  {\it Caenorhabditis elegans} nematode worms are the only animals with the
known detailed neural connectivity diagram, well characterized genomics, and
relatively simple quantifiable behavioral output. With this in mind, many
researchers view this animal as the best candidate for a systems biology
approach, where one can integrate molecular and cellular knowledge to gain
global understanding of worm's behavior. This work reviews some research in
this direction, emphasizing computational perspective, and points out some
successes and challenges to meet this lofty goal.

Neurons and Cognition;Genomics;Quantitative Methods