ACT_SITE 85; /evidence="ECO:0000250|UniProtKB:Q96DC9"; ACT_SITE 88; /note="Nucleophile"; /evidence="ECO:0000250|UniProtKB:Q96DC9"; ACT_SITE 245; /evidence="ECO:0000250|UniProtKB:Q96FW1"; ACT_SITE 267; /evidence="ECO:0000250|UniProtKB:Q96DC9"