ACT_SITE 42; /note="Nucleophile"; /evidence="ECO:0000250|UniProtKB:Q96AP4"; ACT_SITE 165; /note="Proton acceptor"; /evidence="ECO:0000250|UniProtKB:Q96AP4"; ACT_SITE 183; /evidence="ECO:0000250|UniProtKB:Q99K23"