Yes Yes Yes No Yes Yes No No No No No No Yes Yes Yes No No Yes No Yes No No Yes No No No No No No No No Yes No No No No No No No No Yes No No No No Yes No No No Yes Yes No Yes No No No No Yes No Yes No No No Yes No No Yes No No Yes No No No No No No No No No No No No No No No No No Yes Yes Yes Yes No No No No No No No No No No No No Yes Yes No No No No Yes No Yes No No Yes No No No No No Yes Yes No No No Yes No No Yes Yes No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No Yes No No No No No No No No No No No No No No No No No No No No No No No No No Yes No No No No No No No No No Yes No No No No No Yes Yes Yes No Yes No No Yes No No No No Yes No No No No No No Yes Yes Yes Yes Yes Yes No No No No No Yes Yes Yes No No No No No Yes No No No No No Yes Yes Yes No No No No No No No No No No Yes No No No No No No No No No No No No No No No No No Yes No No No Yes Yes Yes Yes Yes No Yes Yes Yes Yes Yes No No No No No No No No No No No 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Yes Yes No No No No No Yes Yes Yes Yes No No No No No No No No No No No No Yes Yes No No Yes No Yes No No Yes No No No No No No No No No No No No Yes Yes No Yes Yes No Yes Yes Yes Yes No Yes No No Yes Yes No No No No No Yes Yes No Yes No No Yes Yes No No No Yes No No No No No No No No No Yes No Yes Yes No No No No Yes Yes No No No No No No No Yes Yes No No Yes Yes No No No Yes No No No No No No Yes No Yes Yes Yes No No No Yes Yes No Yes No No No No No Yes No No No No No No No No No Yes Yes Yes No Yes Yes Yes Yes No No No No No No No No No No No No Yes Yes Yes Yes No No No No No No No No No No No Yes No No No No Yes No No No No No No No Yes Yes Yes Yes No No Yes Yes No No No No Yes No Yes No No No No No No No No No Yes No No Yes No No No Yes Yes Yes Yes Yes No No No No No No No No No Yes No No No No No No No No No No No No No No No No No No No No No No No No No No Yes No No No No No No No No No No No No No No No No No No No No No No Yes No No Yes Yes Yes No No No Yes No No No No No No 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Chromosomal replication initiator protein DnaA DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase) DNA replication and repair protein RecF (single-strand DNA binding protein) Conserved hypothetical protein DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) Possible conserved membrane protein Possible membrane protein Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (rotamase A) Probable conserved membrane protein Probable conserved transmembrane protein Probable conserved membrane protein Possible anthranilate synthase component II TrpG (glutamine amidotransferase) Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) Probable penicillin-binding protein PbpA Probable cell division protein RodA Phosphoserine/threonine phosphatase PstP Conserved protein with FHA domain, FhaB Conserved protein with FHA domain, FhaA Conserved hypothetical protein Probable transcriptional regulatory protein WhiB-like WhiB5 Possible transcriptional regulatory protein Putative secreted protein P60-related protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Possible remnant of a transposase Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase) Probable acyl carrier protein AcpA (ACP) Conserved hypothetical protein Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved protein Probable conserved integral membrane protein Conserved protein Possible conserved transmembrane protein Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen) Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS) Possible transcriptional regulatory protein (probably MarR-family) Probable transcriptional regulatory protein (probably GntR-family) Possible oxidoreductase Possible hydrolase myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (glucose 6-phosphate cyclase) (glucocycloaldolase) Conserved protein Possible membrane protein Conserved hypothetical protein Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase (peptidoglycan TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase) Probable conserved transmembrane protein Conserved protein 30S ribosomal protein S6 RpsF Single-strand binding protein Ssb (helix-destabilizing protein) 30S ribosomal protein S18-1 RpsR1 50S ribosomal protein L9 RplI Hypothetical protein Rv0057 Probable replicative DNA helicase DnaB Hypothetical protein Rv0059 Conserved hypothetical protein Hypothetical protein Rv0061c Possible cellulase CelA1 (endoglucanase) (endo-1,4-beta-glucanase) (FI-cmcase) (carboxymethyl cellulase) Possible oxidoreductase Probable conserved transmembrane protein Possible antitoxin VapB1 Possible toxin VapC1 Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Possible transcriptional regulatory protein (possibly TetR-family) Probable oxidoreductase Probable L-serine dehydratase SdaA (L-serine deaminase) (SDH) (L-SD) Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) Possible maturase Probable glutamine-transport transmembrane protein ABC transporter Probable glutamine-transport ATP-binding protein ABC transporter Conserved protein Probable aminotransferase Probable membrane protein Probable oxidoreductase Probable transcriptional regulatory protein Hypothetical protein Rv0078A Conserved protein Unknown protein Conserved hypothetical protein Probable transcriptional regulatory protein Probable oxidoreductase Probable oxidoreductase Possible formate hydrogenlyase HycD (FHL) Possible hydrogenase HycP Possible hydrogenase HycQ Possible formate hydrogenase HycE (FHL) Possible polyketide cyclase/dehydrase Possible methyltransferase/methylase Possible membrane protein Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase) + S-adenosylhomocysteine nucleosidase (S-adenosyl-L-homocysteine homocysteinylribohydrolase) Cation transporter P-type ATPase a CtpA Probable conserved membrane protein Conserved hypothetical protein Conserved hypothetical protein PPE family protein PPE1 Possible oxidoreductase Probable fatty acyl CoA thioesterase type III FcoT Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved hypothetical protein Probable peptide synthetase Nrp (peptide synthase) Probable conserved integral membrane protein Probable cation-transporter P-type ATPase B CtpB Conserved hypothetical protein 50S ribosomal protein L28-1 RpmB1 Conserved hypothetical protein Probable cation-transporter ATPase I CtpI Hypothetical protein Rv0108c PE-PGRS family protein PE_PGRS1 Probable conserved integral membrane protein Possible transmembrane acyltransferase Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase) Probable sedoheptulose-7-phosphate isomerase GmhA (phosphoheptose isomerase) Possible D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB (D-glycero-D-manno-heptose 7-phosphate kinase) Possible D-alpha-D-heptose-7-phosphate kinase HddA Probable L,D-transpeptidase LdtA Oxidative stress response regulatory protein OxyS Probable oxalyl-CoA decarboxylase OxcA Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable elongation factor G FusA2 (EF-G) Conserved protein Hypothetical protein Rv0122 Unknown protein PE-PGRS family protein PE_PGRS2 Probable serine protease PepA (serine proteinase) (MTB32A) Trehalose synthase TreS Maltokinase Mak Probable conserved transmembrane protein Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) Probable 3-hydroxyl-thioester dehydratase Probable acyl-CoA dehydrogenase FadE1 Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2 GCN5-related N-acetyltransferase Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) Possible transcriptional regulatory protein Probable cytochrome P450 138 Cyp138 Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide reductase) (peptide met(O) reductase) Conserved hypothetical protein Possible oxidoreductase Conserved protein Unknown protein Conserved hypothetical protein Probable conserved transmembrane protein Probable transcriptional regulatory protein (possibly TetR-family) Possible S-adenosylmethionine-dependent methyltransferase Possible S-adenosylmethionine-dependent methyltransferase Probable aldehyde dehydrogenase (NAD+) dependent Probable short-chain type dehydrogenase/reductase Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) Conserved hypothetical protein PE family protein PE1 PE family protein PE2 Phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase) (PTPase) Probable acyl-CoA dehydrogenase FadE2 Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic part] (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha) Probable NAD(P) transhydrogenase (subunit alpha) PntAb [second part; integral membrane protein] (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha) Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] (pyridine nucleotide transhydrogenase subunit beta) (nicotinamide nucleotide transhydrogenase subunit beta) Conserved protein Probable transcriptional regulatory protein (possibly TetR-family) PE family protein PE3 PE family protein PE4 Possible oxidoreductase Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 Conserved protein Conserved protein TB18.5 Probable transcriptional regulatory protein Mce1R (probably GntR-family) Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved integral membrane protein YrbE1A Conserved integral membrane protein YrbE1B Mce-family protein Mce1A Mce-family protein Mce1B Mce-family protein Mce1C Mce-family protein Mce1D Possible Mce-family lipoprotein LprK (Mce-family lipoprotein Mce1E) Mce-family protein Mce1F Probable conserved Mce associated membrane protein Probable conserved Mce associated transmembrane protein Probable conserved Mce associated protein Probable conserved Mce associated membrane protein Possible lipoprotein LprO Probable conserved transmembrane protein Conserved hypothetical protein Probable alternative RNA polymerase sigma factor SigG (RNA polymerase ECF type sigma factor) Possible lysophospholipase Conserved hypothetical protein Conserved hypothetical protein Probable beta-glucosidase BglS (gentiobiase) (cellobiase) (beta-D-glucoside glucohydrolase) Metallothionein, MymT Probable O-methyltransferase Probable conserved transmembrane protein Probable dihydroxy-acid dehydratase IlvD (dad) Conserved protein Probable conserved integral membrane protein Conserved hypothetical protein Conserved secreted protein Hypothetical protein Rv0193c Probable transmembrane multidrug efflux pump Possible two component transcriptional regulatory protein (probably LuxR-family) Possible transcriptional regulatory protein Possible oxidoreductase Probable zinc metalloprotease Zmp1 Probable conserved membrane protein Possible conserved transmembrane protein Conserved protein Probable conserved transmembrane transport protein MmpL11 Possible exported protein Probable conserved transmembrane protein Probable conserved transmembrane protein Possible conserved transmembrane transport protein MmpL3 Conserved hypothetical protein Hypothetical methlytransferase (methylase) Hypothetical protein Rv0209 Hypothetical protein Rv0210 Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA (phosphoenolpyruvate carboxylase) (PEPCK)(pep carboxykinase) Possible transcriptional regulatory protein NadR (probably AsnC-family) Possible methyltransferase (methylase) Probable fatty-acid-CoA ligase FadD4 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable acyl-CoA dehydrogenase FadE3 Double hotdog hydratase Possible esterase LipW Probable conserved transmembrane protein Probable conserved transmembrane protein Probable esterase LipC Possible triacylglycerol synthase (diacylglycerol acyltransferase) Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable aldehyde dehydrogenase Possible methyltransferase (methylase) Possible conserved protein Probable conserved transmembrane protein Probable conserved membrane protein Probable integral membrane acyltransferase Possible conserved membrane protein with PIN domain Probable phosphotriesterase Php (parathion hydrolase) (PTE) (aryldialkylphosphatase) (paraoxonase) (a-esterase) (aryltriphosphatase) (paraoxon hydrolase) Probable acyl-CoA dehydrogenase FadE4 Probable transcriptional regulatory protein (probably TetR/AcrR-family) Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 Probable conserved transmembrane protein Possible arabinofuranosyltransferase AftD Small secreted protein Probable conserved lipoprotein LpqI Possible transcriptional regulatory protein (probably TetR-family) Possible antitoxin VapB24 Possible toxin VapC24. Contains PIN domain Probable 3-hydroxyacyl-thioester dehydratase HtdX Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG4 (3-ketoacyl-acyl carrier protein reductase) Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (beta-ketothiolase) Probable acyl-CoA dehydrogenase FadE5 Possible oxidoreductase Probable conserved integral membrane protein Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase) Conserved protein Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A) Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB Probable nitrite reductase [NAD(P)H] small subunit NirD Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanylyltransferase Probable cobyric acid synthase CobQ1 PPE family protein PPE2 Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Possible transcriptional regulatory protein Probable integral membrane nitrite extrusion protein NarK3 (nitrite facilitator) Aminoglycoside 2'-N-acetyltransferase Aac (Aac(2')-IC) Conserved hypothetical protein Conserved hypothetical protein Probable periplasmic iron-transport lipoprotein Probable 5-oxoprolinase OplA (5-oxo-L-prolinase) (pyroglutamase) (5-OPASE) Probable integral membrane nitrite extrusion protein NarU (nitrite facilitator) Hypothetical protein Rv0268c Conserved hypothetical protein Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable acyl-CoA dehydrogenase FadE6 Unknown protein Possible transcriptional regulatory protein Conserved protein Possible transcriptional regulatory protein (possibly TetR-family) Conserved hypothetical protein Possible toxin VapC25. Contains PIN domain PE-PGRS family protein PE_PGRS3 PE-PGRS family protein PE_PGRS4 PPE family protein PPE3 Possible S-adenosylmethionine-dependent methyltransferase ESX conserved component EccA3. ESX-3 type VII secretion system protein ESX conserved component EccB3. ESX-3 type VII secretion system protein. Possible membrane protein ESX conserved component EccC3. ESX-3 type VII secretion system protein. Possible membrane protein PE family protein PE5 PPE family protein PPE4 ESAT-6 like protein EsxG (conserved protein TB9.8) Low molecular weight protein antigen 7 EsxH (10 kDa antigen) (CFP-7) (protein TB10.4) ESX-3 secretion-associated protein EspG3 ESX conserved component EccD3. ESX-3 type VII secretion system protein. Probable transmembrane protein Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) ESX conserved component EccE3. ESX-3 type VII secretion system protein. Probable transmembrane protein Conserved protein Probable trans-aconitate methyltransferase Tam Conserved protein Probable sulfatase PE-PGRS family protein PE_PGRS5 Hypothetical protein Rv0298 Hypothetical protein Rv0299 Possible antitoxin VapB2 Possible toxin VapC2 Probable transcriptional regulatory protein (probably TetR/AcrR-family) Probable dehydrogenase/reductase PPE family protein PPE5 PPE family protein PPE6 Putative oxidoreductase Unknown protein Probable conserved integral membrane protein Possible conserved exported protein Conserved protein Unknown protein Conserved hypothetical proline and threonine rich protein Conserved protein Possible conserved membrane protein Possible beta-1,3-glucanase precursor Possible muconolactone isomerase Possible glycerophosphoryl diester phosphodiesterase GlpQ2 (glycerophosphodiester phosphodiesterase) Probable conserved integral membrane protein Probable pyrrolidone-carboxylate peptidase Pcp (5-oxoprolyl-peptidase) (pyroglutamyl-peptidase I) (PGP-I) (pyrase) Possible conserved exported protein Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase) Probable UDP-glucose 6-dehydrogenase UdgA (UDP-GLC dehydrogenase) (UDP-GLCDH) (UDPGDH) Conserved hypothetical protein Possible transcriptional regulatory protein (possibly ArsR-family) Hypothetical protein Rv0325 Hypothetical protein Rv0326 Possible cytochrome P450 135A1 Cyp135A1 Possible transcriptional regulatory protein (possibly TetR/AcrR-family) Conserved hypothetical protein Hypothetical protein Rv0330c Possible dehydrogenase/reductase Conserved protein Unknown protein Alpha-D-glucose-1-phosphate thymidylyltransferase RmlA (dTDP-glucose synthase) (dTDP-glucose pyrophosphorylase) PE family protein PE6 Conserved 13E12 repeat family protein Probable aspartate aminotransferase AspC (transaminase A) (ASPAT) Probable iron-sulfur-binding reductase Possible transcriptional regulatory protein Conserved protein Isoniazid inductible gene protein IniB Isoniazid inductible gene protein IniA Isoniazid inductible gene protein IniC Probable lipoprotein LpqJ Conserved hypothetical protein Possible L-asparagine permease AnsP2 (L-asparagine transport protein) Probable conserved membrane protein Possible transcriptional regulatory protein Hypothetical protein Rv0349 Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa protein) (HSP70) Probable GrpE protein (HSP-70 cofactor) Probable chaperone protein DnaJ1 Probable heat shock protein transcriptional repressor HspR (MerR family) PPE family protein PPE7 PPE family protein PPE8 Conserved protein Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsase) Conserved protein Probable conserved integral membrane protein Conserved protein Probable conserved membrane protein Possible Mg2+ transport transmembrane protein MgtE Probable fructose-bisphosphate aldolase Fba Possible conserved transmembrane protein Conserved protein Conserved hypothetical protein Hypothetical protein Rv0367c Conserved hypothetical protein Possible membrane oxidoreductase Possible oxidoreductase Conserved hypothetical protein Conserved hypothetical protein Probable carbon monoxyde dehydrogenase (large chain) Probable carbon monoxyde dehydrogenase (small chain) Probable carbon monoxyde dehydrogenase (medium chain) Conserved hypothetical protein Probable transcriptional regulatory protein (probably LysR-family) Conserved hypothetical glycine rich protein Possible protein transport protein SecE2 Possible RNA methyltransferase (RNA methylase) Hypothetical protein Rv0381c Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) Possible conserved secreted protein Probable endopeptidase ATP binding protein (chain B) ClpB (ClpB protein) (heat shock protein F84.1) Probable monooxygenase Probable transcriptional regulatory protein (probably LuxR/UhpA-family) Conserved hypothetical protein PPE family protein PPE9 Probable phosphoribosylglycinamide formyltransferase 2 PurT (GART 2) (gar transformylase 2) (5'-phosphoribosylglycinamide transformylase 2) (formate-dependent gar transformylase) Conserved protein Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) Probable membrane NADH dehydrogenase NdhA Conserved 13E12 repeat family protein Possible secreted protein Hypothetical protein Rv0395 Hypothetical protein Rv0396 Conserved 13E12 repeat family protein Conserved protein Possible secreted protein Possible conserved lipoprotein LpqK Acyl-CoA dehydrogenase FadE7 Probable conserved transmembrane protein Probable conserved transmembrane transport protein MmpL1 Probable conserved membrane protein MmpS1 Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Probable membrane bound polyketide synthase Pks6 Beta lactamase like protein F420-dependent glucose-6-phosphate dehydrogenase Fgd1 Probable phosphate acetyltransferase Pta (phosphotransacetylase) Probable acetate kinase AckA (acetokinase) Serine/threonine-protein kinase PknG (protein kinase G) (STPK G) Probable glutamine-binding lipoprotein GlnH (GLNBP) Possible conserved membrane protein Possible mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) Thiamine-phosphate pyrophosphorylase ThiE (TMP pyrophosphorylase) (TMP-PPASE) (thiamine-phosphate synthase) Possible thiamine biosynthesis oxidoreductase ThiO Possible protein ThiS Probable thiamin biosynthesis protein ThiG (thiazole biosynthesis protein) Probable lipoprotein aminopeptidase LpqL Possible lipoprotein peptidase LpqM Possible transmembrane protein Conserved hypothetical protein Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) Probable thiamine biosynthesis protein ThiC Hypothetical protein Rv0424c Possible metal cation transporting P-type ATPase CtpH Possible transmembrane protein Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) GCN5-related N-acetyltransferase Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) Conserved hypothetical protein Putative tuberculin related peptide Periplasmic superoxide dismutase [Cu-Zn] SodC Conserved hypothetical protein Conserved hypothetical protein Putative conserved ATPase Probable CDP-diacylglycerol--serine O-phosphatidyltransferase PssA (PS synthase) (phosphatidylserine synthase) Possible phosphatidylserine decarboxylase Psd (PS decarboxylase) Probable molybdopterin biosynthesis protein MoeA2 Probable dehydrogenase/reductase 60 kDa chaperonin 2 GroEL2 (protein CPN60-2) (GroEL protein 2) (65 kDa antigen) (heat shock protein 65) (cell wall protein A) (antigen A) Hypothetical protein Rv0441c PPE family protein PPE10 Conserved protein Anti-sigma factor RskA (regulator of sigma K) Alternative RNA polymerase sigma factor SigK Possible conserved transmembrane protein Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase) Conserved hypothetical protein Conserved hypothetical protein Probable conserved transmembrane transport protein MmpL4 Probable conserved membrane protein MmpS4 Possible transcriptional regulatory protein PPE family protein PPE11 Conserved hypothetical protein Conserved protein enoyl-CoA hydratase EchA2 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Possible toxin MazF1 Possible antitoxin MazE1 Probable peptidase Probable aldehyde dehydrogenase Conserved hypothetical protein Conserved hydrophobic protein Probable transmembrane protein Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphorase) Probable conserved membrane protein Conserved protein Probable transcriptional regulatory protein Conserved protein Isocitrate lyase Icl (isocitrase) (isocitratase) 3-hydroxybutyryl-CoA dehydrogenase FadB2 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) Possible mycolic acid synthase UmaA Mycolic acid synthase PcaA (cyclopropane synthase) Hypothetical protein Rv0470A Hypothetical protein Rv0471c Probable transcriptional regulatory protein (possibly TetR-family) Possible conserved transmembrane protein Probable transcriptional regulatory protein Iron-regulated heparin binding hemagglutinin HbhA (adhesin) Possible conserved transmembrane protein Possible conserved secreted protein Probable deoxyribose-phosphate aldolase DeoC (phosphodeoxyriboaldolase) (deoxyriboaldolase) Probable conserved membrane protein Possible amidohydrolase Hypothetical protein Rv0481c Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase) Probable conserved lipoprotein LprQ Probable short-chain type oxidoreductase Possible transcriptional regulatory protein Glycosyltransferase MshA Conserved hypothetical protein Probable conserved integral membrane protein Probable phosphoglycerate mutase 1 Gpm1 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) Putative two component sensor histidine kinase SenX3 Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family) Probable oxidoreductase GMC-type Hypothetical protein Rv0492A Conserved protein Probable transcriptional regulatory protein (probably GntR-family) Conserved hypothetical protein Conserved hypothetical protein Probable conserved transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) Conserved protein Conserved hypothetical protein Possible UDP-glucose 4-epimerase GalE2 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase) Conserved protein Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic acid synthase 2) (mycolic acid trans-cyclopropane synthetase) Conserved protein Possible phosphoserine phosphatase SerB1 (PSP) (O-phosphoserine phosphohydrolase) (pspase) Probable conserved membrane protein MmpS2 Probable conserved transmembrane transport protein MmpL2 Conserved hypothetical protein Probable glutamyl-tRNA reductase HemA (GLUTR) Probable porphobilinogen deaminase HemC (PBG) (hydroxymethylbilane synthase) (HMBS) (pre-uroporphyrinogen synthase) Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methylase) (urogen III methylase) (SUMT) (urogen III methylase) (UROM) Probable delta-aminolevulinic acid dehydratase HemB (porphobilinogen synthase) (ALAD) (ALADH) Possible conserved transmembrane protein Possible transmembrane protein Conserved 13E12 repeat family protein Possible anti-anti-sigma factor Possible membrane acyltransferase Possible exported protein Possible conserved membrane protein Possible methyltransferase/methylase (fragment) Possible methyltransferase/methylase (fragment) Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease) Conserved protein Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) Conserved protein Possible thioredoxin protein (thiol-disulfide interchange protein) Possible cytochrome C-type biogenesis protein CcdA Probable conserved transmembrane protein Possible cytochrome C-type biogenesis protein CcsA Conserved protein Conserved protein Possible conserved membrane protein PE-PGRS family protein PE_PGRS6 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA (DHNA-octaprenyltransferase) Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase) Probable integral membrane protein Possible conserved membrane protein Probable dolichyl-phosphate sugar synthase (dolichol-phosphate sugar synthetase) (dolichol-phosphate sugar transferase) (sugar phosphoryldolichol synthase) Conserved hypothetical protein Probable conserved integral membrane protein Possible O-succinylbenzoic acid--CoA ligase MenE (OSB-CoA synthetase) (O-succinylbenzoate-CoA synthase) Conserved protein Possible conserved transmembrane protein Probable low-affinity inorganic phosphate transporter integral membrane protein PitA Conserved protein Possible oxidoreductase Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) Possible toxin VapC3 Possible antitoxin VapB3 Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved protein Probable muconate cycloisomerase MenC (cis,cis-muconate lactonizing enzyme) (MLE) Possible peroxidase BpoC (non-haem peroxidase) Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC) Probable conserved transmembrane protein Mannosyltransferase MgtA Probable ubiquinone/menaquinone biosynthesis methyltransferase MenH (2-heptaprenyl-1,4-naphthoquinone methyltransferase) Possible conserved secreted protein Possible benzoquinone methyltransferase (methylase) Possible oxidoreductase Probable polyprenyl-diphosphate synthase GrcC1 (polyprenyl pyrophosphate synthetase) Probable protease transmembrane protein heat shock protein HtpX Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA1 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase) Probable monooxygenase Conserved protein Probable methyltransferase/methylase Possible cytochrome P450 135B1 Cyp135B1 Conserved protein Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) Conserved protein Hypothetical protein Rv0572c Nicotinic acid phosphoribosyltransferase PncB2 Conserved hypothetical protein Possible oxidoreductase Probable transcriptional regulatory protein (possibly ArsR-family) Conserved protein TB27.3 PE-PGRS family protein PE_PGRS7 Conserved hypothetical protein Conserved protein Possible antitoxin VapB26 Possible toxin VapC26. Contains PIN domain Probable conserved lipoprotein LpqN Possible conserved exported protein Probable conserved integral membrane protein Probable transcriptional regulatory protein Mce2R (GntR-family) Conserved hypothetical integral membrane protein YrbE2A Conserved hypothetical integral membrane protein YrbE2B Mce-family protein Mce2A Mce-family protein Mce2B Mce-family related protein Mce-family protein Mce2C Mce-family protein Mce2D Possible Mce-family lipoprotein LprL (Mce-family lipoprotein Mce2E) Mce-family protein Mce2F Possible toxin VapC4 Possible antitoxin VapB4 Conserved hypothetical protein Possible toxin VapC27. Contains PIN domain Possible antitoxin VapB27 Two component sensor kinase [second part] Two component sensor kinase [first part] Two component DNA binding transcriptional regulatory protein TcrA Possible exported protein Probable conserved lipoprotein LpqO Possible resolvase Possible transposase (fragment) Hypothetical protein Rv0607 Possible antitoxin VapB28 Possible toxin VapC28. Contains PIN domain Conserved hypothetical protein Hypothetical protein Rv0610c Hypothetical protein Rv0611c Conserved hypothetical protein Unknown protein Conserved hypothetical protein Probable integral membrane protein Hypothetical protein Rv0616c Possible antitoxin VapB29 Possible toxin VapC29. Contains PIN domain Probable galactose-1-phosphate uridylyltransferase GalTa [first part] Probable galactose-1-phosphate uridylyltransferase GalTb [second part], partial Probable galactokinase GalK (galactose kinase) Possible membrane protein Possible membrane protein Possible antitoxin VapB30 Possible toxin VapC30. Contains PIN domain Probable conserved transmembrane protein Possible antitoxin VapB5 Possible toxin VapC5 Conserved hypothetical protein Probable exonuclease V (alpha chain) RecD (exodeoxyribonuclease V alpha chain) (exodeoxyribonuclease V polypeptide) Probable exonuclease V (beta chain) RecB (exodeoxyribonuclease V beta chain)(exodeoxyribonuclease V polypeptide) (chi-specific endonuclease) Probable exonuclease V (gamma chain) RecC (exodeoxyribonuclease V gamma chain)(exodeoxyribonuclease V polypeptide) Probable enoyl-CoA hydratase EchA3 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Possible exported protein Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) Unknown protein 50S ribosomal protein L33 RpmG2 (3R)-hydroxyacyl-ACP dehydratase subunit HadA (3R)-hydroxyacyl-ACP dehydratase subunit HadB (3R)-hydroxyacyl-ACP dehydratase subunit HadC Probable preprotein translocase SecE1 Probable transcription antitermination protein NusG 50S ribosomal protein L11 RplK 50S ribosomal protein L1 RplA Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase) Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase) Methoxy mycolic acid synthase 1 MmaA1 (methyl mycolic acid synthase 1) (MMA1) (hydroxy mycolic acid synthase) Probable lipase/esterase LipG Conserved protein Alpha-mannosidase Possible malonyl CoA-acyl carrier protein transacylase FabD2 (MCT) Possible sugar kinase 50S ribosomal protein L10 RplJ 50S ribosomal protein L7/L12 RplL (SA1) Possible transcriptional regulatory protein (probably TetR-family) Probable dioxygenase Possible ribonucleotide-transport ATP-binding protein ABC transporter Mkl Possible toxin VapC6 Possible antitoxin VapB6 Probable conserved integral membrane protein Toxin MazF2 Possible antitoxin MazE2 Possible toxin VapC7 Possible antitoxin VapB7 Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) Possible antitoxin VapB8 Possible toxin VapC8 Possible membrane protein DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) DNA-directed RNA polymerase (beta' chain) RpoC (transcriptase beta' chain) (RNA polymerase beta' subunit) Possible hydrolase Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) Possible conserved lipoprotein LpqP Probable acyl-CoA dehydrogenase FadE8 Possible enoyl-CoA hydratase EchA4 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Conserved hypothetical protein Probable enoyl-CoA hydratase EchA5 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable conserved transmembrane transport protein MmpL5 Possible conserved membrane protein MmpS5 Conserved protein Conserved threonine rich protein Probable conserved transmembrane protein Probable transcriptional regulatory protein (possibly TetR-family) 30S ribosomal protein S12 RpsL 30S ribosomal protein S7 RpsG Probable elongation factor G FusA1 (EF-G) Probable iron-regulated elongation factor TU Tuf (EF-TU) Probable membrane protein Probable short-chain type dehydrogenase/reductase Putative ferredoxin reductase Hypothetical protein Rv0689c Conserved hypothetical protein Probable transcriptional regulatory protein Mycofactocin precursor protein Conserved hypothetical protein Probable coenzyme PQQ synthesis protein E PqqE (coenzyme PQQ synthesis protein III) Possible L-lactate dehydrogenase (cytochrome) LldD1 Conserved hypothetical protein Probable membrane sugar transferase Probable dehydrogenase Conserved hypothetical protein Hypothetical protein Rv0699 30S ribosomal protein S10 RpsJ (transcription antitermination factor NusE) 50S ribosomal protein L3 RplC 50S ribosomal protein L4 RplD 50S ribosomal protein L23 RplW 50S ribosomal protein L2 RplB 30S ribosomal protein S19 RpsS 50S ribosomal protein L22 RplV 30S ribosomal protein S3 RpsC 50S ribosomal protein L16 RplP 50S ribosomal protein L29 RpmC 30S ribosomal protein S17 RpsQ Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) Conserved protein Probable conserved transmembrane protein 50S ribosomal protein L14 RplN 50S ribosomal protein L24 RplX 50S ribosomal protein L5 RplE 30S ribosomal protein S14 RpsN1 30S ribosomal protein S8 RpsH 50S ribosomal protein L6 RplF 50S ribosomal protein L18 RplR 30S ribosomal protein S5 RpsE 50S ribosomal protein L30 RpmD 50S ribosomal protein L15 RplO Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase) Conserved hypothetical protein, partial Conserved hypothetical protein Possible S-adenosylmethionine-dependent methyltransferase Possible L-fuculose phosphate aldolase FucA (L-fuculose-1-phosphate aldolase) Possible D-3-phosphoglycerate dehydrogenase SerA2 (phosphoglycerate dehydrogenase) (PGDH) Possible D-xylulose kinase XylB (xylulokinase) (xylulose kinase) GCN5-related N-acetyltransferase Possible S-adenosylmethionine-dependent methyltransferase Probable preprotein translocase SecY Adenylate kinase Adk (ATP-AMP transphosphorylase) Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) Probable alternative RNA polymerase sigma factor SigL Anti-sigma factor RslA Possible transcriptional regulatory protein Conserved protein Conserved hypothetical protein Conserved hypothetical protein Probable transposase (fragment) PE-PGRS family protein PE_PGRS8 Hypothetical protein Rv0743c Possible transcriptional regulatory protein Conserved hypothetical protein PE-PGRS family protein PE_PGRS9 PE-PGRS family protein PE_PGRS10 Possible antitoxin VapB31 Possible toxin VapC31. Contains PIN domain Hypothetical protein (fragment) Conserved hypothetical protein Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh) Probable acyl-CoA dehydrogenase FadE9 Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) PE-PGRS family protein PE_PGRS11 PPE family protein PPE12 Putative transposase (fragment) Unknown protein Possible two component system response transcriptional positive regulator PhoP Possible two component system response sensor kinase membrane associated PhoR Conserved hypothetical protein Conserved protein Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB Conserved hypothetical protein Possible ferredoxin Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) Probable oxidoreductase Probable cytochrome P450 123 Cyp123 Conserved hypothetical protein Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) Probable dehydrogenase/reductase Probable dehydrogenase/reductase Possible 4-carboxymuconolactone decarboxylase (CMD) Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase) Probable bifunctional acylase GgtA: cephalosporin acylase (GL-7ACA acylase) + gamma-glutamyltranspeptidase (GGT) Probable conserved exported protein Conserved hypothetical protein Conserved hypothetical protein Probable adenylosuccinate lyase PurB (adenylosuccinase) (ASL) (ASASE) Possible cytochrome P450 126 Cyp126 Possible conserved transmembrane protein Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC (SAICAR synthetase) Probable protease II PtrBa [first part] (oligopeptidase B) Probable protease II PtrBb [second part] (oligopeptidase B) Possible multidrug resistance integral membrane efflux protein EmrB Conserved hypothetical protein Conserved protein Conserved protein Unknown protein Conserved protein Probable phosphoribosylformylglycinamidine synthase I PURG (FGAM synthase I) Hypothetical protein Rv0789c Hypothetical protein Rv0790c Conserved protein Probable transcriptional regulatory protein (probably GntR-family) Possible monooxygenase Probable oxidoreductase Putative transposase for insertion sequence element IS6110 (fragment) Putative transposase for insertion sequence element IS6110, partial Putative transposase for insertion sequence element IS1547 29 KDa antigen CFP29 Conserved protein Probable aminopeptidase PepC Conserved protein Possible succinyltransferase in the GCN5-related N-acetyltransferase family Phosphoribosylformylglycinamidine synthase II PurL (FGAM synthase II) Conserved hypothetical protein Class III cyclic nucleotide phosphodiesterase (cNMP PDE) Possible UDP-glucose-4-epimerase CpsY (galactowaldenase) (UDP-galactose-4-epimerase) (uridine diphosphate galactose-4-epimerase) (uridine diphospho-galactose-4-epimerase) Conserved hypothetical protein Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) Conserved hypothetical protein Conserved protein Probable amino acid aminotransferase Conserved protein Conserved protein SseC2 Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) Probable thioredoxin ThiX Probable conserved exported protein Transcriptional regulatory protein GCN5-related N-acetyltransferase, MshD Probable phosphate-transport ATP-binding protein ABC transporter PhoT Probable phosphate-transport system transcriptional regulatory protein PhoY2 Conserved protein Possible transcriptional regulatory protein Probable acyl-[acyl-carrier protein] desaturase DesA1 (acyl-[ACP] desaturase) (stearoyl-ACP desaturase) (protein Des) Conserved protein Conserved hypothetical protein Metal sensor transcriptional regulator KmtR (ArsR-SmtB family) Possible deaminase Possible transposase (fragment) Possible S-adenosylmethionine-dependent methyltransferase Conserved protein PE-PGRS family protein PE_PGRS12 PE-PGRS family protein PE_PGRS13 PE-PGRS family protein PE_PGRS14 Possible lipoprotein LpqQ Hypothetical protein Rv0836c Hypothetical protein Rv0837c Probable conserved lipoprotein LpqR Conserved hypothetical protein Probable proline iminopeptidase Pip (prolyl aminopeptidase) (pap) Probable conserved transmembrane protein Probable conserved integral membrane protein Probable dehydrogenase Possible nitrate/nitrite response transcriptional regulatory protein NarL Possible two component sensor kinase Probable oxidase Probable lipoprotein LpqS Possible cysteine synthase a CysK2 (O-acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSASE) Probable conserved integral membrane transport protein Putative transposase (fragment) Probable short-chain type dehydrogenase/reductase Possible fatty-acid-CoA ligase FadD16 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable pyruvate or indole-3-pyruvate decarboxylase Pdc Conserved protein Probable fatty-acid-CoA racemase Far Conserved hypothetical protein Conserved hypothetical protein Probable N-succinyldiaminopimelate aminotransferase DapC (DAP-at) Possible acyl-CoA thiolase FadA Probable fatty oxidation protein FadB DNA helicase Ercc3 Conserved protein Conserved hypothetical protein Probable molybdenum cofactor biosynthesis protein C 2 MoaC2 Probable molybdopterin biosynthesis Mog protein Probable molybdenum cofactor biosynthesis protein E2 MoaE2 (molybdopterin converting factor large subunit) (molybdopterin [MPT] converting factor, subunit 2) Possible resuscitation-promoting factor RpfA Probable molybdenum cofactor biosynthesis protein D 2 MoaD2 (molybdopterin converting factor small subunit) (molybdopterin [MPT] converting factor, subunit 1) Probable molybdenum cofactor biosynthesis protein A2 MoaA2 Possible conserved integral membrane protein Probable cold shock-like protein B CspB PE-PGRS family protein PE_PGRS15 Probable acyl-CoA dehydrogenase FadE10 Conserved hypothetical protein Possible conserved exported protein Possible conserved transmembrane protein Conserved hypothetical protein PPE family protein PPE13 Possible conserved transmembrane protein Possible transcriptional regulatory protein (possibly MarR-family) Possible rRNA methyltransferase (rRNA methylase) Probable transmembrane protein Conserved hypothetical protein Possible phosphoserine aminotransferase SerC (PSAT) Conserved hypothetical protein Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) Conserved hypothetical protein Probable exported protein Probable citrate synthase II CitA Probable transcriptional regulatory protein (probably LuxR-family) Possible transcriptional regulatory protein Probable monooxygenase Possible S-adenosylmethionine-dependent methyltransferase Possible transcriptional regulatory protein (possibly LuxR-family) Possible triacylglycerol synthase (diacylglycerol acyltransferase) Probable citrate synthase I GltA2 Probable oxidoreductase Conserved hypothetical protein Outer membrane protein A OmpA Possible membrane protein Possible conserved exported or membrane protein Two component sensor histidine kinase PrrB Two component response transcriptional regulatory protein PrrA Putative acetyl-coenzyme A carboxylase carboxyl transferase (subunit beta) AccD3 (accase beta chain) Possible enoyl-CoA hydratase EchA6 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Conserved protein Conserved protein Probable metal cation transporter ATPase P-type CtpE Conserved hypothetical protein Conserved hypothetical protein Conserved protein Probable conserved transmembrane protein Possible dioxygenase Possible lipid carrier protein or keto acyl-CoA thiolase PPE family protein PPE14 PE family protein PE7 Possible glycine betaine transport integral membrane protein BetP Conserved protein GCN5-related N-acetyltransferase Probable transposase Possible resolvase Possible transposase Conserved hypothetical protein Divalent cation-transport integral membrane protein MntH (BRAMP) (MRAMP) Conserved protein Conserved hypothetical protein Probable short-chain type dehydrogenase/reductase Periplasmic phosphate-binding lipoprotein PstS3 (PBP-3) (PstS3) (PHOS1) Phosphate-transport integral membrane ABC transporter PstC2 Probable phosphate-transport integral membrane ABC transporter PstA1 Transmembrane serine/threonine-protein kinase D PknD (protein kinase D) (STPK D) Periplasmic phosphate-binding lipoprotein PstS2 (PBP-2) (PstS2) Phosphate-transport ATP-binding protein ABC transporter PstB Periplasmic phosphate-binding lipoprotein PstS1 (PBP-1) (PstS1) Phosphate-transport integral membrane ABC transporter PstC1 Phosphate-transport integral membrane ABC transporter PstA2 DNA end-binding protein, Mku ATP dependent DNA ligase LigD (ATP dependent polydeoxyribonucleotide synthase) (thermostable DNA ligase) (ATP dependent polynucleotide ligase) (sealase) (DNA repair enzyme) (DNA joinase) Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase Possible oxidoreductase Conserved hypothetical protein Hypothetical protein Rv0942 Probable monooxygenase Possible formamidopyrimidine-DNA glycosylase (FAPY-DNA glycosylase) Probable short-chain type dehydrogenase/reductase Probable glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (phosphohexose isomerase) (phi) Chorismate mutase Probable ATP-dependent DNA helicase II UvrD1 Conserved hypothetical protein Probable succinyl-CoA synthetase (beta chain) SucC (SCS-beta) Probable succinyl-CoA synthetase (alpha chain) SucD (SCS-alpha) Possible oxidoreductase Probable conserved transmembrane protein Probable conserved integral membrane protein Probable 5'-phosphoribosylglycinamide formyltransferase PurN (GART) (gar transformylase) (5'-phosphoribosylglycinamide transformylase) Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC) Possible magnesium chelatase Conserved hypothetical protein Possible antitoxin VapB9 Possible toxin VapC9 Probable integral membrane protein Possible lipoprotein LprP Conserved hypothetical protein Hypothetical protein Rv0964c Conserved hypothetical protein Conserved protein Copper-sensitive operon repressor CsoR Conserved protein Probable metal cation transporter P-type ATPase CtpV Probable conserved integral membrane protein Probable enoyl-CoA hydratase EchA7 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Acyl-CoA dehydrogenase FadE12 Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrier protein (BCCP) Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD2 Probable acyl-CoA dehydrogenase FadE13 Conserved hypothetical protein PE-PGRS family protein PE_PGRS16 PE-PGRS family protein PE_PGRS17 Hypothetical protein Rv0979c 50S ribosomal protein L32 RpmF PE-PGRS family protein PE_PGRS18 Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein) Two component sensor kinase MprB Probable serine protease PepD (serine proteinase) (MTB32B) Possible pterin-4-alpha-carbinolamine dehydratase MoaB2 (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin-4-a-carbinolamine dehydratase) (phenylalanine hydroxylase-stimulating protein) (PHS) (pterin carbinolamine dehydratase) (PCD) Possible large-conductance ion mechanosensitive channel MscL Probable adhesion component transport ATP-binding protein ABC transporter Probable adhesion component transport transmembrane protein ABC transporter Possible conserved exported protein Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) Hypothetical protein Rv0990c Conserved serine rich protein Conserved hypothetical protein UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase) (UDPGP) (alpha-D-glucosyl-1-phosphate uridylyltransferase) (uridine diphosphoglucose pyrophosphorylase) Probable molybdopterin biosynthesis protein MoeA1 Ribosomal-protein-alanine acetyltransferase RimJ (acetylating enzyme for N-terminal of ribosomal protein S5) Probable conserved transmembrane protein Hypothetical protein Rv0997 Conserved hypothetical protein Unknown protein Conserved hypothetical protein Probable arginine deiminase ArcA (adi) (ad) (arginine dihydrolase) Conserved membrane protein Conserved protein Probable membrane protein Probable para-aminobenzoate synthase component I PABD Unknown protein Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) Probable deoxyribonuclease TatD (YJJV protein) Probable resuscitation-promoting factor RpfB Probable dimethyladenosine transferase KsgA (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (high level kasugamycin resistance protein KsgA) (kasugamycin dimethyltransferase) Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) Hypothetical protein Rv1012 Putative polyketide synthase Pks16 Probable peptidyl-tRNA hydrolase Pth 50S ribosomal protein L25 RplY Probable conserved lipoprotein LpqT Probable ribose-phosphate pyrophosphokinase PrsA (phosphoribosyl pyrophosphate synthetase) (PRPP synthetase) Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Probable transcriptional regulatory protein (probably TetR-family) Probable transcription-repair coupling factor Mfd (TRCF) Conserved protein Probable conserved lipoprotein LpqU Probable enolase Eno Possible conserved membrane protein Conserved protein Conserved protein Probable transcriptional regulatory protein KdpE Probable sensor protein KdpD Probable membrane protein KdpF Probable potassium-transporting ATPase a chain KdpA (potassium-translocating ATPase a chain) (ATP phosphohydrolase [potassium-transporting] a chain) (potassium binding and translocating subunit A) Probable potassium-transporting P-type ATPase B chain KdpB (potassium-translocating ATPase B chain) (ATP phosphohydrolase [potassium-transporting] B chain) (potassium binding and translocating subunit B) Probable potassium-transporting ATPase C chain KdpC (potassium-translocating ATPase C chain) (ATP phosphohydrolase [potassium-transporting] C chain) (potassium binding and translocating subunit C) Two component sensor histidine kinase TrcS Two component transcriptional regulator TrcR Probable transposase (fragment) Probable transposase (fragment) Probable IS1560 transposase (fragment) Putative ESAT-6 like protein EsxI (ESAT-6 like protein 1) ESAT-6 like protein EsxJ (ESAT-6 like protein 2) PPE family protein PPE15 PE family protein PE8 Probable is like-2 transposase Probable is like-2 transposase Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv1045 Hypothetical protein Rv1046c Probable transposase Hypothetical protein Rv1048c Probable transcriptional repressor protein Probable oxidoreductase Conserved hypothetical protein Hypothetical protein Rv1052 Hypothetical protein Rv1053c Probable integrase (fragment) Possible integrase (fragment) Conserved protein Conserved hypothetical protein Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved protein Unknown protein Conserved protein Conserved hypothetical protein Conserved hypothetical protein Possible lipoprotein LpqV Conserved hypothetical protein Conserved hypothetical protein PE-PGRS family protein PE_PGRS19 PE-PGRS family protein PE_PGRS20 Conserved protein Probable enoyl-CoA hydratase EchA8 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Possible enoyl-CoA hydratase EchA9 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable conserved transmembrane protein Conserved hypothetical protein Probable beta-ketoacyl CoA thiolase FadA3 Conserved exported protein Possible lipase LipU Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) Probable proline-rich antigen homolog Pra Cystathionine gamma-synthase MetB (CGS) (O-succinylhomoserine [thiol]-lyase) Probable transcription elongation factor GreA (transcript cleavage factor GreA) Probable conserved membrane protein Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) Conserved hypothetical protein Conserved protein Possible hemolysin-like protein Short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP synthase) (Z-farnesyl diphosphate synthase) (Z-FPP synthetase) (Z-farnesyl diphosphate synthetase) (geranyltranstransferase) (farnesyl pyrophosphate synthetase) PE-PGRS family protein PE_PGRS21 Conserved hypothetical protein PE family protein PE9 PE family protein PE10, partial Probable cellulase CelA2a (endo-1,4-beta-glucanase) (endoglucanase) (carboxymethyl cellulase) Probable cellulase CelA2b (endo-1,4-beta-glucanase) (endoglucanase) (carboxymethyl cellulase) PE-PGRS family protein PE_PGRS22 Probable pantothenate kinase CoaA (pantothenic acid kinase) Serine hydroxymethyltransferase 1 GlyA1 Possible acyl-[acyl-carrier protein] desaturase DesA2 (acyl-[ACP] desaturase) (stearoyl-ACP desaturase) Probable PHOH-like protein PhoH2 (phosphate starvation-inducible protein PSIH) Possible glycosyl hydrolase Probable membrane glycine and proline rich protein Probable fumarase Fum (fumarate hydratase) Fructose 1,6-bisphosphatase GlpX Conserved protein Conserved membrane protein Toxin MazF3 Possible antitoxin MazE3 Possible para-nitrobenzyl esterase (fragment) Possible para-nitrobenzyl esterase (fragment) 3-beta-hydroxysteroid dehydrogenase Probable exodeoxyribonuclease VII (small subunit) XseB (exonuclease VII small subunit) Probable exodeoxyribonuclease VII (large subunit) XseA (exonuclease VII large subunit) Conserved protein Probable LYTB-related protein LytB2 Conserved hypothetical protein Probable GTP binding protein Possible antitoxin VapB32 Possible toxin VapC32. Contains PIN domain Possible exported protein Hypothetical protein Rv1116 Conserved hypothetical protein (fragment) Conserved protein Conserved protein Hypothetical protein Rv1119c Conserved hypothetical protein Probable glucose-6-phosphate 1-dehydrogenase Zwf1 (G6PD) Probable 6-phosphogluconate dehydrogenase,decarboxylating Gnd2 Possible peroxidase BpoB (non-haem peroxidase) Probable epoxide hydrolase EphC (epoxide hydratase) Conserved hypothetical protein Conserved protein Probable pyruvate, phosphate dikinase PpdK Conserved hypothetical protein Probable transcriptional regulator protein Possible methylcitrate dehydratase PrpD Probable methylcitrate synthase PrpC Conserved membrane protein Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) Hypothetical protein Rv1134 PPE family protein PPE16 Possible acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase) Possible enoyl-CoA hydratase Hypothetical protein Rv1137c Possible oxidoreductase Conserved hypothetical membrane protein Probable integral membrane protein Probable enoyl-CoA hydratase EchA11 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable enoyl-CoA hydratase EchA10 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) Probable short-chain type dehydrogenase/reductase Probable conserved transmembrane transport protein MmpL13a Probable conserved transmembrane transport protein MmpL13b Conserved protein Conserved hypothetical protein Possible transposase Transcriptional regulatory protein Probable transcriptional regulatory protein Probable O-methyltransferase Omt Hypothetical protein Rv1154c Possible pyridoxamine 5'-phosphate oxidase (PNP/PMP oxidase) (pyridoxinephosphate oxidase) (PNPOX) (pyridoxine 5'-phosphate oxidase) Conserved protein Conserved ala-, pro-rich protein Conserved hypothetical ala-, pro-rich protein Mannosyltransferase PimE Unknown protein Probable mutator protein MutT2 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) Respiratory nitrate reductase (alpha chain) NarG Probable respiratory nitrate reductase (beta chain) NarH Probable respiratory nitrate reductase (delta chain) NarJ Probable respiratory nitrate reductase (gamma chain) NarI Possible GTP-binding translation elongation factor TypA (tyrosine phosphorylated protein A) (GTP-binding protein) Probable conserved lipoprotein LpqW Probable transcriptional regulatory protein PPE family protein PPE17 PE family protein. Possible lipase LipX N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) Conserved hypothetical protein PE family protein PE12 Probable F420 biosynthesis protein FbiC Low molecular weight T-cell antigen TB8.4 Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) Conserved hypothetical protein Probable ferredoxin FdxC Probable aminotransferase Unknown protein Probable polyketide beta-ketoacyl synthase Pks3 Probable polyketide beta-ketoacyl synthase Pks4 Probable conserved polyketide synthase associated protein PapA3 Probable conserved transmembrane transport protein MmpL10 Possible exported protein Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Conserved protein Probable pyrroline-5-carboxylate dehydrogenase RocA Probable proline dehydrogenase Possible alternative RNA polymerase sigma factor SigI Conserved hypothetical protein Conserved protein Unknown protein Probable fatty-acid-CoA ligase FadD36 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved protein PE family protein PE13 PPE family protein PPE18 ESAT-6 like protein EsxK (ESAT-6 like protein 3) Putative ESAT-6 like protein EsxL (ESAT-6 like protein 4) Possible transposase Probable conserved integral membrane transport protein Tetrahydrodipicolinate N-succinyltransferase DapD Probable succinyl-diaminopimelate desuccinylase DapE Hypothetical protein Rv1203c Conserved hypothetical protein Conserved hypothetical protein Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Dihydropteroate synthase 2 FolP2 (DHPS 2) (dihydropteroate pyrophosphorylase 2) Probable glucosyl-3-phosphoglycerate synthase GpgS Conserved protein Probable DNA-3-methyladenine glycosylase I TagA (tag I) (3-methyladenine-DNA glycosylase I, constitutive) (DNA-3-methyladenine glycosidase I) Conserved protein Putative glycosyl transferase GlgA Glucose-1-phosphate adenylyltransferase GlgC (ADP-glucose synthase) (ADP-glucose pyrophosphorylase) PE family protein PE14 Conserved protein Probable conserved integral membrane protein Probable tetronasin-transport integral membrane protein ABC transporter Probable tetronasin-transport ATP-binding protein ABC transporter Probable transcriptional regulatory protein Probable methyltransferase Alternative RNA polymerase sigma factor SigE Anti-sigma factor RseA Probable serine protease HtrA (DEGP protein) Probable protein TatB Conserved hypothetical protein Probable transmembrane protein Probable transmembrane protein Probable lipoprotein LpqX Probable Mrp-related protein Mrp Possible membrane protein Probable membrane protein Conserved protein Conserved hypothetical membrane protein Probable transmembrane protein Probable sugar-binding lipoprotein LpqY Probable sugar-transport integral membrane protein ABC transporter SugA Probable sugar-transport integral membrane protein ABC transporter SugB Probable sugar-transport ATP-binding protein ABC transporter SugC Possible magnesium and cobalt transport transmembrane protein CorA Probable malate dehydrogenase Mdh Possible antitoxin VapB33 Possible toxin VapC33. Contains PIN domain PE-PGRS family protein PE_PGRS23 Probable lipoprotein LpqZ Probable short-chain type dehydrogenase/reductase Toxin RelE Antitoxin RelB Multifunctional alpha-ketoglutarate metabolic enzyme Possible membrane protein Probable drug-transport integral membrane protein Conserved hypothetical protein Probable lipoprotein LprE Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) Probable acyltransferase Probable transcriptional regulatory protein Probable cytochrome P450 130 Cyp130 Probable oxidoreductase Probable conserved integral membrane transport protein Probable uracil DNA glycosylase, UdgB Probable oxidoreductase Conserved protein Hypothetical hit-like protein Probable amidase AmiB2 (aminohydrolase) Adenylyl cyclase (ATP pyrophosphate-lyase) (adenylate cyclase) Unknown protein Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H) Probable transcriptional regulatory protein EmbR Hypothetical protein Rv1268c Conserved probable secreted protein Possible lipoprotein LprA Conserved hypothetical secreted protein Probable drugs-transport transmembrane ATP-binding protein ABC transporter Probable drugs-transport transmembrane ATP-binding protein ABC transporter Possible lipoprotein LprB Possible lipoprotein LprC Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv1278 Probable dehydrogenase FAD flavoprotein GMC oxidoreductase Probable periplasmic oligopeptide-binding lipoprotein OppA Probable oligopeptide-transport ATP-binding protein ABC transporter OppD Probable oligopeptide-transport integral membrane protein ABC transporter OppC Probable oligopeptide-transport integral membrane protein ABC transporter OppB Beta-carbonic anhydrase Probable sulfate adenylyltransferase subunit 2 CysD Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + adenylylsulfate kinase Conserved hypothetical protein Conserved protein Unknown protein Conserved protein Hypothetical protein Rv1290A Conserved hypothetical secreted protein Probable arginyl-tRNA synthetase ArgS (ARGRS) (arginine--tRNA ligase) Diaminopimelate decarboxylase LysA (DAP decarboxylase) Probable homoserine dehydrogenase ThrA Threonine synthase ThrC (ts) Probable homoserine kinase ThrB Probable transcription termination factor Rho homolog 50S ribosomal protein L31 RpmE Probable peptide chain release factor 1 PrfA (RF-1) Probable HemK protein homolog HemK Conserved protein Probable undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe (UDP-GlcNAc transferase) Conserved hypothetical transmembrane protein Probable ATP synthase a chain AtpB (protein 6) Probable ATP synthase C chain AtpE (lipid-binding protein) (dicyclohexylcarbodiimide-binding protein) Probable ATP synthase B chain AtpF Probable ATP synthase delta chain AtpH Probable ATP synthase alpha chain AtpA Probable ATP synthase gamma chain AtpG Probable ATP synthase beta chain AtpD Probable ATP synthase epsilon chain AtpC Conserved hypothetical secreted protein Possible transposase Conserved protein Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA Methylated-DNA--protein-cysteine methyltransferase Ogt (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) Probable bifunctional regulatory protein and DNA repair enzyme AlkA (regulatory protein of adaptative response) (methylphosphotriester-DNA--protein-cysteine S-methyltransferase) Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) Conserved hypothetical protein Conserved hypothetical protein Conserved protein Probable acetyl-CoA acetyltransferase FadA4 (acetoacetyl-CoA thiolase) Possible thioredoxin PE-PGRS family protein PE_PGRS24 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) Probable glucanase GlgE Probable glycogen phosphorylase GlgP Probable ATP-dependent helicase DinG Nicotinic acid phosphoribosyltransferase PncB1 Conserved hypothetical protein Probable transcriptional regulatory protein Probable hydrolase Possible hydrolase Sulfur carrier protein CysO Cysteine synthase B CysM (CSASE B) (O-phosphoserine sulfhydrylase B) (O-phosphoserine (thiol)-lyase B) Probable integral membrane protein Probable glutamate racemase MurI Conserved protein Probable ribonuclease RphA (RNase PH) (tRNA nucleotidyltransferase) Conserved protein Conserved membrane protein Probable conserved lipoprotein LprD Acyl carrier protein (ACP) MbtL Probable fatty acyl-AMP ligase MbtM Acyl-CoA dehydrogenase MbtN Lysine N-acetyltransferase MbtK Iron-regulated transporter IrtA Iron-regulated transporter IrtB Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) Hypothetical protein Rv1351 Conserved protein Probable transcriptional regulatory protein Conserved hypothetical protein Possible molybdopterin biosynthesis protein MoeY Hypothetical protein Rv1356c Conserved hypothetical protein Probable transcriptional regulatory protein Probable transcriptional regulatory protein Probable oxidoreductase PPE family protein PPE19 Possible membrane protein Possible membrane protein Possible sigma factor regulatory protein Anti-anti-sigma factor RsfA (anti-sigma factor antagonist) (regulator of sigma F A) Hypothetical protein Rv1366 Conserved protein Conserved protein Probable conserved lipoprotein LprF Probable transposase, partial Putative transposase for insertion sequence element IS6110 (fragment) Probable conserved membrane protein Conserved hypothetical protein Glycolipid sulfotransferase Hypothetical protein Rv1374c Conserved hypothetical protein Conserved hypothetical protein Putative transferase Conserved hypothetical protein Probable pyrimidine operon regulatory protein PyrR Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase) Probable dihydroorotase PyrC (DHOase) Probable export or membrane protein Probable carbamoyl-phosphate synthase small chain CarA (carbamoyl-phosphate synthetase glutamine chain) Probable carbamoyl-phosphate synthase large chain CarB (carbamoyl-phosphate synthetase ammonia chain) Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (ompdecase) PE family protein PE15 PPE family protein PPE20 Putative integration host factor MihF Probable guanylate kinase Gmk Probable DNA-directed RNA polymerase (omega chain) RpoZ (transcriptase omega chain) (RNA polymerase omega subunit) Probable DNA/pantothenate metabolism flavoprotein homolog Dfp Probable S-adenosylmethionine synthetase MetK (mat) (AdoMet synthetase) (methionine adenosyltransferase) Probable monoxygenase Probable cytochrome P450 132 Cyp132 Transcriptional regulatory protein PE-PGRS family protein PE_PGRS25 Possible toxin VapC10 Possible antitoxin VapB10 Probable non lipolytic carboxylesterase NlhH Probable lipase LipH Possible membrane protein Putative primosomal protein N' PriA (replication factor Y) Putative methyltransferase Probable transcriptional regulatory protein Putative methyltransferase Probable methionyl-tRNA formyltransferase Fmt Probable Fmu protein (sun protein) Probable ribulose-phosphate 3-epimerase Rpe (PPE) (R5P3E) (pentose-5-phosphate 3-epimerase) Probable bifunctional riboflavin biosynthesis protein RibG : diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase) Aminoglycosides/tetracycline-transport integral membrane protein Conserved lipoprotein LprG Probable riboflavin synthase alpha chain RibC (RibE) Conserved hypothetical protein Conserved hypothetical protein Probable riboflavin biosynthesis protein RibA2 : GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) Probable riboflavin synthase beta chain RibH (6,7-dimethyl-8-ribityllumazine synthase) (DMRL synthase) (lumazine synthase) Possible conserved membrane protein Probable lipoprotein LprH Unknown protein Probable excinuclease ABC (subunit C-nuclease) UvrC Conserved protein Conserved hypothetical protein Probable transcriptional regulatory protein WhiA Possible membrane protein Possible triacylglycerol synthase (diacylglycerol acyltransferase) Probable esterase LipO Possible long-chain-fatty-acid--CoA ligase FadD12 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Conserved hypothetical protein Conserved protein PE family protein PE16 Conserved membrane protein Probable dehydrogenase Possible conserved exported protein Hypothetical protein Rv1434 Probable conserved proline, glycine, valine-rich secreted protein Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) Probable phosphoglycerate kinase Pgk Probable triosephosphate isomerase Tpi (TIM) Unknown protein Probable protein-export membrane protein (translocase subunit) SecG PE-PGRS family protein PE_PGRS26 Probable biotin sulfoxide reductase BisC (BDS reductase) (BSO reductase) Unknown protein Unknown protein Probable 6-phosphogluconolactonase DevB (6PGL) Putative OXPP cycle protein OpcA Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) Probable transaldolase Tal Transketolase Tkt (TK) PE-PGRS family protein PE_PGRS27 Probable cytochrome C oxidase assembly factor CtaB PE-PGRS family protein PE_PGRS28 Possible transcriptional activator protein Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) Conserved protein Probable unidentified antibiotic-transport integral membrane ABC transporter Probable unidentified antibiotic-transport integral membrane ABC transporter Probable unidentified antibiotic-transport ATP-binding protein ABC transporter Possible conserved integral membrane protein Probable transcriptional regulatory protein Conserved protein Conserved hypothetical protein Probable conserved ATP-binding protein ABC transporter Probable cysteine desulfurase Csd Possible nitrogen fixation related protein Conserved protein Probable acyl-CoA dehydrogenase FadE15 PE-PGRS family protein PE_PGRS29 Probable cation transporter P-type ATPase D CtpD Probable thioredoxin TrxA Probable thioredoxin TrxB1 Possible enoyl-CoA hydratase EchA12 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable macrolide-transport ATP-binding protein ABC transporter Possible transcriptional regulatory protein Probable transcriptional regulatory protein Probable iron-regulated aconitate hydratase Acn (citrate hydro-lyase) (aconitase) Possible membrane protein Peptidoglycan hydrolase Possible invasion protein Probable transcriptional regulatory protein MoxR1 Conserved protein Probable membrane protein Conserved hypothetical protein 3-oxoacyl-[acyl-carrier protein] reductase FabG1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein) NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) Conserved hypothetical protein Conserved membrane protein Possible exported conserved protein Conserved protein Conserved protein Probable membrane protein Conserved membrane protein Probable methylmalonyl-CoA mutase small subunit MutA (MCM) Probable methylmalonyl-CoA mutase large subunit MutB (MCM) Possible antitoxin MazE4 Possible toxin MazF4 Possible transport system kinase Probable esterase LipL Probable methyltransferase Conserved protein Hypothetical protein Rv1499 Probable glycosyltransferase Conserved hypothetical protein Hypothetical protein Rv1502 Conserved hypothetical protein, partial Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv1506c Conserved protein Hypothetical protein Rv1507A Probable membrane protein Conserved hypothetical protein Hypothetical protein Rv1509 Conserved probable membrane protein GDP-D-mannose dehydratase GmdA (GDP-mannose 4,6 dehydratase) (GMD) Probable nucleotide-sugar epimerase EpiA Conserved protein Conserved hypothetical protein Conserved hypothetical protein Probable sugar transferase Conserved hypothetical transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Probable sugar transferase Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Probable conserved transmembrane transport protein MmpL12 Probable methyltransferase Probable glycosyltransferase Possible rhamnosyl transferase WbbL2 Probable glycosyltransferase Probable polyketide synthase Pks5 Probable conserved polyketide synthase associated protein PapA4 Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Probable alcohol dehydrogenase Adh Conserved protein Conserved hypothetical protein Conserved protein Probable transcriptional regulator Unknown protein Isoleucyl-tRNA synthetase IleS Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) Probable L-aparaginase AnsA Probable lipoprotein signal peptidase LspA Conserved hypothetical protein member of yabO/yceC/yfiI family Possible lipoprotein LprI Hemoglobin GlbN Possible fatty acyl-CoA reductase Possible ketoacyl reductase Hypothetical protein Rv1545 Conserved protein Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) PPE family protein PPE21 Possible fatty-acid-CoA ligase FadD11.1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable fatty-acid-CoA ligase FadD11 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Possible acyltransferase PlsB1 Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase) Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase) Probable fumarate reductase [membrane anchor subunit] FrdC (fumarate dehydrogenase) (fumaric hydrogenase) Probable fumarate reductase [membrane anchor subunit] FrdD (fumarate dehydrogenase) (fumaric hydrogenase) Possible regulatory protein Probable conserved transmembrane transport protein MmpL6 Conserved protein Probable threonine dehydratase IlvA Possible antitoxin VapB11 Possible toxin VapC11 Maltooligosyltrehalose trehalohydrolase TreZ Maltooligosyltrehalose synthase TreY Probable maltooligosyltrehalose synthase TreX Conserved hypothetical membrane protein Possible Inv protein Probable hypothetical membrane protein Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase) Dethiobiotin synthetase BioD Conserved protein Conserved hypothetical protein Probable PhiRv1 phage protein Probable PhiRv1 phage related protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Probable PhiRv1 phage protein Possible PhiRv1 phage protein Possible phage PhiRv1 protein Probable PhiRv1 integrase Partial REP13E12 repeat protein Partial REP13E12 repeat protein Probable biotin synthetase BioB Conserved hypothetical protein Probable transmembrane protein Conserved hypothetical protein Conserved protein Probable quinolinate synthetase NadA Probable L-aspartate oxidase NadB Probable nicotinate-nucleotide pyrophosphatase NadC Hypothetical protein Rv1597 Conserved protein Probable histidinol dehydrogenase HisD (HDH) Probable histidinol-phosphate aminotransferase HisC1 Probable imidazole glycerol-phosphate dehydratase HisB Probable amidotransferase HisH Probable phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA Probable inositol-monophosphatase ImpA (imp) Probable cyclase HisF Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI Probable ionic transporter integral membrane protein ChaA Probable peroxidoxin BcpB Anthranilate synthase component I TrpE (glutamine amidotransferase) Possible conserved membrane protein Probable indole-3-glycerol phosphate synthase TrpC Tryptophan synthase, beta subunit TrpB Probable tryptophan synthase, alpha subunit TrpA Possible prolipoprotein diacylglyceryl transferases Lgt Probable membrane protein Conserved membrane protein Probable pyruvate kinase PykA Probable acyl-CoA thioesterase II TesB1 Conserved membrane protein Probable 'component linked with the assembly of cytochrome' transport transmembrane ATP-binding protein ABC transporter CydC Probable 'component linked with the assembly of cytochrome' transport transmembrane ATP-binding protein ABC transporter CydD Probable integral membrane cytochrome D ubiquinol oxidase (subunit II) CydB (cytochrome BD-I oxidase subunit II) Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) CydA (cytochrome BD-I oxidase subunit I) Probable conserved membrane protein Membrane-anchored adenylyl cyclase Cya (ATP pyrophosphate-lyase) (adenylate cyclase) Probable two-component system transcriptional regulator Probable nonspecific lipid-transfer protein Conserved protein Probable DNA polymerase I PolA 30S ribosomal protein S1 RpsA Probable dephospho-CoA kinase CoaE (dephosphocoenzyme a kinase) Hypothetical protein Rv1632c Probable excinuclease ABC (subunit B-helicase) UvrB Possible drug efflux membrane protein Probable mannosyltransferase. Probable conserved transmembrane protein Iron-regulated universal stress protein family protein TB15.3 Conserved protein Probable excinuclease ABC (subunit A-DNA-binding ATPase) UvrA Conserved hypothetical protein Conserved hypothetical membrane protein Lysyl-tRNA synthetase 2 LysX Probable initiation factor if-3 InfC 50S ribosomal protein L35 RpmI 50S ribosomal protein L20 RplT Possible 23S rRNA methyltransferase TsnR Conserved hypothetical protein PE family protein PE17 Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) Probable transmembrane protein Probable phenylalanyl-tRNA synthetase, alpha chain PheS Probable phenylalanyl-tRNA synthetase, beta chain PheT PE-PGRS family protein PE_PGRS30 Probable N-acetyl-gamma-glutamyl-phoshate reductase ArgC Probable glutamate N-acetyltransferase ArgJ Probable acetylglutamate kinase ArgB Probable acetylornithine aminotransferase ArgD Probable ornithine carbamoyltransferase, anabolic ArgF Probable arginine repressor ArgR (AHRC) Probable argininosuccinate synthase ArgG Probable argininosuccinate lyase ArgH Chalcone synthase Pks10 Probable polyketide synthase Pks7 Probable polyketide synthase Pks8 Probable polyketide synthase Pks17 Probable polyketide synthase Pks9 Chalcone synthase Pks11 Probable cytochrome P450 139 Cyp139 Probable second part of macrolide-transport ATP-binding protein ABC transporter Probable first part of macrolide-transport ATP-binding protein ABC transporter Hypothetical protein Rv1669 Conserved hypothetical protein Probable membrane protein Probable conserved integral membrane transport protein Conserved hypothetical protein Probable transcriptional regulatory protein Probable transcriptional regulatory protein Cmr Unknown protein Probable conserved lipoprotein DsbF Probable integral membrane protein Possible acyl-CoA dehydrogenase FadE16 Hypothetical protein Rv1680 Possible molybdopterin biosynthesis protein MoeX Probable coiled-coil structural protein Possible bifunctional enzyme; long-chain acyl-CoA synthase and lipase Conserved hypothetical protein Conserved hypothetical protein Probable conserved integral membrane protein ABC transporter Probable conserved ATP-binding protein ABC transporter Possible 3-methyladenine DNA glycosylase Mpg Probable tyrosyl-tRNA synthase TyrS (TYRRS) Probable lipoprotein LprJ Conserved hypothetical protein Probable phosphatase Conserved hypothetical protein 2'-O-methyltransferase TlyA Inorganic polyphosphate/ATP-NAD kinase PpnK (poly(P)/ATP NAD kinase) Probable DNA repair protein RecN (recombination protein N) Conserved hypothetical protein Outer membrane protein MctB Probable CTP synthase PyrG NUDIX hydrolase Probable integrase/recombinase Conserved hypothetical protein Probable catechol-O-methyltransferase Probable D-serine/alanine/glycine transporter protein CycA PPE family protein PPE22 PPE family protein PPE23 Conserved hypothetical protein Probable conserved transmembrane protein Putative initiation inhibitor protein Possible segregation and condensation protein ScpA Possible segregation and condensation protein ScpB Conserved hypothetical protein Cytidylate kinase Cmk (CMP kinase) (cytidine monophosphate kinase) (ck) Probable GTP-binding protein EngA Probable oxidoreductase Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Probable transcriptional regulatory protein Possible toxin VapC12 Possible antitoxin VapB12 Possible carboxylase Probable hydrolase Hypothetical protein Rv1724c Conserved hypothetical protein Probable oxidoreductase Conserved hypothetical protein Conserved hypothetical protein Possible S-adenosylmethionine-dependent methyltransferase Possible penicillin-binding protein Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 Conserved protein Probable conserved transmembrane protein Conserved hypothetical protein Hypothetical membrane protein Probable nitrate reductase NarX Possible nitrate/nitrite transporter NarK2 Conserved protein Probable sulphate-transport transmembrane protein ABC transporter Possible antitoxin VapB34 Possible toxin VapC34. Contains PIN domain Unknown protein Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E) Probable membrane protein Probable isopentenyl-diphosphate delta-isomerase Idi (IPP isomerase) (isopentenyl pyrophosphate isomerase) Anchored-membrane serine/threonine-protein kinase PknF (protein kinase F) (STPK F) Probable conserved transmembrane ATP-binding protein ABC transporter Unknown protein Possible integral membrane protein Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable oxidoreductase Conserved hypothetical protein PPE family protein PPE24 Conserved protein Probable phospholipase C 4 (fragment) PlcD, partial Putative transposase, partial Putative transposase for insertion sequence element IS6110 (fragment) Probable cutinase Cut1 PE-PGRS family protein Wag22 Possible triacylglycerol synthase (diacylglycerol acyltransferase) Possible exported protein Unknown protein Putative transposase for insertion sequence element IS6110 (fragment) Putative transposase, partial Conserved hypothetical protein Putative transposase (fragment) Conserved protein Conserved protein PE-PGRS family protein PE_PGRS31 Conserved protein Conserved protein L-gulono-1,4-lactone dehydrogenase Hypothetical protein Rv1772 Probable transcriptional regulatory protein Probable oxidoreductase Conserved hypothetical protein Possible transcriptional regulatory protein Probable cytochrome P450 144 Cyp144 Unknown protein Possible integral membrane protein Conserved protein Probable 4-alpha-glucanotransferase MalQ (amylomaltase) (disproportionating enzyme) (D-enzyme) ESX conserved component EccB5. ESX-5 type VII secretion system protein. Probable membrane protein ESX conserved component EccC5. ESX-5 type VII secretion system protein Probable cytochrome P450 143 Cyp143 Probable ferredoxin PPE family protein PPE25 PE family protein PE18 PPE family protein PPE26 PPE family protein PPE27 PE family protein PE19 Putative ESAT-6 like protein EsxN (ESAT-6 like protein 5) Conserved protein ESX conserved component EccD5. ESX-5 type VII secretion system protein. Probable membrane protein Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) ESX conserved component EccE5. ESX-5 type VII secretion system protein. Probable membrane protein ESX conserved component EccA5. ESX-5 type VII secretion system protein Probable lipoprotein LppT PPE family protein PPE28 PPE family protein PPE29 PPE family protein PPE30 PE-PGRS family protein PE_PGRS32 Conserved protein Hypothetical protein Rv1805c PE family protein PE20 PPE family protein PPE31, partial PPE family protein PPE32 PPE family protein PPE33 Conserved protein Possible Mg2+ transport P-type ATPase C MgtC Probable dehydrogenase Conserved hypothetical protein Membrane-bound C-5 sterol desaturase Erg3 (sterol-C5-desaturase) Conserved protein Possible transcriptional regulatory protein Possible flavoprotein PE-PGRS family protein PE_PGRS33 Probable drug-transport transmembrane ATP-binding protein ABC transporter BacA Probable acetolactate synthase IlvG (acetohydroxy-acid synthase)(ALS) Possible preprotein translocase ATPase SecA2 Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA2 (PGP synthase) (phosphatidylglycerophosphate synthase) (3-phosphatidyl-1'-glycerol-3'phosphate synthase) Conserved protein Conserved hypothetical membrane protein Conserved protein Probable glycine cleavage system H protein GcvH Conserved protein with FHA domain, GarA Conserved protein Conserved protein Conserved hypothetical protein Hypothetical protein Rv1831 Probable glycine dehydrogenase GcvB (glycine decarboxylase) (glycine cleavage system P-protein) Possible haloalkane dehalogenase Probable hydrolase Conserved hypothetical protein Conserved protein Malate synthase G GlcB Possible toxin VapC13 Possible antitoxin VapB13 PE-PGRS family protein PE_PGRS34 Conserved hypothetical membrane protein Conserved hypothetical membrane protein Probable inosine-5'-monophosphate dehydrogenase GuaB1(imp dehydrogenase) (IMPDH) (IMPD) Probable 6-phosphogluconate dehydrogenase Gnd1 Possible sensor-transducer protein BlaR Transcriptional repressor BlaI Conserved protein Urease gamma subunit UreA (urea amidohydrolase) Urease beta subunit UreB (urea amidohydrolase) Urease alpha subunit UreC (urea amidohydrolase) Urease accessory protein UreF Urease accessory protein UreG Probable urease accessory protein UreD Probable NADH dehydrogenase Ndh Possible oxidoreductase Possible oxidoreductase Probable molybdate-binding lipoprotein ModA Probable molybdenum-transport integral membrane protein ABC transporter ModB Probable molybdenum-transport ATP-binding protein ABC transporter ModC Alanine and proline rich secreted protein Apa (fibronectin attachment protein) (immunogenic protein MPT32) (antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen) Probable conserved transmembrane protein Probable alcohol dehydrogenase AdhA Probable conserved integral membrane protein Conserved protein Probable short-chain type dehydrogenase Conserved protein Conserved protein Conserved hypothetical protein Probable reductase Conserved hypothetical protein Conserved protein Possible L-lactate dehydrogenase (cytochrome) LldD2 Conserved hypothetical protein Unknown protein Conserved protein Probable bacterioferritin BfrA Probable conserved integral membrane protein Probable glutamine synthetase GlnA3 (glutamine synthase) (GS-I) Conserved hypothetical protein Probable cytochrome P450 140 Cyp140 Possible conserved lipoprotein LppE Probable short-chain type dehydrogenase/reductase Conserved hypothetical protein Probable resuscitation-promoting factor RpfC Chorismate mutase Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular alpha-antigen) Hypothetical protein Rv1887 Possible transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv1890c Conserved protein Probable membrane protein Conserved hypothetical protein Conserved hypothetical protein Possible dehydrogenase Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Possible lipoprotein LppD Probable lignin peroxidase LipJ Probable CinA-like protein CinA Probable sialic acid-transport integral membrane protein NanT Probable conserved membrane protein Conserved hypothetical protein Probable D-amino acid oxidase Aao Conserved protein Hypothetical protein Rv1907c Catalase-peroxidase-peroxynitritase T KatG Ferric uptake regulation protein FurA (fur) Probable exported protein Probable lipoprotein LppC Possible oxidoreductase FadB5 Conserved hypothetical protein Unknown protein Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) PPE family protein PPE34 PPE family protein PPE35 Conserved protein Probable membrane protein Probable conserved lipoprotein LppF Probable conserved lipoprotein Probable lipase LipD Unknown protein Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Immunogenic protein Mpt63 (antigen Mpt63/MPB63) (16 kDa immunoprotective extracellular protein) Conserved hypothetical protein Probable short-chain type dehydrogenase/reductase Conserved hypothetical protein Conserved hypothetical protein Probable transcriptional regulatory protein Probable thiol peroxidase Tpx Probable acyl-CoA dehydrogenase FadE18 Probable acyl-CoA dehydrogenase FadE17 Possible enoyl-CoA hydratase EchA13 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Possible monooxygenase Possible oxygenase Probable epoxide hydrolase EphB (epoxide hydratase) Probable oxidoreductase Probable riboflavin biosynthesis protein RibA1 (GTP cyclohydrolase II) Probable short-chain type dehydrogenase/reductase Possible toxin MazF5 Possible antitoxin MazE5 Conserved protein Conserved hypothetical protein Possible lipoprotein Hypothetical protein Rv1947 Hypothetical protein Rv1948c Conserved hypothetical protein, partial Conserved hypothetical protein Conserved hypothetical protein Possible antitoxin VapB14 Possible toxin VapC14 Hypothetical protein Rv1954c Hypothetical protein Rv1954A Possible toxin HigB Possible antitoxin HigA Hypothetical protein Rv1957 Hypothetical protein Rv1958c Possible toxin ParE1 Possible antitoxin ParD1 Hypothetical protein Rv1961 Possible toxin VapC35. Contains PIN domain Possible antitoxin VapB35 Probable transcriptional repressor (probably TetR-family) Mce3R Conserved hypothetical integral membrane protein YrbE3A Conserved hypothetical integral membrane protein YrbE3B Mce-family protein Mce3A Mce-family protein Mce3B Mce-family protein Mce3C Mce-family protein Mce3D Possible Mce-family lipoprotein LprM (Mce-family lipoprotein Mce3E) Mce-family protein Mce3F Probable conserved Mce associated membrane protein Possible conserved Mce associated membrane protein Probable conserved membrane protein Conserved hypothetical protein Conserved hypothetical protein Conserved protein Conserved protein Possible conserved permease Immunogenic protein Mpt64 (antigen Mpt64/MPB64) Ribonucleoside-diphosphate reductase (beta chain) NrdF1 (ribonucleotide reductase small subunit) (R2F protein) Possible toxin VapC36. Contains PIN domain Possible antitoxin VapB36 PE-PGRS family protein PE_PGRS35 Probable cutinase precursor CFP21 Probable transcriptional regulatory protein (probably LysR-family) Probable conserved integral membrane protein Possible chitinase Probable 23S rRNA methyltransferase Erm(37) Hypothetical protein Rv1989c Probable transcriptional regulatory protein Possible dehydrogenase (fragment) Toxin MazF6 Antitoxin MazE6 Probable metal cation transporter P-type ATPase G CtpG Conserved protein Metal sensor transcriptional regulator CmtR (ArsR-SmtB family) Unknown protein Universal stress protein family protein Probable metal cation transporter P-type ATPase A CtpF Conserved protein Probable conserved integral membrane protein Unknown protein Conserved hypothetical protein Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) Conserved hypothetical protein Conserved protein Universal stress protein family protein Probable trehalose-6-phosphate phosphatase OtsB1 (trehalose-phosphatase) (TPP) Ferredoxin FdxA Conserved hypothetical protein Antitoxin VapB15 Toxin VapC15 Conserved hypothetical protein, probable transcription repressor Conserved hypothetical protein Transposase Transposase Conserved hypothetical protein Hypothetical protein Rv2016 Transcriptional regulatory protein Conserved protein Conserved protein Conserved hypothetical protein Transcriptional regulatory protein Conserved protein Hypothetical protein Rv2023c Conserved hypothetical protein Conserved membrane protein Universal stress protein family protein Two component sensor histidine kinase DosT Universal stress protein family protein 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) Conserved protein Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3) Conserved protein Acg Conserved hypothetical protein ArsR repressor protein Conserved hypothetical protein Conserved hypothetical protein Conserved transmembrane protein Probable sugar-transport ATP-binding protein ABC transporter Probable sugar-transport integral membrane protein ABC transporter Probable sugar-transport integral membrane protein ABC transporter Probable sugar-binding lipoprotein Conserved protein Pyrazinamidase/nicotinamidase PncA (PZase) Conserved hypothetical protein Carboxylesterase LipT Probable lipoprotein LppI Conserved hypothetical protein Polyketide synthase Pks12 Conserved hypothetical protein Conserved protein Polyprenol-monophosphomannose synthase Ppm1 Conserved protein Probable transmembrane protein FxsA Conserved protein 30S ribosomal protein S18 RpsR2 30S ribosomal protein S14 RpsN2 50S ribosomal protein L33 RpmG1 50S ribosomal protein L28 RpmB2 Conserved hypothetical protein Possible conserved integral membrane protein Conserved protein Cobalamin biosynthesis protein CobN Antitoxin MazE7 Possible toxin MazF7 Precorrin-3B synthase CobG Precorrin-8X methylmutase CobH (aka precorrin isomerase) Probable bifunctional protein, CobI-COBJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase Conserved protein Class a beta-lactamase BlaC RNA polymerase sigma factor, ECF subfamily, SigC Precorrin-6X reductase CobK Precorrin-3 methylase CobM (precorrin-4 C11-methyltransferase) Precorrin-6Y C(5,15)-methyltransferase (decarboxylating) CobL Probable shortchain dehydrogenase Possible pyridoxamine 5'-phosphate oxidase (PNP/PMP oxidase) (pyridoxinephosphate oxidase) (PNPOX) (pyridoxine 5'-phosphate oxidase) Possible hypothetical exported or envelope protein Conserved hypothetical protein Possible conserved transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Lipoprotein LppJ Conserved transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv2084 Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Transmembrane serine/threonine-protein kinase J PknJ (protein kinase J) (STPK J) Dipeptidase PepE Probable 5'-3' exonuclease Probable membrane protein ATP-dependent DNA helicase HelY Sec-independent protein translocase transmembrane protein TatC Sec-independent protein translocase membrane-bound protein TatA Proteasome accessory factor C PafC Proteasome accessory factor B PafB Proteasome accessory factor a PafA Conserved hypothetical protein Probable helicase HelZ Conserved hypothetical protein Possible toxin VapC37. Contains PIN domain Possible antitoxin VapB37 Putative transposase for insertion sequence element IS6110 (fragment) Probable transposase, partial PE family protein PE22 PPE family protein PPE36 Proteasome alpha subunit PrcA; assembles with beta subunit PrcB Proteasome beta subunit PrcB; assembles with alpha subunit PrcA Prokaryotic ubiquitin-like protein Pup Deamidase of pup Dop Probable integral membrane protein Conserved protein Mycobacterial proteasome ATPase Mpa Conserved lipoprotein LppK Conserved hypothetical protein RNA methyltransferase Conserved hypothetical protein Probable conserved integral membrane protein ATP phosphoribosyltransferase HisG Phosphoribosyl-AMP pyrophosphatase HisE PPE family protein PPE37 5-methyltetrahydrofolate--homocystein methyltransferase MetH (methionine synthase, vitamin-B12 dependent isozyme) (ms) Conserved hypothetical protein PE-PGRS family protein PE_PGRS37 L-asparagine permease AnsP1 Conserved transmembrane protein Probable oxidoreductase Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC Monophosphatase CysQ Conserved hypothetical protein Conserved hypothetical protein Conserved protein Conserved protein Possible conserved transmembrane protein Conserved hypothetical protein Probable conserved lipoprotein LppL Probable dihydroorotate dehydrogenase PyrD Conserved protein TB18.6 Conserved protein Possible toxin ParE2 Possible antitoxin ParD2 Conserved hypothetical protein Probable transmembrane protein Diviva family protein Wag31 Possible conserved transmembrane protein Conserved hypothetical protein Conserved protein Conserved protein YfiH Cell division protein FtsZ Possible cell division protein FtsQ Probable UDP-N-acetylmuramate-alanine ligase MurC Probable UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase MurG FtsW-like protein FtsW Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE Conserved protein Conserved hypothetical protein Conserved hypothetical protein Conserved protein PE-PGRS family protein PE_PGRS38 Probable penicillin-binding membrane protein PbpB Probable conserved proline rich membrane protein Conserved protein Conserved protein Probable transposase, partial Putative transposase for insertion sequence element IS6110 (fragment) Probable conserved transmembrane protein GCN5-related N-acetyltransferase Probable conserved lipoprotein LppM Conserved protein Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) Alpha(1-_6)mannosyltransferase. Possible conserved integral membrane protein Conserved regulatory protein Probable transmembrane serine/threonine-protein kinase L PknL (protein kinase L) (STPK L) Possible transposase 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible) Conserved hypothetical protein Probable conserved integral membrane protein Alpha(1-_2)mannosyltransferase 1-acylglycerol-3-phosphate O-acyltransferase Conserved protein Conserved hypothetical protein Conserved protein TB16.3 Conserved hypothetical protein Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Mannosyltransferase PimB Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Probable anthranilate phosphoribosyltransferase TrpD Probable cytochrome C oxidase (subunit III) CtaE Probable ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit) Probable rieske iron-sulfur protein QcrA Probable ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) Probable conserved transmembrane protein Probable conserved membrane protein MmpS3 Possible conserved integral membrane protein Probable transmembrane cytochrome C oxidase (subunit II) CtaC Probable asparagine synthetase AsnB Adenosine kinase Possible conserved membrane protein Conserved protein Conserved hypothetical protein Probable conserved transmembrane protein Probable nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase CobT Probable cobalamin 5'-phosphate synthase CobS Probable conserved integral membrane protein Branched-chain amino acid transaminase IlvE Probable aminomethyltransferase GcvT (glycine cleavage system T protein) Adenylyl cyclase (ATP pyrophosphate-lyase) (adenylate cyclase) Probable aminopeptidase PepB Possible short-chain dehydrogenase EphD DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase Conserved protein Probable lipoate biosynthesis protein B LipB Probable lipoate biosynthesis protein A LipA Probable conserved transmembrane protein Probable conserved membrane protein Glutamine synthetase GlnA1 (glutamine synthase) (GS-I) Glutamate-ammonia-ligase adenylyltransferase GlnE (glutamine-synthetase adenylyltransferase) Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II) Probable exported protease Probable carboxylesterase CaeA 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB Conserved protein Conserved hypothetical protein Multifunctional protein. Has RNASE H,alpha-ribazole phosphatase, and acid phosphatase activities Conserved protein Conserved protein Possible aminotransferase CobC Possible toxin VapC16 Possible antitoxin VapB16 Protein tyrosine kinase transcriptional regulatory protein PtkA Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) Probable conserved transmembrane protein Probable cobalamin biosynthesis transmembrane protein CobD Conserved protein Conserved protein Probable peroxiredoxin AhpE Conserved hypothetical protein Unknown protein Pyruvate dehydrogenase E1 component AceE (pyruvate decarboxylase) (pyruvate dehydrogenase) (pyruvic dehydrogenase) Conserved hypothetical protein Malonyl CoA-acyl carrier protein transacylase FabD (malonyl CoA:ACPM acyltransferase) (MCT) Meromycolate extension acyl carrier protein AcpM 3-oxoacyl-[acyl-carrier protein] synthase 1 KasA (beta-ketoacyl-ACP synthase) (KAS I) 3-oxoacyl-[acyl-carrier protein] synthase 2 KasB (beta-ketoacyl-ACP synthase) (KAS I) Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 Conserved hypothetical protein Probable glycerol-3-phosphate dehydrogenase GlpD1 Possible transcriptional regulatory protein Possible flavoprotein Possible flavoprotein Diacylglycerol kinase Possible secreted unknown protein Probable integral membrane protein Hypothetical protein Rv2255c Conserved hypothetical protein Conserved protein Possible transcriptional regulatory protein S-nitrosomycothiol reductase MscR Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Possible oxidoreductase Conserved hypothetical proline rich protein Possible conserved integral membrane protein Probable cytochrome P450 124 Cyp124 Conserved hypothetical protein Probable cytochrome P450 128 Cyp128 Hypothetical protein Rv2269c Probable lipoprotein LppN Conserved hypothetical protein Probable conserved transmembrane protein Probable conserved transmembrane protein Possible toxin MazF8 Possible antitoxin MazE8 Conserved hypothetical protein Cytochrome P450 121 Cyp121 Possible glycerolphosphodiesterase Putative transposase for insertion sequence element IS6110 (fragment) Probable transposase, partial Probable dehydrogenase Putative phosphate-transport permease PitB Probable transcription regulator (LysR family) Hypothetical protein Rv2283 Probable esterase LipM Possible triacylglycerol synthase (diacylglycerol acyltransferase) Conserved hypothetical protein Probable conserved integral membrane transport protein YjcE Hypothetical protein Rv2288 Probable CDP-diacylglycerol pyrophosphatase Cdh (CDP-diacylglycerol diphosphatase) (CDP-diacylglycerol phosphatidylhydrolase) Probable conserved lipoprotein LppO Probable thiosulfate sulfurtransferase SseB Hypothetical protein Rv2292c Conserved hypothetical protein Probable aminotransferase Conserved hypothetical protein Probable haloalkane dehalogenase Unknown protein Conserved protein Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Conserved protein Probable cutinase Cut2 Conserved protein Probable antibiotic-resistance protein Hypothetical protein Rv2304c Unknown protein Possible conserved membrane protein Possible conserved membrane protein Conserved hypothetical protein Hypothetical glycine rich protein Hypothetical glycine rich protein Hypothetical protein Rv2307D Conserved hypothetical protein Possible integrase (fragment) Hypothetical protein Rv2309A Possible excisionase Conserved hypothetical protein Hypothetical protein Rv2312 Hypothetical protein Rv2313c Conserved protein Conserved protein Probable sugar-transport integral membrane protein ABC transporter UspA Probable sugar-transport integral membrane protein ABC transporter UspB Probable periplasmic sugar-binding lipoprotein UspC Universal stress protein family protein Probable cationic amino acid transport integral membrane protein RocE Probable ornithine aminotransferase (C-terminus part) RocD2 (ornithine--oxo-acid aminotransferase) Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) Conserved protein Probable transcriptional regulatory protein (probably AsnC-family) Conserved hypothetical protein Possible transmembrane ATP-binding protein ABC transporter Conserved protein PE family protein PE23 Probable nitrite extrusion protein 1 NarK1 (nitrite facilitator 1) Probable lipoprotein LppP Hypothetical protein Rv2331 Hypothetical protein Rv2331A Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarboxylating)) (pyruvic-malic carboxylase) (NAD-me) Integral membrane drug efflux protein Stp Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thiol)-lyase A) (CSASE A) Probable serine acetyltransferase CysE (sat) Hypothetical protein Rv2336 Hypothetical protein Rv2337c Possible molybdopterin biosynthesis protein MoeW Probable conserved transmembrane transport protein MmpL9 PE-PGRS family protein PE_PGRS39 Probable conserved lipoprotein LppQ Conserved hypothetical protein Probable DNA primase DnaG Probable deoxyguanosine triphosphate triphosphohydrolase Dgt (dGTPase) (dGTP triphosphohydrolase) Possible conserved transmembrane protein Putative ESAT-6 like protein EsxO (ESAT-6 like protein 6) Putative ESAT-6 like protein EsxP (ESAT-6 like protein 7) Hypothetical protein Rv2348c Probable phospholipase C 3 PlcC Membrane-associated phospholipase C 2 PlcB Membrane-associated phospholipase C 1 PlcA (MTP40 antigen) PPE family protein PPE38 PPE family protein PPE39 Probable transposase for insertion sequence element IS6110 (fragment) Probable transposase, partial PPE family protein PPE40 Probable glycyl-tRNA synthetase GlyS (glycine--tRNA ligase) (GLYRS) Probable transcriptional regulatory protein SmtB (probably ArsR-family) Probable zinc uptake regulation protein Zur Unknown protein Long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl diphosphate synthase) Possible DNA repair protein RecO Probable amidase AmiA2 (aminohydrolase) Probable GTP-binding protein Era Conserved hypothetical protein Probable conserved transmembrane protein Conserved hypothetical protein Probable PHOH-like protein PhoH1 (phosphate starvation-inducible protein PSIH) Hypothetical protein Rv2369c Conserved hypothetical protein PE-PGRS family protein PE_PGRS40 Conserved hypothetical protein Probable chaperone protein DnaJ2 Probable heat shock protein transcriptional repressor HrcA Conserved hypothetical protein Low molecular weight antigen CFP2 (low molecular weight protein antigen 2) (CFP-2) Putative conserved protein MbtH Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase) Peptide synthetase MbtF (peptide synthase) Peptide synthetase MbtE (peptide synthase) Polyketide synthetase MbtD (polyketide synthase) Polyketide synthetase MbtC (polyketide synthase) Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Putative acetyl hydrolase MbtJ Isochorismate synthase MbtI Conserved protein Probable oxygen-independent coproporphyrinogen III oxidase HemN (coproporphyrinogenase) (coprogen oxidase) Probable resuscitation-promoting factor RpfD Conserved hypothetical protein Ferredoxin-dependent sulfite reductase SirA Probable 3'-phosphoadenosine 5'-phosphosulfate reductase CysH (PAPS reductase, thioredoxin DEP.) (padops reductase) (3'-phosphoadenylylsulfate reductase) (PAPS sulfotransferase) Ferrochelatase Che1 Probable gamma-glutamyltranspeptidase precursor GgtB (gamma-glutamyltransferase) (glutamyl transpeptidase) Probable conserved integral membrane protein Acid and phagosome regulated protein A AprA Acid and phagosome regulated protein B AprB PE-PGRS family protein PE_PGRS41 Sulfate-transport ATP-binding protein ABC transporter CysA1 Probable sulfate-transport integral membrane protein ABC transporter CysW Probable sulfate-transport integral membrane protein ABC transporter CysT Probable sulfate-binding lipoprotein SubI Hypothetical protein Rv2401 Possible conserved membrane protein Conserved protein Probable conserved lipoprotein LppR Probable GTP-binding protein LepA (GTP-binding elongation factor) Conserved protein Conserved protein Conserved hypothetical protein Possible PE family-related protein PE24 Conserved protein Conserved protein Conserved hypothetical protein 30S ribosomal protein S20 RpsT Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Enhanced intracellular survival protein Eis,GCN5-related N-acetyltransferase Conserved protein Unknown protein Glucosyl-3-phosphoglycerate phosphatase GpgP Conserved hypothetical protein Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nicotinate mononucleotide adenylyltransferase) (NAMN adenylyltransferase) Hypothetical protein Rv2422 Hypothetical protein Rv2423 Probable transposase Conserved hypothetical protein Conserved hypothetical protein Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) Alkyl hydroperoxide reductase C protein AhpC (alkyl hydroperoxidase C) Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D) PPE family protein PPE41 PE family protein PE25 Hypothetical protein Rv2432c Hypothetical protein Rv2433c Probable conserved transmembrane protein Probable cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-) Ribokinase RbsK Conserved transmembrane protein Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) Conserved hypothetical protein Probable glutamate 5-kinase protein ProB (gamma-glutamyl kinase) (GK) Probable GTP1/Obg-family GTP-binding protein Obg 50S ribosomal protein L27 RpmA 50S ribosomal protein L21 RplU Probable C4-dicarboxylate-transport transmembrane protein DctA Possible ribonuclease E Rne Probable nucleoside diphosphate kinase NdkA (NDK) (NDP kinase) (nucleoside-2-P kinase) Probable conserved integral membrane protein Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) Probable valyl-tRNA synthase protein ValS (valyl-tRNA synthetase) (valine--tRNA ligase) (valine translase) Conserved protein Probable resuscitation-promoting factor RpfE Hypothetical proline and serine rich protein Hypothetical protein Rv2452c Probable molybdopterin-guanine dinucleotide biosynthesis protein A MobA Probable oxidoreductase (beta subunit) Probable oxidoreductase (alpha subunit) Probable conserved integral membrane transport protein Probable ATP-dependent CLP protease ATP-binding subunit ClpX Probable homocysteine S-methyltransferase MmuM (S-methylmethionine:homocysteine methyltransferase) (cysteine methyltransferase) Probable conserved integral membrane transport protein Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) Probable trigger factor (TF) protein Tig Probable esterase/lipase LipP Possible DNA glycosylase Ribose-5-phosphate isomerase Conserved protein Probable aminopeptidase N PepN (Lysyl aminopeptidase) (LYS-AP) (alanine aminopeptidase) Conserved protein Conserved protein Conserved hypothetical protein Globin (oxygen-binding protein) GlbO Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidase) (acid maltase) Conserved hypothetical protein Possible alanine and proline rich membrane protein Conserved hypothetical protein Conserved protein Probable NAD-dependent glutamate dehydrogenase Gdh (NAD-Gdh) (NAD-dependent glutamic dehydrogenase) Probable macrolide-transport ATP-binding protein ABC transporter Conserved hypothetical protein Probable transposase, partial Possible transposase for insertion sequence element IS6110 (fragment) Hypothetical protein Rv2481c Probable glycerol-3-phosphate acyltransferase PlsB2 (GPAT) Possible transmembrane phospholipid biosynthesis bifunctional enzyme PlsC: putative L-3-phosphoserine phosphatase (O-phosphoserine phosphohydrolase) (PSP) (pspase) + 1-acyl-SN-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (lysophosphatidic acid acyltransferase) (LPAAT) Possible triacylglycerol synthase (diacylglycerol acyltransferase) Probable carboxylesterase LipQ Probable enoyl-CoA hydratase EchA14 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) PE-PGRS family protein PE_PGRS42 Probable transcriptional regulatory protein (LuxR-family) Hypothetical alanine rich protein PE-PGRS family protein PE_PGRS43 Conserved hypothetical protein Hypothetical protein Rv2492 Possible antitoxin VapB38 Possible toxin VapC38. Contains PIN domain Probable branched-chain keto acid dehydrogenase E2 component BkdC Probable branched-chain keto acid dehydrogenase E1 component, beta subunit BkdB Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) Possible oxidase regulatory-related protein Possible acyl-CoA dehydrogenase FadE19 (MMGC) Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA1: biotin carboxylase + biotin carboxyl carrier protein (BCCP) Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD1 Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (beta subunit) ScoB (3-oxo-acid:CoA transferase) (OXCT B) (succinyl CoA:3-oxoacid CoA-transferase) Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (alpha subunit) ScoA (3-oxo acid:CoA transferase) (OXCT A) (succinyl-CoA:3-oxoacid-coenzyme A transferase) Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable transcriptional regulatory protein (probably TetR-family) Possible conserved proline rich membrane protein Probable conserved integral membrane leucine and alanine rich protein Probable short-chain type dehydrogenase/reductase Conserved protein Oligoribonuclease Orn Transposase for insertion sequence element IS1081 Hypothetical protein Rv2513 Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv2516c Unknown protein Probable L,D-transpeptidase LdtB PE family protein PE26 Possible conserved membrane protein Probable bacterioferritin comigratory protein Bcp Conserved hypothetical protein holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) Probable fatty acid synthase Fas (fatty acid synthetase) Conserved hypothetical protein. Secreted; predicted to be a substrate of the twin arginine translocation (tat) export system Possible antitoxin VapB17 Possible toxin VapC17 Probable restriction system protein Mrr Hypothetical protein Rv2529 Possible toxin VapC39. Contains PIN domain Possible antitoxin VapB39 Probable amino acid decarboxylase Hypothetical protein Rv2532c N utilization substance protein NusB (NusB protein) Probable elongation factor P Efp Probable cytoplasmic peptidase PepQ Probable conserved transmembrane protein 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 3-dehydroquinate synthase AroB Shikimate kinase AroK (SK) Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) Hypothetical alanine rich protein Conserved hypothetical protein Probable conserved lipoprotein LppA Probable conserved lipoprotein LppB Possible antitoxin VapB18 Possible toxin VapC18 Possible antitoxin VapB19 Possible toxin VapC19 Conserved protein Possible toxin VapC20 Possible antitoxin VapB20 Conserved hypothetical protein Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase) Probable conserved membrane protein Conserved protein Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS) Conserved hypothetical protein Conserved protein Conserved protein Conserved hypothetical alanine leucine valine rich protein Probable proline and glycine rich transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Probable glutamine-transport transmembrane protein ABC transporter Probable glutamine-transport ATP-binding protein ABC transporter GlnQ Conserved protein Long conserved protein Conserved hypothetical alanine and leucine rich protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Probable transmembrane alanine and valine and leucine rich protein Probable aspartyl-tRNA synthetase AspS (aspartate--tRNA ligase) (ASPRS) (aspartic acid translase) Conserved hypothetical protein Conserved protein Possible conserved membrane glycine rich protein Possible conserved membrane protein Conserved protein Conserved hypothetical protein Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) Probable histidyl-tRNA synthetase HisS (histidine--tRNA ligase) (HISRS) (histidine--translase) Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) Probable peptidyl-prolyl cis-trans isomerase B PpiB (cyclophilin) (PPIase) (rotamase) (peptidylprolyl isomerase) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) Possible conserved lipoprotein Probable protein-export membrane protein SecF Probable protein-export membrane protein SecD Probable conserved membrane protein secretion factor YajC 4-aminobutyrate aminotransferase GabT (gamma-amino-N-butyrate transaminase) (GABA transaminase) (glutamate:succinic semialdehyde transaminase) (GABA aminotransferase) (GABA-at) Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) PE-PGRS family protein PE_PGRS44 Probable holliday junction DNA helicase RuvB Probable holliday junction DNA helicase RuvA Probable crossover junction endodeoxyribonuclease RuvC (holliday junction nuclease) (holliday junction resolvase) Possible antitoxin VapB40 Possible toxin VapC40. Contains PIN domain Probable membrane protein Conserved hypothetical protein Probable conserved membrane protein Probable conserved integral membrane protein Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) Possible antitoxin VapB41 Possible toxin VapC41. Contains PIN domain Highly conserved protein Probable glutamine amidotransferase SnoP Probable acyl-CoA thioesterase II TesB2 (TEII) Possible pyridoxine biosynthesis protein SnzP Probable pyridoxamine 5'-phosphate oxidase PdxH (PNP/PMP oxidase) (pyridoxinephosphate oxidase) (PNPOX) (pyridoxine 5'-phosphate oxidase) PPE family protein PPE42 Probable conserved membrane protein Alpha-mannosyltransferase PimA Probable acyltransferase PI synthase PgsA1 (phosphatidylinositol synthase) (CDP-diacylglycerol--inositol-3-phosphatidyltransferase) Conserved protein Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) Conserved hypothetical protein PE-PGRS family protein PE_PGRS45 Conserved protein Probable transmembrane protein Conserved hypothetical protein Conserved protein Probable conserved transmembrane protein Possible transcriptional regulatory protein Possible methyltransferase (methylase) Universal stress protein family protein TB31.7 Universal stress protein family protein Probable conserved transmembrane alanine and leucine rich protein Hypoxic response protein 1 Hrp1 Conserved protein Hypothetical protein Rv2628 Conserved protein Hypothetical protein Rv2630 Conserved hypothetical protein Conserved protein Hypothetical protein Rv2633c PE-PGRS family protein PE_PGRS46 Hypothetical protein Rv2635 Conserved hypothetical protein Possible transmembrane protein DedA Conserved hypothetical protein Probable conserved integral membrane protein Possible transcriptional regulatory protein (probably ArsR-family) Cadmium inducible protein CadI Possible transcriptional regulatory protein (probably ArsR-family) Probable arsenic-transport integral membrane protein ArsC Hypothetical protein Rv2644c Hypothetical protein Rv2645 Probable integrase Hypothetical protein Rv2647 Probable transposase for insertion sequence element IS6110 (fragment) Probable transposase for insertion sequence element IS6110, partial Possible PhiRv2 prophage protein Possible PhiRv2 prophage protease Probable PhiRv2 prophage protein Possible PhiRv2 prophage protein Possible PhiRv2 prophage protein Possible PhiRv2 prophage protein Possible PhiRv2 prophage protein Probable PhiRv2 prophage protein Possible prophage protein Probable PhiRv2 prophage integrase Hypothetical protein Rv2660c Hypothetical protein Rv2661c Hypothetical protein Rv2662 Hypothetical protein Rv2663 Hypothetical protein Rv2664 Hypothetical arginine rich protein Probable transposase for insertion sequence element IS1081 (fragment) Possible ATP-dependent protease ATP-binding subunit ClpC2 Possible exported alanine and valine rich protein GCN5-related N-acetyltransferase Conserved hypothetical protein Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase) Possible secreted protease Possible arabinofuranosyltransferase AftC Probable peptide methionine sulfoxide reductase MsrB (protein-methionine-R-oxide reductase) (peptide met(O) reductase) Conserved hypothetical protein Conserved protein Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) Probable uroporphyrinogen decarboxylase HemE (uroporphyrinogen III decarboxylase) (URO-D) (UPD) Probable enoyl-CoA hydratase EchA15 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Conserved protein Conserved hypothetical alanine rich protein Probable 1-deoxy-D-xylulose 5-phosphate synthase Dxs1 (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS) Conserved protein Probable arsenic-transport integral membrane protein ArsA Probable arsenic-transport integral membrane protein ArsB1 Antibiotic-transport integral membrane leucine and alanine and valine rich protein ABC transporter Antibiotic-transport integral membrane leucine and valine rich protein ABC transporter Antibiotic-transport ATP-binding protein ABC transporter Conserved alanine and valine and glycine rich protein Probable conserved integral membrane alanine and valine and leucine rich protein TRK system potassium uptake protein CeoB TRK system potassium uptake protein CeoC Probable conserved integral membrane alanine and leucine rich protein Conserved protein Conserved hypothetical alanine rich protein Conserved alanine and glycine and valine rich protein Probable deoxyuridine 5'-triphosphate nucleotidohydrolase Dut (dUTPase) (dUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (dUTP diphosphatase) (deoxyuridine-triphosphatase) Probable conserved alanine rich transmembrane protein Conserved hypothetical protein Possible conserved secreted alanine rich protein Inositol-1-monophosphatase SuhB Polyphosphate glucokinase PpgK (polyphosphate-glucose phosphotransferase) RNA polymerase sigma factor SigA (sigma-A) Conserved protein Conserved hypothetical protein Hypothetical protein Rv2706c Probable conserved transmembrane alanine and leucine rich protein Conserved hypothetical protein Probable conserved transmembrane protein RNA polymerase sigma factor SigB Iron-dependent repressor and activator IdeR Hypothetical protein Rv2712c Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleotide transhydrogenase) Conserved alanine and leucine rich protein Possible hydrolase Conserved protein Conserved protein Probable transcriptional regulatory protein NrdR Possible conserved membrane protein Repressor LexA Possible conserved transmembrane alanine and glycine rich protein Conserved hypothetical protein Probable conserved integral membrane protein Probable acyl-CoA dehydrogenase FadE20 Probable GTP-binding protein HflX Probable diaminopimelate epimerase DapF (DAP epimerase) Probable tRNA delta(2)-isopentenylpyrophosphate transferase MiaA (IPP transferase) (isopentenyl-diphosphate:tRNA isopentenyltransferase) (iptase) (IPPT) Conserved alanine rich protein Probable conserved integral membrane alanine valine and leucine rich protein Hypothetical protein Rv2730 Conserved alanine and arginine rich protein Probable conserved transmembrane protein Conserved hypothetical alanine, arginine-rich protein Conserved hypothetical protein Conserved hypothetical protein Regulatory protein RecX RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)] Conserved hypothetical cysteine rich protein (fragment) Conserved hypothetical protein Possible alanine rich transferase Epoxide hydrolase PE-PGRS family protein PE_PGRS47 Conserved hypothetical arginine rich protein Possible conserved transmembrane alanine rich protein Conserved 35 kDa alanine rich protein Transcriptional regulatory protein ClgR Probable PGP synthase PgsA3 (CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase) (phosphatidylglycerophosphate synthase) Probable L-glutamate alpha-N-acetyltranferase ArgA (alpha-N-acetylglutamate synthase) Possible cell division transmembrane protein FtsK Conserved protein Probable dehydrogenase Conserved protein Conserved hypothetical protein Probable dihydrodipicolinate synthase DapA (DHDPS) (dihydrodipicolinate synthetase) Probable thymidylate synthase ThyX (ts) (TSase) Possible type I restriction/modification system specificity determinant (fragment) HsdS.1 (S protein) Possible type I restriction/modification system DNA methylase HsdM (M protein) (DNA methyltransferase) Possible toxin VapC21 Possible antitoxin VapB21 Possible toxin VapC42. Contains PIN domain Possible antitoxin VapB42 Possible type I restriction/modification system specificity determinant HsdS (S protein) Conserved hypothetical protein Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) Probable thymidylate synthase ThyA (ts) (TSASE) Probable alanine rich hydrolase Probable short-chain type dehydrogenase/reductase Possible membrane protein PPE family protein PPE43 PE family protein PE27 PPE family protein PPE44 Conserved hypothetical protein Probable conserved transmembrane protein Dihydrodipicolinate reductase DapB (DHPR) Hypothetical protein Rv2774c GCN5-related N-acetyltransferase Probable oxidoreductase Conserved hypothetical protein Conserved protein Possible transcriptional regulatory protein (probably Lrp/AsnC-family) Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) Possible alanine rich oxidoreductase Probable zinc protease PepR Bifunctional protein polyribonucleotide nucleotidyltransferase GpsI: guanosine pentaphosphate synthetase + polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) (pnpase) Probable lipoprotein LppU 30S ribosomal protein S15 RpsO Probable bifunctional FAD synthetase/riboflavin biosynthesis protein RibF: riboflavin kinase (flavokinase) + FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)(FAD diphosphorylase) (flavin adenine dinucleotide synthetase) Conserved hypothetical alanine rich protein Probable transcriptional repressor SirR Probable acyl-CoA dehydrogenase FadE21 Probable lipid-transfer protein Ltp1 Probable transposase Possible resolvase Probable tRNA pseudouridine synthase B TruB (tRNA pseudouridine 55 synthase) (PSI55 synthase) (pseudouridylate synthase) (uracil hydrolyase) Phosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) Conserved hypothetical protein Probable conserved lipoprotein LppV Conserved hypothetical protein Conserved hypothetical protein Probable membrane protein Possible hydrolase Toxin MazF9 Possible antitoxin MazE9 Hypothetical arginine and alanine rich protein Conserved hypothetical protein Hypothetical protein Rv2804c Conserved hypothetical protein Possible membrane protein Conserved hypothetical protein Hypothetical protein Rv2808 Hypothetical protein Rv2809 Probable transposase, partial Conserved hypothetical protein Probable transposase Conserved hypothetical protein Probable transposase, partial Probable transposase Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv2818c Hypothetical protein Rv2819c Hypothetical protein Rv2820c Conserved hypothetical protein Hypothetical protein Rv2822c Conserved protein Hypothetical protein Rv2824c Conserved hypothetical protein Hypothetical protein Rv2826c Hypothetical protein Rv2827c Conserved hypothetical protein Conserved hypothetical protein Possible toxin VapC22 Possible antitoxin VapB22 Probable enoyl-CoA hydratase EchA16 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable Sn-glycerol-3-phosphate transport ATP-binding protein ABC transporter UgpC Probable Sn-glycerol-3-phosphate-binding lipoprotein UgpB Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpE Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpA Possible DNA-damage-inducible protein F DinF Conserved protein Probable ribosome-binding factor a RbfA (P15B protein) Probable translation initiation factor if-2 InfB Conserved hypothetical protein Probable N utilization substance protein A NusA Conserved protein Probable conserved transmembrane alanine rich protein Conserved alanine rich protein Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase) Possible integral membrane efflux protein EfpA Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase Probable cobyrinic acid A,C-diamide synthase CobB Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity) Possible magnesium chelatase GCN5-related N-acetyltransferase Probable malate:quinone oxidoreductase Mqo (malate dehydrogenase [acceptor]) PE-PGRS family protein PE_PGRS48 Unknown protein NADPH-dependent mycothiol reductase Mtr Possible nickel-transport integral membrane protein NicT Probable short-chain type dehydrogenase/reductase Probable aldehyde dehydrogenase AldC Possible amidotransferase Probable glutamine synthetase GlnA4 (glutamine synthase) (GS-II) Methionine aminopeptidase MapB (map) (peptidase M) Conserved hypothetical protein Possible antitoxin VapB23 Possible toxin VapC23 Possible penicillin-binding lipoprotein Antitoxin RelF Toxin RelG GCN5-related N-acetyltransferase Probable GcpE protein Membrane bound metalloprotease Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomerase) Possible antitoxin VapB43 Possible toxin VapC43. Contains PIN domain Cell surface lipoprotein Mpt83 (lipoprotein P23) Possible integral membrane C-type cytochrome biogenesis protein DipZ Major secreted immunogenic protein Mpt70 Possible conserved transmembrane protein Probable conserved integral membrane protein Soluble secreted antigen Mpt53 precursor Conserved hypothetical protein, partial Conserved hypothetical protein Probable integral membrane phosphatidate cytidylyltransferase CdsA (CDP-diglyceride synthetase) (CDP-diglyceride pyrophosphorylase) (CDP-diacylglycerol synthase) (CDS) (CTP:phosphatidate cytidylyltransferase) (CDP-DAG synthase) (CDP-DG synthetase) Ribosome recycling factor Frr (ribosome releasing factor) (RRF) Probable uridylate kinase PyrH (UK) (uridine monophosphate kinase) (UMP kinase) Probable transcriptional regulatory protein Probable transposase Probable resolvase Probable transcriptional regulatory protein Probable amidase AmiC (aminohydrolase) Probable elongation factor Tsf (EF-ts) 30S ribosomal protein S2 RpsB Conserved hypothetical protein PPE family protein PPE45 Possible oxidoreductase Probable integrase/recombinase XerC Possible mycobactin utilization protein ViuB Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Possible FdhD protein homolog Possible formate dehydrogenase H FdhF (formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide) (formate dehydrogenase-H alpha subunit) (FDH-H) Conserved protein Probable ribonuclease HII protein RnhB (RNase HII) Probable signal peptidase I LepB (SPASE I) (leader peptidase I) 50S ribosomal protein L19 RplS Probable conserved alanine rich lipoprotein LppW Probable tRNA (guanine-N1)-methyltransferase TrmD (M1G-methyltransferase) (tRNA [GM37] methyltransferase) Probable 16S rRNA processing protein RimM Conserved hypothetical protein 30S ribosomal protein S16 RpsP Conserved hypothetical protein Probable penicillin-binding protein DacB2 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase) Probable transcriptional regulatory protein (probably TetR-family) Possible D-amino acid aminohydrolase (D-amino acid hydrolase) Probable transmembrane serine/threonine-protein kinase I PknI (protein kinase I) (STPK I) (phosphorylase B kinase kinase) (hydroxyalkyl-protein kinase) Conserved protein Probable signal recognition particle protein Ffh (fifty-four homolog) (SRP protein) Conserved hypothetical alanine and arginine rich protein Probable [protein-PII] uridylyltransferase GlnD (PII uridylyl-transferase) (uridylyl removing enzyme) (UTASE) Probable nitrogen regulatory protein P-II GlnB Probable ammonium-transport integral membrane protein Amt Probable cell division protein FtsY (SRP receptor) (signal recognition particle receptor) Probable chromosome partition protein Smc Probable acylphosphatase AcyP (acylphosphate phosphohydrolase) Conserved protein Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase) Probable ribonuclease III Rnc (RNase III) Conserved protein Conserved hypothetical protein Probable thioesterase TesA Hypothetical protein Rv2929 Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Phenolpthiocerol synthesis type-I polyketide synthase PpsA Phenolpthiocerol synthesis type-I polyketide synthase PpsB Phenolpthiocerol synthesis type-I polyketide synthase PpsC Phenolpthiocerol synthesis type-I polyketide synthase PpsD Phenolpthiocerol synthesis type-I polyketide synthase PpsE Daunorubicin-dim-transport ATP-binding protein ABC transporter DrrA Daunorubicin-dim-transport integral membrane protein ABC transporter DrrB Probable daunorubicin-dim-transport integral membrane protein ABC transporter DrrC Possible conserved polyketide synthase associated protein PapA5 Probable multifunctional mycocerosic acid synthase membrane-associated Mas Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Conserved transmembrane transport protein MmpL7 Probable transposase for insertion sequence element IS1533 Possible transposase Possible transposase for insertion sequence element IS1533 Probable conserved lipoprotein LppX Probable polyketide synthase Pks1 Probable polyketide synthase Pks15 P-hydroxybenzoyl-AMP ligase FadD22 Chorismate pyruvate lyase Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Possible oxidoreductase Possible methyltransferase (methylase) Enoyl reductase Hypothetical protein Rv2954c Conserved protein Conserved protein Possible glycosyl transferase Possible glycosyl transferase Possible methyltransferase (methylase) Hypothetical protein Rv2960c Probable transposase Possible glycosyl transferase Probable integral membrane protein Probable formyltetrahydrofolate deformylase PurU (formyl-FH(4) hydrolase) Probable phosphopantetheine adenylyltransferase KdtB (pantetheine-phosphate adenylyltransferase) (PPAT) (dephospho-CoA pyrophosphorylase) Possible methyltransferase (methylase) Probable pyruvate carboxylase Pca (pyruvic carboxylase) Probable conserved integral membrane protein Possible conserved membrane or secreted protein Probable lipase/esterase LipN Conserved hypothetical protein Probable oxidoreductase Possible conserved membrane or exported protein Probable ATP-dependent DNA helicase RecG Conserved hypothetical alanine rich protein Conserved hypothetical protein Probable uracil-DNA glycosylase Ung (UDG) Probable thiamine-monophosphate kinase ThiL (thiamine-phosphate kinase) Probable transposase Probable resolvase Possible conserved secreted protein Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase) Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA2 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) Conserved hypothetical alanine rich protein Polyphosphate kinase PPK (polyphosphoric acid kinase) (ATP-polyphosphate phosphotransferase) Possible hydrolase MutT1 DNA-binding protein HU homolog HupB (histone-like protein) (HLP) (21-kDa laminin-2-binding protein) Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) Probable transcriptional regulatory protein Hypothetical protein Rv2990c Conserved protein Glutamyl-tRNA synthetase GltS (glutamate--tRNA ligase) (glutamyl-tRNA synthase) (GLURS) Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) Probable conserved integral membrane protein Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Probable D-3-phosphoglycerate dehydrogenase SerA1 (PGDH) Possible alanine rich dehydrogenase Hypothetical protein Rv2998 Conserved hypothetical protein Probable conserved lipoprotein LppY Possible conserved transmembrane protein Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) (alpha-keto-beta-hydroxylacil reductoisomerase) Probable acetolactate synthase (small subunit) IlvN (acetohydroxy-acid synthase) (AHAS) (ALS) Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase) Low molecular weight protein antigen 6 (CFP-6) Conserved hypothetical protein Probable conserved lipoprotein LppZ Possible oxidoreductase Hypothetical protein Rv3008 Probable glutamyl-tRNA(GLN) amidotransferase (subunit B) GatB (Glu-ADT subunit B) Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) Probable glutamyl-tRNA(GLN) amidotransferase (subunit A) GatA (Glu-ADT subunit A) Probable glutamyl-tRNA(GLN) amidotransferase (subunit C) GatC (Glu-ADT subunit C) Conserved protein DNA ligase [NAD dependent] LigA (polydeoxyribonucleotide synthase [NAD+]) Conserved hypothetical protein Probable lipoprotein LpqA ESAT-6 like protein EsxQ (TB12.9) (ESAT-6 like protein 8) PPE family protein PPE46 PE family protein PE27A Secreted ESAT-6 like protein EsxR (TB10.3) (ESAT-6 like protein 9) ESAT-6 like protein EsxS PE family protein PE29 Probable transposase Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TrmU Cysteine desulfurase IscS (NIFS protein homolog) (nitrogenase metalloclusters biosynthesis protein NIFS) Conserved hypothetical protein GCN5-related N-acetyltransferase Probable electron transfer flavoprotein (alpha-subunit) FixB (alpha-ETF) (electron transfer flavoprotein large subunit) (ETFLS) Probable electron transfer flavoprotein (beta-subunit) FixA (beta-ETF) (electron transfer flavoprotein small subunit) (ETFSS) Conserved protein Conserved protein Alpha (1-_4) glucosyltransferase Conserved protein Unknown protein Possible transferase Conserved protein Probable conserved secreted protein TB22.2 Conserved hypothetical protein Conserved protein Probable enoyl-CoA hydratase EchA17 (crotonase) (unsatured acyl-CoA hydratase) (enoyl hydrase) Conserved protein Probable conserved ATP-binding protein ABC transporter Probable phosphoserine phosphatase SerB2 (PSP) (O-phosphoserine phosphohydrolase) (pspase) Probable cytochrome C oxidase polypeptide I CtaD (cytochrome AA3 subunit 1) Probable FEIII-dicitrate-binding periplasmic lipoprotein FecB Probable NADP-dependent alcohol dehydrogenase AdhC Conserved protein Hypothetical protein Rv3047c Ribonucleoside-diphosphate reductase (beta chain) NrdF2 (ribonucleotide reductase small subunit) (R2F protein) Probable monooxygenase Probable transcriptional regulatory protein (probably AsnC-family) Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) Probable NrdI protein Probable glutaredoxin electron transport component of NRDEF (glutaredoxin-like protein) NrdH Conserved hypothetical protein Possible transcriptional regulatory protein (probably TetR-family) Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) Probable short chain alcohol dehydrogenase/reductase Possible transcriptional regulatory protein (probably TetR-family) Probable cytochrome P450 136 Cyp136 Probable transcriptional regulatory protein (probably GntR-family) Probable acyl-CoA dehydrogenase FadE22 Probable ATP-dependent DNA ligase LigB (polydeoxyribonucleotide synthase [ATP]) (polynucleotide ligase [ATP]) (sealase) (DNA repair protein) (DNA joinase) Probable carbon starvation protein A homolog CstA Probable conserved integral membrane protein Multidrugs-transport integral membrane protein Mmr Probable transcriptional regulatory protein (probably DeoR-family) Conserved hypothetical protein Probable phosphoglucomutase PgmA (glucose phosphomutase) (PGM) Probable conserved transmembrane protein Probable conserved integral membrane protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved protein Conserved hypothetical protein Possible hydrolase Probable hydroxylaminobenzene mutase Hab Conserved protein Serine/threonine-protein kinase transcriptional regulatory protein PknK (protein kinase K) (STPK K) Conserved hypothetical protein Virulence-regulating transcriptional regulator VirS (AraC/XylS family) Probable monooxygenase (hydroxylase) Probable acetyl-hydrolase/esterase LipR Probable short-chain type dehydrogenase/reductase Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) Possible triacylglycerol synthase (diacylglycerol acyltransferase) Putative triacylglycerol synthase (diacylglycerol acyltransferase) Tgs4 Probable chain-fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Unknown alanine and valine rich protein Conserved protein Probable conserved integral membrane protein Hypothetical oxidoreductase Conserved hypothetical protein Hypothetical transcriptional regulatory protein Conserved hypothetical protein PE-PGRS family protein, triacylglycerol lipase LipY (esterase/lipase) (triglyceride lipase) (tributyrase) Hypothetical protein Rv3098c PemK-like protein Conserved protein Probable SSRA-binding protein SmpB Putative cell division protein FtsX (septation component-transport integral membrane protein ABC transporter) Putative cell division ATP-binding protein FtsE (septation component-transport ATP-binding protein ABC transporter) Hypothetical proline-rich protein Possible conserved transmembrane protein Probable peptide chain release factor 2 PrfB (RF-2) NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) Possible alkyldihydroxyacetonephosphate synthase AgpS (alkyl-DHAP synthase) (alkylglycerone-phosphate synthase) Hypothetical protein Rv3108 Probable molybdenum cofactor biosynthesis protein A MoaA1 Probable pterin-4-alpha-carbinolamine dehydratase MoaB1 (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin-4-a-carbinolamine dehydratase) (phenylalanine hydroxylase-stimulating protein) (PHS) (pterin carbinolamine dehydratase) (PCD) Probable molybdenum cofactor biosynthesis protein C MoaC1 Probable molybdenum cofactor biosynthesis protein D MoaD1 (molybdopterin converting factor small subunit) (molybdopterin [MPT] converting factor, subunit 1) Possible phosphatase Conserved hypothetical protein Probable transposase Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) Conserved hypothetical protein SseC1 Probable molybdenum cofactor biosynthesis protein E MoaE1 (molybdopterin converting factor large subunit) (molybdopterin [MPT] converting factor, subunit 2) Conserved hypothetical protein Probable cytochrome P450 141 Cyp141 Hypothetical protein Rv3122 Hypothetical protein Rv3123 Transcriptional regulatory protein MoaR1 PPE family protein PPE49 Hypothetical protein Rv3126c Conserved protein Conserved hypothetical protein Triacylglycerol synthase (diacylglycerol acyltransferase) Tgs1 Conserved protein Two component sensor histidine kinase DevS Two component transcriptional regulatory protein DevR (probably LuxR/UhpA-family) Universal stress protein family protein PPE family protein PPE50 PPE family protein PPE51 Conserved protein Probable monophosphatase Probable pyruvate formate lyase activating protein PflA (formate acetyltransferase activating enzyme) ([pyruvate formate-lyase] activating enzyme) Probable acyl-CoA dehydrogenase FadE24 Probable acyl-CoA dehydrogenase FadE23 Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) Hypothetical protein Rv3142c Probable response regulator PPE family protein PPE52 Probable NADH dehydrogenase I (chain A) NuoA (NADH-ubiquinone oxidoreductase chain A) Probable NADH dehydrogenase I (chain B) NuoB (NADH-ubiquinone oxidoreductase chain B) Probable NADH dehydrogenase I (chain C) NuoC (NADH-ubiquinone oxidoreductase chain C) Probable NADH dehydrogenase I (chain D) NuoD (NADH-ubiquinone oxidoreductase chain D) Probable NADH dehydrogenase I (chain E) NuoE (NADH-ubiquinone oxidoreductase chain E) Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) Probable NADH dehydrogenase I (chain G) NuoG (NADH-ubiquinone oxidoreductase chain G) Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) Probable NADH dehydrogenase I (chain I) NuoI (NADH-ubiquinone oxidoreductase chain I) Probable NADH dehydrogenase I (chain J) NuoJ (NADH-ubiquinone oxidoreductase chain J) Probable NADH dehydrogenase I (chain K) NuoK (NADH-ubiquinone oxidoreductase chain K) Probable NADH dehydrogenase I (chain L) NuoL (NADH-ubiquinone oxidoreductase chain L) Probable NADH dehydrogenase I (chain M) NUOK (NADH-ubiquinone oxidoreductase chain M) Probable NADH dehydrogenase I (chain N) NuoN (NADH-ubiquinone oxidoreductase chain N) PPE family protein PPE53 Possible transcriptional regulatory protein (probably TetR-family) Possible dioxygenase Possible integral membrane protein Possible conserved secreted protein Probable methanol dehydrogenase transcriptional regulatory protein MoxR3 Unknown protein Conserved hypothetical protein Probable transcriptional regulatory protein (probably TetR-family) Putative aminoglycoside phosphotransferase Conserved protein Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Possible non-heme haloperoxidase Hpx Hypothetical protein Rv3172c Probable transcriptional regulatory protein (probably TetR/AcrR-family) Probable short-chain dehydrogenase/reductase Possible amidase (aminohydrolase) Probable epoxide hydrolase MesT (epoxide hydratase) (arene-oxide hydratase) Possible peroxidase (non-haem peroxidase) Conserved hypothetical protein Conserved protein Hypothetical alanine rich protein Conserved protein Conserved hypothetical protein Possible transcriptional regulatory protein Probable transposase for insertion sequence element IS6110 (fragment) Probable transposase, partial Probable transposase for insertion sequence element IS6110 (fragment) Probable transposase, partial Conserved hypothetical protein Conserved hypothetical protein Hypothetical protein Rv3190c Conserved protein Probable transposase Conserved hypothetical alanine and proline-rich protein Probable conserved transmembrane protein Possible conserved secreted protein Conserved hypothetical protein Conserved hypothetical protein Unknown protein Probable conserved ATP-binding protein ABC transporter Probable transcriptional regulatory protein WhiB-like WhiB7 Probable ATP-dependent DNA helicase II UvrD2 Possible glutaredoxin protein Probable NADH pyrophosphatase NudC (NAD+ diphosphatase) (NAD+ pyrophosphatase) (NADP pyrophosphatase) Possible transmembrane cation transporter Probable ATP-dependent DNA helicase Possible ATP-dependent DNA helicase Possible lipase LipV Possible DNA-methyltransferase (modification methylase) Conserved protein Probable molybdenum cofactor biosynthesis protein MoeB1 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) Conserved protein Probable transcriptional regulatory protein (probably TetR-family) Conserved protein TB9.4 Conserved hypothetical threonine and proline rich protein Conserved protein Probable ATP-dependent RNA helicase RhlE Conserved alanine valine rich protein Possible SOJ/para-related protein Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) Probable isochorismate synthase EntC (isochorismate hydroxymutase) (enterochelin biosynthesis) Probable conserved integral membrane protein Conserved protein Transcriptional regulatory protein WhiB-like WhiB1. Contains [4FE-4S]2+ cluster Probable two component sensor kinase Biotinylated protein TB7.3 Anti-sigma factor RshA Conserved hypothetical protein Alternative RNA polymerase sigma-E factor (sigma-24) SigH (RPOE) Possible iron-regulated short-chain dehydrogenase/reductase Conserved hypothetical protein Conserved hypothetical protein GCN5-related N-acetyltransferase, phosphorylase Conserved hypothetical protein 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) Conserved hypothetical protein Possible linoleoyl-CoA desaturase (delta(6)-desaturase) Hypothetical oxidoreductase Conserved protein Polyphosphate kinase Ppk2 (polyphosphoric acid kinase) Possible triacylglycerol synthase (diacylglycerol acyltransferase) Putative triacylglycerol synthase (diacylglycerol acyltransferase) Tgs3 Hypothetical alanine arginine proline rich protein Probable conserved integral membrane transport protein Conserved protein Probable conserved integral membrane protein Probable conserved transmembrane transport protein Probable preprotein translocase SecA1 1 subunit Conserved protein Conserved hypothetical protein Unknown protein Probable conserved lipoprotein LpqB Two component sensory transduction histidine kinase MtrB Two component sensory transduction transcriptional regulatory protein MtrA Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) Possible transcriptional regulatory protein (probably TetR-family) Probable rubredoxin RubB Probable rubredoxin RubA Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauric acid omega-hydroxylase) (omega-hydroxylase) (fatty acid omega-hydroxylase) (alkane hydroxylase-rubredoxin) Possible cationic amino acid transport integral membrane protein Conserved hypothetical protein Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (phosphohexomutase) Conserved protein Probable phosphomannomutase PmmA (PMM) (phosphomannose mutase) Conserved hypothetical protein Conserved hypothetical protein Probable transcriptional regulatory protein WhiB-like WhiB2 Probable F420 biosynthesis protein FbiA Probable F420 biosynthesis protein FbiB Probable DNA methylase (modification methylase) (methyltransferase) D-alpha-D-mannose-1-phosphate guanylyltransferase ManB (D-alpha-D-heptose-1-phosphate guanylyltransferase) dTDP-RHA:a-D-GlcNAc-diphosphoryl polyprenol,a-3-L-rhamnosyl transferase WbbL1 (alpha-L-rhamnose-(1-_3)-alpha-D-GlcNAc(1-_P)-P-decaprenyl) dTDP-6-deoxy-L-lyxo-4-hexulose reductase RmlD (dTDP-rhamnose modification protein) (dTDP-rhamnose biosynthesis protein) (dTDP-rhamnose synthase) Conserved protein (CPSA-related protein) Conserved hypothetical protein Conserved protein Probable metal cation-transporting P-type ATPase C CtpC Probable conserved integral membrane protein Conserved hypothetical protein Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) Probable acyl-CoA dehydrogenase FadE25 Probable phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (air carboxylase) (AIRC) Probable phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (air carboxylase) (AIRC) Probable conserved transmembrane protein Probable conserved transmembrane protein Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (biotin--protein ligase) Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase (epsilon chain) AccE5 Conserved hypothetical protein Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) Conserved hypothetical protein Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase (alpha chain) AccA3: biotin carboxylase + biotin carboxyl carrier protein (BCCP) Alternative RNA polymerase sigma factor SigF Anti-sigma factor RsbW (sigma negative effector) Putative protein UsfY Possible transmembrane protein Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family) Conserved hypothetical protein Probable piperideine-6-carboxilic acid dehydrogenase Pcd (piperideine-6-carboxylate dehydrogenase) Conserved hypothetical protein Probable transcriptional regulatory protein (probably TetR-family) Probable ATP-dependent helicase Lhr (large helicase-related protein) Probable endonuclease VIII Nei Possible esterase lipoprotein LpqC Probable arylsulfatase AtsB (aryl-sulfate sulphohydrolase) (sulfatase) Conserved hypothetical protein Probable phosphate-transport system transcriptional regulatory protein PhoU homolog 1 PhoY1 Probable glycerol-3-phosphate dehydrogenase GlpD2 NAD(P)H quinone reductase LpdA Conserved protein Possible N-acyl-L-amino acid amidohydrolase AmiA1 (N-acyl-L-amino acid aminohydrolase) Probable amidohydrolase AmiB1 (aminohydrolase) Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) Probable phosphomannomutase PmmB (phosphomannose mutase) Probable uracil phosphoribosyltransferase Upp (UMP pyrophosphorylase) (uprtase) (UMP diphosphorylase) Acid phosphatase (acid phosphomonoesterase) (phosphomonoesterase) (glycerophosphatase) Conserved protein Conserved hypothetical protein Secreted protein antigen Probable adenosine deaminase Add (adenosine aminohydrolase) Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) Probable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) Probable succinate dehydrogenase (hydrophobic membrane anchor subunit) SdhD (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) Probable succinate dehydrogenase (flavoprotein subunit) SdhA (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) Possible toxin VapC44. Contains PIN domain Possible antitoxin VapB44 Possible methyltransferase Probable MoaD-MoaE fusion protein MoaX Probable molybdenum cofactor biosynthesis protein C 3 MoaC3 Probable transposase for insertion sequence element IS6110 (fragment) Probable transposase, partial Probable transposase fusion protein Probable alternative RNA polymerase sigma factor (fragment) SigJ Probable aminotransferase Probable penicillin-binding protein DacB1 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase) Probable sugar-transport integral membrane protein SugI Probable N-acetylglucosamine-6-phosphate deacetylase NagA (GlcNAc 6-P deacetylase) Hypothetical proline rich protein Probable transcriptional regulatory protein (probably MerR-family) Probable conserved integral membrane protein Probable tryptophanyl-tRNA synthetase TrpS (tryptophan--tRNA ligase) (TRPRS) (tryptophan translase) Conserved hypothetical protein Conserved hypothetical protein Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetylhomoserine (thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase) Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) Possible methyltransferase (methylase) PPE family protein PPE54 PE-PGRS family protein PE_PGRS49, partial PE-PGRS family protein PE_PGRS50 Conserved transmembrane protein PPE family protein PPE55 Probable transposase Probable transposase PPE family protein PPE56 Conserved hypothetical protein Possible oxidoreductase Conserved hypothetical protein Conserved hypothetical protein Probable integral membrane protein Probable bifunctional protein FolD: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase Antitoxin RelJ Toxin RelK Possible oxidoreductase Conserved hypothetical protein Conserved protein Probable ATP/GTP-binding protein Conserved hypothetical protein Conserved protein Conserved protein Probable tRNA/rRNA methylase SpoU (tRNA/rRNA methyltransferase) PE-PGRS family protein PE_PGRS51 Possible oxidoreductase Conserved protein Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) Possible triacylglycerol synthase (diacylglycerol acyltransferase) Trehalose 6-phosphate phosphatase OtsB2 (trehalose-phosphatase) (TPP) Probable enoyl-CoA hydratase EchA18 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable enoyl-CoA hydratase (fragment) EchA18.1 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable amidase AmiD (acylamidase) (acylase) Conserved hypothetical protein Halimadienyl diphosphate synthase Diterpene synthase Probable 1-deoxy-D-xylulose 5-phosphate synthase Dxs2 (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS) Probable transposase, partial Probable transposase for insertion sequence element IS6110 (fragment) Probable LYTB-related protein LytB1 Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) Possible toxin VapC46. Contains PIN domain Possible antitoxin VapB46 Possible transposase Possible transposase PE-PGRS family protein PE_PGRS52 Probable 3-hydroxyacyl-thioester dehydratase HtdY Probable conserved lipoprotein LpqD Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic acid synthase 1) Probable nucleoside hydrolase IunH (purine nucleosidase) Conserved hypothetical protein Conserved hypothetical protein Probable membrane protein Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase) Probable phytoene synthase PhyA Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate synthase): dimethylallyltransferase (prenyltransferase) (geranyl-diphosphate synthase) + geranyltranstransferase (farnesyl-diphosphate synthase) (farnesyl-pyrophosphate synthetase) (farnesyl diphosphate synthetase) (FPP synthetase) + farnesyltranstransferase (geranylgeranyl-diphosphate synthase) Possible S-adenosylmethionine-dependent methyltransferase Probable hydrolase Conserved protein Conserved hypothetical protein Hypothetical protein Rv3403c Conserved hypothetical protein Possible transcriptional regulatory protein Probable dioxygenase Possible antitoxin VapB47 Possible toxin VapC47. Contains PIN domain Cholesterol oxidase ChoD (cholesterol-O2 oxidoreductase) Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD) Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD) Conserved hypothetical protein Unknown alanine and proline rich protein Probable alternative RNA polymerase sigma-D factor SigD Conserved hypothetical protein Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster 60 kDa chaperonin 1 GroEL1 (protein CPN60-1) (GroEL protein 1) 10 kDa chaperonin GroES (protein CPN10) (protein GroES) (BCG-a heat shock protein) (10 kDa antigen) Probable O-sialoglycoprotein endopeptidase Gcp (glycoprotease) Ribosomal-protein-alanine acetyltransferase RimI (acetylating enzyme for N-terminal of ribosomal protein S18) Conserved hypothetical protein Conserved hypothetical protein Alanine racemase Alr Hypothetical protein Rv3424c PPE family protein PPE57 PPE family protein PPE58 Possible transposase Possible transposase PPE family protein PPE59 Possible transposase Possible transposase (fragment) Probable glutamate decarboxylase GadB Conserved protein Possible conserved transmembrane protein Probable conserved transmembrane protein Probable glucosamine--fructose-6-phosphate aminotransferase [isomerizing] GlmS (hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (glucosamine-6-phosphate synthase) Possible conserved transmembrane protein Conserved protein Conserved hypothetical alanine and proline rich protein Hypothetical protein Rv3440c Probable phospho-sugar mutase / MrsA protein homolog 30S ribosomal protein S9 RpsI 50S ribosomal protein L13 RplM Putative ESAT-6 like protein EsxT ESAT-6 like protein EsxU Hypothetical alanine and valine rich protein ESX conserved component EccC4. ESX-4 type VII secretion system protein. Probable membrane protein ESX conserved component EccD4. ESX-4 type VII secretion system protein. Probable integral membrane protein Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) ESX conserved component EccB4. ESX-4 type VII secretion system protein. Probable membrane protein Probable cutinase precursor Cut3 Probable cutinase precursor Cut4 Possible conserved transmembrane protein Probable conserved integral membrane protein Probable tRNA pseudouridine synthase a TruA (pseudouridylate synthase I) (pseudouridine synthase I) (uracil hydrolyase) 50S ribosomal protein L17 RplQ Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha chain) (RNA polymerase alpha subunit) (DNA-directed RNA nucleotidyltransferase) 30S ribosomal protein S4 RpsD 30S ribosomal protein S11 RpsK 30S ribosomal protein S13 RpsM 50S ribosomal protein L36 RpmJ Probable translation initiation factor if-1 InfA Conserved protein dTDP-glucose 4,6-dehydratase RmlB dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimerase) (dTDP-L-rhamnose synthetase) (thymidine diphospho-4-keto-rhamnose 3,5-epimerase) Conserved hypothetical protein Conserved hypothetical protein Possible dTDP-glucose 4,6-dehydratase Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA) Probable acetolactate synthase (large subunit) IlvB2 (AHAS) (acetohydroxy-acid synthase large subunit) (ALS) Conserved hypothetical protein Conserved protein Possible peroxidase BpoA (non-haem peroxidase) Possible transposase for insertion element IS6110 (fragment) Possible transposase for insertion element IS6110 [second part], partial Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) PE family protein PE31 PE family protein PPE60 Possible transmembrane protein Possible triacylglycerol synthase (diacylglycerol acyltransferase) Probable integral membrane protein Probable conserved membrane protein Possible exported protein Possible conserved protein CpsA Probable short-chain type dehydrogenase/reductase Conserved protein Probable esterase/lipase LipF Conserved hypothetical protein Unknown protein Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosphate synthase) (UDP-glucose-glucosephosphate glucosyltransferase) (trehalosephosphate-UDP glucosyltransferase) (trehalose-6-phosphate synthetase) (trehalose-phosphate synthase) (trehalose-phosphate synthetase) (transglucosylase) (trehalosephosphate-UDP glucosyl transferase) Unknown protein Conserved hypothetical Mce associated protein Conserved hypothetical Mce associated alanine and valine rich protein Mce-family protein Mce4F Possible Mce-family lipoprotein LprN (Mce-family lipoprotein Mce4E) Mce-family protein Mce4D Mce-family protein Mce4C Mce-family protein Mce4B Mce-family protein Mce4A Conserved integral membrane protein YrbE4B. Possible ABC transporter Conserved integral membrane protein YrbE4A. Possible ABC transporter Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenase Probable ferredoxin FdxD Probable acyl-CoA dehydrogenase FadE26 Probable acyl-CoA dehydrogenase FadE27 Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) PE-PGRS family protein PE_PGRS53 PE-PGRS family protein PE_PGRS54 Probable acetohydroxyacid synthase IlvX (acetolactate synthase) Conserved protein PE-PGRS family protein PE_PGRS55 PE-PGRS family protein PE_PGRS56, partial Probable fatty-acid-CoA ligase FadD18 (fragment) (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) PE-PGRS family protein PE_PGRS57 Fatty-acid-CoA ligase FadD19 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Possible enoyl-CoA hydratase EchA19 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Conserved hypothetical protein Probable cytochrome P450 monooxygenase 142 Cyp142 Unknown protein Possible coenzyme F420-dependent oxidoreductase Conserved hypothetical protein Possible lipid transfer protein or keto acyl-CoA thiolase Ltp4 Probable lipid carrier protein or keto acyl-CoA thiolase Ltp3 Probable conserved membrane protein Possible siderophore-binding protein Oxygenase component of 3-ketosteroid-9-alpha-hydroxylase KshA Hypothetical protein Rv3527 Unknown protein Conserved hypothetical protein Possible oxidoreductase Hypothetical protein Rv3531c PPE family protein PPE61 PPE family protein PPE62 Probable 4-hydroxy-2-oxovalerate aldolase (HOA) Probable acetaldehyde dehydrogenase (acetaldehyde dehydrogenase [acetylating]) Probable hydratase Probable dehydrogenase Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase PPE family protein PPE63 Probable lipid transfer protein or keto acyl-CoA thiolase Ltp2 Conserved protein Conserved hypothetical protein Probable acyl-CoA dehydrogenase FadE29 Probable acyl-CoA dehydrogenase FadE28 Probable cytochrome P450 125 Cyp125 Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase) Deazaflavin-dependent nitroreductase Ddn Probable short-chain type dehydrogenase/reductase Probable short-chain type dehydrogenase/reductase Probable enoyl-CoA hydratase EchA20 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Possible CoA-transferase (alpha subunit) Possible CoA-transferase (beta subunit) Possible oxidoreductase Possible electron transfer protein FdxB Conserved protein Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) Transcriptional regulatory protein (probably TetR-family) PPE family protein PPE64 Probable oxidoreductase Probable acyl-CoA dehydrogenase FadE30 Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Probable acyl-CoA dehydrogenase FadE31 Probable acyl-CoA dehydrogenase FadE32 Probable acyl-CoA dehydrogenase FadE33 Possible aspartate aminotransferase AspB (transaminase A) (ASPAT) (glutamic--oxaloacetic transaminase) (glutamic--aspartic transaminase) Arylamine N-acetyltransferase Nat (arylamine acetylase) Hypothetical protein Rv3566A Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase 3,4-DHSA dioxygenase 4,9-DHSA hydrolase Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase Reductase component of 3-ketosteroid-9-alpha-hydroxylase KshB Unknown protein Probable acyl-CoA dehydrogenase FadE34 Transcriptional regulatory protein KstR (probably TetR-family) Transcriptional regulatory protein (probably LacI-family) Possible conserved lipoprotein LppH Conserved hypothetical protein Possible arsenical pump integral membrane protein ArsB2 Possible tRNA/rRNA methyltransferase Cysteinyl-tRNA synthetase 1 CysS1 (cysteine--tRNA ligase 1) (CYSRS 1) (cysteine translase) Probable 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF (MECPS) 4-diphosphocytidyl-2C-methyl-D-erythritol synthase IspD (MEP cytidylyltransferase) (MCT) Possible transcription factor Possible conserved lipoprotein LpqE DNA repair protein RadA (DNA repair protein SMS) Conserved hypothetical protein Probable conserved membrane protein Beta-carbonic anhydrase CanB Probable adenine glycosylase MutY PE-PGRS family protein PE_PGRS58 Possible hydrolase Possible heme degrading protein MhuD Probable conserved lipoprotein LpqF Conserved hypothetical protein PE-PGRS family protein PE_PGRS59 Probable ATP-dependent protease ATP-binding subunit ClpC1 Iron-regulated H-NS-like protein Lsr2 Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) Hypothetical short protein Conserved protein Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase) Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) Conserved hypothetical alanine and leucine rich protein Probable conserved transmembrane protein rich in alanine and arginine and proline Probable conserved secreted protein 2-amino-4-hydroxy-6-hydroxymethyldihydropteridinepyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase) (7,8-dihydro-6-hydroxymethylpterin-diphosphokinase) (6-hydroxymethyl-7,8-dihydropterin diphosphokinase) Probable dihydroneopterin aldolase FolB (DHNA) Dihydropteroate synthase 1 FolP (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate diphosphorylase 1) GTP cyclohydrolase I FolE (GTP-ch-I) Membrane-bound protease FtsH (cell division protein) Hypothetical arginine and proline rich protein Conserved hypothetical protein Hypothetical protein Rv3613c ESX-1 secretion-associated protein EspD ESX-1 secretion-associated protein EspC ESX-1 secretion-associated protein A, EspA Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) Possible monooxygenase Putative ESAT-6 like protein EsxV (ESAT-6 like protein 1) Putative ESAT-6 like protein EsxW (ESAT-6 like protein 10) PPE family protein PPE65 PE family protein PE32 Probable conserved lipoprotein LpqG Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphorylase) (imp diphosphorylase) (transphosphoribosyltransferase) (guanine phosphoribosyltransferase) Possible cell cycle protein MesJ Conserved hypothetical protein Conserved protein Inorganic pyrophosphatase Ppa (pyrophosphate phospho-hydrolase) (PPASE) (inorganic diphosphatase) (diphosphate phospho-hydrolase) Probable conserved integral membrane protein Probable conserved integral membrane protein Possible transferase (possibly glycosyltransferase) Possible conserved membrane protein Conserved protein UDP-glucose 4-epimerase GalE1 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase) Probable conserved transmembrane protein Possible transposase Possible transposase Possible transposase Conserved hypothetical protein Probable transposase Possible cell filamentation protein Fic Hypothetical protein Rv3642c Hypothetical protein Rv3643 Possible DNA polymerase Probable conserved transmembrane protein DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-closing enzyme) (TOPO I) Conserved hypothetical protein Probable cold shock protein A CspA Probable helicase PE family protein PE33 Conserved hypothetical protein PE-PGRS family-related protein PE_PGRS60 PE-PGRS family-related protein PE_PGRS61 Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Possible conserved alanine rich membrane protein Probable conserved transmembrane protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Probable dipeptide-transport ATP-binding protein ABC transporter DppD Probable dipeptide-transport integral membrane protein ABC transporter DppC Probable dipeptide-transport integral membrane protein ABC transporter DppB Probable periplasmic dipeptide-binding lipoprotein DppA Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (acetate thiokinase) (acetyl-activating enzyme) (acetate--coenzyme A ligase) (acetyl-coenzyme A synthase) Possible protease Probable conserved transmembrane protein Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) Membrane-associated serine protease Conserved hypothetical protein Possible membrane-anchored thioredoxin-like protein (thiol-disulfide interchange related protein) Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)) Possible membrane protein Transcriptional regulatory protein Crp (Crp/Fnr-family) Possible hydrolase Conserved protein Conserved hypothetical protein Probable anion transporter ATPase Probable anion transporter ATPase Probable transcriptional regulatory protein WhiB-like WhiB4 Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insensitive transglycosylase (peptidoglycan TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase)] Conserved protein Probable lyase Probable cytochrome P450 137 Cyp137 Conserved hypothetical protein Anti-anti-sigma factor RsfB (anti-sigma factor antagonist) (regulator of sigma F B) Conserved protein Probable conserved transmembrane protein Probable conserved membrane protein Conserved protein Probable methanol dehydrogenase transcriptional regulatory protein MoxR2 Possible conserved membrane protein Possible conserved transmembrane protein Possible conserved membrane protein Probable glycerol kinase GlpK (ATP:glycerol 3-phosphotransferase) (glycerokinase) (GK) Possible toxin VapC48. Contains PIN domain Possible antitoxin VapB48 Conserved protein Conserved protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Glutamate--cysteine ligase GshA (gamma-glutamylcysteine synthetase) (gamma-ECS) (GCS) (gamma-glutamyl-L-cysteine synthetase) Conserved protein Conserved hypothetical proline rich protein Conserved hypothetical proline rich protein Conserved hypothetical protein Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic semialdehyde dehydrogenase) (L-aspartate-beta-semialdehyde dehydrogenase) Aspartokinase Ask (aspartate kinase) [contains: aspartokinase alpha subunit (Ask-alpha); and aspartokinase beta subunit (Ask-beta)] 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) Probable DNA polymerase III (epsilon subunit) DnaQ Possible ligase Possible cobyric acid synthase CobQ2 Conserved hypothetical protein Probable recombination protein RecR Conserved protein Conserved hypothetical protein Conserved protein Conserved protein Possible fatty acid synthase DNA polymerase III (subunit gamma/tau) DnaZ/X Conserved protein Probable conserved transmembrane protein Probable cutinase precursor [first part] Cut5a Probable cutinase [second part] Cut5b Possible oxidoreductase Possible dehydrogenase Possible oxidoreductase Probable conserved two-domain membrane protein Possible transferase Conserved hypothetical protein Possible ATP-dependent DNA ligase LigC (polydeoxyribonucleotide synthase [ATP]) (polynucleotide ligase [ATP]) (sealase) (DNA repair protein) (DNA joinase) Conserved protein Conserved hypothetical protein Putative triacylglycerol synthase (diacylglycerol acyltransferase) Tgs2 Conserved hypothetical protein Transcriptional regulatory protein (probably AraC/XylS-family) Probable conserved transmembrane protein PPE family protein PPE66 PPE family protein PPE67 Possible triacylglycerol synthase (diacylglycerol acyltransferase) Possible oxidoreductase Possible oxidoreductase Probable cation transporter P-type ATPase CtpJ Metal sensor transcriptional regulator (ArsR-SmtB family) Conserved hypothetical protein Probable PE family protein PE34 (PE family-related protein) Conserved protein Conserved hypothetical protein Conserved hypothetical protein Possible excisionase Probable integrase (fragment) Possible cytidine/deoxycytidylate deaminase Conserved protein Prephenate dehydrogenase TyrA (PDH) (hydroxyphenylpyruvate synthase) Conserved protein Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProZ Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProW Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport ATP-binding protein ABC transporter ProV Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) binding lipoprotein ProX Possible conserved membrane protein Possible acyl-CoA dehydrogenase FadE36 Possible hydrolase 19 kDa lipoprotein antigen precursor LpqH Possible two component sensor kinase TcrY Probable two component transcriptional regulatory protein TcrX Hypothetical protein Rv3766 Possible S-adenosylmethionine-dependent methyltransferase Unknown protein Hypothetical protein Rv3769 Hypothetical leucine rich protein Probable remnant of a transposase Probable remnant of a transposase Conserved hypothetical protein Probable histidinol-phosphate aminotransferase HisC2 (imidazole acetol-phosphate transaminase) (imidazolylacetolphosphate aminotransferase) Conserved protein Possible enoyl-CoA hydratase EchA21 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) Probable lipase LipE Conserved hypothetical protein Probable oxidoreductase Possible aminotransferase Probable conserved transmembrane protein alanine and leucine rich Conserved protein Probable O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter RfbE UDP-galactofuranosyl transferase GlfT1 Probable O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter RfbD Possible dTDP-glucose 4,6-dehydratase Hypothetical protein Rv3785 Unknown protein Conserved hypothetical protein Hypothetical protein Rv3788 GTRA family protein Decaprenylphosphoryl-beta-D-ribose 2'-oxidase Decaprenylphosphoryl-D-2-keto erythro pentose reductase Arabinofuranosyltransferase AftA Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) Integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase) Integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) Conserved protein Probable acyl-CoA dehydrogenase FadE35 Probable transposase Probable propionyl-CoA carboxylase beta chain 4 AccD4 (pccase) (propanoyl-CoA:carbon dioxide ligase) Polyketide synthase Pks13 Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity Probable conserved membrane protein Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) Possible arabinofuranosyltransferase AftB Decaprenylphosphoryl-5-phosphoribose (DPPR) synthase (decaprenyl-phosphate 5-phosphoribosyltransferase) Possible conserved transmembrane protein Bifunctional UDP-galactofuranosyl transferase GlfT2 UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) Exported repetitive protein precursor PirG (cell surface protein) (EXP53) Conserved hypothetical protein PE-PGRS family protein PE_PGRS62 Conserved protein Possible acyltransferase Possible acyltransferase Possible acyltransferase Possible phosphotransferase Unknown protein Unknown protein Possible conserved polyketide synthase associated protein PapA2 Probable conserved integral membrane protein Conserved hypothetical protein Conserved integral membrane transport protein MmpL8 Conserved polyketide synthase associated protein PapA1 Polyketide synthase Pks2 Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Possible transposase Possible resolvase Probable dehydrogenase Transcriptional regulatory protein (probably TetR-family) Hypothetical protein Rv3831 Conserved protein Transcriptional regulatory protein (probably AraC-family) SERYL-tRNA synthetase SerS (serine--tRNA ligase) (SERRS) (serine translase) Conserved membrane protein Conserved hypothetical protein Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) Prephenate dehydratase PheA Conserved hypothetical protein Possible transcriptional regulatory protein Bacterioferritin BfrB Probable glycerophosphoryl diester phosphodiesterase GlpQ1 (glycerophosphodiester phosphodiesterase) Probable conserved transmembrane protein Possible transposase Hypothetical protein Rv3845 Superoxide dismutase [FE] SodA Hypothetical protein Rv3847 Probable conserved transmembrane protein ESX-1 transcriptional regulatory protein EspR Conserved protein Possible membrane protein Possible histone-like protein Hns Regulator of RNase E activity a RraA Monooxygenase EthA Transcriptional regulatory repressor protein (TetR-family) EthR Conserved hypothetical protein Possible membrane protein Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (glutamate synthase (NADH)) (GLTS beta chain) (NADPH-GOGAT) Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (glutamate synthase (NADH))(NADPH-GOGAT) Conserved protein Hypothetical protein Rv3861 Possible transcriptional regulatory protein WhiB-like WhiB6 Unknown alanine rich protein ESX-1 secretion-associated protein EspE ESX-1 secretion-associated protein EspF ESX-1 secretion-associated protein EspG1 ESX-1 secretion-associated protein EspH ESX conserved component EccA1. ESX-1 type VII secretion system protein ESX conserved component EccB1. ESX-1 type VII secretion system protein. Possible membrane protein ESX conserved component EccCa1. ESX-1 type VII secretion system protein. Possible transmembrane protein ESX conserved component EccCb1. ESX-1 type VII secretion system protein PE family-related protein PE35 PPE family protein PPE68 10 kDa culture filtrate antigen EsxB (LHP) (CFP10) 6 kDa early secretory antigenic target EsxA (ESAT-6) ESX-1 secretion-associated protein EspI. Conserved proline and alanine rich protein ESX conserved component EccD1. ESX-1 type VII secretion system protein. Probable transmembrane protein ESX-1 secretion-associated protein EspJ. Conserved alanine rich protein ESX-1 secretion-associated protein EspK. Alanine and proline rich protein ESX-1 secretion-associated protein EspL Secreted ESX-1 substrate protein B, EspB. Conserved alanine and glycine rich protein ESX conserved component EccE1. ESX-1 type VII secretion system protein. Possible membrane protein Membrane-anchored mycosin MycP1 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-1) ESX conserved component EccA2. ESX-2 type VII secretion system protein. Probable CbxX/CfqX family protein ESX conserved component EccE2. ESX-2 type VII secretion system protein. Possible membrane protein Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-2) ESX conserved component EccD2. ESX-2 type VII secretion system protein. Probable transmembrane protein Probable conserved membrane protein ESX-2 secretion-associated protein EspG2 ESAT-6 like protein EsxC (ESAT-6 like protein 11) Possible ESAT-6 like protein EsxD PPE family protein PPE69 PE family protein PE36 ESX conserved component EccC2. ESX-2 type VII secretion system protein. Possible membrane protein ESX conserved component EccB2. ESX-2 type VII secretion system protein. Probable membrane protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical protein Conserved hypothetical alanine rich protein Possible membrane protein Hypothetical protein Rv3902c Hypothetical alanine and proline rich protein Putative ESAT-6 like protein EsxE (hypothetical alanine rich protein) (ESAT-6 like protein 12) Putative ESAT-6 like protein EsxF (hypothetical alanine and glycine rich protein) (ESAT-6 like protein 13) Conserved hypothetical protein Probable poly(A) polymerase PcnA (polynucleotide adenylyltransferase) (NTP polymerase) (RNA adenylating enzyme) (poly(A) polymerase) Possible mutator protein MutT4 Conserved protein Probable conserved transmembrane protein Possible alternative RNA polymerase sigma factor SigM Hypothetical alanine rich protein Probable thioredoxin reductase TrxB2 (TRXR) (TR) Thioredoxin TrxC (TRX) (MPT46) Probable peptidoglycan hydrolase Conserved hypothetical protein Probable chromosome partitioning protein ParB Probable chromosome partitioning protein ParA Probable glucose-inhibited division protein B Gid Conserved protein similar to jag protein Probable conserved transmembrane protein Possible hemolysin Ribonuclease P protein component RnpA (RNaseP protein) (RNase P protein) (protein C5) 50S ribosomal protein L34 RpmH