Manning passò per 4 touchdown in quella vittoria e vinse nuovamente il premio AFC Offensive Player of the Week, dando ai Colts un record di 10–6 e centrando la wild card dei playoff. ###>Manning threw for 4 touchdowns in the win and was again named AFC Offensive Player of the Week and the win gave the Colts a 10–6 record as well as a wild card spot in the playoffs.