Even more tragic was the fact that because the epidemics had been introduced from Europe, the indigenous peoples of the Americas, who were the only ones affected by them, considered them to be heaven's wrath. Believing that their gods and customs provided no protection, they rejected their traditions. America's glorious ancient civilizations were thus completely annihilated.
更悲慘的是，由於疫病只戕害美洲原住民，卻放過歐洲的侵略者，結果連原住民也認為這是「天譴」、認為自己的神祇和習俗不能提供庇佑，憤而棄絕傳統，曾經有著輝煌歷史的美洲古文明，就這樣被徹底滅絕。