The main argument of the book draws on recent discoveries in neurobiology and microbiology. It argues that "endorphins" are the key determinants of health. Endorphins are a type of hormone secreted in the brain; they are similar to morphine.
《腦內革命》的主要論點是依據現代醫學在腦生理學和分子生理學上的新發現，指出「腦內嗎啡」為主宰人體健康的關鍵。