ACT_SITE 466; /evidence="ECO:0000255|PROSITE-ProRule:PRU01352, ECO:0000305|PubMed:28781080"; ACT_SITE 542; /evidence="ECO:0000255|PROSITE-ProRule:PRU01352, ECO:0000305|PubMed:28781080"; ACT_SITE 546; /evidence="ECO:0000255|PROSITE-ProRule:PRU01352"