  Human Papillomavirus (HPV) has been known as one of the cause of
virus-induced cancer such as cervical cancer and carcinoma. Among other types
of cancer, this type has higher chance in being prevented earlier. The main
idea is to eradicate the virus as soon as it enters the body by marking it with
antibodies; signaling the immune system to dispose of it. However, the
antibodies must be trained to recognize the virus. They can be trained by
inserting an object similar to the virus allowing them to learn to recognize
and surround the inserted object. In response to this, molecular dynamics
simulation was chosen to study the antibody-virus interaction. In this work,
two-dimensional case that involves HPV and immunoglobulin (Ig) was studied and
observed. Two types of objects will be defined; one stands for HPV while
another stands for antibodies. The interaction between the two objects will be
governed by two forces; Coulomb force and repulsive contact force. Through the
definition of some rules and condition, the antibodies' motion was observed.
The influence of antibody concentration, and the antibody's type and their
appearance sequence were observed both quantitatively and visually.
  Keywords: antibody-virus interaction, molecular dynamics, HPV,
immunoglobulin.

Cell Behavior;Biological Physics