The earliest record of dengue fever in Taiwan dates from 1870. In 1942 some five million people, representing 83 % of the total population of the time, were infected by a dengue epidemic.
登革熱在台灣最早的出現記錄是一八七○年；一九四二年時，曾釀成全台五百萬人感染，疫情嚴重，佔當時人口的六分之五。