_id="O2" value="0.341" spread="3.0050"/>
                    <measurement group_id="O3" value="0.095" spread="2.5793"/>
                    <measurement group_id="O4" value="0.629" spread="3.2367"/>
                    <measurement group_id="O5" value="2.073" spread="4.0034"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.607" spread="3.7361"/>
                    <measurement group_id="O2" value="0.637" spread="3.7786"/>
                    <measurement group_id="O3" value="0.740" spread="3.2505"/>
                    <measurement group_id="O4" value="1.092" spread="3.7662"/>
                    <measurement group_id="O5" value="2.024" spread="3.7217"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="3.3543"/>
                    <measurement group_id="O2" value="0.136" spread="3.4239"/>
                    <measurement group_id="O3" value="1.062" spread="3.8164"/>
                    <measurement group_id="O4" value="1.030" spread="3.8636"/>
                    <measurement group_id="O5" value="1.225" spread="2.9632"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.146" spread="3.2508"/>
                    <measurement group_id="O2" value="0.592" spread="4.4981"/>
                    <measurement group_id="O3" value="0.383" spread="3.1235"/>
                    <measurement group_id="O4" value="1.081" spread="2.8708"/>
                    <measurement group_id="O5" value="1.128" spread="2.8112"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.200" spread="3.6974"/>
                    <measurement group_id="O2" value="-0.068" spread="3.8885"/>
                    <measurement group_id="O3" value="0.105" spread="2.5550"/>
                    <measurement group_id="O4" value="0.449" spread="3.4106"/>
                    <measurement group_id="O5" value="1.595" spread="3.4093"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.233" spread="3.2668"/>
                    <measurement group_id="O2" value="0.262" spread="3.7358"/>
                    <measurement group_id="O3" value="0.655" spread="3.1125"/>
                    <measurement group_id="O4" value="0.994" spread="2.6879"/>
                    <measurement group_id="O5" value="1.669" spread="4.0868"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.942" spread="3.6870"/>
                    <measurement group_id="O2" value="0.776" spread="4.3703"/>
                    <measurement group_id="O3" value="0.078" spread="3.8443"/>
                    <measurement group_id="O4" value="1.012" spread="3.5311"/>
                    <measurement group_id="O5" value="1.095" spread="2.3971"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.600" spread="3.8064"/>
                    <measurement group_id="O2" value="0.679" spread="3.4707"/>
                    <measurement group_id="O3" value="0.415" spread="3.3481"/>
                    <measurement group_id="O4" value="1.065" spread="3.1718"/>
                    <measurement group_id="O5" value="1.433" spread="3.3425"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.019" spread="3.6800"/>
                    <measurement group_id="O2" value="-0.276" spread="3.1827"/>
                    <measurement group_id="O3" value="-0.102" spread="3.1253"/>
                    <measurement group_id="O4" value="0.871" spread="2.8347"/>
                    <measurement group_id="O5" value="1.851" spread="3.7976"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Bilirubin Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.716" spread="4.0370"/>
                    <measurement group_id="O2" value="0.559" spread="3.2460"/>
                    <measurement group_id="O3" value="0.285" spread="3.8393"/>
                    <measurement group_id="O4" value="1.124" spread="3.2882"/>
                    <measurement group_id="O5" value="1.160" spread="3.9493"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.512" spread="6.6788"/>
                    <measurement group_id="O2" value="0.368" spread="7.3757"/>
                    <measurement group_id="O3" value="2.442" spread="7.8628"/>
                    <measurement group_id="O4" value="1.366" spread="8.9044"/>
                    <measurement group_id="O5" value="1.300" spread="6.7300"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.310" spread="11.1300"/>
                    <measurement group_id="O2" value="0.026" spread="6.1194"/>
                    <measurement group_id="O3" value="2.093" spread="8.4426"/>
                    <measurement group_id="O4" value="2.537" spread="6.8304"/>
                    <measurement group_id="O5" value="3.317" spread="6.7470"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.854" spread="10.2508"/>
                    <measurement group_id="O2" value="1.256" spread="7.0812"/>
                    <measurement group_id="O3" value="1.762" spread="8.8229"/>
                    <measurement group_id="O4" value="-0.561" spread="7.3418"/>
                    <measurement group_id="O5" value="2.171" spread="6.9279"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.366" spread="8.3269"/>
                    <measurement group_id="O2" value="1.487" spread="8.3756"/>
                    <measurement group_id="O3" value="3.674" spread="10.1997"/>
                    <measurement group_id="O4" value="1.590" spread="7.9131"/>
                    <measurement group_id="O5" value="3.073" spread="5.7810"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.268" spread="8.0282"/>
                    <measurement group_id="O2" value="0.949" spread="8.6113"/>
                    <measurement group_id="O3" value="6.214" spread="9.5062"/>
                    <measurement group_id="O4" value="1.947" spread="9.1236"/>
                    <measurement group_id="O5" value="2.220" spread="8.2417"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.833" spread="8.4678"/>
                    <measurement group_id="O2" value="1.421" spread="10.7945"/>
                    <measurement group_id="O3" value="3.738" spread="7.7964"/>
                    <measurement group_id="O4" value="0.658" spread="8.7897"/>
                    <measurement group_id="O5" value="3.976" spread="8.2719"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.150" spread="8.3468"/>
                    <measurement group_id="O2" value="1.051" spread="7.7966"/>
                    <measurement group_id="O3" value="4.976" spread="10.5818"/>
                    <measurement group_id="O4" value="2.270" spread="8.5461"/>
                    <measurement group_id="O5" value="4.525" spread="7.4144"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.359" spread="8.1741"/>
                    <measurement group_id="O2" value="0.103" spread="6.8817"/>
                    <measurement group_id="O3" value="3.829" spread="11.4256"/>
                    <measurement group_id="O4" value="1.972" spread="9.3914"/>
                    <measurement group_id="O5" value="4.650" spread="7.2627"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.921" spread="7.0227"/>
                    <measurement group_id="O2" value="1.737" spread="7.4858"/>
                    <measurement group_id="O3" value="4.634" spread="8.9576"/>
                    <measurement group_id="O4" value="1.371" spread="8.3634"/>
                    <measurement group_id="O5" value="4.900" spread="7.2388"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.718" spread="8.8227"/>
                    <measurement group_id="O2" value="2.462" spread="9.1360"/>
                    <measurement group_id="O3" value="2.500" spread="8.9299"/>
                    <measurement group_id="O4" value="4.118" spread="12.0825"/>
                    <measurement group_id="O5" value="4.974" spread="7.7408"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.289" spread="7.5656"/>
                    <measurement group_id="O2" value="1.632" spread="7.1600"/>
                    <measurement group_id="O3" value="1.024" spread="8.8218"/>
                    <measurement group_id="O4" value="1.853" spread="10.8492"/>
                    <measurement group_id="O5" value="3.462" spread="6.8127"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.838" spread="9.5205"/>
                    <measurement group_id="O2" value="2.974" spread="7.3796"/>
                    <measurement group_id="O3" value="4.122" spread="9.7575"/>
                    <measurement group_id="O4" value="0.647" spread="10.7672"/>
                    <measurement group_id="O5" value="3.200" spread="7.0208"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="35"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.543" spread="10.6670"/>
                    <measurement group_id="O2" value="4.250" spread="8.7876"/>
                    <measurement group_id="O3" value="3.659" spread="8.5311"/>
                    <measurement group_id="O4" value="3.364" spread="10.6853"/>
                    <measurement group_id="O5" value="3.925" spread="8.0012"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Creatinine Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="35"/>
                    <count group_id="O2" value="33"/>
                    <count group_id="O3" value="39"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3.000" spread="10.3299"/>
                    <measurement group_id="O2" value="4.667" spread="8.5355"/>
                    <measurement group_id="O3" value="3.923" spread="7.7371"/>
                    <measurement group_id="O4" value="2.879" spread="9.8513"/>
                    <measurement group_id="O5" value="3.256" spread="7.0290"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.220" spread="37.4503"/>
                    <measurement group_id="O2" value="-0.237" spread="43.0100"/>
                    <measurement group_id="O3" value="11.953" spread="60.5652"/>
                    <measurement group_id="O4" value="8.732" spread="39.4088"/>
                    <measurement group_id="O5" value="11.650" spread="61.0924"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="12.405" spread="47.5795"/>
                    <measurement group_id="O2" value="-2.974" spread="44.8826"/>
                    <measurement group_id="O3" value="9.791" spread="61.4009"/>
                    <measurement group_id="O4" value="9.073" spread="39.3430"/>
                    <measurement group_id="O5" value="15.610" spread="49.0693"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10.171" spread="41.5493"/>
                    <measurement group_id="O2" value="0.308" spread="47.3193"/>
                    <measurement group_id="O3" value="13.452" spread="49.1633"/>
                    <measurement group_id="O4" value="5.659" spread="31.2591"/>
                    <measurement group_id="O5" value="-4.293" spread="47.5753"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.415" spread="42.9500"/>
                    <measurement group_id="O2" value="-6.231" spread="40.4198"/>
                    <measurement group_id="O3" value="11.791" spread="64.9910"/>
                    <measurement group_id="O4" value="3.410" spread="33.9518"/>
                    <measurement group_id="O5" value="8.024" spread="44.0043"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10.707" spread="40.2208"/>
                    <measurement group_id="O2" value="6.795" spread="54.4814"/>
                    <measurement group_id="O3" value="13.881" spread="55.3332"/>
                    <measurement group_id="O4" value="7.553" spread="33.4904"/>
                    <measurement group_id="O5" value="2.805" spread="37.6651"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="25.810" spread="44.1965"/>
                    <measurement group_id="O2" value="8.079" spread="50.0062"/>
                    <measurement group_id="O3" value="15.357" spread="59.0311"/>
                    <measurement group_id="O4" value="14.026" spread="40.5173"/>
                    <measurement group_id="O5" value="21.683" spread="41.1670"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="28.950" spread="53.8602"/>
                    <measurement group_id="O2" value="4.692" spread="59.0420"/>
                    <measurement group_id="O3" value="16.048" spread="63.4346"/>
                    <measurement group_id="O4" value="10.622" spread="42.1567"/>
                    <measurement group_id="O5" value="10.600" spread="44.3262"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="17.410" spread="45.0045"/>
                    <measurement group_id="O2" value="9.923" spread="54.9648"/>
                    <measurement group_id="O3" value="3.683" spread="58.6977"/>
                    <measurement group_id="O4" value="6.667" spread="45.2580"/>
                    <measurement group_id="O5" value="6.950" spread="45.8638"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.897" spread="29.4331"/>
                    <measurement group_id="O2" value="9.447" spread="59.8655"/>
                    <measurement group_id="O3" value="18.976" spread="62.4894"/>
                    <measurement group_id="O4" value="-6.371" spread="40.1227"/>
                    <measurement group_id="O5" value="1.250" spread="45.8972"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="17.026" spread="47.8185"/>
                    <measurement group_id="O2" value="2.821" spread="48.9042"/>
                    <measurement group_id="O3" value="5.800" spread="56.2017"/>
                    <measurement group_id="O4" value="3.971" spread="45.1103"/>
                    <measurement group_id="O5" value="17.077" spread="40.3089"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.211" spread="37.5630"/>
                    <measurement group_id="O2" value="-4.868" spread="49.1419"/>
                    <measurement group_id="O3" value="-10.927" spread="59.4228"/>
                    <measurement group_id="O4" value="4.735" spread="42.4309"/>
                    <measurement group_id="O5" value="5.846" spread="49.4259"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="9.730" spread="43.5295"/>
                    <measurement group_id="O2" value="15.605" spread="53.8931"/>
                    <measurement group_id="O3" value="9.976" spread="62.8739"/>
                    <measurement group_id="O4" value="-5.029" spread="41.2630"/>
                    <measurement group_id="O5" value="7.255" spread="46.0833"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="20.541" spread="57.9164"/>
                    <measurement group_id="O2" value="7.605" spread="64.3342"/>
                    <measurement group_id="O3" value="-8.854" spread="67.3523"/>
                    <measurement group_id="O4" value="1.382" spread="47.9558"/>
                    <measurement group_id="O5" value="10.675" spread="50.8963"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Urate Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="8.684" spread="53.6208"/>
                    <measurement group_id="O2" value="3.895" spread="48.5831"/>
                    <measurement group_id="O3" value="-3.220" spread="64.9282"/>
                    <measurement group_id="O4" value="1.853" spread="54.8762"/>
                    <measurement group_id="O5" value="8.050" spread="49.1956"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Biochemistry Parameters During the Study (Calcium, Chloride, Cholesterol, Glucose, Magnesium, Potassium, Sodium)</title>
        <description>Calcium, chloride, cholesterol, glucose, magnesium, potassium, sodium were measured in millimoles per liter (mmol/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Biochemistry Parameters During the Study (Calcium, Chloride, Cholesterol, Glucose, Magnesium, Potassium, Sodium)</title>
          <description>Calcium, chloride, cholesterol, glucose, magnesium, potassium, sodium were measured in millimoles per liter (mmol/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>mmol/L</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Calcium Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.034" spread="0.0810"/>
                    <measurement group_id="O2" value="-0.017" spread="0.0984"/>
                    <measurement group_id="O3" value="-0.008" spread="0.0858"/>
                    <measurement group_id="O4" value="-0.002" spread="0.0990"/>
                    <measurement group_id="O5" value="-0.014" spread="0.0897"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.021" spread="0.0951"/>
                    <measurement group_id="O2" value="0.002" spread="0.0973"/>
                    <measurement group_id="O3" value="0.009" spread="0.1304"/>
                    <measurement group_id="O4" value="-0.024" spread="0.1001"/>
                    <measurement group_id="O5" value="-0.022" spread="0.0938"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.029" spread="0.1079"/>
                    <measurement group_id="O2" value="-0.011" spread="0.1015"/>
                    <measurement group_id="O3" value="-0.021" spread="0.0973"/>
                    <measurement group_id="O4" value="-0.047" spread="0.1147"/>
                    <measurement group_id="O5" value="-0.020" spread="0.0917"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.024" spread="0.0942"/>
                    <measurement group_id="O2" value="-0.006" spread="0.0926"/>
                    <measurement group_id="O3" value="0.008" spread="0.1260"/>
                    <measurement group_id="O4" value="-0.004" spread="0.1105"/>
                    <measurement group_id="O5" value="-0.022" spread="0.0975"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.021" spread="0.1009"/>
                    <measurement group_id="O2" value="-0.025" spread="0.1090"/>
                    <measurement group_id="O3" value="0.021" spread="0.1057"/>
                    <measurement group_id="O4" value="-0.020" spread="0.1088"/>
                    <measurement group_id="O5" value="-0.025" spread="0.0923"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.004" spread="0.0826"/>
                    <measurement group_id="O2" value="-0.006" spread="0.1079"/>
                    <measurement group_id="O3" value="0.023" spread="0.1334"/>
                    <measurement group_id="O4" value="-0.004" spread="0.1027"/>
                    <measurement group_id="O5" value="0.005" spread="0.0888"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.002" spread="0.0931"/>
                    <measurement group_id="O2" value="0.000" spread="0.1013"/>
                    <measurement group_id="O3" value="0.017" spread="0.0999"/>
                    <measurement group_id="O4" value="-0.008" spread="0.0948"/>
                    <measurement group_id="O5" value="-0.018" spread="0.0919"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.011" spread="0.1019"/>
                    <measurement group_id="O2" value="-0.002" spread="0.1028"/>
                    <measurement group_id="O3" value="0.015" spread="0.0845"/>
                    <measurement group_id="O4" value="0.004" spread="0.0896"/>
                    <measurement group_id="O5" value="0.003" spread="0.0974"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.027" spread="0.1117"/>
                    <measurement group_id="O2" value="0.002" spread="0.0877"/>
                    <measurement group_id="O3" value="0.009" spread="0.1068"/>
                    <measurement group_id="O4" value="0.008" spread="0.0909"/>
                    <measurement group_id="O5" value="-0.021" spread="0.1043"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.023" spread="0.1069"/>
                    <measurement group_id="O2" value="0.000" spread="0.0952"/>
                    <measurement group_id="O3" value="0.001" spread="0.1074"/>
                    <measurement group_id="O4" value="-0.017" spread="0.0932"/>
                    <measurement group_id="O5" value="-0.008" spread="0.1024"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="0.1172"/>
                    <measurement group_id="O2" value="0.007" spread="0.0804"/>
                    <measurement group_id="O3" value="-0.005" spread="0.1096"/>
                    <measurement group_id="O4" value="0.001" spread="0.0972"/>
                    <measurement group_id="O5" value="-0.015" spread="0.0936"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.003" spread="0.0905"/>
                    <measurement group_id="O2" value="0.001" spread="0.0807"/>
                    <measurement group_id="O3" value="-0.007" spread="0.1084"/>
                    <measurement group_id="O4" value="-0.019" spread="0.0809"/>
                    <measurement group_id="O5" value="-0.025" spread="0.0947"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.027" spread="0.0920"/>
                    <measurement group_id="O2" value="-0.018" spread="0.0861"/>
                    <measurement group_id="O3" value="-0.008" spread="0.1023"/>
                    <measurement group_id="O4" value="-0.019" spread="0.0839"/>
                    <measurement group_id="O5" value="-0.042" spread="0.0972"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Calcium Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.0881"/>
                    <measurement group_id="O2" value="-0.009" spread="0.1033"/>
                    <measurement group_id="O3" value="-0.014" spread="0.1126"/>
                    <measurement group_id="O4" value="-0.014" spread="0.0912"/>
                    <measurement group_id="O5" value="-0.034" spread="0.0861"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.195" spread="2.1121"/>
                    <measurement group_id="O2" value="-0.105" spread="2.5446"/>
                    <measurement group_id="O3" value="-0.674" spread="4.1388"/>
                    <measurement group_id="O4" value="-0.244" spread="2.5572"/>
                    <measurement group_id="O5" value="-0.125" spread="2.3986"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.214" spread="2.1131"/>
                    <measurement group_id="O2" value="0.308" spread="2.6273"/>
                    <measurement group_id="O3" value="0.093" spread="2.7500"/>
                    <measurement group_id="O4" value="0.415" spread="2.5296"/>
                    <measurement group_id="O5" value="-0.439" spread="2.4192"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.293" spread="1.9525"/>
                    <measurement group_id="O2" value="-0.333" spread="2.2750"/>
                    <measurement group_id="O3" value="0.000" spread="2.4792"/>
                    <measurement group_id="O4" value="0.024" spread="2.6409"/>
                    <measurement group_id="O5" value="0.000" spread="2.6363"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.537" spread="2.1920"/>
                    <measurement group_id="O2" value="0.615" spread="2.4346"/>
                    <measurement group_id="O3" value="0.047" spread="2.6988"/>
                    <measurement group_id="O4" value="0.538" spread="2.3038"/>
                    <measurement group_id="O5" value="0.683" spread="2.4025"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.341" spread="2.2205"/>
                    <measurement group_id="O2" value="-0.282" spread="2.3946"/>
                    <measurement group_id="O3" value="0.548" spread="2.5681"/>
                    <measurement group_id="O4" value="-0.211" spread="2.3499"/>
                    <measurement group_id="O5" value="0.000" spread="2.4393"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.310" spread="1.8934"/>
                    <measurement group_id="O2" value="0.026" spread="2.2837"/>
                    <measurement group_id="O3" value="0.190" spread="2.0864"/>
                    <measurement group_id="O4" value="-0.184" spread="2.2644"/>
                    <measurement group_id="O5" value="-0.268" spread="2.1334"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.325" spread="2.4640"/>
                    <measurement group_id="O2" value="-0.538" spread="2.1502"/>
                    <measurement group_id="O3" value="0.262" spread="2.3484"/>
                    <measurement group_id="O4" value="0.162" spread="2.6616"/>
                    <measurement group_id="O5" value="0.075" spread="2.3685"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.615" spread="2.0081"/>
                    <measurement group_id="O2" value="-0.128" spread="2.5462"/>
                    <measurement group_id="O3" value="-0.390" spread="2.6351"/>
                    <measurement group_id="O4" value="-0.306" spread="2.1885"/>
                    <measurement group_id="O5" value="-0.050" spread="2.5415"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.128" spread="2.3190"/>
                    <measurement group_id="O2" value="0.000" spread="2.6913"/>
                    <measurement group_id="O3" value="0.195" spread="2.3154"/>
                    <measurement group_id="O4" value="0.086" spread="2.5365"/>
                    <measurement group_id="O5" value="0.250" spread="2.5090"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.154" spread="2.2069"/>
                    <measurement group_id="O2" value="0.436" spread="2.3708"/>
                    <measurement group_id="O3" value="0.500" spread="2.2072"/>
                    <measurement group_id="O4" value="0.794" spread="2.3196"/>
                    <measurement group_id="O5" value="0.282" spread="2.0641"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.237" spread="1.9923"/>
                    <measurement group_id="O2" value="0.684" spread="2.4285"/>
                    <measurement group_id="O3" value="0.732" spread="1.9239"/>
                    <measurement group_id="O4" value="0.294" spread="2.5999"/>
                    <measurement group_id="O5" value="0.205" spread="2.4299"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.054" spread="2.5380"/>
                    <measurement group_id="O2" value="0.263" spread="2.6271"/>
                    <measurement group_id="O3" value="0.707" spread="2.4418"/>
                    <measurement group_id="O4" value="0.824" spread="2.4676"/>
                    <measurement group_id="O5" value="0.500" spread="2.4495"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.135" spread="1.9027"/>
                    <measurement group_id="O2" value="0.579" spread="2.6977"/>
                    <measurement group_id="O3" value="0.756" spread="2.1069"/>
                    <measurement group_id="O4" value="0.882" spread="2.8044"/>
                    <measurement group_id="O5" value="0.200" spread="2.5840"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Chloride Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.605" spread="2.0994"/>
                    <measurement group_id="O2" value="0.737" spread="2.8158"/>
                    <measurement group_id="O3" value="1.024" spread="2.4545"/>
                    <measurement group_id="O4" value="0.971" spread="2.5044"/>
                    <measurement group_id="O5" value="0.725" spread="2.7826"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.254" spread="0.4371"/>
                    <measurement group_id="O2" value="0.032" spread="0.4307"/>
                    <measurement group_id="O3" value="0.244" spread="0.5220"/>
                    <measurement group_id="O4" value="0.105" spread="0.4690"/>
                    <measurement group_id="O5" value="0.102" spread="0.3965"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.224" spread="0.4154"/>
                    <measurement group_id="O2" value="0.108" spread="0.5132"/>
                    <measurement group_id="O3" value="0.295" spread="0.5178"/>
                    <measurement group_id="O4" value="0.054" spread="0.5441"/>
                    <measurement group_id="O5" value="0.222" spread="0.6101"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.198" spread="0.6334"/>
                    <measurement group_id="O2" value="-0.023" spread="0.5905"/>
                    <measurement group_id="O3" value="0.210" spread="0.8027"/>
                    <measurement group_id="O4" value="0.093" spread="0.6525"/>
                    <measurement group_id="O5" value="0.151" spread="0.4178"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.190" spread="0.6935"/>
                    <measurement group_id="O2" value="-0.023" spread="0.5770"/>
                    <measurement group_id="O3" value="0.284" spread="0.8012"/>
                    <measurement group_id="O4" value="0.074" spread="0.7920"/>
                    <measurement group_id="O5" value="0.061" spread="0.6268"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.124" spread="0.6719"/>
                    <measurement group_id="O2" value="0.013" spread="0.7473"/>
                    <measurement group_id="O3" value="0.117" spread="0.7616"/>
                    <measurement group_id="O4" value="0.005" spread="0.6045"/>
                    <measurement group_id="O5" value="0.212" spread="0.7491"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.095" spread="0.6811"/>
                    <measurement group_id="O2" value="0.184" spread="0.6378"/>
                    <measurement group_id="O3" value="0.138" spread="0.6814"/>
                    <measurement group_id="O4" value="0.068" spread="0.6014"/>
                    <measurement group_id="O5" value="0.249" spread="0.7075"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.053" spread="0.7609"/>
                    <measurement group_id="O2" value="0.126" spread="0.6889"/>
                    <measurement group_id="O3" value="0.186" spread="0.9669"/>
                    <measurement group_id="O4" value="0.116" spread="0.7101"/>
                    <measurement group_id="O5" value="0.115" spread="0.7718"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.041" spread="0.8729"/>
                    <measurement group_id="O2" value="0.013" spread="0.8673"/>
                    <measurement group_id="O3" value="0.127" spread="1.0682"/>
                    <measurement group_id="O4" value="-0.003" spread="0.6984"/>
                    <measurement group_id="O5" value="0.077" spread="0.5686"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.044" spread="0.9797"/>
                    <measurement group_id="O2" value="-0.037" spread="0.8930"/>
                    <measurement group_id="O3" value="0.076" spread="1.1434"/>
                    <measurement group_id="O4" value="-0.037" spread="0.5801"/>
                    <measurement group_id="O5" value="0.100" spread="0.5923"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.085" spread="0.8540"/>
                    <measurement group_id="O2" value="-0.079" spread="0.8918"/>
                    <measurement group_id="O3" value="0.175" spread="1.0895"/>
                    <measurement group_id="O4" value="-0.050" spread="0.5945"/>
                    <measurement group_id="O5" value="0.256" spread="0.6920"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.005" spread="0.7322"/>
                    <measurement group_id="O2" value="0.024" spread="0.7951"/>
                    <measurement group_id="O3" value="0.117" spread="0.8408"/>
                    <measurement group_id="O4" value="-0.038" spread="0.6597"/>
                    <measurement group_id="O5" value="0.144" spread="0.7950"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.103" spread="0.7541"/>
                    <measurement group_id="O2" value="-0.118" spread="0.9109"/>
                    <measurement group_id="O3" value="0.183" spread="0.8947"/>
                    <measurement group_id="O4" value="-0.135" spread="0.7454"/>
                    <measurement group_id="O5" value="0.110" spread="0.7824"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.170" spread="0.8082"/>
                    <measurement group_id="O2" value="-0.176" spread="1.0874"/>
                    <measurement group_id="O3" value="0.071" spread="0.9341"/>
                    <measurement group_id="O4" value="-0.218" spread="0.9150"/>
                    <measurement group_id="O5" value="-0.000" spread="0.8407"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Cholesterol Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.282" spread="0.7891"/>
                    <measurement group_id="O2" value="-0.279" spread="0.8348"/>
                    <measurement group_id="O3" value="0.012" spread="0.8883"/>
                    <measurement group_id="O4" value="-0.253" spread="0.6653"/>
                    <measurement group_id="O5" value="-0.083" spread="0.5817"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.307" spread="1.3942"/>
                    <measurement group_id="O2" value="0.103" spread="0.7027"/>
                    <measurement group_id="O3" value="0.077" spread="1.1366"/>
                    <measurement group_id="O4" value="0.173" spread="1.0232"/>
                    <measurement group_id="O5" value="-0.060" spread="0.8445"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.062" spread="0.6681"/>
                    <measurement group_id="O2" value="0.013" spread="0.8348"/>
                    <measurement group_id="O3" value="0.221" spread="0.9652"/>
                    <measurement group_id="O4" value="0.129" spread="1.2364"/>
                    <measurement group_id="O5" value="0.190" spread="0.8938"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.298" spread="0.8575"/>
                    <measurement group_id="O2" value="0.015" spread="0.6888"/>
                    <measurement group_id="O3" value="0.248" spread="0.7693"/>
                    <measurement group_id="O4" value="0.249" spread="1.0659"/>
                    <measurement group_id="O5" value="0.134" spread="0.7428"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.112" spread="0.9127"/>
                    <measurement group_id="O2" value="0.308" spread="0.7696"/>
                    <measurement group_id="O3" value="0.258" spread="0.9254"/>
                    <measurement group_id="O4" value="0.344" spread="0.6939"/>
                    <measurement group_id="O5" value="0.256" spread="0.7075"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.110" spread="0.9146"/>
                    <measurement group_id="O2" value="0.005" spread="0.6117"/>
                    <measurement group_id="O3" value="0.188" spread="0.7533"/>
                    <measurement group_id="O4" value="0.111" spread="0.6455"/>
                    <measurement group_id="O5" value="-0.124" spread="0.6636"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.176" spread="0.8363"/>
                    <measurement group_id="O2" value="0.195" spread="0.6316"/>
                    <measurement group_id="O3" value="0.424" spread="1.1521"/>
                    <measurement group_id="O4" value="0.276" spread="0.8280"/>
                    <measurement group_id="O5" value="0.398" spread="0.8332"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.208" spread="1.0560"/>
                    <measurement group_id="O2" value="0.315" spread="1.0225"/>
                    <measurement group_id="O3" value="0.267" spread="1.0132"/>
                    <measurement group_id="O4" value="0.632" spread="0.9741"/>
                    <measurement group_id="O5" value="0.165" spread="1.0366"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.018" spread="1.1856"/>
                    <measurement group_id="O2" value="0.092" spread="0.7747"/>
                    <measurement group_id="O3" value="0.328" spread="0.8554"/>
                    <measurement group_id="O4" value="0.061" spread="1.0462"/>
                    <measurement group_id="O5" value="0.037" spread="0.6295"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.246" spread="1.1812"/>
                    <measurement group_id="O2" value="0.263" spread="0.9371"/>
                    <measurement group_id="O3" value="0.322" spread="1.1372"/>
                    <measurement group_id="O4" value="0.263" spread="1.0053"/>
                    <measurement group_id="O5" value="0.262" spread="0.6412"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.333" spread="1.2671"/>
                    <measurement group_id="O2" value="0.236" spread="0.7013"/>
                    <measurement group_id="O3" value="0.570" spread="1.0301"/>
                    <measurement group_id="O4" value="0.356" spread="1.1021"/>
                    <measurement group_id="O5" value="0.203" spread="0.5945"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.089" spread="0.9061"/>
                    <measurement group_id="O2" value="0.342" spread="0.9406"/>
                    <measurement group_id="O3" value="0.234" spread="1.0379"/>
                    <measurement group_id="O4" value="0.174" spread="1.0175"/>
                    <measurement group_id="O5" value="0.290" spread="0.7789"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.143" spread="1.0885"/>
                    <measurement group_id="O2" value="0.245" spread="1.1081"/>
                    <measurement group_id="O3" value="0.507" spread="1.1257"/>
                    <measurement group_id="O4" value="0.203" spread="0.7420"/>
                    <measurement group_id="O5" value="0.125" spread="0.7016"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.222" spread="1.4919"/>
                    <measurement group_id="O2" value="0.200" spread="1.0950"/>
                    <measurement group_id="O3" value="0.185" spread="0.8688"/>
                    <measurement group_id="O4" value="0.303" spread="1.2760"/>
                    <measurement group_id="O5" value="0.197" spread="0.8966"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glucose Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.013" spread="1.2512"/>
                    <measurement group_id="O2" value="0.045" spread="0.8472"/>
                    <measurement group_id="O3" value="0.141" spread="0.9341"/>
                    <measurement group_id="O4" value="0.276" spread="1.0841"/>
                    <measurement group_id="O5" value="0.100" spread="0.7835"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.010" spread="0.0672"/>
                    <measurement group_id="O2" value="-0.007" spread="0.0676"/>
                    <measurement group_id="O3" value="0.002" spread="0.0694"/>
                    <measurement group_id="O4" value="-0.014" spread="0.0573"/>
                    <measurement group_id="O5" value="-0.015" spread="0.0680"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.0795"/>
                    <measurement group_id="O2" value="0.008" spread="0.0745"/>
                    <measurement group_id="O3" value="-0.011" spread="0.0771"/>
                    <measurement group_id="O4" value="-0.019" spread="0.0624"/>
                    <measurement group_id="O5" value="-0.007" spread="0.0680"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.022" spread="0.0606"/>
                    <measurement group_id="O2" value="0.009" spread="0.0725"/>
                    <measurement group_id="O3" value="-0.012" spread="0.0789"/>
                    <measurement group_id="O4" value="-0.020" spread="0.0712"/>
                    <measurement group_id="O5" value="-0.005" spread="0.0998"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.016" spread="0.0706"/>
                    <measurement group_id="O2" value="-0.008" spread="0.0593"/>
                    <measurement group_id="O3" value="-0.013" spread="0.0819"/>
                    <measurement group_id="O4" value="-0.015" spread="0.0706"/>
                    <measurement group_id="O5" value="-0.006" spread="0.0624"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.010" spread="0.0797"/>
                    <measurement group_id="O2" value="0.008" spread="0.0847"/>
                    <measurement group_id="O3" value="-0.011" spread="0.0733"/>
                    <measurement group_id="O4" value="-0.001" spread="0.0660"/>
                    <measurement group_id="O5" value="0.003" spread="0.0730"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.002" spread="0.0742"/>
                    <measurement group_id="O2" value="0.003" spread="0.0823"/>
                    <measurement group_id="O3" value="-0.021" spread="0.0659"/>
                    <measurement group_id="O4" value="-0.009" spread="0.0629"/>
                    <measurement group_id="O5" value="-0.002" spread="0.0731"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.007" spread="0.0811"/>
                    <measurement group_id="O2" value="-0.012" spread="0.0728"/>
                    <measurement group_id="O3" value="-0.018" spread="0.0659"/>
                    <measurement group_id="O4" value="-0.005" spread="0.0724"/>
                    <measurement group_id="O5" value="-0.009" spread="0.0636"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.005" spread="0.0757"/>
                    <measurement group_id="O2" value="-0.004" spread="0.0572"/>
                    <measurement group_id="O3" value="-0.014" spread="0.0732"/>
                    <measurement group_id="O4" value="-0.009" spread="0.0559"/>
                    <measurement group_id="O5" value="-0.016" spread="0.0664"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.027" spread="0.0713"/>
                    <measurement group_id="O2" value="-0.007" spread="0.0525"/>
                    <measurement group_id="O3" value="-0.018" spread="0.0678"/>
                    <measurement group_id="O4" value="-0.019" spread="0.0719"/>
                    <measurement group_id="O5" value="-0.017" spread="0.0565"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.023" spread="0.0727"/>
                    <measurement group_id="O2" value="-0.016" spread="0.0641"/>
                    <measurement group_id="O3" value="-0.016" spread="0.0603"/>
                    <measurement group_id="O4" value="-0.012" spread="0.0670"/>
                    <measurement group_id="O5" value="-0.013" spread="0.0572"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.015" spread="0.0694"/>
                    <measurement group_id="O2" value="-0.001" spread="0.0596"/>
                    <measurement group_id="O3" value="-0.031" spread="0.0698"/>
                    <measurement group_id="O4" value="-0.004" spread="0.0534"/>
                    <measurement group_id="O5" value="-0.007" spread="0.0563"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.032" spread="0.0681"/>
                    <measurement group_id="O2" value="-0.007" spread="0.0541"/>
                    <measurement group_id="O3" value="-0.014" spread="0.0754"/>
                    <measurement group_id="O4" value="-0.024" spread="0.0636"/>
                    <measurement group_id="O5" value="-0.009" spread="0.0684"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.024" spread="0.0677"/>
                    <measurement group_id="O2" value="-0.000" spread="0.0597"/>
                    <measurement group_id="O3" value="-0.009" spread="0.0685"/>
                    <measurement group_id="O4" value="-0.024" spread="0.0668"/>
                    <measurement group_id="O5" value="-0.016" spread="0.0667"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Magnesium Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.004" spread="0.0633"/>
                    <measurement group_id="O2" value="-0.004" spread="0.0546"/>
                    <measurement group_id="O3" value="-0.014" spread="0.0569"/>
                    <measurement group_id="O4" value="-0.006" spread="0.0616"/>
                    <measurement group_id="O5" value="-0.009" spread="0.0648"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.095" spread="0.2701"/>
                    <measurement group_id="O2" value="0.089" spread="0.3608"/>
                    <measurement group_id="O3" value="0.081" spread="0.4289"/>
                    <measurement group_id="O4" value="-0.017" spread="0.3098"/>
                    <measurement group_id="O5" value="-0.062" spread="0.3216"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.098" spread="0.2975"/>
                    <measurement group_id="O2" value="0.085" spread="0.4095"/>
                    <measurement group_id="O3" value="0.002" spread="0.3327"/>
                    <measurement group_id="O4" value="-0.005" spread="0.3521"/>
                    <measurement group_id="O5" value="0.027" spread="0.3074"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.080" spread="0.2522"/>
                    <measurement group_id="O2" value="0.008" spread="0.3821"/>
                    <measurement group_id="O3" value="0.026" spread="0.2632"/>
                    <measurement group_id="O4" value="0.024" spread="0.4030"/>
                    <measurement group_id="O5" value="-0.063" spread="0.2853"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.056" spread="0.2907"/>
                    <measurement group_id="O2" value="0.069" spread="0.3221"/>
                    <measurement group_id="O3" value="0.014" spread="0.3306"/>
                    <measurement group_id="O4" value="-0.010" spread="0.3135"/>
                    <measurement group_id="O5" value="0.000" spread="0.2520"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.073" spread="0.3217"/>
                    <measurement group_id="O2" value="0.033" spread="0.3398"/>
                    <measurement group_id="O3" value="-0.024" spread="0.3192"/>
                    <measurement group_id="O4" value="-0.082" spread="0.3074"/>
                    <measurement group_id="O5" value="-0.080" spread="0.2977"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.086" spread="0.3258"/>
                    <measurement group_id="O2" value="0.083" spread="0.3112"/>
                    <measurement group_id="O3" value="0.012" spread="0.3651"/>
                    <measurement group_id="O4" value="-0.037" spread="0.3035"/>
                    <measurement group_id="O5" value="-0.020" spread="0.2713"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.092" spread="0.3846"/>
                    <measurement group_id="O2" value="0.031" spread="0.3381"/>
                    <measurement group_id="O3" value="0.055" spread="0.3494"/>
                    <measurement group_id="O4" value="-0.019" spread="0.3627"/>
                    <measurement group_id="O5" value="0.000" spread="0.2774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.095" spread="0.3308"/>
                    <measurement group_id="O2" value="-0.072" spread="0.3052"/>
                    <measurement group_id="O3" value="0.030" spread="0.3844"/>
                    <measurement group_id="O4" value="-0.094" spread="0.3414"/>
                    <measurement group_id="O5" value="-0.062" spread="0.2967"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.077" spread="0.3141"/>
                    <measurement group_id="O2" value="0.105" spread="0.3616"/>
                    <measurement group_id="O3" value="0.063" spread="0.4265"/>
                    <measurement group_id="O4" value="-0.003" spread="0.3312"/>
                    <measurement group_id="O5" value="-0.030" spread="0.3480"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.062" spread="0.3306"/>
                    <measurement group_id="O2" value="0.069" spread="0.3621"/>
                    <measurement group_id="O3" value="0.023" spread="0.4154"/>
                    <measurement group_id="O4" value="0.056" spread="0.2688"/>
                    <measurement group_id="O5" value="0.046" spread="0.3094"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.092" spread="0.3388"/>
                    <measurement group_id="O2" value="0.045" spread="0.3689"/>
                    <measurement group_id="O3" value="0.066" spread="0.4316"/>
                    <measurement group_id="O4" value="0.003" spread="0.3205"/>
                    <measurement group_id="O5" value="0.033" spread="0.3359"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.092" spread="0.3616"/>
                    <measurement group_id="O2" value="0.089" spread="0.3826"/>
                    <measurement group_id="O3" value="0.024" spread="0.3484"/>
                    <measurement group_id="O4" value="-0.003" spread="0.3407"/>
                    <measurement group_id="O5" value="-0.017" spread="0.3456"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.119" spread="0.2933"/>
                    <measurement group_id="O2" value="0.029" spread="0.3571"/>
                    <measurement group_id="O3" value="0.068" spread="0.4344"/>
                    <measurement group_id="O4" value="0.094" spread="0.3084"/>
                    <measurement group_id="O5" value="-0.035" spread="0.3009"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Potassium Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.137" spread="0.3627"/>
                    <measurement group_id="O2" value="-0.053" spread="0.3244"/>
                    <measurement group_id="O3" value="-0.032" spread="0.3274"/>
                    <measurement group_id="O4" value="0.003" spread="0.4123"/>
                    <measurement group_id="O5" value="-0.027" spread="0.3250"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.146" spread="1.5582"/>
                    <measurement group_id="O2" value="-0.184" spread="1.7531"/>
                    <measurement group_id="O3" value="0.000" spread="2.0471"/>
                    <measurement group_id="O4" value="-0.610" spread="2.0722"/>
                    <measurement group_id="O5" value="-0.375" spread="2.1326"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.500" spread="1.6417"/>
                    <measurement group_id="O2" value="-0.513" spread="1.8191"/>
                    <measurement group_id="O3" value="-0.209" spread="1.9341"/>
                    <measurement group_id="O4" value="-0.244" spread="2.0221"/>
                    <measurement group_id="O5" value="-0.341" spread="2.1167"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.732" spread="1.8442"/>
                    <measurement group_id="O2" value="-0.385" spread="1.6482"/>
                    <measurement group_id="O3" value="-0.214" spread="2.3430"/>
                    <measurement group_id="O4" value="-0.707" spread="2.0155"/>
                    <measurement group_id="O5" value="-0.805" spread="1.8196"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.854" spread="2.0070"/>
                    <measurement group_id="O2" value="-0.410" spread="1.3711"/>
                    <measurement group_id="O3" value="-0.860" spread="2.2316"/>
                    <measurement group_id="O4" value="-0.359" spread="1.7394"/>
                    <measurement group_id="O5" value="-0.463" spread="2.2924"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.512" spread="1.8858"/>
                    <measurement group_id="O2" value="-0.513" spread="1.4845"/>
                    <measurement group_id="O3" value="-0.619" spread="2.0357"/>
                    <measurement group_id="O4" value="-0.632" spread="2.1738"/>
                    <measurement group_id="O5" value="-0.854" spread="2.3512"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.738" spread="1.8086"/>
                    <measurement group_id="O2" value="-0.211" spread="1.7423"/>
                    <measurement group_id="O3" value="-0.714" spread="1.7708"/>
                    <measurement group_id="O4" value="-0.842" spread="2.3656"/>
                    <measurement group_id="O5" value="-0.780" spread="1.7250"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.675" spread="1.7155"/>
                    <measurement group_id="O2" value="-0.538" spread="1.4482"/>
                    <measurement group_id="O3" value="-0.857" spread="2.1928"/>
                    <measurement group_id="O4" value="-0.595" spread="2.1661"/>
                    <measurement group_id="O5" value="-0.775" spread="1.9147"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.821" spread="1.7751"/>
                    <measurement group_id="O2" value="-0.487" spread="1.5196"/>
                    <measurement group_id="O3" value="-0.463" spread="2.0137"/>
                    <measurement group_id="O4" value="-0.472" spread="1.8124"/>
                    <measurement group_id="O5" value="-0.725" spread="1.7393"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.462" spread="2.2924"/>
                    <measurement group_id="O2" value="-0.658" spread="1.8494"/>
                    <measurement group_id="O3" value="-0.683" spread="1.8767"/>
                    <measurement group_id="O4" value="-0.457" spread="2.3307"/>
                    <measurement group_id="O5" value="-0.575" spread="2.5609"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-1.077" spread="1.8692"/>
                    <measurement group_id="O2" value="-0.128" spread="1.9219"/>
                    <measurement group_id="O3" value="-0.525" spread="1.8809"/>
                    <measurement group_id="O4" value="-0.441" spread="1.6732"/>
                    <measurement group_id="O5" value="-0.667" spread="1.8257"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.711" spread="2.0122"/>
                    <measurement group_id="O2" value="-0.263" spread="1.8986"/>
                    <measurement group_id="O3" value="-0.512" spread="1.8725"/>
                    <measurement group_id="O4" value="-0.618" spread="1.9850"/>
                    <measurement group_id="O5" value="-0.436" spread="2.2337"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.432" spread="2.1153"/>
                    <measurement group_id="O2" value="-0.474" spread="1.6397"/>
                    <measurement group_id="O3" value="-0.512" spread="2.1578"/>
                    <measurement group_id="O4" value="-0.882" spread="1.9812"/>
                    <measurement group_id="O5" value="-0.950" spread="2.0248"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.486" spread="1.8352"/>
                    <measurement group_id="O2" value="-0.737" spread="2.0492"/>
                    <measurement group_id="O3" value="-0.878" spread="1.9390"/>
                    <measurement group_id="O4" value="-0.647" spread="1.8238"/>
                    <measurement group_id="O5" value="-1.000" spread="2.4179"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sodium Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.237" spread="1.7772"/>
                    <measurement group_id="O2" value="-0.763" spread="1.8074"/>
                    <measurement group_id="O3" value="-0.732" spread="1.8845"/>
                    <measurement group_id="O4" value="-0.706" spread="1.5281"/>
                    <measurement group_id="O5" value="-0.750" spread="2.1334"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Biochemistry Parameters During the Study (Urea Nitrogen)</title>
        <description>Urea nitrogen was measured in millimoles per liter (mmol/L).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Biochemistry Parameters During the Study (Urea Nitrogen)</title>
          <description>Urea nitrogen was measured in millimoles per liter (mmol/L).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>mmol/L</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.093" spread="1.0815"/>
                    <measurement group_id="O2" value="0.126" spread="1.2116"/>
                    <measurement group_id="O3" value="-0.123" spread="1.0989"/>
                    <measurement group_id="O4" value="-0.012" spread="1.0900"/>
                    <measurement group_id="O5" value="0.173" spread="1.5513"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.386" spread="1.8183"/>
                    <measurement group_id="O2" value="-0.208" spread="1.1329"/>
                    <measurement group_id="O3" value="-0.047" spread="1.0359"/>
                    <measurement group_id="O4" value="0.024" spread="1.1762"/>
                    <measurement group_id="O5" value="0.212" spread="1.3064"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.027" spread="1.3217"/>
                    <measurement group_id="O2" value="0.013" spread="1.1307"/>
                    <measurement group_id="O3" value="0.083" spread="1.1244"/>
                    <measurement group_id="O4" value="-0.224" spread="1.1449"/>
                    <measurement group_id="O5" value="0.007" spread="1.2384"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="39"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.007" spread="0.9936"/>
                    <measurement group_id="O2" value="0.023" spread="1.1685"/>
                    <measurement group_id="O3" value="-0.070" spread="1.1143"/>
                    <measurement group_id="O4" value="-0.379" spread="1.2316"/>
                    <measurement group_id="O5" value="0.080" spread="1.1265"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.166" spread="1.2654"/>
                    <measurement group_id="O2" value="-0.244" spread="1.1740"/>
                    <measurement group_id="O3" value="-0.231" spread="1.3357"/>
                    <measurement group_id="O4" value="-0.429" spread="1.1733"/>
                    <measurement group_id="O5" value="-0.151" spread="1.2426"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.133" spread="1.0656"/>
                    <measurement group_id="O2" value="-0.087" spread="0.9793"/>
                    <measurement group_id="O3" value="-0.200" spread="1.3083"/>
                    <measurement group_id="O4" value="-0.218" spread="1.0747"/>
                    <measurement group_id="O5" value="0.012" spread="1.1996"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.207" spread="1.2670"/>
                    <measurement group_id="O2" value="-0.490" spread="1.0901"/>
                    <measurement group_id="O3" value="-0.064" spread="1.2916"/>
                    <measurement group_id="O4" value="-0.357" spread="1.1572"/>
                    <measurement group_id="O5" value="-0.035" spread="1.3202"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="36"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.256" spread="1.1378"/>
                    <measurement group_id="O2" value="-0.523" spread="1.1235"/>
                    <measurement group_id="O3" value="-0.232" spread="1.4951"/>
                    <measurement group_id="O4" value="-0.289" spread="1.1369"/>
                    <measurement group_id="O5" value="-0.138" spread="1.2245"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.267" spread="1.3487"/>
                    <measurement group_id="O2" value="-0.287" spread="1.0992"/>
                    <measurement group_id="O3" value="0.012" spread="1.3020"/>
                    <measurement group_id="O4" value="-0.263" spread="1.1835"/>
                    <measurement group_id="O5" value="-0.082" spread="1.3239"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.097" spread="1.0396"/>
                    <measurement group_id="O2" value="-0.141" spread="1.3098"/>
                    <measurement group_id="O3" value="-0.200" spread="1.1266"/>
                    <measurement group_id="O4" value="-0.326" spread="1.1199"/>
                    <measurement group_id="O5" value="0.082" spread="1.1841"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.203" spread="1.0579"/>
                    <measurement group_id="O2" value="-0.308" spread="1.1757"/>
                    <measurement group_id="O3" value="0.015" spread="1.1094"/>
                    <measurement group_id="O4" value="-0.247" spread="1.1683"/>
                    <measurement group_id="O5" value="-0.018" spread="1.1014"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.214" spread="1.2537"/>
                    <measurement group_id="O2" value="0.192" spread="1.3690"/>
                    <measurement group_id="O3" value="0.068" spread="1.1230"/>
                    <measurement group_id="O4" value="-0.132" spread="1.1834"/>
                    <measurement group_id="O5" value="0.283" spread="1.3435"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.105" spread="1.3389"/>
                    <measurement group_id="O2" value="-0.047" spread="1.3456"/>
                    <measurement group_id="O3" value="-0.054" spread="1.1276"/>
                    <measurement group_id="O4" value="-0.229" spread="1.1979"/>
                    <measurement group_id="O5" value="0.210" spread="1.2264"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.111" spread="1.4431"/>
                    <measurement group_id="O2" value="-0.113" spread="1.1796"/>
                    <measurement group_id="O3" value="-0.222" spread="1.4085"/>
                    <measurement group_id="O4" value="-0.285" spread="1.2611"/>
                    <measurement group_id="O5" value="0.088" spread="1.4580"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Urinalysis Parameters During the Study (Erythrocytes, Leukocytes, Renal Epithelial Casts, Squamous Epithelial Cells, Transitional Epithelial Cells)</title>
        <description>Erythrocytes, leukocytes, renal epithelial casts, squamous epithelial cells, transitional epithelial cells were measured in cells per high power field (cells/HPF).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP. Number of participants reflect those with non-missing urinalysis results during the study.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Urinalysis Parameters During the Study (Erythrocytes, Leukocytes, Renal Epithelial Casts, Squamous Epithelial Cells, Transitional Epithelial Cells)</title>
          <description>Erythrocytes, leukocytes, renal epithelial casts, squamous epithelial cells, transitional epithelial cells were measured in cells per high power field (cells/HPF).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP. Number of participants reflect those with non-missing urinalysis results during the study.</population>
          <units>cells/HPF</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="2"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="5"/>
                <count group_id="O4" value="7"/>
                <count group_id="O5" value="4"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Erythrocytes Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-55.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.750" spread="0.9574"/>
                    <measurement group_id="O3" value="0.333" spread="0.5774"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-54.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-0.500" spread="0.5774"/>
                    <measurement group_id="O3" value="0.250" spread="0.5000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="1.333" spread="2.5166"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="3.333" spread="5.7735"/>
                    <measurement group_id="O3" value="0.000" spread="0.7071"/>
                    <measurement group_id="O4" value="0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="-0.500" spread="0.7071"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.8165"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="1.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-23.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.800" spread="1.3038"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="-0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-55.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.800" spread="1.7889"/>
                    <measurement group_id="O3" value="0.500" spread="1.7321"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="2.500" spread="3.5355"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-30.000" spread="35.3553"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.400" spread="1.1402"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.250" spread="0.5000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="7"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O3" value="0.250" spread="0.5000"/>
                    <measurement group_id="O4" value="-0.143" spread="0.8997"/>
                    <measurement group_id="O5" value="1.000" spread="2.6458"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-5.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.8165"/>
                    <measurement group_id="O3" value="0.400" spread="1.5166"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="2.333" spread="5.7735"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-27.500" spread="38.8909"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.250" spread="0.5000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="2.000" spread="3.4641"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-55.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.250" spread="0.5000"/>
                    <measurement group_id="O4" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O5" value="-1.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O3" value="0.750" spread="1.5000"/>
                    <measurement group_id="O4" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-55.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.400" spread="0.8944"/>
                    <measurement group_id="O4" value="-0.250" spread="1.2583"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Erythrocytes Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-27.500" spread="38.8909"/>
                    <measurement group_id="O2" value="0.167" spread="0.4082"/>
                    <measurement group_id="O3" value="1.750" spread="3.5000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.8165"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="2.750" spread="6.1847"/>
                    <measurement group_id="O3" value="-7.667" spread="13.2791"/>
                    <measurement group_id="O4" value="-0.200" spread="1.0954"/>
                    <measurement group_id="O5" value="0.667" spread="1.1547"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-2.500" spread="2.0817"/>
                    <measurement group_id="O3" value="-3.000" spread="6.6833"/>
                    <measurement group_id="O4" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-4.600" spread="10.2372"/>
                    <measurement group_id="O4" value="0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="2.000" spread="2.8284"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-1.500" spread="3.6968"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="4.000" spread="6.9282"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="1.667" spread="4.7258"/>
                    <measurement group_id="O3" value="13.500" spread="26.3376"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-0.200" spread="1.7889"/>
                    <measurement group_id="O3" value="33.750" spread="67.5000"/>
                    <measurement group_id="O4" value="-0.400" spread="0.8944"/>
                    <measurement group_id="O5" value="0.500" spread="0.7071"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="2.8284"/>
                    <measurement group_id="O2" value="3.000" spread="6.0000"/>
                    <measurement group_id="O3" value="57.800" spread="145.4036"/>
                    <measurement group_id="O4" value="0.667" spread="1.5055"/>
                    <measurement group_id="O5" value="-6.750" spread="14.8633"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="7"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="2.750" spread="4.8563"/>
                    <measurement group_id="O3" value="-6.500" spread="13.0000"/>
                    <measurement group_id="O4" value="2.286" spread="4.8206"/>
                    <measurement group_id="O5" value="0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-2.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-0.750" spread="0.9574"/>
                    <measurement group_id="O3" value="-5.400" spread="12.0748"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="2.333" spread="4.0415"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="3.333" spread="5.7735"/>
                    <measurement group_id="O3" value="-6.500" spread="13.0000"/>
                    <measurement group_id="O4" value="-1.333" spread="1.6330"/>
                    <measurement group_id="O5" value="1.333" spread="2.3094"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.667" spread="2.7325"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="24.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O5" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="-0.500" spread="2.5166"/>
                    <measurement group_id="O3" value="-7.500" spread="15.0000"/>
                    <measurement group_id="O4" value="1.500" spread="3.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.400" spread="0.8944"/>
                    <measurement group_id="O3" value="-1.400" spread="3.1305"/>
                    <measurement group_id="O4" value="-0.500" spread="1.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytes Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="8.000" spread="21.6148"/>
                    <measurement group_id="O3" value="69.500" spread="139.0000"/>
                    <measurement group_id="O4" value="-1.000" spread="1.7321"/>
                    <measurement group_id="O5" value="0.250" spread="0.5000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="7"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.167" spread="0.4082"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O5" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Renal Epithelial Casts Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.250" spread="1.2583"/>
                    <measurement group_id="O3" value="3.000" spread="5.1962"/>
                    <measurement group_id="O4" value="-0.200" spread="0.4472"/>
                    <measurement group_id="O5" value="-0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-8.000" spread="14.6969"/>
                    <measurement group_id="O3" value="-0.250" spread="3.6856"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="-1.667" spread="1.5275"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-1.800" spread="7.1554"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="1.000" spread="1.4142"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.500" spread="1.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-4.333" spread="7.5056"/>
                    <measurement group_id="O3" value="-2.200" spread="5.4955"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-2.750" spread="5.5000"/>
                    <measurement group_id="O4" value="-0.200" spread="0.4472"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.000" spread="1.4142"/>
                    <measurement group_id="O2" value="-2.750" spread="5.5000"/>
                    <measurement group_id="O3" value="-1.400" spread="5.6391"/>
                    <measurement group_id="O4" value="-0.167" spread="0.9832"/>
                    <measurement group_id="O5" value="-0.750" spread="0.9574"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="7"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="1.000" spread="1.4142"/>
                    <measurement group_id="O3" value="1.000" spread="2.0000"/>
                    <measurement group_id="O4" value="-0.286" spread="0.4880"/>
                    <measurement group_id="O5" value="1.333" spread="4.1633"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-3.000" spread="6.0000"/>
                    <measurement group_id="O3" value="0.600" spread="1.3416"/>
                    <measurement group_id="O4" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="-1.667" spread="1.5275"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.500" spread="0.7071"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.500" spread="1.0000"/>
                    <measurement group_id="O4" value="-0.667" spread="0.8165"/>
                    <measurement group_id="O5" value="-0.500" spread="0.7071"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O5" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="-2.750" spread="5.5000"/>
                    <measurement group_id="O3" value="0.750" spread="1.5000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="-0.500" spread="0.7071"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="-1.000" spread="2.2361"/>
                    <measurement group_id="O3" value="0.600" spread="1.3416"/>
                    <measurement group_id="O4" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="-0.500" spread="0.7071"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Squamous Epithelial Cells Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.667" spread="1.6330"/>
                    <measurement group_id="O3" value="1.250" spread="1.8930"/>
                    <measurement group_id="O4" value="0.333" spread="0.5774"/>
                    <measurement group_id="O5" value="-1.000" spread="1.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="1.000" spread="1.7321"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.200" spread="0.4472"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.400" spread="0.8944"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="7"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.167" spread="0.4082"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O5" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.250" spread="0.5000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transitional Epithelial Cells Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Urinalysis Parameters During the Study (Hyaline Casts)</title>
        <description>Hyaline casts was measured in cells per low power field (cells/LPF).</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP. Number of participants reflect those with non-missing urinalysis results during the study.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Urinalysis Parameters During the Study (Hyaline Casts)</title>
          <description>Hyaline casts was measured in cells per low power field (cells/LPF).</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP. Number of participants reflect those with non-missing urinalysis results during the study.</population>
          <units>cells/LPF</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="2"/>
                <count group_id="O2" value="6"/>
                <count group_id="O3" value="5"/>
                <count group_id="O4" value="7"/>
                <count group_id="O5" value="4"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="1.000" spread="1.7321"/>
                    <measurement group_id="O4" value="-0.200" spread="0.4472"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.250" spread="0.5000"/>
                    <measurement group_id="O3" value="1.000" spread="1.1547"/>
                    <measurement group_id="O4" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-0.800" spread="1.0954"/>
                    <measurement group_id="O4" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.333" spread="0.5774"/>
                    <measurement group_id="O3" value="0.250" spread="0.5000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="2"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="5.000" spread="11.1803"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="5"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.500" spread="1.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.500" spread="0.7071"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-0.600" spread="0.8944"/>
                    <measurement group_id="O4" value="1.500" spread="3.6742"/>
                    <measurement group_id="O5" value="-0.750" spread="1.5000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="7"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-0.250" spread="0.5000"/>
                    <measurement group_id="O4" value="0.857" spread="2.2678"/>
                    <measurement group_id="O5" value="0.333" spread="0.5774"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-0.400" spread="0.8944"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="3"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="6"/>
                    <count group_id="O5" value="3"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="1.250" spread="2.5000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="13.333" spread="23.0940"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="1"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O5" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="0.000" spread="0.0000"/>
                    <measurement group_id="O3" value="-0.500" spread="1.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="1"/>
                    <count group_id="O2" value="5"/>
                    <count group_id="O3" value="5"/>
                    <count group_id="O4" value="4"/>
                    <count group_id="O5" value="2"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="NA">Value was not evaluable because only one participant was analyzed.</measurement>
                    <measurement group_id="O2" value="0.400" spread="0.8944"/>
                    <measurement group_id="O3" value="-0.400" spread="0.8944"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="0.000" spread="0.0000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="6"/>
                    <count group_id="O3" value="4"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="4"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.0000"/>
                    <measurement group_id="O2" value="1.167" spread="2.8577"/>
                    <measurement group_id="O3" value="0.000" spread="0.0000"/>
                    <measurement group_id="O4" value="0.000" spread="0.0000"/>
                    <measurement group_id="O5" value="-0.250" spread="0.5000"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Changes From Baseline in Urinalysis Parameters During the Study (pH)</title>
        <description>Urine pH was measured on a pH scale.</description>
        <time_frame>Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48</time_frame>
        <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo (SS)</title>
            <description>Participants received Placebo during the 12 Weeks Double-Blind Period, forming the Safety Set (SS).</description>
          </group>
          <group group_id="O2">
            <title>BKZ 16 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O3">
            <title>BKZ 160 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O4">
            <title>BKZ 160 mg LD (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period, forming the SS.</description>
          </group>
          <group group_id="O5">
            <title>BKZ 320 mg (SS)</title>
            <description>Participants received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) during the 12 Weeks Double-Blind Period followed by the same dose during the 36 Weeks Dose-Blind Period, forming the SS.</description>
          </group>
        </group_list>
        <measure>
          <title>Changes From Baseline in Urinalysis Parameters During the Study (pH)</title>
          <description>Urine pH was measured on a pH scale.</description>
          <population>The SS consisted of all randomized study participants who received at least 1 dose of IMP.</population>
          <units>pH</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="42"/>
                <count group_id="O2" value="39"/>
                <count group_id="O3" value="43"/>
                <count group_id="O4" value="41"/>
                <count group_id="O5" value="41"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Week 1</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.138" spread="0.9198"/>
                    <measurement group_id="O2" value="0.197" spread="0.5875"/>
                    <measurement group_id="O3" value="0.023" spread="0.8014"/>
                    <measurement group_id="O4" value="0.085" spread="0.6011"/>
                    <measurement group_id="O5" value="0.000" spread="0.8321"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 2</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="41"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.155" spread="0.9072"/>
                    <measurement group_id="O2" value="0.154" spread="0.7708"/>
                    <measurement group_id="O3" value="-0.081" spread="0.7149"/>
                    <measurement group_id="O4" value="0.134" spread="0.8293"/>
                    <measurement group_id="O5" value="-0.012" spread="0.7541"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="40"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.195" spread="0.9211"/>
                    <measurement group_id="O2" value="0.026" spread="0.6571"/>
                    <measurement group_id="O3" value="-0.134" spread="0.8368"/>
                    <measurement group_id="O4" value="0.063" spread="0.6620"/>
                    <measurement group_id="O5" value="-0.098" spread="0.6729"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 8</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="41"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.000" spread="0.7826"/>
                    <measurement group_id="O2" value="0.077" spread="0.7393"/>
                    <measurement group_id="O3" value="-0.024" spread="0.8762"/>
                    <measurement group_id="O4" value="0.263" spread="0.7235"/>
                    <measurement group_id="O5" value="0.024" spread="0.7579"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="43"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="41"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.100" spread="1.0203"/>
                    <measurement group_id="O2" value="0.237" spread="0.7600"/>
                    <measurement group_id="O3" value="-0.047" spread="0.6971"/>
                    <measurement group_id="O4" value="0.211" spread="0.6641"/>
                    <measurement group_id="O5" value="0.073" spread="0.8843"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 16</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="42"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="38"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.107" spread="0.8449"/>
                    <measurement group_id="O2" value="0.092" spread="0.7957"/>
                    <measurement group_id="O3" value="-0.122" spread="0.8199"/>
                    <measurement group_id="O4" value="0.118" spread="0.7207"/>
                    <measurement group_id="O5" value="0.088" spread="0.7240"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 20</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="40"/>
                    <count group_id="O2" value="39"/>
                    <count group_id="O3" value="42"/>
                    <count group_id="O4" value="37"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.113" spread="0.7884"/>
                    <measurement group_id="O2" value="0.269" spread="0.8649"/>
                    <measurement group_id="O3" value="-0.012" spread="0.8300"/>
                    <measurement group_id="O4" value="-0.054" spread="0.6539"/>
                    <measurement group_id="O5" value="0.063" spread="0.8929"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 24</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.154" spread="0.9400"/>
                    <measurement group_id="O2" value="-0.013" spread="0.8011"/>
                    <measurement group_id="O3" value="-0.085" spread="0.6605"/>
                    <measurement group_id="O4" value="0.100" spread="0.4820"/>
                    <measurement group_id="O5" value="-0.026" spread="0.6973"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 28</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="35"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.090" spread="0.8419"/>
                    <measurement group_id="O2" value="-0.053" spread="0.6657"/>
                    <measurement group_id="O3" value="-0.122" spread="0.7313"/>
                    <measurement group_id="O4" value="0.086" spread="0.6122"/>
                    <measurement group_id="O5" value="-0.088" spread="0.6783"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 32</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="39"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.218" spread="0.8335"/>
                    <measurement group_id="O2" value="-0.079" spread="0.7491"/>
                    <measurement group_id="O3" value="0.063" spread="0.8784"/>
                    <measurement group_id="O4" value="-0.103" spread="0.6717"/>
                    <measurement group_id="O5" value="-0.269" spread="0.5718"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 36</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.211" spread="0.8353"/>
                    <measurement group_id="O2" value="0.118" spread="0.7300"/>
                    <measurement group_id="O3" value="-0.195" spread="0.8506"/>
                    <measurement group_id="O4" value="-0.118" spread="0.6038"/>
                    <measurement group_id="O5" value="-0.077" spread="0.7569"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 40</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="37"/>
                    <count group_id="O2" value="37"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="34"/>
                    <count group_id="O5" value="39"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.216" spread="0.9394"/>
                    <measurement group_id="O2" value="-0.041" spread="0.6388"/>
                    <measurement group_id="O3" value="-0.188" spread="0.8525"/>
                    <measurement group_id="O4" value="-0.191" spread="0.5643"/>
                    <measurement group_id="O5" value="-0.154" spread="0.7448"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 44</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="36"/>
                    <count group_id="O2" value="38"/>
                    <count group_id="O3" value="41"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="38"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.458" spread="0.7780"/>
                    <measurement group_id="O2" value="-0.171" spread="0.7002"/>
                    <measurement group_id="O3" value="-0.159" spread="0.9044"/>
                    <measurement group_id="O4" value="-0.167" spread="0.6693"/>
                    <measurement group_id="O5" value="-0.171" spread="0.7285"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Week 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="38"/>
                    <count group_id="O2" value="36"/>
                    <count group_id="O3" value="40"/>
                    <count group_id="O4" value="33"/>
                    <count group_id="O5" value="40"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="-0.092" spread="1.0771"/>
                    <measurement group_id="O2" value="-0.014" spread="0.7318"/>
                    <measurement group_id="O3" value="-0.200" spread="0.8533"/>
                    <measurement group_id="O4" value="-0.015" spread="0.7855"/>
                    <measurement group_id="O5" value="-0.100" spread="0.7528"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
    </outcome_list>

    <reported_events>
      <time_frame>Adverse events (AEs) were collected from Baseline until the Safety Follow-Up Visit (up to Week 68)</time_frame>
      <desc>At Week 12, Placebo and BKZ 16 mg subjects were re-randomized to either BKZ 160 mg or BKZ 320 mg. Subjects randomized to BKZ 160 mg or BKZ 320 mg at Baseline were not re-randomized at Week 12 and remained on their treatment. The Safety Set is based on actual treatment, other populations are based on planned treatment. 160mg LD is considered 160mg.</desc>
      <group_list>
        <group group_id="E1">
          <title>Placebo (SS) - up to Wk 12</title>
          <description>This arm consisted of all participants who received Placebo at any time in the study (up to Week 12). Participants formed the Safety Set (SS).</description>
        </group>
        <group group_id="E2">
          <title>BKZ 16 mg (SS) - up to Wk 12</title>
          <description>This arm consisted of all participants who received Bimekizumab (BKZ) 16 milligrams (mg) every 4 weeks (Q4W) at any time in the study (up to Week 12). Participants formed the SS.</description>
        </group>
        <group group_id="E3">
          <title>BKZ 160 mg &amp; 160 mg LD (SS) - up to Wk 68</title>
          <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg at Baseline followed by 160 mg every 4 weeks (Q4W) and Bimekizumab (BKZ) 160 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
        </group>
        <group group_id="E4">
          <title>BKZ 320 mg (SS) - up to Wk 68</title>
          <description>This arm consisted of all participants who received Bimekizumab (BKZ) 320 mg every 4 weeks (Q4W) at any time in the study (up to Week 68). Participants formed the SS.</description>
        </group>
      </group_list>
      <serious_events>
        <default_vocab>MedDRA19.0</default_vocab>
        <default_assessment>Non-systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, all-cause mortality</sub_title>
                <counts group_id="E1" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" subjects_affected="0" subjects_at_risk="126"/>
                <counts group_id="E4" subjects_affected="0" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Total, serious adverse events</sub_title>
                <counts group_id="E1" subjects_affected="1" subjects_at_risk="42"/>
                <counts group_id="E2" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" subjects_affected="8" subjects_at_risk="126"/>
                <counts group_id="E4" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Cardiac disorders</title>
            <event_list>
              <event>
                <sub_title>Atrial fibrillation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Endocrine disorders</title>
            <event_list>
              <event>
                <sub_title>Goitre</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Hepatobiliary disorders</title>
            <event_list>
              <event>
                <sub_title>Drug-induced liver injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Cellulitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Otitis media chronic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Hepatitis E</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Osteoarthritis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Neoplasms benign, malignant and unspecified (incl cysts and polyps)</title>
            <event_list>
              <event>
                <sub_title>Malignant melanoma in situ</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Nervous system disorders</title>
            <event_list>
              <event>
                <sub_title>Carpal tunnel syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </serious_events>
      <other_events>
        <frequency_threshold>5</frequency_threshold>
        <default_vocab>MedDRA19.0</default_vocab>
        <default_assessment>Non-systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, other adverse events</sub_title>
                <counts group_id="E1" subjects_affected="8" subjects_at_risk="42"/>
                <counts group_id="E2" subjects_affected="9" subjects_at_risk="39"/>
                <counts group_id="E3" subjects_affected="40" subjects_at_risk="126"/>
                <counts group_id="E4" subjects_affected="29" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Ear infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="39"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="126"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Respiratory tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="39"/>
                <counts group_id="E3" events="8" subjects_affected="8" subjects_at_risk="126"/>
                <counts group_id="E4" events="3" subjects_affected="2" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Bronchitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="8" subjects_affected="7" subjects_at_risk="126"/>
                <counts group_id="E4" events="3" subjects_affected="3" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Nasopharyngitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="39"/>
                <counts group_id="E3" events="15" subjects_affected="12" subjects_at_risk="126"/>
                <counts group_id="E4" events="11" subjects_affected="11" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Pharyngitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="4" subjects_affected="4" subjects_at_risk="126"/>
                <counts group_id="E4" events="7" subjects_affected="7" subjects_at_risk="80"/>
              </event>
              <event>
                <sub_title>Upper respiratory tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="39"/>
                <counts group_id="E3" events="12" subjects_affected="12" subjects_at_risk="126"/>
                <counts group_id="E4" events="10" subjects_affected="8" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Psoriatic arthropathy</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="42"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="39"/>
                <counts group_id="E3" events="2" subjects_affected="2" subjects_at_risk="126"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Psychiatric disorders</title>
            <event_list>
              <event>
                <sub_title>Insomnia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="39"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="126"/>
                <counts group_id="E4" events="4" subjects_affected="3" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Respiratory, thoracic and mediastinal disorders</title>
            <event_list>
              <event>
                <sub_title>Oropharyngeal pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="42"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="39"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="126"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Vascular disorders</title>
            <event_list>
              <event>
                <sub_title>Hypertension</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="42"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="39"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="126"/>
                <counts group_id="E4" events="2" subjects_affected="2" subjects_at_risk="80"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </other_events>
    </reported_events>

    <certain_agreements>
      <pi_employee>Principal Investigators are NOT employed by the organization sponsoring the study.</pi_employee>
      <restrictive_agreement>The only disclosure restriction on the PI is that the sponsor can review results communications prior to public release and can embargo communications regarding trial results for a period that is more than 60 days but less than or equal to 180 days. The sponsor cannot require changes to the communication and cannot extend the embargo.</restrictive_agreement>
    </certain_agreements>
    <limitations_and_caveats>Biomarker assays were not rigorously validated, thus it was not possible to use results for PD as a secondary objective. The results were interpreted with caution for exploratory purpose, and thus are not shared in this report.</limitations_and_caveats>
    <point_of_contact>
      <name_or_title>UCB</name_or_title>
      <organization>Cares</organization>
      <phone>+1844 599 ext 2273</phone>
      <email>UCBCares@ucb.com</email>
    </point_of_contact>
  </clinical_results>
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT02969525
org study id: PA0008
secondary id: 2016-001103-23
nct id: NCT02969525
lead sponsor: 
has dmc: Yes
This is a study to evaluate the dose response based on the efficacy, safety and tolerability
      of bimekizumab in subjects with active psoriatic arthritis.
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Treatment
masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
measure: ACR50 (American College of Rheumatology 50% Improvement) Response at Week 12
time frame: Week 12
description: The ACR50 response rate was based on 50% improvement relative to Baseline in the following measures:
Tender Joint Count (TJC) based on 78 joints
Swollen Joint Count (SJC) based on 76 joints
3 of the 5 remaining core set measures:
Disease activity as assessed by Patient's Global Assessment of Disease Activity (PGADA)
Disease activity as assessed by Physician's Global Assessment of Disease Activity (PhGADA)
Pain as assessed by Patient's Assessment of Arthritis Pain (PtAAP)
Physical function as assessed by Health Assessment Questionnaire - Disability Index (HAQ-DI)
Acute phase response as assessed by high sensitivity C-reactive protein (hs CRP).
measure: ACR20 (American College of Rheumatology 20% Improvement) Response at Week 12
time frame: Week 12
description: The ACR20 response rate was based on 20% improvement relative to Baseline in the following measures:
TJC based on 78 joints
SJC based on 76 joints
3 of the 5 remaining core set measures:
Disease activity as assessed by PGADA
Disease activity as assessed by PhGADA
Pain as assessed by PtAAP
Physical function as assessed by HAQ-DI
Acute phase response as assessed by hs CRP
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.
measure: ACR70 (American College of Rheumatology 70% Improvement) Response at Week 12
time frame: Week 12
description: The ACR70 response rate was based on 70% improvement relative to Baseline in the following measures:
TJC based on 78 joints
SJC based on 76 joints
3 of the 5 remaining core set measures:
Disease activity as assessed by PGADA
Disease activity as assessed by PhGADA
Pain as assessed by PtAAP
Physical function as assessed by HAQ-DI
Acute phase response as assessed by hs CRP
Note: Nonresponder imputation was used to account for missing data in the primary analysis, the study participants with a missing ACR score at Week 12 or who discontinued IMP prior to the Week 12 Visit were considered nonresponders for the primary analysis.
measure: PASI90 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1
time frame: Week 12
description: The PASI90 response assessments are based on at least 90% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.
measure: PASI75 (Psoriasis Area Severity Index) Response at Week 12 in the Subgroup of Subjects With Psoriasis Involving at Least 3 % Body Surface Area (BSA) at Baseline/Day 1
time frame: Week 12
description: The PASI75 response assessments are based on at least 75% improvement in the PASI score from Baseline. This is a scoring system that averages the redness, thickness, and scaliness of the psoriatic lesions (on a 0-4 scale), and weights the resulting score by the area of skin involved. Body divided into 4 areas: head, arms, trunk to groin, and legs to top of buttocks. Assignment of an average score for the redness, thickness, and scaling for each of the 4 body areas with a score of 0 (clear) to 4 (very marked).
Determining the percentage of skin covered with PSO for each of the body areas and converting to a 0 to 6 scale. Final PASI= average redness, thickness, and scaliness of the psoriatic skin lesions, multiplied by the involved psoriasis area score of the respective section, and weighted by the percentage of the person's affected skin for the respective section. The minimum possible PASI score is 0= no disease, the maximum score is 72= maximal disease.
measure: Percentage of Participants With at Least One Adverse Event (AE) During the Study
time frame: From Screening Period until the Safety Follow-Up Visit (up to Week 72)
description: An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.
measure: Percentage of Participants With at Least One Serious Adverse Event (SAE) During the Study
time frame: From Screening Period until the Safety Follow-Up Visit (up to Week 72)
description: A Serious Adverse Event (SAE) is any untoward medical occurrence that at any dose:
Results in death
Is life-threatening
Requires in patient hospitalization or prolongation of existing hospitalization
Is a congenital anomaly or birth defect
Is an infection that requires treatment parenteral antibiotics
Other important medical events which based on medical or scientific judgement may jeopardize the patients, or may require medical or surgical intervention to prevent any of the above.
measure: Percentage of Participants Who Withdrew Due to an Adverse Event (AE) During the Study
time frame: From Screening Period until the Safety Follow-Up Visit (up to Week 72)
description: An adverse event (AE) was any untoward medical occurrence in a patient or clinical study participant, temporally associated with the use of investigational medicinal product (IMP), whether or not considered related to the IMP. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of IMP.
measure: Changes From Baseline in Vital Signs During the Study (Diastolic Blood Pressure, Systolic Blood Pressure)
time frame: Baseline, 30 min and 1 hour post dose, Week 1, Week 2, pre- and post dose for the following Weeks: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 and 44 and Week 48
description: Diastolic and systolic blood pressure were measured in millimeters of mercury (mmHg).
measure: Changes From Baseline in Vital Signs During the Study (Pulse Rate)
time frame: Baseline, 30 min and 1 hour post dose, Week 1, Week 2, pre- and post dose for the following Weeks: 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 and 44 and Week 48
description: Pulse rate was measured in beats per minute (beats/min).
measure: Changes From Baseline in Body Weight During the Study
time frame: Baseline, Week 12, Week 24, Week 36 and Week 48
description: Body weight was measured in kilograms.
measure: Changes From Baseline in Electrocardiogram (ECG) Intervals During the Study (QTcB, QTcF, PR, QRS, QT, RR)
time frame: Baseline, Week 12 and Week 48
description: Electrocardiogram (ECG) intervals (QTcB= QT interval corrected for heart rate (Bazett's formula); QTcF= QT interval corrected for heart rate (Fridericia's formula)) were measured in milliseconds.
measure: Changes From Baseline in Hematology Parameters During the Study (Basophils, Eosinophils, Leukocytes, Lymphocytes, Monocytes, Neutrophils)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Basophils, eosinophils, leukocytes, lymphocytes, monocytes, neutrophils were measured in number of white blood cells per liter (10^9/L).
measure: Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB) Concentration, Hemoglobin)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Erythrocytes mean corpuscular hemoglobin (HGB) concentration and hemoglobin were measured in grams per liter (g/L).
measure: Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Hemoglobin (HGB))
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Erythrocytes mean corpuscular hemoglobin (HGB) was measured in picograms (pg).
measure: Changes From Baseline in Hematology Parameters During the Study (Erythrocytes Mean Corpuscular Volume)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Erythrocytes mean corpuscular volume was measured in femtolitres (fL).
measure: Changes From Baseline in Hematology Parameters During the Study (Erythrocytes)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Erythrocytes was measured in number of red blood cells per liter (10^12/L).
measure: Changes From Baseline in Hematology Parameters During the Study (Hematocrit)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Hematocrit was measured in volume percentage (%) of red blood cells in blood.
measure: Changes From Baseline in Hematology Parameters During the Study (Platelets)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Platelets was measured in number of platelets per liter (10^9/L).
measure: Changes From Baseline in Biochemistry Parameters During the Study (Alanine Aminotransferase, Alkaline Phosphatase, Aspartate Aminotransferase, Gamma Glutamyl Transferase, Lactate Dehydrogenase)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, gamma glutamyl transferase, lactate dehydrogenase were measured in units per liter (U/L).
measure: Changes From Baseline in Biochemistry Parameters During the Study (Albumin)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Albumin was measured in grams per liter (g/L).
measure: Changes From Baseline in Biochemistry Parameters During the Study (Bilirubin, Creatinine, Urate)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Bilirubin, creatinine, urate were measured in micromols per liter (μmol/L).
measure: Changes From Baseline in Biochemistry Parameters During the Study (Calcium, Chloride, Cholesterol, Glucose, Magnesium, Potassium, Sodium)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Calcium, chloride, cholesterol, glucose, magnesium, potassium, sodium were measured in millimoles per liter (mmol/L).
measure: Changes From Baseline in Biochemistry Parameters During the Study (Urea Nitrogen)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Urea nitrogen was measured in millimoles per liter (mmol/L).
measure: Changes From Baseline in Urinalysis Parameters During the Study (Erythrocytes, Leukocytes, Renal Epithelial Casts, Squamous Epithelial Cells, Transitional Epithelial Cells)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Erythrocytes, leukocytes, renal epithelial casts, squamous epithelial cells, transitional epithelial cells were measured in cells per high power field (cells/HPF).
measure: Changes From Baseline in Urinalysis Parameters During the Study (Hyaline Casts)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Hyaline casts was measured in cells per low power field (cells/LPF).
measure: Changes From Baseline in Urinalysis Parameters During the Study (pH)
time frame: Baseline, Week 1, Week 2, Week 4, Week 8, Week 12, Week 16, Week 20, Week 24, Week 28, Week 32, Week 36, Week 40, Week 44 and Week 48
description: Urine pH was measured on a pH scale.
arm group label: Placebo
arm group type: Placebo Comparator
description: Subjects will receive for 12 Weeks Placebo and will then be re-randomized to Bimekizumab dosage regimen 2 or Bimekizumab dosage regimen 3 for 36 Weeks.
arm group label: Bimekizumab dosage regimen 1
arm group type: Experimental
description: Subjects will receive for 12 Weeks Bimekizumab dosage regimen 1 and will then be re-randomized to Bimekizumab dosage regimen 2 or Bimekizumab dosage regimen 3 for 36 Weeks.
arm group label: Bimekizumab dosage regimen 2
arm group type: Experimental
description: Subjects will receive for 48 Weeks Bimekizumab dosage regimen 2.
arm group label: Bimekizumab dosage regimen 3
arm group type: Experimental
description: Subjects will receive for 48 Weeks Bimekizumab dosage regimen 3.
arm group label: Bimekizumab dosage regimen 4
arm group type: Experimental
description: Subjects will receive for 12 Weeks Bimekizumab dosage regimen 4 and will then be re-randomized to Bimekizumab dosage regimen 2 for 36 Weeks.
intervention type: Other
intervention name: Placebo
arm group label: Placebo
intervention type: Drug
intervention name: Bimekizumab
description: Bimekizumab in different dosage regimens.
arm group label: Bimekizumab dosage regimen 1
arm group label: Bimekizumab dosage regimen 2
arm group label: Bimekizumab dosage regimen 3
arm group label: Bimekizumab dosage regimen 4
other name: UCB4940
criteria: 
gender: All
minimum age: 18 Years
maximum age: N/A
healthy volunteers: No
last name: UCB Cares
role: Study Director
affiliation: +1 844 599 2273(UCB)
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
facility: 
country: Czechia
country: Germany
country: Hungary
country: Poland
country: Russian Federation
country: United States
country: Czech Republic
citation: Mease PJ, Asahina A, Gladman DD, Tanaka Y, Tillett W, Ink B, Assudani D, de la Loge C, Coarse J, Eells J, Gossec L. Effect of bimekizumab on symptoms and impact of disease in patients with psoriatic arthritis over 3 years: results from BE ACTIVE. Rheumatology (Oxford). 2023 Feb 1;62(2):617-628. doi: 10.1093/rheumatology/keac353.
PMID: 35789257
responsible party type: Sponsor
mesh term: Arthritis
mesh term: Arthritis, Psoriatic
provided document: 
provided document: 
participant flow: 
baseline: 
outcome list: 
reported events: 
certain agreements: 
limitations and caveats: Biomarker assays were not rigorously validated, thus it was not possible to use results for PD as a secondary objective. The results were interpreted with caution for exploratory purpose, and thus are not shared in this report.
point of contact: 