De enzymen van de citroenzuurcyclus zijn gelegen in het mitochondriale matrix, met uitzondering van succinaat-dehydrogenase, dat aan de binnenmembraan gebonden is. ###>The enzymes of the citric acid cycle are located in the mitochondrial matrix, with the exception of succinate dehydrogenase, which is bound to the inner mitochondrial membrane as part of Complex II.