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# United States Patent [191 

# Nicholson et al. 

# [54] METAL-LIGAND COMPLEX CATALYZED PROCESSES 

[75) Inventors: James Clair Nicholson. Saint Albans; David Robert Bryant, South Charleston; James Russell Nelson. Charleston, all of W. Va. 

[73] Assignee: Union Carbide Chemicals & Plastics Technology Corporation. Danbury. Conn. 

[21] Appl. No.: 757,744 

[22] Filed: Nov. 26, l!J96 

[51) Int. Cl. 6 ..................................................... C07C 45/50 

[52) U.S. Cl . ............................................. 568/454; 568/451 

[58] Field of Search ...................................... 568/451. 454 

## [56] References Cited 

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## U.S. PlXfENT DOCUMENTS 

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# [111 Patent Number: 5,744,650 

# [451 Date of Patent: Apr. 28, 1998 

Primary Examiner-Gary Geist 

Assistant Examiner-Sreeni Padmanabhan 

Attome_… Agent, or Firm-Gerald L. Coon 

## [57] ABSTRACT 

This invention relates to a process which comprises reacting one or more reactants in the presence of a metal› organopolyphosphite ligand complex catalyst and optionally free organopolyphosphite ligand to produce a reaction prod› uct fluid comprising one or more products. wherein said process is conducted at (a) a carbon monoxide partial pressure such that reaction rate increases as carbon monox› ide partial pressure decreases and reaction rate decreases as carbon monoxide partial pressure increases and which is sufficient to prevent and/or lessen deactivation of the metal› organopolyphosphite ligand complex catalyst and (b) a temperature such that the temperature difference between reaction product fluid temperature and inlet coolant tem› perature is sufficient to prevent and/or lessen cycling of carbon monoxide partial pressure. hydrogen partial pressure. total reaction pressure. reaction rate and/or temperature during said process. 

US005744650A 

## 20 Claims, 1 Drawing Sheet 

