<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT02247882</url>
  </required_header>
  <id_info>
    <org_study_id>RCTOA14</org_study_id>
    <secondary_id>1406</secondary_id>
    <nct_id>NCT02247882</nct_id>
  </id_info>
  <brief_title>Effectiveness of Aquatic Physical Therapy for Knee Osteoarthritis Patients</brief_title>
  <acronym>RCT-OA</acronym>
  <official_title>Effectiveness of Health Education Compared to Aquatic Physical Therapy for Patients With Knee Osteoarthritis: a Randomized Clinical Trial</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Universidade Estadual de Londrina</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
    <collaborator>
      <agency>Ministry of Health, Brazil</agency>
      <agency_class>Other</agency_class>
    </collaborator>
    <collaborator>
      <agency>Fundação Araucária</agency>
      <agency_class>Other</agency_class>
    </collaborator>
  </sponsors>
  <source>Universidade Estadual de Londrina</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      The purpose of this study is to determine whether education or aquatic physical therapy are&#xD;
      effective in the treatment of osteoarthritis in Knee due to intensity of pain, function&#xD;
      capacity, quality of life and kinetic.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Sixty patients will be recruited from clinics and through printed newspaper. Physicians who&#xD;
      routinely evaluate patients with this diagnosis will be informed of the study, and the same&#xD;
      will be announced by television call.&#xD;
&#xD;
      After passing a medical examination confirming the clinical diagnosis of knee osteoarthritis&#xD;
      by American College of Rheumatology and other criteria, the elect will be informed of the&#xD;
      objectives of the study and invited to participate.&#xD;
&#xD;
      After evaluation of the records of referrals of knee OA, patients receive phone calls, will&#xD;
      be informed of the research objectives, questioned regarding the inclusion and exclusion&#xD;
      criteria of the study and invited to participate in the study.&#xD;
&#xD;
      Upon study entry, personal information (name, age, gender, address and telephone) will be&#xD;
      confirmed by a secretary, who will give the registration number of the patient. Personal&#xD;
      information, as well as their radiographs, will be kept in personal form, with number of&#xD;
      study enrollment.&#xD;
&#xD;
      Before and after implementation of treatment protocols, as well as after three months, all&#xD;
      patients will be assessed by an independent examiner, ie, that have no knowledge about the&#xD;
      intervention with respect to different variables. The independent examiner will have been&#xD;
      previously trained for this role to become fit to do so.&#xD;
&#xD;
      Individuals will be assessed using the rubric for the outcomes of pain intensity using a&#xD;
      Visual Analogue Scale (VAS); functional capacity of the Western Ontario and McMaster&#xD;
      Universities Index (WOMAC); balance the Activities-specific Balance Confidence (ABC) and by&#xD;
      static posturography and reaction forces to the ground by static force platform. Body weight&#xD;
      will be checked by portable scale; height, and waist circumference with tape measure to&#xD;
      calculate BMI.&#xD;
&#xD;
      After evaluation, patients will be divided by the numbers generated by the computer through&#xD;
      the site (www.random.org) in both treatment groups with 30 patients. After the generation of&#xD;
      numbers, they will be transformed into a card with the assigned treatment (1- Patient&#xD;
      Education; 2 Aquatic Physiotherapy) and then placed in sealed, opaque, sequentially numbered&#xD;
      envelopes. Thus, it prevented the evaluator and the therapist choose the group to which the&#xD;
      patient is assigned. Procedures for randomization and allocation, as well as assessments and&#xD;
      interventions will be blinded.&#xD;
&#xD;
      The educational program will comprise a multidisciplinary team: doctor, pharmacist, nurse,&#xD;
      nutritionist, psychologist, physiotherapist and physical educator. Classes will be weekly in&#xD;
      groups for eight weeks, lasting two hours, to be held in the Parlor of Our Lady of Grace&#xD;
      Church, belonging to the scope of the Health Unit Vila Brazil.&#xD;
&#xD;
      The program will include education, following the suggestions of Coleman et al. the following&#xD;
      items: guidelines about the disease and its complications, strategies for pain management&#xD;
      (pharmacological and cognitive), physical exercise, nutrition and weight control, medication&#xD;
      (type, interactions, current trends, side effects), balance, proprioception , fall&#xD;
      prevention, coping with chronic pain. Following, practical activities on the themes will be&#xD;
      addressed.&#xD;
&#xD;
      To enhance the information at the end, patients will receive printed material with the&#xD;
      guidelines given by the professional. Still, the first and last day of the education program,&#xD;
      patients will respond a questionnaire addressing their knowledge about the disease developed&#xD;
      by the researchers.&#xD;
&#xD;
      Supervised aquatic exercise will run individually, twice a week, lasting 60 minutes, for&#xD;
      eight weeks, totaling 16 sessions at the Center for Aquatic Physical Therapy Professor Paulo&#xD;
      Armindo Seibert, Universidade Estadual de Londrina. The water temperature will be maintained&#xD;
      at approximately 32 degrees, with a depth of 1.20m. The exercise protocol will consist of:&#xD;
      five minutes of heating with walking and patellar mobilization; ten minutes stretching the&#xD;
      muscles of the lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps&#xD;
      and hamstrings); ten minutes isometric and dynamic exercises with elastic (quadriceps,&#xD;
      gluteus, adductors and abductors of hip sural triceps and hamstrings); twenty minutes away&#xD;
      from aerobic exercise (stationary running deep water running); ten minutes in functional&#xD;
      training step and proprioceptive exercises; and five minutes of cooling with stretching of&#xD;
      muscles of lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps and&#xD;
      hamstrings).&#xD;
&#xD;
      Both groups will receive guidance home exercises two to three times a week, and reinforced by&#xD;
      familiar previously illustrated booklets, which include the same goals of aquatic exercises:&#xD;
      heating, self stretching of the lower limb muscles, isometric and dynamic exercises of the&#xD;
      lower limbs , proprioceptive and functional exercises, aerobic exercises is relaxation.&#xD;
&#xD;
      Three months after the end of intervention protocols, ie, at the end of follow-up, patients&#xD;
      in the group Education will be invited to perform aquatic therapy and patients in group&#xD;
      aquatic therapy will receive the manual of educational guidelines.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">February 2015</start_date>
  <completion_date type="Actual">June 2016</completion_date>
  <primary_completion_date type="Actual">June 2016</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>Triple (Participant, Investigator, Outcomes Assessor)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Pain</measure>
    <time_frame>up to 3 months</time_frame>
    <description>Evaluation of pain - EVA</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Function</measure>
    <time_frame>2 and 3 months</time_frame>
    <description>Physical Function - WOMAC Index</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Balance</measure>
    <time_frame>2 and 3 months</time_frame>
    <description>ABC Scale and postural balance</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Quality Of Live</measure>
    <time_frame>2 and 3 months</time_frame>
    <description>SF-36 Questionaire</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>kinetic</measure>
    <time_frame>2 and 3 months</time_frame>
    <description>Ground Reaction Forces and postural balance</description>
  </secondary_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Actual">60</enrollment>
  <condition>Osteoarthritis</condition>
  <arm_group>
    <arm_group_label>Patient Education</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Health Education.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Aquatic Physical Therapy</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>Protocol of aquatic physical therapy exercises.</description>
  </arm_group>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Patient Education</intervention_name>
    <description>The educational program will comprise a multidisciplinary team: doctor, pharmacist, nurse, nutritionist, psychologist, physiotherapist and physical educator. Classes will be weekly in groups for eight weeks, with a duration of two hours.&#xD;
The education program will include the following items: guidelines about the disease and its complications, strategies for pain management (pharmacological and cognitive), physical exercise, nutrition and weight control, medication (type, interactions, current trends, side effects ), balance, proprioception, fall prevention, coping with chronic pain.</description>
    <arm_group_label>Patient Education</arm_group_label>
    <other_name>Health Education</other_name>
  </intervention>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>Aquatic Physical Therapy</intervention_name>
    <description>The exercise protocol will consist of: five minutes of heating with walking and patellar mobilization; ten minutes stretching the muscles of the lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps and hamstrings); ten minutes isometric and dynamic exercises with elastic (quadriceps, gluteus, adductors and abductors of hip sural triceps and hamstrings); twenty minutes away from aerobic exercise (stationary running deep running water); ten minutes in functional training step and proprioceptive exercises; and five minutes of cooling with stretching of muscles of lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps and hamstrings).</description>
    <arm_group_label>Aquatic Physical Therapy</arm_group_label>
    <other_name>Aquatic Exercise</other_name>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  patients aged between 60 and 85 years;&#xD;
&#xD;
          -  patients with knee OA by a physician confirmed by the criteria of American College of&#xD;
             Rheumatology;&#xD;
&#xD;
          -  patients with clinical and cognitive activities for the realization of the pool&#xD;
             conditions, confirmed by the Mini-Exam Mental state.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  patients undergoing surgical procedures in the last six months;&#xD;
&#xD;
          -  patients with chronic diseases such as coronary, other rheumatic diseases such as&#xD;
             rheumatoid arthritis; serious diseases such as cancer; chronic obstructive pulmonary&#xD;
             diseases; uncontrolled hypertensive;&#xD;
&#xD;
          -  patients unable to walk without aid equipment;&#xD;
&#xD;
          -  patients who have contraindications to practice exercises;&#xD;
&#xD;
          -  patients who have contraindications for entry into the pool, such as urinary or fecal&#xD;
             incontinence and skin problems;&#xD;
&#xD;
          -  patients participating in nutrition programs or physical activity in the last two&#xD;
             months (or resisted aerobic activity more than once a week for at least two months);&#xD;
&#xD;
          -  patients with metal implants in the lower limbs;&#xD;
&#xD;
          -  patients with morbid obesity (body mass index (BMI)&gt; 40 kg / m 2);&#xD;
&#xD;
          -  Patients unable to continue the study by programmed change of address or&#xD;
             hospitalization.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>60 Years</minimum_age>
    <maximum_age>85 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Ligia M Facci, PT, PhD</last_name>
    <role>Principal Investigator</role>
    <affiliation>Adjunct Professor</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Aquatic Physical Therapy Center &quot;Paulo A. Seibert&quot;</name>
      <address>
        <city>Londrina</city>
        <state>Pr</state>
        <zip>86038440</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Brazil</country>
  </location_countries>
  <reference>
    <citation>Lyytinen T, Liikavainio T, Bragge T, Hakkarainen M, Karjalainen PA, Arokoski JP. Postural control and thigh muscle activity in men with knee osteoarthritis. J Electromyogr Kinesiol. 2010 Dec;20(6):1066-74. doi: 10.1016/j.jelekin.2010.05.005. Epub 2010 Jun 11.</citation>
    <PMID>20541439</PMID>
  </reference>
  <reference>
    <citation>Price DD, McGrath PA, Rafii A, Buckingham B. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain. 1983 Sep;17(1):45-56. doi: 10.1016/0304-3959(83)90126-4.</citation>
    <PMID>6226917</PMID>
  </reference>
  <reference>
    <citation>Fernandes MI. Tradução e validação do questionário de qualidade de vida específico para osteoartrose WOMAC (Western Ontario McMasterUniversities) para a língua portuguesa. São Paulo, 2002. 103p. Tese de Mestrado - Universidade Federal de São Paulo - Escola Paulista de Medicina - Reumatologia.</citation>
  </reference>
  <reference>
    <citation>Marques AP, Mendes YC, Taddei U, Pereira CA, Assumpcao A. Brazilian-Portuguese translation and cross cultural adaptation of the activities-specific balance confidence (ABC) scale. Braz J Phys Ther. 2013 Mar-Apr;17(2):170-8. doi: 10.1590/S1413-35552012005000072.</citation>
    <PMID>23778771</PMID>
  </reference>
  <reference>
    <citation>Duarte M, Freitas SMSF. Revisão sobre posturografia baseada em plataforma de força para avaliação do equilíbrio. Rev Bras Fisioter, São Carlos, v. 14, n. 3, p. 183-92, maio/jun. 2010.</citation>
  </reference>
  <reference>
    <citation>CICONELLI RM, FERRAZ MB, SANTOS W, MEINÃO I, QUARESMA MR. Tradução para a língua portuguesa e validação do questionário genérico de avaliação da qualidade de vida SF-36 (Brasil SF-36).RevBrasreumatol 1999; 39(3): 143-150.</citation>
  </reference>
  <verification_date>May 2017</verification_date>
  <study_first_submitted>September 21, 2014</study_first_submitted>
  <study_first_submitted_qc>September 23, 2014</study_first_submitted_qc>
  <study_first_posted type="Estimate">September 25, 2014</study_first_posted>
  <last_update_submitted>May 23, 2017</last_update_submitted>
  <last_update_submitted_qc>May 23, 2017</last_update_submitted_qc>
  <last_update_posted type="Actual">May 25, 2017</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>Universidade Estadual de Londrina</investigator_affiliation>
    <investigator_full_name>Jefferson Rosa Cardoso</investigator_full_name>
    <investigator_title>Ligia Maria Facci</investigator_title>
  </responsible_party>
  <keyword>Osteoarthritis</keyword>
  <keyword>Patient Education</keyword>
  <keyword>Aquatic Exercise</keyword>
  <keyword>kinetic</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Osteoarthritis</mesh_term>
    <mesh_term>Osteoarthritis, Knee</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>Yes</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT02247882
org study id: RCTOA14
secondary id: 1406
nct id: NCT02247882
lead sponsor: 
collaborator: 
collaborator: 
has dmc: Yes
is fda regulated drug: No
is fda regulated device: No
The purpose of this study is to determine whether education or aquatic physical therapy are
      effective in the treatment of osteoarthritis in Knee due to intensity of pain, function
      capacity, quality of life and kinetic.
Sixty patients will be recruited from clinics and through printed newspaper. Physicians who
      routinely evaluate patients with this diagnosis will be informed of the study, and the same
      will be announced by television call.

      After passing a medical examination confirming the clinical diagnosis of knee osteoarthritis
      by American College of Rheumatology and other criteria, the elect will be informed of the
      objectives of the study and invited to participate.

      After evaluation of the records of referrals of knee OA, patients receive phone calls, will
      be informed of the research objectives, questioned regarding the inclusion and exclusion
      criteria of the study and invited to participate in the study.

      Upon study entry, personal information (name, age, gender, address and telephone) will be
      confirmed by a secretary, who will give the registration number of the patient. Personal
      information, as well as their radiographs, will be kept in personal form, with number of
      study enrollment.

      Before and after implementation of treatment protocols, as well as after three months, all
      patients will be assessed by an independent examiner, ie, that have no knowledge about the
      intervention with respect to different variables. The independent examiner will have been
      previously trained for this role to become fit to do so.

      Individuals will be assessed using the rubric for the outcomes of pain intensity using a
      Visual Analogue Scale (VAS); functional capacity of the Western Ontario and McMaster
      Universities Index (WOMAC); balance the Activities-specific Balance Confidence (ABC) and by
      static posturography and reaction forces to the ground by static force platform. Body weight
      will be checked by portable scale; height, and waist circumference with tape measure to
      calculate BMI.

      After evaluation, patients will be divided by the numbers generated by the computer through
      the site (www.random.org) in both treatment groups with 30 patients. After the generation of
      numbers, they will be transformed into a card with the assigned treatment (1- Patient
      Education; 2 Aquatic Physiotherapy) and then placed in sealed, opaque, sequentially numbered
      envelopes. Thus, it prevented the evaluator and the therapist choose the group to which the
      patient is assigned. Procedures for randomization and allocation, as well as assessments and
      interventions will be blinded.

      The educational program will comprise a multidisciplinary team: doctor, pharmacist, nurse,
      nutritionist, psychologist, physiotherapist and physical educator. Classes will be weekly in
      groups for eight weeks, lasting two hours, to be held in the Parlor of Our Lady of Grace
      Church, belonging to the scope of the Health Unit Vila Brazil.

      The program will include education, following the suggestions of Coleman et al. the following
      items: guidelines about the disease and its complications, strategies for pain management
      (pharmacological and cognitive), physical exercise, nutrition and weight control, medication
      (type, interactions, current trends, side effects), balance, proprioception , fall
      prevention, coping with chronic pain. Following, practical activities on the themes will be
      addressed.

      To enhance the information at the end, patients will receive printed material with the
      guidelines given by the professional. Still, the first and last day of the education program,
      patients will respond a questionnaire addressing their knowledge about the disease developed
      by the researchers.

      Supervised aquatic exercise will run individually, twice a week, lasting 60 minutes, for
      eight weeks, totaling 16 sessions at the Center for Aquatic Physical Therapy Professor Paulo
      Armindo Seibert, Universidade Estadual de Londrina. The water temperature will be maintained
      at approximately 32 degrees, with a depth of 1.20m. The exercise protocol will consist of:
      five minutes of heating with walking and patellar mobilization; ten minutes stretching the
      muscles of the lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps
      and hamstrings); ten minutes isometric and dynamic exercises with elastic (quadriceps,
      gluteus, adductors and abductors of hip sural triceps and hamstrings); twenty minutes away
      from aerobic exercise (stationary running deep water running); ten minutes in functional
      training step and proprioceptive exercises; and five minutes of cooling with stretching of
      muscles of lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps and
      hamstrings).

      Both groups will receive guidance home exercises two to three times a week, and reinforced by
      familiar previously illustrated booklets, which include the same goals of aquatic exercises:
      heating, self stretching of the lower limb muscles, isometric and dynamic exercises of the
      lower limbs , proprioceptive and functional exercises, aerobic exercises is relaxation.

      Three months after the end of intervention protocols, ie, at the end of follow-up, patients
      in the group Education will be invited to perform aquatic therapy and patients in group
      aquatic therapy will receive the manual of educational guidelines.
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Treatment
masking: Triple (Participant, Investigator, Outcomes Assessor)
measure: Pain
time frame: up to 3 months
description: Evaluation of pain - EVA
measure: Function
time frame: 2 and 3 months
description: Physical Function - WOMAC Index
measure: Balance
time frame: 2 and 3 months
description: ABC Scale and postural balance
measure: Quality Of Live
time frame: 2 and 3 months
description: SF-36 Questionaire
measure: kinetic
time frame: 2 and 3 months
description: Ground Reaction Forces and postural balance
arm group label: Patient Education
arm group type: Experimental
description: Health Education.
arm group label: Aquatic Physical Therapy
arm group type: Active Comparator
description: Protocol of aquatic physical therapy exercises.
intervention type: Other
intervention name: Patient Education
description: The educational program will comprise a multidisciplinary team: doctor, pharmacist, nurse, nutritionist, psychologist, physiotherapist and physical educator. Classes will be weekly in groups for eight weeks, with a duration of two hours.
The education program will include the following items: guidelines about the disease and its complications, strategies for pain management (pharmacological and cognitive), physical exercise, nutrition and weight control, medication (type, interactions, current trends, side effects ), balance, proprioception, fall prevention, coping with chronic pain.
arm group label: Patient Education
other name: Health Education
intervention type: Other
intervention name: Aquatic Physical Therapy
description: The exercise protocol will consist of: five minutes of heating with walking and patellar mobilization; ten minutes stretching the muscles of the lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps and hamstrings); ten minutes isometric and dynamic exercises with elastic (quadriceps, gluteus, adductors and abductors of hip sural triceps and hamstrings); twenty minutes away from aerobic exercise (stationary running deep running water); ten minutes in functional training step and proprioceptive exercises; and five minutes of cooling with stretching of muscles of lower limbs (quadriceps, gluteus, adductors and abductors of hip sural triceps and hamstrings).
arm group label: Aquatic Physical Therapy
other name: Aquatic Exercise
criteria: 
gender: All
minimum age: 60 Years
maximum age: 85 Years
healthy volunteers: No
last name: Ligia M Facci, PT, PhD
role: Principal Investigator
affiliation: Adjunct Professor
facility: 
country: Brazil
citation: Lyytinen T, Liikavainio T, Bragge T, Hakkarainen M, Karjalainen PA, Arokoski JP. Postural control and thigh muscle activity in men with knee osteoarthritis. J Electromyogr Kinesiol. 2010 Dec;20(6):1066-74. doi: 10.1016/j.jelekin.2010.05.005. Epub 2010 Jun 11.
PMID: 20541439
citation: Price DD, McGrath PA, Rafii A, Buckingham B. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain. 1983 Sep;17(1):45-56. doi: 10.1016/0304-3959(83)90126-4.
PMID: 6226917
citation: Fernandes MI. Tradução e validação do questionário de qualidade de vida específico para osteoartrose WOMAC (Western Ontario McMasterUniversities) para a língua portuguesa. São Paulo, 2002. 103p. Tese de Mestrado - Universidade Federal de São Paulo - Escola Paulista de Medicina - Reumatologia.
citation: Marques AP, Mendes YC, Taddei U, Pereira CA, Assumpcao A. Brazilian-Portuguese translation and cross cultural adaptation of the activities-specific balance confidence (ABC) scale. Braz J Phys Ther. 2013 Mar-Apr;17(2):170-8. doi: 10.1590/S1413-35552012005000072.
PMID: 23778771
citation: Duarte M, Freitas SMSF. Revisão sobre posturografia baseada em plataforma de força para avaliação do equilíbrio. Rev Bras Fisioter, São Carlos, v. 14, n. 3, p. 183-92, maio/jun. 2010.
citation: CICONELLI RM, FERRAZ MB, SANTOS W, MEINÃO I, QUARESMA MR. Tradução para a língua portuguesa e validação do questionário genérico de avaliação da qualidade de vida SF-36 (Brasil SF-36).RevBrasreumatol 1999; 39(3): 143-150.
responsible party type: Principal Investigator
investigator affiliation: Universidade Estadual de Londrina
investigator full name: Jefferson Rosa Cardoso
investigator title: Ligia Maria Facci
mesh term: Osteoarthritis
mesh term: Osteoarthritis, Knee
sharing ipd: Yes