There are few guitars as iconic as the Fender Stratocaster.  This guitar was originally developed in the early 1950's and has taken the world by storm.  To name a few very notable Stratocaster players the list would have to include Jimi Hendrix, Stevie Ray Vaughn, Eric Clapton, John Mayer, Yngwie Malmsteen, Buddy Guy and John Frusciante.  As you can see this list spans many genres and speaks to the flexibility of this instrument.