The first phase of human trials follows the completion of animal testing. Its objective is to understand the drug's toxicity in humans, and looks at biochemical and physiological phenomena such as absorption, distribution, metabolism, excretion, and tolerability.
第一期臨床試驗是指新開發藥物完成動物實驗後，首次以人體為對象的試驗，其目的在瞭解該藥物對人體的毒性，以及吸收、分佈、代謝、排除、忍受度等生化現象與生理反應。