In 1957, American biologists Kenneth Schwarz and Walter Mertz discovered GTF in pig kidneys. They later showed that this complex of vitamins, amino acids, and trivalent chromium plays a key role in activating insulin receptors and also reduces blood sugar levels.
早在一九五七年，美國生物學者史沃茲、莫滋等人，就在豬腎中發現耐糖因子，隨後證實這種維生素、胺基酸、三價鉻的複合物，是活化胰島素受體的必要分子，它具有降低血糖的協同作用，其中三價鉻更是關鍵。