Cimetidin reduziert die renale Clearance von Pramipexol um annähernd 34%, wahrscheinlich durch Hemmung des kationischen sekretorischen Transportsystems der renalen Tubuli. ###>20 Cimetidine reduced the renal clearance of pramipexole by approximately 34%, presumably by inhibition of the cationic secretory transport system of the renal tubules.