Because many older pregnant women used artificial reproductive technology to get pregnant, they more frequently have twins and multiple births. When they do carry more than one fetus, it puts an additional burden on the mother's heart and lungs, so that they suffer from high blood pressure and other medical conditions at a rate several times higher than other pregnant mothers of advanced age.
此外，由於許多高齡產婦是借助人工生殖科技受孕，懷有雙胎胎甚至多胞胎的比例極高，母體的心肺負擔更為沈重，併發高血壓等內科疾病的機率，也會比其他熟齡準媽媽高出數倍。