ACT_SITE 102; /note="Nucleophile"; /evidence="ECO:0000250"; ACT_SITE 105; /note="Nucleophile"; /evidence="ECO:0000250"; ACT_SITE 444; /note="Nucleophile"; /evidence="ECO:0000250"; ACT_SITE 447; /note="Nucleophile"; /evidence="ECO:0000250"