  Magnetic resonance imaging (MRI) is a widely used biomedical imaging modality
that derives much of its contrast from microscale magnetic field gradients in
biological tissues. However, the connection between these sub-voxel field
patterns and MRI contrast has not been studied experimentally. Here, we
describe a new method to map subcellular magnetic fields in mammalian cells and
tissues using nitrogen vacancy diamond magnetometry and connect these maps to
voxel-scale MRI contrast, providing insights for in vivo imaging and contrast
agent design.

Medical Physics;Biological Physics;Quantum Physics