  Known physical mechanisms of temperature dependence anomalies of water
properties were used to explain the regularities in temperature dependence
(TDs) of dynamic, electrical and optical characteristics of biological systems.
The dynamics of hydrogen bonds in bulk and hydrated water affected the
activation energies TDs of ion currents of voltage-dependent channels that
regulate signaling and trophic bonds in the neuropil of the cortical
parenchyma. The physics of minimizing the TD of the isobaric heat capacity of
water made it possible to explain the stabilization and functional optimization
of the thermodynamics of eyeball fluids at 34.5 C and the human brain during
sleep at 36.5 C. At these temperatures, the thermoreceptors of the cornea and
the cells of the ganglionic layer of the retina, through connections with the
suprachiasmatic nucleus and the pineal gland, switch the circadian rhythm from
daytime to nighttime. The phylogenesis of the circadian rhythm was reflected in
the dependence of the duration of the nighttime sleep of mammals on the
diameter of the eyeball and the mass of the pineal gland. The activity of all
the nerves of the eyeball led to the division of the nocturnal brain metabolism
into NREM and REM phases. These phases correspond to two modes of the
glymphatic system - electrochemical and dynamic. The first is responsible for
the relaxation processes of synaptic plasticity and chemical neutralization of
toxins with the participation of water and melatonin. Rapid eye movement and an
increase in cerebral blood flow in the second mode increase water exchange in
the parenchyma and flush out toxins into the venous system. Electrophysics of
clearance and conductivity of ionic and water channels of membranes of blood
vessels and astrocytes modulate oscillations of polarization potentials of
water dipole domains in parietal plasma layers of arterioles and capillaries.

Biological Physics;Fluid Dynamics