  Computational biology is on the verge of a paradigm shift in its research
practice - from a data-based (computational) paradigm to an information-based
(cognitive) paradigm. As in the other research fields, this transition is
impeded by lack of a right understanding about what is actually hidden behind
the term "information". The paper is intended to clarify this issue and
introduces two new notions of "physical information" and "semantic
information", which together constitute the term "information". Some
implications of this introduction are considered.

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