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## LETTER CONTINUED FROM P.08 

## Commercializing Protons 

PROTON THERAPY IS ON ITS WAY TO BECOMING AN IMPORTANT TOOL FOR TREATING CANCER. WHILE MARKET development was slow in fiscal 2013, we passed a major clinical milestone and saw several new business opportunities arise as new groups pressed forward with establishing clinical capability around the world. 

We initiated our investment in this exciting technology in 2007 in response to demand from clinicians who saw potential in protons to improve treatment precision and outcomes, particularly in pediatric cases. During 2013 we installed our first commercial ProBeam™ system at Scripps Proton Therapy Center in San Diego and filed an application for 510(k) clearance with the U.S. Food and Drug Administration. We hope to see patient treatments begin at Scripps early in 2014. We are working towards installing systems in St. Petersburg, Russia and Riyadh, Saudi Arabia, and we are under contract to supply systems for centers planned in the United States in Baltimore, Atlanta and Dallas. 

Varian is uniquely able to capitalize on decades of technological development and clinical expertise in radiation oncology to offer intensity modulated proton therapy and proton treatment planning as well as image-guidance and motion management technology. In this way, we offer an advanced and cost-effective proton treatment capability. We are also focused on driving down the cost of this technology with more compact designs for two- and one-room systems. 

LETTER CONTINUES ON P.12 

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