Although semi-synthetic versions of taxol have already reached the market in Germany and the USA, there is still a need to harvest large quantities of Pacific yew bark. This means that the crisis of survival for the Pacific yew has not passed. Furthermore, since taxol cannot as yet be reliably manufactured in large quantities, the supply of injectable taxol falls far short of demand, and that its price is very high.
雖然在德國、美國已有半合成的紫杉醇上市，但仍須取用大量紫杉樹皮，不僅紫杉的生存危機未止，紫杉醇無法穩定、多量生產，也造成紫杉醇針劑供不應求、費用高昂。