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18162134
18162134
[ { "id": "18162134__text", "type": "full_text", "text": [ "BackgroundMuch of our current knowledge of the molecular expression profile of human embryonic stem cells (hESCs) is based on transcriptional approaches. These analyses are only partly predictive of protein expression however, and do not sh...
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[]
[]
[]
18286199
18286199
[ { "id": "18286199__text", "type": "full_text", "text": [ "BackgroundHuman embryonic stem cells (hESCs) offer a virtually unlimited source of neural cells for structural repair in neurological disorders, such as stroke. Neural cells can be derived from hESCs either by direct enrichment, or by isola...
[ { "id": "18286199_T1", "type": "Species", "text": [ "human" ], "offsets": [ [ 24042, 24047 ] ], "normalized": [] }, { "id": "18286199_T2", "type": "Anatomy", "text": [ "derma" ], "offsets": [ [ 18639, 1...
[]
[]
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16316465
16316465
[ { "id": "16316465__text", "type": "full_text", "text": [ "BackgroundUsing antibodies to specific protein antigens is the method of choice to assign and identify cell lineage through simultaneous analysis of surface molecules and intracellular markers. Embryonic stem cell research can be benefited ...
[ { "id": "16316465_T1", "type": "Species", "text": [ "human" ], "offsets": [ [ 3043, 3048 ] ], "normalized": [] }, { "id": "16316465_T2", "type": "GeneProtein", "text": [ "Oct3/4" ], "offsets": [ [ 3013, ...
[]
[]
[]
17389645
17389645
[ { "id": "17389645__text", "type": "full_text", "text": [ "Mapping sites within the genome that are hypersensitive to digestion with DNaseI is an important method for identifying DNA elements that regulate transcription. The standard approach to locating these DNaseI-hypersensitive sites (DHSs) has...
[ { "id": "17389645_T1", "type": "Anatomy", "text": [ "brain" ], "offsets": [ [ 8952, 8957 ] ], "normalized": [] }, { "id": "17389645_T2", "type": "GeneProtein", "text": [ "TAL1/SCL" ], "offsets": [ [ 774, ...
[]
[]
[]
17381551
17381551
[ { "id": "17381551__text", "type": "full_text", "text": [ "This work uncovers novel mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans and affect both embryonic and adult stem cells. Specifically, we have examined the effects of aged muscle and sys...
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[]
[]
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16316465_02_introduction
16316465_02_introduction
[ { "id": "16316465_02_introduction__text", "type": "introduction", "text": [ "Although the stem cell concept was introduced decades ago, to date, stem cells can only be defined functionally, not morphologically or phenotypically. Two functions define stem cells. Firstly, they are self-renewing, thu...
[ { "id": "16316465_02_introduction_T1", "type": "CellType", "text": [ "ESCs" ], "offsets": [ [ 2392, 2396 ] ], "normalized": [] }, { "id": "16316465_02_introduction_T2", "type": "CellType", "text": [ "ES" ], "offsets": [ ...
[]
[]
[]
17381551_03_results
17381551_03_results
[ { "id": "17381551_03_results__text", "type": "results", "text": [ "Regenerative responses of adult muscle stem cells and hESCs are dominantly inhibited by the aged systemic milieuPrevious work established that the upregulation of repair-specific molecular signaling mechanisms, such as Notch, and s...
[ { "id": "17381551_03_results_T1", "type": "CellType", "text": [ "satellite cells" ], "offsets": [ [ 2380, 2395 ] ], "normalized": [] }, { "id": "17381551_03_results_T2", "type": "CellType", "text": [ "hESCs" ], "offsets": [ ...
[]
[]
[]
18286199_04_discussion
18286199_04_discussion
[ { "id": "18286199_04_discussion__text", "type": "discussion", "text": [ "Our results indicate that a self-renewable and homogenous population of hNSCs, SD56, was derived from hESCs using defined media supplemented with a specific combination of growth factors. The SD56 hNSCs grew as an adherent mo...
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[]
[]
[]
17381551_01_abstract
17381551_01_abstract
[ { "id": "17381551_01_abstract__text", "type": "abstract", "text": [ "This work uncovers novel mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans and affect both embryonic and adult stem cells. Specifically, we have examined the effects of aged mus...
[ { "id": "17381551_01_abstract_T1", "type": "CellType", "text": [ "hESCs" ], "offsets": [ [ 494, 499 ] ], "normalized": [] }, { "id": "17381551_01_abstract_T2", "type": "GeneProtein", "text": [ "Oct4" ], "offsets": [ [ ...
[]
[]
[]
18162134_06_methods
18162134_06_methods
[ { "id": "18162134_06_methods__text", "type": "methods", "text": [ "Culture of human embryonic stem cellsFor the PowerBlot analysis, enzymatically passaged BG01 hESCs were grown as described previously [23]. These conditions were necessary to scale up the culture to generate the milligram amounts o...
[ { "id": "18162134_06_methods_T1", "type": "GeneProtein", "text": [ "P190" ], "offsets": [ [ 3138, 3142 ] ], "normalized": [] }, { "id": "18162134_06_methods_T2", "type": "CellComponent", "text": [ "karyotypically" ], "offset...
[]
[]
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17389645_05_methods
17389645_05_methods
[ { "id": "17389645_05_methods__text", "type": "methods", "text": [ "Cell cultureCell lines were maintained in culture as previously described (11). Care was taken to ensure maximum viability of cells when taken for experiments. The primary thymocytes used for Figure 2 were prepared by gentle physic...
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[]
[]
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18162134_05_conclusion
18162134_05_conclusion
[ { "id": "18162134_05_conclusion__text", "type": "conclusion", "text": [ "In summary, we generated a focused proteome of hESCs using large-scale western blotting and sorted the detected proteins according to function and signaling pathways. This characterization provides important basic information...
[ { "id": "18162134_05_conclusion_T1", "type": "CellType", "text": [ "hESCs" ], "offsets": [ [ 391, 396 ] ], "normalized": [] }, { "id": "18162134_05_conclusion_T2", "type": "CellType", "text": [ "hESCs" ], "offsets": [ ...
[]
[]
[]
17381551_05_methods
17381551_05_methods
[ { "id": "17381551_05_methods__text", "type": "methods", "text": [ "Animal strainsYoung (2–3 months), C57-BL/6 male mice were obtained from pathogen-free breeding colonies at Jackson Laboratories (Bar Harbor, ME, USA). Aged 22–24 months C57-BL/6 male mice were obtained from the National Institute o...
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[]
[]
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18286199_02_introduction
18286199_02_introduction
[ { "id": "18286199_02_introduction__text", "type": "introduction", "text": [ "To date there have been no effective treatments for improving residual structural and functional deficits resulting from stroke. Current therapeutic approaches, such as the use of thrombolytics, benefit only 1 to 4% of pa...
[ { "id": "18286199_02_introduction_T1", "type": "Anatomy", "text": [ "rosettes" ], "offsets": [ [ 1580, 1588 ] ], "normalized": [] }, { "id": "18286199_02_introduction_T2", "type": "CellType", "text": [ "stem cells" ], "offse...
[]
[]
[]
17389645_01_abstract
17389645_01_abstract
[ { "id": "17389645_01_abstract__text", "type": "abstract", "text": [ "Mapping sites within the genome that are hypersensitive to digestion with DNaseI is an important method for identifying DNA elements that regulate transcription. The standard approach to locating these DNaseI-hypersensitive sites...
[ { "id": "17389645_01_abstract_T1", "type": "GeneProtein", "text": [ "DNaseI" ], "offsets": [ [ 74, 80 ] ], "normalized": [] }, { "id": "17389645_01_abstract_T2", "type": "CellType", "text": [ "K562 cells" ], "offsets": [ ...
[]
[]
[]
17389645_03_results
17389645_03_results
[ { "id": "17389645_03_results__text", "type": "results", "text": [ "Generating a library of DHSsThe basic protocol is outlined in Figure 1. Nuclei are extracted from living cells, then digested on ice for 1 h with a range of DNaseI concentrations, as detailed in the ‘Materials and methods’ sections...
[ { "id": "17389645_03_results_T1", "type": "CellComponent", "text": [ "nuclei" ], "offsets": [ [ 421, 427 ] ], "normalized": [] }, { "id": "17389645_03_results_T2", "type": "Anatomy", "text": [ "myeloid" ], "offsets": [ ...
[]
[]
[]
18162134_02_introduction
18162134_02_introduction
[ { "id": "18162134_02_introduction__text", "type": "introduction", "text": [ "Human embryonic stem cells (hESCs) are pluripotent cells isolated from the inner cell mass of the blastocyst [1]. They can be maintained for prolonged periods in culture and differentiate to representatives of the three g...
[ { "id": "18162134_02_introduction_T1", "type": "CellType", "text": [ "hESCs" ], "offsets": [ [ 5526, 5531 ] ], "normalized": [] }, { "id": "18162134_02_introduction_T2", "type": "CellType", "text": [ "hESCs" ], "offsets": [ ...
[]
[]
[]
18162134_04_discussion
18162134_04_discussion
[ { "id": "18162134_04_discussion__text", "type": "discussion", "text": [ "Attempts to harness the potential of hESCs for models of human embryogenesis and cell therapy applications will be greatly enhanced by a detailed understanding of their molecular characteristics. This includes definition of t...
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[]
[]
[]
16316465_01_abstract
16316465_01_abstract
[ { "id": "16316465_01_abstract__text", "type": "abstract", "text": [ "BackgroundUsing antibodies to specific protein antigens is the method of choice to assign and identify cell lineage through simultaneous analysis of surface molecules and intracellular markers. Embryonic stem cell research can be...
[ { "id": "16316465_01_abstract_T1", "type": "Species", "text": [ "human" ], "offsets": [ [ 491, 496 ] ], "normalized": [] }, { "id": "16316465_01_abstract_T2", "type": "CellType", "text": [ "human embryonic stem cell" ], "off...
[]
[]
[]
18286199_05_methods
18286199_05_methods
[ { "id": "18286199_05_methods__text", "type": "methods", "text": [ "hESC and NSC CulturesThe hESC line H9 (WiCell Research Institute) was propagated every 5 to 7 days on irradiated mouse embryonic fibroblasts. The cell culture media consisted of a 1∶1 mixture of Dulbecco's modified Eagle's medium (...
[ { "id": "18286199_05_methods_T1", "type": "GeneProtein", "text": [ "Anti-Ki67" ], "offsets": [ [ 7693, 7702 ] ], "normalized": [] }, { "id": "18286199_05_methods_T2", "type": "GeneProtein", "text": [ "DCX" ], "offsets": [ ...
[]
[]
[]
16316465_03_results
16316465_03_results
[ { "id": "16316465_03_results__text", "type": "results", "text": [ "Characterization of undifferentiated human ES cells and differentiated EBs by antibodiesAll monoclonal antibodies were initially selected for their abilities to recognize recombinant proteins in direct ELISAs. A subset were also te...
[ { "id": "16316465_03_results_T1", "type": "Anatomy", "text": [ "EBs" ], "offsets": [ [ 71, 74 ] ], "normalized": [] }, { "id": "16316465_03_results_T2", "type": "CellType", "text": [ "EBs" ], "offsets": [ [ 494...
[]
[]
[]
16316465_05_methods
16316465_05_methods
[ { "id": "16316465_05_methods__text", "type": "methods", "text": [ "Cloning and expression of Brachyury, DPPA5, CD9, E-Cadherin, GATA1, GATA6, Nanog, Oct3/4, PDX-1, PODXL, SOX2 and SOX17Brachyury (aa. 1–202), DPPA5 (a.a. 1–116), GATA1 (a.a. 1–413), GATA6 (aa. 1–449), Nanog (aa. 153–305), Oct3/4 (aa...
[ { "id": "16316465_05_methods_T1", "type": "CellType", "text": [ "mouse NSO cells" ], "offsets": [ [ 399, 414 ] ], "normalized": [] }, { "id": "16316465_05_methods_T2", "type": "GeneProtein", "text": [ "IgG" ], "offsets": [ ...
[]
[]
[]
16316465_04_conclusion
16316465_04_conclusion
[ { "id": "16316465_04_conclusion__text", "type": "conclusion", "text": [ "The expression patterns detected using antibodies developed in our facility are consistent with data reported using reverse transcriptase-polymerase chain reaction or cDNA microarrays. Moreover several of the monoclonal antib...
[]
[]
[]
[]
18286199_03_results
18286199_03_results
[ { "id": "18286199_03_results__text", "type": "results", "text": [ "1. In vitro isolation, growth and differentiation of hESC-derived hNSCsThe hESCs were maintained and expanded on mouse feeder layer in media supplemented with bFGF (Figure 1A). After cell dissociation, a portion of the hESCs was cu...
[ { "id": "18286199_03_results_T1", "type": "GeneProtein", "text": [ "EGF" ], "offsets": [ [ 270, 273 ] ], "normalized": [] }, { "id": "18286199_03_results_T2", "type": "GeneProtein", "text": [ "MBP" ], "offsets": [ [ ...
[]
[]
[]
18286199_01_abstract
18286199_01_abstract
[ { "id": "18286199_01_abstract__text", "type": "abstract", "text": [ "BackgroundHuman embryonic stem cells (hESCs) offer a virtually unlimited source of neural cells for structural repair in neurological disorders, such as stroke. Neural cells can be derived from hESCs either by direct enrichment, ...
[ { "id": "18286199_01_abstract_T1", "type": "CellLine", "text": [ "SD56" ], "offsets": [ [ 1452, 1456 ] ], "normalized": [] }, { "id": "18286199_01_abstract_T2", "type": "CellLine", "text": [ "SD56" ], "offsets": [ [ ...
[]
[]
[]
17381551_04_discussion
17381551_04_discussion
[ { "id": "17381551_04_discussion__text", "type": "discussion", "text": [ "The data presented here establish for the first time that both the local environment of old differentiated organ, e.g., skeletal muscle and the systemic milieu dramatically affect the regenerative potential of both hESCs and ...
[ { "id": "17381551_04_discussion_T1", "type": "CellType", "text": [ "hESCs" ], "offsets": [ [ 3668, 3673 ] ], "normalized": [] }, { "id": "17381551_04_discussion_T2", "type": "Species", "text": [ "mouse" ], "offsets": [ ...
[]
[]
[]
18162134_01_abstract
18162134_01_abstract
[ { "id": "18162134_01_abstract__text", "type": "abstract", "text": [ "BackgroundMuch of our current knowledge of the molecular expression profile of human embryonic stem cells (hESCs) is based on transcriptional approaches. These analyses are only partly predictive of protein expression however, an...
[ { "id": "18162134_01_abstract_T1", "type": "CellType", "text": [ "pluripotent stem cells" ], "offsets": [ [ 338, 360 ] ], "normalized": [] }, { "id": "18162134_01_abstract_T2", "type": "CellType", "text": [ "human embryonic stem cel...
[]
[]
[]
17389645_02_introduction
17389645_02_introduction
[ { "id": "17389645_02_introduction__text", "type": "introduction", "text": [ "Mapping the location of DNaseI-hypersensitive sites (DHSs) remains central to developing our understanding of transcriptional regulation. Elements with a range of transcriptional regulatory functions have been identified ...
[ { "id": "17389645_02_introduction_T1", "type": "CellType", "text": [ "embryonic stem (hES) cell" ], "offsets": [ [ 2189, 2214 ] ], "normalized": [] }, { "id": "17389645_02_introduction_T2", "type": "CellComponent", "text": [ "DNA" ...
[]
[]
[]
18162134_03_results
18162134_03_results
[ { "id": "18162134_03_results__text", "type": "results", "text": [ "PowerBlot analysis of hESCsWe first employed a large-scale western blot screen, the PowerBlot system, to profile protein expression in undifferentiated hESCs. This system used 934 antibodies toward proteins representing 22 diverse ...
[ { "id": "18162134_03_results_T1", "type": "GeneProtein", "text": [ "SEC8L1" ], "offsets": [ [ 16442, 16448 ] ], "normalized": [] }, { "id": "18162134_03_results_T2", "type": "GeneProtein", "text": [ "protein kinases" ], "off...
[]
[]
[]
17389645_04_discussion
17389645_04_discussion
[ { "id": "17389645_04_discussion__text", "type": "discussion", "text": [ "The development of techniques that permit the rapid comparative mapping of DHS between different cell types will greatly facilitate the study of transcriptional regulation in both normal and diseased cells. Recently published...
[ { "id": "17389645_04_discussion_T1", "type": "CellComponent", "text": [ "DNA" ], "offsets": [ [ 1092, 1095 ] ], "normalized": [] }, { "id": "17389645_04_discussion_T2", "type": "CellComponent", "text": [ "DNA" ], "offsets": ...
[]
[]
[]
17381551_02_introduction
17381551_02_introduction
[ { "id": "17381551_02_introduction__text", "type": "introduction", "text": [ "Embryonic stem cells (ESCs) are distinguished by their ability to self-renew and to differentiate into any other cell type via asymmetric cell divisions, in which one daughter cell maintains ‘stemness’ while the other dau...
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1.0alpha7.train.0
24813911
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1.0alpha7.train.1
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1.0alpha7.train.2
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[ { "id": "1.0alpha7.train.2.rel0s1.0alpha7.train.2.ent0_0.o1.0alpha7.train.2.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.2.ent0_0", "arg2_id": "1.0alpha7.train.2.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.2.rel1s1.0alpha7.train.2.ent1_0.o1.0alpha7.train.2.ent3_0", ...
1.0alpha7.train.3
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1.0alpha7.train.4
2062980
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1.0alpha7.train.5
609763
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1.0alpha7.train.6
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1.0alpha7.train.7
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1.0alpha7.train.8
15405236
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1.0alpha7.train.9
19792388
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1.0alpha7.train.10
2679916
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1.0alpha7.train.11
25223498
[ { "id": "1.0alpha7.train.11.sent", "type": "sentence", "text": [ "Mena binds directly to Profilin, an actin-binding protein that modulates actin polymerization." ], "offsets": [ [ 0, 94 ] ] } ]
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1.0alpha7.train.12
5083349
[ { "id": "1.0alpha7.train.12.sent", "type": "sentence", "text": [ "Mirk Binds to a Specific Region within the CBP-binding Region of HNF1α" ], "offsets": [ [ 0, 70 ] ] } ]
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1.0alpha7.train.14
11694484
[ { "id": "1.0alpha7.train.14.sent", "type": "sentence", "text": [ "Both GD and Snk bind to heparin - Sepharose, providing a link between the pipe-defined ventral prepattern and the protease cascade." ], "offsets": [ [ 0, 131 ] ] } ]
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1.0alpha7.train.15
18075455
[ { "id": "1.0alpha7.train.15.sent", "type": "sentence", "text": [ " All of these residues, except Ser45, are located close to site of cofilin implicated genetically in actin binding, suggesting they also form part of the actin-binding surface. " ], "offsets": [ [ 0, ...
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1.0alpha7.train.16
19760877
[ { "id": "1.0alpha7.train.16.sent", "type": "sentence", "text": [ "We have shown that CES-1 can bind to Snail-binding sites/E-boxes in the egl-1 locus in vitro, which are required for the ability of the ces-2 lf mutation n732 to block the death of the NSM sister cells in vivo." ], "offsets"...
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1.0alpha7.train.17
19725957
[ { "id": "1.0alpha7.train.17.sent", "type": "sentence", "text": [ "This led us to investigate if (and to demonstrate that) Foxa2 binds Lim1 and Gsc." ], "offsets": [ [ 0, 81 ] ] } ]
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1.0alpha7.train.18
2972695
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1.0alpha7.train.19
15275411
[ { "id": "1.0alpha7.train.19.sent", "type": "sentence", "text": [ "Can we speculate as to where Phyl might bind Sina?" ], "offsets": [ [ 0, 50 ] ] } ]
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1.0alpha7.train.20
23310850
[ { "id": "1.0alpha7.train.20.sent", "type": "sentence", "text": [ "The majority of dCLK is bound to CYC during a daily cycle." ], "offsets": [ [ 0, 60 ] ] } ]
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1.0alpha7.train.21
15755010
[ { "id": "1.0alpha7.train.21.sent", "type": "sentence", "text": [ "In these clones, binding of p16 to cdk4 and cdk6 abrogated binding of cyclin D1, p27 KIP1, and p21 WAF1/CIP1." ], "offsets": [ [ 0, 109 ] ] } ]
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1.0alpha7.train.22
9725155
[ { "id": "1.0alpha7.train.22.sent", "type": "sentence", "text": [ "Whereas FK506 stimulates the binding of FKBP12 to calcineurin ( 42), stoichiometric quantities of FK506 dissociate FKBP12 from the ryanodine and IP3 receptors ( 11, 36)." ], "offsets": [ [ 0, 169 ...
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1.0alpha7.train.23
23571761
[ { "id": "1.0alpha7.train.23.sent", "type": "sentence", "text": [ "For each binding reaction, 5 mug of GST-GTPase bound to 25 mul of glutathione-Sepharose beads was mixed with an aliquot of cell extract containing 1 mg of protein for 1 hr at 4 degrees C." ], "offsets": [ [ 0, ...
[ { "id": "1.0alpha7.train.23.ent0_0", "type": "experimental-construct", "text": [ "GST-GTPase" ], "offsets": [ [ 36, 46 ] ], "normalized": [] }, { "id": "1.0alpha7.train.23.ent1_0", "type": "protein-family", "text": [ "GTPase" ],...
[]
[ { "id": "1.0alpha7.train.23.coref0", "entity_ids": [ "1.0alpha7.train.23.ent0_0" ] }, { "id": "1.0alpha7.train.23.coref1", "entity_ids": [ "1.0alpha7.train.23.ent1_0" ] }, { "id": "1.0alpha7.train.23.coref2", "entity_ids": [ "1.0alpha7.train.23.ent2_0" ]...
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1.0alpha7.train.24
15500177
[ { "id": "1.0alpha7.train.24.sent", "type": "sentence", "text": [ "The EGF-like domain of Aos binds directly to DER at the sSpi-binding site and interferes with the binding of sSpi to DER (Fig. 8B)." ], "offsets": [ [ 0, 131 ] ] } ]
[ { "id": "1.0alpha7.train.24.ent0_0", "type": "protein", "text": [ "DER" ], "offsets": [ [ 45, 48 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "P04412" } ] }, { "id": "1.0alpha7.train.24.ent1_1", "type"...
[]
[ { "id": "1.0alpha7.train.24.coref0", "entity_ids": [ "1.0alpha7.train.24.ent0_0", "1.0alpha7.train.24.ent1_1" ] }, { "id": "1.0alpha7.train.24.coref1", "entity_ids": [ "1.0alpha7.train.24.ent2_0" ] }, { "id": "1.0alpha7.train.24.coref2", "entity_ids": [ ...
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1.0alpha7.train.25
4281921
[ { "id": "1.0alpha7.train.25.sent", "type": "sentence", "text": [ "This site has been shown to be differentially protected by TGF-β treatment in experiments of DNA footprinting (data not shown), and in vivo positioning of Sp1 using the PINPOINT technique maps the Sp1 binding site over the predicted...
[ { "id": "1.0alpha7.train.25.ent0_0", "type": "protein", "text": [ "Sp1" ], "offsets": [ [ 155, 158 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "6667" }, { "db_name": "hgnc", "db_id": "SP1" ...
[]
[ { "id": "1.0alpha7.train.25.coref0", "entity_ids": [ "1.0alpha7.train.25.ent0_0", "1.0alpha7.train.25.ent1_1" ] }, { "id": "1.0alpha7.train.25.coref1", "entity_ids": [ "1.0alpha7.train.25.ent2_0" ] }, { "id": "1.0alpha7.train.25.coref2", "entity_ids": [ ...
[ { "id": "1.0alpha7.train.25.rel0s1.0alpha7.train.25.ent0_0.o1.0alpha7.train.25.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.25.ent0_0", "arg2_id": "1.0alpha7.train.25.ent3_0", "normalized": [] }, { "id": "1.0alpha7.train.25.rel0s1.0alpha7.train.25.ent1_1.o1.0alpha7.train.25.ent3_...
1.0alpha7.train.26
9635775
[ { "id": "1.0alpha7.train.26.sent", "type": "sentence", "text": [ "To explore the functional significance of mitosis-specific phosphorylation of MYPT, the myosin binding activities of MYPT from mitotic or interphase cells were compared." ], "offsets": [ [ 0, 169 ...
[ { "id": "1.0alpha7.train.26.ent0_0", "type": "protein-family", "text": [ "MYPT" ], "offsets": [ [ 78, 82 ] ], "normalized": [] }, { "id": "1.0alpha7.train.26.ent1_1", "type": "protein-family", "text": [ "MYPT" ], "offsets": ...
[]
[ { "id": "1.0alpha7.train.26.coref0", "entity_ids": [ "1.0alpha7.train.26.ent0_0", "1.0alpha7.train.26.ent1_1" ] }, { "id": "1.0alpha7.train.26.coref1", "entity_ids": [ "1.0alpha7.train.26.ent2_0" ] } ]
[ { "id": "1.0alpha7.train.26.rel0s1.0alpha7.train.26.ent0_0.o1.0alpha7.train.26.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.26.ent0_0", "arg2_id": "1.0alpha7.train.26.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.26.rel0s1.0alpha7.train.26.ent1_1.o1.0alpha7.train.26.ent2_...
1.0alpha7.train.27
15954894
[ { "id": "1.0alpha7.train.27.sent", "type": "sentence", "text": [ "(C) Adf-1 binds the same regions of TAFII110 and TAFII250 in vivo as it does in vitro." ], "offsets": [ [ 0, 86 ] ] } ]
[ { "id": "1.0alpha7.train.27.ent0_0", "type": "protein", "text": [ "Adf-1" ], "offsets": [ [ 4, 9 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "A0A0B4KEJ0" } ] }, { "id": "1.0alpha7.train.27.ent1_0", "t...
[]
[ { "id": "1.0alpha7.train.27.coref0", "entity_ids": [ "1.0alpha7.train.27.ent0_0" ] }, { "id": "1.0alpha7.train.27.coref1", "entity_ids": [ "1.0alpha7.train.27.ent1_0" ] }, { "id": "1.0alpha7.train.27.coref2", "entity_ids": [ "1.0alpha7.train.27.ent2_0" ]...
[ { "id": "1.0alpha7.train.27.rel0s1.0alpha7.train.27.ent0_0.o1.0alpha7.train.27.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.27.ent0_0", "arg2_id": "1.0alpha7.train.27.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.27.rel1s1.0alpha7.train.27.ent0_0.o1.0alpha7.train.27.ent1_...
1.0alpha7.train.28
19845696
[ { "id": "1.0alpha7.train.28.sent", "type": "sentence", "text": [ "The intricate region was previously shown to contain functional Ets-1 in addition to CREB, LEF and ds binding sites." ], "offsets": [ [ 0, 116 ] ] } ]
[ { "id": "1.0alpha7.train.28.ent0_0", "type": "protein", "text": [ "CREB" ], "offsets": [ [ 85, 89 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "1385" }, { "db_name": "hgnc", "db_id": "CREB1" ...
[]
[ { "id": "1.0alpha7.train.28.coref0", "entity_ids": [ "1.0alpha7.train.28.ent0_0" ] }, { "id": "1.0alpha7.train.28.coref1", "entity_ids": [ "1.0alpha7.train.28.ent1_0" ] }, { "id": "1.0alpha7.train.28.coref2", "entity_ids": [ "1.0alpha7.train.28.ent2_0" ]...
[]
1.0alpha7.train.29
15179628
[ { "id": "1.0alpha7.train.29.sent", "type": "sentence", "text": [ "Inducer-specific binding of Ets-1 to the endogenous TNF-alpha promoter." ], "offsets": [ [ 0, 71 ] ] } ]
[ { "id": "1.0alpha7.train.29.ent0_0", "type": "DNA", "text": [ "TNF-alpha promoter" ], "offsets": [ [ 52, 70 ] ], "normalized": [] }, { "id": "1.0alpha7.train.29.ent1_0", "type": "protein", "text": [ "Ets-1" ], "offsets": [ ...
[]
[ { "id": "1.0alpha7.train.29.coref0", "entity_ids": [ "1.0alpha7.train.29.ent0_0" ] }, { "id": "1.0alpha7.train.29.coref1", "entity_ids": [ "1.0alpha7.train.29.ent1_0" ] } ]
[ { "id": "1.0alpha7.train.29.rel0s1.0alpha7.train.29.ent0_0.o1.0alpha7.train.29.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.29.ent0_0", "arg2_id": "1.0alpha7.train.29.ent1_0", "normalized": [] } ]
1.0alpha7.train.30
16352875
[ { "id": "1.0alpha7.train.30.sent", "type": "sentence", "text": [ "To test whether the cytoplasmic domains of other neuroligins also interact with PSD-95, and whether isoforms of PSD-95 also bind to neuroligins, we quantified the yeast two-hybrid interactions by measuring beta-galactosidase transac...
[ { "id": "1.0alpha7.train.30.ent0_0", "type": "protein-family", "text": [ "neuroligins" ], "offsets": [ [ 49, 60 ] ], "normalized": [ { "db_name": "interpro", "db_id": "IPR000460" } ] }, { "id": "1.0alpha7.train.30....
[]
[ { "id": "1.0alpha7.train.30.coref0", "entity_ids": [ "1.0alpha7.train.30.ent0_0", "1.0alpha7.train.30.ent1_1" ] }, { "id": "1.0alpha7.train.30.coref1", "entity_ids": [ "1.0alpha7.train.30.ent2_0" ] }, { "id": "1.0alpha7.train.30.coref2", "entity_ids": [ ...
[ { "id": "1.0alpha7.train.30.rel0s1.0alpha7.train.30.ent0_0.o1.0alpha7.train.30.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.30.ent0_0", "arg2_id": "1.0alpha7.train.30.ent3_0", "normalized": [] }, { "id": "1.0alpha7.train.30.rel0s1.0alpha7.train.30.ent0_0.o1.0alpha7.train.30.ent4_...
1.0alpha7.train.31
3737303
[ { "id": "1.0alpha7.train.31.sent", "type": "sentence", "text": [ "DNA Binding of Smad5 and Smad4 to the GC-rich Sequence" ], "offsets": [ [ 0, 54 ] ] } ]
[ { "id": "1.0alpha7.train.31.ent0_0", "type": "DNA", "text": [ "GC-rich Sequence" ], "offsets": [ [ 38, 54 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "25782" }, { "db_name": "hgnc", "db_id": "...
[]
[ { "id": "1.0alpha7.train.31.coref0", "entity_ids": [ "1.0alpha7.train.31.ent0_0", "1.0alpha7.train.31.ent1_0" ] }, { "id": "1.0alpha7.train.31.coref1", "entity_ids": [ "1.0alpha7.train.31.ent2_0" ] }, { "id": "1.0alpha7.train.31.coref2", "entity_ids": [ ...
[ { "id": "1.0alpha7.train.31.rel0s1.0alpha7.train.31.ent0_0.o1.0alpha7.train.31.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.31.ent0_0", "arg2_id": "1.0alpha7.train.31.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.31.rel0s1.0alpha7.train.31.ent1_0.o1.0alpha7.train.31.ent2_...
1.0alpha7.train.33
11560304
[ { "id": "1.0alpha7.train.33.sent", "type": "sentence", "text": [ "Grundhoff,A.T., Kremmer,E., Tureci,O., Glieden,A., Gindorf,C., Atz,J., Muller-Lantzsch,N., Schubach,W.H. and Grasser,F.A. (1999) Characterisation of DP103, a novel DEAD box protein that binds to the Epstein - Barr virus nuclear prot...
[ { "id": "1.0alpha7.train.33.ent0_0", "type": "protein", "text": [ "EBNA2" ], "offsets": [ [ 237, 242 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "P12978" } ] }, { "id": "1.0alpha7.train.33.ent1_0", "t...
[]
[ { "id": "1.0alpha7.train.33.coref0", "entity_ids": [ "1.0alpha7.train.33.ent0_0" ] }, { "id": "1.0alpha7.train.33.coref1", "entity_ids": [ "1.0alpha7.train.33.ent1_0" ] }, { "id": "1.0alpha7.train.33.coref2", "entity_ids": [ "1.0alpha7.train.33.ent2_0" ]...
[ { "id": "1.0alpha7.train.33.rel0s1.0alpha7.train.33.ent0_0.o1.0alpha7.train.33.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.33.ent0_0", "arg2_id": "1.0alpha7.train.33.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.33.rel1s1.0alpha7.train.33.ent1_0.o1.0alpha7.train.33.ent2_...
1.0alpha7.train.34
15685147
[ { "id": "1.0alpha7.train.34.sent", "type": "sentence", "text": [ "TPA directly binds PKC, causing an increase in PKC's affinity for calcium and the stimulation of enzymatic activity." ], "offsets": [ [ 0, 116 ] ] } ]
[ { "id": "1.0alpha7.train.34.ent0_0", "type": "protein-family", "text": [ "PKC" ], "offsets": [ [ 19, 22 ] ], "normalized": [ { "db_name": "interpro", "db_id": "IPR014376" } ] }, { "id": "1.0alpha7.train.34.ent1_1",...
[]
[ { "id": "1.0alpha7.train.34.coref0", "entity_ids": [ "1.0alpha7.train.34.ent0_0", "1.0alpha7.train.34.ent1_1" ] }, { "id": "1.0alpha7.train.34.coref1", "entity_ids": [ "1.0alpha7.train.34.ent2_0" ] }, { "id": "1.0alpha7.train.34.coref2", "entity_ids": [ ...
[ { "id": "1.0alpha7.train.34.rel0s1.0alpha7.train.34.ent0_0.o1.0alpha7.train.34.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.34.ent0_0", "arg2_id": "1.0alpha7.train.34.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.34.rel0s1.0alpha7.train.34.ent1_1.o1.0alpha7.train.34.ent2_...
1.0alpha7.train.35
24566933
[ { "id": "1.0alpha7.train.35.sent", "type": "sentence", "text": [ "The MKP-3 EB domain binding to ERK2 was not dependent upon ERK2 phosphorylation in our NMR titration experiments, consistent with the previous study of MKP-3 and ERK2 binding with a GST pulldown assay (Camps et al., 1998 )." ], ...
[ { "id": "1.0alpha7.train.35.ent0_0", "type": "protein", "text": [ "ERK2" ], "offsets": [ [ 31, 35 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "5594" }, { "db_name": "hgnc", "db_id": "MAPK1" ...
[]
[ { "id": "1.0alpha7.train.35.coref0", "entity_ids": [ "1.0alpha7.train.35.ent0_0", "1.0alpha7.train.35.ent1_1", "1.0alpha7.train.35.ent2_2" ] }, { "id": "1.0alpha7.train.35.coref1", "entity_ids": [ "1.0alpha7.train.35.ent3_0" ] }, { "id": "1.0alpha7.train.3...
[ { "id": "1.0alpha7.train.35.rel0s1.0alpha7.train.35.ent0_0.o1.0alpha7.train.35.ent4_0", "type": "bind", "arg1_id": "1.0alpha7.train.35.ent0_0", "arg2_id": "1.0alpha7.train.35.ent4_0", "normalized": [] }, { "id": "1.0alpha7.train.35.rel0s1.0alpha7.train.35.ent0_0.o1.0alpha7.train.35.ent5_...
1.0alpha7.train.36
15862392
[ { "id": "1.0alpha7.train.36.sent", "type": "sentence", "text": [ "Interestingly, the Rb protein binds to TAFII250 at an amino-terminal site which overlaps the NTK domain ( 38)." ], "offsets": [ [ 0, 110 ] ] } ]
[ { "id": "1.0alpha7.train.36.ent0_0", "type": "protein", "text": [ "TAFII250" ], "offsets": [ [ 39, 47 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "P51123" } ] }, { "id": "1.0alpha7.train.36.ent1_0", "...
[]
[ { "id": "1.0alpha7.train.36.coref0", "entity_ids": [ "1.0alpha7.train.36.ent0_0" ] }, { "id": "1.0alpha7.train.36.coref1", "entity_ids": [ "1.0alpha7.train.36.ent1_0" ] }, { "id": "1.0alpha7.train.36.coref2", "entity_ids": [ "1.0alpha7.train.36.ent2_0" ]...
[ { "id": "1.0alpha7.train.36.rel0s1.0alpha7.train.36.ent0_0.o1.0alpha7.train.36.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.36.ent0_0", "arg2_id": "1.0alpha7.train.36.ent2_0", "normalized": [] } ]
1.0alpha7.train.37
3573748
[ { "id": "1.0alpha7.train.37.sent", "type": "sentence", "text": [ "The alpha-helical C terminus of AIP, which is outside the tetratricopeptide repeat domain, is absolutely required for binding to AhR as shown by deletions of the C-terminal 5 amino acids or alanine-scanning mutagenesis, but it is no...
[ { "id": "1.0alpha7.train.37.ent0_0", "type": "protein", "text": [ "AhR" ], "offsets": [ [ 129, 132 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "196" }, { "db_name": "hgnc", "db_id": "AHR" ...
[]
[ { "id": "1.0alpha7.train.37.coref0", "entity_ids": [ "1.0alpha7.train.37.ent0_0" ] }, { "id": "1.0alpha7.train.37.coref1", "entity_ids": [ "1.0alpha7.train.37.ent1_0" ] }, { "id": "1.0alpha7.train.37.coref2", "entity_ids": [ "1.0alpha7.train.37.ent2_0" ]...
[ { "id": "1.0alpha7.train.37.rel0s1.0alpha7.train.37.ent0_0.o1.0alpha7.train.37.ent3_0", "type": "bind", "arg1_id": "1.0alpha7.train.37.ent0_0", "arg2_id": "1.0alpha7.train.37.ent3_0", "normalized": [] }, { "id": "1.0alpha7.train.37.rel0s1.0alpha7.train.37.ent0_0.o1.0alpha7.train.37.ent4_...
1.0alpha7.train.38
1380101
[ { "id": "1.0alpha7.train.38.sent", "type": "sentence", "text": [ "Thus, the results of both types of binding assays argue that stable binding of ELL to RNA polymerase II is not sufficient for inhibition of promoter-specific initiation." ], "offsets": [ [ 0, 169 ...
[ { "id": "1.0alpha7.train.38.ent0_0", "type": "protein-complex", "text": [ "RNA polymerase II" ], "offsets": [ [ 86, 103 ] ], "normalized": [] }, { "id": "1.0alpha7.train.38.ent1_0", "type": "protein-family", "text": [ "ELL" ], ...
[]
[ { "id": "1.0alpha7.train.38.coref0", "entity_ids": [ "1.0alpha7.train.38.ent0_0" ] }, { "id": "1.0alpha7.train.38.coref1", "entity_ids": [ "1.0alpha7.train.38.ent1_0" ] } ]
[ { "id": "1.0alpha7.train.38.rel0s1.0alpha7.train.38.ent0_0.o1.0alpha7.train.38.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.38.ent0_0", "arg2_id": "1.0alpha7.train.38.ent1_0", "normalized": [] } ]
1.0alpha7.train.39
2712406
[ { "id": "1.0alpha7.train.39.sent", "type": "sentence", "text": [ " Growth arrest by TGF-beta is dependent on Rb and interfered with by direct binding of E1A to Rb ( 33, 34, 37). " ], "offsets": [ [ 0, 119 ] ] } ]
[ { "id": "1.0alpha7.train.39.ent0_0", "type": "protein", "text": [ "E1A" ], "offsets": [ [ 90, 93 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "P03255" } ] }, { "id": "1.0alpha7.train.39.ent1_0", "type"...
[]
[ { "id": "1.0alpha7.train.39.coref0", "entity_ids": [ "1.0alpha7.train.39.ent0_0" ] }, { "id": "1.0alpha7.train.39.coref1", "entity_ids": [ "1.0alpha7.train.39.ent1_0", "1.0alpha7.train.39.ent2_1" ] }, { "id": "1.0alpha7.train.39.coref2", "entity_ids": [ ...
[ { "id": "1.0alpha7.train.39.rel0s1.0alpha7.train.39.ent0_0.o1.0alpha7.train.39.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.39.ent0_0", "arg2_id": "1.0alpha7.train.39.ent1_0", "normalized": [] }, { "id": "1.0alpha7.train.39.rel0s1.0alpha7.train.39.ent0_0.o1.0alpha7.train.39.ent2_...
1.0alpha7.train.40
2528920
[ { "id": "1.0alpha7.train.40.sent", "type": "sentence", "text": [ "In an effort to identify the PG that binds to IFN-gamma, we performed Western blot analysis. " ], "offsets": [ [ 0, 96 ] ] } ]
[ { "id": "1.0alpha7.train.40.ent0_0", "type": "protein", "text": [ "IFN-gamma" ], "offsets": [ [ 48, 57 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "3458" }, { "db_name": "hgnc", "db_id": "IFNG...
[]
[ { "id": "1.0alpha7.train.40.coref0", "entity_ids": [ "1.0alpha7.train.40.ent0_0" ] }, { "id": "1.0alpha7.train.40.coref1", "entity_ids": [ "1.0alpha7.train.40.ent1_0" ] } ]
[ { "id": "1.0alpha7.train.40.rel0s1.0alpha7.train.40.ent0_0.o1.0alpha7.train.40.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.40.ent0_0", "arg2_id": "1.0alpha7.train.40.ent1_0", "normalized": [] } ]
1.0alpha7.train.41
15213790
[ { "id": "1.0alpha7.train.41.sent", "type": "sentence", "text": [ "Both E1A and PU.1 bind to the CH3 domain of CBP but require additional contacts for full CBP inhibition." ], "offsets": [ [ 0, 109 ] ] } ]
[ { "id": "1.0alpha7.train.41.ent0_0", "type": "protein", "text": [ "E1A" ], "offsets": [ [ 6, 9 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "P03255" } ] }, { "id": "1.0alpha7.train.41.ent1_0", "type": ...
[]
[ { "id": "1.0alpha7.train.41.coref0", "entity_ids": [ "1.0alpha7.train.41.ent0_0" ] }, { "id": "1.0alpha7.train.41.coref1", "entity_ids": [ "1.0alpha7.train.41.ent1_0", "1.0alpha7.train.41.ent2_1" ] }, { "id": "1.0alpha7.train.41.coref2", "entity_ids": [ ...
[ { "id": "1.0alpha7.train.41.rel0s1.0alpha7.train.41.ent0_0.o1.0alpha7.train.41.ent1_0", "type": "bind", "arg1_id": "1.0alpha7.train.41.ent0_0", "arg2_id": "1.0alpha7.train.41.ent1_0", "normalized": [] }, { "id": "1.0alpha7.train.41.rel0s1.0alpha7.train.41.ent0_0.o1.0alpha7.train.41.ent2_...
1.0alpha7.train.42
15178756
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1.0alpha7.train.43
1989374
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1.0alpha7.train.44
22546615
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1.0alpha7.train.45
6981221
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1.0alpha7.train.46
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1.0alpha7.train.47
5336461
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1.0alpha7.train.48
18184622
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1.0alpha7.train.49
16888707
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1.0alpha7.train.50
19537787
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1.0alpha7.train.51
20533795
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1.0alpha7.train.52
5881211
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1.0alpha7.train.53
1070296
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1.0alpha7.train.54
665872
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1.0alpha7.train.55
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1.0alpha7.train.56
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1.0alpha7.train.57
11310367
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1.0alpha7.train.58
7097765
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1.0alpha7.train.59
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1.0alpha7.train.60
15386609
[ { "id": "1.0alpha7.train.60.sent", "type": "sentence", "text": [ "E2Fs bind directly to Rb, p107, and p130, and we have previously shown that these proteins are components of the transcription complexes formed on E2F target promoters in vivo ( 49)." ], "offsets": [ [ 0, ...
[ { "id": "1.0alpha7.train.60.ent0_0", "type": "DNA", "text": [ "E2F target promoters" ], "offsets": [ [ 147, 167 ] ], "normalized": [] }, { "id": "1.0alpha7.train.60.ent1_0", "type": "protein-family", "text": [ "E2F" ], "offs...
[]
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1.0alpha7.train.61
9369450
[ { "id": "1.0alpha7.train.61.sent", "type": "sentence", "text": [ "AAK1 localizes to regions active in endocytosis AAK1 binds directly to AP2." ], "offsets": [ [ 0, 75 ] ] } ]
[ { "id": "1.0alpha7.train.61.ent0_0", "type": "protein", "text": [ "AP2" ], "offsets": [ [ 71, 74 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "7020" }, { "db_name": "hgnc", "db_id": "TFAP2A" ...
[]
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1.0alpha7.train.62
2498077
[ { "id": "1.0alpha7.train.62.sent", "type": "sentence", "text": [ "Both these regions of p300/CBP bind to the transactivation domain of Ets-2, whereas the C-terminal region binds only to the DNA binding domain of Ets-2." ], "offsets": [ [ 0, 152 ] ] } ]
[ { "id": "1.0alpha7.train.62.ent0_0", "type": "protein-family", "text": [ "p300/CBP" ], "offsets": [ [ 22, 30 ] ], "normalized": [ { "db_name": "interpro", "db_id": "IPR038547" } ] }, { "id": "1.0alpha7.train.62.ent...
[]
[ { "id": "1.0alpha7.train.62.coref0", "entity_ids": [ "1.0alpha7.train.62.ent0_0" ] }, { "id": "1.0alpha7.train.62.coref1", "entity_ids": [ "1.0alpha7.train.62.ent1_0" ] }, { "id": "1.0alpha7.train.62.coref2", "entity_ids": [ "1.0alpha7.train.62.ent2_0", ...
[ { "id": "1.0alpha7.train.62.rel0s1.0alpha7.train.62.ent0_0.o1.0alpha7.train.62.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.62.ent0_0", "arg2_id": "1.0alpha7.train.62.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.62.rel0s1.0alpha7.train.62.ent0_0.o1.0alpha7.train.62.ent3_...
1.0alpha7.train.63
17880851
[ { "id": "1.0alpha7.train.63.sent", "type": "sentence", "text": [ "The major head protein of bacteriophage T4 binds specifically to elongation factor Tu." ], "offsets": [ [ 0, 86 ] ] } ]
[ { "id": "1.0alpha7.train.63.ent0_0", "type": "protein-family", "text": [ "elongation factor Tu" ], "offsets": [ [ 65, 85 ] ], "normalized": [ { "db_name": "interpro", "db_id": "IPR004541" } ] }, { "id": "1.0alpha7....
[]
[ { "id": "1.0alpha7.train.63.coref0", "entity_ids": [ "1.0alpha7.train.63.ent0_0" ] }, { "id": "1.0alpha7.train.63.coref1", "entity_ids": [ "1.0alpha7.train.63.ent1_0" ] }, { "id": "1.0alpha7.train.63.coref2", "entity_ids": [ "1.0alpha7.train.63.ent2_0" ]...
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1.0alpha7.train.64
13063305
[ { "id": "1.0alpha7.train.64.sent", "type": "sentence", "text": [ "This Psc binding might potentiate the action of a weak Pc- and Ph-binding PRE present in the bxd-Ubx-lacZ vector." ], "offsets": [ [ 0, 118 ] ] } ]
[ { "id": "1.0alpha7.train.64.ent0_0", "type": "protein", "text": [ "Psc" ], "offsets": [ [ 6, 9 ] ], "normalized": [ { "db_name": "uniprot", "db_id": "D0Z760" } ] }, { "id": "1.0alpha7.train.64.ent1_0", "type": ...
[]
[ { "id": "1.0alpha7.train.64.coref0", "entity_ids": [ "1.0alpha7.train.64.ent0_0" ] }, { "id": "1.0alpha7.train.64.coref1", "entity_ids": [ "1.0alpha7.train.64.ent1_0" ] }, { "id": "1.0alpha7.train.64.coref2", "entity_ids": [ "1.0alpha7.train.64.ent2_0" ]...
[]
1.0alpha7.train.65
20508399
[ { "id": "1.0alpha7.train.65.sent", "type": "sentence", "text": [ "The ability to form H-DNA cannot substitute for GAGA factor binding to the ( CT)n sequence." ], "offsets": [ [ 0, 91 ] ] } ]
[ { "id": "1.0alpha7.train.65.ent0_0", "type": "DNA", "text": [ "H-DNA" ], "offsets": [ [ 20, 25 ] ], "normalized": [] }, { "id": "1.0alpha7.train.65.ent1_0", "type": "protein", "text": [ "GAGA factor" ], "offsets": [ [ ...
[]
[ { "id": "1.0alpha7.train.65.coref0", "entity_ids": [ "1.0alpha7.train.65.ent0_0" ] }, { "id": "1.0alpha7.train.65.coref1", "entity_ids": [ "1.0alpha7.train.65.ent1_0" ] }, { "id": "1.0alpha7.train.65.coref2", "entity_ids": [ "1.0alpha7.train.65.ent2_0" ]...
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1.0alpha7.train.66
11328273
[ { "id": "1.0alpha7.train.66.sent", "type": "sentence", "text": [ "We predict that these PH domains will also bind PI3K products with high affinity, but this has not yet been tested or was inconclusive." ], "offsets": [ [ 0, 135 ] ] } ]
[ { "id": "1.0alpha7.train.66.ent0_0", "type": "protein-domain", "text": [ "PH" ], "offsets": [ [ 22, 24 ] ], "normalized": [] }, { "id": "1.0alpha7.train.66.ent1_0", "type": "protein-family", "text": [ "PI3K" ], "offsets": [ ...
[]
[ { "id": "1.0alpha7.train.66.coref0", "entity_ids": [ "1.0alpha7.train.66.ent0_0" ] }, { "id": "1.0alpha7.train.66.coref1", "entity_ids": [ "1.0alpha7.train.66.ent1_0" ] } ]
[]
1.0alpha7.train.67
6370284
[ { "id": "1.0alpha7.train.67.sent", "type": "sentence", "text": [ "This defect in the activity of eIF5B in the presence of GMP-PNP could be because hydrolysis of GTP bound to eIF5B is required for the release of eIF5B from assembled 80S ribosomes, for the release of other factors, or for both." ...
[ { "id": "1.0alpha7.train.67.ent0_0", "type": "chemical", "text": [ "GTP" ], "offsets": [ [ 95, 98 ] ], "normalized": [ { "db_name": "pubchem:compound", "db_id": "135398633" } ] }, { "id": "1.0alpha7.train.67.ent1_0...
[]
[ { "id": "1.0alpha7.train.67.coref0", "entity_ids": [ "1.0alpha7.train.67.ent0_0" ] }, { "id": "1.0alpha7.train.67.coref1", "entity_ids": [ "1.0alpha7.train.67.ent1_0" ] }, { "id": "1.0alpha7.train.67.coref2", "entity_ids": [ "1.0alpha7.train.67.ent2_0", ...
[ { "id": "1.0alpha7.train.67.rel0s1.0alpha7.train.67.ent0_0.o1.0alpha7.train.67.ent2_0", "type": "bind", "arg1_id": "1.0alpha7.train.67.ent0_0", "arg2_id": "1.0alpha7.train.67.ent2_0", "normalized": [] }, { "id": "1.0alpha7.train.67.rel0s1.0alpha7.train.67.ent0_0.o1.0alpha7.train.67.ent3_...
1.0alpha7.train.68
19665905
[ { "id": "1.0alpha7.train.68.sent", "type": "sentence", "text": [ "The accumulation of DephrindeltaC-term around axons suggests that Dephrin may bind to DEph." ], "offsets": [ [ 0, 91 ] ] } ]
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[]
[ { "id": "1.0alpha7.train.68.coref0", "entity_ids": [ "1.0alpha7.train.68.ent0_0" ] }, { "id": "1.0alpha7.train.68.coref1", "entity_ids": [ "1.0alpha7.train.68.ent1_0" ] }, { "id": "1.0alpha7.train.68.coref2", "entity_ids": [ "1.0alpha7.train.68.ent2_0" ]...
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1.0alpha7.train.69
10601863
[ { "id": "1.0alpha7.train.69.sent", "type": "sentence", "text": [ "Characterization of substance P binding to human monocytes/macrophages." ], "offsets": [ [ 0, 71 ] ] } ]
[ { "id": "1.0alpha7.train.69.ent0_0", "type": "chemical", "text": [ "substance P" ], "offsets": [ [ 20, 31 ] ], "normalized": [ { "db_name": "pubchem:compound", "db_id": "36511" } ] }, { "id": "1.0alpha7.train.69.en...
[]
[ { "id": "1.0alpha7.train.69.coref0", "entity_ids": [ "1.0alpha7.train.69.ent0_0" ] }, { "id": "1.0alpha7.train.69.coref1", "entity_ids": [ "1.0alpha7.train.69.ent1_0" ] }, { "id": "1.0alpha7.train.69.coref2", "entity_ids": [ "1.0alpha7.train.69.ent2_0" ]...
[]
1.0alpha7.train.70
3475884
[ { "id": "1.0alpha7.train.70.sent", "type": "sentence", "text": [ "Karyopherin beta2 (Kapbeta2, transportin) binds the M9 sequence of human ribonucleoprotein A1 and mediates its nuclear import." ], "offsets": [ [ 0, 126 ] ] } ]
[ { "id": "1.0alpha7.train.70.ent0_0", "type": "protein", "text": [ "Kapbeta2" ], "offsets": [ [ 19, 27 ] ], "normalized": [ { "db_name": "NCBI gene", "db_id": "3842" }, { "db_name": "hgnc", "db_id": "TNPO1...
[]
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