Puma Biotechnology, Inc.  is a development stage biopharmaceutical company that acquires and develops innovative products for the treatment of various forms of cancer. We focus on in-licensing drug candidates that are undergoing or have already completed initial clinical testing for the treatment of cancer and then further develop those drug candidates for commercial use. 

Our lead drug candidate PB272 (neratinib (oral))  is a potent irreversible tyrosine kinase inhibitor, which we are developing across a broad range of tumors and indications. We are initially focused on developing PB272 for the treatment of patients with HER2-positive metastatic breast cancer and for patients with non-small cell lung cancer, breast cancer and other solid tumors that have a HER2 mutation. 

