ACT_SITE 64; /note="Nucleophile"; /evidence="ECO:0000250"; ACT_SITE 67; /note="Nucleophile"; /evidence="ECO:0000250"; ACT_SITE 183; /note="Nucleophile"; /evidence="ECO:0000250"; ACT_SITE 186; /note="Nucleophile"; /evidence="ECO:0000250"