  We present measurements of the column densities of interstellar DI, OI, NI,
and H2 made with FUSE, and of HI made with IUE toward the sdO star LSE 44, at a
distance of 554+/-66 pc. This target is among the seven most distant Galactic
sight lines for which these abundance ratios have been measured. The column
densities were estimated by profile fitting and curve of growth analyses. We
find D/H = (2.24 +1.39 -1.32)E-5, D/O = (1.99 +1.30 -0.67)E-2, D/N = (2.75
+1.19 -0.89)E-1, and O/H = (1.13 +0.96 -0.71)E-3 (2 sigma). Of the most distant
Galactic sight lines for which the deuterium abundance has been measured LSE 44
is one of the few with D/H higher than the Local Bubble value, but D/O toward
all these targets is below the Local Bubble value and more uniform than the D/H
distribution. (Abstract abridged.)

Astrophysics