The first "successful" use of gene therapy occurred in 1990, at the US National Health Institute, when it was applied in a case of severe combined immunodeficiency.
一九九○年，美國國家衛生院完成了人類醫學史上第一個基因治療的「成功」案例，首次案例是治療一種嚴重聯合免疫缺乏症。