sentence: In 1888, Roux published the results of a series of defect experiments in which he took 2 and 4 cell frog embryos and killed half of the cells of each embryo with a hot needle.
modified: At 1888, Rouxes published the result of a series of defects experiment in which he took 2 and 4 cells frogs embryo and killed halves of the cell of each embryos with a hot needles.