Thiazi den kunnen de renale excretie van cytotoxica (bv. cyclofosfamide, methotrexaat) doen dalen en hun myelosuppressieve effecten versterken. ###>Thiazides may reduce the renal excretion of cytotoxic medicinal products (e. g. cyclophosphamide, methotrexate) and potentiate their myelosuppressive effects.