On the contrary, in the late 1980s the incidence of active tuberculosis cases and the mortality rate began to rise once more. The appearance of drug-resistant forms of M. tuberculosis has increased the difficulty of treating tuberculosis.
相反地，在一九八○年代末期，結核病發病率和死亡率又再度揚升，棘手的抗藥性結核菌種的出現，更增加了結核病治療的難度。