<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT01693562</url>
  </required_header>
  <id_info>
    <org_study_id>CD-ON-MEDI4736-1108</org_study_id>
    <nct_id>NCT01693562</nct_id>
  </id_info>
  <brief_title>A Phase 1/2 Study to Evaluate MEDI4736</brief_title>
  <official_title>A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4736 in Subjects With Advanced Solid Tumors</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>MedImmune LLC</agency>
      <agency_class>Industry</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>MedImmune LLC</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>Yes</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      This is a multicenter, open-label, first-time-in-human study with a standard 3+3&#xD;
      dose-escalation phase in participants with advanced solid tumors followed by an expansion&#xD;
      phase in participants with advanced solid tumors. An exploration cohort has been added to&#xD;
      determine the safety using every 4 weeks (Q4W) dosing.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      A dose-escalation and dose-expansion study of MEDI4736 (a monoclonal antibody that targets&#xD;
      programmed cell death ligand-1 (PD-L1)) will evaluate the safety, tolerability,&#xD;
      pharmacokinetics (PK), immunogenicity (IM), and antitumor activity of MEDI4736 in adult&#xD;
      participants with solid tumors. A dose exploration cohort will look at the safety profile of&#xD;
      Q4W dosing of MEDI4736.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Completed</overall_status>
  <start_date type="Actual">September 5, 2012</start_date>
  <completion_date type="Actual">February 28, 2020</completion_date>
  <primary_completion_date type="Actual">February 28, 2020</primary_completion_date>
  <phase>Phase 1/Phase 2</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>N/A</allocation>
    <intervention_model>Single Group Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Number of Participants With Dose-limiting Toxicities in the Dose-escalation Phase</measure>
    <time_frame>For MEDI4736 0.1 to MEDI4736 10 mg/kg arms: from Day 1 to Day 28 of first dose; for MEDI4736 15 mg/kg arm: from Day 1 to Day 42 of first dose</time_frame>
    <description>A DLT was defined as any Grade 3 or higher treatment-related toxicity that occurred during the DLT-evaluation period including any &gt;= Grade 3 colitis or &gt;= Grade 3 immune-related adverse event (irAE; AEs of immune nature in the absence of a clear alternative etiology) including rash, pruritus, or diarrhea that did not downgrade to =&lt; Grade 2 within 3 days after onset of the event despite maximal supportive care including systemic corticosteroids. The DLT-evaluation period for 0.1 to 10 mg/kg arms was from Day 1 to Day 28 of first dose and for 15 mg/kg arm was from Day 1 to Day 42 of first dose.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs) in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</measure>
    <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
    <description>An adverse event (AE) is any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship. A serious adverse event (SAE) is an AE resulting in any of the following outcomes or deemed significant for any other reason: death; initial or prolonged inpatient hospitalization; life threatening experience (immediate risk of dying); persistent or significant disability/incapacity; congenital anomaly. The TEAEs are defined as events present at baseline that worsened in intensity after administration of study drug or events absent at baseline that emerged after administration of study drug.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Number of Participants With Abnormal Clinical Laboratory Parameters Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</measure>
    <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
    <description>Number of participants with abnormal clinical laboratory parameters reported as TEAEs are reported. Abnormal clinical laboratory parameters defined as any abnormal finding during analysis of coagulation, urine, hematology, and serum chemistry.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Number of Participants With Abnormal Vital Signs Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</measure>
    <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
    <description>Number of participants with abnormal vital signs reported as TEAEs are reported. Abnormal vital signs are defined as any abnormal finding in the vital sign parameters (body weight, body temperature, blood pressure, pulse rate, and respiratory rate).</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Number of Participants With Change From Baseline in QT/QTc Interval in Local Electrocardiogram in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</measure>
    <time_frame>From Baseline (Day 1) through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
    <description>Number of participants with change from baseline in notable QT/QTc interval in local electrocardiogram (ECG) are reported. The data for &gt;0 participants with notable QT/QTc interval in local ECG from baseline are reported.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Objective Response Rate (ORR) Assessed by Blinded Independent Central Review (BICR) in Participants With Non-squamous NSCLC Who Had Received 2 or More Prior Lines of Therapy in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The ORR assessed by BICR in participants with non-squamous NSCLC who had received 2 or more prior lines of therapy is reported. The ORR is defined as best overall response (BOR) of confirmed complete response (CR) or confirmed partial response (PR) based on Response Evaluation Criteria in Solid Tumours Version 1.1 (RECIST v1.1). The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>ORR Assessed by BICR in Participants With Squamous NSCLC Who Had Received 1 and 2 or More Prior Lines of Therapy in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The ORR assessed by BICR in participants with squamous NSCLC who had received 1 and 2 or more prior lines of therapy is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>ORR Assessed by BICR in Participants With UC Post-platinum (Programmed Cell Death Ligand [PD-L1] Status High) Who Had Received at Least 1 Line of Prior Therapy (2L+) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The ORR assessed by BICR in participants with UC post-platinum PD-L1 status high 2L+ is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Area Under the Serum Concentration-time Curve up to the Last Measurable Concentration (AUClast) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase</measure>
    <time_frame>After the first dose between Day 0 and Day 15 (Day 1 [pre and post dose] and predose of Dose 2 for all cohorts; Days 3, 5, 10 for Cohorts 0.1mg/kg to 10 mg/kg; Days 3, 5, 10, 15 for Cohort 15 mg/kg; Day 15 for Cohort 20 mg/kg)</time_frame>
    <description>Area under the concentration-time curve from time zero to the last measurable concentration (AUClast) of MEDI4736 is reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Maximum Serum Concentration (Cmax) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase</measure>
    <time_frame>After the first dose between Day 0 and Day 15 (Day 1 [pre and post dose] and predose of Dose 2 for all cohorts; Days 3, 5, 10 for Cohorts 0.1mg/kg to 10 mg/kg; Days 3, 5, 10, 15 for Cohort 15 mg/kg; Day 15 for Cohort 20 mg/kg)</time_frame>
    <description>The Cmax of MEDI4736 is reported.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Number of Participants With Positive Anti-drug Antibodies (ADA) to MEDI4736 in the Dose-escalation, Dose-exploration Phase, and Dose-expansion Phase.</measure>
    <time_frame>Escalation: Day1 of Dose(D)1 &amp; D3, even numbered doses after D4; Exploration: Day1 of D1 &amp; D2, even numbered doses after D2; Expansion: Day1 of D1, every 12 weeks since D3; all phases: till EOT, 30 days and 3 and 6 months post last dose (~5.25 years)</time_frame>
    <description>Number of participants with positive ADA titer to MEDI4736 are reported. Treatment-boosted ADA is defined as baseline positive ADA titer that was boosted to a 4-fold or higher level following drug administration; persistent positive is defined as positive at &gt;= 2 post-baseline assessments (with &gt;= 16 weeks between first and last positive) or positive at last post-baseline assessment; and transient positive is defined as having at least one post-baseline ADA-positive assessment and not fulfilling the condition of persistent positive.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Number of Participants With Best Overall Response (BOR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The BOR assessed by BICR based on RECIST v1.1 in NSCLC and SCCHN cohorts is reported. The BOR includes CR, PR, stable disease (SD), progressive disease (PD), and non-evaluable (NE). The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Number of Participants With BOR Assessed by Investigator in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The BOR assessed by investigator based on RECIST v1.1 is reported. The BOR includes CR, PR, SD, PD, and NE. The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Duration of Response (DoR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The DoR assessed by BICR in NSCLC and SCCHN cohorts is reported. The DoR is defined as the duration from the first documentation of objective response (OR) (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>DoR Assessed by Investigator in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The DoR in participants assessed by the investigator is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Disease Control Rate (DCR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>Percentage of participants with disease control assessed by BICR in NSCLC and SCCHN cohorts is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>DCR Assessed by Investigator in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>Percentage of participants with disease control assessed by the investigator is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Progression-free Survival (PFS) Assessed by BICR in NSCLC Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The PFS assessed by BICR in NSCLC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>PFS Assessed by BICR in SCCHN Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The PFS assessed by BICR in SCCHN cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>PFS Assessed by Investigator in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The PFS assessed by the investigator is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>OS in the Dose-Expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>ORR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The ORR assessed by BICR in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>ORR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The ORR assessed by the investigator in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>DoR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The DoR assessed by BICR in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>DoR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The DoR assessed by investigator in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>DCR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>Percentage of participants with disease control assessed by BICR in UC cohort is reported. The DCR is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>DCR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>Percentage of participants with disease control assessed by investigator in UC cohort is reported. Disease control is defined as a best overall response of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR not sufficient increase to qualify for disease progression.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>PFS Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The PFS assessed by BICR in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>PFS Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The PFS assessed by the investigator in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>OS in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The OS in UC cohort is reported. The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Adjusted Comparison of PFS by PD-L1 Status in UC Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The PFS by PD-L1 status in UC cohort is reported. The PFS estimates are adjusted for baseline eastern cooperative oncology (ECOG), smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Adjusted Comparison of OS by PD-L1 Status in UC Cohort in the Dose-expansion Phase</measure>
    <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
    <description>The OS by PD-L1 status in UC cohort is reported. The OS estimates are adjusted for baseline ECOG, smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
  </secondary_outcome>
  <number_of_arms>23</number_of_arms>
  <enrollment type="Actual">1022</enrollment>
  <condition>Advanced Solid Tumors</condition>
  <arm_group>
    <arm_group_label>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Exploration Durvalumab 20 mg/kg (Q4W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants will receive IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion Non-SCCHN Cohort HPV positive (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with non-small-cell lung cancer (NSCLC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with hepatocellular carcinoma (HCC Total) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with advance cutaneous melanoma (ACM) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with uveal melanoma (UM) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with gastroesophageal cancer (GEC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with triple-negative breast cancer (TNBC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with pancreatic adenocarcinoma (PAC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with urothelial carcinoma (UC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with glioblastoma multiforme (GBM) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with ovarian cancer (OC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with soft- tissue sarcoma (STS) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with small-cell lung cancer (SCLC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with microsatellite instability (MSI)-high cancer will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>Participants with nasopharyngeal carcinoma (NPC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
  </arm_group>
  <intervention>
    <intervention_type>Drug</intervention_type>
    <intervention_name>MEDI4736</intervention_name>
    <description>Participants will receive IV infusion of MEDI4736 for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.</description>
    <arm_group_label>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</arm_group_label>
    <arm_group_label>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion Non-SCCHN Cohort HPV positive (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</arm_group_label>
    <arm_group_label>Exploration Durvalumab 20 mg/kg (Q4W)</arm_group_label>
    <other_name>Durvalumab</other_name>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Age 18 or older.&#xD;
&#xD;
          -  In the dose-escalation phase: histologically- or cytologically- confirmed advanced&#xD;
             solid tumor that is refractory to standard therapy and for which no standard therapy&#xD;
             exists.&#xD;
&#xD;
          -  In the dose-expansion phase: histologically- or cytologically- confirmed advanced&#xD;
             solid tumor where if an approved first-line therapy is available, participants must&#xD;
             have failed, be intolerant to, be ineligible for, or have refused&#xD;
&#xD;
          -  Eastern Cooperative Oncology Group (ECOG) status of 0 or 1.&#xD;
&#xD;
          -  Adequate organ and marrow function.&#xD;
&#xD;
          -  Participants must have at least 1 measurable lesion.&#xD;
&#xD;
          -  Available archived tumor tissue sample.&#xD;
&#xD;
          -  Willingness to provide consent for biopsy sample (dose-expansion only)&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Any prior Grade ≥ 3 immune-mediated adverse event (imAE) while receiving immunotherapy&#xD;
&#xD;
          -  Prior exposure to any anti-PD-1 or anti-PD-L1 antibody&#xD;
&#xD;
          -  Any concurrent chemotherapy, immunotherapy, biologic or hormonal therapy for cancer&#xD;
             treatment.&#xD;
&#xD;
          -  Prior treatment with immunotherapy agents including, but not limited to, tumor&#xD;
             necrosis factor receptor superfamily agonists or checkpoint inhibitors or natural&#xD;
             killer (NK) cell inhibitors.&#xD;
&#xD;
          -  Active or prior documented autoimmune disease within the past 2 years&#xD;
&#xD;
          -  History of primary immunodeficiency&#xD;
&#xD;
          -  History of organ transplant that requires use of immunosuppressives&#xD;
&#xD;
          -  Symptomatic or untreated central nervous system (CNS) metastases requiring concurrent&#xD;
             treatment&#xD;
&#xD;
          -  Other invasive malignancy within 2 years&#xD;
&#xD;
          -  Women who are pregnant or lactating&#xD;
&#xD;
          -  Uncontrolled intercurrent illness&#xD;
&#xD;
          -  Known history of tuberculosis&#xD;
&#xD;
          -  Known to be human immunodeficiency virus (HIV) positive&#xD;
&#xD;
          -  Known to be Hepatitis B or C positive (except HCC participants)&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>99 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>MedImmune, LLC</last_name>
    <affiliation>MedImmune LLC</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Scottsdale</city>
        <state>Arizona</state>
        <zip>85258</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Burbank</city>
        <state>California</state>
        <zip>91505</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Gilroy</city>
        <state>California</state>
        <zip>95020</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Los Angeles</city>
        <state>California</state>
        <zip>90025</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Los Angeles</city>
        <state>California</state>
        <zip>90095</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Orange</city>
        <state>California</state>
        <zip>92868</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Palo Alto</city>
        <state>California</state>
        <zip>94304-5826</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>San Francisco</city>
        <state>California</state>
        <zip>94115</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Whittier</city>
        <state>California</state>
        <zip>90603</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>New Haven</city>
        <state>Connecticut</state>
        <zip>06520</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Washington</city>
        <state>District of Columbia</state>
        <zip>20007</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Jacksonville</city>
        <state>Florida</state>
        <zip>32224</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Miami Beach</city>
        <state>Florida</state>
        <zip>33140</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Tampa</city>
        <state>Florida</state>
        <zip>33612</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Athens</city>
        <state>Georgia</state>
        <zip>30607</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Augusta</city>
        <state>Georgia</state>
        <zip>30912</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Chicago</city>
        <state>Illinois</state>
        <zip>60637</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Baltimore</city>
        <state>Maryland</state>
        <zip>21201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Baltimore</city>
        <state>Maryland</state>
        <zip>21231</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Boston</city>
        <state>Massachusetts</state>
        <zip>02215</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Ann Arbor</city>
        <state>Michigan</state>
        <zip>48109</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Detroit</city>
        <state>Michigan</state>
        <zip>48201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Minneapolis</city>
        <state>Minnesota</state>
        <zip>55407</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Saint Louis Park</city>
        <state>Minnesota</state>
        <zip>55416</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Billings</city>
        <state>Montana</state>
        <zip>59101</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Las Vegas</city>
        <state>Nevada</state>
        <zip>89169</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Hackensack</city>
        <state>New Jersey</state>
        <zip>07601</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Paterson</city>
        <state>New Jersey</state>
        <zip>07503</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Bronx</city>
        <state>New York</state>
        <zip>10461</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>New York</city>
        <state>New York</state>
        <zip>10065</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Chapel Hill</city>
        <state>North Carolina</state>
        <zip>27599</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Huntersville</city>
        <state>North Carolina</state>
        <zip>28078</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Cleveland</city>
        <state>Ohio</state>
        <zip>44106</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Columbus</city>
        <state>Ohio</state>
        <zip>43210</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Portland</city>
        <state>Oregon</state>
        <zip>97213</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Philadelphia</city>
        <state>Pennsylvania</state>
        <zip>19107-5097</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Pittsburgh</city>
        <state>Pennsylvania</state>
        <zip>15212</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Greenville</city>
        <state>South Carolina</state>
        <zip>29605</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Nashville</city>
        <state>Tennessee</state>
        <zip>37203</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Dallas</city>
        <state>Texas</state>
        <zip>75201</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Houston</city>
        <state>Texas</state>
        <zip>77030</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Houston</city>
        <state>Texas</state>
        <zip>77090</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>San Antonio</city>
        <state>Texas</state>
        <zip>78229</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Salt Lake City</city>
        <state>Utah</state>
        <zip>84403</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Blacksburg</city>
        <state>Virginia</state>
        <zip>24060</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Fairfax</city>
        <state>Virginia</state>
        <zip>22031</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Seattle</city>
        <state>Washington</state>
        <zip>98104</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Gent</city>
        <zip>9000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Leuven</city>
        <zip>3000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Liege</city>
        <zip>B-4000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Namur</city>
        <zip>5000</zip>
        <country>Belgium</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Ottawa</city>
        <state>Ontario</state>
        <zip>K1H 8L6</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Toronto</city>
        <state>Ontario</state>
        <zip>M5G 2M9</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Montreal</city>
        <state>Quebec</state>
        <zip>H2X 3E4</zip>
        <country>Canada</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Paris Cedex 10</city>
        <zip>75475</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Villejuif Cedex</city>
        <zip>94800</zip>
        <country>France</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Berlin</city>
        <zip>12200</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Gauting</city>
        <zip>82131</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Heidelberg</city>
        <zip>69120</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Jena</city>
        <zip>07747</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Minden</city>
        <zip>32429</zip>
        <country>Germany</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Lecce</city>
        <zip>73100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Milano</city>
        <zip>20132</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Milan</city>
        <zip>20141</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Napoli</city>
        <zip>80131</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Siena</city>
        <zip>53100</zip>
        <country>Italy</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Gwangju</city>
        <zip>61469</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Seo-Gu</city>
        <zip>49241</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Seongnam-si</city>
        <zip>13620</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Seoul</city>
        <zip>03080</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Seoul</city>
        <zip>05505</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Seoul</city>
        <zip>06351</zip>
        <country>Korea, Republic of</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Tainan</city>
        <zip>70403</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Taipei</city>
        <zip>10002</zip>
        <country>Taiwan</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>London</city>
        <zip>EC1A 7BE</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>London</city>
        <zip>SW2 6JJ</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>London</city>
        <zip>W1G 6AD</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Oxford</city>
        <zip>OX3 7LE</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location>
    <facility>
      <name>Research Site</name>
      <address>
        <city>Sutton</city>
        <zip>SM2 5PT</zip>
        <country>United Kingdom</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>Belgium</country>
    <country>Canada</country>
    <country>France</country>
    <country>Germany</country>
    <country>Italy</country>
    <country>Korea, Republic of</country>
    <country>Taiwan</country>
    <country>United Kingdom</country>
    <country>United States</country>
  </location_countries>
  <link>
    <url>https://filehosting-v2.pharmacm.com/api/Attachment/Download?tenantId=80217111&amp;amp;parentIdentifier=CD-ON-MEDI4736-1108&amp;amp;attachmentIdentifier=4cfe3393-2ef4-499b-af69-233e9ad1c75e&amp;amp;fileName=cd-on-medi4736-1108-csp-amendment-9-redacted_20201207.pdf&amp;amp;versionIdentifier=</url>
    <description>CSP amendment</description>
  </link>
  <link>
    <url>https://filehosting-v2.pharmacm.com/api/Attachment/Download?tenantId=80217111&amp;amp;parentIdentifier=CD-ON-MEDI4736-1108&amp;amp;attachmentIdentifier=b10f44de-43f5-4ffd-b0aa-5f4544600b45&amp;amp;fileName=cd-on-medi4736-1108-sap-ed-6-redacted_Redacted_20201207.pdf&amp;amp;versionIdentifier=</url>
    <description>SAP redacted</description>
  </link>
  <verification_date>April 2021</verification_date>
  <study_first_submitted>September 14, 2012</study_first_submitted>
  <study_first_submitted_qc>September 24, 2012</study_first_submitted_qc>
  <study_first_posted type="Estimate">September 26, 2012</study_first_posted>
  <results_first_submitted>February 23, 2021</results_first_submitted>
  <results_first_submitted_qc>April 20, 2021</results_first_submitted_qc>
  <results_first_posted type="Actual">May 13, 2021</results_first_posted>
  <last_update_submitted>April 20, 2021</last_update_submitted>
  <last_update_submitted_qc>April 20, 2021</last_update_submitted_qc>
  <last_update_posted type="Actual">May 13, 2021</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <keyword>Advanced solid tumors</keyword>
  <intervention_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Durvalumab</mesh_term>
  </intervention_browse>
  <provided_document_section>
    <provided_document>
      <document_type>Study Protocol</document_type>
      <document_has_protocol>Yes</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>No</document_has_sap>
      <document_date>February 4, 2016</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/62/NCT01693562/Prot_000.pdf</document_url>
    </provided_document>
    <provided_document>
      <document_type>Statistical Analysis Plan</document_type>
      <document_has_protocol>No</document_has_protocol>
      <document_has_icf>No</document_has_icf>
      <document_has_sap>Yes</document_has_sap>
      <document_date>January 12, 2017</document_date>
      <document_url>https://ClinicalTrials.gov/ProvidedDocs/62/NCT01693562/SAP_001.pdf</document_url>
    </provided_document>
  </provided_document_section>

  <clinical_results>

    <participant_flow>
      <recruitment_details>The study was conducted in Belgium, Canada, France, Germany, Italy, South Korea, Taiwan, United Kingdom, and the United States of America.</recruitment_details>
      <group_list>
        <group group_id="P1">
          <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
          <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P2">
          <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P3">
          <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P4">
          <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P5">
          <title>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P6">
          <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
          <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P7">
          <title>Exploration Durvalumab 20 mg/kg (Q4W)</title>
          <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P8">
          <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P9">
          <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P10">
          <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P11">
          <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P12">
          <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P13">
          <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P14">
          <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P15">
          <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P16">
          <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P17">
          <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P18">
          <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P19">
          <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P20">
          <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P21">
          <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P22">
          <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="P23">
          <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
      </group_list>
      <period_list>
        <period>
          <title>Escalation Phase</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="4"/>
                <participants group_id="P2" count="4"/>
                <participants group_id="P3" count="3"/>
                <participants group_id="P4" count="3"/>
                <participants group_id="P5" count="6"/>
                <participants group_id="P6" count="7"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="4"/>
                <participants group_id="P2" count="4"/>
                <participants group_id="P3" count="3"/>
                <participants group_id="P4" count="3"/>
                <participants group_id="P5" count="6"/>
                <participants group_id="P6" count="7"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
          </milestone_list>
          <drop_withdraw_reason_list>
            <drop_withdraw_reason>
              <title>Withdrawal by Subject</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="1"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="2"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Death</title>
              <participants_list>
                <participants group_id="P1" count="4"/>
                <participants group_id="P2" count="2"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="3"/>
                <participants group_id="P5" count="6"/>
                <participants group_id="P6" count="4"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Lost to Follow-up</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="1"/>
                <participants group_id="P3" count="1"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Other</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="2"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="1"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
          </drop_withdraw_reason_list>
        </period>
        <period>
          <title>Exploration Phase</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="21"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="21"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
          </milestone_list>
          <drop_withdraw_reason_list>
            <drop_withdraw_reason>
              <title>Withdrawal by Subject</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="2"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Death</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="17"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Other</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="2"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="0"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="0"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </drop_withdraw_reason>
          </drop_withdraw_reason_list>
        </period>
        <period>
          <title>Expansion Phase</title>
          <milestone_list>
            <milestone>
              <title>STARTED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="62"/>
                <participants group_id="P9" count="22"/>
                <participants group_id="P10" count="304">2 eligible NSCLC participants from dose-escalation were added to the dose expansion summaries.</participants>
                <participants group_id="P11" count="40"/>
                <participants group_id="P12" count="21"/>
                <participants group_id="P13" count="24"/>
                <participants group_id="P14" count="51"/>
                <participants group_id="P15" count="40"/>
                <participants group_id="P16" count="31"/>
                <participants group_id="P17" count="201"/>
                <participants group_id="P18" count="20"/>
                <participants group_id="P19" count="47"/>
                <participants group_id="P20" count="20"/>
                <participants group_id="P21" count="21"/>
                <participants group_id="P22" count="62"/>
                <participants group_id="P23" count="10"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="0"/>
                <participants group_id="P9" count="0"/>
                <participants group_id="P10" count="4"/>
                <participants group_id="P11" count="0"/>
                <participants group_id="P12" count="0"/>
                <participants group_id="P13" count="1"/>
                <participants group_id="P14" count="0"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="4"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="0"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="0"/>
                <participants group_id="P22" count="0"/>
                <participants group_id="P23" count="0"/>
              </participants_list>
            </milestone>
            <milestone>
              <title>NOT COMPLETED</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="62"/>
                <participants group_id="P9" count="22"/>
                <participants group_id="P10" count="300"/>
                <participants group_id="P11" count="40"/>
                <participants group_id="P12" count="21"/>
                <participants group_id="P13" count="23"/>
                <participants group_id="P14" count="51"/>
                <participants group_id="P15" count="40"/>
                <participants group_id="P16" count="31"/>
                <participants group_id="P17" count="197"/>
                <participants group_id="P18" count="20"/>
                <participants group_id="P19" count="47"/>
                <participants group_id="P20" count="20"/>
                <participants group_id="P21" count="21"/>
                <participants group_id="P22" count="62"/>
                <participants group_id="P23" count="10"/>
              </participants_list>
            </milestone>
          </milestone_list>
          <drop_withdraw_reason_list>
            <drop_withdraw_reason>
              <title>Withdrawal by Subject</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="16"/>
                <participants group_id="P9" count="2"/>
                <participants group_id="P10" count="54"/>
                <participants group_id="P11" count="2"/>
                <participants group_id="P12" count="2"/>
                <participants group_id="P13" count="3"/>
                <participants group_id="P14" count="5"/>
                <participants group_id="P15" count="16"/>
                <participants group_id="P16" count="7"/>
                <participants group_id="P17" count="40"/>
                <participants group_id="P18" count="4"/>
                <participants group_id="P19" count="8"/>
                <participants group_id="P20" count="3"/>
                <participants group_id="P21" count="1"/>
                <participants group_id="P22" count="8"/>
                <participants group_id="P23" count="1"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Death</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="42"/>
                <participants group_id="P9" count="17"/>
                <participants group_id="P10" count="208"/>
                <participants group_id="P11" count="30"/>
                <participants group_id="P12" count="8"/>
                <participants group_id="P13" count="19"/>
                <participants group_id="P14" count="42"/>
                <participants group_id="P15" count="23"/>
                <participants group_id="P16" count="23"/>
                <participants group_id="P17" count="128"/>
                <participants group_id="P18" count="16"/>
                <participants group_id="P19" count="36"/>
                <participants group_id="P20" count="16"/>
                <participants group_id="P21" count="17"/>
                <participants group_id="P22" count="35"/>
                <participants group_id="P23" count="7"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Lost to Follow-up</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="1"/>
                <participants group_id="P9" count="2"/>
                <participants group_id="P10" count="10"/>
                <participants group_id="P11" count="4"/>
                <participants group_id="P12" count="4"/>
                <participants group_id="P13" count="1"/>
                <participants group_id="P14" count="3"/>
                <participants group_id="P15" count="0"/>
                <participants group_id="P16" count="1"/>
                <participants group_id="P17" count="1"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="2"/>
                <participants group_id="P20" count="1"/>
                <participants group_id="P21" count="2"/>
                <participants group_id="P22" count="2"/>
                <participants group_id="P23" count="1"/>
              </participants_list>
            </drop_withdraw_reason>
            <drop_withdraw_reason>
              <title>Other</title>
              <participants_list>
                <participants group_id="P1" count="0"/>
                <participants group_id="P2" count="0"/>
                <participants group_id="P3" count="0"/>
                <participants group_id="P4" count="0"/>
                <participants group_id="P5" count="0"/>
                <participants group_id="P6" count="0"/>
                <participants group_id="P7" count="0"/>
                <participants group_id="P8" count="3"/>
                <participants group_id="P9" count="1"/>
                <participants group_id="P10" count="28"/>
                <participants group_id="P11" count="4"/>
                <participants group_id="P12" count="7"/>
                <participants group_id="P13" count="0"/>
                <participants group_id="P14" count="1"/>
                <participants group_id="P15" count="1"/>
                <participants group_id="P16" count="0"/>
                <participants group_id="P17" count="28"/>
                <participants group_id="P18" count="0"/>
                <participants group_id="P19" count="1"/>
                <participants group_id="P20" count="0"/>
                <participants group_id="P21" count="1"/>
                <participants group_id="P22" count="17"/>
                <participants group_id="P23" count="1"/>
              </participants_list>
            </drop_withdraw_reason>
          </drop_withdraw_reason_list>
        </period>
      </period_list>
    </participant_flow>

    <baseline>
      <population>As-treated population included all participants who received any dose of study drug.</population>
      <group_list>
        <group group_id="B1">
          <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
          <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B2">
          <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B3">
          <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B4">
          <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B5">
          <title>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B6">
          <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
          <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B7">
          <title>Exploration Durvalumab 20 mg/kg (Q4W)</title>
          <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B8">
          <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B9">
          <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B10">
          <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B11">
          <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B12">
          <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B13">
          <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B14">
          <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B15">
          <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B16">
          <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B17">
          <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B18">
          <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B19">
          <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B20">
          <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B21">
          <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B22">
          <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B23">
          <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="B24">
          <title>Total</title>
          <description>Total of all reporting groups</description>
        </group>
      </group_list>
      <analyzed_list>
        <analyzed>
          <units>Participants</units>
          <scope>Overall</scope>
          <count_list>
            <count group_id="B1" value="4"/>
            <count group_id="B2" value="4"/>
            <count group_id="B3" value="3"/>
            <count group_id="B4" value="3"/>
            <count group_id="B5" value="6"/>
            <count group_id="B6" value="7"/>
            <count group_id="B7" value="21"/>
            <count group_id="B8" value="62"/>
            <count group_id="B9" value="22"/>
            <count group_id="B10" value="304"/>
            <count group_id="B11" value="40"/>
            <count group_id="B12" value="21"/>
            <count group_id="B13" value="24"/>
            <count group_id="B14" value="51"/>
            <count group_id="B15" value="40"/>
            <count group_id="B16" value="31"/>
            <count group_id="B17" value="201"/>
            <count group_id="B18" value="20"/>
            <count group_id="B19" value="47"/>
            <count group_id="B20" value="20"/>
            <count group_id="B21" value="21"/>
            <count group_id="B22" value="62"/>
            <count group_id="B23" value="10"/>
            <count group_id="B24" value="1024"/>
          </count_list>
        </analyzed>
      </analyzed_list>
      <measure_list>
        <measure>
          <title>Age, Customized</title>
          <population>The data for this baseline measure is reported separately for each phase of the study.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <title>Escalation Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="4"/>
                    <count group_id="B2" value="4"/>
                    <count group_id="B3" value="3"/>
                    <count group_id="B4" value="3"/>
                    <count group_id="B5" value="6"/>
                    <count group_id="B6" value="7"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="27"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>18-64 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="2"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="1"/>
                    <measurement group_id="B4" value="2"/>
                    <measurement group_id="B5" value="6"/>
                    <measurement group_id="B6" value="4"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="15"/>
                  </measurement_list>
                </category>
                <category>
                  <title>65-84 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="2"/>
                    <measurement group_id="B2" value="4"/>
                    <measurement group_id="B3" value="2"/>
                    <measurement group_id="B4" value="1"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="3"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="12"/>
                  </measurement_list>
                </category>
                <category>
                  <title>85 years and above</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Exploration Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="21"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="21"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>18-64 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="12"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="12"/>
                  </measurement_list>
                </category>
                <category>
                  <title>65-84 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="9"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="9"/>
                  </measurement_list>
                </category>
                <category>
                  <title>85 years and above</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Expansion Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="62"/>
                    <count group_id="B9" value="22"/>
                    <count group_id="B10" value="304"/>
                    <count group_id="B11" value="40"/>
                    <count group_id="B12" value="21"/>
                    <count group_id="B13" value="24"/>
                    <count group_id="B14" value="51"/>
                    <count group_id="B15" value="40"/>
                    <count group_id="B16" value="31"/>
                    <count group_id="B17" value="201"/>
                    <count group_id="B18" value="20"/>
                    <count group_id="B19" value="47"/>
                    <count group_id="B20" value="20"/>
                    <count group_id="B21" value="21"/>
                    <count group_id="B22" value="62"/>
                    <count group_id="B23" value="10"/>
                    <count group_id="B24" value="976"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>18-64 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="41"/>
                    <measurement group_id="B9" value="19"/>
                    <measurement group_id="B10" value="146"/>
                    <measurement group_id="B11" value="26"/>
                    <measurement group_id="B12" value="12"/>
                    <measurement group_id="B13" value="14"/>
                    <measurement group_id="B14" value="33"/>
                    <measurement group_id="B15" value="35"/>
                    <measurement group_id="B16" value="16"/>
                    <measurement group_id="B17" value="77"/>
                    <measurement group_id="B18" value="16"/>
                    <measurement group_id="B19" value="30"/>
                    <measurement group_id="B20" value="15"/>
                    <measurement group_id="B21" value="9"/>
                    <measurement group_id="B22" value="47"/>
                    <measurement group_id="B23" value="7"/>
                    <measurement group_id="B24" value="543"/>
                  </measurement_list>
                </category>
                <category>
                  <title>65-84 years</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="20"/>
                    <measurement group_id="B9" value="3"/>
                    <measurement group_id="B10" value="156"/>
                    <measurement group_id="B11" value="14"/>
                    <measurement group_id="B12" value="9"/>
                    <measurement group_id="B13" value="10"/>
                    <measurement group_id="B14" value="18"/>
                    <measurement group_id="B15" value="5"/>
                    <measurement group_id="B16" value="15"/>
                    <measurement group_id="B17" value="122"/>
                    <measurement group_id="B18" value="4"/>
                    <measurement group_id="B19" value="16"/>
                    <measurement group_id="B20" value="5"/>
                    <measurement group_id="B21" value="12"/>
                    <measurement group_id="B22" value="15"/>
                    <measurement group_id="B23" value="3"/>
                    <measurement group_id="B24" value="427"/>
                  </measurement_list>
                </category>
                <category>
                  <title>85 years and above</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="1"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="2"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="2"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="1"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Sex: Female, Male</title>
          <population>The data for this baseline measure is reported separately for each phase of the study.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <title>Escalation Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="4"/>
                    <count group_id="B2" value="4"/>
                    <count group_id="B3" value="3"/>
                    <count group_id="B4" value="3"/>
                    <count group_id="B5" value="6"/>
                    <count group_id="B6" value="7"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="27"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Female</title>
                  <measurement_list>
                    <measurement group_id="B1" value="2"/>
                    <measurement group_id="B2" value="1"/>
                    <measurement group_id="B3" value="2"/>
                    <measurement group_id="B4" value="2"/>
                    <measurement group_id="B5" value="2"/>
                    <measurement group_id="B6" value="2"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="11"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Male</title>
                  <measurement_list>
                    <measurement group_id="B1" value="2"/>
                    <measurement group_id="B2" value="3"/>
                    <measurement group_id="B3" value="1"/>
                    <measurement group_id="B4" value="1"/>
                    <measurement group_id="B5" value="4"/>
                    <measurement group_id="B6" value="5"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Exploration Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="21"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="21"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Female</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="5"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="5"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Male</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="16"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Expansion Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="62"/>
                    <count group_id="B9" value="22"/>
                    <count group_id="B10" value="304"/>
                    <count group_id="B11" value="40"/>
                    <count group_id="B12" value="21"/>
                    <count group_id="B13" value="24"/>
                    <count group_id="B14" value="51"/>
                    <count group_id="B15" value="40"/>
                    <count group_id="B16" value="31"/>
                    <count group_id="B17" value="201"/>
                    <count group_id="B18" value="20"/>
                    <count group_id="B19" value="47"/>
                    <count group_id="B20" value="20"/>
                    <count group_id="B21" value="21"/>
                    <count group_id="B22" value="62"/>
                    <count group_id="B23" value="10"/>
                    <count group_id="B24" value="976"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Female</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="9"/>
                    <measurement group_id="B9" value="15"/>
                    <measurement group_id="B10" value="133"/>
                    <measurement group_id="B11" value="8"/>
                    <measurement group_id="B12" value="9"/>
                    <measurement group_id="B13" value="10"/>
                    <measurement group_id="B14" value="13"/>
                    <measurement group_id="B15" value="40"/>
                    <measurement group_id="B16" value="9"/>
                    <measurement group_id="B17" value="58"/>
                    <measurement group_id="B18" value="7"/>
                    <measurement group_id="B19" value="47"/>
                    <measurement group_id="B20" value="15"/>
                    <measurement group_id="B21" value="8"/>
                    <measurement group_id="B22" value="34"/>
                    <measurement group_id="B23" value="3"/>
                    <measurement group_id="B24" value="418"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Male</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="53"/>
                    <measurement group_id="B9" value="7"/>
                    <measurement group_id="B10" value="171"/>
                    <measurement group_id="B11" value="32"/>
                    <measurement group_id="B12" value="12"/>
                    <measurement group_id="B13" value="14"/>
                    <measurement group_id="B14" value="38"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="22"/>
                    <measurement group_id="B17" value="143"/>
                    <measurement group_id="B18" value="13"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="5"/>
                    <measurement group_id="B21" value="13"/>
                    <measurement group_id="B22" value="28"/>
                    <measurement group_id="B23" value="7"/>
                    <measurement group_id="B24" value="558"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Ethnicity (NIH/OMB)</title>
          <population>The data for this baseline measure is reported separately for each phase of the study.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <title>Escalation Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="4"/>
                    <count group_id="B2" value="4"/>
                    <count group_id="B3" value="3"/>
                    <count group_id="B4" value="3"/>
                    <count group_id="B5" value="6"/>
                    <count group_id="B6" value="7"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="27"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="1"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="1"/>
                    <measurement group_id="B6" value="1"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="3"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Not Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="3"/>
                    <measurement group_id="B2" value="4"/>
                    <measurement group_id="B3" value="2"/>
                    <measurement group_id="B4" value="3"/>
                    <measurement group_id="B5" value="5"/>
                    <measurement group_id="B6" value="6"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="23"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Unknown or Not Reported</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="1"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Exploration Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="21"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="21"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="2"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="2"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Not Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="19"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="19"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Unknown or Not Reported</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Expansion Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="62"/>
                    <count group_id="B9" value="22"/>
                    <count group_id="B10" value="304"/>
                    <count group_id="B11" value="40"/>
                    <count group_id="B12" value="21"/>
                    <count group_id="B13" value="24"/>
                    <count group_id="B14" value="51"/>
                    <count group_id="B15" value="40"/>
                    <count group_id="B16" value="31"/>
                    <count group_id="B17" value="201"/>
                    <count group_id="B18" value="20"/>
                    <count group_id="B19" value="47"/>
                    <count group_id="B20" value="20"/>
                    <count group_id="B21" value="21"/>
                    <count group_id="B22" value="62"/>
                    <count group_id="B23" value="10"/>
                    <count group_id="B24" value="976"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="5"/>
                    <measurement group_id="B9" value="1"/>
                    <measurement group_id="B10" value="12"/>
                    <measurement group_id="B11" value="2"/>
                    <measurement group_id="B12" value="2"/>
                    <measurement group_id="B13" value="1"/>
                    <measurement group_id="B14" value="4"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="1"/>
                    <measurement group_id="B17" value="5"/>
                    <measurement group_id="B18" value="2"/>
                    <measurement group_id="B19" value="2"/>
                    <measurement group_id="B20" value="5"/>
                    <measurement group_id="B21" value="1"/>
                    <measurement group_id="B22" value="4"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="47"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Not Hispanic or Latino</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="54"/>
                    <measurement group_id="B9" value="21"/>
                    <measurement group_id="B10" value="287"/>
                    <measurement group_id="B11" value="32"/>
                    <measurement group_id="B12" value="19"/>
                    <measurement group_id="B13" value="18"/>
                    <measurement group_id="B14" value="43"/>
                    <measurement group_id="B15" value="33"/>
                    <measurement group_id="B16" value="30"/>
                    <measurement group_id="B17" value="177"/>
                    <measurement group_id="B18" value="18"/>
                    <measurement group_id="B19" value="39"/>
                    <measurement group_id="B20" value="15"/>
                    <measurement group_id="B21" value="20"/>
                    <measurement group_id="B22" value="42"/>
                    <measurement group_id="B23" value="10"/>
                    <measurement group_id="B24" value="858"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Unknown or Not Reported</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="3"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="5"/>
                    <measurement group_id="B11" value="6"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="5"/>
                    <measurement group_id="B14" value="4"/>
                    <measurement group_id="B15" value="7"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="19"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="6"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="16"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="71"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <measure>
          <title>Race/Ethnicity, Customized</title>
          <population>The data for this baseline measure is reported separately for each phase of the study.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <class_list>
            <class>
              <title>Escalation Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="4"/>
                    <count group_id="B2" value="4"/>
                    <count group_id="B3" value="3"/>
                    <count group_id="B4" value="3"/>
                    <count group_id="B5" value="6"/>
                    <count group_id="B6" value="7"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="27"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>American Indian or Alaskan Native</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Asian</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="1"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="1"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Black or African American</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="1"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="1"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Native Hawaiian or Other Pacific Islander</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>White</title>
                  <measurement_list>
                    <measurement group_id="B1" value="4"/>
                    <measurement group_id="B2" value="3"/>
                    <measurement group_id="B3" value="2"/>
                    <measurement group_id="B4" value="2"/>
                    <measurement group_id="B5" value="6"/>
                    <measurement group_id="B6" value="7"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="24"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Other</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Multiple</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Missing</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="1"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Exploration Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="21"/>
                    <count group_id="B8" value="0"/>
                    <count group_id="B9" value="0"/>
                    <count group_id="B10" value="0"/>
                    <count group_id="B11" value="0"/>
                    <count group_id="B12" value="0"/>
                    <count group_id="B13" value="0"/>
                    <count group_id="B14" value="0"/>
                    <count group_id="B15" value="0"/>
                    <count group_id="B16" value="0"/>
                    <count group_id="B17" value="0"/>
                    <count group_id="B18" value="0"/>
                    <count group_id="B19" value="0"/>
                    <count group_id="B20" value="0"/>
                    <count group_id="B21" value="0"/>
                    <count group_id="B22" value="0"/>
                    <count group_id="B23" value="0"/>
                    <count group_id="B24" value="21"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>American Indian or Alaskan Native</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Asian</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Black or African American</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="1"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="1"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Native Hawaiian or Other Pacific Islander</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>White</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="19"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="19"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Other</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="1"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="1"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Multiple</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Missing</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Expansion Phase</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="B1" value="0"/>
                    <count group_id="B2" value="0"/>
                    <count group_id="B3" value="0"/>
                    <count group_id="B4" value="0"/>
                    <count group_id="B5" value="0"/>
                    <count group_id="B6" value="0"/>
                    <count group_id="B7" value="0"/>
                    <count group_id="B8" value="62"/>
                    <count group_id="B9" value="22"/>
                    <count group_id="B10" value="304"/>
                    <count group_id="B11" value="40"/>
                    <count group_id="B12" value="21"/>
                    <count group_id="B13" value="24"/>
                    <count group_id="B14" value="51"/>
                    <count group_id="B15" value="40"/>
                    <count group_id="B16" value="31"/>
                    <count group_id="B17" value="201"/>
                    <count group_id="B18" value="20"/>
                    <count group_id="B19" value="47"/>
                    <count group_id="B20" value="20"/>
                    <count group_id="B21" value="21"/>
                    <count group_id="B22" value="62"/>
                    <count group_id="B23" value="10"/>
                    <count group_id="B24" value="976"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <title>American Indian or Alaskan Native</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="0"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Asian</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="5"/>
                    <measurement group_id="B9" value="1"/>
                    <measurement group_id="B10" value="58"/>
                    <measurement group_id="B11" value="9"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="1"/>
                    <measurement group_id="B15" value="2"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="40"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="4"/>
                    <measurement group_id="B20" value="1"/>
                    <measurement group_id="B21" value="2"/>
                    <measurement group_id="B22" value="6"/>
                    <measurement group_id="B23" value="5"/>
                    <measurement group_id="B24" value="134"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Black or African American</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="1"/>
                    <measurement group_id="B9" value="2"/>
                    <measurement group_id="B10" value="10"/>
                    <measurement group_id="B11" value="3"/>
                    <measurement group_id="B12" value="1"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="1"/>
                    <measurement group_id="B15" value="6"/>
                    <measurement group_id="B16" value="1"/>
                    <measurement group_id="B17" value="8"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="1"/>
                    <measurement group_id="B20" value="1"/>
                    <measurement group_id="B21" value="1"/>
                    <measurement group_id="B22" value="2"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="38"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Native Hawaiian or Other Pacific Islander</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="1"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="2"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="0"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="2"/>
                    <measurement group_id="B24" value="5"/>
                  </measurement_list>
                </category>
                <category>
                  <title>White</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="49"/>
                    <measurement group_id="B9" value="19"/>
                    <measurement group_id="B10" value="227"/>
                    <measurement group_id="B11" value="19"/>
                    <measurement group_id="B12" value="19"/>
                    <measurement group_id="B13" value="19"/>
                    <measurement group_id="B14" value="45"/>
                    <measurement group_id="B15" value="25"/>
                    <measurement group_id="B16" value="29"/>
                    <measurement group_id="B17" value="128"/>
                    <measurement group_id="B18" value="19"/>
                    <measurement group_id="B19" value="36"/>
                    <measurement group_id="B20" value="18"/>
                    <measurement group_id="B21" value="17"/>
                    <measurement group_id="B22" value="34"/>
                    <measurement group_id="B23" value="3"/>
                    <measurement group_id="B24" value="706"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Other</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="2"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="4"/>
                    <measurement group_id="B11" value="1"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="0"/>
                    <measurement group_id="B15" value="1"/>
                    <measurement group_id="B16" value="1"/>
                    <measurement group_id="B17" value="5"/>
                    <measurement group_id="B18" value="1"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="1"/>
                    <measurement group_id="B22" value="4"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="20"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Multiple</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="0"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="0"/>
                    <measurement group_id="B11" value="0"/>
                    <measurement group_id="B12" value="0"/>
                    <measurement group_id="B13" value="0"/>
                    <measurement group_id="B14" value="1"/>
                    <measurement group_id="B15" value="0"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="1"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="0"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="0"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="2"/>
                  </measurement_list>
                </category>
                <category>
                  <title>Missing</title>
                  <measurement_list>
                    <measurement group_id="B1" value="0"/>
                    <measurement group_id="B2" value="0"/>
                    <measurement group_id="B3" value="0"/>
                    <measurement group_id="B4" value="0"/>
                    <measurement group_id="B5" value="0"/>
                    <measurement group_id="B6" value="0"/>
                    <measurement group_id="B7" value="0"/>
                    <measurement group_id="B8" value="4"/>
                    <measurement group_id="B9" value="0"/>
                    <measurement group_id="B10" value="5"/>
                    <measurement group_id="B11" value="6"/>
                    <measurement group_id="B12" value="1"/>
                    <measurement group_id="B13" value="5"/>
                    <measurement group_id="B14" value="3"/>
                    <measurement group_id="B15" value="6"/>
                    <measurement group_id="B16" value="0"/>
                    <measurement group_id="B17" value="19"/>
                    <measurement group_id="B18" value="0"/>
                    <measurement group_id="B19" value="6"/>
                    <measurement group_id="B20" value="0"/>
                    <measurement group_id="B21" value="0"/>
                    <measurement group_id="B22" value="16"/>
                    <measurement group_id="B23" value="0"/>
                    <measurement group_id="B24" value="71"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </measure_list>
    </baseline>

    <outcome_list>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Dose-limiting Toxicities in the Dose-escalation Phase</title>
        <description>A DLT was defined as any Grade 3 or higher treatment-related toxicity that occurred during the DLT-evaluation period including any &gt;= Grade 3 colitis or &gt;= Grade 3 immune-related adverse event (irAE; AEs of immune nature in the absence of a clear alternative etiology) including rash, pruritus, or diarrhea that did not downgrade to =&lt; Grade 2 within 3 days after onset of the event despite maximal supportive care including systemic corticosteroids. The DLT-evaluation period for 0.1 to 10 mg/kg arms was from Day 1 to Day 28 of first dose and for 15 mg/kg arm was from Day 1 to Day 42 of first dose.</description>
        <time_frame>For MEDI4736 0.1 to MEDI4736 10 mg/kg arms: from Day 1 to Day 28 of first dose; for MEDI4736 15 mg/kg arm: from Day 1 to Day 42 of first dose</time_frame>
        <population>DLT-evaluable population included all participants in the dose-escalation phase who received at least 2 doses of study drug and completed safety follow-up through DLT-evaluable period or experienced any DLT during the DLT-evaluation period.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Dose-limiting Toxicities in the Dose-escalation Phase</title>
          <description>A DLT was defined as any Grade 3 or higher treatment-related toxicity that occurred during the DLT-evaluation period including any &gt;= Grade 3 colitis or &gt;= Grade 3 immune-related adverse event (irAE; AEs of immune nature in the absence of a clear alternative etiology) including rash, pruritus, or diarrhea that did not downgrade to =&lt; Grade 2 within 3 days after onset of the event despite maximal supportive care including systemic corticosteroids. The DLT-evaluation period for 0.1 to 10 mg/kg arms was from Day 1 to Day 28 of first dose and for 15 mg/kg arm was from Day 1 to Day 42 of first dose.</description>
          <population>DLT-evaluable population included all participants in the dose-escalation phase who received at least 2 doses of study drug and completed safety follow-up through DLT-evaluable period or experienced any DLT during the DLT-evaluation period.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="6"/>
                <count group_id="O6" value="7"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs) in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
        <description>An adverse event (AE) is any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship. A serious adverse event (SAE) is an AE resulting in any of the following outcomes or deemed significant for any other reason: death; initial or prolonged inpatient hospitalization; life threatening experience (immediate risk of dying); persistent or significant disability/incapacity; congenital anomaly. The TEAEs are defined as events present at baseline that worsened in intensity after administration of study drug or events absent at baseline that emerged after administration of study drug.</description>
        <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-programmed cell death ligand (PD-L1/PD-1) drug class.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Exploration Cohort (MEDI4736 20 mg/kg Q4W)</title>
            <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Escalation/Expansion Cohort (Total MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation or dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs) in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
          <description>An adverse event (AE) is any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship. A serious adverse event (SAE) is an AE resulting in any of the following outcomes or deemed significant for any other reason: death; initial or prolonged inpatient hospitalization; life threatening experience (immediate risk of dying); persistent or significant disability/incapacity; congenital anomaly. The TEAEs are defined as events present at baseline that worsened in intensity after administration of study drug or events absent at baseline that emerged after administration of study drug.</description>
          <population>As-treated population included all participants who received any dose of study drug. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-programmed cell death ligand (PD-L1/PD-1) drug class.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="7"/>
                <count group_id="O6" value="21"/>
                <count group_id="O7" value="980"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Any TEAEs</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="3"/>
                    <measurement group_id="O2" value="4"/>
                    <measurement group_id="O3" value="3"/>
                    <measurement group_id="O4" value="3"/>
                    <measurement group_id="O5" value="7"/>
                    <measurement group_id="O6" value="21"/>
                    <measurement group_id="O7" value="963"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Any TESAEs</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="2"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="1"/>
                    <measurement group_id="O5" value="3"/>
                    <measurement group_id="O6" value="13"/>
                    <measurement group_id="O7" value="536"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Abnormal Clinical Laboratory Parameters Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
        <description>Number of participants with abnormal clinical laboratory parameters reported as TEAEs are reported. Abnormal clinical laboratory parameters defined as any abnormal finding during analysis of coagulation, urine, hematology, and serum chemistry.</description>
        <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-PD-L1/PD-1 drug class.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Exploration Cohort (MEDI4736 20 mg/kg Q4W)</title>
            <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Escalation/Expansion Cohort (Total MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation or dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Abnormal Clinical Laboratory Parameters Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
          <description>Number of participants with abnormal clinical laboratory parameters reported as TEAEs are reported. Abnormal clinical laboratory parameters defined as any abnormal finding during analysis of coagulation, urine, hematology, and serum chemistry.</description>
          <population>As-treated population included all participants who received any dose of study drug. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-PD-L1/PD-1 drug class.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="7"/>
                <count group_id="O6" value="21"/>
                <count group_id="O7" value="980"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Anaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="166"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Thrombocytopenia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="24"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>White blood cell count increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukocytosis</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="20"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphocyte count decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="12"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutropenia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukopenia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Thrombocytosis</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Iron deficiency anaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Haemoglobin decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil count increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Red blood cell count decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Anaemia of chronic disease</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Eosinophilia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Haemolysis</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Leukostasis syndrome</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Immune thrombocytopenic purpura</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>International normalised ratio increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Activated partial thromboplastin time prolonged</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="15"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood fibrinogen increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Platelet count decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Disseminated intravascular coagulation</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Prothrombin time prolonged</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Activated partial thromboplastin time shortened</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Coagulation factor increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Coagulopathy</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine aminotransferase increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="2"/>
                    <measurement group_id="O7" value="77"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate aminotransferase increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="2"/>
                    <measurement group_id="O7" value="99"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood alkaline phosphatase increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="70"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood bilirubin increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="42"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Gamma-glutamyltransferase increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="2"/>
                    <measurement group_id="O7" value="71"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyperbilirubinaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="14"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transaminases increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood lactate dehydrogenase increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hepatic function abnormal</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Alanine aminotransferase decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Aspartate aminotransferase decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood albumin decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hepatic enzyme increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Liver function test increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>White blood cell count decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Neutrophil count decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Lymphopenia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood creatinine increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="46"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyperuricaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="22"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood urea increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="10"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Glomerular filtration rate decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypothyroidism</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="3"/>
                    <measurement group_id="O7" value="89"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyperthyroidism</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="30"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood thyroid stimulating hormone increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood thyroid stimulating hormone decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Thyroxine decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Thyroxine free decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Thyroxine free increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Tri-iodothyronine free decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Thyroxine increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Tri-iodothyronine decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Tri-iodothyronine increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyponatraemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="91"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypomagnesaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="55"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypercalcaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="47"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyperglycaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="32"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypokalaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="60"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypocalcaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypophosphataemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="16"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypertriglyceridaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="13"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypoglycaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="10"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood cholesterol increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood magnesium decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood triglycerides increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood glucose increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypercholesterolaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood potassium increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood chloride increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood electrolytes decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood potassium decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyperphosphataemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Protein total decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Protein urine present</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood bicarbonate decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood chloride decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Blood sodium decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypermagnesaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypernatraemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypochloraemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypoproteinaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hyperkalaemia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="30"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Abnormal Vital Signs Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
        <description>Number of participants with abnormal vital signs reported as TEAEs are reported. Abnormal vital signs are defined as any abnormal finding in the vital sign parameters (body weight, body temperature, blood pressure, pulse rate, and respiratory rate).</description>
        <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-PD-L1/PD-1 drug class.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Exploration Cohort (MEDI4736 20 mg/kg Q4W)</title>
            <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Escalation/Expansion Cohort (Total MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation or dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Abnormal Vital Signs Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
          <description>Number of participants with abnormal vital signs reported as TEAEs are reported. Abnormal vital signs are defined as any abnormal finding in the vital sign parameters (body weight, body temperature, blood pressure, pulse rate, and respiratory rate).</description>
          <population>As-treated population included all participants who received any dose of study drug. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-PD-L1/PD-1 drug class.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="7"/>
                <count group_id="O6" value="21"/>
                <count group_id="O7" value="980"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Pyrexia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="3"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="1"/>
                    <measurement group_id="O5" value="3"/>
                    <measurement group_id="O6" value="2"/>
                    <measurement group_id="O7" value="145"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Weight decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="2"/>
                    <measurement group_id="O7" value="79"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypertension</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="1"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="31"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Hypotension</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="36"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Weight increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="22"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Tachycardia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="19"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sinus tachycardia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="14"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Arrhythmia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Sinus bradycardia</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Heart rate increased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Heart rate irregular</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Peak expiratory flow rate decreased</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Number of Participants With Change From Baseline in QT/QTc Interval in Local Electrocardiogram in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
        <description>Number of participants with change from baseline in notable QT/QTc interval in local electrocardiogram (ECG) are reported. The data for &gt;0 participants with notable QT/QTc interval in local ECG from baseline are reported.</description>
        <time_frame>From Baseline (Day 1) through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug were analyzed. Participants with ECG readings available were evaluable for this analysis. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-PD-L1/PD-1 drug class.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Exploration Cohort (MEDI4736 20 mg/kg Q4W)</title>
            <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Escalation/Expansion Cohort (Total MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation or dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Change From Baseline in QT/QTc Interval in Local Electrocardiogram in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
          <description>Number of participants with change from baseline in notable QT/QTc interval in local electrocardiogram (ECG) are reported. The data for &gt;0 participants with notable QT/QTc interval in local ECG from baseline are reported.</description>
          <population>As-treated population included all participants who received any dose of study drug were analyzed. Participants with ECG readings available were evaluable for this analysis. Participants enrolled in the 10 mg/kg Q2W Expansion and Escalation Cohort have been summarized as a total only. This is because the safety profile of durvalumab monotherapy 10 mg/kg Q2W was manageable and generally consistent with the known safety profile of the anti-PD-L1/PD-1 drug class.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="7"/>
                <count group_id="O6" value="21"/>
                <count group_id="O7" value="980"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>QTcF: &gt; 30 (msec)</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                    <count group_id="O7" value="63"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O7" value="4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcF: &gt; 60 (msec)</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="0"/>
                    <count group_id="O2" value="1"/>
                    <count group_id="O3" value="1"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="0"/>
                    <count group_id="O6" value="0"/>
                    <count group_id="O7" value="63"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O7" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcB: &gt; 30 (msec)</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="2"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="2"/>
                    <count group_id="O6" value="9"/>
                    <count group_id="O7" value="288"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="4"/>
                    <measurement group_id="O7" value="17"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcB: &gt; 60 (msec)</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="2"/>
                    <count group_id="O2" value="2"/>
                    <count group_id="O3" value="2"/>
                    <count group_id="O4" value="1"/>
                    <count group_id="O5" value="2"/>
                    <count group_id="O6" value="9"/>
                    <count group_id="O7" value="288"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>QTcB: &gt; 90 (msec)</title>
              <analyzed_list>
                <analyzed>
                  <units>Participants</units>
                  <scope>Class</scope>
                  <count_list>
                    <count group_id="O1" value="4"/>
                    <count group_id="O2" value="4"/>
                    <count group_id="O3" value="3"/>
                    <count group_id="O4" value="3"/>
                    <count group_id="O5" value="7"/>
                    <count group_id="O6" value="21"/>
                    <count group_id="O7" value="288"/>
                  </count_list>
                </analyzed>
              </analyzed_list>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>Objective Response Rate (ORR) Assessed by Blinded Independent Central Review (BICR) in Participants With Non-squamous NSCLC Who Had Received 2 or More Prior Lines of Therapy in the Dose-expansion Phase</title>
        <description>The ORR assessed by BICR in participants with non-squamous NSCLC who had received 2 or more prior lines of therapy is reported. The ORR is defined as best overall response (BOR) of confirmed complete response (CR) or confirmed partial response (PR) based on Response Evaluation Criteria in Solid Tumours Version 1.1 (RECIST v1.1). The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants with non-squamous NSCLC in Full analysis set (FAS) population who had received 2 or more prior line of therapy were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion Non-squamous NSCLC 3L+ Cohort</title>
            <description>Participants with non-squamous NSCLC who had received 2 or more lines of prior therapy (3L+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Objective Response Rate (ORR) Assessed by Blinded Independent Central Review (BICR) in Participants With Non-squamous NSCLC Who Had Received 2 or More Prior Lines of Therapy in the Dose-expansion Phase</title>
          <description>The ORR assessed by BICR in participants with non-squamous NSCLC who had received 2 or more prior lines of therapy is reported. The ORR is defined as best overall response (BOR) of confirmed complete response (CR) or confirmed partial response (PR) based on Response Evaluation Criteria in Solid Tumours Version 1.1 (RECIST v1.1). The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
          <population>Participants with non-squamous NSCLC in Full analysis set (FAS) population who had received 2 or more prior line of therapy were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="68"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10.3" lower_limit="4.2" upper_limit="20.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>ORR Assessed by BICR in Participants With Squamous NSCLC Who Had Received 1 and 2 or More Prior Lines of Therapy in the Dose-expansion Phase</title>
        <description>The ORR assessed by BICR in participants with squamous NSCLC who had received 1 and 2 or more prior lines of therapy is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants with squamous NSCLC in FAS population who had received 1 and 2 or more prior lines of therapy were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion Squamous NSCLC 2L+ Cohort</title>
            <description>Participants with squamous NSCLC who had received at least 1 line of prior therapy (2L+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion Squamous NSCLC 3L+ Cohort</title>
            <description>Participants with squamous NSCLC who had received 2 or more lines of prior therapy (3L+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>ORR Assessed by BICR in Participants With Squamous NSCLC Who Had Received 1 and 2 or More Prior Lines of Therapy in the Dose-expansion Phase</title>
          <description>The ORR assessed by BICR in participants with squamous NSCLC who had received 1 and 2 or more prior lines of therapy is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
          <population>Participants with squamous NSCLC in FAS population who had received 1 and 2 or more prior lines of therapy were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="117"/>
                <count group_id="O2" value="62"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="12.8" lower_limit="7.4" upper_limit="20.3"/>
                    <measurement group_id="O2" value="12.9" lower_limit="5.7" upper_limit="23.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Primary</type>
        <title>ORR Assessed by BICR in Participants With UC Post-platinum (Programmed Cell Death Ligand [PD-L1] Status High) Who Had Received at Least 1 Line of Prior Therapy (2L+) in the Dose-expansion Phase</title>
        <description>The ORR assessed by BICR in participants with UC post-platinum PD-L1 status high 2L+ is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants with UC in FAS population with 2L+ post-platinum PD-L1 status high (&gt;= 25% tumor cell membrane or &gt;= 25% immune cell staining) were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 High 2L+ Cohort</title>
            <description>Participants with UC (post-platinum PD-L1 status high) who had received at least 1 line of prior therapy (2L+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>ORR Assessed by BICR in Participants With UC Post-platinum (Programmed Cell Death Ligand [PD-L1] Status High) Who Had Received at Least 1 Line of Prior Therapy (2L+) in the Dose-expansion Phase</title>
          <description>The ORR assessed by BICR in participants with UC post-platinum PD-L1 status high 2L+ is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
          <population>Participants with UC in FAS population with 2L+ post-platinum PD-L1 status high (&gt;= 25% tumor cell membrane or &gt;= 25% immune cell staining) were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="98"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="27.6" lower_limit="19.0" upper_limit="37.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Area Under the Serum Concentration-time Curve up to the Last Measurable Concentration (AUClast) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase</title>
        <description>Area under the concentration-time curve from time zero to the last measurable concentration (AUClast) of MEDI4736 is reported.</description>
        <time_frame>After the first dose between Day 0 and Day 15 (Day 1 [pre and post dose] and predose of Dose 2 for all cohorts; Days 3, 5, 10 for Cohorts 0.1mg/kg to 10 mg/kg; Days 3, 5, 10, 15 for Cohort 15 mg/kg; Day 15 for Cohort 20 mg/kg)</time_frame>
        <population>Pharmacokinetics (PK) evaluable population included all participants who received any dose of study drug and had at least one postdose PK concentration. Non-compartmental PK analysis was conducted using the data from dose escalation and exploration phases only. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Exploration Cohort (MEDI4736 20 mg/kg Q4W)</title>
            <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Area Under the Serum Concentration-time Curve up to the Last Measurable Concentration (AUClast) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase</title>
          <description>Area under the concentration-time curve from time zero to the last measurable concentration (AUClast) of MEDI4736 is reported.</description>
          <population>Pharmacokinetics (PK) evaluable population included all participants who received any dose of study drug and had at least one postdose PK concentration. Non-compartmental PK analysis was conducted using the data from dose escalation and exploration phases only. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Day*µg/mL</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="5"/>
                <count group_id="O6" value="7"/>
                <count group_id="O7" value="18"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.144" spread="45.1"/>
                    <measurement group_id="O2" value="25.063" spread="65.5"/>
                    <measurement group_id="O3" value="130.546" spread="20.1"/>
                    <measurement group_id="O4" value="399.863" spread="21.7"/>
                    <measurement group_id="O5" value="1780.152" spread="39.1"/>
                    <measurement group_id="O6" value="2943.770" spread="36.3"/>
                    <measurement group_id="O7" value="4501.888" spread="23.1"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Maximum Serum Concentration (Cmax) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase</title>
        <description>The Cmax of MEDI4736 is reported.</description>
        <time_frame>After the first dose between Day 0 and Day 15 (Day 1 [pre and post dose] and predose of Dose 2 for all cohorts; Days 3, 5, 10 for Cohorts 0.1mg/kg to 10 mg/kg; Days 3, 5, 10, 15 for Cohort 15 mg/kg; Day 15 for Cohort 20 mg/kg)</time_frame>
        <population>The PK evaluable population included all participants who received any dose of study drug and had at least one postdose PK concentration. Non-compartmental PK analysis was conducted using the data from dose escalation and exploration phases only. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
            <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first</description>
          </group>
          <group group_id="O3">
            <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation , whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
            <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Exploration Cohort (MEDI4736 20 mg/kg Q4W)</title>
            <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Maximum Serum Concentration (Cmax) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase</title>
          <description>The Cmax of MEDI4736 is reported.</description>
          <population>The PK evaluable population included all participants who received any dose of study drug and had at least one postdose PK concentration. Non-compartmental PK analysis was conducted using the data from dose escalation and exploration phases only. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>µg/mL</units>
          <param>Geometric Mean</param>
          <dispersion>Geometric Coefficient of Variation</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="4"/>
                <count group_id="O3" value="3"/>
                <count group_id="O4" value="3"/>
                <count group_id="O5" value="5"/>
                <count group_id="O6" value="7"/>
                <count group_id="O7" value="18"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.780" spread="22.1"/>
                    <measurement group_id="O2" value="7.969" spread="23.0"/>
                    <measurement group_id="O3" value="22.773" spread="11.3"/>
                    <measurement group_id="O4" value="70.807" spread="17.0"/>
                    <measurement group_id="O5" value="293.540" spread="23.4"/>
                    <measurement group_id="O6" value="427.085" spread="25.5"/>
                    <measurement group_id="O7" value="416.051" spread="23.9"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Number of Participants With Positive Anti-drug Antibodies (ADA) to MEDI4736 in the Dose-escalation, Dose-exploration Phase, and Dose-expansion Phase.</title>
        <description>Number of participants with positive ADA titer to MEDI4736 are reported. Treatment-boosted ADA is defined as baseline positive ADA titer that was boosted to a 4-fold or higher level following drug administration; persistent positive is defined as positive at &gt;= 2 post-baseline assessments (with &gt;= 16 weeks between first and last positive) or positive at last post-baseline assessment; and transient positive is defined as having at least one post-baseline ADA-positive assessment and not fulfilling the condition of persistent positive.</description>
        <time_frame>Escalation: Day1 of Dose(D)1 &amp; D3, even numbered doses after D4; Exploration: Day1 of D1 &amp; D2, even numbered doses after D2; Expansion: Day1 of D1, every 12 weeks since D3; all phases: till EOT, 30 days and 3 and 6 months post last dose (~5.25 years)</time_frame>
        <population>The ADA evaluable population included all participants who received any dose of study drug, had non-missing baseline (before Day 1) ADA, and at least one non-missing post-baseline ADA results. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Total Escalation/Exploration Cohort</title>
            <description>Participants received IV infusion of MEDI4736 0.1 mg/kg, 0.3 mg/kg, 1 mg/kg, 3 mg/kg, and 10 mg/kg Q2W, and 15 mg/kg Q3W in the dose-escalation phase; and 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O8">
            <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O9">
            <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O10">
            <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O11">
            <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O12">
            <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O13">
            <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O14">
            <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O15">
            <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O16">
            <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O17">
            <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Positive Anti-drug Antibodies (ADA) to MEDI4736 in the Dose-escalation, Dose-exploration Phase, and Dose-expansion Phase.</title>
          <description>Number of participants with positive ADA titer to MEDI4736 are reported. Treatment-boosted ADA is defined as baseline positive ADA titer that was boosted to a 4-fold or higher level following drug administration; persistent positive is defined as positive at &gt;= 2 post-baseline assessments (with &gt;= 16 weeks between first and last positive) or positive at last post-baseline assessment; and transient positive is defined as having at least one post-baseline ADA-positive assessment and not fulfilling the condition of persistent positive.</description>
          <population>The ADA evaluable population included all participants who received any dose of study drug, had non-missing baseline (before Day 1) ADA, and at least one non-missing post-baseline ADA results. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="45"/>
                <count group_id="O2" value="56"/>
                <count group_id="O3" value="17"/>
                <count group_id="O4" value="257"/>
                <count group_id="O5" value="37"/>
                <count group_id="O6" value="17"/>
                <count group_id="O7" value="21"/>
                <count group_id="O8" value="38"/>
                <count group_id="O9" value="33"/>
                <count group_id="O10" value="26"/>
                <count group_id="O11" value="148"/>
                <count group_id="O12" value="17"/>
                <count group_id="O13" value="41"/>
                <count group_id="O14" value="19"/>
                <count group_id="O15" value="15"/>
                <count group_id="O16" value="58"/>
                <count group_id="O17" value="6"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>Positive post-baseline</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4"/>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="6"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                    <measurement group_id="O8" value="0"/>
                    <measurement group_id="O9" value="1"/>
                    <measurement group_id="O10" value="0"/>
                    <measurement group_id="O11" value="7"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="2"/>
                    <measurement group_id="O14" value="1"/>
                    <measurement group_id="O15" value="0"/>
                    <measurement group_id="O16" value="2"/>
                    <measurement group_id="O17" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Treatment-boosted</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="0"/>
                    <measurement group_id="O8" value="0"/>
                    <measurement group_id="O9" value="0"/>
                    <measurement group_id="O10" value="0"/>
                    <measurement group_id="O11" value="1"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="0"/>
                    <measurement group_id="O14" value="0"/>
                    <measurement group_id="O15" value="0"/>
                    <measurement group_id="O16" value="0"/>
                    <measurement group_id="O17" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Persistent positive</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2"/>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="4"/>
                    <measurement group_id="O5" value="1"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="1"/>
                    <measurement group_id="O8" value="0"/>
                    <measurement group_id="O9" value="1"/>
                    <measurement group_id="O10" value="1"/>
                    <measurement group_id="O11" value="5"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="0"/>
                    <measurement group_id="O14" value="1"/>
                    <measurement group_id="O15" value="0"/>
                    <measurement group_id="O16" value="1"/>
                    <measurement group_id="O17" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Transient positive</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="0"/>
                    <measurement group_id="O4" value="2"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="0"/>
                    <measurement group_id="O8" value="0"/>
                    <measurement group_id="O9" value="0"/>
                    <measurement group_id="O10" value="0"/>
                    <measurement group_id="O11" value="3"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="2"/>
                    <measurement group_id="O14" value="0"/>
                    <measurement group_id="O15" value="0"/>
                    <measurement group_id="O16" value="1"/>
                    <measurement group_id="O17" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Number of Participants With Best Overall Response (BOR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</title>
        <description>The BOR assessed by BICR based on RECIST v1.1 in NSCLC and SCCHN cohorts is reported. The BOR includes CR, PR, stable disease (SD), progressive disease (PD), and non-evaluable (NE). The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants in FAS population with NSCLC and SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with SCCHN received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with NSCLC received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With Best Overall Response (BOR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</title>
          <description>The BOR assessed by BICR based on RECIST v1.1 in NSCLC and SCCHN cohorts is reported. The BOR includes CR, PR, stable disease (SD), progressive disease (PD), and non-evaluable (NE). The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.</description>
          <population>Participants in FAS population with NSCLC and SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="55"/>
                <count group_id="O2" value="275"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>CR</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4"/>
                    <measurement group_id="O2" value="39"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SD</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10"/>
                    <measurement group_id="O2" value="80"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PD</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="31"/>
                    <measurement group_id="O2" value="110"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>NE</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="10"/>
                    <measurement group_id="O2" value="43"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Number of Participants With BOR Assessed by Investigator in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
        <description>The BOR assessed by investigator based on RECIST v1.1 is reported. The BOR includes CR, PR, SD, PD, and NE. The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure. One participant from non-SCCHN HPV positive cohort had non-evaluable disease at baseline.</population>
        <group_list>
          <group group_id="O1">
            <title>Total Escalation/Exploration Cohort</title>
            <description>Participants received IV infusion of MEDI4736 0.1 mg/kg, 0.3 mg/kg, 1 mg/kg, 3 mg/kg, and 10 mg/kg Q2W, and 15 mg/kg Q3W in the dose-escalation phase; and 20 mg/kg Q4W in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O8">
            <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O9">
            <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O10">
            <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O11">
            <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O12">
            <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O13">
            <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O14">
            <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O15">
            <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O16">
            <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O17">
            <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Number of Participants With BOR Assessed by Investigator in the Dose-escalation, Dose-exploration, and Dose-expansion Phase</title>
          <description>The BOR assessed by investigator based on RECIST v1.1 is reported. The BOR includes CR, PR, SD, PD, and NE. The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.</description>
          <population>As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure. One participant from non-SCCHN HPV positive cohort had non-evaluable disease at baseline.</population>
          <units>Participants</units>
          <param>Count of Participants</param>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="48"/>
                <count group_id="O2" value="62"/>
                <count group_id="O3" value="22"/>
                <count group_id="O4" value="302"/>
                <count group_id="O5" value="40"/>
                <count group_id="O6" value="21"/>
                <count group_id="O7" value="24"/>
                <count group_id="O8" value="51"/>
                <count group_id="O9" value="40"/>
                <count group_id="O10" value="31"/>
                <count group_id="O11" value="201"/>
                <count group_id="O12" value="20"/>
                <count group_id="O13" value="47"/>
                <count group_id="O14" value="20"/>
                <count group_id="O15" value="21"/>
                <count group_id="O16" value="62"/>
                <count group_id="O17" value="10"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <title>CR</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1"/>
                    <measurement group_id="O2" value="1"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="5"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="1"/>
                    <measurement group_id="O7" value="0"/>
                    <measurement group_id="O8" value="1"/>
                    <measurement group_id="O9" value="0"/>
                    <measurement group_id="O10" value="0"/>
                    <measurement group_id="O11" value="18"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="1"/>
                    <measurement group_id="O14" value="0"/>
                    <measurement group_id="O15" value="0"/>
                    <measurement group_id="O16" value="3"/>
                    <measurement group_id="O17" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PR</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4"/>
                    <measurement group_id="O2" value="6"/>
                    <measurement group_id="O3" value="2"/>
                    <measurement group_id="O4" value="49"/>
                    <measurement group_id="O5" value="4"/>
                    <measurement group_id="O6" value="2"/>
                    <measurement group_id="O7" value="1"/>
                    <measurement group_id="O8" value="1"/>
                    <measurement group_id="O9" value="1"/>
                    <measurement group_id="O10" value="1"/>
                    <measurement group_id="O11" value="24"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="2"/>
                    <measurement group_id="O14" value="2"/>
                    <measurement group_id="O15" value="2"/>
                    <measurement group_id="O16" value="12"/>
                    <measurement group_id="O17" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>SD</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="18"/>
                    <measurement group_id="O2" value="14"/>
                    <measurement group_id="O3" value="7"/>
                    <measurement group_id="O4" value="102"/>
                    <measurement group_id="O5" value="22"/>
                    <measurement group_id="O6" value="9"/>
                    <measurement group_id="O7" value="8"/>
                    <measurement group_id="O8" value="17"/>
                    <measurement group_id="O9" value="8"/>
                    <measurement group_id="O10" value="6"/>
                    <measurement group_id="O11" value="45"/>
                    <measurement group_id="O12" value="5"/>
                    <measurement group_id="O13" value="18"/>
                    <measurement group_id="O14" value="8"/>
                    <measurement group_id="O15" value="4"/>
                    <measurement group_id="O16" value="27"/>
                    <measurement group_id="O17" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>PD</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="18"/>
                    <measurement group_id="O2" value="33"/>
                    <measurement group_id="O3" value="9"/>
                    <measurement group_id="O4" value="103"/>
                    <measurement group_id="O5" value="12"/>
                    <measurement group_id="O6" value="5"/>
                    <measurement group_id="O7" value="12"/>
                    <measurement group_id="O8" value="21"/>
                    <measurement group_id="O9" value="25"/>
                    <measurement group_id="O10" value="17"/>
                    <measurement group_id="O11" value="81"/>
                    <measurement group_id="O12" value="14"/>
                    <measurement group_id="O13" value="22"/>
                    <measurement group_id="O14" value="8"/>
                    <measurement group_id="O15" value="9"/>
                    <measurement group_id="O16" value="15"/>
                    <measurement group_id="O17" value="3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>NE</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7"/>
                    <measurement group_id="O2" value="8"/>
                    <measurement group_id="O3" value="2"/>
                    <measurement group_id="O4" value="43"/>
                    <measurement group_id="O5" value="2"/>
                    <measurement group_id="O6" value="4"/>
                    <measurement group_id="O7" value="3"/>
                    <measurement group_id="O8" value="11"/>
                    <measurement group_id="O9" value="6"/>
                    <measurement group_id="O10" value="7"/>
                    <measurement group_id="O11" value="33"/>
                    <measurement group_id="O12" value="1"/>
                    <measurement group_id="O13" value="4"/>
                    <measurement group_id="O14" value="2"/>
                    <measurement group_id="O15" value="6"/>
                    <measurement group_id="O16" value="5"/>
                    <measurement group_id="O17" value="2"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
            <class>
              <title>Not applicable</title>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="0"/>
                    <measurement group_id="O2" value="0"/>
                    <measurement group_id="O3" value="1"/>
                    <measurement group_id="O4" value="0"/>
                    <measurement group_id="O5" value="0"/>
                    <measurement group_id="O6" value="0"/>
                    <measurement group_id="O7" value="0"/>
                    <measurement group_id="O8" value="0"/>
                    <measurement group_id="O9" value="0"/>
                    <measurement group_id="O10" value="0"/>
                    <measurement group_id="O11" value="0"/>
                    <measurement group_id="O12" value="0"/>
                    <measurement group_id="O13" value="0"/>
                    <measurement group_id="O14" value="0"/>
                    <measurement group_id="O15" value="0"/>
                    <measurement group_id="O16" value="0"/>
                    <measurement group_id="O17" value="0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Duration of Response (DoR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</title>
        <description>The DoR assessed by BICR in NSCLC and SCCHN cohorts is reported. The DoR is defined as the duration from the first documentation of objective response (OR) (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants in FAS population with NSCLC and SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017. The DoR was analyzed for those participants who achieved OR.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous SCCHN received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with NSCLC received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Duration of Response (DoR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</title>
          <description>The DoR assessed by BICR in NSCLC and SCCHN cohorts is reported. The DoR is defined as the duration from the first documentation of objective response (OR) (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
          <population>Participants in FAS population with NSCLC and SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017. The DoR was analyzed for those participants who achieved OR.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="4"/>
                <count group_id="O2" value="42"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="12.37" lower_limit="3.5" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O2" value="17.74" lower_limit="5.6" upper_limit="38.0"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>DoR Assessed by Investigator in the Dose-expansion Phase</title>
        <description>The DoR in participants assessed by the investigator is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. The DoR was analyzed for those participants who achieved OR.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O8">
            <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O9">
            <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O10">
            <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O11">
            <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O12">
            <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O13">
            <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O14">
            <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O15">
            <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O16">
            <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>DoR Assessed by Investigator in the Dose-expansion Phase</title>
          <description>The DoR in participants assessed by the investigator is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
          <population>As-treated population included all participants who received any dose of study drug. The DoR was analyzed for those participants who achieved OR.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="7"/>
                <count group_id="O2" value="3"/>
                <count group_id="O3" value="54"/>
                <count group_id="O4" value="4"/>
                <count group_id="O5" value="3"/>
                <count group_id="O6" value="1"/>
                <count group_id="O7" value="2"/>
                <count group_id="O8" value="1"/>
                <count group_id="O9" value="1"/>
                <count group_id="O10" value="42"/>
                <count group_id="O11" value="0"/>
                <count group_id="O12" value="3"/>
                <count group_id="O13" value="2"/>
                <count group_id="O14" value="2"/>
                <count group_id="O15" value="15"/>
                <count group_id="O16" value="3"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="19.71" lower_limit="1.9" upper_limit="44.0"/>
                    <measurement group_id="O2" value="14.75" lower_limit="12.8" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O3" value="9.95" lower_limit="8.3" upper_limit="16.4"/>
                    <measurement group_id="O4" value="16.20" lower_limit="7.2" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O5" value="NA" lower_limit="7.9" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O6" value="9.23" lower_limit="NA" upper_limit="NA">95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O7" value="NA" lower_limit="NA" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O8" value="NA" lower_limit="NA" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O9" value="5.36" lower_limit="NA" upper_limit="NA">95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O10" value="NA" lower_limit="14.6" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O12" value="24.87" lower_limit="4.8" upper_limit="24.9"/>
                    <measurement group_id="O13" value="7.92" lower_limit="6.1" upper_limit="9.7"/>
                    <measurement group_id="O14" value="23.51" lower_limit="14.6" upper_limit="32.4"/>
                    <measurement group_id="O15" value="26.91" lower_limit="12.7" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O16" value="8.64" lower_limit="4.4" upper_limit="16.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Disease Control Rate (DCR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</title>
        <description>Percentage of participants with disease control assessed by BICR in NSCLC and SCCHN cohorts is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants in FAS population with NSCLC and SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with SCCHN received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with NSCLC received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Disease Control Rate (DCR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase</title>
          <description>Percentage of participants with disease control assessed by BICR in NSCLC and SCCHN cohorts is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
          <population>Participants in FAS population with NSCLC and SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="55"/>
                <count group_id="O2" value="275"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="25.5" lower_limit="14.7" upper_limit="39.0"/>
                    <measurement group_id="O2" value="44.4" lower_limit="38.4" upper_limit="50.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>DCR Assessed by Investigator in the Dose-expansion Phase</title>
        <description>Percentage of participants with disease control assessed by the investigator is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O8">
            <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O9">
            <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O10">
            <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O11">
            <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O12">
            <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O13">
            <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O14">
            <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O15">
            <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O16">
            <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>DCR Assessed by Investigator in the Dose-expansion Phase</title>
          <description>Percentage of participants with disease control assessed by the investigator is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
          <population>As-treated population included all participants who received any dose of study drug.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="62"/>
                <count group_id="O2" value="22"/>
                <count group_id="O3" value="302"/>
                <count group_id="O4" value="40"/>
                <count group_id="O5" value="21"/>
                <count group_id="O6" value="24"/>
                <count group_id="O7" value="51"/>
                <count group_id="O8" value="40"/>
                <count group_id="O9" value="31"/>
                <count group_id="O10" value="201"/>
                <count group_id="O11" value="20"/>
                <count group_id="O12" value="47"/>
                <count group_id="O13" value="20"/>
                <count group_id="O14" value="21"/>
                <count group_id="O15" value="62"/>
                <count group_id="O16" value="10"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="33.9" lower_limit="22.3" upper_limit="47.0"/>
                    <measurement group_id="O2" value="45.5" lower_limit="25.7" upper_limit="70.2"/>
                    <measurement group_id="O3" value="51.7" lower_limit="45.9" upper_limit="57.4"/>
                    <measurement group_id="O4" value="65.0" lower_limit="48.3" upper_limit="79.4"/>
                    <measurement group_id="O5" value="57.1" lower_limit="34.0" upper_limit="78.2"/>
                    <measurement group_id="O6" value="37.5" lower_limit="18.8" upper_limit="59.4"/>
                    <measurement group_id="O7" value="37.3" lower_limit="24.1" upper_limit="51.9"/>
                    <measurement group_id="O8" value="22.5" lower_limit="10.8" upper_limit="38.5"/>
                    <measurement group_id="O9" value="22.6" lower_limit="9.6" upper_limit="41.1"/>
                    <measurement group_id="O10" value="43.3" lower_limit="36.3" upper_limit="50.4"/>
                    <measurement group_id="O11" value="0" lower_limit="NA" upper_limit="NA">95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O12" value="44.7" lower_limit="30.2" upper_limit="59.9"/>
                    <measurement group_id="O13" value="50.0" lower_limit="27.2" upper_limit="72.8"/>
                    <measurement group_id="O14" value="28.6" lower_limit="11.3" upper_limit="52.2"/>
                    <measurement group_id="O15" value="67.7" lower_limit="54.7" upper_limit="79.1"/>
                    <measurement group_id="O16" value="50.0" lower_limit="18.7" upper_limit="81.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Progression-free Survival (PFS) Assessed by BICR in NSCLC Cohort in the Dose-expansion Phase</title>
        <description>The PFS assessed by BICR in NSCLC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants in As-treated population with NSCLC were analyzed. As-treated population included all participants who received any dose of study drug.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with NSCLC received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Progression-free Survival (PFS) Assessed by BICR in NSCLC Cohort in the Dose-expansion Phase</title>
          <description>The PFS assessed by BICR in NSCLC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
          <population>Participants in As-treated population with NSCLC were analyzed. As-treated population included all participants who received any dose of study drug.</population>
          <units>Percentage of participants</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="304"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.1" lower_limit="1.5" upper_limit="2.6"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>PFS Assessed by BICR in SCCHN Cohort in the Dose-expansion Phase</title>
        <description>The PFS assessed by BICR in SCCHN cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>Participants in FAS population with SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with SCCHN received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>PFS Assessed by BICR in SCCHN Cohort in the Dose-expansion Phase</title>
          <description>The PFS assessed by BICR in SCCHN cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
          <population>Participants in FAS population with SCCHN were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="62"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" lower_limit="1.3" upper_limit="1.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>PFS Assessed by Investigator in the Dose-expansion Phase</title>
        <description>The PFS assessed by the investigator is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O8">
            <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O9">
            <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O10">
            <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O11">
            <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O12">
            <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O13">
            <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O14">
            <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O15">
            <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O16">
            <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>PFS Assessed by Investigator in the Dose-expansion Phase</title>
          <description>The PFS assessed by the investigator is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
          <population>As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="62"/>
                <count group_id="O2" value="22"/>
                <count group_id="O3" value="302"/>
                <count group_id="O4" value="40"/>
                <count group_id="O5" value="21"/>
                <count group_id="O6" value="24"/>
                <count group_id="O7" value="51"/>
                <count group_id="O8" value="40"/>
                <count group_id="O9" value="31"/>
                <count group_id="O10" value="201"/>
                <count group_id="O11" value="20"/>
                <count group_id="O12" value="47"/>
                <count group_id="O13" value="20"/>
                <count group_id="O14" value="21"/>
                <count group_id="O15" value="62"/>
                <count group_id="O16" value="10"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" lower_limit="1.4" upper_limit="1.6"/>
                    <measurement group_id="O2" value="1.5" lower_limit="1.2" upper_limit="5.6"/>
                    <measurement group_id="O3" value="2.6" lower_limit="1.9" upper_limit="3.2"/>
                    <measurement group_id="O4" value="2.7" lower_limit="1.4" upper_limit="5.3"/>
                    <measurement group_id="O5" value="2.8" lower_limit="1.2" upper_limit="9.1"/>
                    <measurement group_id="O6" value="1.4" lower_limit="1.3" upper_limit="4.6"/>
                    <measurement group_id="O7" value="1.4" lower_limit="1.2" upper_limit="2.4"/>
                    <measurement group_id="O8" value="1.3" lower_limit="1.2" upper_limit="1.6"/>
                    <measurement group_id="O9" value="1.5" lower_limit="1.3" upper_limit="1.7"/>
                    <measurement group_id="O10" value="1.8" lower_limit="1.4" upper_limit="2.6"/>
                    <measurement group_id="O11" value="1.4" lower_limit="1.2" upper_limit="2.3"/>
                    <measurement group_id="O12" value="1.8" lower_limit="1.4" upper_limit="2.7"/>
                    <measurement group_id="O13" value="2.6" lower_limit="1.4" upper_limit="3.0"/>
                    <measurement group_id="O14" value="1.5" lower_limit="0.9" upper_limit="1.8"/>
                    <measurement group_id="O15" value="5.4" lower_limit="2.9" upper_limit="11.1"/>
                    <measurement group_id="O16" value="2.2" lower_limit="0.7" upper_limit="5.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>OS in the Dose-Expansion Phase</title>
        <description>OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>As-treated population included all participants who received any dose of study drug. The &quot;Number of Participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O4">
            <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O5">
            <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O6">
            <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O7">
            <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O8">
            <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O9">
            <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O10">
            <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O11">
            <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O12">
            <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O13">
            <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O14">
            <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O15">
            <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O16">
            <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
            <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>OS in the Dose-Expansion Phase</title>
          <description>OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
          <population>As-treated population included all participants who received any dose of study drug. The &quot;Number of Participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="62"/>
                <count group_id="O2" value="22"/>
                <count group_id="O3" value="304"/>
                <count group_id="O4" value="40"/>
                <count group_id="O5" value="21"/>
                <count group_id="O6" value="24"/>
                <count group_id="O7" value="51"/>
                <count group_id="O8" value="40"/>
                <count group_id="O9" value="31"/>
                <count group_id="O10" value="201"/>
                <count group_id="O11" value="20"/>
                <count group_id="O12" value="47"/>
                <count group_id="O13" value="20"/>
                <count group_id="O14" value="21"/>
                <count group_id="O15" value="62"/>
                <count group_id="O16" value="10"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="8.4" lower_limit="5.7" upper_limit="12.3"/>
                    <measurement group_id="O2" value="11.6" lower_limit="3.0" upper_limit="22.8"/>
                    <measurement group_id="O3" value="12.4" lower_limit="9.3" upper_limit="15.2"/>
                    <measurement group_id="O4" value="13.2" lower_limit="6.3" upper_limit="23.0"/>
                    <measurement group_id="O5" value="NA" lower_limit="15.1" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O6" value="8.4" lower_limit="4.5" upper_limit="14.3"/>
                    <measurement group_id="O7" value="4.9" lower_limit="2.6" upper_limit="9.1"/>
                    <measurement group_id="O8" value="5.5" lower_limit="3.5" upper_limit="16.8"/>
                    <measurement group_id="O9" value="5.7" lower_limit="4.8" upper_limit="8.0"/>
                    <measurement group_id="O10" value="10.5" lower_limit="6.9" upper_limit="15.7"/>
                    <measurement group_id="O11" value="10.0" lower_limit="6.2" upper_limit="13.0"/>
                    <measurement group_id="O12" value="11.1" lower_limit="8.2" upper_limit="16.6"/>
                    <measurement group_id="O13" value="15.8" lower_limit="8.1" upper_limit="23.3"/>
                    <measurement group_id="O14" value="4.8" lower_limit="1.3" upper_limit="10.4"/>
                    <measurement group_id="O15" value="24.1" lower_limit="12.4" upper_limit="37.1"/>
                    <measurement group_id="O16" value="16.1" lower_limit="0.9" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>ORR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The ORR assessed by BICR in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the FAS population were analyzed. FAS population included all participnats who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>ORR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The ORR assessed by BICR in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the FAS population were analyzed. FAS population included all participnats who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="85"/>
                <count group_id="O2" value="199"/>
                <count group_id="O3" value="101"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="5.9" lower_limit="1.9" upper_limit="13.2"/>
                    <measurement group_id="O2" value="17.6" lower_limit="12.6" upper_limit="23.6"/>
                    <measurement group_id="O3" value="27.7" lower_limit="19.3" upper_limit="37.5"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>ORR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The ORR assessed by the investigator in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>ORR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The ORR assessed by the investigator in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as &gt;= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="86"/>
                <count group_id="O2" value="201"/>
                <count group_id="O3" value="102"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="7.0" lower_limit="2.6" upper_limit="14.6"/>
                    <measurement group_id="O2" value="20.9" lower_limit="15.5" upper_limit="27.2"/>
                    <measurement group_id="O3" value="33.3" lower_limit="24.3" upper_limit="43.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>DoR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The DoR assessed by BICR in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in FAS population (all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 wks by 16Oct2017) were analyzed. DoR was analyzed for those participants who achieved OR.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>DoR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The DoR assessed by BICR in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in FAS population (all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 wks by 16Oct2017) were analyzed. DoR was analyzed for those participants who achieved OR.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="5"/>
                <count group_id="O2" value="35"/>
                <count group_id="O3" value="28"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="12.25" lower_limit="8.6" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O2" value="NA" lower_limit="16.0" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O3" value="NA" lower_limit="16.0" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>DoR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The DoR assessed by investigator in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The DoR was analyzed for those participants who achieved OR.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>DoR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The DoR assessed by investigator in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The DoR was analyzed for those participants who achieved OR.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="6"/>
                <count group_id="O2" value="42"/>
                <count group_id="O3" value="34"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="14.82" lower_limit="6.9" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O2" value="19.71" lower_limit="14.6" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O3" value="NA" lower_limit="12.3" upper_limit="NA">Median and Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>DCR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>Percentage of participants with disease control assessed by BICR in UC cohort is reported. The DCR is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the FAS population were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>DCR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>Percentage of participants with disease control assessed by BICR in UC cohort is reported. The DCR is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the FAS population were analyzed. FAS population included all participants who received any dose of study drug, had measurable disease at baseline (Day 1) per BICR and were followed for at least 24 weeks by 16Oct2017.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="85"/>
                <count group_id="O2" value="199"/>
                <count group_id="O3" value="101"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="21.2" lower_limit="13.1" upper_limit="31.4"/>
                    <measurement group_id="O2" value="35.2" lower_limit="28.6" upper_limit="42.2"/>
                    <measurement group_id="O3" value="43.6" lower_limit="33.7" upper_limit="53.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>DCR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>Percentage of participants with disease control assessed by investigator in UC cohort is reported. Disease control is defined as a best overall response of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR not sufficient increase to qualify for disease progression.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>DCR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>Percentage of participants with disease control assessed by investigator in UC cohort is reported. Disease control is defined as a best overall response of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (&gt;= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR not sufficient increase to qualify for disease progression.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug.</population>
          <units>Percentage of participants</units>
          <param>Number</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="86"/>
                <count group_id="O2" value="201"/>
                <count group_id="O3" value="102"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="30.2" lower_limit="20.8" upper_limit="41.1"/>
                    <measurement group_id="O2" value="43.3" lower_limit="36.3" upper_limit="50.4"/>
                    <measurement group_id="O3" value="53.9" lower_limit="43.8" upper_limit="63.8"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>PFS Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The PFS assessed by BICR in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>PFS Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The PFS assessed by BICR in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="86"/>
                <count group_id="O2" value="201"/>
                <count group_id="O3" value="102"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" lower_limit="1.3" upper_limit="1.5"/>
                    <measurement group_id="O2" value="1.5" lower_limit="1.4" upper_limit="1.8"/>
                    <measurement group_id="O3" value="1.9" lower_limit="1.4" upper_limit="2.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>PFS Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The PFS assessed by the investigator in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>PFS Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The PFS assessed by the investigator in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="86"/>
                <count group_id="O2" value="201"/>
                <count group_id="O3" value="102"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="1.4" lower_limit="1.4" upper_limit="1.7"/>
                    <measurement group_id="O2" value="1.8" lower_limit="1.4" upper_limit="2.6"/>
                    <measurement group_id="O3" value="2.8" lower_limit="1.8" upper_limit="3.7"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>OS in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
        <description>The OS in UC cohort is reported. The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of Participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC Total Cohort</title>
            <description>Participants with UC (Total PD-L1 status - high, low/Negative, and unknown) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O3">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>OS in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase</title>
          <description>The OS in UC cohort is reported. The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status as low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining), total (PD-L1 high, PD-L1 low/negative, and PD-L1 unknown), and high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of Participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="86"/>
                <count group_id="O2" value="201"/>
                <count group_id="O3" value="102"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="4.8" lower_limit="3.3" upper_limit="8.1"/>
                    <measurement group_id="O2" value="10.5" lower_limit="6.9" upper_limit="15.7"/>
                    <measurement group_id="O3" value="19.8" lower_limit="9.3" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Adjusted Comparison of PFS by PD-L1 Status in UC Cohort in the Dose-expansion Phase</title>
        <description>The PFS by PD-L1 status in UC cohort is reported. The PFS estimates are adjusted for baseline eastern cooperative oncology (ECOG), smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) and low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Adjusted Comparison of PFS by PD-L1 Status in UC Cohort in the Dose-expansion Phase</title>
          <description>The PFS by PD-L1 status in UC cohort is reported. The PFS estimates are adjusted for baseline eastern cooperative oncology (ECOG), smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status as high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) and low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="61"/>
                <count group_id="O2" value="39"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="2.6" lower_limit="1.4" upper_limit="3.9"/>
                    <measurement group_id="O2" value="1.5" lower_limit="1.4" upper_limit="2.4"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <non_inferiority_type>Equivalence</non_inferiority_type>
            <non_inferiority_desc>Other</non_inferiority_desc>
            <p_value>0.016</p_value>
            <method>Regression, Cox</method>
          </analysis>
        </analysis_list>
      </outcome>
      <outcome>
        <type>Secondary</type>
        <title>Adjusted Comparison of OS by PD-L1 Status in UC Cohort in the Dose-expansion Phase</title>
        <description>The OS by PD-L1 status in UC cohort is reported. The OS estimates are adjusted for baseline ECOG, smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
        <time_frame>From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)</time_frame>
        <population>The UC cohort participants with PD-L1 status as high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) and low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of Participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
        <group_list>
          <group group_id="O1">
            <title>Expansion UC PD-L1 High Cohort</title>
            <description>Participants with UC (PD-L1 status high) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
          <group group_id="O2">
            <title>Expansion UC PD-L1 Low/Negative Cohort</title>
            <description>Participants with UC (PD-L1 status low/Negative) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
          </group>
        </group_list>
        <measure>
          <title>Adjusted Comparison of OS by PD-L1 Status in UC Cohort in the Dose-expansion Phase</title>
          <description>The OS by PD-L1 status in UC cohort is reported. The OS estimates are adjusted for baseline ECOG, smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.</description>
          <population>The UC cohort participants with PD-L1 status as high (&gt;= 25% tumor cell membrane or &gt;=25% immune cell staining) and low/negative (&lt;25% tumor cell membrane and &lt;25% immune cell staining) included in the As-treated population were analyzed. As-treated population included all participants who received any dose of study drug. The &quot;Number of Participants Analyzed&quot; denotes the number of participants evaluated for this outcome measure.</population>
          <units>Months</units>
          <param>Median</param>
          <dispersion>95% Confidence Interval</dispersion>
          <analyzed_list>
            <analyzed>
              <units>Participants</units>
              <scope>Measure</scope>
              <count_list>
                <count group_id="O1" value="61"/>
                <count group_id="O2" value="39"/>
              </count_list>
            </analyzed>
          </analyzed_list>
          <class_list>
            <class>
              <category_list>
                <category>
                  <measurement_list>
                    <measurement group_id="O1" value="18.4" lower_limit="7.8" upper_limit="NA">Upper limit of 95% CI could not be derived due to insufficient events being observed at the time of the analysis.</measurement>
                    <measurement group_id="O2" value="3.4" lower_limit="2.4" upper_limit="14.3"/>
                  </measurement_list>
                </category>
              </category_list>
            </class>
          </class_list>
        </measure>
        <analysis_list>
          <analysis>
            <group_id_list>
              <group_id>O1</group_id>
              <group_id>O2</group_id>
            </group_id_list>
            <non_inferiority_type>Equivalence</non_inferiority_type>
            <non_inferiority_desc>Other</non_inferiority_desc>
            <p_value>0.0046</p_value>
            <method>Regression, Cox</method>
          </analysis>
        </analysis_list>
      </outcome>
    </outcome_list>

    <reported_events>
      <time_frame>From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)</time_frame>
      <group_list>
        <group group_id="E1">
          <title>Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)</title>
          <description>Participants received intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E2">
          <title>Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E3">
          <title>Escalation Cohort (MEDI4736 1 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E4">
          <title>Escalation Cohort (MEDI4736 3 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E5">
          <title>Escalation Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E6">
          <title>Escalation Cohort (MEDI4736 15 mg/kg Q3W)</title>
          <description>Participants received IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E7">
          <title>Exploration Durvalumab 20 mg/kg (Q4W)</title>
          <description>Participants received IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E8">
          <title>Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with squamous cell carcinoma of the head and neck (SCCHN) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E9">
          <title>Expansion Non-SCCHN HPV Positive Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E10">
          <title>Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with non-small-cell lung cancer (NSCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E11">
          <title>Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with hepatocellular carcinoma (HCC Total) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E12">
          <title>Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with advance cutaneous melanoma (ACM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E13">
          <title>Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with uveal melanoma (UM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E14">
          <title>Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with gastroesophageal cancer (GEC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E15">
          <title>Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with triple-negative breast cancer (TNBC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E16">
          <title>Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with pancreatic adenocarcinoma (PAC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E17">
          <title>Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with urothelial carcinoma (UC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E18">
          <title>Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with glioblastoma multiforme (GBM) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E19">
          <title>Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with ovarian cancer (OC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E20">
          <title>Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with soft- tissue sarcoma (STS) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E21">
          <title>Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with small-cell lung cancer (SCLC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E22">
          <title>Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with microsatellite instability (MSI)-high cancer received IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
        <group group_id="E23">
          <title>Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)</title>
          <description>Participants with nasopharyngeal carcinoma (NPC) received IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurred first.</description>
        </group>
      </group_list>
      <serious_events>
        <default_vocab>MedDRA 22.1</default_vocab>
        <default_assessment>Systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, all-cause mortality</sub_title>
                <counts group_id="E1" subjects_affected="4" subjects_at_risk="4"/>
                <counts group_id="E2" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E3" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" subjects_affected="3" subjects_at_risk="3"/>
                <counts group_id="E5" subjects_affected="6" subjects_at_risk="6"/>
                <counts group_id="E6" subjects_affected="4" subjects_at_risk="7"/>
                <counts group_id="E7" subjects_affected="17" subjects_at_risk="21"/>
                <counts group_id="E8" subjects_affected="42" subjects_at_risk="62"/>
                <counts group_id="E9" subjects_affected="17" subjects_at_risk="22"/>
                <counts group_id="E10" subjects_affected="208" subjects_at_risk="304"/>
                <counts group_id="E11" subjects_affected="30" subjects_at_risk="40"/>
                <counts group_id="E12" subjects_affected="8" subjects_at_risk="21"/>
                <counts group_id="E13" subjects_affected="19" subjects_at_risk="24"/>
                <counts group_id="E14" subjects_affected="42" subjects_at_risk="51"/>
                <counts group_id="E15" subjects_affected="23" subjects_at_risk="40"/>
                <counts group_id="E16" subjects_affected="23" subjects_at_risk="31"/>
                <counts group_id="E17" subjects_affected="128" subjects_at_risk="201"/>
                <counts group_id="E18" subjects_affected="16" subjects_at_risk="20"/>
                <counts group_id="E19" subjects_affected="36" subjects_at_risk="47"/>
                <counts group_id="E20" subjects_affected="16" subjects_at_risk="20"/>
                <counts group_id="E21" subjects_affected="17" subjects_at_risk="21"/>
                <counts group_id="E22" subjects_affected="35" subjects_at_risk="62"/>
                <counts group_id="E23" subjects_affected="7" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Total, serious adverse events</sub_title>
                <counts group_id="E1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E3" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" subjects_affected="3" subjects_at_risk="6"/>
                <counts group_id="E6" subjects_affected="3" subjects_at_risk="7"/>
                <counts group_id="E7" subjects_affected="13" subjects_at_risk="21"/>
                <counts group_id="E8" subjects_affected="30" subjects_at_risk="62"/>
                <counts group_id="E9" subjects_affected="16" subjects_at_risk="22"/>
                <counts group_id="E10" subjects_affected="163" subjects_at_risk="304"/>
                <counts group_id="E11" subjects_affected="24" subjects_at_risk="40"/>
                <counts group_id="E12" subjects_affected="7" subjects_at_risk="21"/>
                <counts group_id="E13" subjects_affected="12" subjects_at_risk="24"/>
                <counts group_id="E14" subjects_affected="26" subjects_at_risk="51"/>
                <counts group_id="E15" subjects_affected="20" subjects_at_risk="40"/>
                <counts group_id="E16" subjects_affected="25" subjects_at_risk="31"/>
                <counts group_id="E17" subjects_affected="117" subjects_at_risk="201"/>
                <counts group_id="E18" subjects_affected="9" subjects_at_risk="20"/>
                <counts group_id="E19" subjects_affected="26" subjects_at_risk="47"/>
                <counts group_id="E20" subjects_affected="7" subjects_at_risk="20"/>
                <counts group_id="E21" subjects_affected="14" subjects_at_risk="21"/>
                <counts group_id="E22" subjects_affected="31" subjects_at_risk="62"/>
                <counts group_id="E23" subjects_affected="7" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Blood and lymphatic system disorders</title>
            <event_list>
              <event>
                <sub_title>Anaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Disseminated intravascular coagulation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Immune thrombocytopenic purpura</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="3" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Leukocytosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lymph node pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Neutropenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Thrombocytopenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Thrombocytosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Cardiac disorders</title>
            <event_list>
              <event>
                <sub_title>Acute coronary syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Angina pectoris</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Atrial fibrillation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Atrial flutter</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Atrioventricular block first degree</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cardiac arrest</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cardiac failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cardiac failure congestive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cardiac tamponade</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cardio-respiratory arrest</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cardiovascular disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ischaemic cardiomyopathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Myocardial infarction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Myocarditis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Palpitations</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pericardial effusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Sinus tachycardia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Supraventricular tachycardia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Trifascicular block</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ventricular tachycardia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Endocrine disorders</title>
            <event_list>
              <event>
                <sub_title>Adrenal insufficiency</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperthyroidism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Steroid withdrawal syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Gastrointestinal disorders</title>
            <event_list>
              <event>
                <sub_title>Abdominal pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal pain lower</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal pain upper</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ascites</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Colitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Colitis ischaemic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Colonic fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Constipation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Diarrhoea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Duodenal obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Duodenal stenosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysphagia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Enterovesical fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Faecaloma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gastric perforation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gastrointestinal haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Haematemesis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ileus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Intestinal ischaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Intestinal obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Intestinal perforation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Intra-abdominal haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Large intestinal obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lower gastrointestinal haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nausea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pancreatitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Proctalgia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Proctitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Retroperitoneal haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Small intestinal obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Small intestinal perforation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Subileus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Upper gastrointestinal haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Varices oesophageal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vomiting</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>General disorders</title>
            <event_list>
              <event>
                <sub_title>Asthenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Chest pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Chills</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Complication associated with device</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Death</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Fatigue</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>General physical health deterioration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="5" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="11" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="5" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Malaise</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Multiple organ dysfunction syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Non-cardiac chest pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oedema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oedema peripheral</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pyrexia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Hepatobiliary disorders</title>
            <event_list>
              <event>
                <sub_title>Autoimmune hepatitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cholangitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cholecystitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cholelithiasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Chronic hepatic failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatic failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatic function abnormal</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatic haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatic vein thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatobiliary disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatocellular injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperbilirubinaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Liver injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Abdominal abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bacteraemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bartholinitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bronchitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cellulitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Clostridium difficile colitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Clostridium difficile infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Device related infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Diverticulitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Erysipelas</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Herpes zoster</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Infected fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Kidney infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Necrotising fasciitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Osteomyelitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peritonitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peritonitis bacterial</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumonia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="29" subjects_affected="21" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Postoperative wound infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pulmonary tuberculosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pyelonephritis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Respiratory tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Sepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Septic shock</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Sinusitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Stoma site infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Subcutaneous abscess</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Upper respiratory tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary tract candidiasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="13" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urosepsis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Injury, poisoning and procedural complications</title>
            <event_list>
              <event>
                <sub_title>Contusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Fall</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Femoral neck fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Femur fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hip fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Infusion related reaction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Post procedural complication</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Spinal compression fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Spinal fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Toxicity to various agents</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Investigations</title>
            <event_list>
              <event>
                <sub_title>Alanine aminotransferase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Aspartate aminotransferase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood alkaline phosphatase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood bilirubin increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood creatinine increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood electrolytes decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Eastern cooperative oncology group performance status worsened</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gamma-glutamyltransferase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>International normalised ratio increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transaminases increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Metabolism and nutrition disorders</title>
            <event_list>
              <event>
                <sub_title>Decreased appetite</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dehydration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Failure to thrive</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypercalcaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperglycaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperkalaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperlipasaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypokalaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypomagnesaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyponatraemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypophagia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lactic acidosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Metabolic acidosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tumour lysis syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Arthralgia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Back pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bone pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Flank pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Groin pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Muscular weakness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Musculoskeletal chest pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Musculoskeletal pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Myositis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Neck pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pain in extremity</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pathological fracture</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Polymyalgia rheumatica</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Neoplasms benign, malignant and unspecified (incl cysts and polyps)</title>
            <event_list>
              <event>
                <sub_title>Adenocarcinoma of the cervix</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Adenocarcinoma pancreas</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Anal cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bladder cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="50" subjects_affected="45" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bladder cancer stage iv</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bladder transitional cell carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Breast cancer metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cancer pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cervix carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Choroid melanoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Colon cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Colorectal adenocarcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Colorectal cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="6" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Endometrial cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gastric cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="4" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gastrooesophageal cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Glioblastoma multiforme</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatocellular carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="8" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Intraocular melanoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lung adenocarcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lung cancer metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lung neoplasm</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lung neoplasm malignant</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="14" subjects_affected="13" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Malignant melanoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Malignant neoplasm of renal pelvis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Malignant pleural effusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Metastases to bladder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Metastatic carcinoma of the bladder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Metastatic gastric cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Metastatic malignant melanoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nasopharyngeal cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="5" subjects_affected="4" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Neoplasm swelling</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Non-small cell lung cancer</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="55" subjects_affected="47" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Non-small cell lung cancer metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oesophageal adenocarcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oesophageal cancer metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oesophageal carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oncologic complication</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ovarian cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="7" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pancreatic carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="9" subjects_affected="8" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pancreatic carcinoma metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pancreatic carcinoma stage iv</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Paraneoplastic syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Prostate cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Small cell lung cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="13" subjects_affected="8" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Soft tissue sarcoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Squamous cell carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Squamous cell carcinoma of head and neck</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="6" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Squamous cell carcinoma of lung</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Squamous cell carcinoma of pharynx</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Squamous cell carcinoma of the hypopharynx</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transitional cell cancer of the renal pelvis and ureter</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transitional cell carcinoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="8" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transitional cell carcinoma metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transitional cell carcinoma recurrent</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Triple negative breast cancer</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tumour associated fever</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tumour flare</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tumour pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vulval cancer metastatic</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Nervous system disorders</title>
            <event_list>
              <event>
                <sub_title>Aphasia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ataxia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Basal ganglia infarction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cauda equina syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cerebrovascular accident</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cognitive disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dizziness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysarthria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Facial paralysis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Headache</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hemianopia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hemianopia homonymous</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hemiparesis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hydrocephalus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ischaemic neuropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ischaemic stroke</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Migraine</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Monoparesis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nerve compression</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nervous system disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Paraesthesia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Partial seizures</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peripheral motor neuropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peripheral sensory neuropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Seizure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Spinal cord compression</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Spinal cord oedema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Syncope</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transient ischaemic attack</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Trigeminal neuralgia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Product Issues</title>
            <event_list>
              <event>
                <sub_title>Device dislocation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Device malfunction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Device occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Psychiatric disorders</title>
            <event_list>
              <event>
                <sub_title>Anxiety</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Confusional state</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Mental status changes</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Suicide attempt</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Renal and urinary disorders</title>
            <event_list>
              <event>
                <sub_title>Acute kidney injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="9" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Azotaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Haematuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hydronephrosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hydroureter</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Proteinuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ureteric obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary bladder polyp</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary tract obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary tract pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Reproductive system and breast disorders</title>
            <event_list>
              <event>
                <sub_title>Female genital tract fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vaginal discharge</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Respiratory, thoracic and mediastinal disorders</title>
            <event_list>
              <event>
                <sub_title>Acute respiratory failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Bronchial obstruction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Chronic obstructive pulmonary disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cough</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dyspnoea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="24" subjects_affected="23" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="6" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dyspnoea exertional</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Haemoptysis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypoxia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Obstructive airways disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oesophagobronchial fistula</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pharyngeal haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pleural effusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="9" subjects_affected="9" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pleuritic pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumonia aspiration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumonitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumothorax</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pulmonary embolism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pulmonary haemorrhage</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pulmonary venous thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Respiratory distress</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Respiratory failure</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="9" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tracheal stenosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Skin and subcutaneous tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Erythema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Vascular disorders</title>
            <event_list>
              <event>
                <sub_title>Embolism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Haematoma</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypertension</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypotension</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Superior vena cava syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vascular occlusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vena cava thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Venous thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </serious_events>
      <other_events>
        <frequency_threshold>5</frequency_threshold>
        <default_vocab>MedDRA 22.1</default_vocab>
        <default_assessment>Systematic Assessment</default_assessment>
        <category_list>
          <category>
            <title>Total</title>
            <event_list>
              <event>
                <sub_title>Total, other adverse events</sub_title>
                <counts group_id="E1" subjects_affected="3" subjects_at_risk="4"/>
                <counts group_id="E2" subjects_affected="4" subjects_at_risk="4"/>
                <counts group_id="E3" subjects_affected="3" subjects_at_risk="3"/>
                <counts group_id="E4" subjects_affected="3" subjects_at_risk="3"/>
                <counts group_id="E5" subjects_affected="6" subjects_at_risk="6"/>
                <counts group_id="E6" subjects_affected="7" subjects_at_risk="7"/>
                <counts group_id="E7" subjects_affected="20" subjects_at_risk="21"/>
                <counts group_id="E8" subjects_affected="61" subjects_at_risk="62"/>
                <counts group_id="E9" subjects_affected="22" subjects_at_risk="22"/>
                <counts group_id="E10" subjects_affected="292" subjects_at_risk="304"/>
                <counts group_id="E11" subjects_affected="40" subjects_at_risk="40"/>
                <counts group_id="E12" subjects_affected="19" subjects_at_risk="21"/>
                <counts group_id="E13" subjects_affected="22" subjects_at_risk="24"/>
                <counts group_id="E14" subjects_affected="50" subjects_at_risk="51"/>
                <counts group_id="E15" subjects_affected="39" subjects_at_risk="40"/>
                <counts group_id="E16" subjects_affected="31" subjects_at_risk="31"/>
                <counts group_id="E17" subjects_affected="194" subjects_at_risk="201"/>
                <counts group_id="E18" subjects_affected="18" subjects_at_risk="20"/>
                <counts group_id="E19" subjects_affected="46" subjects_at_risk="47"/>
                <counts group_id="E20" subjects_affected="20" subjects_at_risk="20"/>
                <counts group_id="E21" subjects_affected="17" subjects_at_risk="21"/>
                <counts group_id="E22" subjects_affected="57" subjects_at_risk="62"/>
                <counts group_id="E23" subjects_affected="10" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Blood and lymphatic system disorders</title>
            <event_list>
              <event>
                <sub_title>Anaemia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="11" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E9" events="7" subjects_affected="5" subjects_at_risk="22"/>
                <counts group_id="E10" events="74" subjects_affected="47" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E12" events="12" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="20" subjects_affected="7" subjects_at_risk="51"/>
                <counts group_id="E15" events="7" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="7" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="72" subjects_affected="43" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="12" subjects_affected="10" subjects_at_risk="47"/>
                <counts group_id="E20" events="14" subjects_affected="8" subjects_at_risk="20"/>
                <counts group_id="E21" events="5" subjects_affected="5" subjects_at_risk="21"/>
                <counts group_id="E22" events="22" subjects_affected="11" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Leukopenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Neutropenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Splenomegaly</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Thrombocytopenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="12" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="7" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="9" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Cardiac disorders</title>
            <event_list>
              <event>
                <sub_title>Atrial fibrillation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Extrasystoles</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Palpitations</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Ear and labyrinth disorders</title>
            <event_list>
              <event>
                <sub_title>Ear pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Eustachian tube dysfunction</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Otorrhoea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Endocrine disorders</title>
            <event_list>
              <event>
                <sub_title>Hyperthyroidism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="19" subjects_affected="12" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypothyroidism</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="34" subjects_affected="29" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="6" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="21" subjects_affected="17" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="6" subjects_affected="6" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Eye disorders</title>
            <event_list>
              <event>
                <sub_title>Cataract</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Conjunctival hyperaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Diplopia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Eye pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vision blurred</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vitreous floaters</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Gastrointestinal disorders</title>
            <event_list>
              <event>
                <sub_title>Abdominal discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal distension</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="10" subjects_affected="9" subjects_at_risk="304"/>
                <counts group_id="E11" events="5" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="6" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="3" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="5" subjects_affected="4" subjects_at_risk="22"/>
                <counts group_id="E10" events="28" subjects_affected="23" subjects_at_risk="304"/>
                <counts group_id="E11" events="12" subjects_affected="11" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="27" subjects_affected="13" subjects_at_risk="51"/>
                <counts group_id="E15" events="4" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="12" subjects_affected="9" subjects_at_risk="31"/>
                <counts group_id="E17" events="25" subjects_affected="20" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="23" subjects_affected="15" subjects_at_risk="47"/>
                <counts group_id="E20" events="5" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="24" subjects_affected="12" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="3" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal pain lower</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Abdominal pain upper</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="4" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="11" subjects_affected="8" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="4" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ascites</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="5" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="11" subjects_affected="7" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Constipation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="2" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="3" subjects_affected="3" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="11" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E9" events="7" subjects_affected="6" subjects_at_risk="22"/>
                <counts group_id="E10" events="55" subjects_affected="48" subjects_at_risk="304"/>
                <counts group_id="E11" events="12" subjects_affected="11" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="20" subjects_affected="16" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E16" events="10" subjects_affected="9" subjects_at_risk="31"/>
                <counts group_id="E17" events="63" subjects_affected="55" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="16" subjects_affected="14" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="18" subjects_affected="13" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Diarrhoea</sub_title>
                <counts group_id="E1" events="2" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E2" events="3" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E3" events="4" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="18" subjects_affected="11" subjects_at_risk="62"/>
                <counts group_id="E9" events="9" subjects_affected="6" subjects_at_risk="22"/>
                <counts group_id="E10" events="96" subjects_affected="53" subjects_at_risk="304"/>
                <counts group_id="E11" events="12" subjects_affected="10" subjects_at_risk="40"/>
                <counts group_id="E12" events="8" subjects_affected="5" subjects_at_risk="21"/>
                <counts group_id="E13" events="10" subjects_affected="5" subjects_at_risk="24"/>
                <counts group_id="E14" events="19" subjects_affected="17" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E16" events="5" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="52" subjects_affected="36" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="17" subjects_affected="11" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="37" subjects_affected="18" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dry mouth</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="19" subjects_affected="17" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="7" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="4" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="14" subjects_affected="11" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dyspepsia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="11" subjects_affected="10" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="12" subjects_affected="12" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="5" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysphagia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="18" subjects_affected="15" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="12" subjects_affected="10" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Eructation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="9" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Flatulence</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="9" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="4" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gastrooesophageal reflux disease</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="13" subjects_affected="11" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="18" subjects_affected="7" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="5" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Impaired gastric emptying</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Loose tooth</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nausea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="6" subjects_affected="2" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="3" subjects_affected="3" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="15" subjects_affected="12" subjects_at_risk="62"/>
                <counts group_id="E9" events="8" subjects_affected="7" subjects_at_risk="22"/>
                <counts group_id="E10" events="82" subjects_affected="67" subjects_at_risk="304"/>
                <counts group_id="E11" events="16" subjects_affected="14" subjects_at_risk="40"/>
                <counts group_id="E12" events="8" subjects_affected="5" subjects_at_risk="21"/>
                <counts group_id="E13" events="14" subjects_affected="10" subjects_at_risk="24"/>
                <counts group_id="E14" events="26" subjects_affected="13" subjects_at_risk="51"/>
                <counts group_id="E15" events="9" subjects_affected="9" subjects_at_risk="40"/>
                <counts group_id="E16" events="15" subjects_affected="10" subjects_at_risk="31"/>
                <counts group_id="E17" events="70" subjects_affected="47" subjects_at_risk="201"/>
                <counts group_id="E18" events="6" subjects_affected="5" subjects_at_risk="20"/>
                <counts group_id="E19" events="25" subjects_affected="15" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="6" subjects_affected="6" subjects_at_risk="21"/>
                <counts group_id="E22" events="30" subjects_affected="18" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="3" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oral pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Stomatitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="5" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="7" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Toothache</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="12" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vomiting</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="3" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="13" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E9" events="10" subjects_affected="6" subjects_at_risk="22"/>
                <counts group_id="E10" events="53" subjects_affected="41" subjects_at_risk="304"/>
                <counts group_id="E11" events="16" subjects_affected="10" subjects_at_risk="40"/>
                <counts group_id="E12" events="5" subjects_affected="5" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="35" subjects_affected="10" subjects_at_risk="51"/>
                <counts group_id="E15" events="8" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E16" events="16" subjects_affected="8" subjects_at_risk="31"/>
                <counts group_id="E17" events="39" subjects_affected="27" subjects_at_risk="201"/>
                <counts group_id="E18" events="4" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="15" subjects_affected="10" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="5" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="15" subjects_affected="8" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="3" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>General disorders</title>
            <event_list>
              <event>
                <sub_title>Asthenia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="2" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="3" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="4" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="16" subjects_affected="14" subjects_at_risk="304"/>
                <counts group_id="E11" events="12" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="6" subjects_affected="5" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="44" subjects_affected="26" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="6" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="12" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Chest discomfort</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Chills</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="13" subjects_affected="13" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="4" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="7" subjects_affected="6" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Face oedema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Fatigue</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="3" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="7" subjects_affected="3" subjects_at_risk="6"/>
                <counts group_id="E6" events="5" subjects_affected="3" subjects_at_risk="7"/>
                <counts group_id="E7" events="13" subjects_affected="8" subjects_at_risk="21"/>
                <counts group_id="E8" events="29" subjects_affected="21" subjects_at_risk="62"/>
                <counts group_id="E9" events="13" subjects_affected="11" subjects_at_risk="22"/>
                <counts group_id="E10" events="165" subjects_affected="114" subjects_at_risk="304"/>
                <counts group_id="E11" events="23" subjects_affected="20" subjects_at_risk="40"/>
                <counts group_id="E12" events="10" subjects_affected="10" subjects_at_risk="21"/>
                <counts group_id="E13" events="12" subjects_affected="9" subjects_at_risk="24"/>
                <counts group_id="E14" events="73" subjects_affected="28" subjects_at_risk="51"/>
                <counts group_id="E15" events="11" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E16" events="24" subjects_affected="19" subjects_at_risk="31"/>
                <counts group_id="E17" events="91" subjects_affected="73" subjects_at_risk="201"/>
                <counts group_id="E18" events="8" subjects_affected="8" subjects_at_risk="20"/>
                <counts group_id="E19" events="23" subjects_affected="19" subjects_at_risk="47"/>
                <counts group_id="E20" events="11" subjects_affected="9" subjects_at_risk="20"/>
                <counts group_id="E21" events="7" subjects_affected="6" subjects_at_risk="21"/>
                <counts group_id="E22" events="19" subjects_affected="15" subjects_at_risk="62"/>
                <counts group_id="E23" events="4" subjects_affected="4" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gait disturbance</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>General physical health deterioration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hernia pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Influenza like illness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="7" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Mucosal inflammation</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="2" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="6" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Non-cardiac chest pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="18" subjects_affected="17" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="4" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oedema peripheral</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="5" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="4" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="42" subjects_affected="31" subjects_at_risk="304"/>
                <counts group_id="E11" events="17" subjects_affected="11" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="3" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="5" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="8" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="33" subjects_affected="28" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="12" subjects_affected="9" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="11" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="11" subjects_affected="9" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peripheral swelling</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pyrexia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="3" subjects_affected="3" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="17" subjects_affected="9" subjects_at_risk="62"/>
                <counts group_id="E9" events="6" subjects_affected="4" subjects_at_risk="22"/>
                <counts group_id="E10" events="45" subjects_affected="33" subjects_at_risk="304"/>
                <counts group_id="E11" events="18" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="5" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E13" events="3" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="14" subjects_affected="7" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E16" events="4" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="34" subjects_affected="28" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="8" subjects_at_risk="47"/>
                <counts group_id="E20" events="8" subjects_affected="5" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="22" subjects_affected="11" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Swelling face</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Thirst</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Hepatobiliary disorders</title>
            <event_list>
              <event>
                <sub_title>Hepatic pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hepatomegaly</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperbilirubinaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="5" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Jaundice</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ocular icterus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Immune system disorders</title>
            <event_list>
              <event>
                <sub_title>Food allergy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Infections and infestations</title>
            <event_list>
              <event>
                <sub_title>Bronchitis</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="12" subjects_affected="11" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Candida infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Escherichia urinary tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Eye infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gingivitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Herpes zoster</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Influenza</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nasopharyngitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="9" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="12" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Onychomycosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oral candidiasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="15" subjects_affected="13" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Otitis externa</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Otitis media</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumonia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="34" subjects_affected="25" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pyuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Rhinitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Sinusitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="14" subjects_affected="12" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Skin infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Upper respiratory tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="29" subjects_affected="23" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="8" subjects_affected="8" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary tract infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="5" subjects_affected="2" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="8" subjects_affected="5" subjects_at_risk="22"/>
                <counts group_id="E10" events="17" subjects_affected="15" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="55" subjects_affected="35" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="8" subjects_at_risk="47"/>
                <counts group_id="E20" events="7" subjects_affected="4" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="14" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vulvovaginal mycotic infection</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Injury, poisoning and procedural complications</title>
            <event_list>
              <event>
                <sub_title>Fall</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="3" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="7" subjects_affected="6" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Infusion related reaction</sub_title>
                <counts group_id="E1" events="3" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Scar</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Soft tissue injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Spinal column injury</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Investigations</title>
            <event_list>
              <event>
                <sub_title>Activated partial thromboplastin time prolonged</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Alanine aminotransferase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="25" subjects_affected="19" subjects_at_risk="304"/>
                <counts group_id="E11" events="20" subjects_affected="9" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="14" subjects_affected="6" subjects_at_risk="31"/>
                <counts group_id="E17" events="21" subjects_affected="17" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="7" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="9" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Aspartate aminotransferase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="26" subjects_affected="20" subjects_at_risk="304"/>
                <counts group_id="E11" events="30" subjects_affected="20" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="5" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="12" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E16" events="13" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="21" subjects_affected="17" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="6" subjects_affected="5" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="11" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="4" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood alkaline phosphatase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="21" subjects_affected="16" subjects_at_risk="304"/>
                <counts group_id="E11" events="14" subjects_affected="9" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="12" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="12" subjects_affected="11" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="6" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="4" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="8" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood bilirubin increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="12" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="8" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="6" subjects_affected="3" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="3" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="8" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood cholesterol increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="5" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood creatinine increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="21" subjects_affected="12" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="27" subjects_affected="21" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood electrolytes decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood fibrinogen increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood magnesium decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Blood thyroid stimulating hormone increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="10" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cortisol decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Gamma-glutamyltransferase increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="13" subjects_affected="12" subjects_at_risk="304"/>
                <counts group_id="E11" events="10" subjects_affected="8" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="5" subjects_affected="3" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="11" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E16" events="15" subjects_affected="7" subjects_at_risk="31"/>
                <counts group_id="E17" events="14" subjects_affected="11" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="7" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="10" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>International normalised ratio increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="5" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Transaminases increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vitamin d decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Weight decreased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="6" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="30" subjects_affected="24" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="8" subjects_affected="6" subjects_at_risk="31"/>
                <counts group_id="E17" events="19" subjects_affected="16" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="13" subjects_affected="9" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="7" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Weight increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="14" subjects_affected="9" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>White blood cell count increased</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Metabolism and nutrition disorders</title>
            <event_list>
              <event>
                <sub_title>Decreased appetite</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="3" subjects_affected="2" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="9" subjects_affected="7" subjects_at_risk="21"/>
                <counts group_id="E8" events="7" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="7" subjects_affected="4" subjects_at_risk="22"/>
                <counts group_id="E10" events="112" subjects_affected="80" subjects_at_risk="304"/>
                <counts group_id="E11" events="17" subjects_affected="15" subjects_at_risk="40"/>
                <counts group_id="E12" events="6" subjects_affected="6" subjects_at_risk="21"/>
                <counts group_id="E13" events="5" subjects_affected="5" subjects_at_risk="24"/>
                <counts group_id="E14" events="38" subjects_affected="22" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E16" events="12" subjects_affected="11" subjects_at_risk="31"/>
                <counts group_id="E17" events="60" subjects_affected="51" subjects_at_risk="201"/>
                <counts group_id="E18" events="5" subjects_affected="4" subjects_at_risk="20"/>
                <counts group_id="E19" events="17" subjects_affected="14" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="14" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dehydration</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="24" subjects_affected="18" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="11" subjects_affected="8" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="6" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="12" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="5" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Fluid intake reduced</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypercalcaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="7" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="19" subjects_affected="16" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="15" subjects_affected="10" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperglycaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="15" subjects_affected="12" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="7" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="6" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperkalaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="20" subjects_affected="15" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperuricaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="9" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypoalbuminaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="22" subjects_affected="20" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="4" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypocalcaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="6" subjects_affected="4" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="9" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypoglycaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypokalaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="29" subjects_affected="22" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="13" subjects_affected="11" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="6" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="6" subjects_affected="6" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypomagnesaemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="17" subjects_affected="13" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="15" subjects_affected="12" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="7" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="5" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="8" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyponatraemia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="49" subjects_affected="31" subjects_at_risk="304"/>
                <counts group_id="E11" events="8" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="3" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="5" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="25" subjects_affected="20" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="7" subjects_affected="6" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Iron deficiency</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Polydipsia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Musculoskeletal and connective tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Arthralgia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="3" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="9" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="62" subjects_affected="44" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="14" subjects_affected="9" subjects_at_risk="21"/>
                <counts group_id="E13" events="5" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="40" subjects_affected="25" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="15" subjects_affected="11" subjects_at_risk="47"/>
                <counts group_id="E20" events="6" subjects_affected="5" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="14" subjects_affected="9" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Back pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="7" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="4" subjects_affected="4" subjects_at_risk="22"/>
                <counts group_id="E10" events="56" subjects_affected="49" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="5" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="16" subjects_affected="13" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E16" events="8" subjects_affected="8" subjects_at_risk="31"/>
                <counts group_id="E17" events="44" subjects_affected="30" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="8" subjects_affected="8" subjects_at_risk="47"/>
                <counts group_id="E20" events="5" subjects_affected="4" subjects_at_risk="20"/>
                <counts group_id="E21" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="20" subjects_affected="14" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Coccydynia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Groin pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="6" subjects_affected="3" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Joint swelling</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Muscle spasms</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="10" subjects_affected="10" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Muscular weakness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="11" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Musculoskeletal chest pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="31" subjects_affected="25" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="9" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="8" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="4" subjects_affected="4" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Musculoskeletal pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="3" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="23" subjects_affected="18" subjects_at_risk="304"/>
                <counts group_id="E11" events="8" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="33" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="23" subjects_affected="16" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Myalgia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="41" subjects_affected="31" subjects_at_risk="304"/>
                <counts group_id="E11" events="5" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="7" subjects_affected="5" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="4" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="23" subjects_affected="14" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="6" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Neck pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pain in extremity</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="32" subjects_affected="26" subjects_at_risk="304"/>
                <counts group_id="E11" events="4" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="15" subjects_affected="11" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="4" subjects_affected="4" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pain in jaw</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Neoplasms benign, malignant and unspecified (incl cysts and polyps)</title>
            <event_list>
              <event>
                <sub_title>Cancer pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="3" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tumour pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="12" subjects_affected="10" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Nervous system disorders</title>
            <event_list>
              <event>
                <sub_title>Aphasia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Ataxia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dizziness</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="4" subjects_affected="2" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="7" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="24" subjects_affected="23" subjects_at_risk="304"/>
                <counts group_id="E11" events="6" subjects_affected="6" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="22" subjects_affected="9" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="4" subjects_at_risk="40"/>
                <counts group_id="E16" events="5" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="14" subjects_affected="11" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="5" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="9" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dizziness postural</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysarthria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysgeusia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="3" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Headache</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="2" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="2" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="3" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="8" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="46" subjects_affected="33" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="5" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="6" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="8" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E16" events="7" subjects_affected="7" subjects_at_risk="31"/>
                <counts group_id="E17" events="15" subjects_affected="10" subjects_at_risk="201"/>
                <counts group_id="E18" events="11" subjects_affected="9" subjects_at_risk="20"/>
                <counts group_id="E19" events="7" subjects_affected="6" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E22" events="14" subjects_affected="9" subjects_at_risk="62"/>
                <counts group_id="E23" events="5" subjects_affected="4" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hemiparesis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypoaesthesia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lethargy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nervous system disorder</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Neuropathy peripheral</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="5" subjects_affected="4" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Paraesthesia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Parosmia</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peripheral motor neuropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Peripheral sensory neuropathy</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Somnolence</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="3" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Syncope</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Taste disorder</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="6" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Tremor</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="7" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Psychiatric disorders</title>
            <event_list>
              <event>
                <sub_title>Anxiety</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="18" subjects_affected="16" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="7" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="9" subjects_affected="8" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Confusional state</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="4" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Depression</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="10" subjects_affected="10" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="3" subjects_affected="3" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="8" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Insomnia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="26" subjects_affected="24" subjects_at_risk="304"/>
                <counts group_id="E11" events="7" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="6" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="25" subjects_affected="13" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="22" subjects_affected="20" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="10" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Renal and urinary disorders</title>
            <event_list>
              <event>
                <sub_title>Acute kidney injury</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="14" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="6" subjects_affected="6" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Haematuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="28" subjects_affected="18" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="4" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nocturia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pollakiuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Polyuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Proteinuria</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="11" subjects_affected="9" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="3" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary incontinence</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Urinary tract pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Reproductive system and breast disorders</title>
            <event_list>
              <event>
                <sub_title>Pelvic pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="5" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Respiratory, thoracic and mediastinal disorders</title>
            <event_list>
              <event>
                <sub_title>Atelectasis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Cough</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="7" subjects_affected="4" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="11" subjects_affected="9" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="102" subjects_affected="77" subjects_at_risk="304"/>
                <counts group_id="E11" events="8" subjects_affected="7" subjects_at_risk="40"/>
                <counts group_id="E12" events="4" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E13" events="6" subjects_affected="5" subjects_at_risk="24"/>
                <counts group_id="E14" events="15" subjects_affected="12" subjects_at_risk="51"/>
                <counts group_id="E15" events="5" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E16" events="10" subjects_affected="8" subjects_at_risk="31"/>
                <counts group_id="E17" events="27" subjects_affected="24" subjects_at_risk="201"/>
                <counts group_id="E18" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="7" subjects_affected="6" subjects_at_risk="21"/>
                <counts group_id="E22" events="13" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E23" events="4" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dysphonia</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="15" subjects_affected="13" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dyspnoea</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="4" subjects_affected="3" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="21" subjects_affected="15" subjects_at_risk="62"/>
                <counts group_id="E9" events="5" subjects_affected="5" subjects_at_risk="22"/>
                <counts group_id="E10" events="100" subjects_affected="75" subjects_at_risk="304"/>
                <counts group_id="E11" events="10" subjects_affected="8" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="6" subjects_affected="6" subjects_at_risk="24"/>
                <counts group_id="E14" events="22" subjects_affected="17" subjects_at_risk="51"/>
                <counts group_id="E15" events="14" subjects_affected="10" subjects_at_risk="40"/>
                <counts group_id="E16" events="10" subjects_affected="9" subjects_at_risk="31"/>
                <counts group_id="E17" events="35" subjects_affected="27" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="10" subjects_affected="9" subjects_at_risk="47"/>
                <counts group_id="E20" events="5" subjects_affected="5" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E22" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dyspnoea exertional</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="9" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="4" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Haemoptysis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="4" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="29" subjects_affected="24" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="10" subjects_affected="8" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hiccups</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="8" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Nasal congestion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="2" subjects_affected="2" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="13" subjects_affected="10" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="3" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="4" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="4" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="9" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Oropharyngeal pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="8" subjects_affected="7" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="20" subjects_affected="17" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="9" subjects_affected="9" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pleural effusion</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="19" subjects_affected="14" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="5" subjects_affected="4" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pleuritic pain</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumonitis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pneumothorax</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Productive cough</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="23" subjects_affected="20" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="13" subjects_affected="10" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Respiratory distress</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Rhinorrhoea</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="2" subjects_affected="2" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="3" subjects_affected="3" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Sinus congestion</sub_title>
                <counts group_id="E1" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Sneezing</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Upper-airway cough syndrome</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Wheezing</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="17" subjects_affected="15" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Skin and subcutaneous tissue disorders</title>
            <event_list>
              <event>
                <sub_title>Acne</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dermatitis acneiform</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Dry skin</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E8" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="15" subjects_affected="14" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="3" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="7" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="3" subjects_affected="3" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="1" subjects_affected="1" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Erythema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="7" subjects_affected="6" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="6" subjects_affected="6" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="4" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="4" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Exfoliative rash</sub_title>
                <counts group_id="E1" events="2" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hyperhidrosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="5" subjects_affected="5" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="2" subjects_affected="2" subjects_at_risk="24"/>
                <counts group_id="E14" events="15" subjects_affected="5" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="2" subjects_affected="2" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Night sweats</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="8" subjects_affected="8" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="9" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="2" subjects_affected="2" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pemphigoid</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="0" subjects_affected="0" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="0" subjects_affected="0" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Petechiae</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="2" subjects_affected="2" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="1" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Pruritus</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="4" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="4" subjects_affected="3" subjects_at_risk="21"/>
                <counts group_id="E8" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E9" events="3" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="49" subjects_affected="35" subjects_at_risk="304"/>
                <counts group_id="E11" events="20" subjects_affected="16" subjects_at_risk="40"/>
                <counts group_id="E12" events="7" subjects_affected="5" subjects_at_risk="21"/>
                <counts group_id="E13" events="4" subjects_affected="4" subjects_at_risk="24"/>
                <counts group_id="E14" events="8" subjects_affected="6" subjects_at_risk="51"/>
                <counts group_id="E15" events="6" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E16" events="8" subjects_affected="5" subjects_at_risk="31"/>
                <counts group_id="E17" events="20" subjects_affected="15" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="10" subjects_affected="7" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="12" subjects_affected="10" subjects_at_risk="62"/>
                <counts group_id="E23" events="3" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Rash</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="4" subjects_affected="2" subjects_at_risk="4"/>
                <counts group_id="E3" events="3" subjects_affected="2" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="6" subjects_at_risk="62"/>
                <counts group_id="E9" events="2" subjects_affected="2" subjects_at_risk="22"/>
                <counts group_id="E10" events="54" subjects_affected="37" subjects_at_risk="304"/>
                <counts group_id="E11" events="7" subjects_affected="5" subjects_at_risk="40"/>
                <counts group_id="E12" events="7" subjects_affected="4" subjects_at_risk="21"/>
                <counts group_id="E13" events="12" subjects_affected="7" subjects_at_risk="24"/>
                <counts group_id="E14" events="13" subjects_affected="9" subjects_at_risk="51"/>
                <counts group_id="E15" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="6" subjects_affected="4" subjects_at_risk="31"/>
                <counts group_id="E17" events="28" subjects_affected="23" subjects_at_risk="201"/>
                <counts group_id="E18" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E19" events="2" subjects_affected="2" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="2" subjects_affected="2" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Rash maculo-papular</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="6" subjects_affected="4" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="13" subjects_affected="7" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="1" subjects_affected="1" subjects_at_risk="31"/>
                <counts group_id="E17" events="13" subjects_affected="5" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="5" subjects_affected="5" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Vitiligo</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="1" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="2" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E13" events="1" subjects_affected="1" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="2" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
          <category>
            <title>Vascular disorders</title>
            <event_list>
              <event>
                <sub_title>Deep vein thrombosis</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="1" subjects_affected="1" subjects_at_risk="22"/>
                <counts group_id="E10" events="3" subjects_affected="3" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="0" subjects_affected="0" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hot flush</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="1" subjects_affected="1" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="4" subjects_affected="4" subjects_at_risk="304"/>
                <counts group_id="E11" events="2" subjects_affected="2" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="3" subjects_affected="3" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypertension</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="1" subjects_affected="1" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="3" subjects_affected="1" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="16" subjects_affected="11" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="2" subjects_affected="2" subjects_at_risk="51"/>
                <counts group_id="E15" events="2" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="13" subjects_affected="7" subjects_at_risk="201"/>
                <counts group_id="E18" events="3" subjects_affected="3" subjects_at_risk="20"/>
                <counts group_id="E19" events="0" subjects_affected="0" subjects_at_risk="47"/>
                <counts group_id="E20" events="1" subjects_affected="1" subjects_at_risk="20"/>
                <counts group_id="E21" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="2" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Hypotension</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="0" subjects_affected="0" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E8" events="1" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="12" subjects_affected="12" subjects_at_risk="304"/>
                <counts group_id="E11" events="1" subjects_affected="1" subjects_at_risk="40"/>
                <counts group_id="E12" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="12" subjects_affected="10" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="3" subjects_affected="2" subjects_at_risk="21"/>
                <counts group_id="E22" events="3" subjects_affected="3" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
              <event>
                <sub_title>Lymphoedema</sub_title>
                <counts group_id="E1" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E2" events="0" subjects_affected="0" subjects_at_risk="4"/>
                <counts group_id="E3" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E4" events="0" subjects_affected="0" subjects_at_risk="3"/>
                <counts group_id="E5" events="1" subjects_affected="1" subjects_at_risk="6"/>
                <counts group_id="E6" events="0" subjects_affected="0" subjects_at_risk="7"/>
                <counts group_id="E7" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E8" events="0" subjects_affected="0" subjects_at_risk="62"/>
                <counts group_id="E9" events="0" subjects_affected="0" subjects_at_risk="22"/>
                <counts group_id="E10" events="1" subjects_affected="1" subjects_at_risk="304"/>
                <counts group_id="E11" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E12" events="1" subjects_affected="1" subjects_at_risk="21"/>
                <counts group_id="E13" events="0" subjects_affected="0" subjects_at_risk="24"/>
                <counts group_id="E14" events="1" subjects_affected="1" subjects_at_risk="51"/>
                <counts group_id="E15" events="0" subjects_affected="0" subjects_at_risk="40"/>
                <counts group_id="E16" events="0" subjects_affected="0" subjects_at_risk="31"/>
                <counts group_id="E17" events="2" subjects_affected="1" subjects_at_risk="201"/>
                <counts group_id="E18" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E19" events="1" subjects_affected="1" subjects_at_risk="47"/>
                <counts group_id="E20" events="0" subjects_affected="0" subjects_at_risk="20"/>
                <counts group_id="E21" events="0" subjects_affected="0" subjects_at_risk="21"/>
                <counts group_id="E22" events="2" subjects_affected="1" subjects_at_risk="62"/>
                <counts group_id="E23" events="0" subjects_affected="0" subjects_at_risk="10"/>
              </event>
            </event_list>
          </category>
        </category_list>
      </other_events>
    </reported_events>

    <certain_agreements>
      <pi_employee>Principal Investigators are NOT employed by the organization sponsoring the study.</pi_employee>
      <restrictive_agreement>MedImmune has 60 days to review results communications prior to public release and may delete information that compromises ongoing studies or is considered proprietary. This restriction is not intended to compromise the objective scientific integrity of the manuscript, it being understood that results shall be published regardless of outcome.</restrictive_agreement>
    </certain_agreements>
    <point_of_contact>
      <name_or_title>Ashok Gupta</name_or_title>
      <organization>MedImmune, LLC</organization>
      <phone>+13013981287</phone>
      <email>information.center@astrazeneca.com</email>
    </point_of_contact>
  </clinical_results>
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT01693562
org study id: CD-ON-MEDI4736-1108
nct id: NCT01693562
lead sponsor: 
has dmc: No
is fda regulated drug: Yes
is fda regulated device: No
This is a multicenter, open-label, first-time-in-human study with a standard 3+3
      dose-escalation phase in participants with advanced solid tumors followed by an expansion
      phase in participants with advanced solid tumors. An exploration cohort has been added to
      determine the safety using every 4 weeks (Q4W) dosing.
A dose-escalation and dose-expansion study of MEDI4736 (a monoclonal antibody that targets
      programmed cell death ligand-1 (PD-L1)) will evaluate the safety, tolerability,
      pharmacokinetics (PK), immunogenicity (IM), and antitumor activity of MEDI4736 in adult
      participants with solid tumors. A dose exploration cohort will look at the safety profile of
      Q4W dosing of MEDI4736.
allocation: N/A
intervention model: Single Group Assignment
primary purpose: Treatment
masking: None (Open Label)
measure: Number of Participants With Dose-limiting Toxicities in the Dose-escalation Phase
time frame: For MEDI4736 0.1 to MEDI4736 10 mg/kg arms: from Day 1 to Day 28 of first dose; for MEDI4736 15 mg/kg arm: from Day 1 to Day 42 of first dose
description: A DLT was defined as any Grade 3 or higher treatment-related toxicity that occurred during the DLT-evaluation period including any >= Grade 3 colitis or >= Grade 3 immune-related adverse event (irAE; AEs of immune nature in the absence of a clear alternative etiology) including rash, pruritus, or diarrhea that did not downgrade to =< Grade 2 within 3 days after onset of the event despite maximal supportive care including systemic corticosteroids. The DLT-evaluation period for 0.1 to 10 mg/kg arms was from Day 1 to Day 28 of first dose and for 15 mg/kg arm was from Day 1 to Day 42 of first dose.
measure: Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs) in the Dose-escalation, Dose-exploration, and Dose-expansion Phase
time frame: From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)
description: An adverse event (AE) is any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship. A serious adverse event (SAE) is an AE resulting in any of the following outcomes or deemed significant for any other reason: death; initial or prolonged inpatient hospitalization; life threatening experience (immediate risk of dying); persistent or significant disability/incapacity; congenital anomaly. The TEAEs are defined as events present at baseline that worsened in intensity after administration of study drug or events absent at baseline that emerged after administration of study drug.
measure: Number of Participants With Abnormal Clinical Laboratory Parameters Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase
time frame: From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)
description: Number of participants with abnormal clinical laboratory parameters reported as TEAEs are reported. Abnormal clinical laboratory parameters defined as any abnormal finding during analysis of coagulation, urine, hematology, and serum chemistry.
measure: Number of Participants With Abnormal Vital Signs Reported as TEAEs in the Dose-escalation, Dose-exploration, and Dose-expansion Phase
time frame: From Day 1 through 90 days after the last dose of study drug (approximately 5.25 years)
description: Number of participants with abnormal vital signs reported as TEAEs are reported. Abnormal vital signs are defined as any abnormal finding in the vital sign parameters (body weight, body temperature, blood pressure, pulse rate, and respiratory rate).
measure: Number of Participants With Change From Baseline in QT/QTc Interval in Local Electrocardiogram in the Dose-escalation, Dose-exploration, and Dose-expansion Phase
time frame: From Baseline (Day 1) through 90 days after the last dose of study drug (approximately 5.25 years)
description: Number of participants with change from baseline in notable QT/QTc interval in local electrocardiogram (ECG) are reported. The data for >0 participants with notable QT/QTc interval in local ECG from baseline are reported.
measure: Objective Response Rate (ORR) Assessed by Blinded Independent Central Review (BICR) in Participants With Non-squamous NSCLC Who Had Received 2 or More Prior Lines of Therapy in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The ORR assessed by BICR in participants with non-squamous NSCLC who had received 2 or more prior lines of therapy is reported. The ORR is defined as best overall response (BOR) of confirmed complete response (CR) or confirmed partial response (PR) based on Response Evaluation Criteria in Solid Tumours Version 1.1 (RECIST v1.1). The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.
measure: ORR Assessed by BICR in Participants With Squamous NSCLC Who Had Received 1 and 2 or More Prior Lines of Therapy in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The ORR assessed by BICR in participants with squamous NSCLC who had received 1 and 2 or more prior lines of therapy is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.
measure: ORR Assessed by BICR in Participants With UC Post-platinum (Programmed Cell Death Ligand [PD-L1] Status High) Who Had Received at Least 1 Line of Prior Therapy (2L+) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The ORR assessed by BICR in participants with UC post-platinum PD-L1 status high 2L+ is reported. The ORR is defined as BOR of confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.
measure: Area Under the Serum Concentration-time Curve up to the Last Measurable Concentration (AUClast) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase
time frame: After the first dose between Day 0 and Day 15 (Day 1 [pre and post dose] and predose of Dose 2 for all cohorts; Days 3, 5, 10 for Cohorts 0.1mg/kg to 10 mg/kg; Days 3, 5, 10, 15 for Cohort 15 mg/kg; Day 15 for Cohort 20 mg/kg)
description: Area under the concentration-time curve from time zero to the last measurable concentration (AUClast) of MEDI4736 is reported.
measure: Maximum Serum Concentration (Cmax) of MEDI4736 After the First Dose in the Dose-escalation and Dose-exploration Phase
time frame: After the first dose between Day 0 and Day 15 (Day 1 [pre and post dose] and predose of Dose 2 for all cohorts; Days 3, 5, 10 for Cohorts 0.1mg/kg to 10 mg/kg; Days 3, 5, 10, 15 for Cohort 15 mg/kg; Day 15 for Cohort 20 mg/kg)
description: The Cmax of MEDI4736 is reported.
measure: Number of Participants With Positive Anti-drug Antibodies (ADA) to MEDI4736 in the Dose-escalation, Dose-exploration Phase, and Dose-expansion Phase.
time frame: Escalation: Day1 of Dose(D)1 & D3, even numbered doses after D4; Exploration: Day1 of D1 & D2, even numbered doses after D2; Expansion: Day1 of D1, every 12 weeks since D3; all phases: till EOT, 30 days and 3 and 6 months post last dose (~5.25 years)
description: Number of participants with positive ADA titer to MEDI4736 are reported. Treatment-boosted ADA is defined as baseline positive ADA titer that was boosted to a 4-fold or higher level following drug administration; persistent positive is defined as positive at >= 2 post-baseline assessments (with >= 16 weeks between first and last positive) or positive at last post-baseline assessment; and transient positive is defined as having at least one post-baseline ADA-positive assessment and not fulfilling the condition of persistent positive.
measure: Number of Participants With Best Overall Response (BOR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The BOR assessed by BICR based on RECIST v1.1 in NSCLC and SCCHN cohorts is reported. The BOR includes CR, PR, stable disease (SD), progressive disease (PD), and non-evaluable (NE). The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.
measure: Number of Participants With BOR Assessed by Investigator in the Dose-escalation, Dose-exploration, and Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The BOR assessed by investigator based on RECIST v1.1 is reported. The BOR includes CR, PR, SD, PD, and NE. The CR is defined as disappearance of all target and non-target lesions and no new lesions. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. The PD is defined at least 20% increase in the sum of diameters of target lesions (compared to baseline) and/or new lesion. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression. The NE is defined as either when no or only a subset of lesion measurements are made at an assessment.
measure: Duration of Response (DoR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The DoR assessed by BICR in NSCLC and SCCHN cohorts is reported. The DoR is defined as the duration from the first documentation of objective response (OR) (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.
measure: DoR Assessed by Investigator in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The DoR in participants assessed by the investigator is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.
measure: Disease Control Rate (DCR) Assessed by BICR in NSCLC and SCCHN Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: Percentage of participants with disease control assessed by BICR in NSCLC and SCCHN cohorts is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.
measure: DCR Assessed by Investigator in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: Percentage of participants with disease control assessed by the investigator is reported. Disease control is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.
measure: Progression-free Survival (PFS) Assessed by BICR in NSCLC Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The PFS assessed by BICR in NSCLC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.
measure: PFS Assessed by BICR in SCCHN Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The PFS assessed by BICR in SCCHN cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.
measure: PFS Assessed by Investigator in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The PFS assessed by the investigator is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.
measure: OS in the Dose-Expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.
measure: ORR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The ORR assessed by BICR in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.
measure: ORR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The ORR assessed by the investigator in UC cohort is reported. The ORR is defined as confirmed CR or confirmed PR based on RECIST v1.1. The CR is defined as disappearance of all target and non-target lesions and no new lesions. A confirmed CR is defined as two CRs that were separated by at least 28 days with no evidence of progression in-between. The PR is defined as >= 30% decrease in the sum of diameters of target lesions (compared to baseline) and no new nontarget lesion. A confirmed PR is defined as two PRs or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between.
measure: DoR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The DoR assessed by BICR in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.
measure: DoR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The DoR assessed by investigator in UC cohort is reported. The DoR is defined as the duration from the first documentation of OR (confirmed CR or confirmed PR) to the first documented disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an un-confirmed CR that were separated by at least 4 weeks with no evidence of progression in-between. The DoR was estimated using Kaplan-Meier method.
measure: DCR Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: Percentage of participants with disease control assessed by BICR in UC cohort is reported. The DCR is defined as a BOR of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for disease progression.
measure: DCR Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: Percentage of participants with disease control assessed by investigator in UC cohort is reported. Disease control is defined as a best overall response of confirmed CR, confirmed PR, or SD based on RECIST v1.1. A confirmed CR is defined as two CRs (disappearance of all target and non-target lesions and no new lesions) that were separated by at least 28 days with no evidence of progression in-between. A confirmed PR is defined as two PRs (>= 30% decrease in the sum of diameters of target lesions compared to baseline and no new non-target lesion) or an un-confirmed PR and an unconfirmed CR that were separated by at least 28 days with no evidence of progression in-between. The SD is defined as neither sufficient shrinkage to qualify for PR not sufficient increase to qualify for disease progression.
measure: PFS Assessed by BICR in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The PFS assessed by BICR in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.
measure: PFS Assessed by Investigator in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The PFS assessed by the investigator in UC cohort is reported. The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.
measure: OS in UC Cohort (PD-L1 Low/Negative, Total, and PD-L1 High) in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The OS in UC cohort is reported. The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.
measure: Adjusted Comparison of PFS by PD-L1 Status in UC Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The PFS by PD-L1 status in UC cohort is reported. The PFS estimates are adjusted for baseline eastern cooperative oncology (ECOG), smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The PFS is defined as the time from the start of study treatment until the first documentation of disease progression based on RECIST v1.1 or death due to any cause, whichever occurred first. The PD is defined as at least a 20% increase in the sum of diameters of target lesions, taking as reference the smallest sum on study; the sum must also demonstrate an absolute increase of at least 5 mm. The appearance of one or more new lesions is also considered PD. The PFS was estimated using Kaplan-Meier method.
measure: Adjusted Comparison of OS by PD-L1 Status in UC Cohort in the Dose-expansion Phase
time frame: From Day 1 through disease progression, study withdrawal, or initiation of another anticancer therapy, whichever occurred first (approximately 5.25 years)
description: The OS by PD-L1 status in UC cohort is reported. The OS estimates are adjusted for baseline ECOG, smoking status, race, gender, age, previous lines of therapy, and liver metastasis. 95% CIs based on log (-log(survival)). The OS is defined as the time from the start of study treatment until death due to any cause. The OS was estimated using Kaplan-Meier method.
arm group label: Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)
arm group type: Experimental
description: Participants will receive intravenous (IV) infusion of MEDI4736 (durvalumab) 0.1 mg/kg every 2 weeks (Q2W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)
arm group type: Experimental
description: Participants will receive IV infusion of MEDI4736 0.3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Escalation Cohort (MEDI4736 1 mg/kg Q2W)
arm group type: Experimental
description: Participants will receive IV infusion of MEDI4736 1 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Escalation Cohort (MEDI4736 3 mg/kg Q2W)
arm group type: Experimental
description: Participants will receive IV infusion of MEDI4736 3 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Escalation Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Escalation Cohort (MEDI4736 15 mg/kg Q3W)
arm group type: Experimental
description: Participants will receive IV infusion of MEDI4736 15 mg/kg every 3 weeks (Q3W) in the dose-escalation phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Exploration Durvalumab 20 mg/kg (Q4W)
arm group type: Experimental
description: Participants will receive IV infusion of MEDI4736 20 mg/kg every 4 weeks (Q4W) in the dose-exploration phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with squamous cell carcinoma of the head and neck (SCCHN) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion Non-SCCHN Cohort HPV positive (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with non-SCCHN human papilloma virus positive (Non-SCCHN HPV+) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with non-small-cell lung cancer (NSCLC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with hepatocellular carcinoma (HCC Total) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with advance cutaneous melanoma (ACM) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with uveal melanoma (UM) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with gastroesophageal cancer (GEC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with triple-negative breast cancer (TNBC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with pancreatic adenocarcinoma (PAC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with urothelial carcinoma (UC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with glioblastoma multiforme (GBM) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with ovarian cancer (OC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with soft- tissue sarcoma (STS) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with small-cell lung cancer (SCLC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with microsatellite instability (MSI)-high cancer will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose-expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)
arm group type: Experimental
description: Participants with nasopharyngeal carcinoma (NPC) will receive IV infusion of MEDI4736 10 mg/kg Q2W in the dose- expansion phase for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
intervention type: Drug
intervention name: MEDI4736
description: Participants will receive IV infusion of MEDI4736 for maximum of 12 months or until confirmed progressive disease, initiation of alternative cancer therapy, unacceptable toxicity, withdrawal of consent, or development of other reason for treatment discontinuation, whichever occurs first.
arm group label: Escalation Cohort (MEDI4736 0.1 mg/kg Q2W)
arm group label: Escalation Cohort (MEDI4736 0.3 mg/kg Q2W)
arm group label: Escalation Cohort (MEDI4736 1 mg/kg Q2W)
arm group label: Escalation Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Escalation Cohort (MEDI4736 15 mg/kg Q3W)
arm group label: Escalation Cohort (MEDI4736 3 mg/kg Q2W)
arm group label: Expansion ACM Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion GBM Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion GEC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion HCC Total Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion MSI-high Cancer Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion NPC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion NSCLC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion Non-SCCHN Cohort HPV positive (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion OC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion PAC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion SCCHN Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion SCLC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion STS Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion TNBC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion UC Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Expansion UM Cohort (MEDI4736 10 mg/kg Q2W)
arm group label: Exploration Durvalumab 20 mg/kg (Q4W)
other name: Durvalumab
criteria: 
gender: All
minimum age: 18 Years
maximum age: 99 Years
healthy volunteers: No
last name: MedImmune, LLC
affiliation: MedImmune LLC
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country: Belgium
country: Canada
country: France
country: Germany
country: Italy
country: Korea, Republic of
country: Taiwan
country: United Kingdom
country: United States
url: https://filehosting-v2.pharmacm.com/api/Attachment/Download?tenantId=80217111&amp;parentIdentifier=CD-ON-MEDI4736-1108&amp;attachmentIdentifier=4cfe3393-2ef4-499b-af69-233e9ad1c75e&amp;fileName=cd-on-medi4736-1108-csp-amendment-9-redacted_20201207.pdf&amp;versionIdentifier=
description: CSP amendment
url: https://filehosting-v2.pharmacm.com/api/Attachment/Download?tenantId=80217111&amp;parentIdentifier=CD-ON-MEDI4736-1108&amp;attachmentIdentifier=b10f44de-43f5-4ffd-b0aa-5f4544600b45&amp;fileName=cd-on-medi4736-1108-sap-ed-6-redacted_Redacted_20201207.pdf&amp;versionIdentifier=
description: SAP redacted
responsible party type: Sponsor
mesh term: Durvalumab
provided document: 
provided document: 
participant flow: 
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reported events: 
certain agreements: 
point of contact: 