3D similarity search software [closed]








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What software / webservice can one use to find a compound that has similar 3D structure/dimension to another compound?


eg. say we are tying to find a 'better' version of atropine, so naturally we try to find compound with similar 3D structure to [Atropine](https://en.wikipedia.org/wiki/Atropine) (antimuscarinic)


and [3d structure of atropine](https://pubchem.ncbi.nlm.nih.gov/compound/174174#section=Top) (and all other drugs) is available 


so what software can we run to search 3d shape look-alike of atropine among all available 3d structures ?


similar shape and size for starter?


[![atropine-3d-structure](https://i.stack.imgur.com/QTkRw.png)](https://i.stack.imgur.com/QTkRw.png)


