Die Vanillinsynthase (VS, ) katalysiert die Spaltung von 3-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA in Vanillin und Acetyl-CoA. ###>Other names in common use include 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase, and (acetyl-CoA-forming).