Hu Wu-liang, a pediatrician at National Taiwan University Hospital (NTUH) and president of the Taiwan Human Genetics Society, notes that unlike viral or bacterial infections, genetic abnormalities occur very infrequently; this is why many rare disorders are genetic in nature. Many genetic diseases are metabolic disorders.
罕見疾病多為遺傳性疾病，人類遺傳學會理事長胡務亮指出，遺傳基因變異不同於病毒、細菌感染，機率非常之低，這是罕見疾病之所以多為遺傳疾病的原因。