### Comment:
&gt; Also it did not occur too frequently in the patients in the two phase 3s 
  
 What was the trial duration? A lot of shit doesn't show up in just a few months, what was the N? 
  


### REPLY:
Trial duration 1 year total. 9-11% of serious ADEs on 200-400mg doses. They also had 4-5% occurrence of DKA. The original study was 24 weeks following 6 week insulin stabilization then a 28 week extension

### END.