Yin stresses that if more than four and a half hours pass before the patient reaches the hospital, the same treatment will be much less effective. And after six hours, the use of thrombolytic agents isn't recommended. "That's because brain cells are tricky and fragile.
尹居浩強調，隨著時間流失，若送院時間超過 4.5 小時，效果就遞減；若超過 6 小時，就不建議使用血栓溶解劑，「因為腦細胞搞怪又脆弱，本來在缺血狀態，突然一下血流暢通，反而禁不起這麼大刺激，可能造成腦出血的副作用。」