If these symptoms are left untreated for an extended period, they can cause severe depression which can take the form of unresponsiveness to one's environment, a feeling of helplessness, alienation, self-abasement or feelings of guilt. The results can be startling psychoses, including schizophrenia and personality disorders. Suicide often becomes the last resort of these victims of long-term depression.
這些身心癥狀若長期累積，最後會導致頑強的抑鬱狀態，形成冷漠、無助、孤立、自我形象貶損、罪惡性冥想等癥狀，結果可能造成驚人的心理損失，例如精神分裂、人格異常；自殺，也常被這些長期抑鬱的病患視為最後的出路。