Santiago Pinotepa Nacional (Mixteeks: "Ñuu Yoko") is een stadje in de Costa Chica in de Mexicaanse deelstaat Oaxaca. ###>Pinotepa Nacional (formally: Santiago Pinotepa Nacional; in Mixtec, "Ñuu Ñoko", which means Twenty-House Town) is a city and seat of the municipality of the same name, in the Mexican state of Oaxaca.