Chenghua Gu
Gu earned her Ph.D. at Cornell Medical School. She then joined the lab of David Ginty at the Johns Hopkins University School of Medicine where she studied the role of semaphorin signaling in vascular development. Gu's research focuses on the development of the blood-brain barrier and its interaction with neuronal networks. She uses experimental techniques such as Two-photon excitation microscopy, mouse genetics and computational models to study neurovascular coupling, the regulation of blood flow by changes in neuronal activity, and vascular patterning. Her laboratory has recently published on the importance of the inhibition of transcytosis for maintaining blood-brain barrier integrity and how the mechanisms regulating transcytosis levels could be manipulated to aid the entry of therapeutics into the central nervous system.
Research
Chenghua Gu is a Professor of Neurobiology at the Harvard Medical School where her research focuses on the Blood–brain barrier.