Unione Sportiva Sassuolo Calcio, commonly referred to as Sassuolo (Italian pronunciation: [sasˈswɔːlo]), is an Italian football club based in Sassuolo, Emilia-Romagna. Their colours are black and green, hence the nickname Neroverdi (literally "black and green", in Italian).

Sassuolo have played in Serie A since the 2013–14 season, joining a select group of teams playing in the Serie A but not belonging to a provincial capital city: U.S. Savoia 1908 (Torre Annunziata), Empoli, Legnano, Pro Patria (Busto Arsizio), Carpi and Casale.