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## R&D PIPELINE 

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Compounds in Exploratory Development  are in preclinical or early clinical development. Full Development  compounds are investigational drugs that are in later-stage clinical development or have been submitted to regulatory agencies for approval. 

Pipeline data as of February 15, 2013 

## OuR PIPElINE IS ONE OF THE STRONGEST IN THE INDuSTRy. 

The Ongoing Development  for Approved Medicines  table includes compounds that have been approved in at least one major market and are in development for additional indications or formulations that may benefit patients. 

registrational programs 

* Forxiga  is not approved in the U.S. 

