Thiazider kan reducere nyreudskillelsen af cytotoksiske stoffer (fx cyklofosfamid, methotrexat) og forstærke deres myelosuppresive effekt. ###>Thiazides may reduce the renal excretion of cytotoxic medicinal products (e. g. cyclophosphamide, methotrexate) and potentiate their myelosuppressive effects.