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Under ice cooling, 1.04 g oftetramethylene sulfoxide was added dropwise to a mixture of 4.91 g of triphenylamine, 9.81 g of Eaton reagent (Tokyo Chemical Industry Co., Ltd., the same hereinafter) and 10 g of dichloromethane. The contents were stirred under ice cooling for 1 hour and at room temperature for a further 4 hours for aging. The reaction mixture was quenched by adding 40 g of water, combined with 4.14 g of Sulfonate 1 and 30 g of dichlo› romethane, and stirred, after which the organic layer was taken out. The organic layer was washed 5 times with 30 g of water, from which dichloromethane was removed by vacuum concentration. The procedure including adding 30 g of disopropyl ether to the concentrate, stirring for 5 minutes, and removing the supernatant was repeated 5 times. This was followed by vacuum concentration. The thus precipi› tated solid was dried under reduced pressure, obtaining 4.93 g of the desired compound PAG-1 in solid form (yield 67%). Spectral data of PAG-1 are shown below. 

IR (D-ATR): v=3483, 3068, 2908, 2853, 1754, 1580, 1492, 1453, 1423, 1371, 1335, 1264, 1245, 1216, 1182, 1164, 1103, 1087, 1032, 992, 916, 867, 824, 757, 732, 697, 676, 640, 612, 598, 582 cm- 1 

$^{1}$H-NMR (500 MHz, DMSO-d$_{6}$ ): o=l.58-1.73 (6H, m), 1.74-1.91 (6H, m), 1.96 (3H, s), 2.23 (2H, m), 2.35 (2H, m), 3.59 (2H, m), 3.87 (2H, m), 5.93 (lH, m), 6.91 (2H, m), 7.18 (4H, m), 7.24 (2H, m), 7.42 (4H, m), 7.69 (2H, m) ppm 

$^{19}$F-NMR (500 MHz, DMSO-d$_{6}$ ): o=-119.5 (IF, m), -113.5 (IF, m), -72.4 (3F, m) ppm 

TOF-MS (MALDI): POSITIVE M+ 332 (corresponding to C$_{22}$H$_{22}$NS+) 

NEGATIVE M- 391 (corresponding to C$_{14}$H$_{16}$F$_{5}$ 0$_{5}$ S-) 

Synthesis of PAG-2 

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PAG-1 

Under ice cooling, 1.04 g oftetramethylene sulfoxide was added dropwise to a mixture of 6.13 g of triphenylamine, 12.27 g of Eaton reagent and 12.5 g of dichloromethane. The contents were stirred under ice cooling for 1 hour and at room temperature for a further 4 hours for aging. The reaction mixture was quenched by adding 60 g of water, combined with 6.88 g of Sulfonate 2 and 40 g of dichlo› romethane, and stirred, after which the organic layer was taken out. The organic layer was washed 5 times with 40 g of water, from which dichloromethane was removed by vacuum concentration. The concentrate was purified by silica gel chromatography, obtaining 3.50 g of the desired compound PAG-2 in solid form (yield 46% ). Spectral data of PAG-2 are shown below. 

IR (D-ATR): v=3456, 3032, 2908, 2852, 1760, 1580, 1492, 1453, 1408, 1330, 1299, 1237, 1219, 1196, 1127, 1060, 1041, 1018, 970, 824, 758, 729, 697, 650, 616, 594 cm- 1 

$^{1}$H-NMR (500 MHz, DMSO-d$_{6}$ ): o=l.58-1.70 (6H, m), 1.83 (6H, d), 1.95 (3H, s), 2.23 (2H, m), 2.34 (2H, m), 3.55 (2H, s), 3.59 (2H, m), 3.88 (2H, m), 6.91 (2H, m), 7.17 (4H, m), 7.24 (2H, m), 7.42 (4H, m), 7.70 (2H, m) ppm 

$^{19}$F-NMR (500 MHz, DMSO-d$_{6}$ ): o=-72.3 (6F, s) ppm TOF-MS (MALDI): POSITIVE M+ 332 (corresponding to C$_{22}$H$_{22}$NS+) 

NEGATIVE M- 423 (corresponding to C$_{15}$H$_{17}$F$_{6}$ 0$_{5}$ S-) 

Synthesis of PAG-3 

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PAG-2 

