Late-onset Pompe disease may occur at any time from childhood to old age, and progresses more slowly. The course of the disease in different patients varies widely, with some suffering only muscle weakness, while others need a wheelchair or respirator.
「晚發型」則從兒童時期到晚年都可能發生，其惡化較慢，個別差異很大，有人只是肌肉無力，有人則需要輪椅或呼吸器。