  We report for the first time a gamma-ray and multi-wavelength nearly-periodic
oscillation in an active galactic nucleus. Using the Fermi Large Area Telescope
(LAT) we have discovered an apparent quasi-periodicity in the gamma-ray flux (E
>100 MeV) from the GeV/TeV BL Lac object PG 1553+113. The marginal significance
of the 2.18 +/-0.08 year-period gamma-ray cycle is strengthened by correlated
oscillations observed in radio and optical fluxes, through data collected in
the OVRO, Tuorla, KAIT, and CSS monitoring programs and Swift UVOT. The optical
cycle appearing in ~10 years of data has a similar period, while the 15 GHz
oscillation is less regular than seen in the other bands. Further long-term
multi-wavelength monitoring of this blazar may discriminate among the possible
explanations for this quasi-periodicity.

High Energy Astrophysical Phenomena