ACT_SITE 257; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 336; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 446; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 450; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 479; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 483; /evidence="ECO:0000250|UniProtKB:Q38860"