Hvis behandling med itraconazol, ketoconazol, erythromycin, clarithromycin eller telithromycin ikke kan undgås, skal simvastatin afbrydes under behandlingsforløbet. ###>If treatment with itraconazole, ketoconazole, erythromycin, clarithromycin or telithromycin is unavoidable, therapy with simvastatin must be suspended during the course of treatment.