After nearly seven years of administrative work, Chang hoped to return to his beloved research. In 2006 he was accepted as a research fellow at Academia Sinica's Genomics Research Center.
做了將近 7 年行政工作之後，張子文希望能回頭做他最熱愛的研究工作，2006 年獲聘為中研院「基因體研究中心」研究員。