Alexander non suonava alcun strumento musicale; nel corso degli anni si avvalse di diversi ragguardevoli musicisti comeKing Oliver, Eddie Lang, Lonnie Johnson, i Mississippi Sheiks e suo cugino Lightnin' Hopkins. ###>Alexander did not play a musical instrument himself, and over the years he worked with a number of other artists including King Oliver, Eddie Lang, Lonnie Johnson, Little Hat Jones, the Mississippi Sheiks, and Lightnin' Hopkins.