Clofarabin har høj affinitet til et af de aktiverende phosphorylerende enzymer, deoxycytidinkinase, som overstiger affiniteten til det naturlige substrat deoxycytidin. ###>Clofarabine has high affinity for one of the activating phosphorylating enzymes, deoxycytidine kinase, which exceeds that of the natural substrate, deoxycytidine.