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## New Framework for Accelerating R&D 

Controlling uncertainties while making efficient and early decisions is critical to assessing new R&D challenges. 

We have introduced a multi-track process called FASTEN, under which R&D projects are managed along one of three different tracks: New-standard Track, Fast Track or Ex. Track. The aim of this process is to accelerate achiev- ing the Proof of Concept (POC) for R&D projects from the preclinical late stage of research to the early stage of clinical development so that a greater number of promis- ing drug candidates end up entering late-stage clinical development. The process also aims to reduce the overall time from R&D inception to marketing launch. 

## faST TraCk 

Prioritized projects are designated on the Fast Track. We concentrate resources on them from an early stage in drug development in an attempt to reduce the total time spent in R&D and achieve market launch as early as possible. 

## NEw-STaNdard TraCk 

Most projects are located on this new-standard track, where the aim is to minimize the time and costs involved from the identification of the drug candidate to the POC. In this way, we increase the number of candidate projects at the early R&D stages without changing the total amount of management resources invested. 

## Ex. TraCk 

This track is used to accommodate particularly unique or challenging projects. The aim is to demonstrate POC efficiently, making flexible use of external resources. 

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