Stephan A. Mayer
Mayer originated the concept of ultra-early hemostatic therapy for intracerebral hemorrhage (ICH), and served as principal investigator of a multinational multicenter testing program evaluating recombinant factor VIIa for this indication. Mayer predominantly uses invasive brain multimodality monitoring to guide therapy and increase situational awareness in the treatment of coma. Other contributions to the field of neurocritical care that Mayer and colleagues have introduced include the Bedside Shivering Assessment Scale and the Columbia Anti-Shivering Protocol, both of which are used to facilitate therapeutic temperature modulation throughout the world; the Modified Fisher Scale, the most widely-used scale to assess vasospasm risk after subarachnoid hemorrhage; and the concept of “CTA-for-All” for stroke imaging, to increase the likelihood of successful endovascular reperfusion. Mayer's work in helping victims of severe brain injury has been featured in two books, "Back from the Brink" by Edward Sylvester and "Cheating Death" by CNN medical correspondent Sanjay Gupta.
Research and career
Mayer is most noted for his research in subarachnoid and intracerebral hemorrhage, acute ischemic stroke, cardiac arrest, coma, status epilepticus, brain multimodality monitoring, therapeutic temperature modulation, and outcomes after severe brain injury.