Table S1 . ASOs used in this study

 S1 

	ASO name	Length Sequence 5'-3'	Chemistry
	ASO1-cEt/DNA	18 nt	AGGCGGCGGAGTTCCTCA	kkddkddkddkddkddkk
	ASO2-cEt/DNA	16 nt	GAGGACGATTATGGCC	kkddkddkddkddkddkk
	Ctrl-cEt/DNA	18 nt	CGGATGAGTGCCTGCAAT	kkddkddkddkddkddkk
	mASO3-cEt/DNA	16 nt	ACTTGGTGAGCACGAT	kddkddkddkddkddk
	mASO3-GN3-cEt/DNA	16 nt	ACTTGGTGAGCACGAT	5'GalNAc3-kddkddkddkddkddk
	Base modification: k = constrained ethyl (cEt) base modification; d = DNA base; ligand conjugation:
	GalNAc3 = triantennary N-acetylgalactosamine; all ASOs have uniform P=S backbone and 5-methyl-C
	modifications