What does penicillin react with? [closed]








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Just wondering what penicillin reacts with and if so, can you please write a word equation.
I've tried to do some research on it but had no luck. would mean a lot if someone could help me out 




To begin with, first pull up a structure of Penicillin (Image is in public domain):


[![enter image description here](https://i.stack.imgur.com/ppymX.png)](https://i.stack.imgur.com/ppymX.png)


Next, try to identify some of the functional groups, as an example I've marked two of them: one in yellow and one in blue.


[![enter image description here](https://i.stack.imgur.com/eQWO8.jpg)](https://i.stack.imgur.com/eQWO8.jpg)


The one which is marked in yellow is carboxylic acid ($\ce{R-COOH}$) and the blue one is an (secondary) amide ($\ce{R-NH-CO-R'}$). Do you remember any of the substances that react with these two groups? Some of the reactions you can think of are (I'm listing these for carboxylic acid, try thinking about amide yourself):


* Sodium metal test
* Acid base reactions (neutralization)
* Decarboxylation reactions
* Schmidt reaction ($\ce{R-COOH + HN3 -> R-NH2}$)
* Reduction of acid to alcohol


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