ACT_SITE 158; /evidence="ECO:0000250|UniProtKB:Q96FW1"; ACT_SITE 161; /note="Nucleophile"; /evidence="ECO:0000250|UniProtKB:Q5VVQ6"; ACT_SITE 267; /evidence="ECO:0000250|UniProtKB:Q5VVQ6"; ACT_SITE 341; /evidence="ECO:0000250|UniProtKB:Q96FW1"