Who were the "Big Four" of Thrash Metal?
Anthrax, Metallica, Megadeth, and Slayer
Below is an instruction that describes a task, paired with an input that provides further context. Write a response that appropriately completes the request.
### Instruction: Who were the "Big Four" of Thrash Metal?
### Input: 
### Response: Anthrax, Metallica, Megadeth, and Slayer