<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT02229305</url>
  </required_header>
  <id_info>
    <org_study_id>STEPs Phase III</org_study_id>
    <nct_id>NCT02229305</nct_id>
  </id_info>
  <brief_title>Maine Implementation Study - Phase III</brief_title>
  <official_title>Child System and Treatment Enhancement Projects (Child STEPs); The Clinic Treatment Project in Maine - Phase III</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Harvard University</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
    <collaborator>
      <agency>MacArthur Foundation</agency>
      <agency_class>Other</agency_class>
    </collaborator>
    <collaborator>
      <agency>Casey Family Programs</agency>
      <agency_class>Other</agency_class>
    </collaborator>
    <collaborator>
      <agency>Annie E. Casey Foundation</agency>
      <agency_class>Other</agency_class>
    </collaborator>
  </sponsors>
  <source>Harvard University</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      This study focused on youths who were referred to community-based mental healths clinics for&#xD;
      problems related to disruptive behaviors, depression, anxiety, traumatic stress, and any&#xD;
      combination of these problems. Therapists were randomly assigned to deliver usual treatment&#xD;
      procedures (usual care, or UC) in their clinics or an evidence-based, modularized treatment&#xD;
      (Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct&#xD;
      Problems, or MATCH-ADTC). Assessments were conducted at pre-treatment and post-treatment, and&#xD;
      every 3 to 6 months for two years. Results will address critical questions about deployment&#xD;
      of evidence-based youth practices to clinical settings.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      This study focused on youths aged 6 - 15 who were referred to community-based mental healths&#xD;
      clinics for problems related to disruptive behaviors, depression, anxiety, traumatic stress,&#xD;
      and any combination of these problems. Using a randomized block design, therapists were&#xD;
      randomly assigned to deliver usual treatment procedures (usual care, or UC) in their clinics&#xD;
      or an evidence-based, modularized treatment (Modular Approach to Therapy for Children with&#xD;
      Anxiety, Depression, Trauma, or Conduct Problems, or MATCH-ADTC). MATCH-ADTC was supported by&#xD;
      training and supervision procedures designed to fit providers and their clinic contexts.&#xD;
      Assessments were carried out at pre-treatment, at post-treatment, and at 3-,6-,9-,12,18-,and&#xD;
      24-month follow-ups. Assessments carried out at pre-treatment included (a) individual youth&#xD;
      problems and disorders; (b) individual youth functioning at home and school; and (c) clinic&#xD;
      staff beliefs and attitudes toward evidence-based treatments. Assessments carried out at&#xD;
      post-treatment and follow-ups included measures of (1) youth, caregiver, and therapist&#xD;
      satisfaction with treatment; (b) youth, caregiver, and therapist views on the quality of the&#xD;
      therapeutic relationship; and (c) treatment costs. Assessments carried out at follow-up only&#xD;
      included measures of (a) caregiver reports of any mental health service use following project&#xD;
      treatment; (b) therapist reports on the extent to which the treatment procedures they used in&#xD;
      the project are continued after project termination. Analyses will address critical questions&#xD;
      about deployment of evidence-based youth practices to clinical settings.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Completed</overall_status>
  <start_date>December 2008</start_date>
  <completion_date type="Actual">October 2012</completion_date>
  <primary_completion_date type="Actual">October 2012</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>Triple (Participant, Care Provider, Outcomes Assessor)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Brief Problem Checklist (BPC, parent and child forms)</measure>
    <time_frame>Change over time from Day 1 to Day 242 (end of treatment)</time_frame>
    <description>Youth and parents were contacted weekly to report changes in youth functioning. Each person was asked to rate their own or their child's behavior on 12 items (6 internalizing and 6 externalizing behaviors) that were adapted from the Youth Self Report and the Child Behavior Checklist. Children and caregivers completed the pre-treatment assessment on Day 1, every week during treatment, and at post-treatment assessment which occurred on average 242days (SD = 121 days) after the pre-treatment assessment.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Top Problems Assessment</measure>
    <time_frame>Change over time from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>Youths and parents were asked to identify &quot;The three most important problems for which you need [or &quot;your child needs&quot;] help.&quot; at the intake assessment. The six resulting problems (3 from youth, 3 from parent) were then rated on a scale of 0 (&quot;Not serious at all&quot;) to 10 (&quot;Very serious problem&quot;) by youth and parent. Youths and parents completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 242 days (SD = 121 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1. (Used as a measure of clinical outcome.)</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>UCLA PTSD Index</measure>
    <time_frame>Change over time from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>The PTSD Index is a 38-item questionnaire that is widely-used to assess post-traumatic stress symptoms in children. Part I is a brief lifetime trauma screen. If a significant trauma is identified, Part II assesses DSM-IV PTSD symptoms related to the trauma. Part III assesses frequency of post-traumatic stress symptoms during the past month. The measure has shown good convergent validity, strong test-retest reliability, and Cronbach's alpha values in the .90s. We will administer it separately to students and their caregivers at pre-treatment, to determine whether post-traumatic stress should be a focus of treatment, and we will re-administer it at post-treatment and follow-up to assess change over time. Youths and parents completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 242 days (SD = 121 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1. (Used as a measure of clinical outcome.)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Youth Self Report (YSR)</measure>
    <time_frame>Change over time from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>The YSR assesses problems in children on eight narrow-band scales (Withdrawn, Somatic Complaints, Anxious, Social Problems, Thought Problems, Attention Problems, Rule-Breaking Behavior, Aggressive Behavior), three broad-band scales (Internalizing, Externalizing, and Total problems), and six DSM-oriented scales. Children completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 242 days (SD = 121 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1.(Used as a measure of clinical outcome.)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Child Behavior Checklist</measure>
    <time_frame>Change over time from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>The CBCL assesses problems in children on eight narrow-band scales (Withdrawn, Somatic Complaints, Anxious, Social Problems, Thought Problems, Attention Problems, Rule-Breaking Behavior, Aggression), three broad-band scales (Internalizing, Externalizing, and Total problems), and six DSM-oriented scales. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1. (Used as a measure of clinical outcome.)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Therapeutic Alliance Scale for Children</measure>
    <time_frame>Post-treatment (Day 267)</time_frame>
    <description>The quality of youths' working alliance with their therapists was assessed via the Therapeutic Alliance Scale for Children (TASC, Shirk &amp; Saiz, 1992). The 7-item scale comes in both a youth-report form and a parent-report form (parents reporting on their youth's relationship with the therapist). On average, children and caregivers completed the post-treatment assessment 267 days (SD = 124 days) after the pre-treatment assessment. (Available for supplemental analyses.)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Service Assessment for Children and Adolescents: Treatment and Auxiliary Service Use Scales</measure>
    <time_frame>Change over tiem from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>The SACA (Horwitz et al., 2001)is a standardized interview for youths and parents that measures use of mental health services across a broad spectrum (including outpatient, inpatient, and school-based). SACA reliability and validity data are well-documented. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 12- and 24-month follow-up from Day 1.(Available for supplemental analyses.)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Brief Impairment Scale</measure>
    <time_frame>Change over time from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>The BIS is a 23-item instrument that evaluates three domains of functioning: interpersonal relations, school/work functioning, and self-care/self-fulfillment. Its advantages over other global impairment instruments are that it is respondent based, short in administration time, and multidimensional. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 12- and 24-month follow-up from Day 1.(Available for supplemental analyses.)</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Services for Children and Adolescents - Parent Interview (SCAPI)</measure>
    <time_frame>Change over time from Day 1 to Day 735 (24-month follow-up)</time_frame>
    <description>The SCAPI is a measure that tracks child's use of medication as reported by the parent. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1.(Available for supplemental analyses.)</description>
  </secondary_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Actual">235</enrollment>
  <condition>Anxiety</condition>
  <condition>Trauma</condition>
  <condition>Depression</condition>
  <condition>Problem Behavior</condition>
  <arm_group>
    <arm_group_label>Usual Care Treatment</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>Usual Care therapists could use any treatment procedures they used regularly in their clinical practice.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Modular Approach to Therapy for Children</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Therapists used a modular manual (Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems; Chorpita &amp; Weisz, 2010) to help children with primary problems of anxiety, depression, trauma, and conduct.</description>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Usual Care Treatment</intervention_name>
    <description>Usual Care therapists could use any treatment procedures they used regularly in their clinical practice.</description>
    <arm_group_label>Usual Care Treatment</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Modular Approach to Therapy for Children</intervention_name>
    <description>Therapists used the Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems (MATCH-ADTC; Chorpita &amp; Weisz, 2010).</description>
    <arm_group_label>Modular Approach to Therapy for Children</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  6 - 15 year old and their caregivers&#xD;
&#xD;
          -  seeking services at community mental health clinics&#xD;
&#xD;
          -  primary problem or disorder related to anxiety, traumatic stress, depression, or&#xD;
             conduct problems, or any combination of the four problems&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Child is younger than 6 years or older than 15 years on the day of the phone screen&#xD;
&#xD;
          -  Child has attempted suicide within the past year&#xD;
&#xD;
          -  Schizophrenic spectrum disorders (including MDD with psychotic features)&#xD;
&#xD;
          -  Autism or another Pervasive Developmental Disorder (E.g., PDD NOS, Asperger's&#xD;
             Disorder, Child Disintegration Disorder, Rett's Disorder)&#xD;
&#xD;
          -  Anorexia Nervosa&#xD;
&#xD;
          -  Bulimia Nervosa&#xD;
&#xD;
          -  Mental Retardation&#xD;
&#xD;
          -  No relevant T-scores validate target disorders&#xD;
&#xD;
          -  ADHD identified as primary reason for seeking treatment at phone screen&#xD;
&#xD;
          -  Child's medication has not been regulated for one month or longer&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>6 Years</minimum_age>
    <maximum_age>15 Years</maximum_age>
    <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>John R Weisz, PhD</last_name>
    <role>Principal Investigator</role>
    <affiliation>Harvard University</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Judge Baker Children's Center</name>
      <address>
        <city>Boston</city>
        <state>Massachusetts</state>
        <zip>02120</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>United States</country>
  </location_countries>
  <link>
    <url>http://www.child-steps.org/</url>
    <description>Child System and Treatment Enhancement Projects</description>
  </link>
  <reference>
    <citation>Chorpita BF, Bernstein A, Daleiden EL; Research Network on Youth Mental Health. Driving with roadmaps and dashboards: using information resources to structure the decision models in service organizations. Adm Policy Ment Health. 2008 Mar;35(1-2):114-23. doi: 10.1007/s10488-007-0151-x. Epub 2007 Nov 6.</citation>
    <PMID>17987376</PMID>
  </reference>
  <reference>
    <citation>Borntrager CF, Chorpita BF, Higa-McMillan C, Weisz JR. Provider attitudes toward evidence-based practices: are the concerns with the evidence or with the manuals? Psychiatr Serv. 2009 May;60(5):677-81. doi: 10.1176/ps.2009.60.5.677.</citation>
    <PMID>19411357</PMID>
  </reference>
  <reference>
    <citation>Ebesutani C, Bernstein A, Nakamura BJ, Chorpita BF, Higa-McMillan CK, Weisz JR; The Research Network on Youth Mental Health. Concurrent Validity of the Child Behavior Checklist DSM-Oriented Scales: Correspondence with DSM Diagnoses and Comparison to Syndrome Scales. J Psychopathol Behav Assess. 2010 Sep;32(3):373-384. doi: 10.1007/s10862-009-9174-9. Epub 2009 Nov 27.</citation>
    <PMID>20700377</PMID>
  </reference>
  <reference>
    <citation>Chorpita BF, Reise S, Weisz JR, Grubbs K, Becker KD, Krull JL; Research Network on Youth Mental Health. Evaluation of the Brief Problem Checklist: child and caregiver interviews to measure clinical progress. J Consult Clin Psychol. 2010 Aug;78(4):526-36. doi: 10.1037/a0019602.</citation>
    <PMID>20658809</PMID>
  </reference>
  <reference>
    <citation>Ebesutani C, Chorpita BF, Higa-McMillan CK, Nakamura BJ, Regan J, Lynch RE. A psychometric analysis of the Revised Child Anxiety and Depression Scales--parent version in a school sample. J Abnorm Child Psychol. 2011 Feb;39(2):173-85. doi: 10.1007/s10802-010-9460-8.</citation>
    <PMID>20878460</PMID>
  </reference>
  <reference>
    <citation>Palinkas LA, Schoenwald SK, Hoagwood K, Landsverk J, Chorpita BF, Weisz JR; Research Network on Youth Mental Health. An ethnographic study of implementation of evidence-based treatments in child mental health: first steps. Psychiatr Serv. 2008 Jul;59(7):738-46. doi: 10.1176/ps.2008.59.7.738.</citation>
    <PMID>18586990</PMID>
  </reference>
  <reference>
    <citation>Weisz JR, Chorpita BF, Palinkas LA, Schoenwald SK, Miranda J, Bearman SK, Daleiden EL, Ugueto AM, Ho A, Martin J, Gray J, Alleyne A, Langer DA, Southam-Gerow MA, Gibbons RD; Research Network on Youth Mental Health. Testing standard and modular designs for psychotherapy treating depression, anxiety, and conduct problems in youth: a randomized effectiveness trial. Arch Gen Psychiatry. 2012 Mar;69(3):274-82. doi: 10.1001/archgenpsychiatry.2011.147. Epub 2011 Nov 7.</citation>
    <PMID>22065252</PMID>
  </reference>
  <verification_date>August 2014</verification_date>
  <study_first_submitted>August 28, 2014</study_first_submitted>
  <study_first_submitted_qc>August 28, 2014</study_first_submitted_qc>
  <study_first_posted type="Estimate">September 1, 2014</study_first_posted>
  <last_update_submitted>August 28, 2014</last_update_submitted>
  <last_update_submitted_qc>August 28, 2014</last_update_submitted_qc>
  <last_update_posted type="Estimate">September 1, 2014</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>Harvard University</investigator_affiliation>
    <investigator_full_name>John Weisz</investigator_full_name>
    <investigator_title>Primary Investigator</investigator_title>
  </responsible_party>
  <keyword>Anxiety</keyword>
  <keyword>Trauma</keyword>
  <keyword>Depression</keyword>
  <keyword>Problem Behavior</keyword>
  <keyword>evidence-based treatments</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Depression</mesh_term>
    <mesh_term>Problem Behavior</mesh_term>
  </condition_browse>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT02229305
org study id: STEPs Phase III
nct id: NCT02229305
lead sponsor: 
collaborator: 
collaborator: 
collaborator: 
has dmc: Yes
This study focused on youths who were referred to community-based mental healths clinics for
      problems related to disruptive behaviors, depression, anxiety, traumatic stress, and any
      combination of these problems. Therapists were randomly assigned to deliver usual treatment
      procedures (usual care, or UC) in their clinics or an evidence-based, modularized treatment
      (Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct
      Problems, or MATCH-ADTC). Assessments were conducted at pre-treatment and post-treatment, and
      every 3 to 6 months for two years. Results will address critical questions about deployment
      of evidence-based youth practices to clinical settings.
This study focused on youths aged 6 - 15 who were referred to community-based mental healths
      clinics for problems related to disruptive behaviors, depression, anxiety, traumatic stress,
      and any combination of these problems. Using a randomized block design, therapists were
      randomly assigned to deliver usual treatment procedures (usual care, or UC) in their clinics
      or an evidence-based, modularized treatment (Modular Approach to Therapy for Children with
      Anxiety, Depression, Trauma, or Conduct Problems, or MATCH-ADTC). MATCH-ADTC was supported by
      training and supervision procedures designed to fit providers and their clinic contexts.
      Assessments were carried out at pre-treatment, at post-treatment, and at 3-,6-,9-,12,18-,and
      24-month follow-ups. Assessments carried out at pre-treatment included (a) individual youth
      problems and disorders; (b) individual youth functioning at home and school; and (c) clinic
      staff beliefs and attitudes toward evidence-based treatments. Assessments carried out at
      post-treatment and follow-ups included measures of (1) youth, caregiver, and therapist
      satisfaction with treatment; (b) youth, caregiver, and therapist views on the quality of the
      therapeutic relationship; and (c) treatment costs. Assessments carried out at follow-up only
      included measures of (a) caregiver reports of any mental health service use following project
      treatment; (b) therapist reports on the extent to which the treatment procedures they used in
      the project are continued after project termination. Analyses will address critical questions
      about deployment of evidence-based youth practices to clinical settings.
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Treatment
masking: Triple (Participant, Care Provider, Outcomes Assessor)
measure: Brief Problem Checklist (BPC, parent and child forms)
time frame: Change over time from Day 1 to Day 242 (end of treatment)
description: Youth and parents were contacted weekly to report changes in youth functioning. Each person was asked to rate their own or their child's behavior on 12 items (6 internalizing and 6 externalizing behaviors) that were adapted from the Youth Self Report and the Child Behavior Checklist. Children and caregivers completed the pre-treatment assessment on Day 1, every week during treatment, and at post-treatment assessment which occurred on average 242days (SD = 121 days) after the pre-treatment assessment.
measure: Top Problems Assessment
time frame: Change over time from Day 1 to Day 735 (24-month follow-up)
description: Youths and parents were asked to identify "The three most important problems for which you need [or "your child needs"] help." at the intake assessment. The six resulting problems (3 from youth, 3 from parent) were then rated on a scale of 0 ("Not serious at all") to 10 ("Very serious problem") by youth and parent. Youths and parents completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 242 days (SD = 121 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1. (Used as a measure of clinical outcome.)
measure: UCLA PTSD Index
time frame: Change over time from Day 1 to Day 735 (24-month follow-up)
description: The PTSD Index is a 38-item questionnaire that is widely-used to assess post-traumatic stress symptoms in children. Part I is a brief lifetime trauma screen. If a significant trauma is identified, Part II assesses DSM-IV PTSD symptoms related to the trauma. Part III assesses frequency of post-traumatic stress symptoms during the past month. The measure has shown good convergent validity, strong test-retest reliability, and Cronbach's alpha values in the .90s. We will administer it separately to students and their caregivers at pre-treatment, to determine whether post-traumatic stress should be a focus of treatment, and we will re-administer it at post-treatment and follow-up to assess change over time. Youths and parents completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 242 days (SD = 121 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1. (Used as a measure of clinical outcome.)
measure: Youth Self Report (YSR)
time frame: Change over time from Day 1 to Day 735 (24-month follow-up)
description: The YSR assesses problems in children on eight narrow-band scales (Withdrawn, Somatic Complaints, Anxious, Social Problems, Thought Problems, Attention Problems, Rule-Breaking Behavior, Aggressive Behavior), three broad-band scales (Internalizing, Externalizing, and Total problems), and six DSM-oriented scales. Children completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 242 days (SD = 121 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1.(Used as a measure of clinical outcome.)
measure: Child Behavior Checklist
time frame: Change over time from Day 1 to Day 735 (24-month follow-up)
description: The CBCL assesses problems in children on eight narrow-band scales (Withdrawn, Somatic Complaints, Anxious, Social Problems, Thought Problems, Attention Problems, Rule-Breaking Behavior, Aggression), three broad-band scales (Internalizing, Externalizing, and Total problems), and six DSM-oriented scales. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1. (Used as a measure of clinical outcome.)
measure: Therapeutic Alliance Scale for Children
time frame: Post-treatment (Day 267)
description: The quality of youths' working alliance with their therapists was assessed via the Therapeutic Alliance Scale for Children (TASC, Shirk & Saiz, 1992). The 7-item scale comes in both a youth-report form and a parent-report form (parents reporting on their youth's relationship with the therapist). On average, children and caregivers completed the post-treatment assessment 267 days (SD = 124 days) after the pre-treatment assessment. (Available for supplemental analyses.)
measure: Service Assessment for Children and Adolescents: Treatment and Auxiliary Service Use Scales
time frame: Change over tiem from Day 1 to Day 735 (24-month follow-up)
description: The SACA (Horwitz et al., 2001)is a standardized interview for youths and parents that measures use of mental health services across a broad spectrum (including outpatient, inpatient, and school-based). SACA reliability and validity data are well-documented. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 12- and 24-month follow-up from Day 1.(Available for supplemental analyses.)
measure: Brief Impairment Scale
time frame: Change over time from Day 1 to Day 735 (24-month follow-up)
description: The BIS is a 23-item instrument that evaluates three domains of functioning: interpersonal relations, school/work functioning, and self-care/self-fulfillment. Its advantages over other global impairment instruments are that it is respondent based, short in administration time, and multidimensional. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 12- and 24-month follow-up from Day 1.(Available for supplemental analyses.)
measure: Services for Children and Adolescents - Parent Interview (SCAPI)
time frame: Change over time from Day 1 to Day 735 (24-month follow-up)
description: The SCAPI is a measure that tracks child's use of medication as reported by the parent. Caregivers completed the pre-treatment assessment on Day 1, at post-treatment assessment which occurred on average 267 days (SD = 124 days) after the pre-treatment assessment, and at 3-, 6-, 9-, 12- and 24-month follow-up from Day 1.(Available for supplemental analyses.)
arm group label: Usual Care Treatment
arm group type: Active Comparator
description: Usual Care therapists could use any treatment procedures they used regularly in their clinical practice.
arm group label: Modular Approach to Therapy for Children
arm group type: Experimental
description: Therapists used a modular manual (Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems; Chorpita & Weisz, 2010) to help children with primary problems of anxiety, depression, trauma, and conduct.
intervention type: Behavioral
intervention name: Usual Care Treatment
description: Usual Care therapists could use any treatment procedures they used regularly in their clinical practice.
arm group label: Usual Care Treatment
intervention type: Behavioral
intervention name: Modular Approach to Therapy for Children
description: Therapists used the Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems (MATCH-ADTC; Chorpita & Weisz, 2010).
arm group label: Modular Approach to Therapy for Children
criteria: 
gender: All
minimum age: 6 Years
maximum age: 15 Years
healthy volunteers: Accepts Healthy Volunteers
last name: John R Weisz, PhD
role: Principal Investigator
affiliation: Harvard University
facility: 
country: United States
url: http://www.child-steps.org/
description: Child System and Treatment Enhancement Projects
citation: Chorpita BF, Bernstein A, Daleiden EL; Research Network on Youth Mental Health. Driving with roadmaps and dashboards: using information resources to structure the decision models in service organizations. Adm Policy Ment Health. 2008 Mar;35(1-2):114-23. doi: 10.1007/s10488-007-0151-x. Epub 2007 Nov 6.
PMID: 17987376
citation: Borntrager CF, Chorpita BF, Higa-McMillan C, Weisz JR. Provider attitudes toward evidence-based practices: are the concerns with the evidence or with the manuals? Psychiatr Serv. 2009 May;60(5):677-81. doi: 10.1176/ps.2009.60.5.677.
PMID: 19411357
citation: Ebesutani C, Bernstein A, Nakamura BJ, Chorpita BF, Higa-McMillan CK, Weisz JR; The Research Network on Youth Mental Health. Concurrent Validity of the Child Behavior Checklist DSM-Oriented Scales: Correspondence with DSM Diagnoses and Comparison to Syndrome Scales. J Psychopathol Behav Assess. 2010 Sep;32(3):373-384. doi: 10.1007/s10862-009-9174-9. Epub 2009 Nov 27.
PMID: 20700377
citation: Chorpita BF, Reise S, Weisz JR, Grubbs K, Becker KD, Krull JL; Research Network on Youth Mental Health. Evaluation of the Brief Problem Checklist: child and caregiver interviews to measure clinical progress. J Consult Clin Psychol. 2010 Aug;78(4):526-36. doi: 10.1037/a0019602.
PMID: 20658809
citation: Ebesutani C, Chorpita BF, Higa-McMillan CK, Nakamura BJ, Regan J, Lynch RE. A psychometric analysis of the Revised Child Anxiety and Depression Scales--parent version in a school sample. J Abnorm Child Psychol. 2011 Feb;39(2):173-85. doi: 10.1007/s10802-010-9460-8.
PMID: 20878460
citation: Palinkas LA, Schoenwald SK, Hoagwood K, Landsverk J, Chorpita BF, Weisz JR; Research Network on Youth Mental Health. An ethnographic study of implementation of evidence-based treatments in child mental health: first steps. Psychiatr Serv. 2008 Jul;59(7):738-46. doi: 10.1176/ps.2008.59.7.738.
PMID: 18586990
citation: Weisz JR, Chorpita BF, Palinkas LA, Schoenwald SK, Miranda J, Bearman SK, Daleiden EL, Ugueto AM, Ho A, Martin J, Gray J, Alleyne A, Langer DA, Southam-Gerow MA, Gibbons RD; Research Network on Youth Mental Health. Testing standard and modular designs for psychotherapy treating depression, anxiety, and conduct problems in youth: a randomized effectiveness trial. Arch Gen Psychiatry. 2012 Mar;69(3):274-82. doi: 10.1001/archgenpsychiatry.2011.147. Epub 2011 Nov 7.
PMID: 22065252
responsible party type: Principal Investigator
investigator affiliation: Harvard University
investigator full name: John Weisz
investigator title: Primary Investigator
mesh term: Depression
mesh term: Problem Behavior