Symptoms of infantile Pompe disease include severe muscle weakness, enlarged heart, swollen tongue, enlarged internal organs, and difficulty in breathing. Death usually occurs within one year after symptoms appear, with the immediate cause being cardiopulmonary failure.
龐貝氏症兒的症狀有：嚴重肌肉無力、心臟肥大、舌頭肥大、肝臟肥大、呼吸困難，常在發病第一年死於心臟呼吸衰竭。