Lou Ru-pin indicates that since the gradual emergence of medical treatment for depression in the 1950's, drugs used today in the treatment of depression have minimal side effects.
陸汝斌指出，從一九五○年代就逐漸出現治療憂鬱症的藥物，目前，抗憂鬱症藥物的副作用已可降到非常低，像「百憂解」就被視為正常人都可以吃的「精神維他命」。