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## Note 12 PROPERTY, PLANT AND EQUIPMENT 

Property, plant and equipment includes: 

<img src='content_image/141631.jpg'>

Depreciation expense was $382 million in 2012, $448 million in 2011 and $473 million in 2010. 

## $^{ }$Note 13 GOODWILL AND OTHER INTANGIBLE ASSETS 

Changes in the carrying amount of goodwill were as follows: 

<img src='content_image/141632.jpg'>

$^{ }$Other includes an out-of-period adjustment to correct the purchase price allocation for the September 2009 Medarex acquisition and a $24 million contingent milestone payment from a prior acquisition. The Medarex purchase price adjustment decreased other intangible assets by $98 million and increased deferred tax assets by $34 million and goodwill by $64 million. The effect of this adjustment was not material for the current or any prior periods. 

$^{ }$Other intangible assets include: 

<img src='content_image/141638.jpg'>

$^{ }$Changes in other intangible assets were as follows: 

<img src='content_image/141639.jpg'>

Annual amortization expense of other intangible assets is expected to be approximately $850 million in 2013, $850 million in 2014, $750 million in 2015, $750 million in 2016, $700 million in 2017 and $4,210 million thereafter. 

