"Resistance 2" gebruikt ook geen "health bar" meer, er wordt gebruikgemaakt van "automatic regenerative health system", waarbij de spelers uit de vuurlinie moeten blijven om hun gezondheid te herstellen. ###>"Resistance 2" also does not use a health bar in the single player campaign as it did in the first, but instead it uses an automatic regenerative health system, whereby players must keep out of the line of fire in order to recover health.