ACT_SITE 101; /note="Nucleophile"; /evidence="ECO:0000250|UniProtKB:P37528"; ACT_SITE 208; /note="Charge relay system"; /evidence="ECO:0000250|UniProtKB:P37528"; ACT_SITE 210; /note="Charge relay system"; /evidence="ECO:0000250|UniProtKB:P37528"