L Kruskal-Wallis test post hoc: uncorrected Dunn's test CTL: 12 Unmediated MDD: 8 Medicated MDD: 5 K-W test: P = 0.0096 (approximate) CTL vs. Unmedicated MDD: P = 0.0064 CTL vs. Medicated MDD: P = 0.0269

Keywords: Fisher's LSD CTL: 10 SUS: 15 RES: 11 Fisher's LSD CTL: 15 Unmediated MDD: 4 Medicated MDD: 5 ANOVA: P = 0, 0362 CTL vs, Unmedicated MDD: P = 0, 0407 CTL vs, Medicated MDD: P = 0, 0391 ANOVA: F (2, 21) = 3, 904 CTL vs, Unmedicated MDD: t (21) = 2, 18 CTL vs, Medicated MDD: t ( 21) = 2, 201

Interaction: F (1, 32) = 5.789 VGF level: F (1, 32) = 12.33 Target: F (1, 32) = 16.84 Wildtype Defeated/Target absent vs. Wildtype Defeated/Target present: t (32) = 1.47 Wildtype Defeated/Target absent vs. Syn-Cre, KO Defeated/Target absent: t (32) = 0.7811 Syn-Cre, KO Defeated/Target absent vs. Syn-Cre, KO Defeated/Target present: t (32) = 3.986 Wildtype Defeated/Target present vs. Syn-Cre, KO Defeated/Target present: t (32) = 4.184 


Fisher

  /Saline vs. AAV-GFP/Ketamine: P = 0.0158 AAV-GFP/Saline vs. AAV-CreGFP/Saline: P = 0.5682 AAV-CreGFP/Saline vs. AAV-CreGFP/Saline vs. AAV-GFP/Ketamine: t (15) = 2.72 AAV-GFP/Saline vs. AAV-CreGFP/Saline: t (15) = 0.5835 AAV-CreGFP/Saline vs. AAV-CreGFP/Saline vs. AAV-GFP/Ketamine: t (16) = 2.506 AAV-GFP/Saline vs. AAV-CreGFP/Saline: t (16) = 1.341 AAV-CreGFP/Saline vs. AAV-CreGFP/Ketamine: t (16) = 1.521 AAV-GFP/Ketamine vs. AAV-CreGFP/Ketamine: t (16) = 2/SC-62 vs. AAV-GFP/TLQP-62: t (32) = 3.035 AAV-GFP/SC-62 vs. AAV-CreGFP/SC-62: t (32) = 0.05584 AAV-CreGFP/SC-62 vs. AAV-CreGFP/TLQP--62 vs. Saline/TLQP-62: P = 0.0032 Saline/SC-62 vs. NBQX/SC-62: P = 0.9322 NBQX/SC-62 vs. NBQX/TLQP-62: P = 0.4848 Saline/TLQP-62 vs. NBQX/TLQP-62: P -62 vs. Saline/TLQP-62: t (18) = 3.402 Saline/SC-62 vs. NBQX/SC-62: t (18) = 0.08632 NBQX/SC-62 vs. NQBX/TLQP-62: t (18) = 0.7133 Saline/TLQP-62 vs. NBQX/TLQP-62: t -62 vs. Saline/TLQP 


Peptide: F (1, 9) = 1.763 AAV-GFP/SC-62 vs. AAV-GFP/TLQP-62: t (9) = 1.933 (Fisher's LSD); t (4) = 3.758 (Student's t test) AAV-GFP/SC-62 vs. AAV-CreGFP/SC-62: t (9) = 0.7598 AAV-CreGFP/SC-62 vs. AAV-CreGFP/TLQP-62: t (9) = 0.1231 AAV-GFP/TLQP-62 vs. AAV-CreGFP/TLQP-62: t (9) = 3.002
Fisher's Lsd
L Kruskal-Wallis test post hoc: uncorrected Dunn's test CTL: 12 Unmediated MDD: 8 Medicated MDD: 5 K-W test: P = 0.0096 (approximate) CTL vs. Unmedicated MDD: P = 0.0064 CTL vs. Medicated MDD: P = 0.0269