After much exploration , Demner-Fushman et al. ( 2006 ) discovered that it was not practical to annotate PICO entities at the phrase level due to significant unresolvable disagreement and interannotator reliability issues .
automatically identifying health outcome information in medline records
Dina Demner-Fushman Barbara Few Susan E Hauser George Thoma
Of the remaining citations , 275 were used for training and rule derivation , as described in the following sections . After much exploration , Demner-Fushman et al. ( 2006 ) discovered that it was not practical to annotate PICO entities at the phrase level due to significant unresolvable disagreement and interannotator reliability issues . Consider the following segment : This double-blind , placebo-controlled , randomized , 3-period , complete block , 6-week crossover study examined the efficacy of simvastatin in adult men and women ( N = 151 ) with stable type 2 DM , low density lipoprotein-cholesterol 100 mg/dL , HDL-C < 40 mg/dL , and fasting triglyceride level > 150 and < 700 mg/dL .
After much exploration , @@CITATION discovered that it was not practical to annotate PICO entities at the phrase level due to significant unresolvable disagreement and interannotator reliability issues .