He was sent by Emperor Han Ming-ti (reigned A.D. 58-76) to the Western Region (central Asia). There he conquered fifty nations, and caused the peoples of the area to give tribute to the Han emperor.
漢明帝時，奉命平定擾攘的西域，使西域五十餘國紛紛臣服，每年定期向漢朝納貢，建立漢朝與西域各國間的友好關係。