2021–22 Stony Brook Seawolves women's basketball team
Stony Brook made the NCAA Tournament for the first time in 2021, defeating Maine 64–60 in the America East championship game. Stony Brook entered the conference tournament as the two seed, upsetting Maine who was the one seed. The two teams were supposed to meet in the 2020 America East championship game, with Stony Brook as the one seed and Maine as the two seed, but the game was cancelled due to the COVID-19 pandemic. Stony Brook was 28–3 that season and was named America East champions as the highest seed remaining in the tournament. In the 2021 NCAA Division I Women's Basketball Tournament, Stony Brook was a 14 seed and faced 3-seed Arizona in the first round. Stony Brook lost 79–44. Head coach Caroline McCombs left to become the head coach of George Washington after the season ended. !colspan=12 style=| Exhibition
!colspan=12 style=| Non-conference regular season
!colspan=12 style=| America East regular season
Source
Previous season
The 2021–22 Stony Brook Seawolves women's basketball team represents Stony Brook University in the 2021–22 NCAA Division I women's basketball season.