<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT01672281</url>
  </required_header>
  <id_info>
    <org_study_id>vbx</org_study_id>
    <nct_id>NCT01672281</nct_id>
  </id_info>
  <brief_title>vibroX-training in Endurance Trained Men</brief_title>
  <official_title>Influence of vibroX-training on the Power-duration-relationship and Maximal Force in Relation to Conventional Resistance Training in Endurance Trained Men</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>University of Zurich</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>University of Zurich</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      In endurance sports competitions such as cycling, an athlete's capacity to sustain submaximum&#xD;
      power (i.e. endurance capacity) strongly influences overall race performance. Endurance&#xD;
      capacity can be increased by both long, continuous endurance exercise at moderate oxygen&#xD;
      consumption, and high-intensity (at or above peak oxygen consumption) interval training.&#xD;
      However, it has also been shown that resistance exercise, if performed in addition to&#xD;
      endurance exercise, can further enhance endurance capacity. The investigators have recently&#xD;
      described a novel training method, which is based on combined vibration and resistance&#xD;
      training and superimposed vascular occlusion. Based on the investigators previous results&#xD;
      showing that this type of training leads to marked increases in endurance capacity in&#xD;
      previously untrained young women, the investigators aim at investigating whether the method&#xD;
      is also effective in increasing endurance capacity in highly endurance-trained young men, and&#xD;
      whether the method leads to bigger improvements relative to resistance exercise alone.&#xD;
      Besides the functional outcomes the investigators are also interested in the specificity of&#xD;
      the cellular adaptations with respect to the two trainings methods.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Completed</overall_status>
  <start_date>November 2011</start_date>
  <completion_date type="Actual">December 2012</completion_date>
  <primary_completion_date type="Actual">September 2012</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Change from baseline in Critical Power</measure>
    <time_frame>2 month intervention</time_frame>
    <description>The difference in changes in Critical Power [Watts] are compared between the vibrox- and resistance training group. For this purpose, participants complete pre and post training a cycling ramp test and 4 cycling constant load tests.</description>
  </primary_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Actual">30</enrollment>
  <condition>Health Behavior</condition>
  <arm_group>
    <arm_group_label>vibrox training</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
  </arm_group>
  <arm_group>
    <arm_group_label>resistance training</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
  </arm_group>
  <intervention>
    <intervention_type>Other</intervention_type>
    <intervention_name>vibrox- vs. resistance training</intervention_name>
    <description>Comparison between two exercise interventions</description>
    <arm_group_label>resistance training</arm_group_label>
    <arm_group_label>vibrox training</arm_group_label>
    <other_name>vibrox</other_name>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion criteria:&#xD;
&#xD;
          -  male&#xD;
&#xD;
          -  no fever / no common cold at the beginning of the study&#xD;
&#xD;
          -  at least 4 endurance training sessions prior to beginning of study&#xD;
&#xD;
          -  age 18-35y&#xD;
&#xD;
          -  non-smoker&#xD;
&#xD;
          -  no cardiological / orthopedic problems&#xD;
&#xD;
          -  no pacemaker&#xD;
&#xD;
          -  fulfills health questionnaire's requirements&#xD;
&#xD;
        Exclusion criteria: female&#xD;
&#xD;
          -  fever / common cold at beginning of study&#xD;
&#xD;
          -  untrained condition (less than 4 endurance training sessions prior to the&#xD;
&#xD;
          -  beginning of the study)&#xD;
&#xD;
          -  age under 18 oder above 35y&#xD;
&#xD;
          -  smoker&#xD;
&#xD;
          -  cardiovascular or orthopedic problems&#xD;
&#xD;
          -  cardiac pacemaker&#xD;
&#xD;
          -  does not fulfill health questionnaire's requirements&#xD;
      </textblock>
    </criteria>
    <gender>Male</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>35 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Hans H. Jung, Professor MD</last_name>
    <role>Principal Investigator</role>
    <affiliation>University Hospital Zurich, Division of Neurology</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>University Hospital Zurich, Division of Neurology</name>
      <address>
        <city>Zurich</city>
        <state>ZH</state>
        <zip>8091 Zurich</zip>
        <country>Switzerland</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Switzerland</country>
  </location_countries>
  <verification_date>May 2013</verification_date>
  <study_first_submitted>May 25, 2012</study_first_submitted>
  <study_first_submitted_qc>August 21, 2012</study_first_submitted_qc>
  <study_first_posted type="Estimate">August 24, 2012</study_first_posted>
  <last_update_submitted>May 13, 2013</last_update_submitted>
  <last_update_submitted_qc>May 13, 2013</last_update_submitted_qc>
  <last_update_posted type="Estimate">May 14, 2013</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT01672281
org study id: vbx
nct id: NCT01672281
lead sponsor: 
has dmc: No
In endurance sports competitions such as cycling, an athlete's capacity to sustain submaximum
      power (i.e. endurance capacity) strongly influences overall race performance. Endurance
      capacity can be increased by both long, continuous endurance exercise at moderate oxygen
      consumption, and high-intensity (at or above peak oxygen consumption) interval training.
      However, it has also been shown that resistance exercise, if performed in addition to
      endurance exercise, can further enhance endurance capacity. The investigators have recently
      described a novel training method, which is based on combined vibration and resistance
      training and superimposed vascular occlusion. Based on the investigators previous results
      showing that this type of training leads to marked increases in endurance capacity in
      previously untrained young women, the investigators aim at investigating whether the method
      is also effective in increasing endurance capacity in highly endurance-trained young men, and
      whether the method leads to bigger improvements relative to resistance exercise alone.
      Besides the functional outcomes the investigators are also interested in the specificity of
      the cellular adaptations with respect to the two trainings methods.
allocation: Randomized
intervention model: Parallel Assignment
masking: None (Open Label)
measure: Change from baseline in Critical Power
time frame: 2 month intervention
description: The difference in changes in Critical Power [Watts] are compared between the vibrox- and resistance training group. For this purpose, participants complete pre and post training a cycling ramp test and 4 cycling constant load tests.
arm group label: vibrox training
arm group type: Experimental
arm group label: resistance training
arm group type: Experimental
intervention type: Other
intervention name: vibrox- vs. resistance training
description: Comparison between two exercise interventions
arm group label: resistance training
arm group label: vibrox training
other name: vibrox
criteria: 
gender: Male
minimum age: 18 Years
maximum age: 35 Years
healthy volunteers: No
last name: Hans H. Jung, Professor MD
role: Principal Investigator
affiliation: University Hospital Zurich, Division of Neurology
facility: 
country: Switzerland
responsible party type: Sponsor