<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT01663402</url>
  </required_header>
  <id_info>
    <org_study_id>EFC11570</org_study_id>
    <secondary_id>2011-005698-21</secondary_id>
    <secondary_id>U1111-1127-4323</secondary_id>
    <nct_id>NCT01663402</nct_id>
  </id_info>
  <brief_title>ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab</brief_title>
  <official_title>A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Sanofi</agency>
      <agency_class>Industry</agency_class>
    </lead_sponsor>
    <collaborator>
      <agency>Regeneron Pharmaceuticals</agency>
      <agency_class>Industry</agency_class>
    </collaborator>
  </sponsors>
  <source>Sanofi</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      Primary Objective:&#xD;
&#xD;
      To compare the effect of alirocumab with placebo on the occurrence of cardiovascular (CV)&#xD;
      events (composite endpoint of coronary heart disease (CHD) death, non-fatal myocardial&#xD;
      infarction (MI), fatal and non-fatal ischemic stroke, unstable angina (UA) requiring&#xD;
      hospitalization) in participants who experienced an acute coronary syndrome (ACS) event 4 to&#xD;
      52 weeks prior to randomization and were treated with evidence-based medical and dietary&#xD;
      management of dyslipidemia.&#xD;
&#xD;
      Secondary Objectives:&#xD;
&#xD;
        -  To evaluate the effect of alirocumab on secondary endpoints (any CHD event , major CHD&#xD;
           event, any CV event, composite of all cause mortality/non-fatal MI/non-fatal ischemic&#xD;
           stroke, CHD deaths, CV deaths, all cause mortality).&#xD;
&#xD;
        -  To evaluate the safety and tolerability of alirocumab.&#xD;
&#xD;
        -  To evaluate the effect of alirocumab on lipid parameters.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      18924 number of participants aged &gt;= 40 years old were randomized in the study.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">October 2012</start_date>
  <completion_date type="Actual">January 23, 2018</completion_date>
  <primary_completion_date type="Actual">January 23, 2018</primary_completion_date>
  <phase>Phase 3</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Prevention</primary_purpose>
    <masking>Double (Participant, Investigator)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>All MACE positively adjudicated by Clinical Events Committee (CEC) in a blinded fashion, were used in the analysis of the composite cardiovascular (CV) outcome measure comprised of Coronary Heart Disease (CHD) death, non-fatal Myocardial Infarction (MI), fatal and non-fatal ischemic stroke (IS), or unstable angina (UA) requiring hospitalization. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of MACE over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>All CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death, non-fatal non-fatal MI, UA requiring hospitalization, or ischemia-driven coronary revascularization procedure. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>All Major CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death and non-fatal MI. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any major CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>All CV events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CV endpoint comprised of any non-fatal CHD event, any CV death and non-fatal IS. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CV event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>All-cause mortality, non-fatal MI and non-fatal IS positively adjudicated by CEC in a blinded fashion, were used in the analysis of this endpoint. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of all-cause mortality, non-fatal MI and non-fatal IS over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CHD death over time. Percentage of observed participants with CHD death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CV death over time. Percentage of observed participants with CV death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the all-cause death over time. Percentage of observed participants with all-cause death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any non-fatal MI over time. Percentage of observed participants with any non-fatal MI (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of fatal or any non-fatal IS over time. Percentage of observed participants with fatal or any non-fatal IS (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any UA requiring hospitalization over time. Percentage of observed participants with any UA requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any ischemia-driven coronary revascularization procedure over time. Percentage of observed participants with any ischemia-driven coronary revascularization procedure (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study</measure>
    <time_frame>From randomization up to 64 months</time_frame>
    <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHF requiring hospitalization over time. Percentage of observed participants with any CHF requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.</description>
  </secondary_outcome>
  <other_outcome>
    <measure>Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis</measure>
    <time_frame>Baseline, Months 4, 12 and 48</time_frame>
    <description>Adjusted means and standard errors at Month 4, 12 and 48 from multiple imputation approach (to account for missing data) followed by analyses of covariance (ANCOVA) model with the fixed categorical effect of treatment group and the continuous fixed covariate of baseline LDL-C value, including all available post-baseline data from Month 1 up to Month 48 regardless of status on- or off-treatment.</description>
  </other_outcome>
  <other_outcome>
    <measure>Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: On-Treatment Analysis</measure>
    <time_frame>Baseline, Months 4, 12 and 48</time_frame>
    <description>Adjusted Least-squares (LS) means and standard errors at Month 4, 12 and 48 were obtained from a mixed-effect model with repeated measures (MMRM) including available post-baseline on-treatment data from Month 1 up to Month 48 (i.e. up to 21 days after last injection).</description>
  </other_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Actual">18924</enrollment>
  <condition>Atherosclerotic Cardiovascular Disease</condition>
  <arm_group>
    <arm_group_label>Placebo</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>Placebo (for alirocumab) subcutaneous (SC) injection every 2 weeks (Q2W) added to stable Lipid-Modifying Therapy (LMT) for up to 64 months.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when Low-Density Lipoprotein Cholesterol (LDL-C) levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
  </arm_group>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Alirocumab</intervention_name>
    <description>Alirocumab administered as SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.</description>
    <arm_group_label>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</arm_group_label>
    <other_name>SAR236553</other_name>
    <other_name>REGN727</other_name>
    <other_name>Praluent®</other_name>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>Placebo</intervention_name>
    <description>Placebo matched to alirocumab administered as a SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.</description>
    <arm_group_label>Placebo</arm_group_label>
  </intervention>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>LMT</intervention_name>
    <description>Statins (atorvastatin or rosuvastatin) at stable maximal tolerated dose of statin with or without other LMT as clinically indicated.</description>
    <arm_group_label>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</arm_group_label>
    <arm_group_label>Placebo</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion criteria :&#xD;
&#xD;
        Recently (&lt; 52 weeks) hospitalized for ACS.&#xD;
&#xD;
        Exclusion criteria:&#xD;
&#xD;
          -  Age &lt; 40 years.&#xD;
&#xD;
          -  ACS event occurring more than 52 weeks prior to randomization visit.&#xD;
&#xD;
          -  LDL-C likely to be &lt;70 mg/dL (&lt;1.81 mmo/L), and apolipoprotein B (ApoB) &lt;80 mg/dL&#xD;
             (&lt;0.8 g/L), and non - high-density lipoprotein cholesterol (HDL-C) &lt;100 mg/dL (&lt;2.59&#xD;
             mmol/L) with evidence-based medical and dietary management of dyslipidemia.&#xD;
&#xD;
        The above information is not intended to contain all considerations relevant to a&#xD;
        participant's potential participation in a clinical trial.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>40 Years</minimum_age>
    <maximum_age>N/A</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Clinical Sciences &amp; Operations</last_name>
    <role>Study Director</role>
    <affiliation>Sanofi</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Investigational Site Number 840163</name>
      <address>
        <city>Birmingham</city>
        <state>Alabama</state>
        <zip>35235</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840060</name>
      <address>
        <city>Birmingham</city>
        <state>Alabama</state>
        <zip>35294</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840117</name>
      <address>
        <city>Huntsville</city>
        <state>Alabama</state>
        <zip>35801</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840192</name>
      <address>
        <city>Huntsville</city>
        <state>Alabama</state>
        <zip>35801</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840121</name>
      <address>
        <city>Mobile</city>
        <state>Alabama</state>
        <zip>36604</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840319</name>
      <address>
        <city>Mobile</city>
        <state>Alabama</state>
        <zip>36695</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840332</name>
      <address>
        <city>Atlantis</city>
        <state>Arizona</state>
        <zip>33462</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840320</name>
      <address>
        <city>Newport Beach</city>
        <state>Arizona</state>
        <zip>92663</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840103</name>
      <address>
        <city>Tucson</city>
        <state>Arizona</state>
        <zip>85724</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840084</name>
      <address>
        <city>Tucson</city>
        <state>Arizona</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840139</name>
      <address>
        <city>Banning</city>
        <state>California</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840286</name>
      <address>
        <city>Beverly Hills</city>
        <state>California</state>
        <zip>90210</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840246</name>
      <address>
        <city>Beverly Hills</city>
        <state>California</state>
        <zip>90211</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840353</name>
      <address>
        <city>Beverly Hills</city>
        <state>California</state>
        <zip>90211</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840341</name>
      <address>
        <city>Carmichael</city>
        <state>California</state>
        <zip>95608</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840299</name>
      <address>
        <city>Chula Vista</city>
        <state>California</state>
        <zip>91910</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840164</name>
      <address>
        <city>Fresno</city>
        <state>California</state>
        <zip>93721</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840076</name>
      <address>
        <city>Fullerton</city>
        <state>California</state>
        <zip>92835</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840073</name>
      <address>
        <city>Huntington Beach</city>
        <state>California</state>
        <zip>92648</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840092</name>
      <address>
        <city>La Jolla</city>
        <state>California</state>
        <zip>92093</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840208</name>
      <address>
        <city>Long Beach</city>
        <state>California</state>
        <zip>90801</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840068</name>
      <address>
        <city>Long Beach</city>
        <state>California</state>
        <zip>90822</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840269</name>
      <address>
        <city>Los Alamitos</city>
        <state>California</state>
        <zip>90720</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840009</name>
      <address>
        <city>Los Angeles</city>
        <state>California</state>
        <zip>90073</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840282</name>
      <address>
        <city>Los Angeles</city>
        <state>California</state>
        <zip>90095</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840019</name>
      <address>
        <city>Mission Viejo</city>
        <state>California</state>
        <zip>92691</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840336</name>
      <address>
        <city>Moreno Valley</city>
        <state>California</state>
        <zip>92553</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840124</name>
      <address>
        <city>Northridge</city>
        <state>California</state>
        <zip>91325</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840251</name>
      <address>
        <city>Pasadena</city>
        <state>California</state>
        <zip>91105</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840289</name>
      <address>
        <city>Pasadena</city>
        <state>California</state>
        <zip>91105</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840312</name>
      <address>
        <city>Port Hueneme</city>
        <state>California</state>
        <zip>93041</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840261</name>
      <address>
        <city>San Diego</city>
        <state>California</state>
        <zip>92120</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840310</name>
      <address>
        <city>San Diego</city>
        <state>California</state>
        <zip>92120</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840024</name>
      <address>
        <city>San Diego</city>
        <state>California</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840071</name>
      <address>
        <city>Santa Ana</city>
        <state>California</state>
        <zip>92704</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840236</name>
      <address>
        <city>Santa Rosa</city>
        <state>California</state>
        <zip>95405</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840012</name>
      <address>
        <city>Torrance</city>
        <state>California</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840096</name>
      <address>
        <city>Aurora</city>
        <state>Colorado</state>
        <zip>80012</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840037</name>
      <address>
        <city>Colorado Springs</city>
        <state>Colorado</state>
        <zip>80909</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840189</name>
      <address>
        <city>Denver</city>
        <state>Colorado</state>
        <zip>80220</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840122</name>
      <address>
        <city>Bridgeport</city>
        <state>Connecticut</state>
        <zip>06606</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840219</name>
      <address>
        <city>Guilford</city>
        <state>Connecticut</state>
        <zip>06437</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840347</name>
      <address>
        <city>Altamonte Springs</city>
        <state>Florida</state>
        <zip>32714</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840066</name>
      <address>
        <city>Clearwater</city>
        <state>Florida</state>
        <zip>33756</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840079</name>
      <address>
        <city>Daytona Beach</city>
        <state>Florida</state>
        <zip>32114</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840051</name>
      <address>
        <city>Daytona Beach</city>
        <state>Florida</state>
        <zip>32117</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840368</name>
      <address>
        <city>Delray Beach</city>
        <state>Florida</state>
        <zip>33484</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840242</name>
      <address>
        <city>Fort Lauderdale</city>
        <state>Florida</state>
        <zip>33308</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840134</name>
      <address>
        <city>Gainesville</city>
        <state>Florida</state>
        <zip>32608</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840327</name>
      <address>
        <city>Hollywood</city>
        <state>Florida</state>
        <zip>33021</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840153</name>
      <address>
        <city>Hudson</city>
        <state>Florida</state>
        <zip>34667</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840105</name>
      <address>
        <city>Hudson</city>
        <state>Florida</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840253</name>
      <address>
        <city>Jacksonville</city>
        <state>Florida</state>
        <zip>32204</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840141</name>
      <address>
        <city>Jacksonville</city>
        <state>Florida</state>
        <zip>32209</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840042</name>
      <address>
        <city>Jacksonville</city>
        <state>Florida</state>
        <zip>32216</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840206</name>
      <address>
        <city>Jacksonville</city>
        <state>Florida</state>
        <zip>32216</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840063</name>
      <address>
        <city>Jacksonville</city>
        <state>Florida</state>
        <zip>32258</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840002</name>
      <address>
        <city>Jupiter</city>
        <state>Florida</state>
        <zip>33458</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840119</name>
      <address>
        <city>Largo</city>
        <state>Florida</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840241</name>
      <address>
        <city>Miami Beach</city>
        <state>Florida</state>
        <zip>33140</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840210</name>
      <address>
        <city>Mount Clemens</city>
        <state>Florida</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840366</name>
      <address>
        <city>New Port Richey</city>
        <state>Florida</state>
        <zip>34653</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840311</name>
      <address>
        <city>Palm Beach Gardens</city>
        <state>Florida</state>
        <zip>33410</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840280</name>
      <address>
        <city>Palm Harbor</city>
        <state>Florida</state>
        <zip>34684</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840054</name>
      <address>
        <city>Panama City</city>
        <state>Florida</state>
        <zip>32401</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840239</name>
      <address>
        <city>Pembroke Pines</city>
        <state>Florida</state>
        <zip>33024</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840044</name>
      <address>
        <city>Pensacola</city>
        <state>Florida</state>
        <zip>32501</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840367</name>
      <address>
        <city>Plantation</city>
        <state>Florida</state>
        <zip>33317</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840132</name>
      <address>
        <city>Safety Harbor</city>
        <state>Florida</state>
        <zip>34695</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840061</name>
      <address>
        <city>Safety Harbor</city>
        <state>Florida</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840247</name>
      <address>
        <city>Sarasota</city>
        <state>Florida</state>
        <zip>34239</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840264</name>
      <address>
        <city>Tampa</city>
        <state>Florida</state>
        <zip>33606</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840082</name>
      <address>
        <city>Tampa</city>
        <state>Florida</state>
        <zip>33613</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840213</name>
      <address>
        <city>Trinity</city>
        <state>Florida</state>
        <zip>34655</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840165</name>
      <address>
        <city>Wellington</city>
        <state>Florida</state>
        <zip>33449</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840323</name>
      <address>
        <city>West Palm Beach</city>
        <state>Florida</state>
        <zip>33401</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840075</name>
      <address>
        <city>Atlanta</city>
        <state>Georgia</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840176</name>
      <address>
        <city>Augusta</city>
        <state>Georgia</state>
        <zip>30901</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840048</name>
      <address>
        <city>Covington</city>
        <state>Georgia</state>
        <zip>30014</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840065</name>
      <address>
        <city>Cumming</city>
        <state>Georgia</state>
        <zip>30041</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840356</name>
      <address>
        <city>Thomasville</city>
        <state>Georgia</state>
        <zip>31792</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840114</name>
      <address>
        <city>Tucker</city>
        <state>Georgia</state>
        <zip>30084</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840211</name>
      <address>
        <city>Idaho Falls</city>
        <state>Idaho</state>
        <zip>83404</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840237</name>
      <address>
        <city>Arlington Heights</city>
        <state>Illinois</state>
        <zip>60005</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840292</name>
      <address>
        <city>Chicago</city>
        <state>Illinois</state>
        <zip>60612</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840146</name>
      <address>
        <city>Harvey</city>
        <state>Illinois</state>
        <zip>60426</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840340</name>
      <address>
        <city>Joliet</city>
        <state>Illinois</state>
        <zip>60435</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840196</name>
      <address>
        <city>Peoria</city>
        <state>Illinois</state>
        <zip>61614</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840081</name>
      <address>
        <city>Rock Island</city>
        <state>Illinois</state>
        <zip>61201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840090</name>
      <address>
        <city>Rock Island</city>
        <state>Illinois</state>
        <zip>61201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840358</name>
      <address>
        <city>Elkhart</city>
        <state>Indiana</state>
        <zip>46514</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840036</name>
      <address>
        <city>Hammond</city>
        <state>Indiana</state>
        <zip>46320</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840026</name>
      <address>
        <city>Indianapolis</city>
        <state>Indiana</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840102</name>
      <address>
        <city>Muncie</city>
        <state>Indiana</state>
        <zip>47303-3400</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840145</name>
      <address>
        <city>South Bend</city>
        <state>Indiana</state>
        <zip>46601-1075</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840154</name>
      <address>
        <city>Ames</city>
        <state>Iowa</state>
        <zip>50010</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840345</name>
      <address>
        <city>Iowa City</city>
        <state>Iowa</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840283</name>
      <address>
        <city>West Des Moines</city>
        <state>Iowa</state>
        <zip>50266</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840335</name>
      <address>
        <city>Kansas City</city>
        <state>Kansas</state>
        <zip>64116</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840089</name>
      <address>
        <city>Kansas City</city>
        <state>Kansas</state>
        <zip>66160-7321</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840218</name>
      <address>
        <city>Kansas City</city>
        <state>Kansas</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840140</name>
      <address>
        <city>Overland Park</city>
        <state>Kansas</state>
        <zip>66209</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840030</name>
      <address>
        <city>Lexington</city>
        <state>Kentucky</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840023</name>
      <address>
        <city>Louisville</city>
        <state>Kentucky</state>
        <zip>40205</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840007</name>
      <address>
        <city>Louisville</city>
        <state>Kentucky</state>
        <zip>40207</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840279</name>
      <address>
        <city>Owensboro</city>
        <state>Kentucky</state>
        <zip>42303</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840308</name>
      <address>
        <city>Pikeville</city>
        <state>Kentucky</state>
        <zip>41501</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840181</name>
      <address>
        <city>Saint Paul</city>
        <state>Kentucky</state>
        <zip>55102</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840254</name>
      <address>
        <city>Alexandria</city>
        <state>Louisiana</state>
        <zip>71301</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840344</name>
      <address>
        <city>Lafayette</city>
        <state>Louisiana</state>
        <zip>70503</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840187</name>
      <address>
        <city>Lake Charles</city>
        <state>Louisiana</state>
        <zip>70601</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840291</name>
      <address>
        <city>Minden</city>
        <state>Louisiana</state>
        <zip>71055</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840278</name>
      <address>
        <city>New Orleans</city>
        <state>Louisiana</state>
        <zip>70112</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840290</name>
      <address>
        <city>Shreveport</city>
        <state>Louisiana</state>
        <zip>71103</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840142</name>
      <address>
        <city>Auburn</city>
        <state>Maine</state>
        <zip>04210</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840148</name>
      <address>
        <city>Auburn</city>
        <state>Maine</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840097</name>
      <address>
        <city>Bangor</city>
        <state>Maine</state>
        <zip>04401</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840234</name>
      <address>
        <city>Framingham</city>
        <state>Maine</state>
        <zip>01702</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840276</name>
      <address>
        <city>Scarborough</city>
        <state>Maine</state>
        <zip>04074</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840351</name>
      <address>
        <city>Annapolis</city>
        <state>Maryland</state>
        <zip>21401</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840072</name>
      <address>
        <city>Beltsville</city>
        <state>Maryland</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840193</name>
      <address>
        <city>Bethesda</city>
        <state>Maryland</state>
        <zip>20817</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840200</name>
      <address>
        <city>Columbia</city>
        <state>Maryland</state>
        <zip>21044</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840349</name>
      <address>
        <city>Rockville</city>
        <state>Maryland</state>
        <zip>20850</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840111</name>
      <address>
        <city>Winfield</city>
        <state>Maryland</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840056</name>
      <address>
        <city>Boston</city>
        <state>Massachusetts</state>
        <zip>02111</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840144</name>
      <address>
        <city>Flint</city>
        <state>Michigan</state>
        <zip>48532</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840365</name>
      <address>
        <city>Grandville</city>
        <state>Michigan</state>
        <zip>49418</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840093</name>
      <address>
        <city>Kalamazoo</city>
        <state>Michigan</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840198</name>
      <address>
        <city>Lansing</city>
        <state>Michigan</state>
        <zip>48910</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840087</name>
      <address>
        <city>Rochester Hills</city>
        <state>Michigan</state>
        <zip>48085</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840004</name>
      <address>
        <city>Springfield</city>
        <state>Michigan</state>
        <zip>65807</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840267</name>
      <address>
        <city>Springfield</city>
        <state>Michigan</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840035</name>
      <address>
        <city>Ypsilanti</city>
        <state>Michigan</state>
        <zip>48197</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840199</name>
      <address>
        <city>Duluth</city>
        <state>Minnesota</state>
        <zip>55805</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840116</name>
      <address>
        <city>Edina</city>
        <state>Minnesota</state>
        <zip>55435</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840281</name>
      <address>
        <city>Minneapolis</city>
        <state>Minnesota</state>
        <zip>55407</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840094</name>
      <address>
        <city>Saint Cloud</city>
        <state>Minnesota</state>
        <zip>56303</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840324</name>
      <address>
        <city>Saint Paul</city>
        <state>Minnesota</state>
        <zip>55101</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840046</name>
      <address>
        <city>Columbia</city>
        <state>Missouri</state>
        <zip>65201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840180</name>
      <address>
        <city>Independence</city>
        <state>Missouri</state>
        <zip>64057</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840274</name>
      <address>
        <city>Little Rock</city>
        <state>Missouri</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840013</name>
      <address>
        <city>Marquette</city>
        <state>Missouri</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840179</name>
      <address>
        <city>Overland</city>
        <state>Missouri</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840228</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <zip>63128</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840233</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <zip>63128</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840235</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <zip>63128</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840175</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <zip>63136</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840125</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <zip>63141</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840168</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840032</name>
      <address>
        <city>Kalispell</city>
        <state>Montana</state>
        <zip>59901</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840033</name>
      <address>
        <city>Grand Island</city>
        <state>Nebraska</state>
        <zip>68803</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840015</name>
      <address>
        <city>Omaha</city>
        <state>Nebraska</state>
        <zip>68122</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840021</name>
      <address>
        <city>Omaha</city>
        <state>Nebraska</state>
        <zip>68122</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840001</name>
      <address>
        <city>Omaha</city>
        <state>Nebraska</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840221</name>
      <address>
        <city>Las Vegas</city>
        <state>Nevada</state>
        <zip>89146</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840062</name>
      <address>
        <city>Nashua</city>
        <state>New Hampshire</state>
        <zip>03060</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840077</name>
      <address>
        <city>Bridgewater</city>
        <state>New Jersey</state>
        <zip>08807</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840173</name>
      <address>
        <city>Bridgewater</city>
        <state>New Jersey</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840127</name>
      <address>
        <city>Flemington</city>
        <state>New Jersey</state>
        <zip>08822</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840359</name>
      <address>
        <city>Hackensack</city>
        <state>New Jersey</state>
        <zip>07601</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840348</name>
      <address>
        <city>Moorestown</city>
        <state>New Jersey</state>
        <zip>08057</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840128</name>
      <address>
        <city>New Brunswick</city>
        <state>New Jersey</state>
        <zip>08903-0019</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840167</name>
      <address>
        <city>Pomona</city>
        <state>New Jersey</state>
        <zip>08240</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840067</name>
      <address>
        <city>Ridgewood</city>
        <state>New Jersey</state>
        <zip>07506</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840250</name>
      <address>
        <city>Somerset</city>
        <state>New Jersey</state>
        <zip>08873</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840277</name>
      <address>
        <city>Voorhees</city>
        <state>New Jersey</state>
        <zip>08043</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840083</name>
      <address>
        <city>Westwood</city>
        <state>New Jersey</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840222</name>
      <address>
        <city>Bronx</city>
        <state>New York</state>
        <zip>10467</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840322</name>
      <address>
        <city>Buffalo</city>
        <state>New York</state>
        <zip>14215</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840248</name>
      <address>
        <city>New York</city>
        <state>New York</state>
        <zip>10016</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840371</name>
      <address>
        <city>New York</city>
        <state>New York</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840333</name>
      <address>
        <city>Newburgh</city>
        <state>New York</state>
        <zip>47630</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840017</name>
      <address>
        <city>Poughkeepsie</city>
        <state>New York</state>
        <zip>12601</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840166</name>
      <address>
        <city>Valhalla</city>
        <state>New York</state>
        <zip>10595</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840354</name>
      <address>
        <city>Williamsville</city>
        <state>New York</state>
        <zip>14221</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840070</name>
      <address>
        <city>Elizabeth City</city>
        <state>North Carolina</state>
        <zip>27909</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840303</name>
      <address>
        <city>Greenville</city>
        <state>North Carolina</state>
        <zip>27834</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840182</name>
      <address>
        <city>Greenville</city>
        <state>North Carolina</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840243</name>
      <address>
        <city>Raleigh</city>
        <state>North Carolina</state>
        <zip>27610</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840342</name>
      <address>
        <city>Raleigh</city>
        <state>North Carolina</state>
        <zip>27610</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840293</name>
      <address>
        <city>Rocky Mount</city>
        <state>North Carolina</state>
        <zip>27804</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840088</name>
      <address>
        <city>Statesville</city>
        <state>North Carolina</state>
        <zip>28627</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840052</name>
      <address>
        <city>Wilmington</city>
        <state>North Carolina</state>
        <zip>28401</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840306</name>
      <address>
        <city>Baltimore</city>
        <state>North Dakota</state>
        <zip>21229</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840214</name>
      <address>
        <city>Fargo</city>
        <state>North Dakota</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840095</name>
      <address>
        <city>Minot</city>
        <state>North Dakota</state>
        <zip>58701</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840257</name>
      <address>
        <city>Mountain Lakes</city>
        <state>North Dakota</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840364</name>
      <address>
        <city>Akron</city>
        <state>Ohio</state>
        <zip>44304</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840131</name>
      <address>
        <city>Cincinnati</city>
        <state>Ohio</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840045</name>
      <address>
        <city>Columbus</city>
        <state>Ohio</state>
        <zip>43210</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840265</name>
      <address>
        <city>Columbus</city>
        <state>Ohio</state>
        <zip>43210</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840113</name>
      <address>
        <city>Lorain</city>
        <state>Ohio</state>
        <zip>44053</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840115</name>
      <address>
        <city>Lorain</city>
        <state>Ohio</state>
        <zip>44053</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840309</name>
      <address>
        <city>Maumee</city>
        <state>Ohio</state>
        <zip>43537</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840297</name>
      <address>
        <city>Springfield</city>
        <state>Ohio</state>
        <zip>45505</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840172</name>
      <address>
        <city>Toledo</city>
        <state>Ohio</state>
        <zip>43623</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840263</name>
      <address>
        <city>Youngstown</city>
        <state>Ohio</state>
        <zip>44501</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840334</name>
      <address>
        <city>Oklahoma City</city>
        <state>Oklahoma</state>
        <zip>73104</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840337</name>
      <address>
        <city>Oklahoma City</city>
        <state>Oklahoma</state>
        <zip>73120</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840018</name>
      <address>
        <city>Tulsa</city>
        <state>Oklahoma</state>
        <zip>74104</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840184</name>
      <address>
        <city>Portland</city>
        <state>Oregon</state>
        <zip>97239</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840133</name>
      <address>
        <city>Allentown</city>
        <state>Pennsylvania</state>
        <zip>18102</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840104</name>
      <address>
        <city>Beaver</city>
        <state>Pennsylvania</state>
        <zip>15009</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840170</name>
      <address>
        <city>Camp Hill</city>
        <state>Pennsylvania</state>
        <zip>17011</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840020</name>
      <address>
        <city>Doylestown</city>
        <state>Pennsylvania</state>
        <zip>18901</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840016</name>
      <address>
        <city>Erie</city>
        <state>Pennsylvania</state>
        <zip>16502-4604</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840329</name>
      <address>
        <city>Goodyear</city>
        <state>Pennsylvania</state>
        <zip>85395</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840126</name>
      <address>
        <city>Knoxville</city>
        <state>Pennsylvania</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840249</name>
      <address>
        <city>Lancaster</city>
        <state>Pennsylvania</state>
        <zip>17603</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840150</name>
      <address>
        <city>Lancaster</city>
        <state>Pennsylvania</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840231</name>
      <address>
        <city>Philadelphia</city>
        <state>Pennsylvania</state>
        <zip>19085</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840339</name>
      <address>
        <city>Philadelphia</city>
        <state>Pennsylvania</state>
        <zip>19104</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840230</name>
      <address>
        <city>Pittsburgh</city>
        <state>Pennsylvania</state>
        <zip>15240</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840028</name>
      <address>
        <city>Sayre</city>
        <state>Pennsylvania</state>
        <zip>18840</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840069</name>
      <address>
        <city>Scranton</city>
        <state>Pennsylvania</state>
        <zip>18503</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840316</name>
      <address>
        <city>Scranton</city>
        <state>Pennsylvania</state>
        <zip>18510</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840273</name>
      <address>
        <city>Seven Fields</city>
        <state>Pennsylvania</state>
        <zip>16046</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840227</name>
      <address>
        <city>Washington</city>
        <state>Pennsylvania</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840129</name>
      <address>
        <city>Pawtucket</city>
        <state>Rhode Island</state>
        <zip>02860</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840118</name>
      <address>
        <city>Anderson</city>
        <state>South Carolina</state>
        <zip>29621</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840190</name>
      <address>
        <city>Greenwood</city>
        <state>South Carolina</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840360</name>
      <address>
        <city>Lancaster</city>
        <state>South Carolina</state>
        <zip>29720</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840314</name>
      <address>
        <city>Myrtle Beach</city>
        <state>South Carolina</state>
        <zip>29572</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840008</name>
      <address>
        <city>Rapid City</city>
        <state>South Dakota</state>
        <zip>57701</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840285</name>
      <address>
        <city>Chattanooga</city>
        <state>Tennessee</state>
        <zip>37421</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840287</name>
      <address>
        <city>Jackson</city>
        <state>Tennessee</state>
        <zip>38301</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840040</name>
      <address>
        <city>Johnson City</city>
        <state>Tennessee</state>
        <zip>37604</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840238</name>
      <address>
        <city>Knoxville</city>
        <state>Tennessee</state>
        <zip>37917-4524</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840195</name>
      <address>
        <city>Oak Ridge</city>
        <state>Tennessee</state>
        <zip>37830</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840205</name>
      <address>
        <city>Amarillo</city>
        <state>Texas</state>
        <zip>79106</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840352</name>
      <address>
        <city>Amarillo</city>
        <state>Texas</state>
        <zip>79106</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840135</name>
      <address>
        <city>Austin</city>
        <state>Texas</state>
        <zip>78756</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840301</name>
      <address>
        <city>Dallas</city>
        <state>Texas</state>
        <zip>75226</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840152</name>
      <address>
        <city>Dallas</city>
        <state>Texas</state>
        <zip>75231</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840157</name>
      <address>
        <city>Dallas</city>
        <state>Texas</state>
        <zip>75390</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840229</name>
      <address>
        <city>Fort Worth</city>
        <state>Texas</state>
        <zip>76104</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840120</name>
      <address>
        <city>Fort Worth</city>
        <state>Texas</state>
        <zip>76107</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840258</name>
      <address>
        <city>Fort Worth</city>
        <state>Texas</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840136</name>
      <address>
        <city>Kingwood</city>
        <state>Texas</state>
        <zip>77339</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840027</name>
      <address>
        <city>Lubbock</city>
        <state>Texas</state>
        <zip>79410</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840202</name>
      <address>
        <city>Lufkin</city>
        <state>Texas</state>
        <zip>75904</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840270</name>
      <address>
        <city>Odessa</city>
        <state>Texas</state>
        <zip>79761</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840162</name>
      <address>
        <city>San Antonio</city>
        <state>Texas</state>
        <zip>78229</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840232</name>
      <address>
        <city>San Antonio</city>
        <state>Texas</state>
        <zip>78229</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840328</name>
      <address>
        <city>Schertz</city>
        <state>Texas</state>
        <zip>78154</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840158</name>
      <address>
        <city>Tyler</city>
        <state>Texas</state>
        <zip>75701</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840318</name>
      <address>
        <city>Victoria</city>
        <state>Texas</state>
        <zip>77901</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840245</name>
      <address>
        <city>Wichita Falls</city>
        <state>Texas</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840256</name>
      <address>
        <city>Orem</city>
        <state>Utah</state>
        <zip>84058</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840296</name>
      <address>
        <city>Salt Lake City</city>
        <state>Utah</state>
        <zip>84124</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840053</name>
      <address>
        <city>Burlington</city>
        <state>Vermont</state>
        <zip>05401</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840049</name>
      <address>
        <city>Charlottesville</city>
        <state>Virginia</state>
        <zip>22908-0679</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840260</name>
      <address>
        <city>Charlottesville</city>
        <state>Virginia</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840350</name>
      <address>
        <city>Harrisonburg</city>
        <state>Virginia</state>
        <zip>22801</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840215</name>
      <address>
        <city>Leesburg</city>
        <state>Virginia</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840010</name>
      <address>
        <city>Lynchburg</city>
        <state>Virginia</state>
        <zip>24501</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840225</name>
      <address>
        <city>Manassas</city>
        <state>Virginia</state>
        <zip>20109</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840022</name>
      <address>
        <city>Richmond</city>
        <state>Virginia</state>
        <zip>23225</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840078</name>
      <address>
        <city>Richmond</city>
        <state>Virginia</state>
        <zip>23249</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840110</name>
      <address>
        <city>Richmond</city>
        <state>Virginia</state>
        <zip>23298</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840149</name>
      <address>
        <city>Roanoke</city>
        <state>Virginia</state>
        <zip>24014</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840223</name>
      <address>
        <city>Winchester</city>
        <state>Virginia</state>
        <zip>22601</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840025</name>
      <address>
        <city>Bellevue</city>
        <state>Washington</state>
        <zip>98004</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840321</name>
      <address>
        <city>Everett</city>
        <state>Washington</state>
        <zip>98201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840326</name>
      <address>
        <city>Spokane</city>
        <state>Washington</state>
        <zip>99204</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840086</name>
      <address>
        <city>Tacoma</city>
        <state>Washington</state>
        <zip>98415-0299</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840295</name>
      <address>
        <city>Walla Walla</city>
        <state>Washington</state>
        <zip>99362</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840262</name>
      <address>
        <city>Burlington</city>
        <state>Wisconsin</state>
        <zip>53105</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840298</name>
      <address>
        <city>Green Bay</city>
        <state>Wisconsin</state>
        <zip>54303</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840059</name>
      <address>
        <city>Green Bay</city>
        <state>Wisconsin</state>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840177</name>
      <address>
        <city>La Crosse</city>
        <state>Wisconsin</state>
        <zip>54601</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 840300</name>
      <address>
        <city>Manitowoc</city>
        <state>Wisconsin</state>
        <zip>54220</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032012</name>
      <address>
        <city>Adrogue</city>
        <zip>B1846DSK</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032018</name>
      <address>
        <city>Bahia Blanca</city>
        <zip>B8000AKK</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032050</name>
      <address>
        <city>Caba</city>
        <zip>C1093AAS</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032048</name>
      <address>
        <city>Caba</city>
        <zip>C1118AAE</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032023</name>
      <address>
        <city>Caba</city>
        <zip>C1119ACN</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032020</name>
      <address>
        <city>Caba</city>
        <zip>C1180AAX</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032041</name>
      <address>
        <city>Caba</city>
        <zip>C1181ACH</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032011</name>
      <address>
        <city>Caba</city>
        <zip>C1425AGC</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032045</name>
      <address>
        <city>Caba</city>
        <zip>C1426EGR</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032010</name>
      <address>
        <city>Ciudad De Buenos Aires</city>
        <zip>C1428DCO</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032046</name>
      <address>
        <city>Ciudadela</city>
        <zip>B1702BML</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032032</name>
      <address>
        <city>Cordoba</city>
        <zip>X5000AAW</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032019</name>
      <address>
        <city>Cordoba</city>
        <zip>X5000AAX</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032021</name>
      <address>
        <city>Cordoba</city>
        <zip>X5000EPU</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032008</name>
      <address>
        <city>Cordoba</city>
        <zip>X5002AOQ</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032042</name>
      <address>
        <city>Cordoba</city>
        <zip>X5004BAL</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032038</name>
      <address>
        <city>Cordoba</city>
        <zip>X5006IKK</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032031</name>
      <address>
        <city>Cordoba</city>
        <zip>X5016KEH</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032017</name>
      <address>
        <city>Coronel Suarez</city>
        <zip>B7540GHD</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032009</name>
      <address>
        <city>Corrientes</city>
        <zip>W3400AMZ</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032026</name>
      <address>
        <city>Córdoba</city>
        <zip>X5000JHQ</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032049</name>
      <address>
        <city>Córdoba</city>
        <zip>X5003DCE</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032005</name>
      <address>
        <city>Junin</city>
        <zip>B6000BHA</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032001</name>
      <address>
        <city>La Plata</city>
        <zip>B1900AXI</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032040</name>
      <address>
        <city>La Plata</city>
        <zip>B1906ESC</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032033</name>
      <address>
        <city>Mar Del Plata</city>
        <zip>B7600FYK</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032014</name>
      <address>
        <city>Mar Del Plata</city>
        <zip>B7600FZN</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032016</name>
      <address>
        <city>Mendoza</city>
        <zip>5500</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032030</name>
      <address>
        <city>Merlo</city>
        <zip>B1722COV</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032036</name>
      <address>
        <city>Moron</city>
        <zip>B1708CGU</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032007</name>
      <address>
        <city>Olivos</city>
        <zip>1638</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032044</name>
      <address>
        <city>Olivos</city>
        <zip>B1605DSX</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032004</name>
      <address>
        <city>Quilmes</city>
        <zip>B1878DKF</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032025</name>
      <address>
        <city>Rafaela</city>
        <zip>S2300MMA</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032035</name>
      <address>
        <city>Ramos Mejia</city>
        <zip>B1704ETD</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032039</name>
      <address>
        <city>Resistencia</city>
        <zip>H3500CDM</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032028</name>
      <address>
        <city>Rosario</city>
        <zip>S2000DEJ</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032024</name>
      <address>
        <city>Rosario</city>
        <zip>S2000DSR</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032053</name>
      <address>
        <city>Salta</city>
        <zip>4400</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032037</name>
      <address>
        <city>San Isidro</city>
        <zip>B1642DCB</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032052</name>
      <address>
        <city>San Martin</city>
        <zip>B1650NBN</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032013</name>
      <address>
        <city>San Martin</city>
        <zip>B1685CSQ</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032002</name>
      <address>
        <city>San Miguel De Tucuman</city>
        <zip>T4000ICL</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032034</name>
      <address>
        <city>San Miguel De Tucuman</city>
        <zip>T4000IFL</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032006</name>
      <address>
        <city>San Nicolas</city>
        <zip>B2900DMH</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032043</name>
      <address>
        <city>Santa Fe</city>
        <zip>S3000EOZ</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032003</name>
      <address>
        <city>Santa Fe</city>
        <zip>S3000FWO</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032051</name>
      <address>
        <city>Santa Rosa</city>
        <zip>L6300DSD</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032047</name>
      <address>
        <city>Santiago Del Estero</city>
        <zip>G4200AQK</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032029</name>
      <address>
        <city>Venado Tuerto</city>
        <zip>S2600KUE</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032022</name>
      <address>
        <city>Villa Maria</city>
        <zip>X5900JKA</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 032015</name>
      <address>
        <city>Zarate</city>
        <zip>B2800DGH</zip>
        <country>Argentina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036002</name>
      <address>
        <city>Ashford</city>
        <zip>5035</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036023</name>
      <address>
        <city>Auchenflower</city>
        <zip>4066</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036024</name>
      <address>
        <city>Ballarat</city>
        <zip>3353</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036020</name>
      <address>
        <city>Bedford Park</city>
        <zip>5042</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036015</name>
      <address>
        <city>Bruce</city>
        <zip>2617</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036026</name>
      <address>
        <city>Cairns</city>
        <zip>4870</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036005</name>
      <address>
        <city>Chermside</city>
        <zip>4032</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036008</name>
      <address>
        <city>Chermside</city>
        <zip>4032</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036011</name>
      <address>
        <city>Coffs Harbour</city>
        <zip>2450</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036003</name>
      <address>
        <city>Concord</city>
        <zip>2137</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036017</name>
      <address>
        <city>Elizabeth Vale</city>
        <zip>5112</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036006</name>
      <address>
        <city>Fullarton</city>
        <zip>5063</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036004</name>
      <address>
        <city>Gosford</city>
        <zip>2250</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036019</name>
      <address>
        <city>Heidelberg West</city>
        <zip>3081</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036027</name>
      <address>
        <city>Hobart</city>
        <zip>7001</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036009</name>
      <address>
        <city>Kogarah</city>
        <zip>2217</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036012</name>
      <address>
        <city>Mildura</city>
        <zip>3500</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036028</name>
      <address>
        <city>Nambour</city>
        <zip>4560</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036013</name>
      <address>
        <city>New Lambton</city>
        <zip>2305</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036010</name>
      <address>
        <city>Perth</city>
        <zip>6000</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036014</name>
      <address>
        <city>Prahran</city>
        <zip>3004</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036018</name>
      <address>
        <city>Redcliffe</city>
        <zip>4020</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036022</name>
      <address>
        <city>Richmond</city>
        <zip>3121</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036025</name>
      <address>
        <city>Woodville South</city>
        <zip>5011</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 036021</name>
      <address>
        <city>Woolloongabba</city>
        <zip>4102</zip>
        <country>Australia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 040004</name>
      <address>
        <city>Feldkirch</city>
        <zip>6800</zip>
        <country>Austria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 040007</name>
      <address>
        <city>Graz</city>
        <zip>8036</zip>
        <country>Austria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 040001</name>
      <address>
        <city>Salzburg</city>
        <zip>5020</zip>
        <country>Austria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 040006</name>
      <address>
        <city>Wien</city>
        <zip>1030</zip>
        <country>Austria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 040003</name>
      <address>
        <city>Wien</city>
        <zip>1090</zip>
        <country>Austria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 040002</name>
      <address>
        <city>Wien</city>
        <zip>1160</zip>
        <country>Austria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056016</name>
      <address>
        <city>Aalst</city>
        <zip>9300</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056003</name>
      <address>
        <city>Antwerpen</city>
        <zip>2060</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056002</name>
      <address>
        <city>Antwerpen</city>
        <zip>B-2020</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056008</name>
      <address>
        <city>Bonheiden</city>
        <zip>2820</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056014</name>
      <address>
        <city>Brasschaat</city>
        <zip>2930</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056021</name>
      <address>
        <city>Brussels</city>
        <zip>1070</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056005</name>
      <address>
        <city>Bruxelles</city>
        <zip>1000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056004</name>
      <address>
        <city>Bruxelles</city>
        <zip>1200</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056017</name>
      <address>
        <city>Edegem</city>
        <zip>B-2650</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056024</name>
      <address>
        <city>Genk</city>
        <zip>3600</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056007</name>
      <address>
        <city>Gent</city>
        <zip>9000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056018</name>
      <address>
        <city>Gent</city>
        <zip>9000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056020</name>
      <address>
        <city>La Louviere</city>
        <zip>7100</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056009</name>
      <address>
        <city>Leuven</city>
        <zip>3000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056015</name>
      <address>
        <city>Liège</city>
        <zip>4000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056010</name>
      <address>
        <city>Mechelen</city>
        <zip>2800</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056013</name>
      <address>
        <city>Mol</city>
        <zip>2400</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056001</name>
      <address>
        <city>Ottignies</city>
        <zip>1340</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056012</name>
      <address>
        <city>Overpelt</city>
        <zip>3900</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056006</name>
      <address>
        <city>Roeselare</city>
        <zip>8800</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 056019</name>
      <address>
        <city>Tienen</city>
        <zip>3300</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070001</name>
      <address>
        <city>Banja Luka</city>
        <zip>78000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070002</name>
      <address>
        <city>Banja Luka</city>
        <zip>78000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070011</name>
      <address>
        <city>Bihac</city>
        <zip>77000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070003</name>
      <address>
        <city>Mostar</city>
        <zip>8000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070004</name>
      <address>
        <city>Mostar</city>
        <zip>8000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070005</name>
      <address>
        <city>Sarajevo</city>
        <zip>71000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070007</name>
      <address>
        <city>Sarajevo</city>
        <zip>71000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070010</name>
      <address>
        <city>Sarajevo</city>
        <zip>71000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070008</name>
      <address>
        <city>Tuzla</city>
        <zip>75000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070009</name>
      <address>
        <city>Tuzla</city>
        <zip>75000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 070006</name>
      <address>
        <city>Zenica</city>
        <zip>72000</zip>
        <country>Bosnia and Herzegovina</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076029</name>
      <address>
        <city>Aparecida De Goiania</city>
        <zip>74905-410</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076032</name>
      <address>
        <city>Belem</city>
        <zip>66087-660</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076017</name>
      <address>
        <city>Belo Horizonte</city>
        <zip>30140-062</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076004</name>
      <address>
        <city>Belo Horizonte</city>
        <zip>30150-221</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076022</name>
      <address>
        <city>Belo Horizonte</city>
        <zip>30150-320</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076038</name>
      <address>
        <city>Belo Horizonte</city>
        <zip>31110-580</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076002</name>
      <address>
        <city>Blumenau</city>
        <zip>89010906</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076011</name>
      <address>
        <city>Brasilia</city>
        <zip>70390-903</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076007</name>
      <address>
        <city>Brasilia</city>
        <zip>70710-100</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076003</name>
      <address>
        <city>Campina Grande Do Sul</city>
        <zip>83430-000</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076006</name>
      <address>
        <city>Campinas</city>
        <zip>13015-001</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076040</name>
      <address>
        <city>Canoas</city>
        <zip>92200-000</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076033</name>
      <address>
        <city>Curitiba</city>
        <zip>80430-100</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076005</name>
      <address>
        <city>Curitiba</city>
        <zip>80730-150</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076009</name>
      <address>
        <city>Fortaleza</city>
        <zip>60110-110</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076008</name>
      <address>
        <city>Fortaleza</city>
        <zip>60170-320</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076012</name>
      <address>
        <city>Goiania</city>
        <zip>74223-130</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076021</name>
      <address>
        <city>Goiania</city>
        <zip>74605-020</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076019</name>
      <address>
        <city>Passo Fundo</city>
        <zip>99010-180</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076018</name>
      <address>
        <city>Pelotas</city>
        <zip>96015290</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076024</name>
      <address>
        <city>Porto Alegre</city>
        <zip>90020-090</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076026</name>
      <address>
        <city>Porto Alegre</city>
        <zip>90110270</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076014</name>
      <address>
        <city>Porto Alegre</city>
        <zip>90610-000</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076001</name>
      <address>
        <city>Porto Alegre</city>
        <zip>90620-001</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076027</name>
      <address>
        <city>Porto Alegre</city>
        <zip>91350-250</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076035</name>
      <address>
        <city>Riberao Preto</city>
        <zip>14048-900</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076010</name>
      <address>
        <city>Rio De Janeiro</city>
        <zip>22271-100</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076015</name>
      <address>
        <city>Salvador</city>
        <zip>40050-410</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076041</name>
      <address>
        <city>Salvador</city>
        <zip>40050-410</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076036</name>
      <address>
        <city>Santo Andre</city>
        <zip>18270170</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076031</name>
      <address>
        <city>Sao Bernardo Do Campo</city>
        <zip>9780000</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076030</name>
      <address>
        <city>Sao Jose Do Rio Preto</city>
        <zip>15015-210</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076020</name>
      <address>
        <city>Sao Jose Do Rio Preto</city>
        <zip>15090-000</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076025</name>
      <address>
        <city>Sao Paulo</city>
        <zip>01244-030</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076042</name>
      <address>
        <city>Sao Paulo</city>
        <zip>01308-050</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076039</name>
      <address>
        <city>Sao Paulo</city>
        <zip>01327010</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076013</name>
      <address>
        <city>Sao Paulo</city>
        <zip>01418-100</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076023</name>
      <address>
        <city>Sao Paulo</city>
        <zip>04024-002</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076028</name>
      <address>
        <city>Sao Paulo</city>
        <zip>05403-000</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076016</name>
      <address>
        <city>Tatuí</city>
        <zip>18270-170</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 076034</name>
      <address>
        <city>Uberlandia</city>
        <zip>38400-368</zip>
        <country>Brazil</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100020</name>
      <address>
        <city>Blagoevgrad</city>
        <zip>2700</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100012</name>
      <address>
        <city>Burgas</city>
        <zip>8000</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100011</name>
      <address>
        <city>Pazardzhik</city>
        <zip>4400</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100013</name>
      <address>
        <city>Pleven</city>
        <zip>5800</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100018</name>
      <address>
        <city>Pleven</city>
        <zip>5800</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100005</name>
      <address>
        <city>Plovdiv</city>
        <zip>4002</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100015</name>
      <address>
        <city>Sandanski</city>
        <zip>2800</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100023</name>
      <address>
        <city>Smoljan</city>
        <zip>4700</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100017</name>
      <address>
        <city>Sofia</city>
        <zip>1142</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100007</name>
      <address>
        <city>Sofia</city>
        <zip>1202</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100001</name>
      <address>
        <city>Sofia</city>
        <zip>1233</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100004</name>
      <address>
        <city>Sofia</city>
        <zip>1233</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100010</name>
      <address>
        <city>Sofia</city>
        <zip>1309</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100019</name>
      <address>
        <city>Sofia</city>
        <zip>1336</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100016</name>
      <address>
        <city>Sofia</city>
        <zip>1431</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100003</name>
      <address>
        <city>Sofia</city>
        <zip>1527</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100022</name>
      <address>
        <city>Varna</city>
        <zip>9000</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 100014</name>
      <address>
        <city>Veliko Tarnovo</city>
        <zip>5000</zip>
        <country>Bulgaria</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124033</name>
      <address>
        <city>Calgary</city>
        <zip>T2N 2T8</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124017</name>
      <address>
        <city>Cambridge</city>
        <zip>N1R 7R1</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124013</name>
      <address>
        <city>Cambridge</city>
        <zip>N3H 3R8</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124026</name>
      <address>
        <city>Edmonton</city>
        <zip>T5H 3V9</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124019</name>
      <address>
        <city>Edmonton</city>
        <zip>T6G 2B7</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124016</name>
      <address>
        <city>Edmonton</city>
        <zip>T6L 5X8</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124027</name>
      <address>
        <city>Granby</city>
        <zip>J2G 1T7</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124002</name>
      <address>
        <city>Halifax</city>
        <zip>B3H 3A7</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124051</name>
      <address>
        <city>Hamilton</city>
        <zip>L8L 2X2</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124043</name>
      <address>
        <city>Joliette</city>
        <zip>J6E 6J2</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124045</name>
      <address>
        <city>Kitchener</city>
        <zip>N2M 1B2</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124053</name>
      <address>
        <city>Levis</city>
        <zip>G6V4Z5</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124015</name>
      <address>
        <city>Longueuil</city>
        <zip>J4M 2X1</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124004</name>
      <address>
        <city>Moncton</city>
        <zip>E1C 4B7</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124040</name>
      <address>
        <city>Montreal</city>
        <zip>H1T 1C8</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124032</name>
      <address>
        <city>Montreal</city>
        <zip>H2K 4L5</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124036</name>
      <address>
        <city>Montreal</city>
        <zip>H2R 1V6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124042</name>
      <address>
        <city>Montreal</city>
        <zip>H3G 1A4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124028</name>
      <address>
        <city>New Westminster</city>
        <zip>V3L 3W4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124008</name>
      <address>
        <city>Newmarket</city>
        <zip>L3Y 8C3</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124005</name>
      <address>
        <city>Oshawa</city>
        <zip>L1J 2K1</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124007</name>
      <address>
        <city>Ottawa</city>
        <zip>K1Y4W7</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124006</name>
      <address>
        <city>Penticton</city>
        <zip>V2A 3G6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124012</name>
      <address>
        <city>Red Deer</city>
        <zip>T4N 4E7</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124054</name>
      <address>
        <city>Saint-Jerome</city>
        <zip>J7Z 5T3</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124024</name>
      <address>
        <city>Sainte-Foy</city>
        <zip>G1V 4G5</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124035</name>
      <address>
        <city>Scarborough</city>
        <zip>M1E 5E9</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124047</name>
      <address>
        <city>Sherbrooke</city>
        <zip>J1H 5N4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124025</name>
      <address>
        <city>St-Georges</city>
        <zip>G5Y 4T8</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124044</name>
      <address>
        <city>St. Catherines</city>
        <zip>L2N 7L6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124034</name>
      <address>
        <city>St. John'S</city>
        <zip>A1B 3V6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124021</name>
      <address>
        <city>St. John</city>
        <zip>NBE 2L4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124009</name>
      <address>
        <city>Surrey</city>
        <zip>V3V 1N1</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124022</name>
      <address>
        <city>Sydney</city>
        <zip>B1P 1P3</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124048</name>
      <address>
        <city>Thetford Mines</city>
        <zip>G6G 2V4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124037</name>
      <address>
        <city>Thunder Bay</city>
        <zip>P7B 6V4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124001</name>
      <address>
        <city>Toronto</city>
        <zip>M5B 1W8</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124049</name>
      <address>
        <city>Trois-Rivieres</city>
        <zip>G8Z 3R6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124039</name>
      <address>
        <city>Vancouver</city>
        <zip>V5Z 1M9</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124023</name>
      <address>
        <city>Victoria</city>
        <zip>V8R 4R2</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124041</name>
      <address>
        <city>Victoria</city>
        <zip>V8T 5G4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 124038</name>
      <address>
        <city>Winnipeg</city>
        <zip>R2H 2A6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152013</name>
      <address>
        <city>Concepcion</city>
        <zip>4070038</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152003</name>
      <address>
        <city>Osorno</city>
        <zip>5311092</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152017</name>
      <address>
        <city>Punta Arenas</city>
        <zip>6210005</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152004</name>
      <address>
        <city>Santiago</city>
        <zip>7500710</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152014</name>
      <address>
        <city>Santiago</city>
        <zip>7500710</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152001</name>
      <address>
        <city>Santiago</city>
        <zip>7500922</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152019</name>
      <address>
        <city>Santiago</city>
        <zip>7650018</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152007</name>
      <address>
        <city>Santiago</city>
        <zip>7650568</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152012</name>
      <address>
        <city>Santiago</city>
        <zip>8053095</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152011</name>
      <address>
        <city>Santiago</city>
        <zip>832 0000</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152006</name>
      <address>
        <city>Santiago</city>
        <zip>8380456</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152016</name>
      <address>
        <city>Santiago</city>
        <zip>8900085</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152015</name>
      <address>
        <city>Santiago</city>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152009</name>
      <address>
        <city>Talca</city>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152002</name>
      <address>
        <city>Temuco</city>
        <zip>4781156</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152008</name>
      <address>
        <city>Valdivia</city>
        <zip>5090145</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152010</name>
      <address>
        <city>Viña Del Mar</city>
        <zip>2520000</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 152018</name>
      <address>
        <city>Viña Del Mar</city>
        <zip>2520997</zip>
        <country>Chile</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156022</name>
      <address>
        <city>Baotou</city>
        <zip>014010</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156004</name>
      <address>
        <city>Beijing</city>
        <zip>100020</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156005</name>
      <address>
        <city>Beijing</city>
        <zip>100029</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156006</name>
      <address>
        <city>Beijing</city>
        <zip>100029</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156001</name>
      <address>
        <city>Beijing</city>
        <zip>100034</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156082</name>
      <address>
        <city>Beijing</city>
        <zip>100048</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156009</name>
      <address>
        <city>Beijing</city>
        <zip>100049</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156003</name>
      <address>
        <city>Beijing</city>
        <zip>100730</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156002</name>
      <address>
        <city>Beijing</city>
        <zip>100853</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156013</name>
      <address>
        <city>Changchun</city>
        <zip>130021</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156064</name>
      <address>
        <city>Changchun</city>
        <zip>130021</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156052</name>
      <address>
        <city>Changsha</city>
        <zip>410005</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156053</name>
      <address>
        <city>Changsha</city>
        <zip>410011</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156088</name>
      <address>
        <city>Changsha</city>
        <zip>410013</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156057</name>
      <address>
        <city>Chongqing</city>
        <zip>400037</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156070</name>
      <address>
        <city>Fuzhou</city>
        <zip>350005</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156079</name>
      <address>
        <city>Fuzhou</city>
        <zip>354200</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156059</name>
      <address>
        <city>Guangzhou</city>
        <zip>510080</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156060</name>
      <address>
        <city>Guangzhou</city>
        <zip>510080</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156071</name>
      <address>
        <city>Guangzhou</city>
        <zip>510120</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156061</name>
      <address>
        <city>Guangzhou</city>
        <zip>510515</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156072</name>
      <address>
        <city>Guiyang</city>
        <zip>550002</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156047</name>
      <address>
        <city>Hangzhou</city>
        <zip>310003</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156077</name>
      <address>
        <city>Hangzhou</city>
        <zip>310006</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156048</name>
      <address>
        <city>Hangzhou</city>
        <zip>310009</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156068</name>
      <address>
        <city>Hangzhou</city>
        <zip>310013</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156078</name>
      <address>
        <city>Hangzhou</city>
        <zip>310014</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156046</name>
      <address>
        <city>Hangzhou</city>
        <zip>310016</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156020</name>
      <address>
        <city>Hohhot</city>
        <zip>010017</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156032</name>
      <address>
        <city>Jinan</city>
        <zip>250013</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156031</name>
      <address>
        <city>Jinan</city>
        <zip>250033</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156027</name>
      <address>
        <city>Lanzhou</city>
        <zip>730000</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156074</name>
      <address>
        <city>Lanzhou</city>
        <zip>730030</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156081</name>
      <address>
        <city>Luzhou</city>
        <zip>646000</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156054</name>
      <address>
        <city>Nanchang</city>
        <zip>330006</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156055</name>
      <address>
        <city>Nanchang</city>
        <zip>330006</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156034</name>
      <address>
        <city>Nanjing</city>
        <zip>210008</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156035</name>
      <address>
        <city>Nanjing</city>
        <zip>210009</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156039</name>
      <address>
        <city>Shanghai</city>
        <zip>200025</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156076</name>
      <address>
        <city>Shanghai</city>
        <zip>200030</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156044</name>
      <address>
        <city>Shanghai</city>
        <zip>200032</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156043</name>
      <address>
        <city>Shanghai</city>
        <zip>200080</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156038</name>
      <address>
        <city>Shanghai</city>
        <zip>200120</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156040</name>
      <address>
        <city>Shanghai</city>
        <zip>200233</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156016</name>
      <address>
        <city>Shenyang</city>
        <zip>110001</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156017</name>
      <address>
        <city>Shenyang</city>
        <zip>110004</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156073</name>
      <address>
        <city>Shenzhen</city>
        <zip>518020</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156084</name>
      <address>
        <city>Shenzhen</city>
        <zip>518036</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156063</name>
      <address>
        <city>Siping</city>
        <zip>136000</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156037</name>
      <address>
        <city>Suzhou</city>
        <zip>215006</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156066</name>
      <address>
        <city>Tianjin</city>
        <zip>300052</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156067</name>
      <address>
        <city>Tianjin</city>
        <zip>300121</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156083</name>
      <address>
        <city>Tianjin</city>
        <zip>300140</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156025</name>
      <address>
        <city>Tianjin</city>
        <zip>300457</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156065</name>
      <address>
        <city>Wenzhou</city>
        <zip>325000</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156051</name>
      <address>
        <city>Wuhan</city>
        <zip>430022</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156087</name>
      <address>
        <city>Wuhan</city>
        <zip>430033</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156029</name>
      <address>
        <city>Xi'An</city>
        <zip>710061</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156086</name>
      <address>
        <city>Xi'An</city>
        <zip>710068</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156062</name>
      <address>
        <city>Xuzhou</city>
        <zip>221002</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156014</name>
      <address>
        <city>Yanji</city>
        <zip>133000</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156075</name>
      <address>
        <city>Yueyang</city>
        <zip>414000</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 156080</name>
      <address>
        <city>Zhanjiang</city>
        <zip>524001</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170006</name>
      <address>
        <city>Armenia</city>
        <zip>630004</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170003</name>
      <address>
        <city>Barranquilla</city>
        <zip>08013</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170011</name>
      <address>
        <city>Barranquilla</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170013</name>
      <address>
        <city>Barranquilla</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170022</name>
      <address>
        <city>Bogota D.C.</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170018</name>
      <address>
        <city>Bogota</city>
        <zip>11001000</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170016</name>
      <address>
        <city>Bogota</city>
        <zip>111211</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170010</name>
      <address>
        <city>Cali</city>
        <zip>572</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170001</name>
      <address>
        <city>Cali</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170017</name>
      <address>
        <city>Cartagena</city>
        <zip>130010</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170004</name>
      <address>
        <city>Cartagena</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170008</name>
      <address>
        <city>Espinal - Tolima</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170005</name>
      <address>
        <city>Floridablanca</city>
        <zip>681004</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170002</name>
      <address>
        <city>Manizales</city>
        <zip>170004</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170007</name>
      <address>
        <city>Medellin</city>
        <zip>050012</zip>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170009</name>
      <address>
        <city>Medellin</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 170021</name>
      <address>
        <city>Medellin</city>
        <country>Colombia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191013</name>
      <address>
        <city>Dubrovnik</city>
        <zip>20000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191017</name>
      <address>
        <city>Krapinske Toplice</city>
        <zip>49217</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191009</name>
      <address>
        <city>Opatija</city>
        <zip>51410</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191006</name>
      <address>
        <city>Rijeka</city>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191012</name>
      <address>
        <city>Slavonski Brod</city>
        <zip>35000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191003</name>
      <address>
        <city>Varazdin</city>
        <zip>42000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191001</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191002</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191005</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191007</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191008</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191010</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191011</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191015</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191016</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 191018</name>
      <address>
        <city>Zagreb</city>
        <zip>10000</zip>
        <country>Croatia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203003</name>
      <address>
        <city>Brno</city>
        <zip>62500</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203020</name>
      <address>
        <city>Ceska Lipa</city>
        <zip>470 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203025</name>
      <address>
        <city>Cesky Krumlov</city>
        <zip>38101</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203023</name>
      <address>
        <city>Hodonin</city>
        <zip>695 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203006</name>
      <address>
        <city>Hradec Kralove</city>
        <zip>50005</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203019</name>
      <address>
        <city>Kladno</city>
        <zip>272 59</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203005</name>
      <address>
        <city>Kladno</city>
        <zip>272 80</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203008</name>
      <address>
        <city>Kromeriz</city>
        <zip>767 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203015</name>
      <address>
        <city>Liberec</city>
        <zip>46063</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203024</name>
      <address>
        <city>Marianske Lazne</city>
        <zip>353 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203013</name>
      <address>
        <city>Olomouc</city>
        <zip>77520</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203016</name>
      <address>
        <city>Ostrava</city>
        <zip>72880</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203014</name>
      <address>
        <city>Pardubice</city>
        <zip>53203</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203018</name>
      <address>
        <city>Plzen</city>
        <zip>30599</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203011</name>
      <address>
        <city>Praha 10</city>
        <zip>10034</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203017</name>
      <address>
        <city>Praha 2</city>
        <zip>12808</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203004</name>
      <address>
        <city>Praha 4</city>
        <zip>14021</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203021</name>
      <address>
        <city>Praha 4</city>
        <zip>14059</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203007</name>
      <address>
        <city>Praha 5 - Motol</city>
        <zip>15006</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203012</name>
      <address>
        <city>Praha 5</city>
        <zip>15030</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203009</name>
      <address>
        <city>Rakovnik</city>
        <zip>269 01</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 203010</name>
      <address>
        <city>Zlin</city>
        <zip>76275</zip>
        <country>Czechia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208016</name>
      <address>
        <city>Aabenraa</city>
        <zip>6200</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208012</name>
      <address>
        <city>Aalborg</city>
        <zip>9000</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208011</name>
      <address>
        <city>Aarhus N</city>
        <zip>8200</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208002</name>
      <address>
        <city>Copenhagen</city>
        <zip>2100</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208003</name>
      <address>
        <city>Glostrup</city>
        <zip>2600</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208007</name>
      <address>
        <city>Hellerup</city>
        <zip>2900</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208006</name>
      <address>
        <city>Herning</city>
        <zip>7400</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208018</name>
      <address>
        <city>Hillerød</city>
        <zip>3400</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208014</name>
      <address>
        <city>Holbaek</city>
        <zip>4300</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208013</name>
      <address>
        <city>Hvidovre</city>
        <zip>2650</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208004</name>
      <address>
        <city>Køge</city>
        <zip>4600</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208017</name>
      <address>
        <city>Næstved</city>
        <zip>4700</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208009</name>
      <address>
        <city>Odense C</city>
        <zip>5000</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208015</name>
      <address>
        <city>Silkeborg</city>
        <zip>8600</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208008</name>
      <address>
        <city>Slagelse</city>
        <zip>4200</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208001</name>
      <address>
        <city>Vejle</city>
        <zip>7100</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 208010</name>
      <address>
        <city>Viborg</city>
        <zip>8800</zip>
        <country>Denmark</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233007</name>
      <address>
        <city>Pärnu</city>
        <zip>80010</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233004</name>
      <address>
        <city>Tallinn</city>
        <zip>10138</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233002</name>
      <address>
        <city>Tallinn</city>
        <zip>11913</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233001</name>
      <address>
        <city>Tallinn</city>
        <zip>13415</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233005</name>
      <address>
        <city>Tallinn</city>
        <zip>13419</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233003</name>
      <address>
        <city>Tartu</city>
        <zip>50406</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 233006</name>
      <address>
        <city>Viljandimaa</city>
        <zip>71024</zip>
        <country>Estonia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 246004</name>
      <address>
        <city>Helsinki</city>
        <zip>00029 HUS</zip>
        <country>Finland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 246001</name>
      <address>
        <city>Oulu</city>
        <zip>90220</zip>
        <country>Finland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 246003</name>
      <address>
        <city>Tampere</city>
        <zip>33520</zip>
        <country>Finland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 246002</name>
      <address>
        <city>Turku</city>
        <zip>20520</zip>
        <country>Finland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250003</name>
      <address>
        <city>Besancon</city>
        <zip>25000</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250007</name>
      <address>
        <city>Brest Cedex</city>
        <zip>29609</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250010</name>
      <address>
        <city>Cambrai Cedex</city>
        <zip>59409</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250018</name>
      <address>
        <city>Clermont-Ferrand Cedex 1</city>
        <zip>63003</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250021</name>
      <address>
        <city>Compiegne</city>
        <zip>60321</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250002</name>
      <address>
        <city>Dijon</city>
        <zip>21000</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250001</name>
      <address>
        <city>Grenoble</city>
        <zip>38043</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250009</name>
      <address>
        <city>Limoges Cedex 1</city>
        <zip>87042</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250019</name>
      <address>
        <city>Marseille</city>
        <zip>13015</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250008</name>
      <address>
        <city>Massy</city>
        <zip>91300</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250005</name>
      <address>
        <city>Montfermeil</city>
        <zip>93370</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250023</name>
      <address>
        <city>Montpellier Cedex 5</city>
        <zip>34295</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250025</name>
      <address>
        <city>Nantes</city>
        <zip>44093</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250017</name>
      <address>
        <city>Nice Cedex 01</city>
        <zip>06002</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250015</name>
      <address>
        <city>Paris Cedex 12</city>
        <zip>75571</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250020</name>
      <address>
        <city>Paris</city>
        <zip>75013</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250012</name>
      <address>
        <city>Paris</city>
        <zip>75015</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250004</name>
      <address>
        <city>Paris</city>
        <zip>75018</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250011</name>
      <address>
        <city>Pau</city>
        <zip>64000</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250016</name>
      <address>
        <city>Pessac</city>
        <zip>33600</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250026</name>
      <address>
        <city>Rouen</city>
        <zip>76000</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 250022</name>
      <address>
        <city>Strasbourg Cedex</city>
        <zip>67091</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268004</name>
      <address>
        <city>Batumi</city>
        <zip>6010</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268001</name>
      <address>
        <city>Kutaisi</city>
        <zip>4600</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268005</name>
      <address>
        <city>Tbilisi</city>
        <zip>102</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268002</name>
      <address>
        <city>Tbilisi</city>
        <zip>159</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268003</name>
      <address>
        <city>Tbilisi</city>
        <zip>159</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268008</name>
      <address>
        <city>Tbilisi</city>
        <zip>159</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 268009</name>
      <address>
        <city>Tbilisi</city>
        <zip>159</zip>
        <country>Georgia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276013</name>
      <address>
        <city>Aachen</city>
        <zip>52074</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276019</name>
      <address>
        <city>Bad Krozingen</city>
        <zip>79189</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276008</name>
      <address>
        <city>Berlin</city>
        <zip>10789</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276040</name>
      <address>
        <city>Berlin</city>
        <zip>12203</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276051</name>
      <address>
        <city>Berlin</city>
        <zip>12559</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276039</name>
      <address>
        <city>Berlin</city>
        <zip>13347</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276025</name>
      <address>
        <city>Berlin</city>
        <zip>13509</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276054</name>
      <address>
        <city>Bernau</city>
        <zip>16321</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276037</name>
      <address>
        <city>Bielefeld</city>
        <zip>33604</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276016</name>
      <address>
        <city>Bonn</city>
        <zip>53127</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276009</name>
      <address>
        <city>Bonn</city>
        <zip>53225</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276001</name>
      <address>
        <city>Dortmund</city>
        <zip>44137</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276006</name>
      <address>
        <city>Dortmund</city>
        <zip>44137</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276031</name>
      <address>
        <city>Dortmund</city>
        <zip>44137</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276050</name>
      <address>
        <city>Dresden</city>
        <zip>01099</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276024</name>
      <address>
        <city>Eschweiler</city>
        <zip>52249</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276028</name>
      <address>
        <city>Essen</city>
        <zip>45219</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276036</name>
      <address>
        <city>Frankfurt Am Main</city>
        <zip>60594</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276012</name>
      <address>
        <city>Freiburg</city>
        <zip>79106</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276030</name>
      <address>
        <city>Halle/Saale</city>
        <zip>06120</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276032</name>
      <address>
        <city>Hamburg</city>
        <zip>20099</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276017</name>
      <address>
        <city>Hamburg</city>
        <zip>20246</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276027</name>
      <address>
        <city>Hamburg</city>
        <zip>22041</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276029</name>
      <address>
        <city>Hamm</city>
        <zip>59071</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276052</name>
      <address>
        <city>Haßloch</city>
        <zip>67454</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276014</name>
      <address>
        <city>Heidelberg</city>
        <zip>69115</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276023</name>
      <address>
        <city>Homburg/Saar</city>
        <zip>66421</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276035</name>
      <address>
        <city>Kassel</city>
        <zip>34121</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276046</name>
      <address>
        <city>Leipzig</city>
        <zip>04103</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276020</name>
      <address>
        <city>Limburg</city>
        <zip>65549</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276026</name>
      <address>
        <city>Lippstadt</city>
        <zip>59555</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276044</name>
      <address>
        <city>Lübeck</city>
        <zip>23560</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276021</name>
      <address>
        <city>Magdeburg</city>
        <zip>39120</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276015</name>
      <address>
        <city>Mainz</city>
        <zip>55131</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276010</name>
      <address>
        <city>Marburg</city>
        <zip>35043</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276018</name>
      <address>
        <city>Münster</city>
        <zip>48149</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276042</name>
      <address>
        <city>Nürnberg</city>
        <zip>90402</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276048</name>
      <address>
        <city>Peine</city>
        <zip>31224</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276053</name>
      <address>
        <city>Rotenburg An Der Fulda</city>
        <zip>36199</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276045</name>
      <address>
        <city>Rüdersdorf Bei Berlin</city>
        <zip>15562</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276002</name>
      <address>
        <city>Stuttgart</city>
        <zip>70376</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 276033</name>
      <address>
        <city>Warendorf</city>
        <zip>48231</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300001</name>
      <address>
        <city>Athens</city>
        <zip>11521</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300002</name>
      <address>
        <city>Athens</city>
        <zip>11527</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300007</name>
      <address>
        <city>Athens</city>
        <zip>16673</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300008</name>
      <address>
        <city>Chios</city>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300013</name>
      <address>
        <city>Haidari</city>
        <zip>12462</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300010</name>
      <address>
        <city>Heraklion</city>
        <zip>70013</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300005</name>
      <address>
        <city>Ioannina</city>
        <zip>45500</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300003</name>
      <address>
        <city>Marousi</city>
        <zip>151 26</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300006</name>
      <address>
        <city>N. Ionia</city>
        <zip>14233</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300004</name>
      <address>
        <city>Patra</city>
        <zip>26500</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300011</name>
      <address>
        <city>Thessaloniki</city>
        <zip>546 36</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 300009</name>
      <address>
        <city>Thessaloniki</city>
        <zip>54642</zip>
        <country>Greece</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 320003</name>
      <address>
        <city>Guatemala</city>
        <zip>01001</zip>
        <country>Guatemala</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 320001</name>
      <address>
        <city>Guatemala</city>
        <zip>01014</zip>
        <country>Guatemala</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 320002</name>
      <address>
        <city>Guatemala</city>
        <country>Guatemala</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 320004</name>
      <address>
        <city>Guatemala</city>
        <country>Guatemala</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 344003</name>
      <address>
        <city>Hong Kong</city>
        <country>Hong Kong</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 344001</name>
      <address>
        <city>Shatin, Nt</city>
        <country>Hong Kong</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348013</name>
      <address>
        <city>Balatonfüred</city>
        <zip>8230</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348002</name>
      <address>
        <city>Budapest</city>
        <zip>1023</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348012</name>
      <address>
        <city>Budapest</city>
        <zip>1106</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348005</name>
      <address>
        <city>Budapest</city>
        <zip>1122</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348006</name>
      <address>
        <city>Budapest</city>
        <zip>1134</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348008</name>
      <address>
        <city>Debrecen</city>
        <zip>4032</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348004</name>
      <address>
        <city>Eger</city>
        <zip>3300</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348003</name>
      <address>
        <city>Gyula</city>
        <zip>5700</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348010</name>
      <address>
        <city>Pécs</city>
        <zip>7624</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348009</name>
      <address>
        <city>Szeged</city>
        <zip>6725</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348007</name>
      <address>
        <city>Szekesfehervar</city>
        <zip>8000</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348011</name>
      <address>
        <city>Szombathely</city>
        <zip>9700</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 348001</name>
      <address>
        <city>Zalaegerszeg</city>
        <zip>8900</zip>
        <country>Hungary</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356060</name>
      <address>
        <city>Ahmedabad</city>
        <zip>380008</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356056</name>
      <address>
        <city>Aurangabad</city>
        <zip>431005</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356025</name>
      <address>
        <city>Bangalore</city>
        <zip>560017</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356028</name>
      <address>
        <city>Bangalore</city>
        <zip>560034</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356083</name>
      <address>
        <city>Bangalore</city>
        <zip>560038</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356018</name>
      <address>
        <city>Bangalore</city>
        <zip>560052</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356026</name>
      <address>
        <city>Bangalore</city>
        <zip>560054</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356084</name>
      <address>
        <city>Bangalore</city>
        <zip>560102</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356103</name>
      <address>
        <city>Belgaum</city>
        <zip>590010</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356019</name>
      <address>
        <city>Bikaner</city>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356013</name>
      <address>
        <city>Chennai</city>
        <zip>600 037</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356012</name>
      <address>
        <city>Chennai</city>
        <zip>600006</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356081</name>
      <address>
        <city>Chennai</city>
        <zip>603203</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356093</name>
      <address>
        <city>Delhi</city>
        <zip>110060</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356038</name>
      <address>
        <city>Delhi</city>
        <zip>110088</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356101</name>
      <address>
        <city>Gurgaon</city>
        <zip>122001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356100</name>
      <address>
        <city>Gurgaon</city>
        <zip>122002</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356035</name>
      <address>
        <city>Hyderabad</city>
        <zip>500004</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356082</name>
      <address>
        <city>Hyderabad</city>
        <zip>50063</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356015</name>
      <address>
        <city>Jaipur</city>
        <zip>302001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356053</name>
      <address>
        <city>Karad</city>
        <zip>415110</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356102</name>
      <address>
        <city>Karamsad</city>
        <zip>388325</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356022</name>
      <address>
        <city>Kochi</city>
        <zip>682018</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356106</name>
      <address>
        <city>Kolhapur</city>
        <zip>416012</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356067</name>
      <address>
        <city>Kolkata</city>
        <zip>700020</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356079</name>
      <address>
        <city>Kolkata</city>
        <zip>700027</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356069</name>
      <address>
        <city>Kolkata</city>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356089</name>
      <address>
        <city>Ludhiana</city>
        <zip>141003</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356095</name>
      <address>
        <city>Mangalore</city>
        <zip>575002</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356071</name>
      <address>
        <city>Mumbai</city>
        <zip>400022</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356057</name>
      <address>
        <city>Mumbai</city>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356007</name>
      <address>
        <city>Mysore</city>
        <zip>570001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356087</name>
      <address>
        <city>Nagpur</city>
        <zip>440010</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356098</name>
      <address>
        <city>Nagpur</city>
        <zip>440012</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356097</name>
      <address>
        <city>Nagpur</city>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356096</name>
      <address>
        <city>Nashik</city>
        <zip>422005</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356055</name>
      <address>
        <city>New Delhi</city>
        <zip>110017</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356031</name>
      <address>
        <city>New Delhi</city>
        <zip>122001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356041</name>
      <address>
        <city>Panaji</city>
        <zip>403001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356077</name>
      <address>
        <city>Pune</city>
        <zip>411001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356099</name>
      <address>
        <city>Pune</city>
        <zip>411001</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356048</name>
      <address>
        <city>Pune</city>
        <zip>411004</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356049</name>
      <address>
        <city>Pune</city>
        <zip>411004</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356050</name>
      <address>
        <city>Pune</city>
        <zip>411004</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356045</name>
      <address>
        <city>Pune</city>
        <zip>411011</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356046</name>
      <address>
        <city>Pune</city>
        <zip>411013</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356094</name>
      <address>
        <city>Pune</city>
        <zip>411019</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356042</name>
      <address>
        <city>Secunderabad, Hyderabad</city>
        <zip>500003</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356009</name>
      <address>
        <city>Secunderabad</city>
        <zip>500 003</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356032</name>
      <address>
        <city>Secunderabad</city>
        <zip>500003</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356091</name>
      <address>
        <city>Surat</city>
        <zip>395002</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356002</name>
      <address>
        <city>Vijayawada</city>
        <zip>520008</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356105</name>
      <address>
        <city>Vijaywada</city>
        <zip>520002</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356033</name>
      <address>
        <city>Visakhapatnam</city>
        <zip>530002</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356039</name>
      <address>
        <city>Vishkhapattanam</city>
        <zip>530013</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 356104</name>
      <address>
        <city>Wardha</city>
        <zip>442004</zip>
        <country>India</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376006</name>
      <address>
        <city>Afula</city>
        <zip>18101</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376024</name>
      <address>
        <city>Afula</city>
        <zip>18101</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376009</name>
      <address>
        <city>Ashkelon</city>
        <zip>78278</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376012</name>
      <address>
        <city>Beer Sheva</city>
        <zip>84101</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376011</name>
      <address>
        <city>Haifa</city>
        <zip>31048</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376017</name>
      <address>
        <city>Haifa</city>
        <zip>31048</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376025</name>
      <address>
        <city>Haifa</city>
        <zip>31048</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376018</name>
      <address>
        <city>Haifa</city>
        <zip>31096</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376007</name>
      <address>
        <city>Holon</city>
        <zip>58100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376021</name>
      <address>
        <city>Holon</city>
        <zip>58100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376016</name>
      <address>
        <city>Jerusalem</city>
        <zip>91031</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376005</name>
      <address>
        <city>Jerusalem</city>
        <zip>91120</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376027</name>
      <address>
        <city>Jerusalem</city>
        <zip>91120</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376002</name>
      <address>
        <city>Kfar Saba</city>
        <zip>44281</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376013</name>
      <address>
        <city>Kfar Saba</city>
        <zip>44281</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376004</name>
      <address>
        <city>Nahariya</city>
        <zip>22100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376015</name>
      <address>
        <city>Nazareth</city>
        <zip>16100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376001</name>
      <address>
        <city>Petah-Tikva</city>
        <zip>49100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376019</name>
      <address>
        <city>Petah-Tikva</city>
        <zip>49100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376020</name>
      <address>
        <city>Rehovot</city>
        <zip>76100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376003</name>
      <address>
        <city>Safed</city>
        <zip>13100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376008</name>
      <address>
        <city>Safed</city>
        <zip>13100</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376010</name>
      <address>
        <city>Tel Aviv</city>
        <zip>64239</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376014</name>
      <address>
        <city>Tel Aviv</city>
        <zip>64239</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376022</name>
      <address>
        <city>Tel Hashomer</city>
        <zip>52621</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376023</name>
      <address>
        <city>Tiberias</city>
        <zip>15208</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 376026</name>
      <address>
        <city>Tzrifin</city>
        <zip>70300</zip>
        <country>Israel</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380019</name>
      <address>
        <city>Augusta</city>
        <zip>96100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380017</name>
      <address>
        <city>Bergamo</city>
        <zip>24127</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380026</name>
      <address>
        <city>Brescia</city>
        <zip>25123</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380008</name>
      <address>
        <city>Brescia</city>
        <zip>25124</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380012</name>
      <address>
        <city>Ferrara</city>
        <zip>44100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380027</name>
      <address>
        <city>Forlì</city>
        <zip>47100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380015</name>
      <address>
        <city>Livorno</city>
        <zip>57125</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380033</name>
      <address>
        <city>Massa</city>
        <zip>54100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380030</name>
      <address>
        <city>Milano</city>
        <zip>20132</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380005</name>
      <address>
        <city>Milano</city>
        <zip>20138</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380003</name>
      <address>
        <city>Milano</city>
        <zip>20148</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380025</name>
      <address>
        <city>Monza</city>
        <zip>20900</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380001</name>
      <address>
        <city>Napoli</city>
        <zip>80100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380002</name>
      <address>
        <city>Napoli</city>
        <zip>80131</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380021</name>
      <address>
        <city>Novara</city>
        <zip>28100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380009</name>
      <address>
        <city>Osio Sotto</city>
        <zip>24040</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380007</name>
      <address>
        <city>Palermo</city>
        <zip>90127</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380013</name>
      <address>
        <city>Perugia</city>
        <zip>06132</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380031</name>
      <address>
        <city>Rho</city>
        <zip>20017</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380014</name>
      <address>
        <city>Rimini</city>
        <zip>47900</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380024</name>
      <address>
        <city>Roma</city>
        <zip>00152</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380028</name>
      <address>
        <city>Seriate</city>
        <zip>24068</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380032</name>
      <address>
        <city>Treviso</city>
        <zip>31100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 380020</name>
      <address>
        <city>Vittorio Veneto</city>
        <zip>31029</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392013</name>
      <address>
        <city>Amagasaki-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392041</name>
      <address>
        <city>Amagasaki-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392029</name>
      <address>
        <city>Fukuoka-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392019</name>
      <address>
        <city>Hachioji-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392026</name>
      <address>
        <city>Higashihiroshima-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392024</name>
      <address>
        <city>Higashiibaraki-Gun</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392003</name>
      <address>
        <city>Hiroshima-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392002</name>
      <address>
        <city>Itabashi-Ku</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392014</name>
      <address>
        <city>Itabashi-Ku</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392033</name>
      <address>
        <city>Izumisano-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392020</name>
      <address>
        <city>Kanazawa-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392015</name>
      <address>
        <city>Kitakyushu-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392017</name>
      <address>
        <city>Kobe-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392028</name>
      <address>
        <city>Kobe-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392037</name>
      <address>
        <city>Kobe-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392025</name>
      <address>
        <city>Koga-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392010</name>
      <address>
        <city>Komatsu-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392035</name>
      <address>
        <city>Komatsushima-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392023</name>
      <address>
        <city>Kumamoto-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392031</name>
      <address>
        <city>Kumamoto-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392039</name>
      <address>
        <city>Kure-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392012</name>
      <address>
        <city>Kurume-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392032</name>
      <address>
        <city>Kusatsu-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392001</name>
      <address>
        <city>Kyoto City</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392027</name>
      <address>
        <city>Minato-Ku</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392016</name>
      <address>
        <city>Morioka-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392005</name>
      <address>
        <city>Nagoya-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392022</name>
      <address>
        <city>Nerima-Ku</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392009</name>
      <address>
        <city>Osaka-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392011</name>
      <address>
        <city>Osaka-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392040</name>
      <address>
        <city>Osaka-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392004</name>
      <address>
        <city>Sagamihara-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392036</name>
      <address>
        <city>Sapporo-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392034</name>
      <address>
        <city>Shinagawa-Ku</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392018</name>
      <address>
        <city>Suita-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392030</name>
      <address>
        <city>Tokushima-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392008</name>
      <address>
        <city>Urasoe-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392006</name>
      <address>
        <city>Yokohama-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 392021</name>
      <address>
        <city>Yokohama-Shi</city>
        <country>Japan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410013</name>
      <address>
        <city>Busan</city>
        <zip>602-715</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410003</name>
      <address>
        <city>Busan</city>
        <zip>602-739</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410002</name>
      <address>
        <city>Daegu</city>
        <zip>700-721</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410012</name>
      <address>
        <city>Goyang-Si</city>
        <zip>10326</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410001</name>
      <address>
        <city>Gwangju</city>
        <zip>501-757</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410008</name>
      <address>
        <city>Seongnam</city>
        <zip>463-707</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410004</name>
      <address>
        <city>Seoul</city>
        <zip>06591</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410007</name>
      <address>
        <city>Seoul</city>
        <zip>07061</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410010</name>
      <address>
        <city>Seoul</city>
        <zip>110-744</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410011</name>
      <address>
        <city>Seoul</city>
        <zip>134-727</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410006</name>
      <address>
        <city>Seoul</city>
        <zip>152-703</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410009</name>
      <address>
        <city>Suwon</city>
        <zip>443-721</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 410005</name>
      <address>
        <city>Wonju</city>
        <zip>220-701</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 428004</name>
      <address>
        <city>Daugavpils</city>
        <zip>LV-5417</zip>
        <country>Latvia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 428002</name>
      <address>
        <city>Liepaja</city>
        <zip>LV-3414</zip>
        <country>Latvia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 428006</name>
      <address>
        <city>Riga</city>
        <zip>LV-1002</zip>
        <country>Latvia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 428001</name>
      <address>
        <city>Riga</city>
        <zip>LV-1011</zip>
        <country>Latvia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 428005</name>
      <address>
        <city>Riga</city>
        <zip>LV-1038</zip>
        <country>Latvia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 428003</name>
      <address>
        <city>Ventspils</city>
        <zip>LV-3601</zip>
        <country>Latvia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440004</name>
      <address>
        <city>Kaunas</city>
        <zip>50009</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440005</name>
      <address>
        <city>Kaunas</city>
        <zip>50009</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440009</name>
      <address>
        <city>Kaunas</city>
        <zip>50128</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440008</name>
      <address>
        <city>Kaunas</city>
        <zip>50177</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440001</name>
      <address>
        <city>Klaipeda</city>
        <zip>LT-91131</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440006</name>
      <address>
        <city>Klaipeda</city>
        <zip>LT-92288</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440002</name>
      <address>
        <city>Vilnius</city>
        <zip>07157</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440007</name>
      <address>
        <city>Vilnius</city>
        <zip>10309</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 440003</name>
      <address>
        <city>Vilnius</city>
        <zip>LT-08661</zip>
        <country>Lithuania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 807005</name>
      <address>
        <city>Bitola</city>
        <zip>7000</zip>
        <country>Macedonia, The Former Yugoslav Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 807004</name>
      <address>
        <city>Shtip</city>
        <zip>2000</zip>
        <country>Macedonia, The Former Yugoslav Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 807002</name>
      <address>
        <city>Skopje</city>
        <zip>1000</zip>
        <country>Macedonia, The Former Yugoslav Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 807001</name>
      <address>
        <city>Skopje</city>
        <zip>1109</zip>
        <country>Macedonia, The Former Yugoslav Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 807003</name>
      <address>
        <city>Tetovo</city>
        <zip>1200</zip>
        <country>Macedonia, The Former Yugoslav Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458004</name>
      <address>
        <city>Batu Caves</city>
        <zip>68100</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458007</name>
      <address>
        <city>Kota Bharu</city>
        <zip>16150</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458006</name>
      <address>
        <city>Kota Kinabalu</city>
        <zip>88300</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458002</name>
      <address>
        <city>Kuala Lumpur</city>
        <zip>50400</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458005</name>
      <address>
        <city>Kuala Lumpur</city>
        <zip>56000</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458003</name>
      <address>
        <city>Kuching</city>
        <zip>94300</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 458001</name>
      <address>
        <city>Sungai Buloh</city>
        <zip>47000</zip>
        <country>Malaysia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484005</name>
      <address>
        <city>Aguascalientes</city>
        <zip>20230</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484015</name>
      <address>
        <city>Aguascalientes</city>
        <zip>20230</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484004</name>
      <address>
        <city>Culiacan</city>
        <zip>80020</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484003</name>
      <address>
        <city>Durango</city>
        <zip>34000</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484010</name>
      <address>
        <city>Guadalajara</city>
        <zip>44100</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484006</name>
      <address>
        <city>Guadalajara</city>
        <zip>44210</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484008</name>
      <address>
        <city>Jalapa</city>
        <zip>91020</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484019</name>
      <address>
        <city>Mexico D.F.</city>
        <zip>14080</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484023</name>
      <address>
        <city>Mexico Df</city>
        <zip>11850</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484027</name>
      <address>
        <city>Mexico</city>
        <zip>06720</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484013</name>
      <address>
        <city>Monterrey</city>
        <zip>64020</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484018</name>
      <address>
        <city>Monterrey</city>
        <zip>64060</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484011</name>
      <address>
        <city>Monterrey</city>
        <zip>64460</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484007</name>
      <address>
        <city>Monterrey</city>
        <zip>64710</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484017</name>
      <address>
        <city>Morelia</city>
        <zip>58260</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484012</name>
      <address>
        <city>Oaxaca</city>
        <zip>68000</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484014</name>
      <address>
        <city>Querétaro</city>
        <zip>76000</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484009</name>
      <address>
        <city>San Luis Potosi</city>
        <zip>72244</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484002</name>
      <address>
        <city>Tijuana</city>
        <zip>22500</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 484020</name>
      <address>
        <city>Toluca</city>
        <zip>50130</zip>
        <country>Mexico</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528006</name>
      <address>
        <city>Alkmaar</city>
        <zip>1815 JD</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528022</name>
      <address>
        <city>Amsterdam</city>
        <zip>1061 AE</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528026</name>
      <address>
        <city>Amsterdam</city>
        <zip>1091 AC</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528021</name>
      <address>
        <city>Apeldoorn</city>
        <zip>7314 ET</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528029</name>
      <address>
        <city>Arnhem</city>
        <zip>6815 AD</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528004</name>
      <address>
        <city>Breda</city>
        <zip>4818 CK</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528002</name>
      <address>
        <city>Delft</city>
        <zip>2625 AD</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528007</name>
      <address>
        <city>Eindhoven</city>
        <zip>5602 ZA</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528032</name>
      <address>
        <city>Goes</city>
        <zip>4462 RA</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528012</name>
      <address>
        <city>Gouda</city>
        <zip>2803 HH</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528001</name>
      <address>
        <city>Groningen</city>
        <zip>9728 NT</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528025</name>
      <address>
        <city>Haarlem</city>
        <zip>2035 RC</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528023</name>
      <address>
        <city>Hardenberg</city>
        <zip>7702 SE</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528024</name>
      <address>
        <city>Heerenveen</city>
        <zip>8441PW</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528016</name>
      <address>
        <city>Hoorn</city>
        <zip>1624 NP</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528019</name>
      <address>
        <city>Leeuwarden</city>
        <zip>8934 AD</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528008</name>
      <address>
        <city>Leiden</city>
        <zip>2333 ZA</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528017</name>
      <address>
        <city>Meppel</city>
        <zip>7943 KA</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528030</name>
      <address>
        <city>Nieuwegein</city>
        <zip>3435 CM</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528011</name>
      <address>
        <city>Nijmegen</city>
        <zip>6500 HB</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528015</name>
      <address>
        <city>Purmerend</city>
        <zip>1441RN</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528018</name>
      <address>
        <city>Roosendaal</city>
        <zip>4708 AE</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528014</name>
      <address>
        <city>Rotterdam</city>
        <zip>3045 PM</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528027</name>
      <address>
        <city>Rotterdam</city>
        <zip>3079</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528005</name>
      <address>
        <city>Sneek</city>
        <zip>8601</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528034</name>
      <address>
        <city>Tiel</city>
        <zip>4002 WP</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528013</name>
      <address>
        <city>Tilburg</city>
        <zip>5022 GC</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528028</name>
      <address>
        <city>Uden</city>
        <zip>5406 PT</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528009</name>
      <address>
        <city>Venlo</city>
        <zip>5912 BL</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528033</name>
      <address>
        <city>Zaandam</city>
        <zip>1502 DV</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528031</name>
      <address>
        <city>Zutphen</city>
        <zip>7207 AE</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 528020</name>
      <address>
        <city>Zwolle</city>
        <zip>8011 JW</zip>
        <country>Netherlands</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554010</name>
      <address>
        <city>Auckland</city>
        <zip>1023</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554001</name>
      <address>
        <city>Christchurch</city>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554006</name>
      <address>
        <city>Dunedin</city>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554004</name>
      <address>
        <city>Hamilton</city>
        <zip>3200</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554011</name>
      <address>
        <city>Lower Hutt</city>
        <zip>5010</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554005</name>
      <address>
        <city>Nelson</city>
        <zip>7010</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554007</name>
      <address>
        <city>New Plymouth</city>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554002</name>
      <address>
        <city>Otahuhu</city>
        <zip>2025</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554008</name>
      <address>
        <city>Palmerston North</city>
        <zip>4414</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554012</name>
      <address>
        <city>Rotorua</city>
        <zip>3010</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554009</name>
      <address>
        <city>Takapuna</city>
        <zip>1309</zip>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 554003</name>
      <address>
        <city>Wellington</city>
        <country>New Zealand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578004</name>
      <address>
        <city>Arendal</city>
        <zip>4809</zip>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578013</name>
      <address>
        <city>Bergen</city>
        <zip>5021</zip>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578009</name>
      <address>
        <city>Hamar</city>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578006</name>
      <address>
        <city>Kongsvinger</city>
        <zip>2226</zip>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578003</name>
      <address>
        <city>Oslo</city>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578005</name>
      <address>
        <city>Oslo</city>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578012</name>
      <address>
        <city>Stavanger</city>
        <zip>4068</zip>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578002</name>
      <address>
        <city>Svelvik</city>
        <zip>3060</zip>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 578011</name>
      <address>
        <city>Tynset</city>
        <zip>2500</zip>
        <country>Norway</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604018</name>
      <address>
        <city>Arequipa</city>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604004</name>
      <address>
        <city>Callao</city>
        <zip>CALLAO 02</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604025</name>
      <address>
        <city>Callao</city>
        <zip>Callao 02</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604022</name>
      <address>
        <city>Cuzco</city>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604013</name>
      <address>
        <city>Ica</city>
        <zip>11001</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604010</name>
      <address>
        <city>Lima</city>
        <zip>051</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604008</name>
      <address>
        <city>Lima</city>
        <zip>27</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604001</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 01</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604007</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 01</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604005</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 10</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604006</name>
      <address>
        <city>Lima</city>
        <zip>Lima 11</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604015</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 18</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604016</name>
      <address>
        <city>Lima</city>
        <zip>Lima 18</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604017</name>
      <address>
        <city>Lima</city>
        <zip>Lima 27</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604019</name>
      <address>
        <city>Lima</city>
        <zip>Lima 27</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604003</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 29</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604024</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 31</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604012</name>
      <address>
        <city>Lima</city>
        <zip>LIMA 32</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604020</name>
      <address>
        <city>Piura</city>
        <zip>20001</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 604023</name>
      <address>
        <city>Trujillo</city>
        <zip>13001</zip>
        <country>Peru</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608012</name>
      <address>
        <city>Cavite</city>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608003</name>
      <address>
        <city>Cebu City</city>
        <zip>6000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608013</name>
      <address>
        <city>Cebu City</city>
        <zip>6000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608011</name>
      <address>
        <city>Davao City</city>
        <zip>8000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608010</name>
      <address>
        <city>Davao</city>
        <zip>8000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608006</name>
      <address>
        <city>Iloilo City</city>
        <zip>5000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608002</name>
      <address>
        <city>Makati City</city>
        <zip>1218</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608004</name>
      <address>
        <city>Manila</city>
        <zip>1000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608014</name>
      <address>
        <city>Manila</city>
        <zip>1000</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608001</name>
      <address>
        <city>Quezon City</city>
        <zip>1100</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608009</name>
      <address>
        <city>Quezon City</city>
        <zip>1109</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608005</name>
      <address>
        <city>Quezon</city>
        <zip>1102</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 608008</name>
      <address>
        <city>San Juan</city>
        <zip>1500</zip>
        <country>Philippines</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616026</name>
      <address>
        <city>Bydgoszcz</city>
        <zip>85-094</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616029</name>
      <address>
        <city>Bydgoszcz</city>
        <zip>85-681</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616010</name>
      <address>
        <city>Chrzanow</city>
        <zip>40-635</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616036</name>
      <address>
        <city>Czeladz</city>
        <zip>41-250</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616034</name>
      <address>
        <city>Gdansk</city>
        <zip>80-462</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616015</name>
      <address>
        <city>Gdansk</city>
        <zip>80-952</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616035</name>
      <address>
        <city>Gdynia</city>
        <zip>81-394</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616005</name>
      <address>
        <city>Gdynia</city>
        <zip>81-402</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616033</name>
      <address>
        <city>Gdynia</city>
        <zip>81-472</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616037</name>
      <address>
        <city>Grodzisk Mazowiecki</city>
        <zip>05-825</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616030</name>
      <address>
        <city>Jelenia Gora</city>
        <zip>58-506</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616031</name>
      <address>
        <city>Krakow</city>
        <zip>30-901</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616002</name>
      <address>
        <city>Krakow</city>
        <zip>31-121</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616012</name>
      <address>
        <city>Leczna</city>
        <zip>21-010</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616017</name>
      <address>
        <city>Legnica</city>
        <zip>59-220</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616019</name>
      <address>
        <city>Lodz</city>
        <zip>91-078</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616016</name>
      <address>
        <city>Lubin</city>
        <zip>59-301</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616021</name>
      <address>
        <city>Olawa</city>
        <zip>55-200</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616039</name>
      <address>
        <city>Olsztyn</city>
        <zip>10-561</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616003</name>
      <address>
        <city>Plock</city>
        <zip>09-402</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616011</name>
      <address>
        <city>Poznan</city>
        <zip>61-289</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616018</name>
      <address>
        <city>Pulawy</city>
        <zip>24-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616006</name>
      <address>
        <city>Skierniewice</city>
        <zip>96-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616027</name>
      <address>
        <city>Sobotka</city>
        <zip>55-050</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616007</name>
      <address>
        <city>Sokolka</city>
        <zip>16-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616022</name>
      <address>
        <city>Swidnik</city>
        <zip>21-040</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616024</name>
      <address>
        <city>Szczecin</city>
        <zip>70-506</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616004</name>
      <address>
        <city>Torun</city>
        <zip>87-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616013</name>
      <address>
        <city>Torun</city>
        <zip>87-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616025</name>
      <address>
        <city>Torun</city>
        <zip>87-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616032</name>
      <address>
        <city>W?Grów</city>
        <zip>07-100</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616040</name>
      <address>
        <city>Warszawa</city>
        <zip>00-444</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616020</name>
      <address>
        <city>Warszawa</city>
        <zip>01-142</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616038</name>
      <address>
        <city>Warszawa</city>
        <zip>02-672</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616008</name>
      <address>
        <city>Warszawa</city>
        <zip>04-073</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 616041</name>
      <address>
        <city>Wroclaw</city>
        <zip>50-315</zip>
        <country>Poland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620004</name>
      <address>
        <city>Almada</city>
        <zip>2801-951</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620005</name>
      <address>
        <city>Aveiro</city>
        <zip>3814-501</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620011</name>
      <address>
        <city>Coimbra</city>
        <zip>3000-075</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620008</name>
      <address>
        <city>Coimbra</city>
        <zip>3041-801</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620001</name>
      <address>
        <city>Leiria</city>
        <zip>2410-197</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620003</name>
      <address>
        <city>Ponta Delgada</city>
        <zip>9500-370</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620002</name>
      <address>
        <city>Setubal</city>
        <zip>2910-446</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620010</name>
      <address>
        <city>Vila Franca De Xira</city>
        <zip>2600-009</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 620006</name>
      <address>
        <city>Vila Nova Gaia</city>
        <zip>4434-502</zip>
        <country>Portugal</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642001</name>
      <address>
        <city>Braila</city>
        <zip>810249</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642003</name>
      <address>
        <city>Bucharest</city>
        <zip>010242</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642012</name>
      <address>
        <city>Bucuresti</city>
        <zip>011234</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642021</name>
      <address>
        <city>Bucuresti</city>
        <zip>011461</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642007</name>
      <address>
        <city>Bucuresti</city>
        <zip>014461</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642008</name>
      <address>
        <city>Bucuresti</city>
        <zip>10416</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642005</name>
      <address>
        <city>Buzau</city>
        <zip>120203</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642013</name>
      <address>
        <city>Codlea</city>
        <zip>505100</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642004</name>
      <address>
        <city>Constanta</city>
        <zip>900591</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642002</name>
      <address>
        <city>Craiova</city>
        <zip>200147</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642016</name>
      <address>
        <city>Craiova</city>
        <zip>200642</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642010</name>
      <address>
        <city>Focsani</city>
        <zip>620034</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642017</name>
      <address>
        <city>Iasi</city>
        <zip>700786</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642006</name>
      <address>
        <city>Targoviste</city>
        <zip>130083</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642019</name>
      <address>
        <city>Targu Mures</city>
        <zip>540136</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642015</name>
      <address>
        <city>Targu Mures</city>
        <zip>540143</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 642018</name>
      <address>
        <city>Timisoara</city>
        <zip>300736</zip>
        <country>Romania</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643027</name>
      <address>
        <city>Barnaul</city>
        <zip>656055</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643037</name>
      <address>
        <city>Kazan</city>
        <zip>420012</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643013</name>
      <address>
        <city>Kemerovo</city>
        <zip>650002</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643020</name>
      <address>
        <city>Krasnodar</city>
        <zip>350042</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643053</name>
      <address>
        <city>Krasnodar</city>
        <zip>350086</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643033</name>
      <address>
        <city>Moscow</city>
        <zip>101990</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643002</name>
      <address>
        <city>Moscow</city>
        <zip>111539</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643011</name>
      <address>
        <city>Moscow</city>
        <zip>117292</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643029</name>
      <address>
        <city>Moscow</city>
        <zip>121356</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643028</name>
      <address>
        <city>Moscow</city>
        <zip>121552</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643004</name>
      <address>
        <city>Moscow</city>
        <zip>125284</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643016</name>
      <address>
        <city>Moscow</city>
        <zip>125284</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643023</name>
      <address>
        <city>Moscow</city>
        <zip>127473</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643044</name>
      <address>
        <city>Moscow</city>
        <zip>127644</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643022</name>
      <address>
        <city>Moscow</city>
        <zip>129301</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643031</name>
      <address>
        <city>Moscow</city>
        <zip>129327</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643043</name>
      <address>
        <city>Nizhny Novgorod</city>
        <zip>603005</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643034</name>
      <address>
        <city>Novosibirsk</city>
        <zip>630075</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643052</name>
      <address>
        <city>Novosibirsk</city>
        <zip>630089</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643050</name>
      <address>
        <city>Novosibirsk</city>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643035</name>
      <address>
        <city>Omsk</city>
        <zip>644112</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643039</name>
      <address>
        <city>Perm</city>
        <zip>614077</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643008</name>
      <address>
        <city>Rostov-Na-Donu</city>
        <zip>344068</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643017</name>
      <address>
        <city>Ryazan</city>
        <zip>390026</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643006</name>
      <address>
        <city>Saint - Petersburg</city>
        <zip>190013</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643015</name>
      <address>
        <city>Saint - Petersburg</city>
        <zip>190013</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643001</name>
      <address>
        <city>Saint Petersburg</city>
        <zip>194044</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643007</name>
      <address>
        <city>Saint Petersburg</city>
        <zip>196601</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643051</name>
      <address>
        <city>Saint-Petersburg</city>
        <zip>192242</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643042</name>
      <address>
        <city>Saint-Petersburg</city>
        <zip>194354</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643040</name>
      <address>
        <city>Saint-Petersburg</city>
        <zip>197022</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643012</name>
      <address>
        <city>Saratov</city>
        <zip>410028</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643021</name>
      <address>
        <city>Saratov</city>
        <zip>410028</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643003</name>
      <address>
        <city>Saratov</city>
        <zip>410053</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643014</name>
      <address>
        <city>Saratov</city>
        <zip>410054</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643030</name>
      <address>
        <city>St-Petersburg</city>
        <zip>194044</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643010</name>
      <address>
        <city>St-Petersburg</city>
        <zip>194291</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643054</name>
      <address>
        <city>St-Petersburg</city>
        <zip>199106</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643049</name>
      <address>
        <city>Tomsk</city>
        <zip>634012</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643019</name>
      <address>
        <city>Tyumen</city>
        <zip>625000</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643025</name>
      <address>
        <city>Tyumen</city>
        <zip>625026</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643045</name>
      <address>
        <city>Voronezh</city>
        <zip>394065</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 643009</name>
      <address>
        <city>Yaroslavl</city>
        <zip>150029</zip>
        <country>Russian Federation</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688003</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688005</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688006</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688007</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688008</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688010</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688011</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688013</name>
      <address>
        <city>Belgrade</city>
        <zip>11000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688015</name>
      <address>
        <city>Belgrade</city>
        <zip>11050</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688002</name>
      <address>
        <city>Belgrade</city>
        <zip>11080</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688012</name>
      <address>
        <city>Kragujevac</city>
        <zip>34000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688016</name>
      <address>
        <city>Leskovac</city>
        <zip>16000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688001</name>
      <address>
        <city>Niska Banja</city>
        <zip>18205</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688004</name>
      <address>
        <city>Nis</city>
        <zip>18000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688018</name>
      <address>
        <city>Pancevo</city>
        <zip>26 000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688009</name>
      <address>
        <city>Sremska Kamenica</city>
        <zip>21204</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688017</name>
      <address>
        <city>Sremska Mitrovica</city>
        <zip>22000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 688014</name>
      <address>
        <city>Valjevo</city>
        <zip>14000</zip>
        <country>Serbia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 702002</name>
      <address>
        <city>Singapore</city>
        <zip>119228</zip>
        <country>Singapore</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 702003</name>
      <address>
        <city>Singapore</city>
        <zip>159964</zip>
        <country>Singapore</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 702001</name>
      <address>
        <city>Singapore</city>
        <zip>168752</zip>
        <country>Singapore</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703001</name>
      <address>
        <city>Bardejov</city>
        <zip>085 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703008</name>
      <address>
        <city>Bratislava</city>
        <zip>821 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703020</name>
      <address>
        <city>Bratislava</city>
        <zip>821 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703014</name>
      <address>
        <city>Bratislava</city>
        <zip>826 06</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703013</name>
      <address>
        <city>Bratislava</city>
        <zip>841 08</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703023</name>
      <address>
        <city>Dolny Kubin</city>
        <zip>02601</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703002</name>
      <address>
        <city>Kosice</city>
        <zip>040 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703009</name>
      <address>
        <city>Kosice</city>
        <zip>040 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703016</name>
      <address>
        <city>Kosice</city>
        <zip>040 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703019</name>
      <address>
        <city>Kosice</city>
        <zip>04001</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703007</name>
      <address>
        <city>Kosice</city>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703012</name>
      <address>
        <city>Kralovsky Chlmec</city>
        <zip>077 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703006</name>
      <address>
        <city>Lucenec</city>
        <zip>984 39</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703010</name>
      <address>
        <city>Lucenec</city>
        <zip>98401</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703003</name>
      <address>
        <city>Nitra</city>
        <zip>950 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703004</name>
      <address>
        <city>Presov</city>
        <zip>080 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703018</name>
      <address>
        <city>Svidnik</city>
        <zip>089 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703022</name>
      <address>
        <city>Trebisov</city>
        <zip>075 01</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 703005</name>
      <address>
        <city>Zilina</city>
        <zip>01001</zip>
        <country>Slovakia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 705001</name>
      <address>
        <city>Celje</city>
        <zip>3000</zip>
        <country>Slovenia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 705004</name>
      <address>
        <city>Izola</city>
        <zip>6310</zip>
        <country>Slovenia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 705002</name>
      <address>
        <city>Jesenice</city>
        <zip>4270</zip>
        <country>Slovenia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 705005</name>
      <address>
        <city>Ljubljana</city>
        <zip>1525</zip>
        <country>Slovenia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 705006</name>
      <address>
        <city>Ljubljana</city>
        <zip>SI-1525</zip>
        <country>Slovenia</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710017</name>
      <address>
        <city>Alberton</city>
        <zip>1450</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710007</name>
      <address>
        <city>Bellville</city>
        <zip>7530</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710015</name>
      <address>
        <city>Bloemfontein</city>
        <zip>9300</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710009</name>
      <address>
        <city>Cape Town</city>
        <zip>7405</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710010</name>
      <address>
        <city>Cape Town</city>
        <zip>7925</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710005</name>
      <address>
        <city>Chatsworth</city>
        <zip>4091</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710006</name>
      <address>
        <city>Durban</city>
        <zip>4001</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710004</name>
      <address>
        <city>Durban</city>
        <zip>4052</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710002</name>
      <address>
        <city>Durban</city>
        <zip>4320</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710012</name>
      <address>
        <city>Johannesburg</city>
        <zip>2193</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710014</name>
      <address>
        <city>Johannesburg</city>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710019</name>
      <address>
        <city>Kempton Park</city>
        <zip>1619</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710011</name>
      <address>
        <city>Kimberley</city>
        <zip>8301</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710021</name>
      <address>
        <city>Kuils River</city>
        <zip>7580</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710018</name>
      <address>
        <city>Parow</city>
        <zip>7500</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710008</name>
      <address>
        <city>Pretoria</city>
        <zip>0040</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710016</name>
      <address>
        <city>Pretoria</city>
        <zip>0157</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710020</name>
      <address>
        <city>Stellenbosch</city>
        <zip>7600</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710013</name>
      <address>
        <city>Tongaat</city>
        <zip>4400</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710022</name>
      <address>
        <city>Western Cape</city>
        <zip>7500</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 710003</name>
      <address>
        <city>Worcester</city>
        <zip>6850</zip>
        <country>South Africa</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724010</name>
      <address>
        <city>Alcalá De Henares</city>
        <zip>28805</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724007</name>
      <address>
        <city>Almería</city>
        <zip>04120</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724037</name>
      <address>
        <city>Barcelona</city>
        <zip>08003</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724041</name>
      <address>
        <city>Barcelona</city>
        <zip>08025</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724038</name>
      <address>
        <city>Barcelona</city>
        <zip>08035</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724008</name>
      <address>
        <city>Barcelona</city>
        <zip>08036</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724039</name>
      <address>
        <city>Cáceres</city>
        <zip>10003</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724042</name>
      <address>
        <city>Córdoba</city>
        <zip>14004</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724027</name>
      <address>
        <city>Fuenlabrada</city>
        <zip>28942</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724002</name>
      <address>
        <city>Girona</city>
        <zip>17007</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724013</name>
      <address>
        <city>Granada</city>
        <zip>18014</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724032</name>
      <address>
        <city>Guadalajara</city>
        <zip>19002</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724025</name>
      <address>
        <city>Hospitalet De Llobregat</city>
        <zip>08907</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724003</name>
      <address>
        <city>Huelva</city>
        <zip>21005</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724021</name>
      <address>
        <city>León</city>
        <zip>24071</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724026</name>
      <address>
        <city>Lleida</city>
        <zip>25198</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724006</name>
      <address>
        <city>Lugo</city>
        <zip>27003</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724030</name>
      <address>
        <city>Madrid</city>
        <zip>28006</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724020</name>
      <address>
        <city>Madrid</city>
        <zip>28031</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724015</name>
      <address>
        <city>Madrid</city>
        <zip>28034</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724031</name>
      <address>
        <city>Madrid</city>
        <zip>28040</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724033</name>
      <address>
        <city>Madrid</city>
        <zip>28040</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724017</name>
      <address>
        <city>Madrid</city>
        <zip>28922</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724035</name>
      <address>
        <city>Majadahonda</city>
        <zip>28222</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724036</name>
      <address>
        <city>Murcia</city>
        <zip>30120</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724016</name>
      <address>
        <city>Málaga</city>
        <zip>29010</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724043</name>
      <address>
        <city>Málaga</city>
        <zip>29010</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724001</name>
      <address>
        <city>Oviedo</city>
        <zip>33011</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724022</name>
      <address>
        <city>Sabadell</city>
        <zip>08208</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724029</name>
      <address>
        <city>San Sebastian De Los Reyes</city>
        <zip>28702</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724028</name>
      <address>
        <city>Santander</city>
        <zip>39008</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724034</name>
      <address>
        <city>Santiago De Compostela</city>
        <zip>15706</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724014</name>
      <address>
        <city>Sevilla</city>
        <zip>41071</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724024</name>
      <address>
        <city>Tarragona</city>
        <zip>43007</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724019</name>
      <address>
        <city>Valencia</city>
        <zip>46010</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724009</name>
      <address>
        <city>Valencia</city>
        <zip>46015</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724011</name>
      <address>
        <city>Valencia</city>
        <zip>46017</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724023</name>
      <address>
        <city>Valladolid</city>
        <zip>47005</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724005</name>
      <address>
        <city>Vigo</city>
        <zip>36312</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 724040</name>
      <address>
        <city>Zaragoza</city>
        <zip>50009</zip>
        <country>Spain</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144002</name>
      <address>
        <city>Colombo 7</city>
        <zip>1000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144004</name>
      <address>
        <city>Colombo 8</city>
        <zip>1000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144003</name>
      <address>
        <city>Colombo</city>
        <zip>1000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144010</name>
      <address>
        <city>Colombo</city>
        <zip>1000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144005</name>
      <address>
        <city>Colombo</city>
        <zip>10250</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144006</name>
      <address>
        <city>Colombo</city>
        <zip>10250</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144001</name>
      <address>
        <city>Colombo</city>
        <zip>7000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144008</name>
      <address>
        <city>Kandy</city>
        <zip>20000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144009</name>
      <address>
        <city>Kurunegala</city>
        <zip>60000</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 144007</name>
      <address>
        <city>Ragama</city>
        <zip>11010</zip>
        <country>Sri Lanka</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752001</name>
      <address>
        <city>Falun</city>
        <zip>791 82</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752016</name>
      <address>
        <city>Göteborg</city>
        <zip>41345</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752011</name>
      <address>
        <city>Halmstad</city>
        <zip>30185</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752006</name>
      <address>
        <city>Karlshamn</city>
        <zip>378 00</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752008</name>
      <address>
        <city>Karlskrona</city>
        <zip>371 85</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752004</name>
      <address>
        <city>Kristianstad</city>
        <zip>29185</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752013</name>
      <address>
        <city>Köping</city>
        <zip>721 51</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752015</name>
      <address>
        <city>Malmö</city>
        <zip>S-20502</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752012</name>
      <address>
        <city>Mölndal</city>
        <zip>43180</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752009</name>
      <address>
        <city>Stockholm</city>
        <zip>11883</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752002</name>
      <address>
        <city>Stockholm</city>
        <zip>14186</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752014</name>
      <address>
        <city>Sundsvall</city>
        <zip>85186</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 752007</name>
      <address>
        <city>Uppsala</city>
        <zip>75237</zip>
        <country>Sweden</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 756005</name>
      <address>
        <city>Basel</city>
        <zip>4031</zip>
        <country>Switzerland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 756003</name>
      <address>
        <city>Geneve</city>
        <zip>1205</zip>
        <country>Switzerland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 756004</name>
      <address>
        <city>Lugano</city>
        <zip>6900</zip>
        <country>Switzerland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 756002</name>
      <address>
        <city>Zürich</city>
        <zip>8091</zip>
        <country>Switzerland</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158003</name>
      <address>
        <city>Changhua</city>
        <zip>500</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158008</name>
      <address>
        <city>Division Of Cardiology</city>
        <zip>833</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158014</name>
      <address>
        <city>Hsinchu</city>
        <zip>30071</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158013</name>
      <address>
        <city>Kaohsiung</city>
        <zip>807</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158004</name>
      <address>
        <city>Taichung</city>
        <zip>402</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158009</name>
      <address>
        <city>Tainan</city>
        <zip>704</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158011</name>
      <address>
        <city>Tainan</city>
        <zip>710</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158005</name>
      <address>
        <city>Taipei</city>
        <zip>104</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158001</name>
      <address>
        <city>Taipei</city>
        <zip>112</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158010</name>
      <address>
        <city>Taipei</city>
        <zip>114</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158007</name>
      <address>
        <city>Taipei</city>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158012</name>
      <address>
        <city>Taoyuan Hsien</city>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 158002</name>
      <address>
        <city>Yunlin</city>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764009</name>
      <address>
        <city>Bangkok-Noi</city>
        <zip>10700</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764001</name>
      <address>
        <city>Bangkok</city>
        <zip>10220</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764011</name>
      <address>
        <city>Bangkok</city>
        <zip>10300</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764007</name>
      <address>
        <city>Bangkok</city>
        <zip>10400</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764012</name>
      <address>
        <city>Bangkok</city>
        <zip>10400</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764005</name>
      <address>
        <city>Hat Yai</city>
        <zip>90110</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764008</name>
      <address>
        <city>Klong Luang</city>
        <zip>12120</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764002</name>
      <address>
        <city>Moung</city>
        <zip>30000</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764003</name>
      <address>
        <city>Muang</city>
        <zip>50200</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764010</name>
      <address>
        <city>Nonthaburi</city>
        <zip>11000</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 764006</name>
      <address>
        <city>Pratumwan</city>
        <zip>10400</zip>
        <country>Thailand</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792007</name>
      <address>
        <city>Adana</city>
        <zip>01339</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792009</name>
      <address>
        <city>Ankara</city>
        <zip>06018</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792006</name>
      <address>
        <city>Bursa</city>
        <zip>16509</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792016</name>
      <address>
        <city>Eskisehir</city>
        <zip>26480</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792014</name>
      <address>
        <city>Istanbul</city>
        <zip>34034</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792005</name>
      <address>
        <city>Istanbul</city>
        <zip>34098</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792011</name>
      <address>
        <city>Istanbul</city>
        <zip>34846</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792013</name>
      <address>
        <city>Istanbul</city>
        <zip>34896</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792004</name>
      <address>
        <city>Izmir</city>
        <zip>35100</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792003</name>
      <address>
        <city>Izmir</city>
        <zip>35340</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792015</name>
      <address>
        <city>Kocaeli</city>
        <zip>41300</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 792010</name>
      <address>
        <city>Mersin</city>
        <zip>33169</zip>
        <country>Turkey</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804015</name>
      <address>
        <city>Chernivtsi</city>
        <zip>58013</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804018</name>
      <address>
        <city>Dnipropetrovsk</city>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804027</name>
      <address>
        <city>Donetsk</city>
        <zip>83114</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804012</name>
      <address>
        <city>Donetsk</city>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804010</name>
      <address>
        <city>Ivano-Frankivsk</city>
        <zip>76018</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804006</name>
      <address>
        <city>Kharkiv</city>
        <zip>61002</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804003</name>
      <address>
        <city>Kharkiv</city>
        <zip>61176</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804009</name>
      <address>
        <city>Kharkiv</city>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804020</name>
      <address>
        <city>Khmelnytskyi</city>
        <zip>29000</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804001</name>
      <address>
        <city>Kiev</city>
        <zip>02091</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804002</name>
      <address>
        <city>Kiev</city>
        <zip>02660</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804011</name>
      <address>
        <city>Kyiv</city>
        <zip>01601</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804014</name>
      <address>
        <city>Kyiv</city>
        <zip>01601</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804025</name>
      <address>
        <city>Kyiv</city>
        <zip>03049</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804034</name>
      <address>
        <city>Kyiv</city>
        <zip>03110</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804036</name>
      <address>
        <city>Kyiv</city>
        <zip>03115</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804016</name>
      <address>
        <city>Kyiv</city>
        <zip>03680</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804030</name>
      <address>
        <city>Kyiv</city>
        <zip>04050</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804028</name>
      <address>
        <city>Lutsk</city>
        <zip>43024</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804033</name>
      <address>
        <city>Lviv</city>
        <zip>79010</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804031</name>
      <address>
        <city>Lviv</city>
        <zip>79059</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804029</name>
      <address>
        <city>Mykolaiv</city>
        <zip>54003</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804013</name>
      <address>
        <city>Odesa</city>
        <zip>65025</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804004</name>
      <address>
        <city>Odessa</city>
        <zip>65014</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804017</name>
      <address>
        <city>Simferopol</city>
        <zip>95026</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804035</name>
      <address>
        <city>Sumy</city>
        <zip>40021</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804007</name>
      <address>
        <city>Uzhgorod</city>
        <zip>88014</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804005</name>
      <address>
        <city>Vinnitsya</city>
        <zip>21100</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804008</name>
      <address>
        <city>Vinnytsia</city>
        <zip>21018</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804026</name>
      <address>
        <city>Zaporizhia</city>
        <zip>69005</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804024</name>
      <address>
        <city>Zhytomyr</city>
        <zip>10002</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 804032</name>
      <address>
        <city>Zhytomyr</city>
        <zip>10002</zip>
        <country>Ukraine</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826018</name>
      <address>
        <city>Basildon</city>
        <zip>SS16 5NL</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826015</name>
      <address>
        <city>Birmingham</city>
        <zip>B18 7QH</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826030</name>
      <address>
        <city>Birmingham</city>
        <zip>B9 5SS</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826038</name>
      <address>
        <city>Bournemouth</city>
        <zip>BH7 7DW</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826025</name>
      <address>
        <city>Bradford</city>
        <zip>BD9 6RJ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826027</name>
      <address>
        <city>Burton On Trent</city>
        <zip>DE13 0RB</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826017</name>
      <address>
        <city>Cardiff</city>
        <zip>CF14 4XW</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826010</name>
      <address>
        <city>Chertsey</city>
        <zip>KT16 0PZ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826012</name>
      <address>
        <city>Chesterfield</city>
        <zip>S44 5BL</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826039</name>
      <address>
        <city>Chichester</city>
        <zip>PO19 4SE</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826024</name>
      <address>
        <city>Cumbria</city>
        <zip>LA14 4LF</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826041</name>
      <address>
        <city>Dudley</city>
        <zip>DY1 2HQ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826021</name>
      <address>
        <city>Harrow</city>
        <zip>HA1 3UJ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826026</name>
      <address>
        <city>High Wycombe</city>
        <zip>HP11 2TT</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826028</name>
      <address>
        <city>Hull</city>
        <zip>HU16 5JQ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826034</name>
      <address>
        <city>London</city>
        <zip>E2 9JX</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826004</name>
      <address>
        <city>Manchester</city>
        <zip>M13 9WL</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826011</name>
      <address>
        <city>Newcastle Upon Tyne</city>
        <zip>NE7 7DN</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826036</name>
      <address>
        <city>Northampton</city>
        <zip>NN1 5BD</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826019</name>
      <address>
        <city>Peterborough</city>
        <zip>PE3 9GZ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826020</name>
      <address>
        <city>Plymouth</city>
        <zip>PL6 8DH</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826040</name>
      <address>
        <city>Portadown</city>
        <zip>BT63 5QQ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826016</name>
      <address>
        <city>Portsmouth</city>
        <zip>PO6 3LY</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826014</name>
      <address>
        <city>Redhill</city>
        <zip>RH1 5RH</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826007</name>
      <address>
        <city>Rhyl</city>
        <zip>LL18 5UJ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826001</name>
      <address>
        <city>Romford</city>
        <zip>RM7 0AG</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826009</name>
      <address>
        <city>Rotherham</city>
        <zip>S60 2UD</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826002</name>
      <address>
        <city>Sheffield</city>
        <zip>S10 2RX</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826032</name>
      <address>
        <city>South Shields</city>
        <zip>NE34 0PL</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826013</name>
      <address>
        <city>St Leonards</city>
        <zip>TN37 7RD</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826005</name>
      <address>
        <city>Stoke-On-Trent</city>
        <zip>ST4 6QG</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826031</name>
      <address>
        <city>Sunderland</city>
        <zip>SR4 7TP</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826022</name>
      <address>
        <city>Truro</city>
        <zip>TR1 3LJ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826035</name>
      <address>
        <city>Wigan</city>
        <zip>WN1 2NN</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Investigational Site Number 826003</name>
      <address>
        <city>Worcester</city>
        <zip>WR5 1DD</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Argentina</country>
    <country>Australia</country>
    <country>Austria</country>
    <country>Belgium</country>
    <country>Bosnia and Herzegovina</country>
    <country>Brazil</country>
    <country>Bulgaria</country>
    <country>Canada</country>
    <country>Chile</country>
    <country>China</country>
    <country>Colombia</country>
    <country>Croatia</country>
    <country>Czechia</country>
    <country>Denmark</country>
    <country>Estonia</country>
    <country>Finland</country>
    <country>France</country>
    <country>Georgia</country>
    <country>Germany</country>
    <country>Greece</country>
    <country>Guatemala</country>
    <country>Hong Kong</country>
    <country>Hungary</country>
    <country>India</country>
    <country>Israel</country>
    <country>Italy</country>
    <country>Japan</country>
    <country>Korea, Republic of</country>
    <country>Latvia</country>
    <country>Lithuania</country>
    <country>Macedonia, The Former Yugoslav Republic of</country>
    <country>Malaysia</country>
    <country>Mexico</country>
    <country>Netherlands</country>
    <country>New Zealand</country>
    <country>Norway</country>
    <country>Peru</country>
    <country>Philippines</country>
    <country>Poland</country>
    <country>Portugal</country>
    <country>Romania</country>
    <country>Russian Federation</country>
    <country>Serbia</country>
    <country>Singapore</country>
    <country>Slovakia</country>
    <country>Slovenia</country>
    <country>South Africa</country>
    <country>Spain</country>
    <country>Sri Lanka</country>
    <country>Sweden</country>
    <country>Switzerland</country>
    <country>Taiwan</country>
    <country>Thailand</country>
    <country>Turkey</country>
    <country>Ukraine</country>
    <country>United Kingdom</country>
    <country>United States</country>
  </location_countries>
  <removed_countries>
    <country>Czech Republic</country>
  </removed_countries>
  <verification_date>March 2019</verification_date>
  <study_first_submitted>August 8, 2012</study_first_submitted>
  <study_first_submitted_qc>August 10, 2012</study_first_submitted_qc>
  <study_first_posted type="Estimate">August 13, 2012</study_first_posted>
  <results_first_submitted>January 21, 2019</results_first_submitted>
  <results_first_submitted_qc>March 15, 2019</results_first_submitted_qc>
  <results_first_posted type="Actual">March 18, 2019</results_first_posted>
  <last_update_submitted>March 15, 2019</last_update_submitted>
  <last_update_submitted_qc>March 15, 2019</last_update_submitted_qc>
  <last_update_posted type="Actual">March 18, 2019</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Cardiovascular Diseases</mesh_term>
    <mesh_term>Acute Coronary Syndrome</mesh_term>
    <mesh_term>Atherosclerosis</mesh_term>
  </condition_browse>
  <intervention_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Alirocumab</mesh_term>
  </intervention_browse>
  <provided_document_section>
    <provided_document>
      <document_type>Study Protocol</document_type>
      <document_has_protocol>Yes</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>No</document_has_sap>
      <document_date>February 25, 2016</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/02/NCT01663402/Prot_000.pdf</document_url>
    </provided_document>
    <provided_document>
      <document_type>Statistical Analysis Plan</document_type>
      <document_has_protocol>No</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>Yes</document_has_sap>
      <document_date>October 11, 2017</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/02/NCT01663402/SAP_001.pdf</document_url>
    </provided_document>
  </provided_document_section>

  <clinical_results>

    <participant_flow>
      <recruitment_details>The study was conducted at 1387 sites in 57 countries. Of these, 1328 active sites randomized at least 1 participant. Overall, 35,437 participants were screened between 11 October 2012 and 17 Jan 2017; of whom 16,513 were screen failures. Screen failures were mainly due to exclusion criteria met.</recruitment_details>
      <pre_assignment_details>Randomization was stratified according to country. Assignment to treatment arms was done centrally using an Interactive Voice/Web Response System in a 1:1 ratio (alirocumab: placebo), with permuted-block randomization.</pre_assignment_details>
      <group_list>
        <group group_id="P1">
          <title>Placebo</title>
          <description>Placebo (for alirocumab) SC injection every 2 weeks (Q2W) added to stable Lipid-Modifying Therapy (LMT) for up to 64 months.</description>
        </group>
        <group group_id="P2">
          <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
          <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
        </group>
      </group_list>
      <period_list>
        <period>
          <title>Overall Study</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="9462"/>
                <participants group_id="P2" count="9462"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>Treated</title>
              <participants_list>
                <participants group_id="P1" count="9443"/>
                <participants group_id="P2" count="9451"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="7947"/>
                <participants group_id="P2" count="7378"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="1515"/>
                <participants group_id="P2" count="2084"/>
              </participants_list>
            </milestone>
          </milestone_list>
          <drop_withdraw_reason_list>
            <drop_withdraw_reason>
              <title>Randomized but not treated</title>
              <participants_list>
                <participants group_id="P1" count="19"/>
                <participants group_id="P2" count="11"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Adverse Event</title>
              <participants_list>
                <participants group_id="P1" count="347"/>
                <participants group_id="P2" count="362"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Two consecutive LDL-C &lt;15 mg/dL</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="730"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Poor compliance to protocol</title>
              <participants_list>
                <participants group_id="P1" count="529"/>
                <participants group_id="P2" count="454"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Physician Decision</title>
              <participants_list>
                <participants group_id="P1" count="77"/>
                <participants group_id="P2" count="62"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Site terminated by sponsor</title>
              <participants_list>
                <participants group_id="P1" count="1"/>
                <participants group_id="P2" count="3"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Participant moved</title>
              <participants_list>
                <participants group_id="P1" count="139"/>
                <participants group_id="P2" count="104"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Withdrawal by Subject</title>
              <participants_list>
                <participants group_id="P1" count="118"/>
                <participants group_id="P2" count="91"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Related to study drug administration</title>
              <participants_list>
                <participants group_id="P1" count="96"/>
                <participants group_id="P2" count="105"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Lost to Follow-up</title>
              <participants_list>
                <participants group_id="P1" count="17"/>
                <participants group_id="P2" count="15"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Other than specified above</title>
              <participants_list>
                <participants group_id="P1" count="172"/>
                <participants group_id="P2" count="147"/>
              </participants_list>
            </drop_withdraw_reason>
          </drop_withdraw_reason_list>
        </period>
      </period_list>
    </participant_flow>

    <baseline>
      <population>Baseline population included all randomized participants.</population>
      <group_list>
        <group group_id="B1">
          <title>Placebo</title>
          <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
        </group>
        <group group_id="B2">
          <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
          <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
        </group>
        <group group_id="B3">
          <title>Total</title>
          <description>Total of all reporting groups</description>
        </group>
      </group_list>
      <analyzed_list>
        <analyzed>
          <units>Participants</units>
          <scope>Overall</scope>
          <count_list>
            <count group_id="B1" value="9462"/>
            <count group_id="B2" value="9462"/>
            <count group_id="B3" value="18924"/>
          </count_list>
        </analyzed>
      </analyzed_list>
      <measure_list>
        <measure>
          <title>Age</title>
          <units>years</units>
          <param>Mean</param>
          <dispersion>Standard Deviation</dispersion>
          <class_list>
            <class>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9462"/>
                    <count group_id="B2" value="9462"/>
                    <count group_id="B3" value="18924"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="58.6" spread="9.4"/>
                    <measurement group_id="B2" value="58.5" spread="9.3"/>
                    <measurement group_id="B3" value="58.6" spread="9.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Sex: Female, Male</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9462"/>
                    <count group_id="B2" value="9462"/>
                    <count group_id="B3" value="18924"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Female</title>
                  <measurement_list>
                    <measurement group_id="B1" value="2372"/>
                    <measurement group_id="B2" value="2390"/>
                    <measurement group_id="B3" value="4762"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Male</title>
                  <measurement_list>
                    <measurement group_id="B1" value="7090"/>
                    <measurement group_id="B2" value="7072"/>
                    <measurement group_id="B3" value="14162"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Ethnicity (NIH/OMB)</title>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9462"/>
                    <count group_id="B2" value="9462"/>
                    <count group_id="B3" value="18924"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="1555"/>
                    <measurement group_id="B2" value="1581"/>
                    <measurement group_id="B3" value="3136"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Not Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="7721"/>
                    <measurement group_id="B2" value="7700"/>
                    <measurement group_id="B3" value="15421"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Unknown or Not Reported</title>
                  <measurement_list>
                    <measurement group_id="B1" value="186"/>
                    <measurement group_id="B2" value="181"/>
                    <measurement group_id="B3" value="367"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Race/Ethnicity, Customized</title>
          <population>Here, 'number analyzed' signifies participants with available for specified measure.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <title>White</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9460"/>
                    <count group_id="B2" value="9461"/>
                    <count group_id="B3" value="18921"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="7524"/>
                    <measurement group_id="B2" value="7500"/>
                    <measurement group_id="B3" value="15024"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Black or African American</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9460"/>
                    <count group_id="B2" value="9461"/>
                    <count group_id="B3" value="18921"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="238"/>
                    <measurement group_id="B2" value="235"/>
                    <measurement group_id="B3" value="473"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Asian</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9460"/>
                    <count group_id="B2" value="9461"/>
                    <count group_id="B3" value="18921"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="1247"/>
                    <measurement group_id="B2" value="1251"/>
                    <measurement group_id="B3" value="2498"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Other</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9460"/>
                    <count group_id="B2" value="9461"/>
                    <count group_id="B3" value="18921"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="449"/>
                    <measurement group_id="B2" value="469"/>
                    <measurement group_id="B3" value="918"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Unknown</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="9460"/>
                    <count group_id="B2" value="9461"/>
                    <count group_id="B3" value="18921"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="B1" value="2"/>
                    <measurement group_id="B2" value="6"/>
                    <measurement group_id="B3" value="8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </measure_list>
    </baseline>

    <outcome_list>
      <outcome>
        <type>Primary</type>
        <title>Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>All MACE positively adjudicated by Clinical Events Committee (CEC) in a blinded fashion, were used in the analysis of the composite cardiovascular (CV) outcome measure comprised of Coronary Heart Disease (CHD) death, non-fatal Myocardial Infarction (MI), fatal and non-fatal ischemic stroke (IS), or unstable angina (UA) requiring hospitalization. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of MACE over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>Intent-to-treat (ITT) population included all randomized participants.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>All MACE positively adjudicated by Clinical Events Committee (CEC) in a blinded fashion, were used in the analysis of the composite cardiovascular (CV) outcome measure comprised of Coronary Heart Disease (CHD) death, non-fatal Myocardial Infarction (MI), fatal and non-fatal ischemic stroke (IS), or unstable angina (UA) requiring hospitalization. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of MACE over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
          <population>Intent-to-treat (ITT) population included all randomized participants.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="11.1"/>
                    <measurement group_id="O2" value="9.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region (North America, South America, Western Europe, Eastern Europe, Asia, Rest of the world).</groups_desc>
            <non_inferiority_type>Superiority</non_inferiority_type>
            <p_value>0.0003</p_value>
            <p_value_desc>Threshold for statistical significance at 0.0498 level.</p_value_desc>
            <method>Log Rank</method>
            <param_type>Hazard Ratio (HR)</param_type>
            <param_value>0.85</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.78</ci_lower_limit>
            <ci_upper_limit>0.93</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>All CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death, non-fatal non-fatal MI, UA requiring hospitalization, or ischemia-driven coronary revascularization procedure. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>All CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death, non-fatal non-fatal MI, UA requiring hospitalization, or ischemia-driven coronary revascularization procedure. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="14.3"/>
                    <measurement group_id="O2" value="12.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region(North America,South America,Western Europe,Eastern Europe,Asia, Rest of the world).A hierarchical testing approach was used to control the overall type-I error at 0.0249 one-sided alpha level(0.0498 two-sided).Testing was then performed sequentially in the order endpoints were reported.Hierarchical testing sequence continued only if the previous endpoint was statistically significant.</groups_desc>
            <non_inferiority_type>Superiority</non_inferiority_type>
            <p_value>0.0013</p_value>
            <p_value_desc>Threshold for statistical significance at 0.0498 level.</p_value_desc>
            <method>Log Rank</method>
            <param_type>Hazard Ratio (HR)</param_type>
            <param_value>0.88</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.81</ci_lower_limit>
            <ci_upper_limit>0.95</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>All Major CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death and non-fatal MI. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any major CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>All Major CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death and non-fatal MI. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any major CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="9.5"/>
                    <measurement group_id="O2" value="8.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region (North America, South America, Western Europe, Eastern Europe, Asia, Rest of the world). Testing was performed according to the hierarchical testing procedure (continued only if the previous endpoint was statistically significant).</groups_desc>
            <non_inferiority_type>Superiority</non_inferiority_type>
            <p_value>0.0060</p_value>
            <p_value_desc>Threshold for statistical significance at 0.0498 level.</p_value_desc>
            <method>Log Rank</method>
            <param_type>Hazard Ratio (HR)</param_type>
            <param_value>0.88</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.80</ci_lower_limit>
            <ci_upper_limit>0.96</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>All CV events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CV endpoint comprised of any non-fatal CHD event, any CV death and non-fatal IS. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CV event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>All CV events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CV endpoint comprised of any non-fatal CHD event, any CV death and non-fatal IS. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CV event over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="15.6"/>
                    <measurement group_id="O2" value="13.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region (North America, South America, Western Europe, Eastern Europe, Asia, Rest of the world). Testing according to the hierarchical testing procedure (continued only if the previous endpoint was statistically significant).</groups_desc>
            <non_inferiority_type>Superiority</non_inferiority_type>
            <p_value>0.0003</p_value>
            <p_value_desc>Threshold for statistical significance at 0.0498 level.</p_value_desc>
            <method>Log Rank</method>
            <param_type>Hazard Ratio (HR)</param_type>
            <param_value>0.87</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.81</ci_lower_limit>
            <ci_upper_limit>0.94</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>All-cause mortality, non-fatal MI and non-fatal IS positively adjudicated by CEC in a blinded fashion, were used in the analysis of this endpoint. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of all-cause mortality, non-fatal MI and non-fatal IS over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>All-cause mortality, non-fatal MI and non-fatal IS positively adjudicated by CEC in a blinded fashion, were used in the analysis of this endpoint. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of all-cause mortality, non-fatal MI and non-fatal IS over time. Percentage of observed participants with outcome measure events during the study were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="11.9"/>
                    <measurement group_id="O2" value="10.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region (North America, South America, Western Europe, Eastern Europe, Asia, Rest of the world). Testing according to the hierarchical testing procedure (continued only if the previous endpoint was statistically significant).</groups_desc>
            <non_inferiority_type>Superiority</non_inferiority_type>
            <p_value>0.0003</p_value>
            <p_value_desc>Threshold for statistical significance at 0.0498 level.</p_value_desc>
            <method>Log Rank</method>
            <param_type>Hazard Ratio (HR)</param_type>
            <param_value>0.86</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.79</ci_lower_limit>
            <ci_upper_limit>0.93</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CHD death over time. Percentage of observed participants with CHD death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CHD death over time. Percentage of observed participants with CHD death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.3"/>
                    <measurement group_id="O2" value="2.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <groups_desc>Analysis was performed using Cox proportional hazard model and log rank test stratified on geographical region (North America, South America, Western Europe, Eastern Europe, Asia, Rest of the world). Testing according to the hierarchical testing procedure (continued only if the previous endpoint was statistically significant).</groups_desc>
            <non_inferiority_type>Superiority</non_inferiority_type>
            <p_value>0.3824</p_value>
            <p_value_desc>Threshold for statistical significance at 0.0498 level.</p_value_desc>
            <method>Log Rank</method>
            <param_type>Hazard Ratio (HR)</param_type>
            <param_value>0.92</param_value>
            <ci_percent>95</ci_percent>
            <ci_n_sides>2-Sided</ci_n_sides>
            <ci_lower_limit>0.76</ci_lower_limit>
            <ci_upper_limit>1.11</ci_upper_limit>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CV death over time. Percentage of observed participants with CV death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CV death over time. Percentage of observed participants with CV death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.9"/>
                    <measurement group_id="O2" value="2.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the all-cause death over time. Percentage of observed participants with all-cause death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the all-cause death over time. Percentage of observed participants with all-cause death (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.1"/>
                    <measurement group_id="O2" value="3.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any non-fatal MI over time. Percentage of observed participants with any non-fatal MI (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any non-fatal MI over time. Percentage of observed participants with any non-fatal MI (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.6"/>
                    <measurement group_id="O2" value="6.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of fatal or any non-fatal IS over time. Percentage of observed participants with fatal or any non-fatal IS (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of fatal or any non-fatal IS over time. Percentage of observed participants with fatal or any non-fatal IS (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.6"/>
                    <measurement group_id="O2" value="1.2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any UA requiring hospitalization over time. Percentage of observed participants with any UA requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any UA requiring hospitalization over time. Percentage of observed participants with any UA requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0.6"/>
                    <measurement group_id="O2" value="0.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any ischemia-driven coronary revascularization procedure over time. Percentage of observed participants with any ischemia-driven coronary revascularization procedure (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any ischemia-driven coronary revascularization procedure over time. Percentage of observed participants with any ischemia-driven coronary revascularization procedure (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="8.8"/>
                    <measurement group_id="O2" value="7.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
        <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHF requiring hospitalization over time. Percentage of observed participants with any CHF requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.</description>
        <time_frame>From randomization up to 64 months</time_frame>
        <population>ITT Population.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study</title>
          <description>Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHF requiring hospitalization over time. Percentage of observed participants with any CHF requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.</description>
          <population>ITT Population.</population>
          <units>percentage of participants</units>
          <param>Number</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.9"/>
                    <measurement group_id="O2" value="1.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Other Pre-specified</type>
        <title>Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis</title>
        <description>Adjusted means and standard errors at Month 4, 12 and 48 from multiple imputation approach (to account for missing data) followed by analyses of covariance (ANCOVA) model with the fixed categorical effect of treatment group and the continuous fixed covariate of baseline LDL-C value, including all available post-baseline data from Month 1 up to Month 48 regardless of status on- or off-treatment.</description>
        <time_frame>Baseline, Months 4, 12 and 48</time_frame>
        <population>ITT Population. Here, 'number analyzed' corresponds to the number of participants with the parameter measured and baseline measure available for each time-point. A multiple approach was used to account for participants with missing data.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis</title>
          <description>Adjusted means and standard errors at Month 4, 12 and 48 from multiple imputation approach (to account for missing data) followed by analyses of covariance (ANCOVA) model with the fixed categorical effect of treatment group and the continuous fixed covariate of baseline LDL-C value, including all available post-baseline data from Month 1 up to Month 48 regardless of status on- or off-treatment.</description>
          <population>ITT Population. Here, 'number analyzed' corresponds to the number of participants with the parameter measured and baseline measure available for each time-point. A multiple approach was used to account for participants with missing data.</population>
          <units>Percent change</units>
          <param>Least Squares Mean</param>
          <dispersion>Standard Error</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9462"/>
                <count group_id="O2" value="9462"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Month 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="8750"/>
                    <count group_id="O2" value="8602"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.4" spread="0.3"/>
                    <measurement group_id="O2" value="-55.8" spread="0.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Month 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="8397"/>
                    <count group_id="O2" value="8336"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="8.0" spread="0.4"/>
                    <measurement group_id="O2" value="-45.7" spread="0.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Month 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="790"/>
                    <count group_id="O2" value="812"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="16.4" spread="1.8"/>
                    <measurement group_id="O2" value="-23.5" spread="1.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Other Pre-specified</type>
        <title>Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: On-Treatment Analysis</title>
        <description>Adjusted Least-squares (LS) means and standard errors at Month 4, 12 and 48 were obtained from a mixed-effect model with repeated measures (MMRM) including available post-baseline on-treatment data from Month 1 up to Month 48 (i.e. up to 21 days after last injection).</description>
        <time_frame>Baseline, Months 4, 12 and 48</time_frame>
        <population>Randomized and treated population. Here, 'number analyzed' signifies participants evaluable for this outcome measure at specified time points.</population>
        <group_list>
          <group group_id="O1">
            <title>Placebo</title>
            <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
          </group>
          <group group_id="O2">
            <title>Alirocumab 75 mg Q2W/Up to 150 mg Q2W</title>
            <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
          </group>
        </group_list>
        <measure>
          <title>Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: On-Treatment Analysis</title>
          <description>Adjusted Least-squares (LS) means and standard errors at Month 4, 12 and 48 were obtained from a mixed-effect model with repeated measures (MMRM) including available post-baseline on-treatment data from Month 1 up to Month 48 (i.e. up to 21 days after last injection).</description>
          <population>Randomized and treated population. Here, 'number analyzed' signifies participants evaluable for this outcome measure at specified time points.</population>
          <units>Percent change</units>
          <param>Least Squares Mean</param>
          <dispersion>Standard Error</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="9443"/>
                <count group_id="O2" value="9451"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Month 4</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="8647"/>
                    <count group_id="O2" value="8486"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.4" spread="0.3"/>
                    <measurement group_id="O2" value="-58.3" spread="0.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Month 12</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="8183"/>
                    <count group_id="O2" value="7727"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="8.2" spread="0.4"/>
                    <measurement group_id="O2" value="-52.8" spread="0.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Month 48</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="726"/>
                    <count group_id="O2" value="647"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="14.6" spread="1.0"/>
                    <measurement group_id="O2" value="-40.1" spread="1.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
    </outcome_list>

    <reported_events>
      <time_frame>All Adverse Events (AEs) were collected from signature of the informed consent form until the end of study (Month 64) regardless of seriousness or relationship to Investigational Medicinal Product (IMP).</time_frame>
      <desc>Reported AEs are treatment-emergent AEs that is AEs that developed/worsened during the 'treatment-emergent period' (the time from the first dose of study drug up to the last dose of study drug +70 days). Safety population included randomized participants who actually received at least 1 dose or part of a dose of the double-blind IMP injection.</desc>
      <group_list>
        <group group_id="E1">
          <title>Placebo</title>
          <description>Placebo (for alirocumab) SC injection Q2W added to stable LMT for up to 64 months.</description>
        </group>
        <group group_id="E2">
          <title>Alirocumab</title>
          <description>Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when LDL-C levels &gt;=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were &lt;25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were &lt;15 mg/dL (0.39 mmol/L).</description>
        </group>
      </group_list>
      <serious_events>
        <default_vocab>MedDra 20.1</default_vocab>
        <default_assessment>Systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, all-cause mortality</sub_title>
                <counts group_id="E1" subjects_affected="278" subjects_at_risk="9443"/>
                <counts group_id="E2" subjects_affected="238" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Total, serious adverse events</sub_title>
                <counts group_id="E1" subjects_affected="2350" subjects_at_risk="9443"/>
                <counts group_id="E2" subjects_affected="2202" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Blood and lymphatic system disorders</title>
            <event_list>
              <event>
                <sub_title>Anaemia</sub_title>
                <counts group_id="E1" events="15" subjects_affected="15" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaemia Of Chronic Disease</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaemia Of Malignant Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaemia Vitamin B12 Deficiency</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Autoimmune Haemolytic Anaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coagulopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Disseminated Intravascular Coagulation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Febrile Neutropenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemolytic Anaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhagic Anaemia</sub_title>
                <counts group_id="E1" events="18" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="15" subjects_affected="14" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhagic Diathesis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypochromic Anaemia</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Iron Deficiency Anaemia</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Leukocytosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Leukopenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lymphadenitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lymphadenopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Microcytic Anaemia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nephrogenic Anaemia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Normochromic Normocytic Anaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Normocytic Anaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thrombocytopenia</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thrombotic Thrombocytopenic Purpura</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Cardiac disorders</title>
            <event_list>
              <event>
                <sub_title>Acute Coronary Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Left Ventricular Failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Myocardial Infarction</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adams-Stokes Syndrome</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Angina Pectoris</sub_title>
                <counts group_id="E1" events="148" subjects_affected="133" subjects_at_risk="9443"/>
                <counts group_id="E2" events="136" subjects_affected="113" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Angina Unstable</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Valve Disease Mixed</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Valve Incompetence</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Valve Sclerosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Valve Stenosis</sub_title>
                <counts group_id="E1" events="17" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arrhythmia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arrhythmia Supraventricular</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arteriosclerosis Coronary Artery</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arteriospasm Coronary</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrial Fibrillation</sub_title>
                <counts group_id="E1" events="110" subjects_affected="98" subjects_at_risk="9443"/>
                <counts group_id="E2" events="103" subjects_affected="82" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrial Flutter</sub_title>
                <counts group_id="E1" events="14" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="16" subjects_affected="14" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrial Tachycardia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrioventricular Block</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrioventricular Block Complete</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrioventricular Block First Degree</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atrioventricular Block Second Degree</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bradycardia</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bundle Branch Block Left</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bundle Branch Block Right</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Aneurysm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Arrest</sub_title>
                <counts group_id="E1" events="10" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Failure</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Failure Acute</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Failure Chronic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Failure Congestive</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Flutter</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Perforation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Tamponade</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardio-Respiratory Arrest</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiogenic Shock</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiomyopathy</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chordae Tendinae Rupture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Conduction Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Congestive Cardiomyopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coronary Artery Disease</sub_title>
                <counts group_id="E1" events="20" subjects_affected="20" subjects_at_risk="9443"/>
                <counts group_id="E2" events="26" subjects_affected="25" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coronary Artery Dissection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coronary Artery Occlusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coronary Artery Stenosis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diastolic Dysfunction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Extrasystoles</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intracardiac Mass</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intracardiac Thrombus</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ischaemic Cardiomyopathy</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ischaemic Mitral Regurgitation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Left Ventricular Dysfunction</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Low Cardiac Output Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Microvascular Coronary Artery Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mitral Valve Incompetence</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mitral Valve Prolapse</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myocardial Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myocardial Infarction</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myocardial Ischaemia</sub_title>
                <counts group_id="E1" events="13" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myocardial Rupture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myocarditis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nodal Arrhythmia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nodal Rhythm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Palpitations</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Papillary Muscle Rupture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pericardial Effusion</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pericardial Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pericarditis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pleuropericarditis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prinzmetal Angina</sub_title>
                <counts group_id="E1" events="3" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulseless Electrical Activity</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rhythm Idioventricular</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinus Arrest</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinus Arrhythmia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinus Bradycardia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinus Node Dysfunction</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="13" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinus Tachycardia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Stress Cardiomyopathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Supraventricular Extrasystoles</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Supraventricular Tachycardia</sub_title>
                <counts group_id="E1" events="16" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Systolic Dysfunction</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tachyarrhythmia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tachycardia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tricuspid Valve Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ventricular Arrhythmia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ventricular Extrasystoles</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ventricular Fibrillation</sub_title>
                <counts group_id="E1" events="17" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ventricular Hypokinesia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ventricular Tachycardia</sub_title>
                <counts group_id="E1" events="33" subjects_affected="29" subjects_at_risk="9443"/>
                <counts group_id="E2" events="28" subjects_affected="24" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Congenital, familial and genetic disorders</title>
            <event_list>
              <event>
                <sub_title>Atrial Septal Defect</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bicuspid Aortic Valve</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchogenic Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermoid Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Arteriovenous Malformation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhagic Arteriovenous Malformation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hereditary Optic Atrophy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinocerebellar Ataxia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thyroglossal Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Von Hippel-Lindau Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Ear and labyrinth disorders</title>
            <event_list>
              <event>
                <sub_title>Acute Vestibular Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Deafness Neurosensory</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoacusis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sudden Hearing Loss</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tinnitus</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tympanic Membrane Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tympanic Membrane Perforation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertigo</sub_title>
                <counts group_id="E1" events="12" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertigo Labyrinthine</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertigo Positional</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Endocrine disorders</title>
            <event_list>
              <event>
                <sub_title>Adrenal Insufficiency</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adrenocortical Insufficiency Acute</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adrenocorticotropic Hormone Deficiency</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Autoimmune Hypothyroidism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Basedow's Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Goitre</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperthyroidism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypothyroidism</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Inappropriate Antidiuretic Hormone Secretion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pituitary Cyst</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thyroid Mass</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Toxic Goitre</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Toxic Nodular Goitre</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Eye disorders</title>
            <event_list>
              <event>
                <sub_title>Amaurosis Fugax</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blepharochalasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cataract</sub_title>
                <counts group_id="E1" events="13" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cataract Diabetic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cataract Subcapsular</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Conjunctival Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Corneal Degeneration</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Retinopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Eye Muscle Entrapment</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Glaucoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Macular Degeneration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ocular Myasthenia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Optic Ischaemic Neuropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Posterior Capsule Opacification</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Retinal Artery Embolism</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Retinal Artery Occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Retinal Detachment</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Retinal Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Retinal Vein Occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ulcerative Keratitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Visual Acuity Reduced</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vitreous Detachment</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vitreous Haemorrhage</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Gastrointestinal disorders</title>
            <event_list>
              <event>
                <sub_title>Abdominal Adhesions</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Distension</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Hernia</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Incarcerated Hernia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Pain</sub_title>
                <counts group_id="E1" events="12" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Pain Upper</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Strangulated Hernia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Wall Haematoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Alcoholic Pancreatitis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Fissure</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Fistula</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Incontinence</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Polyp</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aphthous Ulcer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Appendix Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ascites</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Barrett's Oesophagus</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bile Acid Malabsorption</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breath Odour</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Gastritis</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colitis</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colitis Ischaemic</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colitis Microscopic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colitis Ulcerative</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Constipation</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Crohn's Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dental Caries</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Gastroparesis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diarrhoea</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diarrhoea Haemorrhagic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dieulafoy's Vascular Malformation</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diverticular Perforation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diverticulum</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diverticulum Intestinal</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diverticulum Intestinal Haemorrhagic</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Duodenal Obstruction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Duodenal Ulcer</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Duodenal Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="10" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Duodenal Vascular Ectasia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Duodenitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Duodenitis Haemorrhagic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dyspepsia</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dysphagia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enteritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterocolitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterocolitis Haemorrhagic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erosive Duodenitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erosive Oesophagitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Faecaloma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Femoral Hernia, Obstructive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fistula Of Small Intestine</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Food Poisoning</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Functional Gastrointestinal Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Polyps</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Ulcer</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="12" subjects_affected="11" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="14" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Ulcer, Obstructive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastritis</sub_title>
                <counts group_id="E1" events="19" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastritis Erosive</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastritis Haemorrhagic</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastroduodenitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastroduodenitis Haemorrhagic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Angiectasia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Angiodysplasia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Angiodysplasia Haemorrhagic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Haemorrhage</sub_title>
                <counts group_id="E1" events="13" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="12" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Inflammation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Mucosal Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Pain</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Polyp Haemorrhage</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Ulcer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrooesophageal Reflux Disease</sub_title>
                <counts group_id="E1" events="20" subjects_affected="19" subjects_at_risk="9443"/>
                <counts group_id="E2" events="24" subjects_affected="21" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gingival Bleeding</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haematemesis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haematochezia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhagic Erosive Gastritis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhoidal Haemorrhage</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhoids</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hiatus Hernia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hiatus Hernia Strangulated</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ileal Perforation</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ileus</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ileus Paralytic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Incarcerated Hiatus Hernia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Incarcerated Inguinal Hernia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Incarcerated Umbilical Hernia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Inguinal Hernia</sub_title>
                <counts group_id="E1" events="15" subjects_affected="15" subjects_at_risk="9443"/>
                <counts group_id="E2" events="29" subjects_affected="29" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intestinal Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intestinal Infarction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intestinal Ischaemia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intestinal Obstruction</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intestinal Perforation</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Irritable Bowel Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Large Intestinal Obstruction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Large Intestinal Ulcer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Large Intestine Perforation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Large Intestine Polyp</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lower Gastrointestinal Haemorrhage</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lumbar Hernia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mallory-Weiss Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Megacolon</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Melaena</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mesenteric Artery Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mesenteric Panniculitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nausea</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Obstruction Gastric</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Obstructive Pancreatitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Odynophagia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oedematous Pancreatitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Achalasia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Rupture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Spasm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Stenosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Varices Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophagitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophagitis Haemorrhagic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Pseudocyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatitis</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatitis Acute</sub_title>
                <counts group_id="E1" events="16" subjects_affected="16" subjects_at_risk="9443"/>
                <counts group_id="E2" events="15" subjects_affected="15" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatitis Chronic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatitis Necrotising</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peptic Ulcer</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peptic Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Periodontal Disease</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peritoneal Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peritoneal Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Haemorrhage</sub_title>
                <counts group_id="E1" events="6" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Prolapse</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Retroperitoneal Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Salivary Duct Obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Salivary Gland Calculus</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Small Intestinal Obstruction</sub_title>
                <counts group_id="E1" events="6" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Small Intestinal Perforation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Small Intestinal Ulcer Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Swollen Tongue</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tongue Haematoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Toothache</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Umbilical Hernia</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Umbilical Hernia, Obstructive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Upper Gastrointestinal Haemorrhage</sub_title>
                <counts group_id="E1" events="8" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Varices Oesophageal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vomiting</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>General disorders</title>
            <event_list>
              <event>
                <sub_title>Asthenia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chest Discomfort</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chest Pain</sub_title>
                <counts group_id="E1" events="32" subjects_affected="29" subjects_at_risk="9443"/>
                <counts group_id="E2" events="27" subjects_affected="25" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Death</sub_title>
                <counts group_id="E1" events="33" subjects_affected="33" subjects_at_risk="9443"/>
                <counts group_id="E2" events="25" subjects_affected="25" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Device Related Thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Exercise Tolerance Decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Facial Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fatigue</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gait Disturbance</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>General Physical Health Deterioration</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Granuloma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Impaired Healing</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Implant Site Haematoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Implant Site Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Incarcerated Hernia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Influenza Like Illness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Injection Site Reaction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malaise</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Medical Device Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Medical Device Site Dermatitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Medical Device Site Joint Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Medical Device Site Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Multiple Organ Dysfunction Syndrome</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Cardiac Chest Pain</sub_title>
                <counts group_id="E1" events="256" subjects_affected="222" subjects_at_risk="9443"/>
                <counts group_id="E2" events="264" subjects_affected="219" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oedema Peripheral</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pacemaker Generated Arrhythmia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pelvic Mass</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Swelling</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pyrexia</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Soft Tissue Inflammation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Strangulated Hernia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sudden Cardiac Death</sub_title>
                <counts group_id="E1" events="42" subjects_affected="42" subjects_at_risk="9443"/>
                <counts group_id="E2" events="36" subjects_affected="36" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sudden Death</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="14" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Systemic Inflammatory Response Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Stent Restenosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Stent Thrombosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vessel Puncture Site Haematoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vessel Puncture Site Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Hepatobiliary disorders</title>
            <event_list>
              <event>
                <sub_title>Acute Hepatic Failure</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ampulla Of Vater Stenosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bile Duct Stenosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bile Duct Stone</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Biliary Colic</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Biliary Dyskinesia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Biliary Tract Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholangitis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholangitis Acute</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholangitis Sclerosing</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholecystitis</sub_title>
                <counts group_id="E1" events="14" subjects_affected="14" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholecystitis Acute</sub_title>
                <counts group_id="E1" events="14" subjects_affected="14" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholecystitis Chronic</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholelithiasis</sub_title>
                <counts group_id="E1" events="35" subjects_affected="35" subjects_at_risk="9443"/>
                <counts group_id="E2" events="25" subjects_affected="25" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholestasis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Hepatitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cirrhosis Alcoholic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Drug-Induced Liver Injury</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="15" subjects_affected="15" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gallbladder Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gallbladder Necrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gallbladder Perforation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Cirrhosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Congestion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Failure</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Function Abnormal</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Lesion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Necrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Steatosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Vein Dilatation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatitis Acute</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatitis Alcoholic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatitis Chronic Active</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatitis Toxic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatocellular Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperplastic Cholecystopathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ischaemic Hepatitis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Jaundice Cholestatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Liver Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Liver Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Steatohepatitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Immune system disorders</title>
            <event_list>
              <event>
                <sub_title>Allergy To Arthropod Bite</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Allergy To Arthropod Sting</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaphylactic Reaction</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaphylactic Shock</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Contrast Media Allergy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Drug Hypersensitivity</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypersensitivity</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Iodine Allergy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Abdominal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Sepsis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Wall Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abscess Limb</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Endocarditis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Hepatitis C</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Appendiceal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Appendicitis</sub_title>
                <counts group_id="E1" events="10" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="13" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Appendicitis Perforated</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arthritis Bacterial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atypical Pneumonia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bacteraemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bacterial Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bacterial Prostatitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bacterial Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Biliary Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bone Tuberculosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Borrelia Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Cellulitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchiolitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchitis</sub_title>
                <counts group_id="E1" events="21" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="17" subjects_affected="16" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchitis Bacterial</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchitis Viral</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brucellosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bursitis Infective</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Campylobacter Gastroenteritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Candida Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cellulitis</sub_title>
                <counts group_id="E1" events="40" subjects_affected="37" subjects_at_risk="9443"/>
                <counts group_id="E2" events="35" subjects_affected="32" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cellulitis Of Male External Genital Organ</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cellulitis Staphylococcal</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholangitis Infective</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholecystitis Infective</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Sinusitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Citrobacter Sepsis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Clostridium Difficile Colitis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cutaneous Tuberculosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cystitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cytomegalovirus Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dengue Fever</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermo-Hypodermitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Device Related Infection</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Foot Infection</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Gangrene</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diverticulitis</sub_title>
                <counts group_id="E1" events="11" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diverticulitis Intestinal Haemorrhagic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Encephalitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Endocarditis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterobacter Bacteraemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterococcal Bacteraemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterococcal Sepsis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterocolitis Bacterial</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enterocolitis Infectious</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Epididymitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erysipelas</sub_title>
                <counts group_id="E1" events="9" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Escherichia Pyelonephritis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Escherichia Sepsis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Escherichia Urinary Tract Infection</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>External Ear Cellulitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Extradural Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gallbladder Empyema</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gangrene</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Ulcer Helicobacter</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastritis Viral</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastroenteritis</sub_title>
                <counts group_id="E1" events="25" subjects_affected="25" subjects_at_risk="9443"/>
                <counts group_id="E2" events="31" subjects_affected="26" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastroenteritis Bacterial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastroenteritis Salmonella</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastroenteritis Viral</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Graft Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Groin Abscess</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemophilus Sepsis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hantaviral Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Helicobacter Gastritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Amoebiasis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Infection Bacterial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatitis C</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Herpes Virus Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Herpes Zoster</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Iatrogenic Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Implant Site Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infected Bite</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infected Cyst</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infected Skin Ulcer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infectious Colitis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infectious Pleural Effusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Infective Exacerbation Of Chronic Obstructive Airways Disease</sub_title>
                <counts group_id="E1" events="9" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="12" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Influenza</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Injection Site Cellulitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Klebsiella Bacteraemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Labyrinthitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laryngitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Latent Tuberculosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Liver Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Localised Infection</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lower Respiratory Tract Infection</sub_title>
                <counts group_id="E1" events="10" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="12" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ludwig Angina</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Infection</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lyme Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mastitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mastoiditis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mediastinitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Medical Device Site Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Meningitis Aseptic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Meningoencephalitis Bacterial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Necrotising Fasciitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neutropenic Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ophthalmic Herpes Zoster</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oral Herpes</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Orchitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteomyelitis</sub_title>
                <counts group_id="E1" events="13" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteomyelitis Acute</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteomyelitis Chronic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Otitis Externa</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Otitis Media</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Otitis Media Acute</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreas Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pelvic Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pelvic Inflammatory Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Perichondritis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Perihepatic Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Perineal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Periodontitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Periorbital Cellulitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Perirectal Abscess</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peritoneal Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peritonitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peritonsillar Abscess</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pharyngitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pharyngolaryngeal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pilonidal Cyst</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pleurisy Viral</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia</sub_title>
                <counts group_id="E1" events="123" subjects_affected="108" subjects_at_risk="9443"/>
                <counts group_id="E2" events="98" subjects_affected="96" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Bacterial</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Chlamydial</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Escherichia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Haemophilus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Influenzal</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Klebsiella</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Legionella</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Mycoplasmal</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Pneumococcal</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Staphylococcal</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Streptococcal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Viral</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Cellulitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Infection</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Pneumonia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Sepsis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Viral Fatigue Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postoperative Wound Infection</sub_title>
                <counts group_id="E1" events="14" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="13" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Proctitis Bacterial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pseudomembranous Colitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pseudomonal Bacteraemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pseudomonal Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Psoas Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Sepsis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Tuberculosis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pyelonephritis</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pyelonephritis Acute</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pyelonephritis Chronic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Syncytial Virus Infection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Tract Infection</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scrotal Abscess</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scrub Typhus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sepsis</sub_title>
                <counts group_id="E1" events="38" subjects_affected="35" subjects_at_risk="9443"/>
                <counts group_id="E2" events="20" subjects_affected="20" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Septic Shock</sub_title>
                <counts group_id="E1" events="13" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinusitis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinusitis Bacterial</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Staphylococcal Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Staphylococcal Bacteraemia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Staphylococcal Osteomyelitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Staphylococcal Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Streptococcal Bacteraemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Streptococcal Endocarditis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Streptococcal Sepsis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Subcutaneous Abscess</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Systemic Infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tonsillitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tooth Abscess</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Toxic Shock Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tracheitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tracheobronchitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tuberculosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tuberculous Pleurisy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Upper Respiratory Tract Infection</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urethritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Tract Infection</sub_title>
                <counts group_id="E1" events="35" subjects_affected="33" subjects_at_risk="9443"/>
                <counts group_id="E2" events="28" subjects_affected="27" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Tract Infection Bacterial</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Tract Infection Enterococcal</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Tract Infection Staphylococcal</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urosepsis</sub_title>
                <counts group_id="E1" events="11" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="16" subjects_affected="16" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vestibular Neuronitis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Viral Cardiomyopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Viral Infection</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Viral Labyrinthitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Viral Myocarditis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Viral Pericarditis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Viral Upper Respiratory Tract Infection</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Visceral Leishmaniasis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vulval Abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vulvovaginal Candidiasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Wound Infection</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Wound Infection Staphylococcal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Injury, poisoning and procedural complications</title>
            <event_list>
              <event>
                <sub_title>Abdominal Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Abdominal Wound Dehiscence</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Accidental Overdose</sub_title>
                <counts group_id="E1" events="14" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acetabulum Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Alcohol Poisoning</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Allergic Transfusion Reaction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaemia Postoperative</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaesthetic Complication Neurological</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anastomotic Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ankle Fracture</sub_title>
                <counts group_id="E1" events="9" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arterial Bypass Thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arterial Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arthropod Bite</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arthropod Sting</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Auricular Haematoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blast Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bone Contusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brachial Plexus Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Contusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Herniation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carbon Monoxide Poisoning</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Contusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Valve Replacement Complication</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cervical Vertebral Fracture</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chemical Burn Of Gastrointestinal Tract</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chest Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Clavicle Fracture</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Concussion</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Confusion Postoperative</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Contusion</sub_title>
                <counts group_id="E1" events="6" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coronary Artery Restenosis</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Craniocerebral Injury</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Delayed Recovery From Anaesthesia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Electric Shock</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Extra-Axial Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Extradural Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Eye Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Face Injury</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Facial Bones Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fall</sub_title>
                <counts group_id="E1" events="34" subjects_affected="32" subjects_at_risk="9443"/>
                <counts group_id="E2" events="26" subjects_affected="26" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Femoral Neck Fracture</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Femur Fracture</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fibula Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Foot Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Forearm Fracture</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Foreign Body In Urogenital Tract</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fracture Displacement</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fractured Skull Depressed</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Stoma Necrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gun Shot Wound</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hand Fracture</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Head Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Heat Stroke</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hip Fracture</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Humerus Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyphaema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Incision Site Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Incisional Hernia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Injury</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intentional Overdose</sub_title>
                <counts group_id="E1" events="18" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Jaw Fracture</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Joint Dislocation</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Joint Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laceration</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ligament Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ligament Rupture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ligament Sprain</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Limb Crushing Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Limb Injury</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Limb Traumatic Amputation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lip Injury</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lower Limb Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lumbar Vertebral Fracture</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mallet Finger</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Meniscus Injury</sub_title>
                <counts group_id="E1" events="5" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Multiple Fractures</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Multiple Injuries</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscle Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscle Rupture</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscle Strain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nerve Root Injury Lumbar</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pelvic Fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Penetrating Abdominal Trauma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Periorbital Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Artery Restenosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Periprosthetic Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Perirenal Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumothorax Traumatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Concussion Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Laminectomy Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Bile Leak</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Fistula</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Haematuria</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Haemorrhage</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Inflammation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Pulmonary Embolism</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post Procedural Swelling</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post-Traumatic Pain</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postoperative Ileus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postoperative Renal Failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postoperative Respiratory Failure</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postoperative Thoracic Procedure Complication</sub_title>
                <counts group_id="E1" events="5" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postoperative Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postpericardiotomy Syndrome</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Procedural Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Procedural Hypertension</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Procedural Hypotension</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Procedural Intestinal Perforation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Procedural Pain</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Procedural Pneumothorax</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pubis Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Contusion</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Radiation Associated Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Radiation Skin Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Radius Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rib Fracture</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Road Traffic Accident</sub_title>
                <counts group_id="E1" events="19" subjects_affected="19" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="14" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scapula Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scrotal Haematoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Seroma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Silicosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Skin Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Skull Fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Soft Tissue Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Compression Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Cord Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Splenic Rupture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Stab Wound</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sternal Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Stoma Site Discharge</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Stomal Hernia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Subarachnoid Haemorrhage</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Subdural Haematoma</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tendon Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tendon Rupture</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thermal Burn</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thoracic Vertebral Fracture</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tibia Fracture</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tooth Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Toxicity To Various Agents</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tracheostomy Malfunction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Traumatic Haematoma</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Traumatic Haemothorax</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Traumatic Intracranial Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Traumatic Liver Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Traumatic Renal Injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Traumatic Ulcer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ulna Fracture</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Upper Limb Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Retention Postoperative</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Access Site Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Access Site Pseudoaneurysm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Graft Occlusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Pseudoaneurysm</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Pseudoaneurysm Ruptured</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Wound</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Wound Dehiscence</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Wrist Fracture</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Investigations</title>
            <event_list>
              <event>
                <sub_title>Alanine Aminotransferase Increased</sub_title>
                <counts group_id="E1" events="11" subjects_affected="11" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anticoagulation Drug Level Above Therapeutic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Calcium Increased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Creatine Phosphokinase Mb Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Creatine Phosphokinase Increased</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Creatinine Increased</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Potassium Increased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Pressure Increased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Natriuretic Peptide Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>C-Reactive Protein Increased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Stress Test Abnormal</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ejection Fraction Decreased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Electrocardiogram Qt Prolonged</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Exercise Electrocardiogram Abnormal</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Glomerular Filtration Rate Decreased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hiv Test Positive</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haematocrit Decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haematocrit Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemoglobin Decreased</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Enzyme Abnormal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Enzyme Increased</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatitis C Virus Test Positive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Human Papilloma Virus Test Positive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Influenza A Virus Test Positive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>International Normalised Ratio Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Liver Function Test Abnormal</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Liver Function Test Increased</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mycobacterium Tuberculosis Complex Test Positive</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scan Myocardial Perfusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Transaminases Increased</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Troponin Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tumour Marker Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Weight Decreased</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>White Blood Cell Count Increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Metabolism and nutrition disorders</title>
            <event_list>
              <event>
                <sub_title>Dehydration</sub_title>
                <counts group_id="E1" events="13" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetes Mellitus</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetes Mellitus Inadequate Control</sub_title>
                <counts group_id="E1" events="21" subjects_affected="16" subjects_at_risk="9443"/>
                <counts group_id="E2" events="20" subjects_affected="20" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Complication</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Ketoacidosis</sub_title>
                <counts group_id="E1" events="13" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Ketosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Metabolic Decompensation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Electrolyte Imbalance</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fluid Overload</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Fluid Retention</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gout</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperammonaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypercalcaemia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperglycaemia</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="12" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperglycaemic Hyperosmolar Nonketotic Syndrome</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperinsulinaemic Hypoglycaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperkalaemia</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypernatraemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypertriglyceridaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperuricaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypervolaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoalbuminaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypocalcaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoglycaemia</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypokalaemia</sub_title>
                <counts group_id="E1" events="12" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="13" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypomagnesaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyponatraemia</sub_title>
                <counts group_id="E1" events="9" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypovolaemia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lactic Acidosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metabolic Acidosis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metabolic Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metabolic Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Obesity</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Type 1 Diabetes Mellitus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Type 2 Diabetes Mellitus</sub_title>
                <counts group_id="E1" events="36" subjects_affected="36" subjects_at_risk="9443"/>
                <counts group_id="E2" events="37" subjects_affected="37" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Ankylosing Spondylitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arthralgia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arthritis</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arthrofibrosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Back Pain</sub_title>
                <counts group_id="E1" events="11" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bone Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bursitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cervical Spinal Stenosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chondropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Compartment Syndrome</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Costochondritis</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dupuytren's Contracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Enthesopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Femoroacetabular Impingement</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Foot Deformity</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gouty Arthritis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intervertebral Disc Degeneration</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intervertebral Disc Disorder</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intervertebral Disc Protrusion</sub_title>
                <counts group_id="E1" events="22" subjects_affected="21" subjects_at_risk="9443"/>
                <counts group_id="E2" events="21" subjects_affected="21" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Joint Effusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Joint Instability</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Joint Range Of Motion Decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lumbar Spinal Stenosis</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Meniscal Degeneration</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mobility Decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscle Necrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscle Spasms</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscle Tightness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Muscular Weakness</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Musculoskeletal Chest Pain</sub_title>
                <counts group_id="E1" events="44" subjects_affected="35" subjects_at_risk="9443"/>
                <counts group_id="E2" events="26" subjects_affected="24" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Musculoskeletal Pain</sub_title>
                <counts group_id="E1" events="5" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myalgia</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myopathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myositis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neck Pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuropathic Arthropathy</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteoarthritis</sub_title>
                <counts group_id="E1" events="51" subjects_affected="46" subjects_at_risk="9443"/>
                <counts group_id="E2" events="54" subjects_affected="50" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteochondrosis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteopenia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Osteoporotic Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pain In Extremity</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pathological Fracture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Periarthritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Polymyalgia Rheumatica</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pseudarthrosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Psoriatic Arthropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rhabdomyolysis</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rheumatic Fever</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rheumatoid Arthritis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rotator Cuff Syndrome</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Column Stenosis</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Ligament Ossification</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Osteoarthritis</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Pain</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spondylolisthesis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sympathetic Posterior Cervical Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Synovial Cyst</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Synovitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Systemic Lupus Erythematosus</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tendonitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertebral Foraminal Stenosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Neoplasms benign, malignant and unspecified (incl cysts and polyps)</title>
            <event_list>
              <event>
                <sub_title>Acute Lymphocytic Leukaemia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Myeloid Leukaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adenocarcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adenocarcinoma Gastric</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adenocarcinoma Of Colon</sub_title>
                <counts group_id="E1" events="14" subjects_affected="14" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adrenal Adenoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adrenal Neoplasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Cancer Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anal Squamous Cell Carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anaplastic Large Cell Lymphoma T- And Null-Cell Types</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>B-Cell Lymphoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>B-Cell Small Lymphocytic Lymphoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Basal Cell Carcinoma</sub_title>
                <counts group_id="E1" events="18" subjects_affected="14" subjects_at_risk="9443"/>
                <counts group_id="E2" events="12" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Benign Ovarian Tumour</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Benign Salivary Gland Neoplasm</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Cancer</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Cancer Stage Iv</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Neoplasm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Papilloma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Transitional Cell Carcinoma</sub_title>
                <counts group_id="E1" events="9" subjects_affected="9" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Transitional Cell Carcinoma Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Transitional Cell Carcinoma Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bowen's Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Neoplasm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Neoplasm Benign</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Cancer</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Cancer Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Cancer Stage I</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Cancer Stage Ii</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Cancer Stage Iii</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchial Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cancer Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carcinoid Tumour Of The Appendix</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carcinoid Tumour Pulmonary</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Myxoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cardiac Valve Fibroelastoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebellar Tumour</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cervix Carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cervix Carcinoma Stage Ii</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cholesteatoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Lymphocytic Leukaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Myeloid Leukaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Myelomonocytic Leukaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Clear Cell Renal Cell Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colon Adenoma</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colon Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colon Cancer Metastatic</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colon Cancer Stage Iii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colon Cancer Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colorectal Adenocarcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colorectal Cancer Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Colorectal Cancer Stage Iii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Craniopharyngioma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diffuse Large B-Cell Lymphoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ductal Adenocarcinoma Of Pancreas</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Endometrial Adenocarcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastric Cancer Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Stromal Tumour</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrointestinal Tract Adenoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Gastrooesophageal Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Glioblastoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Glioblastoma Multiforme</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemangioma Of Bone</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hair Follicle Tumour Benign</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Cancer</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatic Neoplasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hepatocellular Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hodgkin's Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hodgkin's Disease Stage Iv</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypopharyngeal Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Inflammatory Pseudotumour</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intraductal Proliferative Breast Lesion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Invasive Ductal Breast Carcinoma</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Invasive Lobular Breast Carcinoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Large Cell Lung Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Large Cell Lung Cancer Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laryngeal Cancer Stage I</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laryngeal Squamous Cell Carcinoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lentigo Maligna</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lip Squamous Cell Carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lipoma</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Adenocarcinoma</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Adenocarcinoma Stage I</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Adenocarcinoma Stage Ii</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Adenocarcinoma Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Adenocarcinoma Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Cancer Metastatic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Carcinoma Cell Type Unspecified Stage I</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Carcinoma Cell Type Unspecified Stage Iii</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Carcinoma Cell Type Unspecified Stage Iv</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Neoplasm</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Neoplasm Malignant</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Squamous Cell Carcinoma Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Squamous Cell Carcinoma Stage I</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Squamous Cell Carcinoma Stage Ii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Squamous Cell Carcinoma Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Squamous Cell Carcinoma Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lymphoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Anorectal Neoplasm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Ascites</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Glioma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Melanoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Melanoma In Situ</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Melanoma Stage I</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Melanoma Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Melanoma Stage Iv</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Palate Neoplasm</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Pleural Effusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Sweat Gland Neoplasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Meningioma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Bone</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Central Nervous System</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Liver</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Lung</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Lymph Nodes</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Peritoneum</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastases To Spine</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Bronchial Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Carcinoma Of The Bladder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Gastric Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Malignant Melanoma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Neoplasm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Renal Cell Carcinoma</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metastatic Squamous Cell Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Monoclonal Gammopathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mucinous Cystadenocarcinoma Ovary</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myelodysplastic Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myeloproliferative Neoplasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nasal Cavity Cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuroendocrine Carcinoma Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuroendocrine Tumour</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuroendocrine Tumour Of The Lung</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuroendocrine Tumour Of The Lung Metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Hodgkin's Lymphoma</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Hodgkin's Lymphoma Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Hodgkin's Lymphoma Recurrent</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Small Cell Lung Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Small Cell Lung Cancer Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Small Cell Lung Cancer Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Non-Small Cell Lung Cancer Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Adenocarcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Adenocarcinoma Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oesophageal Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oropharyngeal Cancer Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Oropharyngeal Squamous Cell Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ovarian Adenoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Carcinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Carcinoma Metastatic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Carcinoma Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Carcinoma Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pancreatic Neuroendocrine Tumour</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Papillary Thyroid Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Parathyroid Tumour Benign</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Penile Cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peritoneal Mesothelioma Malignant</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Phaeochromocytoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pituitary Tumour Benign</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Plasma Cell Leukaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Plasma Cell Myeloma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Plasmacytoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pleural Mesothelioma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Polycythaemia Vera</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostate Cancer</sub_title>
                <counts group_id="E1" events="17" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="18" subjects_affected="18" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostate Cancer Metastatic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostate Cancer Stage I</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostate Cancer Stage Ii</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostate Cancer Stage Iii</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostate Cancer Stage Iv</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostatic Adenoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Adenocarcinoma</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Adenoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Cancer Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectal Neoplasm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectosigmoid Cancer Stage Ii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cancer</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cancer Metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cancer Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cell Carcinoma Stage I</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cell Carcinoma Stage Ii</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cell Carcinoma Stage Iii</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Oncocytoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Salivary Gland Cancer Stage Iv</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Schwannoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Seborrhoeic Keratosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinonasal Papilloma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sinus Cancer Metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Skin Cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Skin Papilloma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Small Cell Lung Cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Small Cell Lung Cancer Limited Stage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Small Cell Lung Cancer Metastatic</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Squamous Cell Carcinoma Of Lung</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Squamous Cell Carcinoma Of Skin</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Squamous Cell Carcinoma Of The Cervix</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Squamous Cell Carcinoma Of The Hypopharynx</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Squamous Cell Carcinoma Of The Tongue</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Squamous Cell Carcinoma Of The Vulva</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Synovial Sarcoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tongue Carcinoma Stage Iv</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tonsil Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Transitional Cell Cancer Of Renal Pelvis And Ureter Metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Transitional Cell Carcinoma</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tumour Haemorrhage</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Bladder Sarcoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Uterine Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Uterine Leiomyoma</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vocal Cord Neoplasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vulval Cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vulval Cancer Metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Nervous system disorders</title>
            <event_list>
              <event>
                <sub_title>Alcoholic Seizure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Amnesia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Amyotrophic Lateral Sclerosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aphasia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ataxia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Autonomic Nervous System Imbalance</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Axonal Neuropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Balance Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Brain Oedema</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carotid Arteriosclerosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carotid Artery Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carotid Artery Occlusion</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carotid Artery Stenosis</sub_title>
                <counts group_id="E1" events="19" subjects_affected="19" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="14" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carotid Artery Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carotid Sinus Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Carpal Tunnel Syndrome</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cauda Equina Syndrome</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebral Atrophy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebral Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebral Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebral Ischaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebrospinal Fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cerebrovascular Accident</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cervical Radiculopathy</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Inflammatory Demyelinating Polyradiculoneuropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cognitive Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coma</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Coordination Abnormal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cubital Tunnel Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dementia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dementia Alzheimer's Type</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Demyelinating Polyneuropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Depressed Level Of Consciousness</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Encephalopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Neuropathy</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dizziness</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dizziness Exertional</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dysarthria</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Encephalopathy</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Epilepsy</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Epileptic Encephalopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Essential Tremor</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Extrapyramidal Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Facial Paralysis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Focal Dyscognitive Seizures</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Generalised Tonic-Clonic Seizure</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhage Intracranial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemorrhagic Stroke</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Headache</sub_title>
                <counts group_id="E1" events="8" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hemianopia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hemiparesis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hemiplegia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperaesthesia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperglycaemic Seizure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoaesthesia</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoglycaemic Seizure</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyponatraemic Seizure</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoxic-Ischaemic Encephalopathy</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intercostal Neuralgia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intracranial Aneurysm</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intracranial Mass</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intracranial Venous Sinus Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intraventricular Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ischaemic Stroke</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Limbic Encephalitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Loss Of Consciousness</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lumbar Radiculopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lumbosacral Radiculopathy</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Memory Impairment</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metabolic Encephalopathy</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Migraine</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Migraine With Aura</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mixed Dementia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Monoparesis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Multiple Sclerosis Relapse</sub_title>
                <counts group_id="E1" events="3" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myelopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Myoclonus</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nerve Compression</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuralgia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuromuscular Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Neuropathy Peripheral</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Occipital Neuralgia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Paraesthesia</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Paralysis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Parkinson's Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Parkinsonism</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Partial Seizures With Secondary Generalisation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Nerve Lesion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Sensory Neuropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Petit Mal Epilepsy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Polyneuropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Posterior Reversible Encephalopathy Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postictal Paralysis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Presyncope</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pyramidal Tract Syndrome</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Radial Nerve Palsy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Radicular Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Radiculopathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ruptured Cerebral Aneurysm</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sciatica</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Seizure</sub_title>
                <counts group_id="E1" events="7" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sensory Loss</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spinal Cord Compression</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spondylitic Myelopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Status Epilepticus</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Syncope</sub_title>
                <counts group_id="E1" events="82" subjects_affected="73" subjects_at_risk="9443"/>
                <counts group_id="E2" events="73" subjects_affected="67" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Toxic Encephalopathy</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Transient Global Amnesia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Transient Ischaemic Attack</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tremor</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Trigeminal Neuralgia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ulnar Neuritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ulnar Tunnel Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vith Nerve Paralysis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vith Nerve Paresis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Encephalopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertebral Artery Occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertebrobasilar Insufficiency</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vertigo Cns Origin</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Product Issues</title>
            <event_list>
              <event>
                <sub_title>Device Dislocation</sub_title>
                <counts group_id="E1" events="3" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Device Lead Damage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Device Malfunction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Device Occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lead Dislodgement</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thrombosis In Device</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Psychiatric disorders</title>
            <event_list>
              <event>
                <sub_title>Acute Psychosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adjustment Disorder With Mixed Disturbance Of Emotion And Conduct</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Affective Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Agoraphobia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Alcohol Abuse</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Alcoholic Psychosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Alcoholism</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anger</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anxiety</sub_title>
                <counts group_id="E1" events="9" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Anxiety Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bipolar I Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bipolar Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Borderline Personality Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bradyphrenia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Catatonia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Completed Suicide</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Confusional State</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Conversion Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Delirium</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Delirium Tremens</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Delusional Disorder, Unspecified Type</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Depression</sub_title>
                <counts group_id="E1" events="26" subjects_affected="25" subjects_at_risk="9443"/>
                <counts group_id="E2" events="18" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Depression Suicidal</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Drug Abuse</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Factitious Disorder</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hallucination</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Homicidal Ideation</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Insomnia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Major Depression</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mental Status Changes</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Mood Disorder Due To A General Medical Condition</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Panic Attack</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Post-Traumatic Stress Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sleep Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Suicidal Behaviour</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Suicidal Ideation</sub_title>
                <counts group_id="E1" events="10" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Suicide Attempt</sub_title>
                <counts group_id="E1" events="15" subjects_affected="14" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Transient Psychosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Renal and urinary disorders</title>
            <event_list>
              <event>
                <sub_title>Acute Kidney Injury</sub_title>
                <counts group_id="E1" events="74" subjects_affected="62" subjects_at_risk="9443"/>
                <counts group_id="E2" events="59" subjects_affected="57" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Prerenal Failure</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Dilatation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Outlet Obstruction</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Perforation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bladder Tamponade</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Calculus Bladder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Calculus Urinary</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Kidney Disease</sub_title>
                <counts group_id="E1" events="16" subjects_affected="15" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="13" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cystitis Glandularis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cystitis Interstitial</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cystitis Noninfective</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Cystopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Nephropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>End Stage Renal Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Glomerulonephritis Proliferative</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Glomerulonephropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haematuria</sub_title>
                <counts group_id="E1" events="15" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="9" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hydronephrosis</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypertensive Nephropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Iga Nephropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lower Urinary Tract Symptoms</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nephrolithiasis</sub_title>
                <counts group_id="E1" events="21" subjects_affected="21" subjects_at_risk="9443"/>
                <counts group_id="E2" events="15" subjects_affected="15" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nephropathy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nephropathy Toxic</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nephrosclerosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nephrotic Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pelvi-Ureteric Obstruction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Postrenal Failure</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Artery Occlusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Artery Stenosis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Colic</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cyst</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Cyst Haemorrhage</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Failure</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="8" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Impairment</sub_title>
                <counts group_id="E1" events="4" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Infarct</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Mass</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Tubular Disorder</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Tubular Necrosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renal Vein Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Stress Urinary Incontinence</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tubulointerstitial Nephritis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ureteral Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ureteric Stenosis</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ureterolithiasis</sub_title>
                <counts group_id="E1" events="15" subjects_affected="15" subjects_at_risk="9443"/>
                <counts group_id="E2" events="14" subjects_affected="12" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urethral Stenosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="5" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Bladder Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Bladder Rupture</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Incontinence</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Retention</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinary Tract Obstruction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urinoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urogenital Fistula</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Reproductive system and breast disorders</title>
            <event_list>
              <event>
                <sub_title>Acquired Hydrocele</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acquired Phimosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Benign Prostatic Hyperplasia</sub_title>
                <counts group_id="E1" events="13" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="16" subjects_affected="16" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Mass</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Breast Pain</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dysfunctional Uterine Bleeding</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Endometrial Hyperplasia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erectile Dysfunction</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Menorrhagia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Metrorrhagia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ovarian Cyst</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peyronie's Disease</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Prostatitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rectocele</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scrotal Ulcer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Spermatocele</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Testicular Cyst</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Uterine Haemorrhage</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Uterine Polyp</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Uterine Prolapse</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Uterovaginal Prolapse</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vaginal Dysplasia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vaginal Haemorrhage</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vaginal Prolapse</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Varicocele</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vulva Cyst</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Respiratory, thoracic and mediastinal disorders</title>
            <event_list>
              <event>
                <sub_title>Acquired Diaphragmatic Eventration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Pulmonary Oedema</sub_title>
                <counts group_id="E1" events="10" subjects_affected="10" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Respiratory Distress Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Acute Respiratory Failure</sub_title>
                <counts group_id="E1" events="35" subjects_affected="24" subjects_at_risk="9443"/>
                <counts group_id="E2" events="21" subjects_affected="19" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Adenoidal Hypertrophy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aspiration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Asthma</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Atelectasis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchial Hyperreactivity</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchiectasis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchitis Chronic</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Bronchospasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Choking</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Obstructive Pulmonary Disease</sub_title>
                <counts group_id="E1" events="76" subjects_affected="51" subjects_at_risk="9443"/>
                <counts group_id="E2" events="47" subjects_affected="38" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Chronic Respiratory Failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Cough</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dyspnoea</sub_title>
                <counts group_id="E1" events="12" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="21" subjects_affected="20" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dyspnoea Exertional</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Emphysema</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Epistaxis</sub_title>
                <counts group_id="E1" events="12" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemoptysis</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haemothorax</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperventilation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoventilation</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypoxia</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Idiopathic Pulmonary Fibrosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Interstitial Lung Disease</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laryngeal Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laryngeal Oedema</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Laryngospasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Disorder</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lung Infiltration</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nasal Mucosal Ulcer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nasal Obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nasal Polyps</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nasal Septum Deviation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Nasal Turbinate Hypertrophy</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pleural Effusion</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pleurisy</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pleuritic Pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumonia Aspiration</sub_title>
                <counts group_id="E1" events="8" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pneumothorax</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Alveolar Haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Calcification</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Congestion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Embolism</sub_title>
                <counts group_id="E1" events="19" subjects_affected="19" subjects_at_risk="9443"/>
                <counts group_id="E2" events="16" subjects_affected="16" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Fibrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Hypertension</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Infarction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Mass</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pulmonary Oedema</sub_title>
                <counts group_id="E1" events="5" subjects_affected="5" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Acidosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Arrest</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Distress</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Failure</sub_title>
                <counts group_id="E1" events="16" subjects_affected="15" subjects_at_risk="9443"/>
                <counts group_id="E2" events="11" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Respiratory Tract Oedema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rhinitis Allergic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Sleep Apnoea Syndrome</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Tonsillolith</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vocal Cord Disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vocal Cord Polyp</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Wheezing</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Skin and subcutaneous tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Angioedema</sub_title>
                <counts group_id="E1" events="8" subjects_affected="7" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Decubitus Ulcer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermal Cyst</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatitis Allergic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatitis Atopic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatitis Bullous</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatitis Contact</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatitis Exfoliative Generalised</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dermatomyositis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Foot</sub_title>
                <counts group_id="E1" events="11" subjects_affected="11" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="6" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Neuropathic Ulcer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Diabetic Ulcer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Drug Eruption</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Drug Reaction With Eosinophilia And Systemic Symptoms</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Eczema Nummular</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erythema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erythema Multiforme</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Erythrodermic Psoriasis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hyperhidrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intertrigo</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Photosensitivity Reaction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Pruritus Allergic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Psoriasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rash</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rash Erythematous</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Rash Pruritic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Scar Pain</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Skin Lesion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Skin Ulcer</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Swelling Face</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urticaria</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Urticaria Chronic</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Vascular Purpura</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Social circumstances</title>
            <event_list>
              <event>
                <sub_title>Physical Assault</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Vascular disorders</title>
            <event_list>
              <event>
                <sub_title>Accelerated Hypertension</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Aneurysm</sub_title>
                <counts group_id="E1" events="12" subjects_affected="12" subjects_at_risk="9443"/>
                <counts group_id="E2" events="10" subjects_affected="10" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Aneurysm Rupture</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Dissection</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Intramural Haematoma</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Stenosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aortic Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Aorto-Duodenal Fistula</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arterial Insufficiency</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arteriosclerosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Arteriovenous Fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Blood Pressure Inadequately Controlled</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Circulatory Collapse</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Deep Vein Thrombosis</sub_title>
                <counts group_id="E1" events="9" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="13" subjects_affected="11" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Dry Gangrene</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Embolism</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Embolism Venous</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Essential Hypertension</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Extremity Necrosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hot Flush</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypertension</sub_title>
                <counts group_id="E1" events="41" subjects_affected="36" subjects_at_risk="9443"/>
                <counts group_id="E2" events="35" subjects_affected="34" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypertensive Crisis</sub_title>
                <counts group_id="E1" events="19" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="22" subjects_affected="21" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypertensive Emergency</sub_title>
                <counts group_id="E1" events="7" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypotension</sub_title>
                <counts group_id="E1" events="17" subjects_affected="17" subjects_at_risk="9443"/>
                <counts group_id="E2" events="16" subjects_affected="16" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Hypovolaemic Shock</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Iliac Artery Embolism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Iliac Artery Occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Intermittent Claudication</sub_title>
                <counts group_id="E1" events="7" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="4" subjects_affected="4" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Ischaemic Limb Pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Leriche Syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lymphatic Fistula</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lymphoedema</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Lymphorrhoea</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Malignant Hypertension</sub_title>
                <counts group_id="E1" events="4" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Orthostatic Hypotension</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Penetrating Aortic Ulcer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Arterial Occlusive Disease</sub_title>
                <counts group_id="E1" events="49" subjects_affected="47" subjects_at_risk="9443"/>
                <counts group_id="E2" events="29" subjects_affected="27" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Artery Aneurysm</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="6" subjects_affected="5" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Artery Dissection</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Artery Occlusion</sub_title>
                <counts group_id="E1" events="15" subjects_affected="13" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Artery Stenosis</sub_title>
                <counts group_id="E1" events="11" subjects_affected="8" subjects_at_risk="9443"/>
                <counts group_id="E2" events="9" subjects_affected="8" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Artery Thrombosis</sub_title>
                <counts group_id="E1" events="5" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Embolism</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Ischaemia</sub_title>
                <counts group_id="E1" events="23" subjects_affected="20" subjects_at_risk="9443"/>
                <counts group_id="E2" events="7" subjects_affected="7" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Vascular Disorder</sub_title>
                <counts group_id="E1" events="6" subjects_affected="6" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Peripheral Venous Disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="2" subjects_affected="2" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Phlebitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Phlebitis Superficial</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Raynaud's Phenomenon</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Renovascular Hypertension</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Shock</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Shock Haemorrhagic</sub_title>
                <counts group_id="E1" events="4" subjects_affected="4" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Subclavian Artery Occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Subclavian Artery Stenosis</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Superior Vena Cava Occlusion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Temporal Arteritis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thrombophlebitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thrombophlebitis Superficial</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Thrombosis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Varicose Vein</sub_title>
                <counts group_id="E1" events="3" subjects_affected="3" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Venous Thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="9443"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="9451"/>
              </event>
              <event>
                <sub_title>Venous Thrombosis Limb</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="9443"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </serious_events>
      <other_events>
        <frequency_threshold>5</frequency_threshold>
        <default_vocab>MedDra 20.1</default_vocab>
        <default_assessment>Systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, other adverse events</sub_title>
                <counts group_id="E1" subjects_affected="2181" subjects_at_risk="9443"/>
                <counts group_id="E2" subjects_affected="2203" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>General disorders</title>
            <event_list>
              <event>
                <sub_title>Non-Cardiac Chest Pain</sub_title>
                <counts group_id="E1" events="556" subjects_affected="462" subjects_at_risk="9443"/>
                <counts group_id="E2" events="591" subjects_affected="481" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Nasopharyngitis</sub_title>
                <counts group_id="E1" events="697" subjects_affected="532" subjects_at_risk="9443"/>
                <counts group_id="E2" events="713" subjects_affected="567" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Investigations</title>
            <event_list>
              <event>
                <sub_title>Blood Creatine Phosphokinase Increased</sub_title>
                <counts group_id="E1" events="560" subjects_affected="488" subjects_at_risk="9443"/>
                <counts group_id="E2" events="521" subjects_affected="457" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Myalgia</sub_title>
                <counts group_id="E1" events="563" subjects_affected="496" subjects_at_risk="9443"/>
                <counts group_id="E2" events="591" subjects_affected="522" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Vascular disorders</title>
            <event_list>
              <event>
                <sub_title>Hypertension</sub_title>
                <counts group_id="E1" events="678" subjects_affected="574" subjects_at_risk="9443"/>
                <counts group_id="E2" events="600" subjects_affected="542" subjects_at_risk="9451"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </other_events>
    </reported_events>

    <certain_agreements>
      <pi_employee>Principal Investigators are NOT employed by the organization sponsoring the study.</pi_employee>
      <restrictive_agreement>If no publication has occurred within 12 months of the completion of the study, the Investigator shall have the right to publish/present independently the results of the study. The Investigator shall provide the Sponsor with a copy of any such presentation/publication for comment at least 30 days before any presentation/submission for publication. If requested by the Sponsor, any presentation/submission shall be delayed up to 90 days, to allow the Sponsor to preserve its proprietary rights.</restrictive_agreement>
    </certain_agreements>
    <point_of_contact>
      <name_or_title>Trial Transparency Team</name_or_title>
      <organization>Sanofi</organization>
      <phone>800-633-1610 ext 1</phone>
      <email>Contact-US@sanofi.com</email>
    </point_of_contact>
  </clinical_results>
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT01663402
org study id: EFC11570
secondary id: 2011-005698-21
secondary id: U1111-1127-4323
nct id: NCT01663402
lead sponsor: 
collaborator: 
has dmc: Yes
Primary Objective:

      To compare the effect of alirocumab with placebo on the occurrence of cardiovascular (CV)
      events (composite endpoint of coronary heart disease (CHD) death, non-fatal myocardial
      infarction (MI), fatal and non-fatal ischemic stroke, unstable angina (UA) requiring
      hospitalization) in participants who experienced an acute coronary syndrome (ACS) event 4 to
      52 weeks prior to randomization and were treated with evidence-based medical and dietary
      management of dyslipidemia.

      Secondary Objectives:

        -  To evaluate the effect of alirocumab on secondary endpoints (any CHD event , major CHD
           event, any CV event, composite of all cause mortality/non-fatal MI/non-fatal ischemic
           stroke, CHD deaths, CV deaths, all cause mortality).

        -  To evaluate the safety and tolerability of alirocumab.

        -  To evaluate the effect of alirocumab on lipid parameters.
18924 number of participants aged >= 40 years old were randomized in the study.
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Prevention
masking: Double (Participant, Investigator)
measure: Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: All MACE positively adjudicated by Clinical Events Committee (CEC) in a blinded fashion, were used in the analysis of the composite cardiovascular (CV) outcome measure comprised of Coronary Heart Disease (CHD) death, non-fatal Myocardial Infarction (MI), fatal and non-fatal ischemic stroke (IS), or unstable angina (UA) requiring hospitalization. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of MACE over time. Percentage of observed participants with outcome measure events during the study were reported.
measure: Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: All CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death, non-fatal non-fatal MI, UA requiring hospitalization, or ischemia-driven coronary revascularization procedure. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.
measure: Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: All Major CHD events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CHD endpoint comprised of any CHD death and non-fatal MI. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any major CHD event over time. Percentage of observed participants with outcome measure events during the study were reported.
measure: Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: All CV events positively adjudicated by CEC in a blinded fashion, were used in the analysis of the composite CV endpoint comprised of any non-fatal CHD event, any CV death and non-fatal IS. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CV event over time. Percentage of observed participants with outcome measure events during the study were reported.
measure: Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: All-cause mortality, non-fatal MI and non-fatal IS positively adjudicated by CEC in a blinded fashion, were used in the analysis of this endpoint. Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of all-cause mortality, non-fatal MI and non-fatal IS over time. Percentage of observed participants with outcome measure events during the study were reported.
measure: Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CHD death over time. Percentage of observed participants with CHD death (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the CV death over time. Percentage of observed participants with CV death (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the all-cause death over time. Percentage of observed participants with all-cause death (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any non-fatal MI over time. Percentage of observed participants with any non-fatal MI (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of fatal or any non-fatal IS over time. Percentage of observed participants with fatal or any non-fatal IS (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any UA requiring hospitalization over time. Percentage of observed participants with any UA requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any ischemia-driven coronary revascularization procedure over time. Percentage of observed participants with any ischemia-driven coronary revascularization procedure (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study
time frame: From randomization up to 64 months
description: Kaplan Meier plots of the cumulative incidence rate by treatment groups were used to depict the first occurrence of any CHF requiring hospitalization over time. Percentage of observed participants with any CHF requiring hospitalization (positively adjudicated by CEC in a blinded fashion) were reported.
measure: Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis
time frame: Baseline, Months 4, 12 and 48
description: Adjusted means and standard errors at Month 4, 12 and 48 from multiple imputation approach (to account for missing data) followed by analyses of covariance (ANCOVA) model with the fixed categorical effect of treatment group and the continuous fixed covariate of baseline LDL-C value, including all available post-baseline data from Month 1 up to Month 48 regardless of status on- or off-treatment.
measure: Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: On-Treatment Analysis
time frame: Baseline, Months 4, 12 and 48
description: Adjusted Least-squares (LS) means and standard errors at Month 4, 12 and 48 were obtained from a mixed-effect model with repeated measures (MMRM) including available post-baseline on-treatment data from Month 1 up to Month 48 (i.e. up to 21 days after last injection).
arm group label: Placebo
arm group type: Placebo Comparator
description: Placebo (for alirocumab) subcutaneous (SC) injection every 2 weeks (Q2W) added to stable Lipid-Modifying Therapy (LMT) for up to 64 months.
arm group label: Alirocumab 75 mg Q2W/Up to 150 mg Q2W
arm group type: Experimental
description: Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when Low-Density Lipoprotein Cholesterol (LDL-C) levels >=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were <25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were <15 mg/dL (0.39 mmol/L).
intervention type: Drug
intervention name: Alirocumab
description: Alirocumab administered as SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.
arm group label: Alirocumab 75 mg Q2W/Up to 150 mg Q2W
other name: SAR236553
other name: REGN727
other name: Praluent®
intervention type: Drug
intervention name: Placebo
description: Placebo matched to alirocumab administered as a SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.
arm group label: Placebo
intervention type: Drug
intervention name: LMT
description: Statins (atorvastatin or rosuvastatin) at stable maximal tolerated dose of statin with or without other LMT as clinically indicated.
arm group label: Alirocumab 75 mg Q2W/Up to 150 mg Q2W
arm group label: Placebo
criteria: 
gender: All
minimum age: 40 Years
maximum age: N/A
healthy volunteers: No
last name: Clinical Sciences & Operations
role: Study Director
affiliation: Sanofi
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country: Argentina
country: Australia
country: Austria
country: Belgium
country: Bosnia and Herzegovina
country: Brazil
country: Bulgaria
country: Canada
country: Chile
country: China
country: Colombia
country: Croatia
country: Czechia
country: Denmark
country: Estonia
country: Finland
country: France
country: Georgia
country: Germany
country: Greece
country: Guatemala
country: Hong Kong
country: Hungary
country: India
country: Israel
country: Italy
country: Japan
country: Korea, Republic of
country: Latvia
country: Lithuania
country: Macedonia, The Former Yugoslav Republic of
country: Malaysia
country: Mexico
country: Netherlands
country: New Zealand
country: Norway
country: Peru
country: Philippines
country: Poland
country: Portugal
country: Romania
country: Russian Federation
country: Serbia
country: Singapore
country: Slovakia
country: Slovenia
country: South Africa
country: Spain
country: Sri Lanka
country: Sweden
country: Switzerland
country: Taiwan
country: Thailand
country: Turkey
country: Ukraine
country: United Kingdom
country: United States
country: Czech Republic
responsible party type: Sponsor
mesh term: Cardiovascular Diseases
mesh term: Acute Coronary Syndrome
mesh term: Atherosclerosis
mesh term: Alirocumab
provided document: 
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