content_image/887000.jpg content_image/886999.jpg content_image/886998.jpg content_image/887004.jpg content_image/887003.jpg content_image/887002.jpg content_image/887001.jpg
Derivative [HM-1] having a structure shown below. The purity was 92% (as determined by a liquid chromatography method). 

<img src='content_image/887000.jpg'>

Synthesis of(MM-1): 

Gram of Hydroxymethyl Group-Containing Phenol Derivative [HM-1] obtained in Synthesis Example above was added to 1 liter of methanol and dissolved with stirring under heating. Subsequently, 1 ml of concentrated sulfuric acid was added to the resulting solution, and the mixture was refluxed under heating for 12 hours. After the completion ofreaction, the reaction solution was cooled, and 2 g of potassium car› bonate was added thereto. This mixture was sufficiently con› centrated, and 300 ml of ethyl acetate was added thereto. The resulting solution was washed with water and then concen› trated to dryness to obtain 22 g of a white solid ofMethoxym› ethyl Group-Containing Phenol Derivative [MM-1] having a structure shown below. The purity thereof was 90% ( as deter- mined by a liquid chromatography method). 

<img src='content_image/886999.jpg'>

Furthermore, the phenol derivatives shown below were synthesized in the same manner. 

<img src='content_image/886998.jpg'>

<img src='content_image/887004.jpg'>

<img src='content_image/887003.jpg'>

<img src='content_image/887002.jpg'>

<img src='content_image/887001.jpg'>

-continued 

