  High-dimensional data are routinely collected in many areas. We are
particularly interested in Bayesian classification models in which one or more
variables are imbalanced. Current Markov chain Monte Carlo algorithms for
posterior computation are inefficient as $n$ and/or $p$ increase due to
worsening time per step and mixing rates. One strategy is to use a
gradient-based sampler to improve mixing while using data sub-samples to reduce
per-step computational complexity. However, usual sub-sampling breaks down when
applied to imbalanced data. Instead, we generalize piece-wise deterministic
Markov chain Monte Carlo algorithms to include importance-weighted and
mini-batch sub-sampling. These approaches maintain the correct stationary
distribution with arbitrarily small sub-samples, and substantially outperform
current competitors. We provide theoretical support and illustrate gains in
simulated and real data applications.

Methodology;Computation