<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT01689012</url>
  </required_header>
  <id_info>
    <org_study_id>STU68255</org_study_id>
    <nct_id>NCT01689012</nct_id>
  </id_info>
  <brief_title>The Effect of Facial Exercise on the Appearance of Aging</brief_title>
  <official_title>A Pilot Study of the Efficacy of a Facial Exercise Program</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Northwestern University</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>Northwestern University</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
  </oversight_info>
  <brief_summary>
    <textblock>
      This study seeks to evaluate the effects of facial exercises on aging of the face.&#xD;
    </textblock>
  </brief_summary>
  <overall_status>Completed</overall_status>
  <start_date>September 2012</start_date>
  <completion_date type="Actual">June 2013</completion_date>
  <primary_completion_date type="Actual">June 2013</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>N/A</allocation>
    <intervention_model>Single Group Assignment</intervention_model>
    <primary_purpose>Prevention</primary_purpose>
    <masking>Single (Outcomes Assessor)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Improvement of face and neck after facial exercise compared to baseline</measure>
    <time_frame>up to 20 weeks</time_frame>
  </primary_outcome>
  <number_of_arms>1</number_of_arms>
  <enrollment type="Actual">27</enrollment>
  <condition>Aging</condition>
  <arm_group>
    <arm_group_label>Facial Exercise</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Facial Exercise</intervention_name>
    <arm_group_label>Facial Exercise</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Aged 40-65 years&#xD;
&#xD;
          -  No significant medical illness&#xD;
&#xD;
          -  No chronic smokers&#xD;
&#xD;
          -  Subject with mild to moderate facial atrophy&#xD;
&#xD;
          -  Subjects who provide and interest and who understand the importance of consistently&#xD;
             executing the program daily.&#xD;
&#xD;
          -  Subjects with the willingness and ability to understand and provide informed consent.&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Under 40 years of age, Over 65 years of age&#xD;
&#xD;
          -  Pregnant or lactating&#xD;
&#xD;
          -  Subjects who have ever had any invasive cosmetic procedure, including facelifts, neck&#xD;
             lifts, laser resurfacing, dermabrasion, or liposuction&#xD;
&#xD;
          -  Subjects who have non-invasive or minimally invasive cosmetic procedures, such a&#xD;
             non-ablative lasers, medium-depth or deeper chemical peels, injectable neurotoxins or&#xD;
             fillers, within the past year.&#xD;
&#xD;
          -  Subjects who have used topical or oral retinoids within the past year.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>40 Years</minimum_age>
    <maximum_age>65 Years</maximum_age>
    <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Murad Alam, MD</last_name>
    <role>Principal Investigator</role>
    <affiliation>Northwestern University</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Northwestern University Feinberg School of Medicine, Department of Dermatology</name>
      <address>
        <city>Chicago</city>
        <state>Illinois</state>
        <zip>60611</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>United States</country>
  </location_countries>
  <verification_date>December 2021</verification_date>
  <study_first_submitted>September 14, 2012</study_first_submitted>
  <study_first_submitted_qc>September 14, 2012</study_first_submitted_qc>
  <study_first_posted type="Estimate">September 20, 2012</study_first_posted>
  <last_update_submitted>December 2, 2021</last_update_submitted>
  <last_update_submitted_qc>December 2, 2021</last_update_submitted_qc>
  <last_update_posted type="Actual">December 6, 2021</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>Northwestern University</investigator_affiliation>
    <investigator_full_name>Murad Alam</investigator_full_name>
    <investigator_title>Professor in Dermatology, Otolaryngology- Head and Neck Surgery, and Surgery-Organ Transplantation</investigator_title>
  </responsible_party>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT01689012
org study id: STU68255
nct id: NCT01689012
lead sponsor: 
has dmc: No
This study seeks to evaluate the effects of facial exercises on aging of the face.
allocation: N/A
intervention model: Single Group Assignment
primary purpose: Prevention
masking: Single (Outcomes Assessor)
measure: Improvement of face and neck after facial exercise compared to baseline
time frame: up to 20 weeks
arm group label: Facial Exercise
arm group type: Experimental
intervention type: Behavioral
intervention name: Facial Exercise
arm group label: Facial Exercise
criteria: 
gender: All
minimum age: 40 Years
maximum age: 65 Years
healthy volunteers: Accepts Healthy Volunteers
last name: Murad Alam, MD
role: Principal Investigator
affiliation: Northwestern University
facility: 
country: United States
responsible party type: Principal Investigator
investigator affiliation: Northwestern University
investigator full name: Murad Alam
investigator title: Professor in Dermatology, Otolaryngology- Head and Neck Surgery, and Surgery-Organ Transplantation