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# c19) United States 

# c12) Patent Application Publication Labib et al. 

# (54) CELLULOSE AND ACRYLIC BASED POLYMERS AND THE USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES 

(76) Inventors: Mohamed E. Labib, Princeton, NJ (US); Robert F. Rando, Annandale, NJ (US) 

Correspondence Address: SCULLY SCOTT MURPHY & PRESSER, PC 400 GARDEN CITY PLAZA SUITE 300 GARDEN CITY, NY 11530 (US) 

(21) Appl. No.: 11/592,479 

(22) Filed: Nov. 3, 2006 

(63) Continuation-in-part of application No. PCT/US05/ 01529, filed on Jan. 12, 2005, which is a continuation› in-part of application No. 10/837,153, filed on May 3, 2004. 

## Related U.S. Application Data 

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US 20070148124Al 

# c10) Pub. No.: US 2007/0148124 Al 

# (43) Pub. Date: Jun. 28, 2007 

(51) Int. Cl. 

<img src='content_image/938852.jpg'>

(52) U.S. Cl. ................... 424/78.18; 424/78.01; 525/54.2 

## (57) ABSTRACT 

The present invention provides methods for the treatment or prevention of a viral, bacterial, or fungal infection using an anionic cellulose- or acrylic-based polymer, a prodrug thereof, or a pharmaceutically acceptable salt of said anionic cellulose based polymer or acrylic based polymer or prodrug of either. The present invention also provides pharmaceuti› cal compositions comprising an anionic cellulose or acrylic based polymer, a prodrug thereof, or a pharmaceutically acceptable salt of said anionic cellulose-based polymer or prodrug. The present invention further provides combination therapies for the treatment or prevention of a viral, bacterial, or fungal infection using an anionic cellulose or acrylic› based polymer, a prodrug thereof, or a pharmaceutically acceptable salt of said anionic cellulose based or acrylic based polymer or prodrug of either and one or more anti› infective agents. 

## Publication Classification 

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