Some foreign manufacturers have complained that these compulsory reductions are too large, and they will no longer be able to meet costs; they do not rule out withdrawing from the Taiwan market or switching to the self-paying market. Coincidentally, at the same time a story emerged that a hospital in Chiayi had been sold fake high-blood-pressure meds, raising concerns about how to balance cost reductions with safety.
面對健保局的強勢降價，部分外商藥廠一度揚言，基於調幅過大、經營不敷成本，不排除退出台灣市場或改走自費市場，致使民眾將面臨被迫換藥的衝擊；此時，又傳出嘉義華濟醫院誤買高血壓假藥事件，藥品售價與安全如何兼顧？