ACT_SITE 237; /note="Nucleophile"; /evidence="ECO:0000255|PROSITE-ProRule:PRU01284"; ACT_SITE 290; /note="Proton acceptor"; /evidence="ECO:0000255|PROSITE-ProRule:PRU01284"; ACT_SITE 302; /evidence="ECO:0000255|PROSITE-ProRule:PRU01284"