The Popelogan River is a tributary of the Eastern shore Upsalquitch River, flowing particularly through the Addington Parish, in Restigouche County, in the Northwest the New Brunswick, in Canada.

In his course to the south, the Popelogan river flows through a valley increasingly deep in the mountainous terrain. Its main tributaries are the Gordon Brook and the "Lake Popelogan Branch" which supplies at Popelogan Lake. A forest road serves the upper part of the river, from Popelogan Depot.