Both James and his older brother Michael Chang are old hands in the biotech industry: James held a senior position at Allergan Pharmaceuticals before coming to TaiMed and Michael is the co-founder of San Diego, California's Optimer Pharmaceuticals.
他的兄長張念慈是加州聖地牙哥「浩鼎生技」（Optimer）的創辦人，兄弟倆都是生技界的老手。