ACT_SITE 258; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 337; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 421; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 425; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 454; /evidence="ECO:0000250|UniProtKB:Q38860"; ACT_SITE 458; /evidence="ECO:0000250|UniProtKB:Q38860"