<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT02206347</url>
  </required_header>
  <id_info>
    <org_study_id>201209056RIC</org_study_id>
    <nct_id>NCT02206347</nct_id>
  </id_info>
  <brief_title>The Effect of Prioritization of Attentional Allocation on Postural-suprapostural Tasking</brief_title>
  <official_title>The Effect of Prioritization of Attentional Allocation on Postural-suprapostural Tasking</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>National Taiwan University Hospital</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>National Taiwan University Hospital</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      Postural-suprapostural task is defined as postural control takes place while at least one&#xD;
      other concurrent task is being performed, and appropriate locus of attentional allocation is&#xD;
      considered a critical factor for successful postural-suprapostural execution. Recent studies&#xD;
      have indicated that the behavior performance of postural-suprapostural task would be affected&#xD;
      by the prioritization of attentional allocation (postural-first vs. suprapostural-first);&#xD;
      however, the inference of the appropriateness of attention prioritization is primarily&#xD;
      limited to behavior observations and lacks direct neural evidences. How the effect of&#xD;
      attentional priority between postural and suprapostural tasks on postural-suprapostural&#xD;
      performance and its underlying cortical mechanism is rarely understood. By adopting&#xD;
      postural-first and suprapostural-first strategies for postural-suprapostural task, the&#xD;
      purpose of this 2-year research project is to 1) investigate the differences in performance&#xD;
      quality and intrinsic neural mechanisms effect of a postural-suprapostural task for healthy&#xD;
      adults with the analysis of event-related potential (ERP) and non-linear dynamics of behavior&#xD;
      measures; 2) investigate brain plastic changes and the appropriateness of strategy use. In&#xD;
      the first year, the attention prioritization effect on reciprocity of a&#xD;
      postural-suprapostural task will be characterized by integrating the results of behavior&#xD;
      performance and ERP causal connectivity with a special focus on validation of prevailing&#xD;
      theoretical models. In the second year, the difference of task fluent for learning a&#xD;
      postural-suprapostural task with postural-first/suprapostural-first strategy will be studied&#xD;
      through the spatial and time variations in alpha rhythm after principle component analysis.&#xD;
      The present project is expected to have significant contributions not only to gain a better&#xD;
      insight to neural correlates of concurrent postural and motor suprapostural tasks, but to&#xD;
      optimize treatment strategy for patients with balance or multi-tasking disturbances.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Recruiting</last_known_status>
  <start_date>March 2013</start_date>
  <completion_date type="Anticipated">July 2015</completion_date>
  <primary_completion_date type="Anticipated">July 2015</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>N/A</allocation>
    <intervention_model>Single Group Assignment</intervention_model>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>precision-grip force error</measure>
    <time_frame>up to 2 years</time_frame>
    <description>The precision-grip force error is used as the performance of suprapostural task</description>
  </primary_outcome>
  <primary_outcome>
    <measure>balance</measure>
    <time_frame>up to 2 years</time_frame>
    <description>The balance measure is used as the postural performance.</description>
  </primary_outcome>
  <number_of_arms>1</number_of_arms>
  <enrollment type="Anticipated">60</enrollment>
  <condition>Attention on Posture</condition>
  <condition>Attention on Supraposture</condition>
  <arm_group>
    <arm_group_label>attention focus</arm_group_label>
    <arm_group_type>Other</arm_group_type>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>attention focus</intervention_name>
    <arm_group_label>attention focus</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  healthy adults without neuromuscular / cardiovascular disease&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  pregnant women&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>20 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
  </eligibility>
  <location>
    <facility>
      <name>National Taiwan University</name>
      <address>
        <city>Taipei</city>
        <zip>100</zip>
        <country>Taiwan</country>
      </address>
    </facility>
    <status>Recruiting</status>
    <contact>
      <last_name>Cheng-Ya Huang</last_name>
      <phone>886-2-33668131</phone>
      <email>rcyhuang@ntu.edu.tw</email>
    </contact>
  </location>
  <location_countries>
    <country>Taiwan</country>
  </location_countries>
  <verification_date>July 2014</verification_date>
  <study_first_submitted>July 28, 2014</study_first_submitted>
  <study_first_submitted_qc>July 31, 2014</study_first_submitted_qc>
  <study_first_posted type="Estimate">August 1, 2014</study_first_posted>
  <last_update_submitted>July 31, 2014</last_update_submitted>
  <last_update_submitted_qc>July 31, 2014</last_update_submitted_qc>
  <last_update_posted type="Estimate">August 1, 2014</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <pending_results>
    <submitted>August 25, 2015</submitted>
    <returned>September 29, 2015</returned>
  </pending_results>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT02206347
org study id: 201209056RIC
nct id: NCT02206347
lead sponsor: 
has dmc: No
Postural-suprapostural task is defined as postural control takes place while at least one
      other concurrent task is being performed, and appropriate locus of attentional allocation is
      considered a critical factor for successful postural-suprapostural execution. Recent studies
      have indicated that the behavior performance of postural-suprapostural task would be affected
      by the prioritization of attentional allocation (postural-first vs. suprapostural-first);
      however, the inference of the appropriateness of attention prioritization is primarily
      limited to behavior observations and lacks direct neural evidences. How the effect of
      attentional priority between postural and suprapostural tasks on postural-suprapostural
      performance and its underlying cortical mechanism is rarely understood. By adopting
      postural-first and suprapostural-first strategies for postural-suprapostural task, the
      purpose of this 2-year research project is to 1) investigate the differences in performance
      quality and intrinsic neural mechanisms effect of a postural-suprapostural task for healthy
      adults with the analysis of event-related potential (ERP) and non-linear dynamics of behavior
      measures; 2) investigate brain plastic changes and the appropriateness of strategy use. In
      the first year, the attention prioritization effect on reciprocity of a
      postural-suprapostural task will be characterized by integrating the results of behavior
      performance and ERP causal connectivity with a special focus on validation of prevailing
      theoretical models. In the second year, the difference of task fluent for learning a
      postural-suprapostural task with postural-first/suprapostural-first strategy will be studied
      through the spatial and time variations in alpha rhythm after principle component analysis.
      The present project is expected to have significant contributions not only to gain a better
      insight to neural correlates of concurrent postural and motor suprapostural tasks, but to
      optimize treatment strategy for patients with balance or multi-tasking disturbances.
allocation: N/A
intervention model: Single Group Assignment
masking: None (Open Label)
measure: precision-grip force error
time frame: up to 2 years
description: The precision-grip force error is used as the performance of suprapostural task
measure: balance
time frame: up to 2 years
description: The balance measure is used as the postural performance.
arm group label: attention focus
arm group type: Other
intervention type: Behavioral
intervention name: attention focus
arm group label: attention focus
criteria: 
gender: All
minimum age: 20 Years
maximum age: N/A
healthy volunteers: Accepts Healthy Volunteers
facility: 
status: Recruiting
contact: 
country: Taiwan
responsible party type: Sponsor
submitted: August 25, 2015
returned: September 29, 2015