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pythia_dedupe_mia_0-70000_70010-70025

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the babies, and Winna started to whimper. "That old man trying to run me off the farm?" "It's true, Daddy. They think they gone just sweep in from New York and take it all." Nan picked up Winna and put a chicken bone in her mouth. "That shack you so cozy in?" Juke said to Jim. "I was born in that shack." Jim put up his hands. "We got no intentions of taking over nothing." Sara said, "No thank you. We got no aspirations to take over your life." "Shut up," Juke said to her. "Jim, shut your woman up. It's you I got trouble with." Jim said quietly, "We didn't intend to get in the middle of nothing. We hadn't even heard about any Genus Jackson when we moved in." They were like two shoes dropping, like two creek-filled boots dropping from a dead man's feet to the ground. Genus. Jackson. Juke smiled. He nodded. He understood now. "Thas all right. Thas all right." He slid his chair back behind him and went to his room. When he came back he was holding the twenty-two. "I should a known better than to take in outsiders. At's what got me in trouble before." He cocked the revolver, but returned it to his side. "You think I got it in me to kill? Do you? What did you conclude, after living off my cows' titties for the last six months? What you fixing to report to that Judas George Wilson?" "We don't want any quarrel, Juke." Jim was still seated at the table, his arm around the back of Sara's chair. "We don't plan to take nothing over. We just plan to leave." "We're gonna leave?" Sara asked him, pleading, relieved. Jim nodded. "First thing in the morning, we'll pack up and go." To Sara he said, "It's time to go, with the baby coming." "Hell yes, it's high time," Juke said. "But you ain't waiting till no first thing in the morning. First thing tonight!" Juke sent Nan to help them pack up the shack. Together the three of them carried the pasteboard suitcases to the Ford, the banjo, the bolts of fabric. The dogs followed them in and out of the shack, back and forth to the car. Juke stood on the porch watching them with the gun resting on the railing, drinking his third tumbler of gin, dipping tobacco. Elma put the babies to bed. She didn't hear Sara say to Nan, "We're gonna worry about you, Miss Nan. We'd take you with us if we could." There was no one to hug but Nan, so Sara and Jim both hugged her longer than they'd expected to. When they neared Florence, Sara asked why didn't they stop in at Mr. Wilson's, wouldn't he give them a warm place to stay, and Jim said George Wilson was the last person he wanted to see, and they were probably the last he wanted to see too, given how they'd disappointed him. They had to get out from under him, Jim said. He was glad now they were leaving under cover of night. They had just turned north on the highway when Sara said, "Stop." She put her hand on Jim's elbow. Jim pulled over to the side of the dark road. She said, "Damn damn damn." She slammed the dashboard. "We forgot the gramophone." It was on the porch of the big house, where they'd set it the night Jim learned she was pregnant. "Damn," Jim said. They sat in silence for a moment. Quietly Sara began to cry. "We'll be okay, Georgia peach." "Don't call me that, Jim." She wasn't crying over the gramophone. She was crying for herself, because she had lost a friend, and because she too was spiteful and hateful and full of lies. Sitting in the car at the side of the road, she wasn't pregnant. Her lie had worked—they were leaving the farm, they were moving back home—but there was no satisfaction in it. "God, I hate the South," she said. It wasn't what she meant exactly, but saying it helped her believe it. Later, when her feelings had hardened into something more distinct; after she and Jim had made love in every shantytown between Georgia and New York; after they'd left the Model T in her uncle's driveway, as though they'd just taken it out for a spin; after she told Jim, riding a freight home, and crying real tears, that she'd lost the baby; after they'd arrived in Buffalo and moved in with Jim's mother, who prayed every night at the table for God to sow a seed in Sara's womb; and after a baby didn't come, and didn't come, she'd look back at their time at the crossroads farm and mostly hate Elma, who had two babies at the same time, more than she had milk for, more even than she wanted. Now Jim turned around in his seat and rummaged around in the back. Underneath the stack of suitcases, he lifted a sheet of damask fabric. "Look here." Hidden under it was a crate of Cotton Gin. Sara laughed. Jim reached for two of the jars and gave one to Sara and took one for himself. "I'd say we're square, wouldn't you?" * * * Parthenia Wilson did not send an eye patch but she did send a preacher. He was a small, high yellow man in top hat and tuxedo tails, like some country magician, named Teacup Clifton. He wore the hat to make himself look taller. Standing on the stump of a pine tree the men had felled, he looked, Sterling thought, like a stork on a post. The men had sat on the tree stumps scattered around him, stumps that looked created by God for that purpose, for their wilderness church. "We worship the Lord where we find Him," said Reverend Clifton, "and we find Him everywhere. Hear His voice here in the trees! See His face there in the creek! Brothers, all we must do is open our eyes and ears! _For the Lord hears the cries of the needy, and despises not his prisoners!_ " Some of the men hollered and cried along with him, saying, "Amen," saying, "I hear you, Lord!" Sterling nodded along, but he remained quiet. He did not have a heart for God. God had burned down his house with his family in it. God had hardened his woman's heart against him. God had put him in chains. All the same, he would rather sit on this stump and listen to the man in the top hat than lay down road. It was a Sunday, the first day off in the camp since they'd begun paving the Straight. Sterling's muscles ached in a way that was almost pleasant, the way they ached only after they'd had a chance to rest. The insides of his ankles, from the shackles. His back, his arms, especially the right. Yesterday, the fry cakes and Bibles; today the preacher. They were gifts from the woman he understood to be Freddie's grandmother, George Wilson's woman. And tonight, if talk was true, there would be another gift, this one from the warden. When the preacher turned to the Bible, and spoke of repentance, Sterling did not nod. He did not think of the crimes that had brought him here to the camp, which were not crimes. He did not think of anything. But later, after the preacher left and after the midday meal, the prisoners were sent to piss out near the turkey oaks. The white men were sent first, then the colored. The eight of them stood in a silent row, their ankles chained, draining themselves into the dirt. Then they were sent to wash their hands and faces in the nearly dry creek bed. Sterling could barely see his own face in the creek, let alone God's. But staring off into the surface, staring down the hours left in the day, Sterling did think then of Ketty on Juke's bed, the pearls hailing down on her back. And without meaning to, his mind called up its picture of his parents dropping to their knees, and as they fell their names rose up—Joseph, Lucille—and his eyes stung. He splashed his face with the cold water. He shook his head like a dog. Still squatting, he warmed his numb hands in his armpits. Maybe it wasn't God who'd put him in chains. Maybe it wasn't even white men. Maybe it was one white man. A man who'd seen to it to lynch a Negro on his farm, and then to go on playing daddy to Sterling's child. And there he lived and breathed, just down the Straight, without a care in the world. He wanted to save some hate for the warden but tonight the warden made it hard to hate him. It was Sunday, and to keep them happy and working another week he drove into the camp with two whores in his truck. "Y'all bad boys paving a good road. I brought y'all a reward for being so good." Sterling had been with one of them, the older one, at the county camp
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of ratios of average wages of higher education and secondary school graduates ( ) May 7 Acknowledgements In various ways, numerous researchers from around the globe have provided input to this project, which the authors gratefully acknowledge. The authors would like to thank in particular our international advisors D. Bruce Johnstone, Jan Sadlak and Jamil Salmi for providing their expertise at various stages of the project; it was invaluable for designing the study and conducting the analyses on which this final report is based. Furthermore, the authors would like to acknowledge the support in data research and interpretation provided by the national experts: Martin Unger and Jakob Hartl (Austria), Alison Johnston (UK-England), Jussi Kivistö and Elias Pekkola (Finland), Tamás Kozma, József Temesi and Zsuzsanna Veroszta (Hungary), Cezary Kościelniak (Poland), Luisa Cerdeira (Portugal) and Hwanbo Park (South Korea). Finally, the authors would like to acknowledge the contribution of Lori McElroy, Pamela Marcucci and Ronja Wöstheinrich, who helped conduct background research and improve the national and comparative reports. May 8 Executive Summary Higher education systems have been and are still faced with the task of accommodating growing numbers of students without compromising the quality of education, and without creating undesirable inequalities in access and completion. It is in this context that governments have been adjusting the balance of public and private resources with the goal of achieving more inclusive, more effective, and more sustainable higher education systems. Internationally comparative data sets show that over the last two decades, there has been a general shift towards larger shares of private funding of higher education (see Chapter 2). This shift was achieved largely through raising additional or higher revenues from tuition fees (sometimes termed student contributions ). The concept of cost-sharing is used here to investigate this shift in the balance of public and private funding. Changes in the way costs are shared can take several forms, including the introduction of tuition fees where they did not previously exist or a sharp increase where they already did. They can also involve a reduction or even a freezing of student grants or student loan subsidies (reductions in student aid also constitute an increase in the private funding necessary to cover educational and living costs), but also public policies that encourage enrolment shifts from a heavily subsidised public sector to a much less subsidised, fee-dependent private sector. Looking at cost-sharing from the student perspective, the study focusses on student netcosts, i.e. total costs borne by a student after consideration of tuition fees and compensatory study aid. Even in countries without tuition fees, there is still a substantial amount of cost-sharing because no higher education system covers students' educational and living costs completely. It is surmised that an increase in private costs to students will impact on the behaviour of students. The study also looks at the institutional side of cost-sharing and investigates the changing balance of public and private revenues for higher education institutions (HEIs). From the perspective of HEIs, cost-sharing involves changes to the share of public and private funding as income sources (and thus the respective role of tuition fees, contract income, philanthropic donations, etc. as opposed to state funding). Since a change to this balance affects the relative importance of these sources, it is assumed that it will also change the behaviour of HEIs. Reflecting on the expected impacts on student and HEI behaviours of changes to the cost- sharing balance, the study is framed by four hypotheses as part of a single comprehensive policy analysis model. The hypotheses pick up on key aspects of sustainability, effectiveness and equity of tuition fee policies in higher education. Hypothesis A: As private funding increases, total revenue of HEIs increases. Hypothesis B: As the incentives to earn private funding increase, HEIs become more responsive to student demand. Hypothesis C: Increasing private funding has a negative effect on student demand. Hypothesis D: Increasing private funding affects student choice of how and what to study. To investigate how public and private funding changed and what impact various changes have had on the behaviour of HEIs and students, the authors carried out nine systematic country case studies seven countries from the European Union and two from outside Europe (Austria, Canada, England, Finland, Germany, Hungary, Poland, Portugal and May 9 South Korea). This selection of countries provides a variety of settings in which to investigate the effects. Different countries were chosen according to the following criteria: geographic coverage, economic strength, population size, enrolment numbers, share of students in private higher education, degree of public funding of institutions, changes to private funding, tuition fee policy, and student financial aid provision. It was surmised that the countries with the biggest and most rapid shifts in tuition fee policy would be most interesting for the study, since such shifts could be expected to have greater impact on student and HEI behaviour than a generally stable tuition fee policy. For this reason the cases were split into discontinuity countries (Austria, England, Germany and Portugal) and continuity countries (Canada, Finland, Hungary, Poland and South Korea) for the analysis. The table below presents a summary overview of the country patterns (a detailed overview of the developments can be found in Table 2.2 of the main report). Overview of tuition fee policy change in the period of investigation Share of fee-paying students Increased England 1998 England 2006 Germany 2006/07 Austria 2001 Stayed the same Finland Portugal 2003 (England 2012)* South Korea Canada Decreased Poland Austria 2009 Germany Hungary Average amount paid per student Decreased Stayed the same Increased Note: When no year is given it means that any change was gradual. (England 2012)*: The 2012 tuition fee reform in England is outside the period of investigation of this study, but will be included where data are available and relevant for the purpose of this study. For each case study country, a detailed national report assembles all the elements of the respective cost-sharing system to fully portray the balance between public and private sources of revenues (see National Reports in the main appendix). Main Findings From the analysis, we can make the following observations with respect to how changes in fees affect students and institutions: Higher education data systems remain incomplete The state of the data needed to reasonably assess the state of access to higher education is in many countries fairly poor. In some countries notably Hungary and Poland even obtaining simple information about institutional income sources is nearly impossible. Furthermore, even tracking the level of tuition fees which are actually paid remains difficult in some jurisdictions. This situation presents a constraint for policy-based research on a national level, but makes studies aiming to provide a robust evidence base on a cross-national level even more challenging. The conclusions drawn from this study must be viewed in the light of this fact. May 10 The introduction of tuition fees usually makes the system better-off overall, by increasing the total amount of resources available The study concludes that as private funding for institutions increased, public revenues did not tend to decrease, bringing about an overall increase in institutional income (Hypothesis A, see Chapter 3). The hypothesis was tested using per-student income from public and private sources as a basic indicator. It was found that for most countries and periods of time, the hypothesis can be verified. The few periods of decreasing public perstudent income corresponded to phases of either economic crisis (Canada in the 1990s) or massive enrolment growth (Poland in the 1990s to early 2000s, Austria in the late 2000s). In these specific cases, overall student funding (public and private funding combined) also decreased, i.e. private funding was not used to compensate for this. Most interesting from a policy evaluation perspective are cases in which governments had the goal of bringing about shifts in the cost-sharing balance. Such attempts were made in four of the case study countries: Austria, England, Germany and Portugal. It was shown that from a purely financial point of view, the tuition fee reforms in Germany and Portugal were comparatively modest in scope. Their aim was to provide the system with more funds, without fundamentally altering the predominance of the public sector in higher education funding. The analysis showed that this objective was achieved in Portugal and to some degree in Germany. In Austria, the initial goal of introducing tuition fees appears to have been to bring about a net shift in the cost-sharing balance rather than to increase the funds available to the system. If this is the correct interpretation of the underlying policy goals, then the Austrian reform can be considered a (short-lived) success: the introduction of tuition fees changed the cost-sharing balance, but did not lead to an increase in overall funds for institutions. In England, in contrast to the other three discontinuity countries studied here, the tuition fee reforms successively transformed the system into a model in which private contributions serve as a mainstay of institutional funding of higher education. Particularly the most recent reform from 2012 (which cannot yet be evaluated sufficiently because it is so recent) shows a clear shift to private funding of higher education with liquidity and affordability problems being alleviated through a comprehensive public loan scheme. The resources gained through new fee-derived income are not always invested in ways that would be expected to perceptibly improve the student experience We note that across a number of case studies, the tendency over time was for studentsper-staff ratios to rise, even when institutional income per-student was rising. This is a question of HEI behaviour investigated using Hypothesis B (see Chapter 4). The most extreme example of this was in Canada, where student-teacher ratios rose detrimentally by 20% even as per-student income rose by 40%. Thus, while it may be true that fees make institutions better off, they do not necessarily make for a better student experience, even when per-student income is rising. There are three main reasons why this is so. Firstly, in some cases, new funds are dedicated to expansion rather than
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jury finds the defendant guilty of first degree murder, it necessarily reflects a determination of the defendant's intent. Thus, in Sedeno, the diminished capacity defense would not have permitted the jury to find involuntary manslaughter in the face of the finding of express malice, i.e., express intent, reflected in the first degree murder conviction. In Polley, the questions whether the killing was intentional, accidental, or the product of the negligent use of a firearm, were necessarily resolved against the defendant by the jury's first degree murder verdict. Finally, in Parnell, the jury's finding of felony murder foreclosed the issue of diminished capacity. We believe the present case is governed by the reasoning in Sedeno, Polley, and Parnell. Here, the issue of accidental shooting raised by appellants goes to the intent with which DeJesus shot and killed Zeitsoff. We find *22 the jury's verdict resolved the factual issues raised by appellants against them for two reasons. First, the jury here, unlike the juries in Glenn, Webber, and Ceja, convicted appellants of first degree murder. Thus, the jury found express malice, i.e., the intent to kill and found the murder was premeditated, deliberate and/or willful. Thus, having reached this factual conclusion, the jury could not have found defendants guilty of involuntary manslaughter. (People v. Sedeno, supra, 10 Cal.3d at p. 721.) Thus, as in Polley, the first degree murder conviction necessarily determined the issue raised by the defense of accident. Second, the jury here, as in Parnell, found true the special circumstances alleged by the prosecution, i.e., that the murder was done after lying in wait, and that the murder was committed for financial gain. This, too, demonstrates the jury's factual determination the killing was intentional and deliberate.[14] Obviously, the jury could not have reached this verdict if it gave credence to the claim of an accidental shooting. At most, it would have found second degree murder without the special circumstances. Thus, here, the "omitted instruction was necessarily resolved adversely to [appellants] under other, properly given instructions."[15] Therefore, we hold that to the extent the failure to give the involuntary manslaughter instruction was error, the error was harmless. C. The Accomplice Instruction. (6a) Appellants contend the trial court erred in not giving their requested accomplice instruction in connection with Lohr's testimony. We agree. However, in light of the substantial corroboration of Lohr's testimony and the circumstances which would cause the jury to view his evidence with distrust, we find the error harmless. (7) Section 1111 provides the testimony of an accomplice, i.e., a person who may be charged with the same crime as the defendant, must be *23 corroborated.[16] In order for the witness to be chargeable with the same crime as the defendant: "... it would be necessary for the witness to be considered a principal under the provisions of section 31, which includes `[a]ll persons concerned in the commission of a crime ... whether they directly commit the act constituting the offense, or aid and abet in its commission, or not being present, have advised and encouraged its commission....'" (People v. Hoover (1974) 12 Cal.3d 875, 879 [117 Cal. Rptr. 672, 528 P.2d 760].) To be an accomplice, a witness must have "`"guilty knowledge and intent with regard to the commission of the crime...."'" (People v. Daniels (1991) 52 Cal.3d 815, 866-867 [277 Cal. Rptr. 122, 802 P.2d 906], citations omitted.) The definition of an accomplice "encompasses all principals to the crime including aiders and abettors and coconspirators." (People v. Stankewitz (1990) 51 Cal.3d 72, 90 [270 Cal. Rptr. 817, 793 P.2d 23].) To be an accomplice, one must act "`with knowledge of the criminal purpose of the perpetrator and with an intent or purpose either of committing, or of encouraging, or facilitating commission of, the offense.'" (Id. at pp. 90-91.) The defendant has the burden of proving the witness's status as an accomplice by a preponderance of the evidence. (People v. Fauber (1992) 2 Cal.4th 792, 834 [9 Cal. Rptr.2d 24, 831 P.2d 249]; People v. Sully (1991) 53 Cal.3d 1195, 1228 [283 Cal. Rptr. 144, 812 P.2d 163].) Where the facts are in dispute, the issue is one for the jury. (People v. Stankewitz, supra, 51 Cal.3d at pp. 90-91; People v. Sully, supra, 53 Cal.3d at pp. 1227-1228; People v. Tewksbury (1976) 15 Cal.3d 953, 960 [127 Cal. Rptr. 135, 544 P.2d 1335]; People v. Mayberry (1975) 15 Cal.3d 143, 159 [125 Cal. Rptr. 745, 542 P.2d 1337].) (6b) Here, appellants requested an accomplice instruction which the trial court refused on the basis appellants had not met their burden to prove Lohr was an accomplice by a preponderance of the evidence. While we do not believe Lohr was an accomplice as a matter of law, we do agree with appellants the issue was not free from doubt and should have been determined by the jury. The principal question is whether Lohr had the requisite guilty knowledge and intent relating to the crime. Lohr indicated that, during the days preceding the murder, he had not taken Duncan seriously and had tried to talk him *24 out of killing Zeitsoff. On the day of the murder, he told Duncan he would not be in the room, and, in fact, went into the bathroom when Zeitsoff arrived. To explain his failure to leave the premises completely and his involvement in moving the body after the murder, he indicated he was concerned that if he left the house or did not help in moving the body, he would be kicked out of Duncan's house and/or Duncan would no longer supply him with drugs. On the other hand, Lohr testified he was aware of the plan. He knew DeJesus had been procured by Duncan to perpetrate the murder of Zeitsoff. When asked about his intended involvement in the plot, Lohr's response was, at best, enigmatic: "Q. You had already told Ian, had you not, that you did not want to be involved in a — in a homicide; in a killing? "A. I told him I would not kill [Zeitsoff]. "Q. Did you tell [Duncan] that although you would not pull the trigger, you would be willing to help out? "A. Yes. ".... .... .... .... .... .... .... "Q. Do you have a recollection of telling [Duncan] in what manner you would be willing to help out? "A. In helping get rid of the body." With respect to his reason for wanting to be in the bathroom during the actual commission of the murder, Lohr testified he wanted to be there "[i]n case something went wrong." This suggests his reason was to protect himself, not to avoid participation in murder itself. At trial, he testified he was "not 100%" sure the murder would occur that night, but on prior occasions, he stated he knew it would occur. In any event, he never attempted to warn Zeitsoff of the plot to kill him. After the murder, Lohr helped remove Zeitsoff's possessions from the BMW. He assisted in putting plastic covering over the body and in moving the body to the trunk of the BMW. He also assisted in wiping his and appellants' fingerprints off the car. He accepted $100 from Duncan, though it was not clear if this was for his help in removing the body or to "keep him quiet." *25 We conclude that, based upon all of the facts, the jury could have decided Lohr's testimony indicated he acted "`with knowledge of the criminal purpose of the perpetrator and with an intent or purpose either of committing, or of encouraging, or facilitating commission of, the offense.'" (People v. Stankewitz, supra, 51 Cal.3d at p. 90.) Accordingly, the issues of whether Lohr was an accomplice and the effect on his testimony if he was should have been submitted to the jury. (People v. Sully, supra, 53 Cal.3d at pp. 1227-1228; People v. Mayberry, supra, 15 Cal.3d at p. 159.) However, the error was harmless here for two reasons. First, there was substantial evidence to corroborate Lohr's testimony in the record. (8) "It has been recognized that the failure to instruct on accomplice testimony pursuant to section 1111 is harmless where there is sufficient corroborating evidence in the record...." (People v. Miranda (1987) 44 Cal.3d 57, 100 [241 Cal. Rptr. 594, 744 P.2d 1127], citations omitted.) The corroborating evidence may be entirely circumstantial. (Ibid.; People v. Thurman (1972) 28 Cal. App.3d 725, 730 [104 Cal. Rptr. 804].) The corroborating evidence may be "`slight and entitled to little consideration when standing alone.'" (People v.
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, input logic we_core_i, output logic we_mem_o, input logic [3:0] be_core_i, output logic [3:0] be_mem_o, input logic [31:0] stall_en_i, input logic [31:0] stall_mode_i, input logic [31:0] max_stall_i, input logic [31:0] gnt_stall_i, input logic [31:0] valid_stall_i ); import cv32e40p_pkg::*; import perturbation_pkg::*; `ifndef VERILATOR logic req_per_q, grant_per_q, rvalid_per_q; typedef struct { logic [ADDR_WIDTH-1:0] addr; logic we; logic [ 3:0] be; logic [DATA_WIDTH-1:0] wdata; logic [DATA_WIDTH-1:0] rdata; } stall_mem_t; class rand_gnt_cycles; rand int n; endclass : rand_gnt_cycles class rand_data_cycles; rand int n; endclass : rand_data_cycles mailbox #(stall_mem_t) core_reqs = new (); mailbox #(stall_mem_t) core_resps = new (); mailbox #(logic) core_resps_granted = new (); mailbox #(stall_mem_t) memory_transfers = new (); always_latch begin if (req_core_i) req_per_q <= 1'b1; else req_per_q <= 1'b0; end always_latch begin if (rvalid_mem_i) rvalid_per_q <= 1'b1; else rvalid_per_q <= 1'b0; end always_latch begin if (grant_mem_i) grant_per_q <= 1'b1; else grant_per_q <= 1'b0; end //Grant Process initial begin stall_mem_t mem_acc; automatic rand_gnt_cycles wait_cycles = new (); int temp; int stalls, max_val; #10;//wait at the very beginning while(1) begin @(posedge clk_i); grant_core_o = 1'b0; #1; if (!req_per_q) begin wait(req_per_q == 1'b1); end if ((stall_en_i[0]) && (stall_mode_i == STANDARD)) begin //FIXED NUMBER OF STALLS MODE stalls = gnt_stall_i; end else if ((stall_en_i[0]) && (stall_mode_i == RANDOM)) begin max_val = max_stall_i; temp = wait_cycles.randomize() with{ n >= 0; n<= max_val; }; stalls = wait_cycles.n; end else begin stalls = 0; end while(stalls != 0) begin @(negedge clk_i); stalls--; end @(negedge clk_i); if(req_per_q == 1'b1) begin grant_core_o = 1'b1; mem_acc.addr = addr_core_i; mem_acc.be = be_core_i; mem_acc.we = we_core_i; mem_acc.wdata = wdata_core_i; core_reqs.put(mem_acc); core_resps_granted.put(1'b1); end end end initial begin stall_mem_t mem_acc; automatic rand_data_cycles wait_cycles = new (); logic granted; int temp, stalls, max_val; while(1) begin @(posedge clk_i); rvalid_core_o = 1'b0; rdata_core_o = 'x; #1; core_resps_granted.get(granted); core_resps.get(mem_acc); if ((stall_en_i[0]) && (stall_mode_i == STANDARD)) begin //FIXED NUMBER OF STALLS MODE stalls = valid_stall_i; end else if ((stall_en_i[0]) && (stall_mode_i == RANDOM)) begin max_val = max_stall_i; temp = wait_cycles.randomize() with { n>= 0; n<= max_val; }; stalls = wait_cycles.n; end else begin stalls = 0; end while(stalls != 0) begin @(negedge clk_i); stalls--; end rdata_core_o = mem_acc.rdata; rvalid_core_o = 1'b1; end end initial begin stall_mem_t mem_acc; we_mem_o = 1'b0; req_mem_o = 1'b0; addr_mem_o = '0; be_mem_o = 4'b0; wdata_mem_o = 'x; while(1) begin @(posedge clk_i); #1; req_mem_o = 1'b0; addr_mem_o = '0; wdata_mem_o = 'x; core_reqs.get(mem_acc); req_mem_o = 1'b1; addr_mem_o = mem_acc.addr; we_mem_o = mem_acc.we; be_mem_o = mem_acc.be; wdata_mem_o = mem_acc.wdata; wait(grant_per_q); memory_transfers.put(mem_acc); end end initial begin stall_mem_t mem_acc; while(1) begin memory_transfers.get(mem_acc); wait(rvalid_per_q == 1'b1); @(negedge clk_i); mem_acc.rdata = rdata_mem_i; core_resps.put(mem_acc); end end `endif endmodule A headrest positioning system for automatically adjusting the position of a headrest of a vehicle seat. The headrest can be a power headrest that is part of a power seat system, where the position of the headrest can be preset by a seat occupant with the other positions of the seat in a memory function....http://www.google.com/patents/US20060250016?utm_source=gb-gplus-sharePatent US20060250016 - Automatically adjusting head restraint system A headrest positioning system for automatically adjusting the position of a headrest of a vehicle seat. The headrest can be a power headrest that is part of a power seat system, where the position of the headrest can be preset by a seat occupant with the other positions of the seat in a memory function. The system includes a seat occupant sensing system that senses the position of the seat occupant's head, eyes or other facial features to determine a desired position of the headrest. The system compares the actual position of the headrest to the desired position, and automatically adjusts the position of the headrest to the desired position. In one embodiment, an imaging system determines the position of the seat occupant's head. In another embodiment, the system determines the position of seat occupant's eyes based on the position of the driver side mirror. Images(7) Claims(22) 1. A headrest positioning system for automatically positioning a headrest of a vehicle seat, said system comprising: a headrest sensor for detecting the position of the headrest, said headrest sensor generating a headrest position signal indicative of the position of the headrest; a seat occupant detecting sub-
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THGenerateFloatTypes.h THGenerateComplexTypes.h THGenerateIntTypes.h THGenerateQUInt8Type.h THGenerateQInt8Type.h THGenerateQInt32Type.h THGenerateQTypes.h THLapack.h THStorage.h THStorageFunctions.h THTensor.h THTensorApply.h THTensorDimApply.h THVector.h THHalf.h THTensor.hpp THStorageFunctions.hpp THGenerator.hpp DESTINATION "${ATEN_INSTALL_INCLUDE_SUBDIR}/TH") install(FILES vector/AVX.h ../ATen/native/cpu/avx_mathfun.h DESTINATION "${ATEN_INSTALL_INCLUDE_SUBDIR}/TH/vector") install(FILES generic/THBlas.cpp generic/THBlas.h generic/THLapack.cpp generic/THLapack.h generic/THStorage.cpp generic/THStorage.h generic/THStorageCopy.cpp generic/THStorageCopy.h generic/THTensor.cpp generic/THTensor.h generic/THTensor.hpp generic/THTensorLapack.cpp generic/THTensorLapack.h generic/THTensorMath.cpp generic/THTensorMath.h generic/THTensorRandom.cpp generic/THTensorRandom.h generic/THVectorDispatch.cpp generic/THVector.h # See Note [TH abstraction violation] generic/THTensorFastGetSet.hpp DESTINATION "${ATEN_INSTALL_INCLUDE_SUBDIR}/TH/generic") 2001 Bolivian census The Tenth Census of Bolivia was conducted on 5 September 2001. The population was 8,274,325. References Category:2001 in Bolivia Category:Censuses in Bolivia BoliviaMa’an News Agency As Palestinian leaders prepare to seek UN recognition of statehood in September, there is increasing talk in the US, Israel and elsewhere of disbanding the UN agency for Palestinian refugees, the UN Relief and Works Agency, and handing responsibility for Palestinian refugees to the UN High Commission for Refugees (UNHCR). Some argue UNHCR would resettle the refugees, robbing them of their right to return to their homes. But are these ideas based on a sound understanding of international law and refugee practice? Are they based on a real grasp of the mandates of UNRWA and UNHCR? To set the record straight, Ma‘an turned to UNRWA spokesman Chris Gunness. It is argued that if UNRWA was disbanded and responsibility for Palestinian refugees handed over to UNHCR they would be resettled out of Israel and give up the right of return. Is this the case and if not, what would UNHCR’s role be? Gunness: This is not the case. Palestine refugees are entitled to a just and lasting solution to their plight. This solution would optimally be achieved by the parties and political actors in the context of a negotiated conclusion of the Israeli-Palestinian conflict, and must be in accordance with UN resolutions and international law. It should also be voluntary which means consulting the refugees. There is no merit to claims that the Palestine refugee issue can be addressed by transferring responsibility for Palestine refugees from UNRWA to another agency. Please note two important caveats. First, UNRWA and UNHCR work to distinct mandates, operational and legal definitions, areas of operation, operational realities and constitutive instruments. My responses are consistent with these distinctions and should not be read to assume or imply direct correspondence between the two agencies or their refugee definitions. Rather, I should be understood to draw on the shared premises and common concepts that underpin the precepts applied by UNRWA and UNHCR in their efforts to assist and protect refugees in their respective areas of responsibility. Second, UNRWA is not in a position to speak for UNHCR and does not purport to speak for UNHCR. However, responses to your questions require reference to documents that are posted on UNHCR’s website and are available to the public. My responses are based on UNRWA’s understanding of the plain meaning of these documents as well as the Agency‘s own appreciation of its mission and its knowledge of the system of international law and practice that govern the protection of refugees globally. Established principles and practice – as well as realities on the ground - clearly refute the argument that the right of return of Palestine refugees would disappear or be abandoned if UNHCR were responsible for these refugees. Over decades of international practice, refugee situations have been resolved in three principal ways: local integration, resettlement in third countries and voluntary repatriation. Of these, the voluntary return of refugees to their country of origin has come to be recognised by refugees, states and international agencies as the optimal solution to the plight of refugees. It is equally recognised that for refugees everywhere, a precondition for solutions to refugee situations is the resolution by political actors of the underlying causes of dispute and conflict. This point is made in the 2008 UNHCR document, Protracted Refugee Situations: A discussion paper prepared for the High Commissioner’s dialogue on Protection Challenges. Paragraph 7 of the document observes that "Protracted refugee situations are usually created and sustained by the failure to resolve … differences in a peaceful manner and in a way that respects human rights." Paragraph 9 of this document goes on to note that: "[…] the functions of refugee protection and humanitarian action, vital as they are, can make only a very modest contribution to the prevention and resolution of conflicts that oblige people to live in exile for long periods of time. If those objectives are to be attained, political will and political action are required on the part of states, regional organisations and relevant components of the UN system, including the Security Council and General Assembly." The preface to the UNHCR Handbook on Voluntary Repatriation states that "voluntary repatriation is usually viewed as the most desirable long-term solution by the refugees themselves as well as by the international community. UNHCR‘s humanitarian action in pursuit of lasting solutions to the refugee problems is therefore oriented, first and foremost, in favour of enabling a refugee to exercise the right to return home in safety and with dignity." Chapter 1, paragraph 6 of the UNHCR Handbook states that "the right of refugees to return to their country of origin is fully recognised in international law. The Universal Declaration of Human Rights (1948) established in article 13 (2) that "Everyone has the right to leave any country, including his own, and return to his country." While the Universal Declaration of Human Rights, as a Resolution of the General Assembly, is not a treaty requiring signature or consent, it sets the code of conduct and serves as a point of reference for all universal and regional human rights instruments subsequently adopted." The UNCHR Handbook in its subsequent chapters sets out the obligations of states and of UNHCR in protecting the right of return in the context of voluntary repatriation as well as monitoring, protecting and advocating for the rights of refugees who have returned home. Conclusion 4 of the report to UNHCR’s Executive Committee of 2005, on Local Integration states "Voluntary repatriation, local integration and resettlement are the traditional durable solutions and […] all remain viable and important responses to refugee situations;" "voluntary repatriation, in safety and dignity, where and when feasible, remains the most preferred solution in the majority of refugee situations;" a combination of solutions, taking into account the specific circumstances of each refugee situation, can help achieving long lasting solutions." It is often said that UNRWA perpetuates the Palestinian refugee problem by granting refugee status through the generations and that handing the refugees over to UNHCR would not allow this. Is this the case? This is not the case. As I have already noted, Palestine refugees are entitled to a just and lasting solution to their plight. In the absence of -- and pending the realisation of -- such a solution, it stands to reason that their status as refugees will remain. Questions raised about the passing of refugee status through generations stem from a lack of understanding of the international protection regime. These questions serve only to distract from the need to address the real reasons for the protracted Palestinian refugee situation, namely the absence of negotiated solution to the underlying political issues. UNHCR‘s Handbook on Procedures and Criteria for determining Refugee Status provides in paragraph 184: "If the head of a family meets the criteria of the definition, [for refugee status] his dependants are normally granted refugee status according to the principle of family unity." In effect, refugee families everywhere retain their status as refugees until they fall within the terms of a cessation clause or are able to avail themselves of one of three durable solutions already mentioned -- voluntary repatriation, local integration or resettlement in a third country. Also, Chapter 5 of the UNHCR publication, Procedural Standards for Refugee Status Determination under UNHCR’s Mandate is very clear that in accordance with the refugee’s right to family unity, refugee status is transferred through the generations. According to Chapter 5.1.2 "the categories of persons who should be considered to be eligible for derivative status
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2))$ is a deformation retract of $\Omega^{(1,0)}(n+1,n+1)$, there exists the homotopy equivalent fiber map$$\mathfrak{i}_{SO}:SO_{n+2}(\gamma_{G_{n+1}}^{n+1}\oplus\varepsilon_{G_{n+1}}^{1},TP\oplus\varepsilon_{P}^{2})\longrightarrow\boldsymbol{\Omega}_{n+1}^{(1,0)}=\Omega^{(1,0)}(\gamma_{G_{n+1}}^{n+1},TP\oplus\varepsilon _{P}^{1})$$ over $G_{n+1}\times P$ associated to $i_{n+1}^{SO}$. The image is denoted by $\mathbf{SO}_{n+2}$. Furthermore, $\mathfrak{i}_{SO}$ induces the bundle map $$\mathfrak{B}:\widehat{\gamma}_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell }|_{\mathbf{SO}_{n+2}}\longrightarrow\widehat{\gamma}_{\boldsymbol{\Omega }_{n+1}^{(1,0)}}^{\ell}$$ covering the inclusion $\mathbf{SO}_{n+2}\rightarrow\boldsymbol{\Omega}_{n+1}^{(1,0)}$. \(i) The fiber map $\mathfrak{i}_{SO}$ is a homotopy equivalence. \(ii) The Thom map$$T(\mathfrak{B)}:T\left( \widehat{\gamma}_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell}|_{\mathbf{SO}_{n+2}}\right) \longrightarrow T\left( \widehat {\gamma}_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell}\right)$$ is a homotopy equivalence. Let $SO(TP\oplus\varepsilon_{P}^{1})$ denote the total space of the principal bundle over $P$ associated to $TP\oplus\varepsilon_{P}^{1}$, whose fiber is $SO(n+1)$. Let $(SO(\ell)\times E_{n+1})\backslash SO(n+\ell+1)$ be the Stiefel manifold. Consider the natural actions of $SO(n+1)$ on $SO(TP\oplus \varepsilon_{P}^{1})$ from the right-hand side and on $SO(n+2)$ through $SO(n+1)\times E_{1}$ from the left-hand side, and the natural actions of $SO(n+1)$ on $SO(n+2)$ through $SO(n+1)\times E_{1}$ from the right-hand side and on $(SO(\ell)\times E_{n+1})\backslash SO(n+\ell+1)$ from the left-hand side respectively. Then we can express as$$\begin{aligned} \mathbf{SO}_{n+2} & =SO(TP\oplus\varepsilon_{P}^{1})\underset{SO(n+1)}{\times}SO(n+2)\\ & \text{ \ \ \ \ \ \ \ \ }\underset{SO(n+1)}{\times}((SO(\ell)\times E_{n+1})\backslash SO(n+\ell+1)).\end{aligned}$$ Identify the quotient space $SO(TP\oplus\varepsilon_{P}^{1})/SO(n+1)$ with $P$. Then we have the projection $pr_{P}^{SO}:\mathbf{SO}_{n+2}\rightarrow P$ by forgetting the component $SO(n+2)\underset{SO(n+1)}{\times}((SO(\ell)\times E_{n+1})\backslash SO(n+\ell+1))$, denoted by $\mathfrak{f}$, which is the canonical fiber of $pr_{P}^{SO}$. Let $pr_{S^{n+1}}^{\mathfrak{{f}}}:\mathfrak{f}\rightarrow SO(n+2)/SO(n+1)=S^{n+1}$ be the projection forgetting the component $(SO(\ell)\times E_{n+1})\backslash SO(n+\ell+1)$. Since the last space is $(\ell-1)$-connected,$$(pr_{S^{n+1}}^{\mathfrak{f}})_{\ast}:\pi_{i}(\mathfrak{f})\rightarrow\pi _{i}(S^{n+1})$$ is an isomorphism for $i<\ell$. Hence, we have the following lemma. The homomorphism $(pr_{P}^{SO})_{\ast}:\pi_{i}(\mathbf{SO}_{n+2})\rightarrow\pi_{i}(P)$ is an isomorphism for $i<n+1$ and is an epimorphism for $i=n+1$. Let us define a bundle map$$\mathbf{b}_{\mathcal{T}}:(\pi_{G_{n+1}}^{k})^{\ast}(\gamma_{G_{n+1}}^{n+1})|_{\mathbf{SO}_{n+2}}\longrightarrow TP\oplus\varepsilon_{P}^{1}$$ as follows. We denote an element of $\mathbf{SO}_{n+2}$ and $(\pi_{G_{n+1}}^{k})^{\ast}(\gamma_{G_{n+1}}^{n+1})|_{\mathbf{SO}_{n+2}}$ by $[a,y,h]$ and by $[a,y,h,\mathbf{v]}$ respectively, where $a\in G_{n+1}$, $y\in P$, $\mathbf{v\in}a$ and $h:a\rightarrow T_{y}P\oplus\mathbb{R}$ is an isomorphism preserving orientations and norms. Then we set $\mathbf{b}_{\mathcal{T}}([a,y,h,\mathbf{v])}=h(\mathbf{v)}$. Let us consider the trivialization $(t_{P}\oplus id_{P}\times\mathbb{R})\circ(id_{TP}\oplus\mathbf{k}_{P}^{\backsim}):TP\oplus\varepsilon_{P}^{1}\oplus\nu _{P}^{\ell}\rightarrow\varepsilon_{P}^{n+\ell+1}$. By [@FoldSurg Proposition 3.3], there exists a bundle map$$\mathbf{b}_{\nu}:\widehat{\gamma}_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell }|_{\mathbf{SO}_{n+2}}\rightarrow\nu_{P}^{\ell}$$ such that $(t_{P}\oplus id_{P}\times\mathbb{R})\circ(id_{TP}\oplus \mathbf{k}_{P}^{\backsim})\circ(\mathbf{b}_{\mathcal{T}}\oplus\mathbf{b}_{\nu })\circ t_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}|_{\mathbf{SO}_{n+2}}$ is homotopic to $pr_{P}^{SO}\times id_{\mathbb{R}^{n+\ell+1}}$. Then we have the following lemma. The homomorphism induced from the Thom map of $\mathbf{b}_{\nu}$$$T(\mathbf{b}_{\nu})_{\ast}:\pi_{i+\ell}\left( T(\widehat{\gamma }_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell}|_{\mathbf{SO}_{n+2}})\right) \longrightarrow\pi_{i+\ell}\left( T(\nu_{P}^{\ell})\right)$$ is an isomorphism for $i<n+1$ and is an epimorphism for $i=n+1$. By Lemma 6.2, (6.2), [@SpaAT Section 5, 9 Theorem] and the Thom Isomorphism Theorem,$$T(\mathbf{b}_{\nu})_{\ast}:H_{i+\ell}\left( T(\widehat{\gamma}_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell}|_{\mathbf{SO}_{n+2}})\right) \longrightarrow H_{i+\ell}\left( T(\nu_{P}^{\ell})\right)$$ is an isomorphism for $i<n+1$ and is an epimorphism for $i=n+1$. Since $T((\pi_{G_{n+1}}^{k})^{\ast}(\widehat{\gamma}_{G_{n+1}}^{\ell})|_{\mathbf{SO}_{n+2}})$ and $T(\nu_{P}^{\ell})$ are simply connected, it follows from the Hurewicz Isomorphism Theorem that$$T(\mathbf{b}_{\nu})_{\ast}:\pi_{i+\ell}\left( T(\widehat{\gamma }_{\boldsymbol{\Omega}_{n+1}^{(1,0)}}^{\ell}|_{\mathbf{SO}_{n+2}})\right) \longrightarrow\pi_{i+\ell}\left( T(\nu_{P}^{\ell})\right)$$ is an isomorphism for $i<n+1$ and is an epimorphism for $i=n+1$. According to [@SpaDual], let $\{S^{n+\ell},T(\nu_{P}^{\ell})\}$ denote the set of S-homotopy classes of S-maps $S^{i}\wedge S^{n+\ell}\rightarrow S^{i}\wedge T(\nu_{P}^{\ell})$ $({i}\geq0)$. An element of $\{S^{n+\ell},T(\nu_{P}^{\ell})\}$ represented by a map $\alpha:S^{n+\ell}\rightarrow S^{i}\wedge T(\nu_{P}^{\ell})$ is written as $\{\alpha\}$. Since $\ell\gg n$, $\{S^{n+\ell},T(\nu_{P}^{\ell})\}$ is isomorphic to $\pi_{n+\ell}\left( T(\nu_{P}^{\ell
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amme niiden lausekkeiden poistamista, joilla välittäjille myönnetään sopimusperusteinen suoja, on yksinkertaisesti se, että kilpailulainsäädäntö ei ole asianmukainen väline sopimusosapuolten välisen mahdollisen epätasapainon käsittelemiseen. Nämä kysymykset, kuten keskusteltiin, kun laadimme asetusta (EY) N:o 1/2003, kuuluvat kauppaoikeuden alaan. Automarkkinoiden kaltaisilla kilpailukykyisillä markkinoilla kilpailulainsäädännöllä ei pitäisi puuttua eri sopimusosapuolten väliseen voimatasapainoon. Niin tekeminen olisi tungettelevaa. Meidän on toimittava oikeasuhteisesti, kun puutumme markkinoiden toimintaan. Kuulemisprosessissa saimme selville myös muita, ehkä vähemmän myönteisiä asioita: toisin kuin autojen hinnat korjaustyön keskimääräinen hinta on itse asiassa noussut viime vuosien aikana. Korjaus ja huolto ovat kuluttajille hyvin tärkeitä: ei vain turvallisuuden ja luotettavuuden takia, vaan myös siksi, että korjauslaskut ovat 40 prosenttia auton omistamisen kokonaiskustannuksista. Valitettavasti riippumattomien korjaamojen valmiuksia kilpailla valtuutettujen korjaamojen kanssa haittaavat edelleen monet rajoitukset, mukaan luettuna varaosien ja teknisten tietojen rajallinen saatavuus. Uudistuksellamme pyritään siksi antamaan riippumattomille korjaamoille parempi pääsy varaosiin ja teknisiin tietoihin ja estämään se, että ne suljetaan markkinoilta muilla, uudemmilla käytännöillä. Se johtaa laadukkaampiin korjauspalveluihin ja alempiin hintoihin. Lopuksi, uskon lujasti, että uudet puitteet ovat kuluttajille entistä suotuisammat. Ensisijainen tavoitteemme on lisätä kilpailua jälkimarkkinoilla - korjaus ja huolto - joilla sitä on vähiten? Vaikka ajoneuvojen valmistajien kaupallinen asema saattaa olla vahva välittäjiin verrattuna, ne taistelevat raivokkaasti toistensa kanssa, ja siksi nyt ei tarvita poikkeusta, tällaisia sopimuksia koskevan kilpailun säilyttämiseksi, alakohtaisia sopimuksia koskevasta ryhmäpoikkeusasetuksesta, jonka komissio antoi äskettäin ja joka myös tulee voimaan tämän kuukauden lopussa. Todellakin, komissio ja erityisesti minun yksikköni, kilpailun pääosasto, valvovat alaa hyvin huolellisesti, eikä pitäisi olla epäilystäkään komission päättäväisyydestä valvoa kilpailusääntöjä ja ryhtyä tarvittaviin toimiin, jos huomataan joitakin vakavia rikkomuksia tai puutteita. Othmar Karas Arvoisa puhemies, arvoisa komission jäsen, hyvät kollegat, olemme nyt kuulleet paljon. Tällä suullisella kysymyksellä ja päätöslauselmalla halusimme antaa autojen välittäjille ja pienille ja keskisuurille yrityksille äänen, koska komissio ei ole kiinnittänyt viime vuosina tarpeeksi huomiota tähän ääneen. Kuulemisen aikana ennen kaikkea autojen välittäjät ilmaisivat huolta ja epävarmuutta epätasa-arvoisesta kohtelusta valmistajiin verrattuna. Oikeudellinen epävarmuus otettiin esiin kuten myös kilpailun väheneminen pienten autonvälittäjien kohtaamien ongelmien takia. Emme kuitenkaan ole saaneet vastausta. Pyydän teitä - minuuttia vaille 12 - käyttämään 21 päivää ennen toukokuun 26. päivää sisällyttääksenne päätöslauselman, jonka parlamentti antaa huomenna, asetukseenne, jotta voitte tulla autonvälittäjiä puolitiehen vastaan muuttamatta suuntaa, jonka komissio haluaa valita. Olkaa hyvä ja suhtautukaa parlamenttiin ja autonvälittäjien huoliin vakavasti ja sisällyttäkää heidän huolensa ja pienten ja keskisuurten yritysten huolet asetukseen. Olle Ludvigsson S&D-ryhmän puolesta. - (SV) Arvoisa puhemies, haluaisin korostaa neljää kysymystä tässä keskustelussa. Ensinnäkin, on olemassa valitettava pyrkimys asettaa autoteollisuuden pienet ja suuret yritykset toisiaan vastaan. Niillä on tietyssä määrin erilaiset edut, mutta meidän on ensisijaisesti keskityttävä luomaan sääntelyjärjestelmä, jonka avulla ne voivat tehdä tehokkaasti yhteistyötä. Toiseksi, on hyvin myönteinen merkki, että uusien autojen markkinoiden kilpailu on parantunut viime vuoden aikana. Tämä on hyvä esimerkki siitä, että mitkään markkinat eivät ole mahdottomia ja että pitkällä aikavälillä on mahdollista saada paljon aikaan kilpailua vahvistavilla toimenpiteillä. Toivottavasti jälkimarkkinoilla kehitys on tulevaisuudessa yhtä myönteistä. Kolmanneksi, on tärkeää, että komissio seuraa hyvin aktiivisesti kehitystä uusien autojen markkinoiden kilpailun osalta. Sitä pitäisi valvoa jatkuvasti. Kaikkien asianosaisten osapuolten pitäisi saada mahdollisimman pian lopulliset tiedot säännöistä, joita sovelletaan vuoden 2013 kesäkuusta alkaen. Neljänneksi, meidän pitäisi tehostaa keskustelujamme siitä, miten aiomme vaihtaa vihreisiin, ympäristön kannalta suotuisampiin autoihin. Se on ehdottomasti olennaisen tärkeä prosessi. Toisaalta, kilpailusääntöjen on oltava joustavia niiden tukien osalta, joita tarvitaan, jotta sähköajoneuvot ja muut ympäristön kannalta suotuisat vaihtoehdot voivat vakiintua markkinoilla, ja toisaalta säännöillä on varmistettava, että ympäristön kannalta suotuisat autot eivät joudu epäedulliseen asemaan vähittäisalalla tai jälkimarkkinoilla. Cristian Silviu Buşoi ALDE-ryhmän puolesta. - (EN) Arvoisa puhemies, auton hankintaa ja omistamista pidetään yhtenä kotitalouksien suurimpana menoeränä. Kilpailupolitiikan perimmäinen tavoite on varmistaa kuluttajien valinnanvapaus ja tuotteiden saatavuus alemmilla ja koht
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isoleucine, is tightly controlled by a complex interplay of transcriptional regulation and feedback inhibition mechanisms \[[@pcbi.1005371.ref018], [@pcbi.1005371.ref019]\]. In the other direction, the identification of specific regulatory programs that are utilized to avoid the accumulation of toxic intermediates is a promising avenue to discover novel endogenous antibiotics that allow to more efficiently kill pathogens through self-poisoning. In this work, we use dynamic optimization to study how the toxicity of intermediates influences regulatory programs that control metabolic pathways. For such pathways, our optimization approach predicts a more focused regulation of enzymes that occur upstream of toxic intermediates. Moreover, there is a strong tendency of transcriptional regulation to target enzymes that are efficient in terms of catalytic activity as well as substrate affinity and possess less toxic upstream intermediates. Especially a focus on transcriptional regulation of efficient enzymes is surprising since it is often assumed that rate-limiting steps, which are catalyzed by inefficient enzymes, are key points of pathway control \[[@pcbi.1005371.ref020], [@pcbi.1005371.ref021]\]. We validate our prediction through a detailed examination of the interplay between enzyme efficiency as well as transcriptional control in *Escherichia coli* and a study of the relationship between regulatory effort as well as intermediate toxicity in the metabolic networks of more than 5000 prokaryotes. Moreover, we illustrate the usefulness of our approach through a detailed investigation of the influence of intermediate toxicity on the production of endogenous toxic metabolites in lipopolysaccharide metabolism. Materials and methods {#sec002} ===================== Modeling approach {#sec003} ----------------- To model the toxicity of intermediates, we extended the optimization problem formulated by Wessely et al. \[[@pcbi.1005371.ref010]\] with the explicit consideration of toxicity of individual intermediates through concentration thresholds for each metabolite *β*~*i*~ ([Fig 1A](#pcbi.1005371.g001){ref-type="fig"}). The underlying ordinary differential equation system (ODE) describes a linear pathway converting a substrate *S* via five enzymatic reactions into a product *P* (see [S1 Text](#pcbi.1005371.s001){ref-type="supplementary-material"}). The selection of a five step linear pathway was made since it provides a good trade off between long and short linear pathways and is also the mean length of the defined linear pathways based on the listed pathways in MetaCyc \[[@pcbi.1005371.ref024]\]. Nevertheless, we obtain comparable results also for shorter and longer pathway lengths (see [S2 Text](#pcbi.1005371.s002){ref-type="supplementary-material"}). ![(A) Model of a linear pathway used for optimization. The substrate **S** is converted to a product **P** via five reactions catalyzed by enzymes with the concentration *e*~*j*~(*t*) with kinetic parameters *k*~*cat*~ and *K*~*m*~ and four intermediates *X*~*i*~ with concentration thresholds *β* that indicate their toxicity. The product **P** is diluted by *v*~*g*~ (dilution rate). (B) Objective function of the optimization problem. The objective function minimizes the regulatory effort of *e*(*t*) (green areas) and the initial concentration of enzymes *e*(0).](pcbi.1005371.g001){#pcbi.1005371.g001} While the substrate of the pathway is assumed to be constant in concentration, the product undergoes a drain e.g. by growth or other environmental changes *v*~*g*~(*t*), which vary over time: $$\begin{aligned} {v_{g}\left( t \right)} & {= \begin{cases} {g_{1},} & {t < 10} \\ {g_{2},} & {10 \leq t < 20} \\ {g_{3},} & {20 \leq t \leq 30} \\ \end{cases}} \\ \end{aligned}$$ The dilution is balanced by the regulation of the concentration of enzymes that catalyze the conversion of metabolites modeled as irreversible Michaelis-Menten kinetics with the parameters *k*~*cat*~ and *K*~*m*~. As discussed previously \[[@pcbi.1005371.ref010]\], considering an outflow of the product through growth is conceptually identical to a change of product demand, but can be formulated more conveniently in the optimization approach. Results were found to be robust against variations in the preset changes of dilution rate *v*~*g*~(*t*) (see [S2 Text](#pcbi.1005371.s002){ref-type="supplementary-material"}). Therefore the same changes in dilution rate *v*~*g*~(*t*) like in Wessely et al. \[[@pcbi.1005371.ref010]\] were used for all optimization runs. The toxicity of intermediates is simulated as constraints on the concentration of the metabolites: $$0 \leq x_{i}\left( t \right) \leq \beta_{i}$$ A biological interpretation of the toxicity threshold used in the optimization is, for instance, the half inhibitory concentration (IC50) of a metabolite, that is, the concentration at which half of a bacterial population is inhibited in its growth. In the objective function we minimize two factors: the regulatory effort and protein costs. The regulatory effort is modeled as the deviation from initial enzyme concentrations and protein costs by the initial concentration of enzymes. Both objectives are weighted with the factor *σ*. Hence, the following objective function: $$\begin{aligned} {F\left( e \right)} & {= \min\limits_{e_{1{(t)},...,e_{5}{(t)}}}\sum\limits_{j = 1}^{5}\left( {\int\limits_{0}^{T_{max}}\left( \sigma \cdot \underset{\text{abundance}}{\underset{︸}{e_{j}\left( 0 \right)}} + \underset{\text{regulation}}{\underset{︸}{\left( e_{j}\left( t \right)-e_{j}\left( 0 \right) \right)^{2}}} \right)dt} \right)} \\ \end{aligned}$$ is used to determine the optimal regulatory program. The factor *σ* models the costs for the whole pathway and not of single enzymes. In previous studies \[[@pcbi.1005371.ref014], [@pcbi.1005371.ref016]\] we discovered that varying synthesis costs within the pathway can influence the regulatory strategy, but is neglected here to focus on the impact of toxic intermediates. The model consists of several parameters with arbitrary units ([Table 1](#pcbi.1005371.t001){ref-type="table"}). The time-dependent concentrations of the five enzymes are used as control variables during the optimization. The simulation time span is set to 30 arbitrary time units and has no influence on optimization results (see also \[[@pcbi.1005371.ref015]\]). Parameters connected to toxicity (*β*) and kinetics (*k*~*cat*~,*K*~*m*~) are tested for their influence on optimal regulatory programs for two values of *σ* corresponding to high and low enzyme costs, respectively. To test the influence of toxicity and kinetic parameters, we performed 1000 runs in which their values were chosen randomly from the intervals indicated in [Table 1](#pcbi.1005371.t001){ref-type="table"}. 10.1371/journal.pcbi.1005371.t001 ###### Parameter and variable overview. ![](pcbi.1005371.t001){#pcbi.1005371.t001g} Factor Value Description ---------------- --------------------------------- ------------------------------------------ *e*~*j*~ \[0,∞\] enzyme concentration (control variable) *σ* $\frac{1}{3}$ or $\frac{1}{30}$ weight of enzyme cost *T*~*max*~ 30 timespan of optimization *k*~*cat*,*j*~ \[0,2\]\* turnover number *K*~*m*,*j*~ \[0,2\]\* inverse substrate affinity *β*~*i*~ \[0,4\]\* threshold of intermediate concentrations A star \* indicates that the parameters are sampled from the indicated range. Dynamic optimization and analysis of simulation results {#sec004} ------------------------------------------------------- The above described optimization problem has time dependent and continuous decision (*e*(*t*)) and state variables (metabolite concentrations), and hence has to be solved using dynamic optimization. Similar to previous works \[[@pcbi.1005371.ref010], [@pcbi.1005371.ref014], [@pcbi.1005371.ref016]\], we used a quasi-sequential approach with the extensions of \[[@pcbi.1005371.ref022]\] to handle approximation errors and moving finite elements. Since this method is gradient-based, the optimization was repeated one hundred times for each random parameter set using random initializations to avoid local optima. For each random parameter set, we only considered the solution with the best objective function value. To investigate the influence of kinetic and toxicity parameters on optimal regulatory programs, 1000 randomly distributed parameter samples were obtained as Sobol-sequences \[[@pcbi.1005371.ref023]\], which are values quasi-randomly distributed in the parameter space. In contrast to randomly chosen parameters sets, values obtained from a Sobol-sequence are maximizing the distance to each other in the parameter space. This leads to an optimal coverage of the parameter space and therefore less parameter tests are needed. We are specifically interested in the relationship between regulatory effort, measured as deviation of enzyme time-courses from initial enzyme concentrations, and toxicity as well as kinetic parameters. To investigate this relationship, we partitioned the randomized parameters sets depending on the amount of regulatory effort at the individual pathway positions. Subsequently, we compared the distribution of toxicity parameters *β* and enzyme efficiency $k_{\textit
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have some bad news about your car." "Which one?" "I think it's best you see for yourself." "I'll let them know we're on our way." "What do you know about this guy?" "He's another c.I." "Peter leans on him when neal's not around." "Really?" "We should talk to him." "No, let's let it play out." "Let's see where he leads us." "So, Thursday has a view, huh?" "To say Thursday has a view... is like saying the hubble telespe... has a magnifying glass." "It ithe most spectacular cityscape... our fair city has to offer." "Really?" "I have to go now." "Ay." "Are you gonna watch "moon landing..." "factr fiction?"..." "No." "Oh." "Then it leaves with me." "It was nice to see you, Mrs. suit." "Nice to see you, too, moz." "Thanks for the vino." "It was neal's." "Looks like our c.I. 'S left the building." "You want us to follow him or stay here?" "We should follow him." "We do both." "My guys stay and monitor the house." "We'll follow the miniature Caffrey." "I guess it's "put your c.I. To work" day." "This way." "Pretend you know me." "Give me a reason." "I've given your sweetheart safe passage, and in about two minutes, we're gonna clear his name." "They got to be talking about Burke and Franklin." "Excuse me, guys, I got to take this." "This is neal." "Hey." "Are you with deckard?" "Yeah, yeah." "Are you there, sir?" "I am." "Who that?" "Tell him it's bancroft." "It's bancroft." "Diana should be with stan volker." "Yeah." "Uh-huh." "That's correct." "Give me the phone." "Look, I think deckard wants to speak with you." "Caffrey, you still there?" "Did you lose him?" "It's deckard, sir." "Deckard?" "Put Caffrey back on." "Yes, sir." "I'm back." "Okay." "Have you ever run a prisoner's dilemma?" "I've been in one." "Well, now's your chance to run it on a U.S. marshal." "You clear on what to do?" "Crystal clear." "Thank you, sir." "What's going on?" "Just follow my lead." "$tan 1 was stolen earlier today... and apparently taken on quite a joy ride." "They thought they could bring it here for parts." "What are they doing in there?" "I think you know what they're doing in there." "That's it." "Who did this?" "We have them in custody, Mr. volker." "Don't worry." "Well, they're gonna pay." "Just need your signature..." "If you could read over this statement for me." "I think you'll find everything's in order." "Volker's cutting a deal with the FBI." "He's selling you out." "Yep, there it is..." "a signed confession." "See, once you showed up at volker's office, he knew it was only a matter of ti before you turned on him." "He made a deal." "Come on, deckard." "Don't make it harder than it is." "There is one more thing." "What is this all about?" "Deckard says you paid off an FBI Agent... to intimidate and kill witnesses in federal trials." "You're looking at 25 to life..." "Unless you start talking." "Deckard came up with the whole thing." "What do you want to know about him?" "Give it up." "Stay back!" "Hands up, deckard!" "It's over." "Put the gun down on the ground!" "You realize the grief you caused me with bancroft... when you fled?" "Being on this side of a manhunt... isn't all peaches and dandelions, is it?" "Beats being led away in cuffs." "Good working with you, deckard." "How'd it go?" "They've cleared Franklin of all charges." "Bancroft's reinstating him into the white collar division." "That's great work, everyone." "Let's get some rest." "Neal..." "Good work." "Thank you." "I'll be headed home, too." "Won't be going to the Powell today, 'cause, you know, it's outside my radius." "Please?" "Thanks for playing last night, moz." "Oh, the follow-the-leader stuff?" "That was child's play." "The reason I'm calling now... is because I've obtained some information since then." "What'd you find?" "I know who Kate called from the plane." "It was the FBI Agent who set up the deal between you and Kate." "Garrett Fowler." "Now I need to find him." "Caffrey!" "I'll get right back to you." "Sir." "Come here." "You planning on seeing this?" "Well, yeah, I was, but, you know, it's out of my range and..." "Uh-huh." "I've wanted to see this thing since it opened." "Let's go." "You know, from the moment I met you," "I could tell you're a man of refined tastes." "Oh, I know, hon." "I'll be home. 15 minutes, tops." "Oh, I can't wait, either." "Just a few hours sleep, and I'll be yours all day..." "And night."My First (and perhaps only) Blogging Award! My friend Susie has nominated me for the Very Inspiring Blogger Award. She is so sweet. Her blog is SusieShy45, and it always a joy to read: so please check it out. This is my second blogging host site, and I love WordPress: I have made so many friends and found so many blogs to read some days I can’t keep up. I started a blog because I want to write. Good reason, right? What I have found a vivid community of bloggers that I never expected. They are supportive, funny and very necessary to me. I thank everyone who reads my blog, and hope that I will continue to interest, entertain or inspire you (whatever it takes to keep you reading 😉 ) There are some rules I need to follow to accept this award, the first was taken care of by thanking Susie (which I would have done anyway). The second is that I need to list the rules and display the award (as if I wouldn’t!), the third is share seven facts about myself (forthcoming) and the fourth is that I nominate 15 fellow bloggers for the award (also forthcoming). Seven Facts about me: 1) In my 20s I was terribly depressed that I would never write anything to measure up to War & Peace 2) I have an odd combination of OCD and ADD, which makes me both compulsive and a scatterbrain ( I am not diagnosed, just have certain tendencies that way that have been generally noticed by most people I come in contact with) 3) I love anything that has four legs and a tail, and, fortunately, they love me back 4) I am currently unemployed and working to get a certification in Medical Admin Assistant to find a grown-up career 5) I really enjoy helping people 6) I was a farmer 7) I no longer care if I write War & Peace, I happy to write on my two blogs and see what comes I chose my bloggers for different reasons. Some are inspiring for the quality and quantity they write. It can be difficult to post several times a week and still be interesting and relevant. These bloggers do that. Some I picked for what they write. Opening a vein and spilling your life’s blood for the world to see is hard, and it is inspiring how unflinchingly these bloggers do that.Q: Loading images in array Java Which is the best way to store images in an array? I'm using ImageIO and I now wish to store them in an array. A: PixelGrabber is what you want. Image img = null; try { img = ImageIO.read(new File("img.png")); } catch (IOException e) { e.printStackTrace(); } int w = img.getWidth(null); int h = img.getHeight(null); int[] pixels = new int[w * h]; PixelGrabber pg = new PixelGrabber(img, 0, 0, w, h, pixels, 0, w); try { pg.grabPixels(); } catch (InterruptedException e) { System.err.println("interrupted waiting for pixels!"); return; } if ((pg.getStatus() & ImageObserver.ABORT) != 0) { System.err.println("image fetch aborted or errored"); return; } for (int i = 0; i < pixels.length; i++) System.out.println(pixels[i]); A: If you read the whole images in memory, you can
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-09-00012} ----------------------------------------------- ### 5.2.1. Deep Learning Used for Antibody Lead Optimization {#sec5dot2dot1-antibodies-09-00012} A successful application of deep learning within the domain of interaction prediction comes from a sequence-based approach proposed to optimize an existing antibody candidate by Mason et al. \[[@B35-antibodies-09-00012]\]. Rather than using a public domain dataset, the authors generate a relatively small number of variants (5 × 10^4^) of an existing therapeutic antibody by introducing mutations to the H3 regions of the CDR and screening the variants for binding against a target antigen. The H3 sequences, labeled as binding or non-binding, were used as input to long-term-short-term recurrent neural networks and convolutional neural networks which were trained to predict the binding label of the sequences. Trained networks were then used to filter a computationally generated set of 7.2 × 10^7^ candidate sequences to 3.1 × 10^6^ predicted binders. Experimental testing showed that 30 out of 30 randomly selected predicted binding sequences bound specifically to the target antigen, with one of the thirty exhibiting a three-fold increase in affinity. The significance of this method is highlighted by the comparative analysis with a structure-based approach. The authors demonstrate that the number of new binding sequence suggestions generated by the structural modeling software is orders of magnitude smaller than the actual expected binding sequence space and that the free energy estimation of the modelled structures could not be used as a reliable classifier of binding activity. While structure-based methods have the potential to represent richer features for a given input, sequence-based methods benefit from more data availability due to developed experimental methods such as next-generation sequencing. ### 5.2.2. Ens-Grad {#sec5dot2dot2-antibodies-09-00012} Another sequence optimization algorithm, Ens-Grad, uses an ensemble of neural networks and gradient ascent to optimize an H3 seed sequence \[[@B36-antibodies-09-00012]\]. Briefly, Liu et al. report training an ensemble of six neural networks (five convolutional) using experimental phage display data generated from panning experiments. Panning experiments approximate enrichment in binding affinity by subjecting a set of H3 sequences bound to phages to a binding competition where non-binders are washed away and binders are kept for subsequent rounds \[[@B37-antibodies-09-00012]\]. Several different models with varying architectures were trained using either a means squared error loss for regression of enrichment, or a binary cross entropy for classification of H3 CDRs that were successively enriched in rounds of panning. After fitting the ensemble of neural networks, the authors use gradient ascent to optimize input seed sequences. Contrary to gradient descent, which is generally used to modify neural network weights so as to minimize a loss function such as classification error, gradient ascent is used in this case to modify the input sequence so as to maximize the output. The authors suggest that the use of an ensemble of several neural networks allows for optimization to take controlled paths by optimizing with respect to different network outputs. Using this optimization protocol, the authors were able to generate sequences with greater enrichment than both seed sequences and sequences within the training dataset. This significant result suggests that the neural network models were able to extrapolate beyond input training data, possibly by learning high level representations of what determines enriched binding. Additionally, the authors demonstrate superior performance using a gradient ascent method compared to more common generative models such as variational auto-encoders and genetic algorithms. However, it is unclear whether or not the difference between these methods is attributable to the style of optimization, or to the difference in the architecture of the network (e.g., number of layers or layer sizes). Similar to the method developed by Mason et al. \[[@B35-antibodies-09-00012]\], this method completely circumvents the need for structural data which is significantly more difficult to acquire. However, it is highly unlikely that these methods generalize well across target antigens. In each method the network is fit to data points derived from a single target antigen and therefore applying this method to a different target would require extensive wet-lab testing to generate the training data and refit the model. ### 5.2.3. DeepInterface {#sec5dot2dot3-antibodies-09-00012} DeepInterface is a structure-based method which aims to classify protein complexes in their docked conformational state as either true or false binders \[[@B38-antibodies-09-00012]\]. The input to the network is a voxel grid constructed from a fixed-size box placed around the interface. To handle rotation ambiguity, the authors align the vector between the structures center of mass to one of the three coordinate axes. The network itself is composed of four convolutional layers followed by batch normalization and rectified linear units. To transform the voxel space into a one-dimensional vector and subsequently into a prediction of binding, global average pooling is applied to the voxel space followed by two fully connected layers. Of note here is the generation of negative data used to train the network. Negative examples in this case refer to any structures which are not true binders. Using negative examples is a vital step in classification, as the network must be exposed to some form of negative input for successful training. To generate these negative examples, the authors use a fast-Fourier transform (FFT)-based docking algorithm, ZDOCK, to select incorrect docking solutions from the set of sampled conformations \[[@B13-antibodies-09-00012]\]. Representation of the protein interface as a voxel grid is an intuitive yet problematic strategy. Firstly, the input size of the network restricts the voxel space to a single size. The authors overcome this by limiting the size of the interfaces passed into the network to those small enough to fit into the bounded grid space. Secondly, a rotational ambiguity problem arises due to the absence of a common axis across all interfaces. Similar voxel methods used for 3D objects can usually take advantage of an implied gravity vector to eliminate ambiguity across an axis. Handling ambiguity between the remaining axes can be done using a randomly rotated version of the input or by implementing rotational pooling into the network architecture. However, these methods are impractical for more than two dimensions as the number of possible rotations needed grows exponentially. Despite these limitations, DeepInterface achieves 75% classification accuracy on benchmark datasets, demonstrating viability in this classification task Due to the differences previously mentioned between antibody-antigen interfaces and general PPIs, it is not clear that the model here presented would be capable of avoiding false positive classification. This problem may give rise to out-of-distribution errors, which arise when the underlying training dataset is not representative of its real-world use case. However, except for the bounding voxel space size, the model architecture and input structure presented within DeepInterface is somewhat agnostic to the type of interface evaluated. It should be noted, however, that the model's reliance on spatial arrangement of the interface area should not hinder its applicability towards antibody--antigen interfaces, which possess non-discernable differences in shape complementarity \[[@B6-antibodies-09-00012]\]. ### 5.2.4. MaSIF-Search {#sec5dot2dot4-antibodies-09-00012} The MaSIF approach comes out of the growing field of geometric deep learning. Starting from a mesh representation of a protein surface, a patch is created by selecting a point on the mesh and all neighboring surface points within a defined geodesic distance \[[@B39-antibodies-09-00012]\]. Each of the surface points is annotated with geometric and chemical features which describe degrees of curvature, concavity, electrostatic potential, hydrophobicity and hydrogen bond potential. The patch is down-sampled into a grid of 80 bins (5 radial × 16 angular). Each bin contains the statistical mean of the feature attributes of the points which are assigned to the corresponding bin. The 80 bins, indexed by polar and angular coordinates, are passed as input into a set of geodesic convolutional filters to generate a one-dimensional descriptor of the protein surface. Rotational max-pooling is used to overcome angular ambiguity. The one-dimensional descriptor is then refined by a fully connected layer. The remaining architecture is regarded as application-specific, which expresses the ability to use the 1D descriptors as input into an application specific model. To train an application specific model for interaction prediction, a modified version of the triplet loss function is used, which minimizes the Euclidean distance between the 1D descriptors of an anchor (a binding protein patch) and a positive (a complimentary patch to the anchor), and maximizes the distance between the anchor and a negative (a randomly chosen, non-complementary surface patch to the anchor). The authors deem two surface patches from two separate proteins to be positive pairs if the patch centers are within a small distance from one another at the protein--protein interface. To measure the model's performance, the authors classify interacting vs. non-interacting pairs and report an area under the curve of the receiver operating characteristic (ROC AUC) of 0.99 when using geometric and chemical features. The authors further evaluate the model's performance on different subsets of the data by creating subsets of low, high and very high interface complementarity. It is interesting to note that, as expected, the classification performance of the model drops to 0.81 ROC AUC using both geometric and chemical feature sets on the low shape complementary subset and further to 0.73 and 0.75 when using only the geometric and chemical features on this subset, respectively. MaSIF search is trained on a mix of antibody--antigen and protein--protein interfaces with no distinction between the two. As mentioned previously, antibody--antigen interactions exhibit a similar shape complementarity to that of other protein--protein interfaces \[[@B6-antibodies-09-00012]\].
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country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TEX').property('city', 'Telluride').property('state', 'CO').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YXT').property('city', 'Terrace').property('state', 'BC').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TXK').property('city', 'Texarkana').property('state', 'AR').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TVF').property('city', 'Thief River Falls').property('state', 'MN').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YTH').property('city', 'Thompson').property('state', 'MB').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YQT').property('city', 'Thunder Bay').property('state', 'ON').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YTS').property('city', 'Timmins').property('state', 'ON').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'OOK').property('city', 'Toksook Bay').property('state', 'AK').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TOL').property('city', 'Toledo').property('state', 'OH').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TOP').property('city', 'Eureka').property('state', 'KS').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YYZ').property('city', 'Toronto').property('state', 'ON').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YTZ').property('city', 'Toronto').property('state', 'ON').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YTO').property('city', 'Toronto').property('state', 'ON').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TVC').property('city', 'Traverse City').property('state', 'MI').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TTN').property('city', 'Trenton').property('state', 'NJ').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TRI').property('city', 'Tri-City Airport').property('state', 'TN').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TUS').property('city', 'Tucson').property('state', 'AZ').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TUL').property('city', 'Tulsa').property('state', 'OK').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TUP').property('city', 'Tupelo').property('state', 'MS').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TWF').property('city', 'Twin Falls').property('state', 'ID').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'TYR').property('city', 'Tyler').property('state', 'TX').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'UNK').property('city', 'Unalakleet').property('state', 'AK').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'EGE').property('city', 'Vail').property('state', 'CO').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YVO').property('city', 'Val-d&#39;Or').property('state', 'PQ').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'VDZ').property('city', 'Valdez').property('state', 'AK').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'VLD').property('city', 'Valdosta').property('state', 'GA').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YVR').property('city', 'Vancouver').property('state', 'BC').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YYJ').property('city', 'Victoria').property('state', 'BC').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'VCT').property('city', 'Victoria').property('state', 'TX').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'VIS').property('city', 'Visalia').property('state', 'CA').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'YWK').property('city', 'Wabush, Labrador').property('state', 'NF').property('country', 'Canada').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'ACT').property('city', 'Waco').property('state', 'TX').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'ALW').property('city', 'Walla Walla').property('state', 'WA').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'IAD').property('city', 'Washington DC').property('state', 'DC').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'DCA').property('city', 'Washington DC').property('state', 'DC').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'WAS').property('city', 'Washington DC').property('state', 'DC').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'ALO').property('city', 'Waterloo').property('state', 'IA').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'ART').property('city', 'Watertown').property('state', 'NY').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'ATY').property('city', 'Watertown').property('state', 'SD').property('country', 'USA').property('dst', 'ZZZ') :> g.addV('airport').property('iata', 'CWA').property('city', 'Wausau').property('state', 'WI').property('country', 'USA').property('dst', 'ZZZ') :>
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finium^®^ 1Mv1 microarray (98.7%). Both arrays genotype roughly 1,000,000 single nucleotide polymorphisms (SNPs) and the overlap between the SNP sets is almost perfect. The SSC sample \[[@B19]\] includes \>2,000 genotyped families. However, our analyses targeted a homogeneous subset of these data. First, we included only samples genotyped on an Illumina 1M array; families had to be 'quads' consisting of an unaffected mother and father, an affected proband and an unaffected sibling; and all members of a quad had to have complete genotypes (\>95% completion rate). Only samples of European ancestry were included. European ancestry for the SSC families was determined using GemTools \[[@B22],[@B23]\] for all available SSC probands. To conduct the ancestry analysis we selected 5,156 SNPs with at least 99.9% calls for genotypes, had minor allele frequency MAF \>0.05, and were at least 0.5 Mb apart. Individuals were clustered into nine ancestry groups based on four significant dimensions of ancestry. The central five clusters, which held a total of 1,686 families, were identified as being of European descent. The ancestry cluster information combined with complete genotype information yielded a total of 965 SSC families for the analysis. The AGP Stage 1 dataset \[[@B16],[@B20]\] comprised 1,471 families, of which 1,141 were previously identified to be of European ancestry \[[@B20]\]. European ancestry was confirmed by analyses identical to those applied to the SSC families (see Additional file [1](#S1){ref-type="supplementary-material"}: Figure S1). Clinical evaluation ------------------- Probands for the SSC and AGP cohorts were diagnosed in a similar manner (for diagnostic protocol for SSC, see \[[@B19]\]; for AGP, see \[[@B16],[@B20]\]). All SSC parents were screened for Autism Spectrum Disorder by the Broad Autism Phenotype Questionnaire \[[@B24]\] (self-report) and the Social Reciprocity Scale - Adult Research Version \[[@B25]\] (informant report). Moreover, family history evaluation excluded first-, second-, or third-degree relatives who met diagnostic criteria for ASD or intellectual disability. For AGP families 46.2% were known to be multiplex, another 38.2% were identified as simplex on the basis of a family history indicating no known first- to third-degree relatives with ASD, and the remaining 15.6% were of unknown status. Note that most AGP parents were not systematically evaluated for ASD, unlike those from the SSC, and when AGP parents were systematically evaluated, the results were not used to screen out affected individuals and thus multiplex families. In addition, while all available SSC family members were genotyped, only parent-proband trios were genotyped for the AGP even when additional siblings were available. Control subjects ---------------- Controls derived from a convenience sample, specifically 1,663 individuals from HealthABC \[[@B26]\]. Control samples were also genotyped on the Illumina Infinium^®^ 1Mv3 (duo) array, like most of the AGP data, providing excellent comparability with the case dataset. Moreover, we reasoned that ASD is sufficiently rare (approximately 1% \[[@B27]\]) that screened and unscreened controls would yield similar results. Filtering --------- To make heritability estimates comparable, we filtered all families and control subjects based on the following criteria: all were of European descent as determined by genetically-estimated ancestry (Additional file [1](#S1){ref-type="supplementary-material"}: Figure S1); genotypes for all family members met stringent quality control (QC) criteria; and control samples met identical QC criteria. For the three data sets we first chose SNPs genotyped on all platforms. Then ambiguous AT, TA, CG, and GC SNPs were removed. A total of 813,960 SNP across the 22 autosomes and chromosome X were included for further quality evaluation. At the level of individuals, we required that genotyping completion rate be greater than 98%, that there be no discrepancy regarding nominal and genotype-inferred sex, and no individuals in different families were closely related. At the level of individual SNPs, each SNP must have a genotype completion rate \> 98%, have MAF \> 0.01, and produce a *P*-value for Hardy-Weinberg equilibrium \> 0.005. Following these QC steps, data from 965 SSC quad families and 1,141 AGP families were analyzed using genotypes from 713,259 SNPs. Statistical calculations and motivation --------------------------------------- ### Estimating heritability as a case-control contrast Heritability of ASD from probands versus controls was estimated using GCTA software \[[@B28]\], which encodes the theory laid out in \[[@B17],[@B18]\]. Prevalence of ASD was taken to be 1% \[[@B27]\]. For each of the analyses, Genetic Relationship Matrices (GRM) were determined for each of the 23 chromosomes using the \--make-grm option in GCTA \[[@B28]\]. These were then combined in an overall matrix, using the \--mgrm option in GCTA. The first 10 principal components of ancestry were determined using \--pca in GCTA. These 10 PCA were then used as covariates for estimating the heritability using \--reml in GCTA. A prevalence of 0.01 for autism spectrum disorders was used to transform the heritability on the observed scale to the heritability on the liability scale. ### The logic of estimating heritability from unaffected family members Due to the screening of SSC samples, no SSC parents would meet criteria for ASD. Given that is the case, what is the justification for assigning them to be affected and contrasting them to controls to estimate the heritability in the parental generation? Under the additive heritability model parents transmit many genetic variants of small effect to their offspring, with the expectation that half would be transmitted from each parent. The parents of probands are thus more similar at liability loci than expected by chance, and our goal is to estimate this increased genetic similarity. Calling the parents affected and contrasting their genotypes to that of controls is a natural approach to estimating their genetic contribution to liability and it has precedence in quantitative genetics, such as estimation of the heritability of milk production from its covariance arising from bulls, when only the bull's female progeny give milk (for example \[[@B29]\]). A similar argument follows for unaffected siblings from SSC families. These siblings should receive a random sample of the parent's genomes and, in expectation, this sampling would include half the liability alleles carried by each parent. Thus the unaffected offspring should mirror the average liability carried by the parents and this level can be estimated by calling them affected and contrasting their genotypes to those from controls. ### Simulations to compute expected heritability for parents and pseudo-controls While the literature contains numerous references to the burden of risk variants carried by parents of simplex versus multiplex families, we could not find quantitative genetics analyses of it as a function of ascertainment (there is related work on the impact of multi-locus inheritance on the power of candidate gene association studies \[[@B30],[@B31]\]). We therefore evaluated the *expected* heritability for parents, unaffected siblings, and pseudo-controls on the basis of simulations and the theory of quantitative genetics regarding the selection differential (for ASD, approximately 1%) and the response to selection (expected change in the population's mean liability). The simulations are designed to mimic ascertainment for simplex and multiplex families. One thousand SNPs having an impact on liability were simulated. The allele frequency for SNP *i*, *p*~*i*~, varied between 0.01 and 0.99. Overall heritability *h*^*2*^ across all *n* = 1000 SNPs was set to be either 0.50 or 0.75 for probands with ASD. The relative importance of each SNP, *w*~*i*~, was determined by first selecting a fraction t~*i*~ between 0 and 1 at random using a uniform distribution. These 1000 values were added to obtain *T*, and each SNP was weighted by *w*~*i*~ = t~*i*~/T. The allele substitution effect for each SNP i was then determined as $a_{i} = \sqrt{\frac{w_{i}h_{i}^{2}}{2p_{i}\left( {1 - p_{i}} \right)}}$. For each simulation 1000 families were generated consisting of a father, mother, and one child (AGP simplex) or two children (SSC simplex or AGP multiplex). Genotypes for the parents were assigned at random using the allele frequencies, while children received alleles from the parents using the rules of Mendelian inheritance. Likewise a pseudo-control was generated by comparing the genotype of the parents to that of the proband and assigning the un-transmitted allele of each parent as the alleles for the pseudo-control's genotype. After all genotypes in a family were assigned, the genetic contribution to the underlying liability phenotype for each individual j in the family was determined by *G*~*j*~ = ∑ ~*i* = 1~^*n*^*x*~*i*~*a*~*i*~ − *μ*~*G*~ in which *x*~*i*~ is the allele count for SNP i and *μ*~*G*~ = ∑ ~*i* = 1~^*n*^*p*~*i*~(1 − *p*~*i*~)*a*~*i*~ is the average genetic contribution over all genotypes. To simulate the environmental influence on the phenotype of individual j, e~j~, we drew a random number from a normal distribution with mean 0 and variance (1-*h*^*2*^). The liability phenotype was then determined as *y
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much better than that. I'm grateful for your willingness to work around the difficulties that stem from my military service, especially that one time I had to—REDACTED FOR REASONS OF NATIONAL SECURITY—man, that was wild. To my parents and sisters: Thanks for all the endless support and encouragement and feedback. You guys have always rocked, and you always shall. To my favorite alpha-reader (who also happens to be my wife): Sorry about all the nights you spent staring at the back of my head while I typed and/or stared at the blank screen in defeat. I know you'd have rather snuggled up on the couch and watched TV, or anything else really, but I couldn't have done any of this without you. To my boys: Thank you for constantly reminding me about the need for imagination. And to my readers: What is a story without someone to share it with? You make all of this worthwhile. Seriously. ABOUT THE AUTHOR Born in 1983, NATHAN GARRISON has been writing stories since his dad bought their first family computer. He grew up on tales of the fantastic. From Narnia and Middle-­Earth to a galaxy far, far away, he has always harbored a love for things only imagination can conjure up. He counts it among the greatest joys of his life to be able to share the stories within him. He has two great boys and an awesome wife who is way more supportive of his writing efforts than he thinks he deserves. Besides writing, he loves playing guitar (the louder the better), cooking (the more bacon-­y the better), playing board/video/card games with friends and family, and reveling in unadulterated geekery. www.nathangarrison.com : @NR_Garrison Discover great authors, exclusive offers, and more at hc.com. ALSO BY NATHAN GARRISON Veiled Empire COPYRIGHT This is a work of fiction. Names, characters, places, and incidents are products of the author's imagination or are used fictitiously and are not to be construed as real. Any resemblance to actual events, locales, organizations, or persons, living or dead, is entirely coincidental. SHADOW OF THE VOID. Copyright © 2016 by Nathan Garrison. All rights reserved under International and Pan-­American Copyright Conventions. By payment of the required fees, you have been granted the nonexclusive, nontransferable right to access and read the text of this e-­book on screen. No part of this text may be reproduced, transmitted, downloaded, decompiled, reverse-­engineered, or stored in or introduced into any information storage and retrieval system, in any form or by any means, whether electronic or mechanical, now known or hereafter invented, without the express written permission of Harper­Collins e-­books. For information, address Harper­Collins Publishers, 195 Broadway, New York, NY 10007. EPub Edition MAY 2016 ISBN: 9780062451996 Print Edition ISBN: 9780062452924 10 9 8 7 6 5 4 3 2 1 ABOUT THE PUBLISHER Australia HarperCollins Publishers Australia Pty. Ltd. Level 13, 201 Elizabeth Street Sydney, NSW 2000, Australia www.harpercollins.com.au Canada HarperCollins Canada 2 Bloor Street East - 20th Floor Toronto, ON, M4W, 1A8, Canada www.harpercollins.ca New Zealand HarperCollins Publishers New Zealand Unit D1, 63 Apollo Drive Rosedale 0632 Auckland, New Zealand www.harpercollins.co.nz United Kingdom HarperCollins Publishers Ltd. 1 London Bridge Street London SE1 9GF, UK www.harpercollins.co.uk United States HarperCollins Publishers Inc. 195 Broadway New York, NY 10007 www.harpercollins.com 1. High Regnosist Lekrigar was rumored to have escaped the destruction at both the palace and the fields outside Mecrithos. Though not confirmed, he was never seen or heard from within the empire again. 2. See: Chapter 8: The False Revolution, Section 2a: Key Figures 3. See: Chapter 11: The Rise of Chaos, Section 4: The Great Blindness and the Non-­Battle for Humanity 4. See: Chapter 13: The Fall of Chaos 1. Dedication 2. Contents 3. A Page from History of the Veiled Empire 4. Prologue 5. Part I 6. Chapter 1 7. Chapter 2 8. Chapter 3 9. Chapter 4 10. Chapter 5 11. Chapter 6 12. Part II 13. Chapter 7 14. Chapter 8 15. Chapter 9 16. Chapter 10 17. Chapter 11 18. Chapter 12 19. Part III 20. Chapter 13 21. Chapter 14 22. Chapter 15 23. Chapter 16 24. Chapter 17 25. Chapter 18 26. Chapter 19 27. Part IV 28. Chapter 20 29. Chapter 21 30. Chapter 22 31. Chapter 23 32. Epilogue 33. Acknowledgments 34. About the Author 35. By Nathan Garrison 36. Copyright 37. About the Publisher St. Finbarr's Cemetery St. Finbarr's Cemetery () in Cork, Ireland, is the city's largest and one of the oldest cemeteries in Ireland which is still in use. Located on the Glasheen Road, it was first opened in the 1860s. The entrance gateway was erected circa 1865, and the mortuary chapel consecrated in 1867. Many of the early burials were of the wealthy citizens of the city. Unlike older cemeteries, St. Finbarr's was professionally laid out with numbered pathways and wide avenues. Burials Among those buried at St. Finbarr's Cemetery are hurler and Taoiseach Jack Lynch; the sculptor Seamus Murphy, the antiquarian Richard Rolt Brash who was among the first to decipher writing in the ancient Ogham writing style; and Cork's first Lord Mayor Daniel Hegarty. St. Finbarr's contains one of the largest burial plots of Irish Republicans who died during the 1920s. There are also more recent burials of members of the Provisional IRA and the Official IRA. This is known as the Cork Republican Plot, and among those buried there are former Lords Mayor of Cork Terence McSwiney and Tomás Mac Curtain, hunger striker Joseph Murphy. In the early hours of 17th March 1963, in protest at the unveiling later that day of a monument in the Republican Plot by President De Valera, IRA volunteers Desmond Swanton and Jeremiah Madden attempted to blow up the monument. However, during this attempt there was an explosion which killed Swanton and severely injured Madden (who lost an eye and a leg). Other republicans who are buried at St. Finbarr's, but not in the Republican Plot, include Flying Column leader Tom Barry, former government minister James J. Walsh and Dan "Sandow" O'Donovan. Commemorations of the 1916 Rising are held annually at the Republican Plot on Easter Sunday by various groups including Sinn Féin, Fianna Fáil, the Workers' Party of Ireland and Republican Sinn Féin. The "musicians' corner" contains the graves of Aloys Fleischmann (Senior) and Aloys Fleischmann, and the composer Arnold Bax. It also contains a mass grave where 72 women who died at St. Vincent's, Peacock Lane, a Magdalene Laundry, are buried. References External links National Inventory of Architectural Heritage: St. Finbarr's Cemetery Category:Roman Catholic cemeteries in the Republic of Ireland Category:Religion in County Cork Category:Roman Catholic Diocese of Cork and Ross--- abstract: 'Communication complexity is an area of classical computer science which studies how much communication is necessary to solve various distributed computational problems. Quantum information processing can be used to reduce the amount of communication required to carry out some distributed problems. We speak of pseudo-telepathy when it is able to completely eliminate the need for communication. The matching game is the newest member of the family of pseudo-telepathy games. After introducing a general model for pseudo-telepathy games, we focus on the question what the smallest size of inputs is for which the matching game is a pseudo-telepathy game.' --- [IVAN FIALÍK]{} Introduction ============ Quantum information processing allows us to solve problems that we are not able to solve in the classical world at all or at least that we are not able to solve efficiently. This is true also in the field of communication complexity. The first convincing evidence that quantum communication protocols can be more efficient than classical ones was given in 1998 by Buhrman, Cleve and Wigderson [@qvccac]. They found a problem whose quantum communication complexity is
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room.exits) elif com[0] == "name": self.hero.name_self() elif com[0] == "info": self.info() elif com[0] == "heal": self.hero.heal_self() elif com[0] == "?": self.list_commands() else: print ("lol wut") def combat(self, attacker, defender): while defender.hp > 0 and attacker.hp > 0: attack = int(random.random() * attacker.attack) defense = int(random.random() *defender.defense) print "Attack: %s vs Defense: %s" % (str(attack), str(defense)) if attack > defense: print "You hit the %s for %s HP." % (defender.name.capitalize(), str(attack)) defender.hp -= attack elif attack == defense: print "The attack missed. You feel kind of disappointed." else: print ("The %s hit you for %s HP and it hurt real bad.") % (defender.name.capitalize(), str(attack)) self.hero.hp -= attack if self.hero.hp < 2: print "You attempt to escape..." time.sleep(1) break time.sleep(.5) if defender.hp < 1: print "You killed the %s. How sad for the %s's family." % (defender.name.capitalize(), defender.name.capitalize()) self.hero.xp_up(defender.xp) del self.current_room.monster_list[defender.name] if self.hero.hp < 1: self.hero.death() def level_up(self): if self.hero.xp > self.hero.level**2 * 10: self.hero.level += 1 print "You've reached level " + str(self.hero.level) self.hero.max_hp += self.hero.level self.hero.hp = self.hero.max_hp def populate(self): for i in range(self.hero.level): new_monster = random.choice(["ogre", "orc", "goblin"]) self.current_room.monster_list[new_monster] = Monster(new_monster) def look(self): print self.current_room.description print "You can exit to: %s" % ', '.join(self.current_room.exits) monster_list= [] for name in self.current_room.monster_list: monster_list.append(self.current_room.monster_list[name].name.capitalize()) if monster_list: print "You see: %s" % ', '.join(monster_list) def look_monster(self, monster): print ("The %s has %s HP, %s attack, %s defense, and is worth %s XP." % (monster.name.capitalize(), monster.hp, monster.attack, monster.defense, monster.xp)) def move(self, exit): if exit in self.current_room.exits: self.current_room = Room(exit) self.populate() self.look() elif exit == self.current_room.name: print ("You're already here.") else: print ("You can't get there from here.") def update(self): self.level_up() if self.hero.hp <= 0: self.hero.death() time.sleep(2) game = Game() def prompt(self): return '\n' + self.hero.name + " HP:" + str(int(self.hero.hp)) + " XP:" + str(self.hero.xp) + " >" def output(self): pass game = Game() game.populate() print ("Welcome, adventurer.") game.list_commands() game.hero.name_self() game.hero.look_self() game.look() while True: game.handle_input() game.update() game.output() A: A few suggestions: Simplify and reduce duplication using inheritance, for example: class Character(object): # note new-style classes def __init__(self, name, hp, attack, defence, xp): self.name = name self.hp = hp self.attack = attack self.defence = defence self.xp = xp class Monster(Character): def __init__(self, name): super(Monster, self).__init__(name, random.randint(2,10), random.randint(2,5), random.randint(2,5), random.randint(2,8)) class Hero(Character): MAX_HP = 3 def __init__(self, level=1): super(Hero, self).__init__('', self.MAX_HP, level+5, level+5, 0) self.level = level Move general class data out of the instance: class Room(object): ROOM_DATA = {"home": {"description": "You're at home. This is where you live, unfortunately.", "exits": ["forest"]}, "forest": {"description": "You're in a dark forest. It's fairly gloomy.", "exits": ["home", "lake"]}, "lake": {"description": "You see a lake circled by rocks. It's too cold to swim.", "exits": ["forest", "mountain"]}, "mountain": {"description":"You can see for miles around. Don't fall off.", "exits": ["lake"]}} def __init__(self, key): self.description = self.ROOM_DATA[key]["description"] self.exits = self.ROOM_DATA[key]["exits"] self.name = str(key) self.monster_list = {} Similarly e.g. Game.COMMAND_LIST isn't instance-specific. Simplify the display using "magic methods" and str.format: class Monster(Character): ... def __str__(self): template = "The {0} has {1.hp} HP, {1.attack} attack, ..." # etc. return template.format(self.name.capitalize(), self) class Game(object): ... def look_monster(self, monster): print str(monster) Use looping rather than recursion for input validation (see e.g. this SO community wiki): def name_self(self): while True: self.name = raw_input("What do you call yourself, anyway? ") if self.name != "": break Consider structuring your functions differently, such that they call each other, to cut down multiple lines of calls at the top level. For example: Game.__init__ could call populate and look; Hero.__init__ could call name_self and look_self(); and you could add Game.play_round to call handle_input(), game.update() and game.output(). Put the top-level code in an if __name__ == '__main__': block (see e.g. this SO question). A: The other answer from @jonrsharpe addresses the most important points, but a few other nits are: Eliminate the "info" choice in handle_input If the user types in "info" at the command line, the reward is an error message and the end of the program. Fix the calculating and reporting in heal_self The message starting with "You healed your self for %d HP..." is a bit misleading since that reports the previously calculated amount which is calculated as self.xp * .2 rather than the actual number which is self.xp *= .5 and is capped by self.hp_limit() Consider replacing "magic numbers" with named parameters At some point, you might wish to change, say, how "tough" monsters can be, so rather than having self.attack = random.randint(2,5) you may want to put the 2 and 5 into variables that may be tuned or even altered during the game. For example, maybe mountain Ogres are tougher than forest Ogres, or perhaps monsters get tougher as the player does. Start fractional numbers with
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kom, 93, Dutch film actress. George "Wild Child" Butler, 68, American blues musician. Sergio Campanato, 75, Italian mathematician. Reverend Walter Halloran, 83, American priest who participated in the exorcism on which The Exorcist was based. Brian Luckhurst, 66, English cricketer, cancer. Peter Malkin, 77, Israeli Mossad agent, the man who captured Adolf Eichmann. Stephen Anthony Mobley, 39, American convicted murderer, executed by lethal injection. Barry Stigler, 57, American voice actor. 2 H. E. N. Bredin, 88, British army general. Martin Denny, 93, American founder of exotica musical genre, bandleader. Hermann Dörnemann, 111, German supercentenarian and World War I veteran, oldest living person in Germany, heart failure. Tillie K. Fowler, 62, U.S. politician, former four-term Florida congresswoman. Rick Mahler, 51, American baseball pitcher, heart attack. 3 George Atkinson, 69, American businessman, inventor of the video rental. James Corbett, 96, Australian politician. Max M. Fisher, 96, American millionaire philanthropist, listed in Forbes 400. Rinus Michels, 77, Dutch football player and coach, former Dutch national football team coach. Raveendran, 61, Indian composer and playback singer. Guylaine St. Onge, 39, Canadian actress, cancer. 4 Mihai Brediceanu, 84, Romanian musician. Nicola Calipari, 51, Italian intelligence officer, shot by the US Army in Iraq. Douglas Dumbleton, 86, New Zealand cricket umpire. Una Hale, 82, Australian operatic soprano. Yuri Kravchenko, 53, Ukrainian General of Internal Service and statesman, former interior minister of Ukraine. Carlos Sherman, 70, Uruguayan-born Belarusian translator and writer. 5 George Worsley Adamson, 92, American-born British illustrator. Harold Brooks-Baker, 71, American publishing director of Burke's Peerage Limited. Sergiu Comissiona, 76, Romanian orchestra conductor. James McGirr Kelly, 76, American federal judge. David Sheppard, Baron Sheppard of Liverpool, 75, English former international cricketer and Church of England bishop, cancer. 6 Larned B. Asprey, 85, American chemist. Hans Bethe, 98, German-born American Nobel Laureate in Physics, discover of stellar fusion. Danny Gardella, 85, American baseball player, New York Giants outfielder who challenged baseball's reserve clause in a 1947 federal lawsuit Gladys Marín, 63, Chilean communist politician, cancer. Chuck Thompson, 83, American Baltimore Orioles broadcaster, complications of massive stroke. Tommy Vance, 64, British radio DJ and TV host, stroke. Teresa Wright, 86, American actress, heart attack. 7 Edwin Adams Cotto, 26, Puerto Rican drug dealer, accused in the Laura Hernandez drug case; killed during a riot in a Dominican Republic jail. Walter Arendt, 80, German politician. A. W. Baxter, 78, Canadian winemaker. Helon Blount, 76, American musical theatre actress, born in Texas. John Box, 85, British film production designer, worked closely with David Lean. Terry Buck, 61, Australian swimmer. Debra Hill, 54, American screenwriter and film producer, co-writer of Halloween. Philip Lamantia, 77, American surrealist poet. Sir Peregrine Rhodes, 79, British diplomat, Ambassador to Greece (1982–1985) James Stuart, 76, American opera director. 8 Ross Benson, 56, British journalist for the Daily Mail and award-winning foreign correspondent. Larry Bunker, 76, American jazz drummer. Anna Haycraft, 72, British writer (also known as Alice Thomas Ellis), lung cancer. César Lattes, 80, Brazilian physicist, contributed to the physics of elementary particles and discovered the pion. Aslan Maskhadov, 53, Chechen separatist leader, killed by Russian troops. Brigitte Mira, 94, German theatrical actress. Fred Rice, 86, American football coach. Jeremy Russell, 60, American cofounding member of the band Blue Cheer. 9 Thomas F. August, 78, American lawyer and politician. Meredith Davies, 82, British conductor. Glenn Davis, 80, American football player, Heisman Trophy winner, prostate cancer. Josef Fuchs, 93, German Roman Catholic theologian. Sheila Gish, 62, English stage actress, cancer. Kathie Kay, 86, Scottish big band singer. Chris LeDoux, 56, American country music and rodeo star, complications from liver cancer. William Murray, 78, American mystery novelist. István Nyers, 80, Hungarian footballer. Jeanette Schmid, 80, German-born professional transsexual whistler. Redmond A. Simonsen, 62, American game designer. 10 Dave Allen, 68, Irish comedian. Charles R. Baxter, 75, American physician, pneumonia, surgeon who tried to save JFK. Sir James Beament, 83, British biologist. Danny Joe Brown, 53, American lead singer of Molly Hatchet. Bruno Manser, 45, Swiss environmental activist. Sy Wexler, 88, American maker of educational films. 11 Rowland Barnes, 64, American jurist, murdered in court. Karen Wynn Fonstad, 59, American cartographer and academic, author of atlases of fictional worlds, breast cancer. Len Morgan, 82, American aviator and writer. Humphrey Spender, 94, British photojournalist, notably for Picture Post. 12 Tony Arena, 86, American football player. Aleksandar Atanacković, 84, Serbian footballer. Carl Beck-Friis, 83, Swedish Olympic shooter Joseph M. Breitenbeck, 90, American Roman Catholic prelate, Bishop of Grand Rapids (1969–1989). Norbert Callens, 80, Belgian cyclist. Bill Cameron, 62, Canadian journalist, cancer. Lisa Fittko, 95, German World War II dissident who led Jews over the Pyrenees to freedom. Stanley Grenz, 55, American Christian theologian. Amanullah Khan, 71, Pakistani Test cricket umpire. Stavros Kouyioumtzis, 73, Greek music composer Edward E. Simbalist, 61, American role-playing game designer 13 Old Man Bukashkin, 66, Russian poet and artist. Lyn Collins, 56, American soul singer, aka "Female Preacher" Jason Evers, 83, American actor, star of B-movie Brain That Wouldn't Die Ahmed Hassan Diria, 67, Tanzanian politician and diplomat, foreign minister from 1990 to 1993. Frank House, 75, American baseball player, retired Major League Baseball catcher and Alabama legislator 14 Stan Campbell, 74, American NFL player. Richard Cooper, 58, Australian jurist. Richard S. Forrest, 72, American novelist and short story writer, smoking and lung disease. Janet Reger, 69, British designer of women's lingerie. Sir Donald Thompson, 73, British politician. Simon Webb, 55, British chess grandmaster living in Sweden, stabbed to death by his son. Akira Yoshizawa, 94, Japanese origami master. 15 Bob Bellear, 60, Australian jurist, first indigenous judge in Australia. Audrey Callaghan, 89, Spouse of the Prime Minister (1976–1979). Don Durant, 82, American singer/actor, star of Johnny Ringo series. Loe de Jong, 90, Dutch historian. Otar Korkiya, 81, Georgian basketball player. Bill McGarry, 77, English football manager. Judith Scott, 61, American outsider artist. Shoji Nishio, 77, Japanese aikido teacher holding the rank of 8th dan shihan from the Aikikai. 16 Wanda Alston, 45, American activist. Arciso Artesiani, 83, Italian motorcycle racer. Todd Bell, 47, American football safety, former Chicago Bears player. Mohammed Bijeh, 30, Iranian serial killer. Ralph Erskine, 91, British architect (Byker Wall). Anthony George, 84, American actor. Allan Hendrickse, 77, South African politician. Justin Hinds, 62, Jamaican vocalist and songwriter. William Lehman, 91, American politician, represented Dade County, Florida in U.S. Congress. Dick Radatz, 67, American baseball player. 17 Renzo Alverà, 72, Italian bobsledder. William J. Bakrow, 81, American academic administrator. Irvine Barrow, 92, Canadian
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not \in \mathcal{P}$. By Proposition \[prop\_smoothprop\](c), there exists an induced subhypergraph $G$ of $\tilde{H_i}$ such that $G \in \mathcal{F}(\mathcal{P})$ and, thus, $\delta(G) \geq d(\mathcal{P})=r$. Since $H_i$ is in $\mathcal{P}$ but $G$ is not, $G$ contains a vertex of $H_i'$. Thus, the hypergraph $G'=H_i'[V(G) \cap V(H_i')]$ is non-empty. However, since $H_i'$ is strictly $f_i$-degenerate, there is a vertex $v$ in $G'$ such that $d_{G'}(v) < f_i(v) = r - d_{H_i + v} (v)$ and thus $d_G(v) \leq d_{G'}(v) + d_{H_i+v}(v) < r$, a contradiction. Hence, $B$ is not $f$-partitionable. Since $d_H(v)=r|L(v)|$ for all $v \in V(B)$, we obtain that $$\begin{aligned} \sum_{i=1}^p f_i(v) & = \sum_{i \in L(v)}f_i(v) \geq \sum_{i \in L(v)}(r-d_{H_i+v}(v))\\ & = d_H(v) - \sum_{i \in L(v)} d_{H_i+v}(v) \geq d_B(v)\end{aligned}$$ for all $v \in V(B)$. Thus, by Theorem \[Theorem:Hauptsatz\] and as $B$ is a block, $(B,f)$ is of type (M), (K) or (C). If $(B,f)$ is not of type (M), then $B$ is a brick and we are done. Thus assume that $(B,f)$ is of type (M). Then, there is exactly one index $i$ such that $f_i(v) = d_B(v)$ for all $v \in V(B)$ and $f_j(v) = 0$ for $j \neq i$ from the set $\{1,2,\ldots,p\}$. As a consequence, $d_{H_j+v}(v) \geq r$ for all $j \in L(v) \setminus\{i\}$ and thus, $d_B(v) \leq r$ for all $v \in V(B)$. If $B \in \mathcal{P}$, we have $\Delta(B) \leq r$ and there is nothing left to show. If $B \not \in \mathcal{P}$, then by Proposition \[prop\_smoothprop\](c), $B$ contains an induced subhypergraph $B'$ from $\mathcal{F}(\mathcal{P})$. Since $d_B(v) \leq r$ for all $v \in V(B)$ and since $\delta(B') \geq d(\mathcal{P})= r$, it must hold $B=B'$ and $d_B(v) = r$ for all $v \in V(B)$. Consequently, $B \in \mathcal{F}(\mathcal{P})$ and $B$ is $r$-regular. This completes the proof. A Gallai-type bound for the degree sum of critical linear hypergraphs ===================================================================== The topic of finding lower bounds for the number of edges, respectively the degree sum of critical graphs and hypergraphs with respect to some coloring concept has already been examined extensively in the past. Regarding proper colorings of simple graphs (not hypergraphs), Gallai [@Gal63b] proved that for a $(k+1)$-critical graph $G\neq K_{k+1}$, that is, a graph which has chromatic number $k+1$ but each proper subgraph has chromatic number at most $k$, it holds $$d(G) \geq k |V(G)| + \frac{k- 2}{k^2 + 2k -2}|V(G)|$$ if $k\geq 3$. For simple hypergraphs, an even stronger bound was proven by Kostochka and Stiebitz [@KosStieb03]. Mihók and Škrekovski [@MiSkre01] proved a Gallai-type bound for the case of $(\mathcal{P},L)$-critical graphs. In the next section, with the help of Stiebitz and Kostochka’s approach, we show that the bound also holds for $(\mathcal{P},L)$-critical locally linear hypergraphs. Let $\mathcal{P}$ be a smooth additive hypergraph property and let $H$ be a $(\mathcal{P},L)$-critical hypergraph, whereas $L$ is a list-assignment for $H$ with $|L(v)|=k$ for all $v \in V(H)$. Then we say that $H$ is **locally linear with respect to** $(\mathcal{P},L)$ if $H(V(H,\mathcal{P},L))$ is simple. Furthermore, if $H$ is a $(\chi^\ell,\mathcal{P})$-critical hypergraph with $\chi^\ell(H:\mathcal{P})=k+1$, we say that $H$ is **locally linear with respect to** $(\chi^\ell,\mathcal{P})$ if $H$ is locally linear with respect to $(\mathcal{P},L)$ for some list-assignment $L$ with $|L(v)|=k$ for all $v \in V(H)$ such that $H$ is $(\mathcal{P},L)$-critical. Note that if $H$ is locally linear with respect to $(\mathcal{P},L)$, then $H$ is locally linear for each list-assignment $L'$ satisfying that $H$ is $(\mathcal{P},L')$-critical and that $|L'(v)|=|L(v)|$ for all $v \in V(H)$, since for the low vertex hypergraphs it clearly holds $V(H,\mathcal{P},L)=V(H,\mathcal{P},L')$. Note that if $H$ is a simple hypergraph, then the shrinking operation may still lead to parallel edges. Since it will be necessary that the low vertex hypergraph is simple, we need to limit ourselves to locally linear hypergraphs. Moreover, it is important to note that if $\mathcal{P}=\mathcal{O}$, then any $(\mathcal{P},L)$-critical hypergraph is locally linear with respect to $(\mathcal{P},L)$ (see [@KosStieb03]). In the following, let $\mathcal{P}$ be a smooth additive hypergraph property with $d(\mathcal{P})=r \geq 1$, let $k \geq 1$ and let $\delta=kr$. Furthermore, let $H$ be a locally linear hypergraph with respect to $(\chi^\ell,\mathcal{P})$ where $\chi^\ell=k+1$ for some $k \geq 1$. Let $n=|H|$ and let $$a(\delta,n)=\delta n + \frac{\delta-2}{\delta^2 + 2 \delta - 2}n.$$ Our aim is to prove that $d(H) \geq a(\delta,n)$. Note that the $(\chi^\ell, \mathcal{P})$-critical locally linear hypergraphs for $\chi^\ell(H:\mathcal{P})=2$ (i.e. $k=1$) are exactly the hypergraphs from $\mathcal{F}(\mathcal{P})$ (by Proposition \[prop\_smoothprop\](b) and since $H$ being $(\chi^\ell, \mathcal{P})$-critical implies that $H$ is ($\mathcal{P},L)$-critical with $L(v)=\{1\}$ for all $v \in V(H)$). In this case, however, the boundary is not true for many properties. As an example consider the class $D_{r-1}$ of strictly $r$-degenerate hypergraphs. Then it is easy to check that $\mathcal{F}(\mathcal{P})$ contains all $r$-regular connected hypergraphs, and thus, the bound clearly does not hold for $r \geq 3$. Thus, in the following we will assume $k \geq 2$ and, therefore, $\delta \geq 2$. If $\delta=2$, this implies $r=1$ and $k=2$. Then, $\chi^\ell(H:\mathcal{P})=3$ and, in particular, there is a list assignment $L$ for $H$ with $|L(v)|=2$ for all $v \in V(H)$ such that $H-v$ is $(\mathcal{P},L)$-colorable for all $v \in V(H)$, but $H$ is not. Consequently, $H$ is $(\mathcal{P},L)$-critical, and, by Proposition \[prop\_pl-vertex-crit\](a), it holds $d_H(v) \geq r|L(v)|=2$ for all $v \in V(H)$. Thus, as $\delta = 2$, it trivially holds $d(H)\geq 2n = a(2,n)$. Hence, as of now we
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with him?" "Do you mean Leo?" "Yes." "I hope you don't presume to dictate the friends with whom I may . . ." "Kira!" He was startled by the icy firmness of her voice; he was apologizing: "Kira, I'm sorry. Of course I didn't mean . . . Forgive me. I know I have no right to say . . . But you see, I've always disliked him." She smiled gaily, as if nothing had happened, and leaning into the shadow of the window niche, pressed his fingers swiftly. "Don't worry," she whispered and, moving away from him, turned, shaking her hair, throwing at him through the tousled locks a glance of such warm, sparkling understanding that he caught his breath, thrilled by the secret they were guarding together, among strangers, for the first time. Vasili Ivanovitch sat alone in a corner, under a lamp, and the light of a rose satin shade made his white hair pink. He looked at the shuffling feet, at the military boots of young Communists, at the blue fog of smoke streaks that billowed halfway up to the ceiling, in soft, round waves, like a heavy, transparent mixture boiling slowly, at a gold cross on a black velvet ribbon around Lydia's throat, a bright spark piercing the fog across the room. Kira approached and sat down beside him. He patted her hand, and said nothing, and knew that she knew. Then he said, as if she had followed his unspoken thoughts: ". . . I wouldn't mind so much if he loved her. But he doesn't. . . . Kira, you know, when he was a little boy with such big black eyes, I used to look at my customers, those ladies that were like paintings of empresses, and I wondered which one of them was the mother of the little beauty, growing up somewhere, who, some day, would be my daughter, too. . . . Have you met Marisha's parents, Kira?" Galina Petrovna had cornered Leo; she was saying enthusiastically: ". . . so glad you're successful, Leo. I've always said that a brilliant young man, like you, would have no trouble at all. That dress of Kira's is magnificent. I'm so happy to see what good care you take of my little girl. . . ." Victor sat on the arm of a chair occupied by red-headed Rita Eksler. He leaned close to her, holding his cigarette to light the one at her lips. Rita had just divorced her third husband; she narrowed her eyes under the long red bangs and whispered confidential advice. They were laughing softly. Marisha approached timidly and took Victor's hand with a clumsy movement of coquetry. He jerked his hand away; he said impatiently: "We can't neglect our guests, Marisha. Look, Comrade Sonia is alone. Go and talk to her." Marisha obeyed humbly. Rita's glance followed her through a jet of smoke; Rita pulled her short skirt up and crossed her long, thin legs. "Indeed," said Comrade Sonia coldly with an accent of final authority, "I cannot say that I congratulate you upon your choice, Comrade Lavrova. A true proletarian does not marry out of her class." "But, Comrade Sonia," Marisha protested, stupefied, "Victor is a Party member." "I've always said that the rules of Party admission were not sufficiently strict," said Comrade Sonia. Marisha wandered dejectedly through the crowd of guests. No one looked at her and she had nothing to say. She saw Vasili Ivanovitch alone by the buffet, lining up bottles and glasses. She approached him and smiled hesitantly. He looked at her, astonished. She said with determination, very quickly, bluntly, running her words together, blushing: "I know you don't like me, Vasili Ivanovitch. But, you see, I . . . I love him so much." Vasili Ivanovitch looked at her, then said: "It's very nice, child," his voice expressionless. Marisha's family sat in a dark corner, solemn, morose, uncomfortable. Her father--a stooped, gray-haired man in a worker's blouse and patched trousers--clasped long, calloused hands over his knee; his face, with a bitter slash of a mouth, leaned forward, his fierce, brilliant eyes studying the room fixedly; his eyes were dark and young on a withered face. His wife huddled timidly behind him, pallid and shapeless in a flowered calico dress, her face like a sandy shore washed by many rains into a dull, quiet gray. Marisha's young brother, a lanky boy of eight, stood holding onto his mother's skirt, throwing angry, suspicious glances at little Acia. Victor joined Pavel Syerov and a group of three men in leather jackets. He threw one arm around Syerov's shoulders and the other around those of the secretary of their Party Cell; he leaned on them both, intimately, confidentially, his dark eyes smiling. Comrade Sonia, approaching, heard him whisper: ". . . yes, I'm proud of my wife's family and their revolutionary record. Her father--you know--he was exiled to Siberia, under the Czar." Comrade Sonia remarked: "Comrade Dunaev is a very smart man." Neither Victor nor Syerov liked the tone of her voice. Syerov protested: "Victor's one of our best workers, Sonia." "I said Comrade Dunaev is very smart," she repeated, and added: "I wouldn't doubt his class loyalty. I'm sure he had nothing in common with patrician gentlemen such as that Citizen Kovalensky over there." Pavel Syerov looked fixedly at Leo's tall figure bending over Rita Eksler. He asked: "Say, Victor, that man's name--it's Lev Kovalensky, isn't it?" "Leo Kovalensky, yes. He's a very dear friend of my cousin's. Why?" "Oh, nothing. Nothing at all." Leo noticed Kira and Andrei sitting side by side on a window sill. He bowed to Rita, who shrugged impatiently, and walked toward them slowly. "Am I intruding?" he asked. "Not at all," said Kira. He sat down beside her. He took out his gold cigarette case and, opening it, held it out to her. She shook her head. He held it over to Andrei. Andrei took a cigarette. Leo bent forward to light it, leaning over Kira. "Sociology being the favorite science of your Party," said Leo, "don't you find this wedding an occasion of particular interest, Comrade Taganov?" "Why, Citizen Kovalensky?" "As an opportunity to observe the essential immutability of human nature. A marriage for reasons of state is one of the oldest customs of mankind. It had always been advisable to marry into the ruling class." "You must remember," said Andrei, "the social class to which the person concerned belongs." "Oh, nonsense!" said Kira. "They're in love with each other." "Love," said Leo, "is not part of the philosophy of Comrade Taganov's Party. Is it?" "It is a question that has no reason to interest you," Andrei answered. "Hasn't it?" Leo asked slowly, looking at him. "That's what I'm trying to find out." "Is it a question that contradicts your . . . theory on the subject?" Andrei asked. "No. I think it supports my theory. You see, my theory is that members of your Party have a tendency to place their sexual desires high above their own class." He was looking straight at Andrei, but he pointed lightly, with his cigarette, at Marisha across the room. "If they do," Andrei answered slowly, "they're not always unsuccessful." He was looking straight at Kira, but he pointed at Victor. "Marisha looks happy," said Kira. "Why do you resent it, Leo?" "I resent the arrogant presumption of friends--" Leo began. "--who do not know the limit of a friendship's rights," Andrei finished. "Andrei," said Kira, "we're not being gallant to . . . Marisha." "I'm sorry," he said hastily. "I'm sure Citizen Kovalensky won't misunderstand me." "I don't," said Leo. Irina had lined glasses on trays and Vasili Ivanovitch had filled them. She passed them to the guests, smiling vaguely at the hands that took the glasses; her smile was resigned, indifferent; she was silent, which was unusual for her. The trays were emptied swiftly; the guests held the glasses eagerly, impatiently. Victor rose and the clatter of voices stopped short in a solemn silence. "My dear friends," Victor's voice was clear, vibrant with his warmest persuasiveness, "I have no words to describe my deep gratitude to
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agreements. See the NOTICE file # distributed with this work for additional information # regarding copyright ownership. The SFC licenses this file # to you under the Apache License, Version 2.0 (the # "License"); you may not use this file except in compliance # with the License. You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, # software distributed under the License is distributed on an # "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY # KIND, either express or implied. See the License for the # specific language governing permissions and limitations # under the License. class MouseButton(object): LEFT = 0 MIDDLE = 1 RIGHT = 2 Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses. Our objective was to determine the predictive value of specimen radiography for large core (14-gauge) needle biopsy of noncalcified breast masses. Eighty-four biopsies of 83 breast masses yielded 403 specimens. Specimens showing dense material on specimen radiography were predicted to be diagnostic; specimens showing intermediate- or low-density material were predicted to be nondiagnostic. Specimen radiographic and histopathologic findings were correlated for each specimen using vital dyes to mark individual specimens. Of the 403 specimens, 307 (76%) contained diagnostic material representative of the lesion, with a specific diagnosis achieved for 82 (99%) of 83 lesions (62 benign, 20 malignant). Of the 293 passes containing dense material, 268 (91%) proved to be diagnostic; 11 (18%) of 62 specimens containing only low-density material proved to be diagnostic. Of the 25 (9%) of 293 specimens containing radiographically dense but nondiagnostic material, 18 (72%) showed focal fibrosis and had missed the lesion; 15 (83%) of 18 such specimens were obtained in dense parenchyma. The positive predictive value of specimen radiography was 13 (100%) of 13 in fatty breasts; 77 (96%) of 80 in breasts with minimal scattered fibroglandular elements; 91 (94%) of 97 in heterogeneously dense breasts; and 35 (70%) of 50 in breasts with extremely dense parenchyma. Of the 16 lesions sampled stereotactically, specimen radiography helped assess the inadequacy of initial sampling in three (19%). In six (9%) of 68 sonographically guided biopsies, only one or two specimens could be obtained; specimen radiography helped us predict whether material was adequate for diagnosis. Radiography of core specimens obtained from noncalcified breast masses accurately reveals the adequacy of sampling unless the breast parenchyma is extremely dense. Such immediate assessment can help ensure adequate material from lesions that are difficult to biopsy and can thereby improve the diagnostic yield of large core needle breast biopsy.You are here Talisay Police to Probe Teener’s Death Talisay City PNP authorities are conducting investigation on the mysterious death of a 19-year-old male found in Purok Sigay, Barangay Zone 3, Talisay City around 7:00 a.m. Sunday. The victim was later identified by police authorities, according to Superintendent Adonis Rosales, as Orlando Salazar Jr., whose body was found in a nipa plantation in the area already in a state of decomposition. He sustained a lone hack wound on his back. According to his mother the victim was last seen roaming in the fish port two days before his body was found. Police also alleged that the victim had previous cases of theft in the village and was previously sniffing solvent.*Q: Do any Nikon FX cameras allow square-format shooting with DX lenses? When one uses a Nikon DX (APS-C) camera on an FX camera body, the camera automatically enters a "DX crop mode", using only the center portion of the sensor to match the DX format, as explained on Nikon's web site. The FX format is roughly 36×24mm, while DX is 24×16mm, and it's this smaller size that DX crop mode uses. Notice that the short edge of the FX format is equal to the long edge of DX — and of course the image circle is perfectly round, not oblong. Do any Nikon full-frame cameras allow a "square DX" format, either 24×24mm (with some possible vignetting in the extreme corners) or slightly reduced? A: Square format is not supported, but 5:4 aspect ratio offered by D3, D3s, D800 and D800E is only slightly wider, 30mm. The nice thing is that the viewfinder is electronically masked, so you can compose with good precision. This aspect ratio is not provided on a D700 or D3x. Alternatively, you could always crop in post. Of course, you'll also need to disable Auto DX Crop. The Blyth Hotel Simple yet stylish, the Blyth is contemporary seaside hospitality at its best; designed to be welcoming but informal, giving you the luxury of relaxing into Southwold living. A delightfully refurbished family run hotel just 5 minutes walk from Southwold’s famous colourful beach huts or the town centre. All of our 12 bedrooms with en-suite bath or shower, have been elegantly styled during a recent refurbishment. As a family run business, we offer attention to detail in every way and guarantee you’ll find it hard to leave.Headlines Bruins seek split of home-and-home vs. Sabres by Mike Battaglino / NHL.com SABRES (9-23-3) at BRUINS (23-10-2) TV: MSG-B, NESN Last 10: Buffalo 4-4-2; Boston 7-3-0 Season series: The Buffalo Sabres defeated the Boston Bruins 4-2 on Thursday after trailing 2-1 late in the second period. Boston won the first game, also at Buffalo, 5-2 on Oct. 23, with two third-period goals from defenseman Torey Krug. Big story: Buffalo has won two in a row in regulation for the first time this season; it has not won three in a row in any manner. Of the Sabres' nine wins, three are against the Bruins, Los Angeles Kings and San Jose Sharks (sixth, fourth and seventh in the NHL standings prior to Saturday). "I expect [Boston] to probably be a little upset about the loss," Sabres defenseman Mike Weber told the team website. "I think we've always played them hard and it's always been a hard-fought game. I'm not too worried about anything. It's always better when you're into the game when people are hitting you and you're hitting them back, and you're into the battles in front of the net." Team Scope: Sabres: Buffalo acquired forward Linus Omark in a trade Thursday and will put him to work Saturday. "He'll take a spot in the lineup," interim coach Ted Nolan said Friday, according to the Buffalo News. "I'm not 100 percent sure exactly where we'll put him yet but he'll play tomorrow night." The Sabres are short a forward after Cody Hodgson sustained a wrist injury blocking a shot by Krug in the first period Thursday. Nolan said Hodgson would be out "maybe a week or two or three. I'm not sure." Omark, 26, played one game this season for the Edmonton Oilers, who received a conditional sixth-round draft pick in return. He was fourth in the American Hockey League with 29 points in 29 games for Oklahoma City. "He's getting pretty close," coach Claude Julien told the Boston Herald after practice Friday. "Honestly it's a matter of game-to-game right now. I don't know yet [about the game Saturday], but I wouldn't write him off." McQuaid hasn't played this month because of a lower-body injury reported to be a groin pull, missing eight games (5-3-0). The Bruins could wait until after the three-day Christmas break to give him a little more recovery time. "I hope that's not the case," McQuaid told the Herald. "I want to be back playing as soon as I can. I definitely don't want to be going through that cycle of coming back a little bit too soon [and getting hurt again]. But when I'm ready, I'll be ready. Hopefully that's sooner rather than later." Who's hot: The Sabres have killed 14 penalties in a row; they haven't allowed a power-play goal since Dec. 5. Forward Brian Flynn has three of his season's six points in the past two games. Forward Drew Stafford has three points in four games, including his first goal since Nov. 5. Defenseman Christian Ehrhoff has five points in the past six. … Bruins forward Brad Marchand had two goals Thursday, and defenseman Zdeno Chara had two on Tuesday. Forward David Krejci has 11 points in his past 10 games. Share this!! The NHL uses cookies, web beacons, and other similar technologies. By using NHL websites or other online services, you consent to the practices described in our Privacy Policy and Terms of Service, including our Cookie Policy.Independent UX Consultant & Mobile Specialist
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const selector = `${activeRowSelector} .monaco-editor .view-lines`; return this.code.waitForTextContent(selector, undefined, c => accept(c.replace(/\u00a0/g, ' '))); } async waitForMarkdownContents(markdownSelector: string, text: string): Promise<void> { const selector = `${activeRowSelector} .markdown ${markdownSelector}`; await this.code.waitForTextContent(selector, text); } async insertNotebookCell(kind: 'markdown' | 'code'): Promise<void> { if (kind === 'markdown') { await this.quickAccess.runCommand('notebook.cell.insertMarkdownCellBelow'); } else { await this.quickAccess.runCommand('notebook.cell.insertCodeCellBelow'); } } async deleteActiveCell(): Promise<void> { await this.quickAccess.runCommand('notebook.cell.delete'); } async focusInCellOutput(): Promise<void> { await this.quickAccess.runCommand('notebook.cell.focusInOutput'); await this.code.waitForActiveElement('webview, .webview'); } async focusOutCellOutput(): Promise<void> { await this.quickAccess.runCommand('notebook.cell.focusOutOutput'); } async executeActiveCell(): Promise<void> { await this.quickAccess.runCommand('notebook.cell.execute'); } async executeCellAction(selector: string): Promise<void> { await this.code.waitAndClick(selector); } } Attractive Distractions When the swell is right, nothing on earth could stop a surfer from surfing. It’s true what they say: the ocean is the place where boys become men and men become boys – again. It always depends on waves... „Attractive Distractions“ takes us on a journey to the best surf spots all around the world: Maui, Portugal, New Zealand, Mentawais Islands, Indonesia and Australia. Featuring: Albee Layer, Matt Meola, Kai Barger, John John Florence, Tyler Larronde, Dege O'Connell and Torrey Meister.import {chalkSuccess} from './chalkConfig'; /* eslint-disable no-console */ console.log(chalkSuccess('Starting app in dev mode...')); // // Room.h // Stillness // // Created by Robert Hodgin on 01/01/12. #pragma once #include "cinder/gl/Vbo.h" class Room { public: Room(); Room( const ci::Vec3f &dims, bool isPowerOn, bool isGravityOn ); void init(); void updateTime(); void update(); void draw(); void setDims( const ci::Vec3f &dims ){ mDims = dims; }; ci::Vec3f getDims(){ return mDims; }; ci::Vec3f getRandCeilingPos(); ci::Vec3f getCornerCeilingPos(); ci::Vec3f getCornerFloorPos(); float getFloorLevel(); float getCeilingLevel(); void adjustTimeMulti( float amt ); float getTimePer(); float getTimeDelta(); bool getTick(); void togglePower(){ mIsPowerOn = !mIsPowerOn; }; float getPower(){ return mPower; }; bool isPowerOn(){ return mIsPowerOn; }; float getLightPower(); void toggleGravity(){ mIsGravityOn = !mIsGravityOn; }; ci::Vec3f getGravity(){ return mGravity; }; bool isGravityOn(){ return mIsGravityOn; }; ci::gl::VboMesh mVbo; // TIME float mTime; // Time elapsed in real world seconds float mTimeElapsed; // Time elapsed in simulation seconds float mTimeMulti; // Speed at which time passes float mTimeAdjusted; // Amount of time passed between last frame and current frame float mTimer; // A resetting counter for determining if a Tick has occured bool mTick; // Tick (aka step) for triggering discrete events // DIMENSIONS ci::Vec3f mDims; // Hesitant to rename this to 'bounds'. Might make it too easy to ci::Vec3f mDimsDest; // confuse with mRoomFbo.getBounds() which would return the Fbo Area. // POWER bool mIsPowerOn; // Power ranges from 0.0 to 1.0. float mPower; // GRAVITY ci::Vec3f mGravity; // Gravity vector ci::Vec3f mDefaultGravity; // The default Gravity vector, in case you want to mess with gravity // but always be able to get back to the original condition. bool mIsGravityOn; // For turning Gravity on and off };Весной этого года во многих СМИ появилась информация о том, что в селе Мокрая Ольховка Волгоградской области, обнаружены несколько окаменевших яиц динозавров. Так как данное село находится не так уж и далеко от моего города, то эта история меня сильно заинтересовала, и я решил собственными глазами увидеть эти «яйца». Отчет о поездке и свои мысли по этому поводу, я и предлагаю вашему вниманию.Я по натуре скептик и если честно, не ожидал увидеть что то особенное. Думал, что это просто очередной трюк с целью привлечь как можно больше туристов. Но весь мой скептицизм улетучился уже после первого разговора с местным жителем, который согласился проводить до места находок. С горящими глазами он рассказал мне, как после проливных дождей в одном из оврагов, близ села были обнаружены странные объекты сферической формы и как сразу же была выдвинута версия о том, что это окаменевшие яйца динозавров.Вскоре я и сам смог присмотреться к этим «яйцам» поближе. Все они примерно одного размера — около метра в диаметре и столько же в высоту. Состоят из кремния, песка и металла, что сразу заставило меня отбросить версию о динозаврах. На некоторых отчетливо видны следы коррозии — это еще раз подтверждает, что в их состав входит какой то металл.Несколько «яиц» оказались расколотыми и можно было увидеть, что они полые внутри. Причем в каждом, находилась некая смесь мелкого песка с гранулированным металлом. В общем поездка только добавила загадок и не д
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ability to associate rewards with contextual cues; however, the mechanism was unclear. We hypothesized that this enhancement of VTA firing was the mechanism by which DAT and dopamine release was altered to enhance cocaine effects and concomitant reward processing. Using male and female *TH-BAC-Cre* mice combined with viral expression of Cre-dependent excitatory designer receptors exclusively activated by designer drugs (excitatory DREADDs: hM3Dq) we were able to use clozapine-N-oxide (CNO) to enhance VTA dopamine neuron firing selectively in males and dioestrus females ([Fig. 5a](#f5){ref-type="fig"})[@b48][@b49]. We find that oestrus females, compared with dioestrus females and males release two times more dopamine to single-pulse tonic stimulations in the NAc ([Fig. 5b,c](#f5){ref-type="fig"}). However, when VTA dopamine neuron firing is chemogenetically increased specifically during dioestrus, dopamine release was increased compared with control dioestrus females and males, and not different from oestrus females ([Fig. 5b,c](#f5){ref-type="fig"}). Furthermore, enhancing basal VTA firing is sufficient to increase male and dioestrus female\'s responsivity to phasic stimulation parameters to match those of oestrus females ([Fig. 5b,d](#f5){ref-type="fig"}). The ability of cocaine to inhibit DAT (apparent *K*~m~) and elevate dopamine levels is increased in oestrus females ([Fig. 5e--g](#f5){ref-type="fig"}). When excitatory DREADDs are used to enhance selectively VTA dopamine neuron firing in dioestrus females and males, the ability of cocaine to inhibit DAT is increased to the levels of oestrus females ([Fig. 5f,g](#f5){ref-type="fig"}). CNO alone in mice that did not express DREADDs did not affect any of these measures, further highlighting that the effects were due to DREADD-induced increases in VTA activity ([Supplementary Fig. 16](#S1){ref-type="supplementary-material"}). This is concomitant with a threefold increase in the affinity for cocaine to bind to DAT ([Fig. 4g](#f4){ref-type="fig"}). These data demonstrate that enhancement of VTA firing is sufficient to induce changes in protein function that alter substrate binding. In addition, cocaine-induced dopamine release is increased in oestrus females. Thus, increasing VTA firing during dioestrus recapitulates both the basal dopamine function and effects of cocaine seen during oestrus. To determine whether the increased VTA dopamine activity associated with the oestrus cycle is causal to enhanced reward processing, we increased VTA dopamine activity in *TH-BAC-Cre* male, dioestrus female and oestrus female mice during cocaine conditioning using excitatory DREADDs ([Fig. 5h](#f5){ref-type="fig"}). The formation of CPP in CNO-treated dioestrus females and males is increased to levels similar of oestrus females ([Fig. 5i](#f5){ref-type="fig"}). However, when this same experiment was done in oestrus females, CNO was not able to further potentiate cocaine CPP. This provides additional support for the idea that downstream changes in reward processing and CPP are mediated by activity-dependent alterations in dopaminergic projections from the VTA to the NAc ([Fig. 6](#f6){ref-type="fig"}). Discussion ========== We define a mechanism by which a selective increase in drug potency during oestrus leads to long-lasting associations that enhance drug responses in female mice even outside of the oestrus phase. First, we identify a mechanism for the enhanced cocaine reward exhibited in oestrus females by showing that cocaine affinity for DAT is enhanced during oestrus. Levels of circulating estradiol were correlated with cocaine potency highlighting its role in the process. This enhances dopaminergic responses to both cocaine and reward cues, leading to VTA-NAc responses to the environmental cues alone, in the absence of drug, even at later stages in the oestrous cycle. Second, we determined the mechanism by which the DAT is altered to have a higher affinity for cocaine binding. Oestrous cycle-dependent enhancement of VTA firing leads to activity-dependent changes at the level of DAT that enhanced cocaine potency and subsequent cue-reward associations for cocaine. This enhanced dopaminergic function paired with enhanced cocaine action directly at its site of action lead to potent and long-lasting associations between drugs and associated cues that likely enhance motivation, drug-seeking and relapse, even in the absence of drug. Together, these data provide a basic mechanism whereby increased VTA firing drives adaptations to DAT that increase cocaine potency at DAT and increase cocaine reward. Previous work using anaesthetized *in vivo* voltammetry and microdialysis has shown that cocaine increases extracellular dopamine levels to a greater extent in oestrus females as compared with females in dioestrus; however, the mechanism for this effect was unclear and was suggested to be mediated selectively via effects on dopamine release[@b50]. Here we show that these increases in cocaine\'s ability to increase dopamine levels in reward-related brain regions are due to an increase in cocaine\'s ability to bind to and inhibit DAT. Although dopamine release was also increased, a finding that is consistent with a large body of previous work, we found that the enhanced release was not predictive of changes in cocaine\'s ability to inhibit uptake; thus, the two phenomena were dissociable. Further, the magnitude of cocaine\'s effects on the dopamine system was predictive of CPP, showing that this enhanced ability to inhibit DAT probably leads to increased associations between the rewarding properties of cocaine and the contextual cues that predicted its availability. These data could also explain the increased acquisition and drug consumption that is seen during oestrus in animals voluntarily self-administering cocaine[@b51][@b52]. As the effects we observed were oestrous cycle dependent, we hypothesized that they were driven by circulating levels of ovarian hormones. To this end, we determined serum levels of estradiol and progesterone within each subject and found that the increase in cocaine potency at DAT was highly correlated with estradiol, but not progesterone levels. Previous work in ovariectomized rodents has shown that systemic delivery of estradiol, but not progesterone, increases cocaine consumption and motivation, suggesting that these changes in cocaine potency could be the molecular mechanism by which these behavioural effects occur[@b53][@b54]. Further, we determined where these hormone-induced changes in cocaine potency on dopamine terminals originated. We bath applied estradiol directly to slices containing the NAc. These coronal slices contained dopamine nerve terminals originating in the VTA, but disconnected from their associated VTA cell bodies. We found that estradiol did not affect baseline dopamine nerve terminal function or cocaine potency in any of the groups tested, suggesting that the changes in the function of the dopamine terminal originated upstream. The hypothesis that upstream changes at the level of the cell body in the VTA drive this process was supported by data showing that enhancement of VTA activity via DREADDs was able to change the dopamine terminal and enhance cocaine reward in male and dioestrus female mice. Thus, together we hypothesize that during oestrus increases in VTA firing lead to downstream, activity-dependent signalling that alters DAT. Increasing VTA dopamine activity via excitatory DREADDs increased both the affinity of cocaine for DAT and the formation of CPP in males and dioestrus females. We found that these changes in cocaine effects at DAT were concomitant with increased DAT phosphorylation at Thr53. In fact, Thr53 phosphorylation has been linked to both activity-dependent changes in uptake function and alterations in stimulant efficacy at the transporter[@b34]. Increasing ERK activity leads to Thr53 phosphorylation, enhanced uptake rates and enhanced stimulant effects at the DAT[@b36][@b37][@b38][@b39][@b40]. Further, previous work has shown that cellular depolarization and activity is sufficient to increase ERK activity[@b55], providing a link between enhanced DAT phosphorylation, and increases neuronal activity. Indeed, here we show that during oestrus phosphorylated ERK levels are increased, and that this increase is directly correlated with DAT phosphorylation at Thr53. Further work is needed to establish causal connections between Thr53 phosphorylation and oestrous cycle-dependent fluctuations in reward processing. One important finding to support this hypothesis was the lack of further increases in cocaine potency in oestrus females expressing excitatory DREADDs. The occlusion of activity-dependent changes in cocaine effects was observed not only at the level of the dopamine terminal, but also in regard to the development of CPP. Although this is not definitive proof, this occlusion strongly suggests that these two effects are probably occurring through similar molecular mechanisms. Further, these data are important, because these molecular adaptations drive strong cue-reward associations that extend past the oestrus stage. Thus, it seems that when the cues are associated may play a large role in determining the subsequent response to cues. The ability to associate rewards with cues that predict their availability is critical to survival, as these cues can result in the motivation to obtain rewards such as food and underlie the motivation to reproduce[@b41]. However, drugs of abuse hijack natural reward-learning processes, with associative learning contributing not only to the increased motivation to administer drugs of abuse such as cocaine, but also to relapse in both humans and animal models[@b44][@b45]. Greater cocaine effects on this pathway are associated with the compulsive drug-seeking and taking that develops over time and characterizes an addicted state[@b56]. Results of the present study show that oestrous cycle-dependent enhancement of reward circuitry and cocaine effects directly on this system lead to potent and long-lasting associations between the
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!" "So you have got a job." "Get married." "Oh come on!" "Don't speak nonsense." "Why, does it hurt your prestige?" "I did not get the job." "Gobra is bogus..." "Why are you putting a job in the way of marriage?" "A job you will get." "However, marriage..." "Don't be silly." "I am not sure as to how to earn my bread." "Look, if you don't mind..." "If you have that in mind then the population in Calcutta would not have exploded thus." "It is not possible to arrange your bread and then marry, especially in cases of a love marriage." "It just happens." "You will never be able to do anything." "If you got the job, would all your problems be gone?" "These are all working people." "However they are all due to be axed." "They all seem relaxed, don't they?" "Otherwise, why would a person like me walk seven miles for a meeting?" "Give something." "Anything." "This is not on credit." "This is a subscription." "Here in this box." "You have to form groups to survive in this market." "Coming to the meeting?" "No!" "Let me first tackle the meeting at home!" "I will go that way." "You will have to change your course one day, my king!" "For sale!" "Would you like to buy some mud?" "I am bound to tell you." "I had been frantically searching for Ram Babu." "It is already two months." "How long must I wait?" "OK." "I will try to send your money as soon as possible." "Yes, please do that." "Otherwise I will have to disconnect the electricity." "I do not want to do those things." "In fact, that was exactly why I told the gentleman from the very beginning" "To maintain a professional relationship with people." "Otherwise people all over would become so friendly that..." "Oh!" "So you could not wait to hear what I was saying." "All right." "Where had you been?" "I was roaming." "I did something at least." "One feels so lazy in the afternoons." "I also feel the same." "Did you have lunch?" "Yes." "How did you?" "Mother cooked whatever rice was there." "Oh!" "Sita..." "Ramu has not returned?" "He did not eat anything." "I cooked whatever rice was left." "I saved this rice so painstakingly." "But he did not eat." "Now all the rice has gone to waste." "If the ration does not come this morning the cards will lapse." "He has gone out early this morning to arrange for money." "He has no concern for the family, makes no real effort to get a job." "Even in such extreme poverty, he is only concerned about his own..." "Why are you speaking so loudly?" "Because I wish to." "What the hell are you going to eat tonight?" "I feel suffocated." "The lad is loitering like a vagabond in this sun." "Neither has he any work, nor anything to eat." "What to do?" "I cannot even go away." "India's Natural Resources..." "What is the price?" "One Rupee." "Sit down." "The sky is looking so lovely through the leaves?" "Mother was saying that if the ration is not fetched by today, the cards will lapse." "I had been roaming about frantically since morning for money." "I even knocked Susanto thrice." "The scene is the same everywhere." "I have arranged for some money." "Shall I give it?" "Give it to mother." "All right." "I'm leaving..." "I have already told you." "I would take you there." "Really!" "No!" "You go now." "Come." "Mother is not at home." "Sister is on the terrace... alone." "The place is excellent." "Your pain in the heart is still there!" "Do not try to hide." "Concealing it will not help anyone." "If you cannot go by yourself, why don't you send Shefali?" "Some money could have been arranged from somewhere." "Leave it for the time being." "Why?" "And that Shefali seems to be changing these days." "You must keep watch." "If any arrangement could have been made, then of course..." "You appear to have become so aloof from everything." "What's the matter?" "Please leave me alone." "Oh!" "The relationship is becoming old!" "Can't you understand?" "Don't you feel any needs?" "Don't you feel like breaking off after days of loitering?" "Don't you feel like leaving everything?" "Uma!" "Yes, I want a break." "But I cannot get it." "There is no break." "There is no break from this vicious circle." "Unless you make a reckless dive, there is no break." "How are we going to live?" "You have brought the card for Sagar Babu?" "Yes." "We had to be humiliated thus." "How horrible!" "What?" "No, nothing." "Is Sagar Babu in that room?" "Yes..." "'India's Natural Resources'." "I could not keep from buying this book after seeing it in the shop." "One can get an idea of the sorrow and misery around by reading this book." "These sorrows, these miseries are so meaningless and irrelevant." "India has such rich mineral resources." "One word..." "It can be said here itself." "We have got your monthly rent of Rs. 50 in due time." "Yes." "So were you due to pay anything today?" "Credit." "Credit!" "You know very well that this credit would never be repaid!" "Still..." "I mean..." "I do not understand." "We will have had nothing to eat tonight." "Sita, you are crossing your limits..." "I am dying of my own problems." "I love seeing this picture from time to time." "So, you have come to this room..." "Why?" "Now he has taken the responsibility of the family." "No, I was joking." "However, what I said is serious." "You did not have anything to eat for the whole day." "Brother!" "Susanto da is calling." "Brother, the landlord came today." "He has asked for a deadline." "Why did you not ask for another 15 odd days?" "Come Sagar, let's go for dinner." "Here..." "I knocked at your home thrice." "I went for money to buy the ration." "I have arranged for about ten rupees on condition of it being returned within seven days." "What's up?" "Better you had not brought the money than bringing it on condition!" "You somewhat cannot manage to get anything, can't you?" "The need for money in the house has been met." "Brother was speaking of a job offer in his office." "While I have decided to sacrifice my life for my country, why don't you give a try?" "The interview is tomorrow." "What do you think?" "Will I get it?" "Just try your luck." "I have been spending my life with the hope that luck would shine." "For god's sake, ask your brother for a recommendation." "I told you... brother will be trying." "Give me the money." "I will repay it as soon as I get the job." "Yet how afar would thou take me oh beautiful one." "On which bank would stop thy golden boat?" "Please play the other tune once more!" "Situ..." "Have you finished?" "I have finished, brother." "Just check whether the ironing is OK." "It will do" "Be quick." "I will have to give a nice interview today." "Maybe, this would just turn out to be the ladder." "Or maybe..." "Or even, definitely..." "I have bought meat." "I have almost forgotten the taste of good food cooked by you." "Did you spend the entire money, son?" "Who said so?" "Here, take it." "Today's marketing has been on my money mother... on my money!" "I will give one slap on your head." "Pintu, Pintu..." "Why?" "I would ask him to buy some curds." "He is going for some good work." "So, I must bless him." "Oh." "I predict that no one would be able to stop brother from getting the job today!" "I will surely convert that blessing into a major victory today!" "Pintu, Pintu..." "Wonder where he is!" "Do you go for work?" "How did you understand?" "Because you do not stay at home in the afternoons!" "Yes..." "Sister..." "Sister has no work." "Sister is like that." "Yesterday night she was crying by mother." "What is this?" "Paper." "What was your sister saying?" "She was saying that she did not want to hurt mother." "What is written in these papers?" "Formula." "Formula?" "Yes, I mean formula for an insecticide." "Whether lime or sulphur in tea leaves..." "I will discuss these things with you later." "When we grow up... all right?" "You will have to wait." "Why?" "Brother was saying that some new boss is coming to take the interview." "So the sound of the clock has already started to bug you?" "I have a meeting at Metiabruz." "
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ated/gulp-jade) - [Jade](https://github.com/pugjs/jade) → HTML. - [gulp-handlebars](https://github.com/lazd/gulp-handlebars) - [Handlebars](https://github.com/wycats/handlebars.js) templates → JavaScript. - [gulp-hb](https://github.com/shannonmoeller/gulp-hb) - [Handlebars](https://github.com/wycats/handlebars.js) templates → HTML. - [gulp-nunjucks](https://github.com/sindresorhus/gulp-nunjucks) - [Nunjucks](https://github.com/mozilla/nunjucks) templates → JavaScript. - [gulp-dustjs](https://github.com/sindresorhus/gulp-dust) - [Dust](https://github.com/linkedin/dustjs) templates → JavaScript. - [gulp-riot](https://github.com/e-jigsaw/gulp-riot) - [Riot](https://github.com/riot/riot) templates → JavaScript. - [gulp-markdown](https://github.com/sindresorhus/gulp-markdown) - Markdown → HTML. - [gulp-template](https://github.com/sindresorhus/gulp-template) - [Lodash](https://github.com/lodash/lodash) templates → JavaScript. - [gulp-swig](https://github.com/colynb/gulp-swig) - [Swig](https://github.com/paularmstrong/swig) templates → HTML. - [gulp-remark](https://github.com/denysdovhan/gulp-remark) - Gulp plugin for [remark](https://github.com/wooorm/remark) - markdown processor powered by plugins ### Linting - [gulp-csslint](https://www.npmjs.com/package/gulp-csslint) - Automated linting of CSS with [CSSLint](https://github.com/CSSLint/csslint). - [gulp-htmlhint](https://github.com/bezoerb/gulp-htmlhint) - [HTMLHint](https://github.com/yaniswang/HTMLHint) wrapper to validate your HTML. - [gulp-jshint](https://github.com/spalger/gulp-jshint) - Detect errors and potential problems in JavaScript with [JSHint](https://github.com/jshint/jshint). - [gulp-jscs](https://github.com/jscs-dev/gulp-jscs) - Check JavaScript code style with [jscs](https://github.com/jscs-dev/node-jscs). - [gulp-coffeelint](https://github.com/janraasch/gulp-coffeelint) - A style checker that helps keep [CoffeeScript](https://github.com/jashkenas/coffeescript) code clean. - [gulp-tslint](https://github.com/panuhorsmalahti/gulp-tslint) - [TypeScript](https://github.com/Microsoft/TypeScript) linter plugin for gulp. - [gulp-eslint](https://github.com/adametry/gulp-eslint) - Identify and report on patterns found in ECMAScript/JavaScript code. - [gulp-w3cjs](https://github.com/callumacrae/gulp-w3cjs) - Validate HTML with [w3cjs](https://github.com/thomasdavis/w3cjs). - [gulp-lesshint](https://github.com/lesshint/gulp-lesshint) - Lint less files with [lesshint](https://github.com/lesshint/lesshint). - [gulp-check-unused-css](https://github.com/zalando/gulp-check-unused-css) - Check your HTML templates for unused CSS classes. ### Live Reload - [browser-sync](https://github.com/BrowserSync/browser-sync) - Keep multiple browsers & devices in sync when building websites ([recipes](https://github.com/BrowserSync/gulp-browser-sync)). - [gulp-livereload](https://github.com/vohof/gulp-livereload) - Gulp plugin for livereload. ### Caching - [gulp-changed](https://github.com/sindresorhus/gulp-changed) - Only pass through changed files. - [gulp-cached](https://github.com/contra/gulp-cached) - A simple in-memory file cache. - [gulp-remember](https://github.com/ahaurw01/gulp-remember) - Remember and recall files passed through it. - [gulp-newer](https://github.com/tschaub/gulp-newer) - Pass through newer source files only. ### Flow Control - [merge-stream](https://github.com/grncdr/merge-stream) - Merge multiple streams into one interleaved stream. - [streamqueue](https://github.com/nfroidure/StreamQueue) - Pipe queued streams progressively. - [run-sequence](https://github.com/OverZealous/run-sequence) - Run a series of dependent gulp tasks in order. - [gulp-if](https://github.com/robrich/gulp-if) - Conditionally run a task. ### Logging - [gulp-notify](https://github.com/mikaelbr/gulp-notify) - Notification plugin for gulp. - [gulp-size](https://github.com/sindresorhus/gulp-size) - Display the size of your project. - [gulp-debug](https://github.com/sindresorhus/gulp-debug) - Debug vinyl file streams to see what files are run through your gulp pipeline. - [gulp-beer](https://github.com/lordgiotto/gulp-beer) - Better Error Reporting with interactive system notifications and custom server for error displaying. ### Testing - [gulp-mocha](https://github.com/sindresorhus/gulp-mocha) - Run [Mocha](https://github.com/mochajs/mocha) tests. - [gulp-jasmine](https://github.com/sindresorhus/gulp-jasmine) - Run [Jasmine 2](https://github.com/jasmine/jasmine) tests in Node.js. - [gulp-protractor](https://github.com/mllrsohn/gulp-protractor) - Gulp wrapper for [Protractor](https://github.com/angular/protractor) tests. - [gulp-coverage](https://github.com/dylanb/gulp-coverage) - Coverage reporting for Node.js that is independent of the test runner. - [gulp-karma](https://github.com/karma-runner/gulp-karma) - Karma test runner for gulp. - [gulp-ava](https://github.com/sindresorhus/gulp-ava)- Run [AVA](https://github.com/sindresorhus/ava) tests with gulp. ### Miscellaneous Plugins - [gulp-util](https://github.com/gulpjs/gulp-util) - Set of useful utilities. - [gulp-plumber](https://github.com/floatdrop/gulp-plumber) - Prevent pipe breaking caused by errors. - [gulp-load-plugins](https://github.com/jackfranklin/gulp-load-plugins) - Automatically load in gulp plugins. - [main-bower-files](https://github.com/ck86/main-bower-files) - Simplify build process setup by dynamically getting the library files. - [autoprefixer](https://github.com/postcss/autoprefixer) - Parse CSS and add vendor prefixes to rules by Can I Use. - [gulp-sourcemaps](https://github.com/floridoo/gulp-sourcemaps) - Provide source map support. - [gulp-replace](https://github.com/lazd/gulp-replace) - A string replace plugin for gulp. - [gulp-rename](https://github.com/hparra/gulp-rename) - Rename files easily. - [gulp-rev](https://github.
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is believes this to have something to do with a mistake he made in the past, with his previous wife: she miscarried their first child and when Cornelis asked the doctor to save the second child over the wife, he feels that God punished him by taking both his wife and his child away. Cornelis decides to hire a painter, so that he could at least be remembered as having had a beautiful young wife, should he have no heir to continue his legacy. Sophia agrees, but as soon as the young painter Jan arrives to paint the couple, he and Sophia fall in love. Jan sends a note to Sophia, asking her to send him a vase with tulips. She shows up at his door with the tulips, and they consummate their love. Meanwhile, Sophia's friend, the housemaid Maria, is in a courtship with the neighborhood fishmonger, Willem. Willem is speculating in the tulip market, and is doing quite well - expecting to be independently prosperous and able to marry Maria, he even sells his business to another fishmonger. One day, Sophia borrows Maria's cloak and heads to a rendezvous with Jan. Willem, seeing Sophia in the cloak, mistakes her for Maria, and follows her to her rendezvous. Crushed by what he thinks is Maria's unfaithfulness, he goes to a pub to drown his sorrows. There a prostitute robs him of the large sum of money he has built up on the tulip market. When he tries to retrieve the money, he is beaten up and forcibly inducted into the navy for causing a ruckus. Jan plots to escape to the new world with Sophia, after having success of his own in the tulip speculation market. He hears that the nuns at St. Ursula (the convent Sophia came from) raise tulips in their gardens. Jan attempts to steal some of the bulbs, but is knocked out by the abbess of St. Ursula. When he regains consciousness, he apologises and the abbess gives him the bulbs Willem had bought before he was thrown into the navy. Maria realizes that she is pregnant with Willem's child. With Willem gone, the baby will be born out of wedlock. Maria explains her condition to Sophia and threatens to reveal Sophia's affair to Cornelis, if Cornelis were to find out about her pregnancy. Sophia conspires with Maria and decides to pass off the pregnancy as her own. When the baby is born, Sophia will pretend to die in childbirth, so she can leave to be with Jan, and Maria will get to raise the child as her own with Cornelis. After Maria gives birth to a daughter and Sophia pretends to die, Cornelis is griefstricken at the loss of his wife. Sophia, under her shroud, weeps as she realizes that she has deeply hurt Cornelis with her deceit, but eventually realizes that it is too late to undo what she has done. Ashamed of herself, Sophia runs away and Jan is unable to find her. Willem, returning after his stint in the navy, goes to see Maria at Cornelis's house. Maria is furious at him at first, but they soon reconcile. Cornelis overhears their loud quarreling and the reveal of the conspiracy between Maria, Sophia, and Jan. Cornelis makes his peace with the truth, and departs for the Indies, where he finds love and makes a family, but only after first leaving the house to Maria, Willem, and the baby girl that he loved as his own. Eight years later, the abbess of St. Ursula visits Jan and views his artwork of Sophia. She praises him for his talent, and commissions him to paint a mural in the church. When Jan looks down from painting the mural, he sees Sophia, who has joined the convent, and they share tender smiles. Cast Dane DeHaan as Jan van Loos, a painter Alicia Vikander as Sophia Sandvoort, orphaned wife to a wealthy merchant Christoph Waltz as Cornelis Sandvoort, a wealthy peppercorn merchant Jack O'Connell as Willem Brok, a fishmonger Holliday Grainger as Maria, the Sandvoorts’ maid Judi Dench as the Abbess of St. Ursula Zach Galifianakis as Gerrit, assistant to Jan Matthew Morrison as Mattheus, a friend and associate of Jan Cara Delevingne as Annetje, a tulip trader and petty thief Joanna Scanlan as Mrs. Overvalt, a dressmaker Tom Hollander as Dr. Sorgh, a physician Cressida Bonas as Mrs. Steen, an old friend of Cornelis and Sophia Kevin McKidd as Johan de Bye, a tulip trader David Harewood as Mr. Prater, a representative of St. Ursula’s Convent Production The film was originally planned to be made in 2004 on a $48 million budget, with Jude Law, Keira Knightley and Jim Broadbent as lead actors, John Madden as director and Steven Spielberg producing through DreamWorks. However, the production was halted days before it was scheduled to start filming as a result of changes in tax rules affecting film production in the UK. On July 8, 2013, the Daily Mail's Baz Bamigboye reported that Justin Chadwick would direct the film with Alicia Vikander attached to star in the role of Sophia and that Matthias Schoenaerts was being sought for the male lead. Bamigboye reported that Chadwick together with producers Alison Owen and Harvey Weinstein, decided to cast Vikander for the film. In 2014, Alison Owen partnered with Weinstein to restart the film after re-acquiring the rights to the film from Paramount Pictures. In October 2013, Dane DeHaan was in talks to join the cast. In February 2014, Christoph Waltz joined the cast. In April 2014, Holliday Grainger, Cara Delevingne, and Jack O'Connell joined the cast. In June 2014, Judi Dench was cast as the abbess of St. Ursula, who takes in orphaned children. That same month Tom Hollander, Cressida Bonas, and David Harewood joined the cast. In August 2014, Matthew Morrison joined. Deborah Moggach, author of the novel, also appears in the film. Harvey Weinstein offered Harry Styles the role of Mattheus, but the singer turned it down due to scheduling conflicts, and Matthew Morrison was cast instead. The crew of Tulip Fever included cinematographer Eigil Bryld, production designer Simon Elliott, costume designer Michael O’Connor, hair and make-up designer Daniel Phillips and editor Rick Russell. Tom Stoppard adapted the screenplay for the film. The London-based Welsh portrait artist Jamie Routley did the original portraits that are seen in the film. Danny Elfman composed the film's score. Filming took place at Cobham Hall in Gravesend, Kent where production transformed a wing at the school into a 17th-century Amsterdam Gracht. The waterway was also constructed from scratch, complete with barges and donkeys crossing humpback bridges. Additionally, the school's courtyard was used as the brewery yard in the story. Other filming locations include Norwich Cathedral, Holkham (in Norfolk), Tilbury (in Essex), Kentwell Hall (in Suffolk), and at Pinewood Studios on various dates throughout June and July in 2014. Filming also took place in Haddenham, Buckinghamshire. Release Footage from the film was screened in May 2015 at the 68th Cannes Film Festival. In December 2015, the first image of the film featuring Alicia Vikander and Christoph Waltz was released. The film was originally scheduled to be released in November 2015, but was pushed back to July 15, 2016 and then delayed again until February 24, 2017. It was then pulled from the schedule, and later moved to August 25, 2017. On August 16, 2017, the film was again delayed, this time being pushed back a week to September 1. The film premiered on August 13, 2017, at London's Soho House. Box office , Tulip Fever has grossed $2.4 million in the United States and Canada and $5.9 million in other territories for a total of $8.3 million, against a production budget of $25 million. In North America, Tulip Fever was projected to gross $1–2 million from 765 theaters in its opening weekend. It ended up debuting to $1.2 million ($1.5 million over the four-day Labor Day weekend) in what was the worst combined holiday weekend since 1998. Despite adding seven theaters in its second weekend, the film dropped 75.4% to $285,300, the 37th biggest such drop in history. Critical response On review aggregator Rotten Tomatoes, the film has an approval rating of 10% based on 59 reviews, with an average rating of 4.4/10. The site's critical consensus reads, "Tulip Fever is a lush, handsomely-mounted period piece undone by uninspired dialogue and excessive plotting." On Metacritic, which assigns a normalized average rating to reviews, the film has an average score of 38
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good. The Prince hasn't had much to do for a long time. He'll be happy to have a new friend. Make sure you treat him nicely, he's a bit delicate now, poor thing." "I will," Jay promised. "Are you really old, as well?" "Older than most people you've ever met, but nothing like as antique as good old Trace, here." "Huh," Tracy sniffed critically. "If you're quite finished." Richard rolled his eyes for Jay's benefit. "Sweet dreams, Jay. I'll see you tomorrow, we've got lots to talk about." "Richard," Tracy asked reluctantly. "Did Calvert do it?" A huge smile flashed over his face. "Oh yeah. He did it. The Alchemist is neutralized. Just as well, it was a brute of a weapon." "Typical. If they'd just devote ten per cent of their military budget and all that ingenuity into developing their social conditions." "Preaching to the converted!" "Are you talking about Joshua?" Jay asked. "What's he done?" "Something very good," Richard said. "Amazingly," Tracy muttered dryly. "But . . ." "Tomorrow, sweetie," Tracy said firmly. "Along with everything else. I promise. Right now, you're going to bed. Enough delaying tactics." Richard waved, and walked away. Jay held Prince Dell against her tummy as Tracy's hand pressed into her back, propelling her up the steps and into the chalet. She glanced down at the ancient bear again. His dull glass eyes stared right back at her, it was an incredibly melancholic expression. The first hellhawk came flashing out of its wormhole terminus twelve thousand kilometres from Monterey asteroid. New California's gravitonic detector warning satellites immediately datavised an alert to the naval tactical operations centre. The high pitched audio alarm startled Emmet Mordden, who was the duty officer in the large chamber. At the time he was sitting with his feet up on the commander's console, reading through a four-hundred-sheet hard copy guide of a Quantumsoft accountancy program in preparation for his next upgrade to the Treasury computers. With most of the Organization fleet away at Tranquillity, and the planet reasonably stable right now, it was a quiet duty, just right to catch up on his technical work. Emmet's feet hit the floor as the AI responsible for threat analysis squirted a mass of symbols and vectors up on one of the huge wall-mounted holoscreens. In front of him, the equally surprised SD network operators scrambled to interpret what was happening. There weren't many of them among the eight rows of consoles in the centre, nothing like the full complement which the Organization had needed at the height of the Edenist harassment campaign. Right now, spaceflight traffic was at a minimum, and the contingent of Valisk hellhawks on planetary defence duty had done a superb job of clearing Edenist stealth mines and spy globes from space around the planet. "What is it?" Emmet asked automatically; by which time another three wormholes had opened. The precariously-stacked pile of hard copy avalanched off his console as he determinedly cleared his keyboard ready to respond. The AI had acquired X-ray laser lock on for the first four targets, and was requesting fire authority. Another ten wormholes were opening. Jull von Holger, who acted as the go-between for the Valisk hellhawks and the operations centre, leapt to his feet, shouting: "Don't shoot!" He waved his arms frantically. "They're ours! They're our hellhawks." Emmet hesitated, his fingers hovering over the keys. According to his console displays, over eighty wormholes had now opened to disgorge bitek starships. "What the fuck do they think they're doing busting in on us like that? Why aren't they with the fleet?" Suspicion flowered among his thoughts; and he didn't care that von Holger could sense it. Hellhawks were dangerously powerful craft, and with the fleet away they could make real trouble. He'd never really trusted Kiera Salter. Jull von Holger's face went through a wild panoply of emotion- derived contortions as he conducted fast affinity conversations with the unexpected arrivals. "They're not from the fleet. They've come here directly from Valisk." He halted for a moment, shocked. "It's gone. Valisk has gone. We lost to that little prat Dariat." "Holy shit," Hudson Proctor gasped. Kiera stuck her head round the bathroom door as the beautician tried to wrap her sopping wet hair in a huge fluffy purple towel. The Quayle suite in the Monterey Hilton was a temple to opulence and personal luxury. As Rubra had denied everyone access to the Valisk starscrapers, along with their apartment bathrooms, Kiera had simply groomed herself with energistic power alone. She had forgotten what it was to sprawl in a Jacuzzi with a selector that could blend in any of a dozen exotic salts. And as for having her hair styled properly rather than forcing it into shape . . . "What?" she snapped in annoyance; though the beacon-bright dismay in her associate's mind tempered any real fury at being interrupted. "The hellhawks are here," he said. "All of them. They've come from Valisk. It's . . ." He flinched in trepidation. Delivering bad news to Kiera was always a desperately negative career move. Just because she had the kind of teenage-sweetheart looks which could (and had) suckered in non-possessed kids from right across the Confederation didn't mean her behaviour matched. Quite the opposite — she took a perverse enjoyment from that, too. "Bonney chased after Dariat, apparently. There was a big fight in one of the starscrapers. Plenty of our people got flung back into the beyond. Then she forced him to ally with Rubra, or something." "What happened?" "They, er — Valisk's gone. The two of them took the habitat out of the universe." Kiera stared at him, little wisps of steam starting to lick out of her hair. She'd always bitterly regretted that Marie Skibbow didn't have some kind of affinity faculty; its absence had always put her at a slight disadvantage in Valisk. But she'd coped, the entire worldlet and its formidable starships had belonged to her. She'd been a power to contend with. Even Capone had sought out her help. Now — Kiera gave the non-possessed beautician girl a blank-eyed glance. "Get lost." "Ma'am." The girl curtseyed, and almost sprinted for the suite's double doors on the other side of the lounge. Kiera allowed herself a muted scream of fury when the doors closed. "That fucking Dariat! I knew it! I fucking knew he was a disaster waiting to happen." "We're still in charge of the hellhawks," Hudson Proctor said. "That gives us a big chunk of Capone's action; and the Organization is in charge of a couple of star systems, with more on the way. It's not such a loss. If we'd been inside the habitat it would be one hell of a lot worse." "If I'd been inside, it would never have happened," she snapped back. Her hair was abruptly dry, and her robe blurred, running like hot wax until it became a sharp mauve business suit. "Control," she murmured almost to herself. "That's the key here." Hudson Proctor could sense her focusing on him, both her eyes and her mind. "Are you with me?" she asked. "Or are you going to ask good old Al if you can sign on as one of his lieutenants?" "Why would I do that?" "Because if I can't keep control of the hellhawks, I'm nothing to the Organization." She smiled thinly. "You and I would have to start right back at the beginning again. With the hellhawks obeying us, we'll still be players." He glanced out of the big window, searching space for a sight of the bitek starships. "We've got no hold on them any more," he said dejectedly. "Without the affinity-capable bodies stored in Valisk, there's no way they'll do as they're ordered. And there aren't any more of Rubra's family left for us to replace them with. We've lost." Kiera shook her head impatiently. Considering she'd co-opted the ex-general to her council for his ability to think tactically, he was doing a remarkably poor job of it. But then, maybe a politician's instinct was naturally quicker at finding an opponent's weakness. "There's one thing left which they can't do for themselves." "And that is?" "Eat. The only sources of their nutrient fluid which they'll be able to use are on Organization-held asteroids. Without food, even bitek organisms will wither and die. And we know our energistic power can't magic up genuine food." "Then Capone will control them." "No." Kiera could sense his anxiety at the prospect of losing his status,
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Within-subjects changes in a 14-weeks usual care period were compared with changes in a 14-week functional power-training period (in groups, 3×/wk). Outcome measures were the muscle power sprint test (MPST), 1-minute walk test (1MWT), 10-m shuttle run test (SRT), gross motor function (GMFM-66), isometric strength of lower-limb muscles and dynamic ankle plantar flexor strength. Changes during the training period were significantly larger than changes in the usual care period for all outcome measures ( P < .05). Large improvements were found during the training period for walking capacity (ΔMPST [mean]: 27.6 W [95%CI 15.84-39.46, 83% increase], Δ1MWT: 9.4 m [95% CI 4.17-14.68, 13%], ΔSRT: 4.2 [95%CI 2.57-5.83, 56%], ΔGMFM-66: 5.5 [95% CI 3.33-7.74, 7%]) and muscle strength (18%-128%), while outcomes remained stable in the usual care period. The results indicate that functional power-training is an effective training for improving walking capacity in young children with cerebral palsy.This proposal addresses statistical issues arising from measurement error problems, with an emphasis on modeling within a Bayesian framework. Measurement error arises when a variable of interest, such as exposure to a contaminant, cannot be measured or is too expensive to measure for most subjects. Instead inference must based on a proxy variable measured with error, which can lead to incorrect conclusions if not properly addressed. This proposal is motivated by applications in environmental health studies, in which measurement error is often a problem. The specific aims are: (1) To delineate the advantages and disadvantages of Bayesian and frequentist approaches to measurement error problems using a case study approach; (2) Within a Bayesian framework, to examine the sensitivity of numerical estimates of the relationship between the outcome and covariates to their assumed distributions; (3) To develop a Bayesian paradigm for the 2-stage case- control design, and to compare numerical estimates with those from frequentist methods; and (4) To develop efficient sampling strategies for measuring the "gold standard" in a validation sub-study within a repeated measures setting. The research will be illustrated and applied to several datasets collected for environmental health studies.Internal stochastic resonance in two coupled liquid membrane oscillators. Internal stochastic resonance (ISR) is investigated in two coupled liquid membrane oscillators when only one oscillator is subjected to environmental noise in the absence of an external signal. Comparing the responses of both subsystems, it is found that enhancement or suppression of ISR for each oscillator depends on the coupling strength, that synchronization of the two oscillators can occur only at strong coupling strength, and that ISR without tuning can also occur under certain conditions in the above-mentioned models.>> Lost Worlds: Life in the Balance. According to Hulu, this 40-minute film is “An exploratory documentary that takes viewers to some of the most astonishing of Earth’s places” to provide “A global exploration of the fascinating interconnectedness of all living things.” >> Antartica. According to Hulu, “Filmmaker John Weiley explores the continent and its animals, as well as the scientists who work there” in this full-length movie. >> Big Ideas for a Small Planet. One full episode — “Power” — is available from this Sundance Channel eco-show. “Power” looks at alternative energy sources projects and the people working on them.Jazz on the Move: Celebrating 100 Years of Jimmy Van Heusen Sunday, January 20, 2013 7:00 PM Jazz on the Move: Celebrating 100 Years of Jimmy Van Heusen is in the past. The Nashville Jazz Workshop kicks off its seventh annual Jazz on the Move series with “Come Fly With Us: Celebrating 100 Years of Jimmy Van Heusen,” a program honoring the 100th birthday of the great composer, one of the most prolific songwriters in American history. The program takes place in Lipscomb’s Collins Alumni Auditorium on Sunday, January 20 at 3 p.m. Admission is free. This event will feature performances of Van Heusen’s best loved songs by the Lori Mechem Quartet with Duffy Jackson, Denis Solee, and guest vocalists Jeff Hall and Liz Johnson -- along with a lively and informative biography of the composer written by Ken Roberts and narrated by Don O. Henry. Jimmy Van Heusen (1913-1990) wrote songs for films, television and theater, and won an Emmy and four Academy Awards. Although his name is not a household word, his songs such as "Swinging on a Star," "Call Me Irresponsible" and "High Hopes" are instantly recognizable as popular standards. He is also revered in the jazz world for compositions such as "Here's That Rainy Day," "Polka Dots and Moonbeams," and "Like Someone in Love." He is most identified with Frank Sinatra, for whom he wrote 85 songs. Most of his compositions were written with lyricist partners Johnny Burke and Sammy Cahn. His string of hits began in 1939 with "Darn That Dream" and continued through the 1970's. “Come Fly with Us” is one of the many events going on across the country in celebration of this great composer. It is sponsored by Van Heusen Music, the Frist Foundation and Lipscomb University. Representatives from Van Heusen music, including members of the composer's family, will be present for this historic event. The Nashville Jazz Workshop provides the community with quality jazz education through workshops where jazz professionals pass on their knowledge & experience in a journeyman/apprentice situation, classes for players and non-players and performances to promote community appreciation of jazz.import { getActiveDomain, getMainCarrier, Hub } from '@sentry/hub'; import { CustomSamplingContext, SamplingContext, TransactionContext } from '@sentry/types'; import { dynamicRequire, extractNodeRequestData, getGlobalObject, isInstanceOf, isNodeEnv, logger, } from '@sentry/utils'; import { registerErrorInstrumentation } from './errors'; import { IdleTransaction } from './idletransaction'; import { Transaction } from './transaction'; import { hasTracingEnabled } from './utils'; /** Returns all trace headers that are currently on the top scope. */ function traceHeaders(this: Hub): { [key: string]: string } { const scope = this.getScope(); if (scope) { const span = scope.getSpan(); if (span) { return { 'sentry-trace': span.toTraceparent(), }; } } return {}; } /** * Implements sampling inheritance and falls back to user-provided static rate if no parent decision is available. * * @param parentSampled: The parent transaction's sampling decision, if any. * @param givenRate: The rate to use if no parental decision is available. * * @returns The parent's sampling decision (if one exists), or the provided static rate */ function _inheritOrUseGivenRate(parentSampled: boolean | undefined, givenRate: unknown): boolean | unknown { return parentSampled !== undefined ? parentSampled : givenRate; } /** * Makes a sampling decision for the given transaction and stores it on the transaction. * * Called every time a transaction is created. Only transactions which emerge with a `sampled` value of `true` will be * sent to Sentry. * * @param hub: The hub off of which to read config options * @param transaction: The transaction needing a sampling decision * @param samplingContext: Default and user-provided data which may be used to help make the decision * * @returns The given transaction with its `sampled` value set */ function sample<T extends Transaction>(hub: Hub, transaction: T, samplingContext: SamplingContext): T { const client = hub.getClient(); const options = (client && client.getOptions()) || {}; // nothing to do if there's no client or if tracing is disabled if (!client || !hasTracingEnabled(options)) { transaction.sampled = false; return transaction; } // we would have bailed already if neither `tracesSampler` nor `tracesSampleRate` were defined, so one of these should // work; prefer the hook if so const sampleRate = typeof options.tracesSampler === 'function' ? options.tracesSampler(samplingContext) : _inheritOrUseGivenRate(samplingContext.parentSampled, options.tracesSampleRate); // Since this is coming from the user (or from a function provided by the user), who knows what we might get. (The // only valid values are booleans or numbers between 0 and 1.) if (!isValidSampleRate(sampleRate)) { logger.warn(`[Tracing] Discarding transaction because of invalid sample rate.`); transaction.sampled = false; return transaction; } // if the function returned 0 (or false), or if `
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appear never to have been printed. The Wisbech Players was founded in 1954 through the amicable break up of the Wisbech Little Theatre drama group run by Mrs Sheila Chesters, who was also busy running this successful children's choir competing at King's Lynn Festival, Albert Hall, Edinburgh and Aldeburgh. The society's production of A Hundred Years Old, by S & J Quintero took place at the Women's Institute Hall (since 2009 The Luxe Cinema). Two productions per year were put on most years once the society was established. This was eventually reduced to one. The productions at the turn of the century were Arsenic and Old Lace by Joseph Kesselring and 'Allo 'Allo based on the tv series by Jeremy Lloyd and David Croft. 21st century For the fiftieth anniversary in 2004, Joan Littlewood's Oh! What a Lovely War was put on at the Georgian Angles Theatre. The society returned to two productions in 2007 with Rebecca (play) and Steel Magnolias (play). Far from the Madding Crowd by Thomas Hardy and adapted by playwright Jessica Swale was the 2018 spring play. In 2019 Ladies in Lavender directed by Barbara Mews and adapted for the stage by Shaun McKenna was the Spring production performed at the Angles. The spring 2019 production was Cheshire Cats by Gail Young, which raised £285 for the Breast Care Unit at The Queen Elizabeth Hospital, King's Lynn, followed by the autumn production of A Bunch of Amateurs, written by Ian Hislop and Nick Newman for a cast of seven. The spring 2020 productions is The Innocents by William Archibald to be staged at The Angles. References Category:Amateur theatre companies in England1-I bet Brett Favre drinks Night Train or Mad Dog over Thunderbird. 2-karma probably would have to make the kid a Viking or Bear fan. and that'd raise more questions about whether the kid was mine than if he/she came out black. 3-regarding the leave of absence, yeah, i'm all but retired from NFLDC now, in case ya haven't noticed. but, i'll post when i can. I got a better job within my company, and now i'm expected to, ya know...work at work. 1-I bet Brett Favre drinks Night Train or Mad Dog over Thunderbird. 2-karma probably would have to make the kid a Viking or Bear fan. and that'd raise more questions about whether the kid was mine than if he/she came out black. 3-regarding the leave of absence, yeah, i'm all but retired from NFLDC now, in case ya haven't noticed. but, i'll post when i can. I got a better job within my company, and now i'm expected to, ya know...work at work. oh yeah, and thanks for all the congrats....i'm pretty pumped. I'll always remember you as the guy with the Tool av. And, you know, the guy that knocked up his wife. But mostly the Tool av...Swansea Market Swansea Market situated in the heart of Swansea city centre is the largest indoor market in Wales. The market is covered by a steel arched portal frame roof clad in steel and glass. The current market was built in 1959-1960 by Percy Edwards. Adjoining the market is the Quadrant Shopping Centre. History The current market building is the fourth market to be built at the site in 200 years. The site has been used as a market since the Middle Ages. The previous market on this site had existed since 1894 and was destroyed during bombing raids during World War II. The first dedicated market building on the site was built in 1774 consisting of a roof supported by pillars. It had no external walls. A new market called the New Market was opened in 1830 which was a walled structure with a roof lining the walls. The interior market space was open to the elements. The open walled structure was replaced with a new red brick building which opened in July 1897. The new building was entirely roofed and by December 1897, electric lighting had been introduced. This building was hit during the Luftwaffe bombing raids in 1941 destroying the roof and the interior of the building. During the rest of the 1940s and 1950s, the market was held as an outdoor market at site where the market building once stood. The replacement market opened in 1961, celebrating its 50th anniversary in 2011. Facilities The market includes fruit and vegetable stalls, butchers, cafes, fast food, fishmongers and clothes stalls. There are also a number of stalls selling local and continental delicacies, such as continental cheeses, Welsh laverbread, Penclawdd cockles, Gower Saltmarsh lamb and Welsh Black beef. In 2013 the market roof was due for a £1 million modernisation consisting of new roofing sheets and lighting and possibly new solar power generating roofing panels. References External links Swansea Market (official site) SwanseaHeritage.net Swansea Market Category:Buildings and structures in Swansea Category:Retail markets in Wales Category:Shopping in Swansea Category:Buildings and structures completed in 1960 Category:Food markets in the United KingdomMonday, June 21, 2010 Rule of threes Wednesday, April 7, 2010 The Rule of Threes It happened again. I ran out of propane....on Easter! The turkey was in the wood cook stove, so that was not a big deal, but I had wanted to put the extra stuffing and rolls in the propane oven. I lit the oven and then - poof- the flame blew out! AARG. But in reality, being out of propane is nothing more than a slight inconvenience. You see, we try to operate on "The Rule of Threes". We attempt to have three ways to do just about anything. We have a back-up for our back-up! We have a propane cook stove, but also an electric tea kettle and microwave, and of course, the wood cook stove. We can cook three different ways. If one doesn't work, we have a back-up. Say we don't have enough battery power to run the electric kettle - we just pop the kettle on the gas stove. Out of gas too? Not a big deal, there is the wood stove. The Hobbes Electric Kettle... On the Propane Stove.... And the ever present Wood Cook Stove.... We try to employ the Rule of Threes in other areas of our lives as well, with varying degrees of success. Our power system is only operating on the Rule of Two. We have solar panels and a generator back-up. We did have a wind turbine, but one of the guy wires broke so we took it down. The turbine only put out about 17 amps max, and in heavy wind, put the brakes on and produced nothing. We would like to replace it with a much larger turbine and also build a battery booster. I guess that would be The Rule of Fours! Talk about a feeling of security. If one system fails, there is always another way. I am constantly looking at ways to improve all of your systems, be they food storage, laundry or organizing our days. But the one true constant is The Rule of Threes. FeedBurner FeedCount Follow by Email Search This Blog Paratus Familia Resources About Me I am a christian, conservative, survival minded, homeschooling,off-grid, independent, home-birthing, Proverbs 31, Titus 2 minded 40 year old woman. I live with my husband and five children in our solar/generator powered shop on 30 acres. We are homestead types who try to do as much as we can ourselves, but understand the importance of community.[A Case of Squamous Cell Carcinoma of the Breast]. A 67-year-old woman presented with a 3 cm palpable mass in the lower lateral quadrant of her right breast. Mammography and ultrasonography showed a mass with an irregular border. Using fine needle aspiration biopsy and cytology, we detected malignant cells with keratosis, and made a diagnosis of squamous cell carcinoma(SCC). We performed total mastectomy with axillary lymph node dissection. Histologically, the tumor was identified as SCC with keratinization and a component of scirrhous adenocarcinoma; estrogen and progesterone receptor expression were not elevated. The tumor tested negative for HER2. The patient did not receive any adjuvant chemotherapy and is alive with no recurrence 13 years after surgery.Best AWD Cars Under $30,000 It’s a very simple fact, the best AWD cars under $30,000 are some of the best cars on the road in any class. It’s a rare animal indeed that can combine the traction of all-wheel drive with spaciousness, comfort and reliability, all for under $30K. These are the cars that are best suited to just about any driver. They’re great for families or for singles who are just looking for a sporty, stylish vehicle with tremendous handling and all-weather traction. They’re safe, they’re reliable, and they’re affordable. Do yourself a favor and get out there and test drive one of the best AWD cars under $30,000.
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prediction agrees very well with the data given in Ref. [@Roisman2018] for water. Comparing to our contact times of ethanol drops, Fig. \[fig:ContactTimes\_SapphSi\](a), no range of (even roughly) constant $t_c$ for $T_s<200^{\circ}C$ exists, in [*qualitative*]{} disagreement to Ref. [@Roisman2018]. One might at first assume that this may be due to changing material parameters with increasing temperature, but this is not the case: Inserting the temperature-dependent thermal diffusivity and kinematic viscosity of ethanol into Eqn. (\[eq:tc\_Roisman2018\]), based on the thermal conductivity $k$ calculation from Assael et al. [@Assael2013] and the other temperature-dependent material parameters given in the DDBST Dortmund data base (e.g. Refs. [@EthDynViscosity; @EthDensity]), and using $b=1.0$, we obtain contact times $t_c$ between $7.5$ and $7 ~\rm ms$ with a decreasing trend in the range between $T_s=165^{\circ}$C and $200^{\circ}$C. This order of magnitude is agreeable below $180^{\circ}$C, and changing $b$ does not change the qualitative trend. Again, the method of contact time determination may play an additional role: Our measured optimal lift-off times of $t_{l,\rm min}\approx~\rm 8~\rm ms$, Fig. \[fig:ContactTimes\_SapphSi\](c), agree well with Roisman’s estimation providing the time of lamella rupture. After rupture, the lamella retraction is expected to occur analogue to the rupture of low-viscosity liquid films presented by Taylor [@Taylor1959] and Culick [@Culick1960], see also Ref. [@Villermaux2007].\ Let us now analyze the duration that the drops reside in vicinity of the substrate, the lift-off times $t_l$, Fig. \[fig:ContactTimes\_SapphSi\](b)–(d). At first glance, again the data on silicon and sapphire are similar and agree within the standard deviation of the data sets at given substrate temperature $T_s$. Contact and lift-off times in Regime I are on the order of few a seconds (not shown in the plot). Thus, the better thermal conductivity of silicon compared to sapphire has only small influence on the contact and lift-off times here. For impact on silicon (black squares, in (b) and (d)), we observe an initial slight decrease of the lift-off time below $T_s=180^{\circ}$C, and an almost constant lift-off time for $180^{\circ}$C $\leq T_s\leq 240^{\circ}$C. Above $T_s=240^{\circ}$C, $t_l$ slightly increases, followed by a slight decrease toward higher temperatures in the Leidenfrost Regime IV, continuing until $T_s=550^{\circ}$C, where $t_l\approx 11.6~\rm ms$. This slow decrease at high temperatures can be expected given that the vapor layer separating drop and substrate grows in thickness [@Lee2018a]. Thus, the small friction in the vapor layer decreases with increasing temperature, an one may presupposes that less surface energy is dissipated. Between $T_s=165^{\circ}$C and $240^{\circ}$C, $t_{l,\rm Si}$ is roughly constant between $16~\rm ms$ and $18~\rm ms$. This experimentally determined rebound time agrees with the expectation from literature: There, it is approximated by the period of an oscillating drop [@Makino1984] as $t_l \approx \pi/4\sqrt{\rho_0 D_D^3/\gamma} = 13.3~\rm ms$, using the material properties at room temperature. Slightly larger empirical pre-factors than $\pi/4$ were given by Biance et al. [@Biance2006] (prefactor 0.937, $t_l\approx 15.8~\rm ms$) and Chen et al. [@Chen2007] (prefactor 1.12, $t_l\approx 18.9~\rm ms$). The lift-off times on the sapphire substrates display a shallow local minimum between $T_s=170^{\circ}$C and $180^{\circ}$C, where the mean lift-off time reduces to only $t_{l,~\rm Sa}\approx 13.3~\rm ms$, before it rises again for higher temperatures to $16~\rm ms$ and $18~\rm ms$ (the same value as measured on Si). In the enlarged plot of Fig. \[fig:ContactTimes\_SapphSi\](c), we added the values in the individual measurements. One observes that numerous points center around $\approx 10~\rm ms$, whereas measurements with much higher lift-off times, occur at the same substrate temperature. More details and the mechanism behind this substantial lift-off time reduction are provided in Sec. \[Sec:Holes\].\ Last, let us sketch the general time evolution of the contact characteristics of a drop impacting on a hot plate in terms of Fig. \[fig:ContactLift-off\_ColorGraphs\]: Time evolves along the ordinate axis. The colored regions in the plots correspond to certain contact behavior: the blue region denotes contact with the substrate. In the red regions, the droplet is close to the substrate but contact-less (e.g. a Leidenfrost drop during spreading and receding), and the yellow region corresponds to times when the drop has accomplished its first lift-off or rebound. At low temperatures, the lift-off velocity is small and the re-approach of the droplet to the substrate occurs after very short time. An ethanol drop impacting on a substrate at $T_s=150^{\circ}$C will remain in contact (blue region) all the time until it fully decomposed or evaporated (Regime I). At slightly higher temperature, $t_c=t_l$ (Regime II), i.e. the drop is initially attached to the substrate, but finally lifts off the substrate (direct transition from the blue to the yellow region). The width of this temperature range is only around 10 K (cf. also Fig. \[fig:StateDiagram\]). For a broad range of temperatures, the contact is lost prior to lift-off or rebound (Regime III, range $170^{\circ}$C$\leq T_s\leq 250^{\circ}$C on sapphire). This refers to a first cross-over from blue to orange, and then to the yellow region. Finally, in the Leidenfrost regime IV, drops spread and recede close to the substrate without any contact, before they rebound (transition red to yellow). Droplet Dynamics near the Minimum Lift-off Time {#Sec:Holes} =============================================== ![Statistics of lift-off times in Regime II: Cumulative probability distributions of the lift-off time and mean lift-off times in dependence of the initial substrate temperature. The minimum occurs around $173\dots 175^{\circ}$C (green and orange curves, triangles), with average $t_{l,~\rm min}\approx13.3~\rm ms$. The probability distributions below these temperatures possess 2 peaks, one at low, and one at high temperatures, seen by the drastic change of slope in the blue curves (b). Marked points in (a) correspond to image sequences in Fig. \[fig:minimum\_imageSeq\]. Ethanol drops of $D_D=2~\rm mm$ diameter impacting at velocity $1~\rm m/s$ on the sapphire substrate, measurements from side view imaging.[]{data-label="fig:minimum_statistics"}](TProbabilities_zus_anno_s.png){width="\columnwidth"} ![Hole formation and sticking govern the lift-off, exemplary tilted top view image sequences corresponding to the marked points in Fig. \[fig:minimum\_statistics\](A): White arrows indicate early formed holes. (a) Lamella rupture with insufficiently fast retraction of the contact underneath the central drop region, central droplet is stuck, practically no lift-off. (B) optimal situations: hole expansion and sufficiently fast retraction of the contact (see also Fig. \[fig:minimum\_TIR\]), lift-off in shape of a disintegrated pancake. (C) Increased temperature with rebound of a single drop, Regime III, heat transfer during spreading is insufficient to cause lamella rupture, $t_c \ll t_l$. The arrows in (A) and (B) indicate the first hole formed in the lamella. Numbers give the time after impact (identified in TIR) in milliseconds. Maximum spreading is reached after $\approx 6.35~\rm ms$. Ethanol drops of $D_D=2~\rm mm$ diameter impacting at velocity $1~\rm m/s$ on the sapphire substrate. \[fig:minimum\_imageSeq\]](070519_HolesSticking_All1.png){width="\columnwidth"} ![Contact, hole formation and spreading dynamics for a drop with small lift-off time in the minimum region in Regime II, see Fig. \[fig:minimum\_imageSeq\](b): Ethanol drop of $D_D=2~\rm mm$, $U_0=1~\rm m/s$, impacting on a sapphire substrate at initial temperature $T_{\rm
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personas esperándome sentadas en la mesa de una cocina. En esos casos tenía que tranquilizar a los anfitriones, asegurarles que no había problema en que fuéramos pocos y felicitarles por el refrigerio con el que nos agasajaban. Otras veces asistía a un servicio religioso entero y el pastor se olvidaba de mencionarme o el líder del sindicato local me daba la palabra justo antes de anunciar que el sindicato había decidido dar su apoyo a algún otro candidato. Pero estuviera con dos personas o con cincuenta, estuviera cómodamente a la sombra en una de las señoriales mansiones de la orilla norte de Chicago, en un apartamento sin ascensor del lado oeste de Chicago o en una granja cerca de la ciudad de Bloomington, fuera la gente amable, indiferente o —en pocas ocasiones— hostil, me esforcé por mantener la boca cerrada y aplicarme en escuchar lo que tenían para decirme. Me hablaron de sus trabajos, de sus empresas, de las escuelas locales; de lo enfadados que estaban con Bush y también con los demócratas; de sus perros, de su dolor de espalda, de sus experiencias en la guerra y de las cosas que recordaban de su infancia. Algunos tenían teorías muy completas para explicar la pérdida de trabajos en el sector industrial o el alto costo de los cuidados de salud. Algunos repetían lo que habían oído decir en el programa de Rush Limbaugh, el popular locutor de radio conservador, o en NPR, la cadena nacional de radio pública. Pero la mayoría estaban demasiado ocupados con sus trabajos o sus hijos para prestar atención a la política y hablaban de lo que habían visto con sus propios ojos: una fábrica que cerraba, un ascenso, una factura de calefacción altísima, su padre en una residencia para ancianos, o los primeros pasos de su hijo. De aquellos meses de conversaciones no surgió ninguna epifanía deslumbrante. Si acaso, lo que me sorprendió es lo modestas que eran las esperanzas de la gente y lo mucho que tenían en común independientemente de su raza, procedencia, religión y clase social. La mayoría creía que cualquiera que estuviera dispuesto a trabajar debería poder encontrar un trabajo con el cual ganarse la vida. Pensaban que la gente no debería tener que declararse en bancarrota por el sólo hecho de enfermarse. Pensaban que todos los niños tenían derecho a recibir una buena educación —que eso no debía quedarse sólo en palabras vanas— y que esos mismos niños debían poder ir a la universidad aunque sus padres no fueran ricos. Querían sentirse seguros, a salvo tanto de delincuentes como de terroristas; querían aire limpio, agua limpia y poder pasar tiempo con sus hijos. Cuando fueran ancianos querían poder jubilarse con dignidad y respeto. Y básicamente, eso era todo. No era pedir demasiado. Y aunque comprendían que les iba a ir bien o mal en la vida según se esforzasen más o menos; aunque no esperaban que el gobierno resolviese todos sus problemas y aunque, desde luego, no querían que se malgastase el dinero de sus impuestos, creían que el gobierno tenía que poder ayudarles. Les dije que tenían razón: el gobierno no podía resolver todos sus problemas. Pero que cambiando simplemente un poco nuestras prioridades, podríamos garantizar que todos los niños tuvieran la oportunidad de salir adelante en la vida y mejorar nuestra posición ante los desafíos a los que nos enfrentamos como nación. La mayoría de las veces la gente asentía con la cabeza y preguntaban qué podían hacer ellos para ayudar. Y cuando acababa la reunión y me encontraba otra vez en la carretera, con un mapa abierto sobre el asiento del pasajero, de camino a la siguiente cita, una vez más recordaba por qué había decidido ser político. Sentía ganas de trabajar más duro de lo que jamás había trabajado en toda mi vida. ESTE LIBRO es el producto de todas aquellas conversaciones que mantuve durante la campaña. Mis encuentros con los votantes no sólo me confirmaron que el pueblo americano es fundamentalmente decente y honesto, sino que también me recordaron que al centro de la experiencia americana existen una serie de ideales que siguen tocando nuestra conciencia colectiva. Son un conjunto de valores comunes que nos unen a pesar de todas nuestras diferencias; un hilo continuo de esperanza que hace funcionar este improbable experimento que llamamos democracia. Esos valores e ideales no sólo se encuentran en las losas de mármol de los monumentos o en los relatos de los libros de historia. Siguen vivos en las mentes y los corazones de la mayoría de los americanos y hacen que nos sintamos orgullosos, cumplamos con nuestro deber y, si es necesario, aceptemos sacrificios. Sé que es arriesgado hablar así. En esta era de globalización y vertiginosos cambios tecnológicos, de política encarnizada e incesantes guerras culturales, parece que ya ni tan siquiera tenemos un lenguaje común con el cual podamos discutir nuestros ideales y mucho menos las herramientas necesarias para alcanzar un consenso general sobre cómo trabajar juntos, como nación, para hacer realidad aquellos ideales. La mayoría de nosotros somos conscientes de los misterios de la publicidad, las encuestas, los redactores de discursos y los analistas políticos. Sabemos que las grandes palabras pueden utilizarse para objetivos cínicos y el poder, la necesidad, la avaricia o la intolerancia pueden subvertir hasta los sentimientos más nobles. Incluso los manuales de historia más sencillos muestran hasta qué punto, desde su misma concepción, la realidad de la vida en los Estados Unidos ha diferido de sus mitos. En este clima, cualquier afirmación de ideales compartidos o de valores comunes, parece extremadamente ingenua, cuando no directamente peligrosa. Puede parecer un intento de encubrir diferencias importantes respecto a políticas o actuaciones o, peor aún, un medio de callar a quienes creen que nuestras instituciones actuales no les ofrecen nada. Mi postura, no obstante, es que no tenemos opción. No hace falta ninguna encuesta para saber que la inmensa mayoría de los americanos —sean republicanos, demócratas o independientes— están hartos de la zona muerta en la que se ha convertido la política, en la que intereses que representan a muy pocos tratan de conseguir ventajas y las minorías ideológicas intentan imponer su particular versión de la verdad. Seamos de estados rojos o azules, sentimos en nuestras entrañas la falta de honestidad, rigor y sentido común del debate político y nos disgusta lo que parece una retahíla continua de alternativas falsas o idénticas. Religiosos o laicos, negros, blancos o latinos, sentimos —y con razón— que no se atiende a los desafíos más importantes de la nación y que si no cambiamos de rumbo pronto, puede que seamos la primera generación en mucho tiempo que deje a sus hijos un país más débil y dividido que el que heredó de sus padres. Quizá más que en ningún otro momento de nuestra historia reciente, necesitamos una nueva forma de hacer política, que sea capaz de basarse y construir sobre lo que nos une como americanos. De eso se trata este libro: de cómo iniciar el cambio de nuestra política y nuest
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Tom insisted, running after her. "Saw what?" she asked, turning round to face him. He stared at her in disbelief. "Light coming out of your hands. Shane Biggs flying through the air. Does any of this sound familiar? How did you do it?" Stella tried to laugh sarcastically, but it sounded weak even to her. "I don't know what you mean. If this is a joke, it's not very funny." She strode past him and into school. The corridors were still busy, with people going to class. _"Joke?_ I know what happened, Stella. I saw it," Tom shouted. His voice was loud enough to be noticed, and Stella cringed at the looks they were getting. She realised that the whole of her year were waiting for a class in the hallway, and all of them were looking at them with curiosity. She walked back to Tom and grabbed hold of the front of his jumper. "I don't know what you think you saw. But just forget it, right?" she hissed to him. "Look, it's Smella Mayweather and that cry baby Warner. What's the matter, having a lovers tiff?" somebody shouted. Stella swiveled her head around to find herself face to face with Shane Biggs. His hair had been cut really short, although there were still places where you could see that it was singed. When he realised how close he was to Stella, he went pale and took a step back, but then he recovered, and his lips curled into a sneer. "Go on, Smella, make up with your _boyfriend_." There was a lot of giggling in the corridor, and she heard somebody from her class whisper loudly to her friend, "A match made in heaven, the cry baby and the freak." Stella felt her face flush red. She quickly let go her grip on Tom's jumper, causing him to stagger forward. He stretched out his arms and grabbed hold of Stella for balance. The giggling in the corridor got louder, and somebody called out, "Ah, isn't that sweet. They're having a cuddle." Desperately, Stella pushed Tom upright. "Just keep away from me, Tom. Keep away!" *** Chapter 3: Followed After the display in the corridor, things did not go well for Stella at school. Everybody seemed to think that Stella and Tom were boyfriend and girlfriend. She was constantly being teased in class by people making kissey noises at her. She soon got sick of saying that she and Tom weren't together and tried to ignore all the comments. Tom wasn't helping: he just wouldn't stay away from her. If it wasn't for the look of terror on his face whenever he got within ten yards of her, Stella could have believed that Tom _did_ actually like her. Wherever she was in the school, he always seemed to be around the corner. Despite trying to warn him away with a frosty look or snarling at him to, " _Go away_ ," every lunchtime in the canteen, he'd always have an empty chair next to him. She'd stalk straight past him, but he would cause a lot of sniggering by calling out for her to sit with him. She even suspected that he was following her home. A glimpse of movement would often catch her eye, but whenever she stopped and span around, nobody appeared to be there. What disturbed Stella the most, though, was that whenever she saw Tom, she was reminded of what had happened to Shane Biggs. One evening, Stella was in her room, trying to do some homework. She couldn't keep her mind on the pages of her exercise books. The same thoughts spun around her head, like clothes in a washing machine, ' _Did I blast Shane Biggs into the tree? How did I do it? What if it happens again?_ ' Tom had said something about light coming out of her hands. Stella stretched out her arms and carefully examined her palms and fingers. They looked the same as they had always done. Cautiously, she pointed her hands at her homework and shouted, "STOP!" Her book was unharmed. The only marks on it were her handwriting. She remembered that she had been really angry before and there had been that strange rushing sound. Stella tried to build up a rage over the stupid maths questions that she was meant to be doing. "STOP!" she yelled again, this time with more force. "Stella! Stop making that racket!" Her mum's voice floated up to her. Stella looked down. Her homework had stubbornly remained unsinged. She gave a sigh and slumped onto her bed. In spite of everything, she felt a bit disappointed, "Maybe it was just a fluke," she said to herself. "Maybe I didn't do anything at all." She was interrupted from these disturbing thoughts by the wet sound of chewing coming from under the bed. "Helix," Stella called out, "you haven't got in the fridge again?" She sometimes regretted that she'd taught Helix how to stand on his hind legs and use his nose to open the fridge door (she knew that her mum definitely regretted it). Stella peered under the bed, expecting to see some leftover chicken being licked clean by a hungry husky. It seemed, however, that Helix had found himself a dog toy. "What is that?" Stella asked. She reached under the bed and tried to pull the object that Helix was chewing out of his mouth. Helix was unwilling to give it up without a fight and clung on with his jaws until Stella managed to yank it away from him. "Yuck! You've slobbered all over it." The toy felt like it was made of thick jelly. It was wet because of being in Helix's mouth and surprisingly warm to the touch. Helix's teeth marks were gradually smoothing away, and it was regaining its shape after being stretched by their tug of war. It was bright orange and shaped like a man, with arms, legs, torso and a round head. The small face had eyes and a nose, but no mouth. "Where did you get this, Helix?" Dogs don't shrug as a rule, but Helix did a good impression. "I suppose Mum must've got it for you. You best look after it. You know how she's always threatening to shave you if you keep breaking things." Helix gave an offended sniff. He always claimed that it was Stella's dad that broke things and felt it was pretty mean that they always blamed the dog. *** The next morning, Stella grabbed her school bag from her room as usual, but didn't notice that the orange figure was inside until she pulled out her maths book in class and she found it fixed onto the front cover. It was stuck face down, arms and legs stretched out like a starfish. Her maths teacher was called Mrs Jenkins, and it was an unfortunate fact that her face had an unhappy knack of turning a bright puce whenever she got upset. She was painfully aware that some classes would deliberately wind her up just to see the brilliant flush of pink stretch up to her hair. It was because of this that she was always on the lookout for bad behaviour. "No toys in class, Stella Mayweather. You know the rules. Put it away," Mrs Jenkins told Stella, once she had noticed Helix's dog toy. "Yes, Miss," Stella replied, trying to prize the jellied man off her book. For some reason it was stuck fast. Her struggle started a ripple of laughter through the class, and Mrs Jenkins's face started to glow pink. "I said put it away!" Mrs Jenkins reached over and tried to peel the toy off the book. There was a loud rip as the book cover tore away. She held the little orange man in the air as the cardboard cover suddenly came unstuck and fluttered to the floor. There was another burst of laughter from the class. "That is school property," Mrs Jenkins squeaked, her face almost purple now. "Detention for you, girl, and I'm confiscating this – this thing." But the orange man had stuck itself to Mrs Jenkins's hand, and she frantically shook her arm to try and unloose it. With a mighty heave, the toy was thrown from her hand and sailed through the air like an orange snowball, landing with a splat on Mrs Jenkins's whiteboard. It stuck there throughout the rest of the lesson, its gum-like eyes staring into the distance. A flustered Mrs Jenkins told the class to copy out times tables in silence, whilst she fanned her face back to a rosy pink with the cover of Stella's maths book. Stella was late getting out of school because of her detention, and Helix complained of the wait because the ice on the pavement had made his paws cold. "It's your fault for putting your toy in my bag," she told him. Helix denied putting anything in her bag, and they both were moody with each other all the way home. It didn't help Stella's grumpiness that she was sure that Tom was following her again. She tried darting into doorways and peering behind her, but couldn't actually
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IPCC), has recognized that when local communities’ land rights are jeopardized, it poses risks to both people and the planet. “We have cared for our lands and forests — and the biodiversity they contain — for generations. With the right support we can continue to do so for generations to come,” reads a statement from indigenous and community organizations from 42 countries spanning 76 percent of the world’s tropical forest in response to a report from the IPCC. A study published this week in the journal PNAS found that the most effective way to protect the Amazon rainforest might be to leave it in the hands of its indigenous residents. The Amazon now releases more carbon dioxide than it stores, in large part due to forest loss from mining, logging, agriculture, and fires. The study also looked at regions that were best able to stop that from happening, and found that indigenous territories had the best success rates. Between 2003 and 2016, lands under indigenous control had the smallest losses of carbon because the forest stayed intact and regrew in places that had been disturbed. The study also warned that the ability of indigenous peoples to protect their lands is under threat. Brazilian president Jair Bolsonaro has been accused of encouraging the genocide of indigenous tribes at the same time that he’s pledged to open up more parts of the Amazon for development. The lead author of that study, however, cautions against pitting all tree planting efforts against forest conservation. “It’s not like these two things are in competition,” says Wayne Walker, a scientist at the Woods Hole Research Center. Maintaining existing forests should be a priority, but restoring trees to places where they’ve been lost can sometimes be the next best option, he says. not all tree-planting initiatives are created equal Still, not all tree-planting initiatives are created equal. The location, species planted, and how people are involved can all jeopardize success. In India, leading environmental groups opposed a project to plant 2 billion trees in the Cauvery river basin supported by the Leonardo DiCaprio Foundation. They claimed in a letter that the campaign threatened to dry up streams and destroy habitats. People who live alongside and depend on the river would be affected too, says Prakash Kashwan, a political science professor at the University of Connecticut. Problems may be complex, solutions can be simple. The Champions for #1TrillionTrees Platform will change the ecological trajectory of our planet, combat #ClimateChange – a crucial step in the right direction. Let’s make it happen. -Sg #WEF20 @1t_org https://t.co/gNyMtRVhwv pic.twitter.com/G11a56tT0q — Sadhguru (@SadhguruJV) January 22, 2020 Organizers of the Cauvery tree-planting project have said the criticism against it is “a baseless opinion that contains blatant untruths and loose comments with no backing in facts.” It says the trees will revive the river by increasing water retention. The founder of the foundation that launched it, yogi and author Sadhguru, joined Salesforce’s Benioff at a press conference for the trillion trees campaign in Davos. That global initiative could help his project “scale this up to 50 to 60 billion trees across the country,” Sadhguru said on the panel. That worries Kashwan. The buzz generated by big international campaigns can give prestige to projects that have been rejected on the ground. “They get new lives because you know, the World Economic Forum is talking about it,” he says.Mating type genes in the genus Neofusicoccum: Mating strategies and usefulness in species delimitation. The genus Neofusicoccum includes species with wide geographical and plant host distribution, some of them of economic importance. The genus currently comprises 27 species that are difficult to identify based on morphological features alone. Thus, species differentiation is based on phylogenetic species recognition using multigene genealogies. In this study, we characterised the mating type genes of Neofusicoccum species. Specific primers were designed to amplify and sequence MAT genes in several species and a PCR-based mating type diagnostic assay was developed. Homothallism was the predominant mating strategy among the species tested. Furthermore, the potential of mating type gene sequences for species delimitation was evaluated. Phylogenetic analyses were performed on both MAT genes and compared with multigene genealogies using sequences of the ribosomal internal transcribed spacer region, translation elongation factor 1-alpha and beta-tubulin. Phylogenies based on mating type genes could discriminate between the species analysed and are in concordance with the results obtained with the more conventional multilocus phylogenetic analysis approach. Thus, MAT genes represent a powerful tool to delimit cryptic species in the genus Neofusicoccum.Donald Driver With Driver having a quad injury, 2 offseason surgeries, and no catches the past two weeks are we looking towards the end of drivers career? I know he signed an extension, but at this point I wonder if its counter productive to have him on the field instead of one of our younger WRs? We know Rodgers needs all the time he can with these young WRs to develop a connection. oooooooo I just read this.. DD IS what Packers mean to me!!! He's always been such a great player,... I know every great player must bow out at some point... (ahem*)...but I really don't think its Donald's time yet!!!! Nooo not yet! I don't know, I mean, he's such a comfort to have out there on the field. He can consistently catch the ball, maybe his age just means being injured more often. Without the injuries, he's looked the same as he always has. Sounds like that quad has been nagging him for, what, about 3 weeks now? I think it started in the Miami game this year. I definately don't think that this is the beginning of the end of DD. But I do think that it is the beginning of the end of DD running those dangerous short slants across the middle. He is in such awesome physical shape, I don't think that a quad problem i going to keep him in active for long, certainly not career threatening. I also like the two weeks of rest theory. Cowboys secondary is b.a.d. It might be nice to see GJ have a monster day. With Finely and DD gone, and obviously a non-threatening rushing attack, lets see our offense really center around one of the best receivers in the league-GJ85. Don't be to hasty guys. He has had a quad injury. It most likely wont be a season ending injury. It's like a pulled hamstring except it's with the quad. What's this I hear about DD not having enough in the tank and not making the roster next year. He was doing fine before the quad injury. If u take away the last 2 games he had 307 yards in 5 games. Not flashy numbers but it's still productivity considering we like to spread the ball around. Put it this way you will see DD in a packer uniform at least 2 years from now. You can take that to the bank. We all know Driver will drop off ... hopefully he's got a little left in the tank though. The unsettling thing for me is the guys behind him (especially Jones) do not look like they will be able to pick up the slack. Jordy had a nice game today, but Jones has regressed. Poor game against Miami and a poor game today. He needs to make the catch on the long ball and also made a bad read when he cut off his route. After all the preseason hype, Jones looks pedestrian at best. He lacks top end speed, is a bit fumble prone, and now is dropping passes he should catch. I wonder how confident Rodgers is in his play right now. Click to expand... You must have missed Jones big game against Minn. It was a pretty good game. I dont know why everyone is so quick to say someone is done so fast. Before DD got hurt he was on track for 1000yds or really close. Let him heal up and he will be back. Click to expand... He would have been on pace for 800 yards. No one is saying he is "done" but more of is it heading towards that. And why? Well the multiple injuries and the absence from games lately. 2 ankle surgeries in the offseason is pretty serious for a wr, especially a 35 year old one that has made a career running across the middle. I would love as much as anyone to get another 5 years out of him but I am wondering if that is in the teams best interest with young WRs waiting in the wings? NOOO! this is so crazy, im laying in bed thinkin about todays game and i start thinking "dang we have such a good team, i wonder how much longer DD is gonna play..." So I come here to make a post and BAM! theres one riiiight here lol. We all love DD one of GB all time best receivers, a good guy. I think that he has maybe a couple seasons in em'. He comes up with big plays and is probably teaching the young recievers ALOT. I dont know about yall but i think come playoffs hes going to be valuable. Although he is going to eventually leave us, I think he has some more work to do before he goes. *SB cough cough SB* No one is saying he is "done" but more of is it heading towards that. And why? Well the multiple injuries and the absence from games lately
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. 6.. Powering the apicoplast: addressing sources of reducing power and atp {#s6} ========================================================================= Like all plastids, the apicoplast needs ATP and reducing equivalents to power its metabolic pathways like FASII. In the absence of photosynthesis and any plastidic ATP/ADP transporter, the apicoplast has to generate ATP somehow. In the malaria parasite, the conversion of imported PEP to pyruvate for the FASII or DOXP pathway seems to be the sole source of ATP for the apicoplast ([@RSTB20090273C56]). The reaction is catalysed by the plastidic pyruvate kinase (pPK), which is phylogenetically distinct from cytosolic pyruvate kinases and is demonstrated to be an apicoplast-resident enzyme (pPK; L. Lim, N. J. Patron & G. I. McFadden, unpublished data; [@RSTB20090273C116]; [@RSTB20090273C35]). To cope with some of the demands for reductants in the apicoplast, the organelle harbours a plant-type ferredoxin-NADP^+^ reductase (FNR)/ferredoxin (Fd) redox system, which works in a manner similar to the non-photosynthetic FNR/Fd systems ([@RSTB20090273C115]; [@RSTB20090273C63]). In photosynthetic plastids, Fd receives electrons from photosystem I and the reduced Fd, in turn, is used by FNR to produce NADPH from NADP^+^ for the Calvin cycle. In non-photosynthetic plastids, the ferredoxin redox system operates in the reverse direction. FNR catalyses electron transfer from NADPH to Fd, which then acts as a reductant for various reactions ([@RSTB20090273C115]). In the apicoplast we know of at least three components that require reduced Fd: lipoic acid synthase (LipA), which provides the potent antioxidant lipoic acid to the E2 subunit of the PDH ([@RSTB20090273C106]); and NifU, a protein that provides a scaffold for \[Fe-S\] to assemble on during \[Fe-S\] cluster synthesis; and MiaB, which is probably involved in the modification of tRNAs for apicoplast translation ([@RSTB20090273C56]; [@RSTB20090273C63]). Reactions catalysed by the isoprenoid biosynthetic enzymes, GcpE (IspG) and LytB (IspH), also require reduced Fd. In fact, the FNR/Fd system has been demonstrated to be a functional electron shuttle system for IspH, which is the terminal enzyme in the DOXP pathway catalysing the simultaneous production of IPP and DMAPP ([@RSTB20090273C115]). There is thus a substantial requirement to generate reduced Fd, so where does the NADPH that delivers the electrons to Fd come from? In plants the pentose phosphate pathway can generate NADPH, but no pentose phosphate pathway is apparent in the apicoplast of *P. falciparum* ([@RSTB20090273C56]). Another source of NADPH in plant plastids is part of a plastid glycolytic pathway for the conversion of GA3P to 1,3-diphosphoglycerate (1,3-DPGA) by GAPDH but again this option appears to be lacking in apicoplasts ([@RSTB20090273C56]). At this stage, our best guess for a source of reduced cofactor in the apicoplast is to invoke a reverse direction of the classic redox shuttle that exports reducing power from photosynthetic plastids ([@RSTB20090273C104]). A reverse triose phosphate/3-phosphoglycerate (3-PGA) shuttle has been proposed to transfer triose phosphates from the cytosol to the apicoplast in exchange for 3-PGA, which effectively results in the generation of an ATP and NADPH in the apicoplast by the action of the plastid-localized phosphoglycerate kinase II and GAPDH, respectively ([@RSTB20090273C56]; [@RSTB20090273C104]). Although GAPDH is localized to the apicoplast in *T. gondii* ([@RSTB20090273C104]), this enzyme is not clearly localized to the apicoplasts of other parasites ([table 1](#RSTB20090273TB1){ref-type="table"}). Alternatively, if NADH can be substituted as a reductant for NADPH in the apicoplast of the malaria parasite, the decarboxylation of pyruvate to acetyl-CoA with the generation of NADH from NAD^+^ by the PDH complex offers a potential source of reductant for the organelle. This will, however, cause a build-up of acetyl-CoA which could limit the efficiency of the FASII pathway. The parasite would then have to evolve a mechanism to overcome this, perhaps by extruding the excess acetyl-CoA from the organelle. If acetyl-CoA were exported from the apicoplast, it would presumably need transporters. An attractive, but purely speculative, scenario would be to export surplus acetyl-CoA to the mitochondrion, which lacks a PDH to generate acetyl-CoA for its TCA cycle ([@RSTB20090273C106]). Importing PEP, converting it to pyruvate, then converting the pyruvate to acetyl-CoA that was shuttled to the mitochondrion would provide a means to resolve the ATP and NADH deficits in the apicoplast as well as the presumed acetyl-CoA deficit in the mitochondrion, but the transport of acetyl-CoA across all those membranes remains a hurdle for this postulation. Together with the uniqueness of the plant-type FNR/Fd redox system in the host cell, its involvement in a range of pathways in the apicoplast makes it an attractive drug target ([@RSTB20090273C63]). Probably, the system is also ready for rational drug design since abundant structural information of the individual FNR and Fd in cyanobacteria and plants are available ([@RSTB20090273C64]; [@RSTB20090273C6]; [@RSTB20090273C42]). Since the Fd/FNR redox system is involved in intra-plastid \[Fe-S\] cluster synthesis, its importance is further implicated in the insertion of \[Fe-S\] clusters in several apicoplast enzymes ([@RSTB20090273C56]; [@RSTB20090273C63]). The functional significance of the redox pair has also been unequivocally demonstrated by the elucidation of the molecular interaction of Fd and FNR in *P. falciparum* recently ([@RSTB20090273C28]). 7.. Intracellular role of the apicoplast: unravelling the elusive permeome of the organelle {#s7} =========================================================================================== A potential way to work out the role of the apicoplast within the parasite is to find out what goes in and out of the organelle. By focusing on the gatekeepers---the proteins residing in the apicoplast membranes---we can hope to get a snapshot of exchange between the two partners. The first apicoplast membrane proteins to be identified were PfiTPT and PfoTPT ([@RSTB20090273C43]), and several more membrane proteins have now been uncovered in the apicoplast of *T. gondii*, namely the pPT orthologue TgAPT1 ([@RSTB20090273C27]), a membrane protease TgFtsH1 ([@RSTB20090273C111]), a thioredoxin-like protein ATrx1 ([@RSTB20090273C14]), and apicoplast protein translocation component TgTic20 ([@RSTB20090273C85]), Tic22 ([@RSTB20090273C26]) and Der1 ([@RSTB20090273C26]; [@RSTB20090273C67]). While we have preconceived notions of the functions of TgAPT1, TgTic20, Tic22 and Der1, the roles of TgFtsH1 and ATrx1 are less obvious. With the exception of ATrx1, it appears that corresponding homologues also exist in the genome of *P. falciparum* and it seems likely that the apicoplast membrane complement will be comparable (Karnataki *et al*. [@RSTB20090273C27],[@RSTB20090273C111]; [@RSTB20090273C14]; [@RSTB20090273C33]). Targeting requirements for apicoplast proteins are reasonably well understood for *Plasmodium* and *Toxoplasma*, these being to most tractable systems experimentally. Initially it was thought that apicoplast proteins required a bipartite N-terminal leader for targeting but PfoTPT, which lacks a leader and targets to the outer apicoplast membrane introduced a new paradigm. Bioinformatic searches against the genomes of *P. falciparum* and *T. gondii* for potential apicoplast transporters with a bipartite leader were initially limited to PfiTPT ([@RSTB20090273C56]). As more membrane components are revealed in the apicoplasts of *Plasmodium* and *Toxoplasma*, a new apicoplast-targeting pathway independent of an N-terminal bipartite leader has emerged ([@RSTB20090273C33]). In TgAPT1, TgFtsH1 and ATrx1,
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value_type ().is_a (bool), the method is_a () can't take bool apparently. How can I check if my value is a boolean or not? A: Should be this: if (media.get_value_type () != typeof(bool)) You can use typeof () to get the GType of any data type in Vala and GType is what the function returns. https://wiki.gnome.org/Projects/Vala/FAQ#How_do_I_get_the_GType_for_something.3F https://developer.gnome.org/json-glib/stable/json-glib-JSON-Node.html#json-node-get-value-type In C you would probably use G_TYPE_BOOLEAN: https://developer.gnome.org/gobject/stable/gobject-Type-Information.html#G-TYPE-BOOLEAN:CAPS Objective: Compare factors within and among modern cropping systems that may impact soil microbial communities, plant-microbe interactions, and plant health and productivity. Approach: To assess the weed management legacy on subsequent crops, several agricultural parameters will be measured in glyphosate resistant (GR) and non-GR sweet corn isolines, grown in fields with a legacy of glyphosate use and in fields where glyphosate has not been used for the past three or more years. The field design will allow comparisons of the plant genotype in isolation from the legacy of the farming system management and the plant genotype by systems interactions. Plots will be 15’ wide by 30’ long. For treatments receiving glyphosate, the herbicide will be applied at 0.84 kg a.e. ha-1 in a 130 Lha-1 spray volume at a pressure of 138 kPa when soybean and maize are at the V4–V5 and V5–V6 growth stages, respectively. Plots not receiving glyphosate will be hand-weeded periodically during the growing season. In addition, a subsample of GR and non-GR isolines of sweet corn plants plots will be challenged or not challenged with Goss’s wilt (Clavibacter michiganensis subsp. nebraskensis). Soil and plant samples will be taken at different times throughout the growing season, and shipped to Beltsville, MD for nutrient and microbial analysis.# See absl/copts/copts.py and absl/copts/generate_copts.py include(GENERATED_AbseilCopts) set(ABSL_LSAN_LINKOPTS "") set(ABSL_HAVE_LSAN OFF) set(ABSL_DEFAULT_LINKOPTS "") if (BUILD_SHARED_LIBS AND MSVC) set(ABSL_BUILD_DLL TRUE) set(CMAKE_WINDOWS_EXPORT_ALL_SYMBOLS ON) else() set(ABSL_BUILD_DLL FALSE) endif() if("${CMAKE_SYSTEM_PROCESSOR}" MATCHES "x86_64|amd64|AMD64") if (MSVC) set(ABSL_RANDOM_RANDEN_COPTS "${ABSL_RANDOM_HWAES_MSVC_X64_FLAGS}") else() set(ABSL_RANDOM_RANDEN_COPTS "${ABSL_RANDOM_HWAES_X64_FLAGS}") endif() elseif("${CMAKE_SYSTEM_PROCESSOR}" MATCHES "arm.*|aarch64") if ("${CMAKE_SIZEOF_VOID_P}" STREQUAL "8") set(ABSL_RANDOM_RANDEN_COPTS "${ABSL_RANDOM_HWAES_ARM64_FLAGS}") elseif("${CMAKE_SIZEOF_VOID_P}" STREQUAL "4") set(ABSL_RANDOM_RANDEN_COPTS "${ABSL_RANDOM_HWAES_ARM32_FLAGS}") else() message(WARNING "Value of CMAKE_SIZEOF_VOID_P (${CMAKE_SIZEOF_VOID_P}) is not supported.") endif() else() message(WARNING "Value of CMAKE_SYSTEM_PROCESSOR (${CMAKE_SYSTEM_PROCESSOR}) is unknown and cannot be used to set ABSL_RANDOM_RANDEN_COPTS") set(ABSL_RANDOM_RANDEN_COPTS "") endif() if("${CMAKE_CXX_COMPILER_ID}" STREQUAL "GNU") set(ABSL_DEFAULT_COPTS "${ABSL_GCC_FLAGS}") set(ABSL_TEST_COPTS "${ABSL_GCC_FLAGS};${ABSL_GCC_TEST_FLAGS}") elseif("${CMAKE_CXX_COMPILER_ID}" MATCHES "Clang") # MATCHES so we get both Clang and AppleClang if(MSVC) # clang-cl is half MSVC, half LLVM set(ABSL_DEFAULT_COPTS "${ABSL_CLANG_CL_FLAGS}") set(ABSL_TEST_COPTS "${ABSL_CLANG_CL_FLAGS};${ABSL_CLANG_CL_TEST_FLAGS}") set(ABSL_DEFAULT_LINKOPTS "${ABSL_MSVC_LINKOPTS}") else() set(ABSL_DEFAULT_COPTS "${ABSL_LLVM_FLAGS}") set(ABSL_TEST_COPTS "${ABSL_LLVM_FLAGS};${ABSL_LLVM_TEST_FLAGS}") if("${CMAKE_CXX_COMPILER_ID}" STREQUAL "Clang") # AppleClang doesn't have lsan # https://developer.apple.com/documentation/code_diagnostics if(NOT CMAKE_CXX_COMPILER_VERSION VERSION_LESS 3.5) set(ABSL_LSAN_LINKOPTS "-fsanitize=leak") set(ABSL_HAVE_LSAN ON) endif() endif() endif() elseif("${CMAKE_CXX_COMPILER_ID}" STREQUAL "MSVC") set(ABSL_DEFAULT_COPTS "${ABSL_MSVC_FLAGS}") set(ABSL_TEST_COPTS "${ABSL_MSVC_FLAGS};${ABSL_MSVC_TEST_FLAGS}") set(ABSL_DEFAULT_LINKOPTS "${ABSL_MSVC_LINKOPTS}") else() message(WARNING "Unknown compiler: ${CMAKE_CXX_COMPILER}. Building with no default flags") set(ABSL_DEFAULT_COPTS "") set(ABSL_TEST_COPTS "") endif() set(ABSL_CXX_STANDARD "${CMAKE_CXX_STANDARD}") 1. Introduction =============== Kaempferol, a flavonoid that has been isolated from many plants \[[@B1-molecules-19-16987],[@B2-molecules-19-16987],[@B3-molecules-19-16987],[@B4-molecules-19-16987]\], has many important health-promoting effects, such as antioxidant, antimicrobial, and anti-inflammatory effects, and is known to decrease the risk of cancers, including bladder, colon, and squamous cell cancers \[[@B5-molecules-19-16987],[@B6-molecules-19-16987],[@B7-molecules-19-16987],[@B8-molecules-19-16987],[@B9-molecules-19-16987]\]. Flavonoid glycosides are known to be more abundant than their flavonoid monomers in plants and exhibit a broad range of biological activities. One such flavonoid glycoside, kaempferitrin (kaempferol 3,7-dirhamnoside), has been shown to have a significant hypoglycemic effect and antioxidant properties in humans and is one of the effect factors of auxin transport in plants \[[@B10-molecules-19-16987],[@B11-molecules-19-16987]\]. Biosynthesis of kaempferitrin is one of the sub-pathways of phenylpropanoid biosynthesis. Phenylpropanoids are a diverse group of compounds involved in plant defense, structural support, and survival \[[@B12-molecules-19-16987]\]. Phenylpropanoid biosynthesis starts with the formation of the aromatic amino acid phenylalanine, which is in turn converted into cinnamic acid by phenylalanine ammonia lyase (PAL), the first enzyme in the phenylpropanoid pathway. Cinnamate 4-hydroxylase (C4H) subsequently catalyzes trans-cinnamic acid hydroxylate into *p*-coumaric acid, which is then catalyzed to *p*-coumaroyl-CoA by 4-coumarate-CoA ligase (4CL). *p*-coumaroyl-CoA is the precursor for many phenylpropanoid products, such as lignins and flavonoids.
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:32,316 值得注意的是 Metal 并不会 1331 00:48:32,316 --> 00:48:33,846 区别包含标准数据 1332 00:48:33,846 --> 00:48:36,026 的缓存器和那些 1333 00:48:36,026 --> 00:48:37,176 包含顶点的缓存器 1334 00:48:37,816 --> 00:48:40,276 所以我们会用相同的 API 1335 00:48:40,276 --> 00:48:41,386 去设置标准缓存 1336 00:48:41,386 --> 00:48:44,026 所以这里第一个请求会给 1337 00:48:44,026 --> 00:48:46,026 缓存器访问顶点着色器的权限 1338 00:48:46,026 --> 00:48:47,236 第二个请求会给出访问 1339 00:48:47,236 --> 00:48:48,746 分片着色器的权限 1340 00:48:49,286 --> 00:48:52,166 接下来我们为要去采样的 1341 00:48:52,166 --> 00:48:54,026 分片着色器设定纹理 1342 00:48:54,516 --> 00:48:56,556 然后绘图 1343 00:48:57,076 --> 00:48:59,846 一旦我们完成了编码命令 1344 00:48:59,846 --> 00:49:01,456 我们会通过在编码对象上 1345 00:49:01,456 --> 00:49:03,396 调用 endEncoding 向 Metal 1346 00:49:03,396 --> 00:49:05,376 指出这些 1347 00:49:06,196 --> 00:49:07,916 所以这就是一个简单的 1348 00:49:07,916 --> 00:49:09,406 Metal 渲染通行的例子 1349 00:49:09,926 --> 00:49:12,926 现在我们已经有了一个完整的渲染通行 1350 00:49:12,926 --> 00:49:14,696 我们再来看看怎样去 1351 00:49:14,696 --> 00:49:16,806 让这些渲染表现出来 1352 00:49:17,336 --> 00:49:21,526 通过 OpenGl 你将你的渲染帧 1353 00:49:21,526 --> 00:49:23,156 展现到屏幕上 1354 00:49:23,436 --> 00:49:25,336 但是你并没有明确地管理 1355 00:49:25,336 --> 00:49:27,996 系统的渲染缓存 1356 00:49:27,996 --> 00:49:29,006 依旧被设定为 drawable 1357 00:49:30,336 --> 00:49:32,126 但是要是通过 Metal 将你的 1358 00:49:32,126 --> 00:49:34,476 内容显示在屏幕上 1359 00:49:34,906 --> 00:49:36,186 首先你需要确认包含特殊的纹理 1360 00:49:36,186 --> 00:49:37,516 这种特殊纹理在系统里 1361 00:49:37,516 --> 00:49:39,116 被称为 drawable 1362 00:49:39,746 --> 00:49:41,676 所以你可以使用 MetalKit 视图 1363 00:49:41,816 --> 00:49:42,756 MetalKit 视图提供了每一帧中的 1364 00:49:42,756 --> 00:49:44,846 drawable 纹理 1365 00:49:45,426 --> 00:49:46,886 然后一旦你获得这个 drawable 1366 00:49:46,886 --> 00:49:49,276 你就可以编码渲染通行 1367 00:49:49,276 --> 00:49:51,226 并且渲染到这些 1368 00:49:51,226 --> 00:49:53,096 drawable 就像你 1369 00:49:53,096 --> 00:49:54,586 渲染到任意其他一个纹理一样 1370 00:49:55,126 --> 00:49:57,766 然而并不像其他纹理一样 1371 00:49:57,766 --> 00:49:59,976 现在你可以将这个 drawable 展现出来 1372 00:50:00,096 --> 00:50:02,996 那么让我来给你们展示一下代码例子 1373 00:50:03,516 --> 00:50:06,196 首先我需要说一下 1374 00:50:06,196 --> 00:50:07,886 这些 drawable 受限于你的 1375 00:50:08,166 --> 00:50:10,696 着色器系统资源 1376 00:50:10,696 --> 00:50:12,206 所以你应该尽可能简单 1377 00:50:12,206 --> 00:50:13,536 地处理他们 1378 00:50:14,236 --> 00:50:15,776 这代表着你应该 1379 00:50:15,776 --> 00:50:18,096 在你获取 drawable 以前编码 1380 00:50:18,126 --> 00:50:20,606 所有的离线渲染通行 1381 00:50:21,906 --> 00:50:23,626 之后你可以创建一个 MetalKit 视图 1382 00:50:23,626 --> 00:50:26,856 不但可以去看一个完整的 1383 00:50:26,856 --> 00:50:29,206 填充渲染通行描述符 1384 00:50:29,466 --> 00:50:30,926 这个描述符你可以直接用来 1385 00:50:30,926 --> 00:50:33,836 创建编码器 就是这里你们看到的这个 1386 00:50:33,836 --> 00:50:36,336 同时你还可以通过 1387 00:50:36,336 --> 00:50:37,746 view.currentDrawable 属性 1388 00:50:37,976 --> 00:50:41,626 请求指定的纹理 1389 00:50:41,626 --> 00:50:42,706 之后你可以围绕它创建你自己的 1390 00:50:42,706 --> 00:50:45,086 渲染通行描述符 1391 00:50:47,136 --> 00:50:48,846 一旦你完成了编码你的帧 1392 00:50:48,846 --> 00:50:50,496 你可以调用 1393 00:50:50,496
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FUBeautyParam *param = _dataArray[i]; if (self.mDelegate && [self.mDelegate respondsToSelector:@selector(beautyCollectionView:didSelectedParam:)]) { [self.mDelegate beautyCollectionView:self didSelectedParam:param]; } } } -(void)setupData{ _colors = [NSMutableArray array]; UIColor *color0 = [UIColor whiteColor]; UIColor *color1 = [UIColor colorWithRed:0 green:1.0 blue:0 alpha:1.0]; UIColor *color2 = [UIColor colorWithRed:0 green:0.0 blue:1 alpha:1.0]; [_colors addObject:color0]; [_colors addObject:color1]; [_colors addObject:color2]; } -(void)setupSubView{ _slider = [[FUMakeupSlider alloc] init]; _slider.hidden = YES; [_slider addTarget:self action:@selector(didChangeValue:) forControlEvents:UIControlEventValueChanged]; [_slider addTarget:self action:@selector(didChangeValueEnd:) forControlEvents:UIControlEventTouchUpInside]; [self addSubview:_slider]; _restBtn = [[FUSquareButton alloc] init]; [self addSubview:_restBtn]; [_restBtn setImage:[UIImage imageNamed:@"恢复-0"] forState:UIControlStateNormal]; _restBtn.titleLabel.font = [UIFont systemFontOfSize:10]; // restBtn.alpha = 0.7; [_restBtn addTarget:self action:@selector(resetBtnClick:) forControlEvents:UIControlEventTouchUpInside]; [_restBtn setTitle:@"恢复" forState:UIControlStateNormal]; _sqLine = [[UIView alloc] init]; _sqLine.frame = CGRectMake(73,663,0.5,20); _sqLine.layer.backgroundColor = [UIColor colorWithRed:255/255.0 green:255/255.0 blue:255/255.0 alpha:0.2].CGColor; [self addSubview:_sqLine]; UICollectionViewFlowLayout *layout1 = [[UICollectionViewFlowLayout alloc] init]; layout1.minimumInteritemSpacing = 0; layout1.minimumLineSpacing = 16; layout1.itemSize = CGSizeMake(28, 28); layout1.sectionInset = UIEdgeInsetsMake(0, 20, 0, 20); layout1.scrollDirection = UICollectionViewScrollDirectionHorizontal; _mColorCollectionView = [[UICollectionView alloc] initWithFrame:CGRectZero collectionViewLayout:layout1]; _mColorCollectionView.backgroundColor = [UIColor clearColor]; _mColorCollectionView.delegate = self; _mColorCollectionView.dataSource = self; [self addSubview:_mColorCollectionView]; [_mColorCollectionView registerClass:[FULvMuColorCell class] forCellWithReuseIdentifier:colorCellID]; UIBlurEffect *blur = [UIBlurEffect effectWithStyle:UIBlurEffectStyleDark]; UIVisualEffectView *effectview = [[UIVisualEffectView alloc] initWithEffect:blur]; effectview.alpha = 1.0; [self insertSubview:effectview atIndex:0]; /* 磨玻璃 */ [effectview mas_makeConstraints:^(MASConstraintMaker *make) { make.left.right.bottom.equalTo(self); }]; NSArray *prams = @[@"key_color",@"chroma_thres",@"chroma_thres_T",@"alpha_L"]; NSDictionary *titelDic = @{@"key_color":@"关键颜色",@"chroma_thres":@"相似度",@"chroma_thres_T":@"平滑",@"alpha_L":@"透明度"}; NSDictionary *imageDic = @{@"key_color":@"demo_icon_key_color",@"chroma_thres":@"demo_icon_similarityr",@"chroma_thres_T":@"demo_icon_smooth",@"alpha_L":@"demo_icon_transparency"}; NSDictionary *defaultValueDic = @{@"key_color":@(0),@"chroma_thres":@(0.38),@"chroma_thres_T":@(0.77),@"alpha_L":@(0.80)}; if (!_dataArray) { _dataArray = [[NSMutableArray alloc] init]; } for (NSString *str in prams) { FUBeautyParam *modle = [[FUBeautyParam alloc] init]; modle.mParam = str; modle.mTitle = [titelDic valueForKey:str]; modle.mImageStr = [imageDic valueForKey:str]; modle.mValue = [[defaultValueDic valueForKey:str] floatValue]; modle.defaultValue = modle.mValue; [_dataArray addObject:modle]; } UICollectionViewFlowLayout *layout = [[UICollectionViewFlowLayout alloc] init]; layout.minimumInteritemSpacing = 0; layout.minimumLineSpacing = 30; layout.itemSize = CGSizeMake(44, 60); layout.scrollDirection = UICollectionViewScrollDirectionHorizontal; CGRect frame = CGRectMake(0, 0, [UIScreen mainScreen].bounds.size.width, 80); _mItemCollectionView = [[UICollectionView alloc] initWithFrame:frame collectionViewLayout:layout]; _mItemCollectionView.backgroundColor = [UIColor clearColor]; _mItemCollectionView.delegate = self; _mItemCollectionView.dataSource = self; [self addSubview:_mItemCollectionView]; [_mItemCollectionView registerClass:[FULvMuCell class] forCellWithReuseIdentifier:LvMuCellID]; __weak typeof(self)weakSelf = self ; _segmentBarView = [[FUSegmentBarView alloc] initWithFrame:CGRectMake(0, 200,[UIScreen mainScreen].bounds.size.width, 49) titleArray:@[@"抠像",NSLocalizedString(@"背景",nil)] selBlock:^(int index) { weakSelf.state = index==0? FULvMukeying:FULvMubackground; [weakSelf segmentBarClickUpdateView:weakSelf.state]; [weakSelf hidenTop:NO]; }]; _segmentBarView.backgroundColor = [UIColor clearColor]; [_segmentBarView setUINormal]; [self addSubview:_segmentBarView]; _mBgCollectionView = [[FUBgCollectionView alloc] init]; FUBeautyParam *param1 = [[FUBeautyParam alloc] init]; param1.mTitle = @"沙滩"; param1.mParam = @"beach"; param1.mImageStr = @"demo_bg_beach"; FUBeautyParam *param2 = [[FUBeautyParam alloc] init]; param2.mTitle = @"教师"; param2.mParam = @"classroom"; param2.mImageStr = @"demo_bg_classroom"; FUBeautyParam *param3 = [[FUBeautyParam alloc] init]; param3.mTitle = @"科技"; param3.mParam = @"science"; param3.mImageStr = @"demo_bg_science"; NSArray *params = @[param1,param2,param3]; _mBgCollectionView.filters = params; _mBgCollectionView.mDelegate = self; _mBgCollectionView.hidden = YES; [_mBgCollectionView setSelectedIndex:0]; [self addSubview:_mBgCollectionView]; [_segmentBarView mas_makeConstraints:^(MASConstraintMaker *make) { make.bottom.equalTo(self.mas_bottom); make.left.right.equalTo(self); if (iPhoneXStyle) { make.height.mas_equal
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with Xperia Play: 4/5 Asphalt 6 immerses you in the fast-paced world of street racing, putting you on the edge as you zoom through heavily packed streets around the world. The game boasts impressive graphics and action sequences, which will keep you on your toes as you race your way into the leading position. Racing games on mobile devices have often used the built-in accelerometer to steer your vehicles. Furthermore, traditional methods don't allow much control over accelerating or braking. The Xperia Play changes all that, thanks to the PlayStation controls. Using either the directional keys or analog touch pad, you can steer and avoid oncoming traffic or overtake your opponents. More importantly, drifting and accelerating is made easier with the PlayStation controls, while the shoulder buttons will be often tapped to boost your speed with the nitro power-up. Dungeon Defenders: Second Wave Price: S$12.32 Genre: MMORPG Compatibility with Xperia Play: 3/5 What's it like to spend endless hours, fending off wave after wave of monsters trying to destroy the crystal that you're protecting? The answer to that question can be answered if you play Dungeon Defenders: Second Wave. You'll get to join players from all over the world in an online match to either defend the crystal, or go head-on and battle it out to be the last standing hero. Dungeon Defenders is a game that houses a lot of info on screen. On the usual mobile devices, our thumbs would often block and hinder our actions while we try to move our hero with the on-screen controls. With the Xperia Play, that problem no longer exists. The directional keys now act as shortcuts to perform quick actions that could save your life. The shoulder buttons function as the block and attack action, with the X button being the jump action to get out of a tight situation. Unfortunately, this leaves the analog touch pad as the movement controls, which could lead you to your demise with its insensitive controls.songs in the key of my life Monthly Archives: August 2009 What does it mean to be a South Asian movement organizer pushing for immigration reform in suit and tie meetings while bearing witness to the detention blue button down human casualties of this cold war of words? Comrade Sonny Singh, artist and activist, speaks on this juxtaposition. He calls his essay: Bringing It Home, Out of the Shadows. It was first published on the Sikh Coalition’s blog. By Sonny Singh: Bringing It Home, Out of the Shadows Sonny Singh (Sikh Coalition, Red Baraat) Yesterday afternoon I joined several faith leaders from diverse communities for a meeting with Congressman Anthony Weiner (D-NY) in his district office in Kew Gardens, Queens to discuss immigration reform. The Sikh Coalition is a part of growing group of organizations around the country bringing a faith-based voice to the immigration debate, and in particular has been active in the In the meeting with Congressman Weiner, we discussed what it’s going to take to realistically fix this broken immigration system that has deemed the lives of 12 million undocumented immigrants in this country worthless. 12 million people living in the shadows, at risk of being torn apart from their families and loved ones at any moment. This is a statistic we hear a lot, but as Sikhs, what does it really mean to us? How does it hit home? What is our responsibility as Guru-oriented people? Yesterday it hit home for me. Walking out of a productive meeting towards the bus stop, I felt somewhat hopeful about the progress we might be able to make on this issue in the next year. As I was figuring out which bus to take to get to Richmond Hill, an older desi man with a scruffy beard and short pony tail smiled warmly at me and struck up a conversation in Punjabi. He helped me figure out which bus to get on, and then got on the same bus. I invited him to sit by me. We made small talk for awhile and transitioned to English once my tutti futti (broken) Punjabi wasn’t cutting it any more. Soon enough, he told me that he had just gotten out of jail. Surprised, I asked him what happened and if everything was okay. He responded matter of factly with a story that began with an NYPD officer asked him for ID one night on the subway several months ago and ended with him spending two and a half months incarcerated in an immigrant detention center in Texas. He just got back home last week. Sitting next to me, he was wearing the same thick blue shirt that was given to him in detention. His name is Amarjit Singh, and he is a part of our community. He came to New York over 20 years ago and speaks perfect English. He was born and raised in Delhi and survived the anti-Sikh pograms of 1984 and beyond. He makes a living by selling perfume and handbags. He is a Sikh. He is undocumented. He asked me what he should do. He said he can’t go back to India, that it’s not his home. We talked about the need for an immigration system that recognizes the humanity of all people and provides a path to citizenship. I told him about my work with the Sikh Coalition, which he was excited about. As I was getting off the bus I gave him my card, and he said in Punjabi, “One day, I will call you.” I wish I could have given him a good answer to his question about what he should do, but this immigration system doesn’t have a good answer. As I walked down 95th Avenue towards the gurdwara, my eyes filled with tears, blurring my vision and my optimism. What is going to happen to Amarjit Singh, who has sadly turned to alcohol to drown out his pain and struggle? He was so glad to be “free again,” as he put it, but has no way to even apply to become a legal resident of the United States. He and millions of others will continue living in fear unless we fundamentally change the immigration system. This is a South Asian issue. This is a Punjabi issue. This is an American issue. This is a Sikh issue. A Monday morning peek into news that matters. My father is in town, first thing we both do in the morning is chai and internet. He wants to know who won Sunday’s cricket match between Australia and England. England won. Same diff. I’m on Youtube first thing, wanting to write to the songs I just can’t get outta my head. Like, “Throw It In The Bag (Remix),” by Fabulous and Drake. A bright song, a crystal top spinning kaleidescopes of light. This would be an all time fav…IF it weren’t for the play by play instructions to approach that register, pull out that credit card, and buy into capitalism’s empty win. Shopping. In Other News: President Obama Walks Into A KKK Meeting Disguised As A “Townhall” “So what do you think about the healthcare problem?” “I think all people deserve good care. I think we have the resources, and we sure need new job creation, so an overhaul is possible. But healthcare, like crime & punishment, is one of those issues that reveals how thoroughly this country is in the hands of a few industries. In this case, insurance companies, the medical industrial complex, and big pharma. Generally America keeps a poker face, but some issues make her bleed. Healthcare is blood and guts America, plain and simple.” Thousands of you have viewed this blog and my flickr over the past three days. That lets me know a few things: 1. Desi visibility is on the rise; 2. There is an overwhelming interest in Desi lesbians and gays (LGBTTTSQQ, et al.), what we do, how we do it, and how fabulous we look when we do it; 3. Sepia Mutiny is a cutting edge Desi blog trusted by its readers; 4. Roopa Singh cares about this community and so, her visibility is justly on the rise (that’s me folks)./* * Copyright (c) 2015 Manojkumar Bhosale ([email protected]) * * This file is part of FFmpeg. * * FFmpeg is free software; you can redistribute it and/or * modify it under the terms of the GNU Lesser General Public * License as published by the Free Software Foundation; either * version 2.1 of the License, or (at your option) any later version. * * FFmpeg is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU * Lesser General Public License for more details. * * You should have received a copy of the GNU Lesser General Public * License along with FFmpeg; if not, write to the Free Software * Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301 USA */ #include "libavcodec/vp8dsp.h" #include "libavutil/mips/generic_macros_msa.h" #include "vp8dsp_mips.h
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when compared to the control and higher salinity treatment. In contrast, no differences in pore water Fe^2+^ concentrations between treatments were found for sediment B. Pore water HCO~3~ ^-^ concentrations were significantly higher (p\<0.05) under brackish conditions at sediment B, while no differences were found between treatments at sediment A (data not shown). ![Phosphorus (P) and iron (Fe^2+^) concentrations (µmol L^−1^) in pore water of both sediments (A: left, B: right).\ Significant differences between treatments are indicated with different letters.](pone.0111106.g002){#pone-0111106-g002} Pore water P concentrations showed a gradual decrease at sediment A for all treatments. Moreover, a significantly (p\<0.05) stronger decrease of P in pore water was found for the control treatment, compared to the high and low salinity treatment at sediment A. In strong contrast, P concentrations showed a gradual increase in the pore water of sediment B for all salinity treatments ([Fig. 2](#pone-0111106-g002){ref-type="fig"}), with the significantly (p\<0.05) lowest P concentrations in the high salinity treatment. 3.2 Surface water chemistry {#s3b} --------------------------- A higher salinity led to gradually increased Na^+^ and S concentrations in the surface water, and showed significant (p\<0.005) differences among all treatments, which eventually equalled the concentrations added (S: [Fig. 3](#pone-0111106-g003){ref-type="fig"}; Na^+^: data not shown). For the low salinity treatment, however, S concentrations in the surface water reached much higher concentrations than the concentrations of the treatment water, which suggests S mobilisation from the sediment. These S mobilisation rates were calculated ([Table 3](#pone-0111106-t003){ref-type="table"}) for both a short term, showing significantly (p\<0.005) negative rates at a high salinity (high S consumption) for sediment A, and for a long term, still showing significantly (p\<0.005) negative S mobilisation rates at a high salinity in both sediments. In the surface water, Ca^2+^ concentrations also increased and differed significantly (p\<0.005) among all treatments for both sediments (data not shown). However, both the low and high salinity treatment led to much higher concentrations than the added concentrations. ![Phosphorus (P) and sulphur (S) concentrations (µmol L^−1^) in the surface water above both sediments (A: left, B: right).\ Significant differences between treatments are indicated with different letters. Grey shadings under the x-axis indicate periods with through-flow (see [Materials and Methods](#s2){ref-type="sec"}).](pone.0111106.g003){#pone-0111106-g003} 10.1371/journal.pone.0111106.t003 ###### P and S mobilisation rates (µmol m^−2^ day^−1^) during stagnant conditions in the short term (0--10 weeks) and in the long term (80--110 weeks). ![](pone.0111106.t003){#pone-0111106-t003-3} P mobilisation (µmol m^−2^ day^−1^) S mobilisation (µmol m^−2^ day^−1^) --- --------------- ---------- ------------------------------------- ------------------------------------- ----------------- ----------------- A High salinity **Mean** **6.8** **4.1 ^a^** **−1916.4 ^a^** **−1447.5 ^a^** SEM 1.6 2.4 86.7 243.0 Control **Mean** **37.7** **−1.1 ^ab^** **140.9 ^b^** **−87.0 ^b^** SEM 14.3 0.6 216.0 86.4 Low salinity **Mean** **19.8** **−4.0 ^b^** **−6.5 ^b^** **244.2 ^b^** SEM 12.9 2.3 425.0 69.2 B High salinity **Mean** **16.3** **−2.9** **−8536.5** **−1121.7 ^a^** SEM 24.2 1.0 5474.0 141.3 Control **Mean** **53.3** **−2.2** **−840.4** **123.6 ^b^** SEM 36.6 2.5 517.8 91.1 Low salinity **Mean** **102.6** **−13.1** **−597.4** **294.8 ^b^** SEM 74.3 6.5 236.3 83.3 Significant differences between treatments are indicated by different letters. In the low salinity and control treatment, P concentrations in the surface water increased directly after onset of the treatments (after 10 weeks; t = 0). For the high salinity treatments, P concentrations of the surface water showed a strong and significant (P\<0.05) decrease immediately after the onset of the treatments (after 10 weeks; t = 0). After this temporary decrease, P concentrations started to increase gradually. As a result, significantly lower P concentrations (p\<0.05) were found for the high salinity treatment compared to the low salinity treatment in both sediments at a short term (after 20 weeks; t = 10), and a trend was found when compared to the control treatment (p\<0.1) at sediment A. When P mobilisation rates were calculated for the short term, however, no differences among salinity treatments were found ([Table 3](#pone-0111106-t003){ref-type="table"}). More than 80 weeks after the start of the experiment, P concentrations in the surface water above sediment A were significantly higher (p\<0.01) at a high salinity ([Fig. 3](#pone-0111106-g003){ref-type="fig"}), which was totally opposite to the short-term effect. Calculated P mobilisation rates were also significantly higher (p\<0.05) with a high salinity compared to a low salinity at sediment A. For the control and low salinity treatment, P concentrations in surface water remained low, or even showed a decrease in the long term. At sediment B, however, no change of P in the surface water was found for any of the salinity treatments. The long-term P mobilisation rates with a high salinity were similar to the short-term rates at sediment A, while no long-term P mobilisation was observed for the low salinity and control treatments. 3.3 Aerobic versus anaerobic surface water {#s3c} ------------------------------------------ The O~2~ concentration profile ([Fig. 4](#pone-0111106-g004){ref-type="fig"}) shows that under aerobic conditions, O~2~ is still available in the sediment to an average depth of 7 mm (sediment A) and 3 mm (sediment B). The cores of both sediment A and B showed a significant (p\<0.001) higher mobilisation rate of P during anaerobic conditions ([Fig. 5](#pone-0111106-g005){ref-type="fig"}). At sediment A, P mobilisation was on average 3 times higher during anaerobic conditions compared to aerobic conditions, while this was almost 4 times higher at sediment B. These aerobic mobilisation rates were well within range of the short-term mobilisation rates found in the main experiment (control treatment; [Table 3](#pone-0111106-t003){ref-type="table"}). ![Oxygen (O~2~) concentration (mg L^−1^) profile per mm of both sediments (A and B), at the sediment-water interface (indicated by vertical dotted line) during aerobic and anaerobic conditions.](pone.0111106.g004){#pone-0111106-g004} ![P mobilisation rates (µmol m^−2^ day^−1^) during aerobic and anaerobic conditions for both sediment cores (A and B).\ Significant differences between treatments are indicated with different letters.](pone.0111106.g005){#pone-0111106-g005} Discussion {#s4} ========== 4.1 Short-term effects (0--10 weeks) {#s4a} ------------------------------------ ### 4.1.1 P mobilisation {#s4a1} In the short term, no differences in net mobilisation rates of P were found among the different treatments. During this first stagnant period, moderate P mobilisation rates of 7--103 µmol m^−2^ d^−1^ were found that fitted within the range of Geurts *et al*. [@pone.0111106-Geurts2], who found mobilisation rates of 10--150 µmol m^−2^ d^−1^ for sediments of which pore water Fe:P and total sediment Fe:S ratios were \<1. Diffusion was most
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significant activation to the LC cue while showing no significant suppression to HC cues (Supplementary Fig. [4c, d](#MOESM1){ref-type="media"}). These results suggest that dopamine neurons code and integrate information about both reward and cost at the time of cost cue presentation.Fig. 3Dopamine neuron responses to cost cues. **a** A representative dopamine neuron response to the cost cues. The spike density functions were calculated from the normalized activity of a dopamine neuron recorded from the monkey P. The colored lines indicate the spike density functions and colored dots indicate the spike timing. Green and purple colors indicate activity in the high-cost and low-cost trials, respectively. The vertical line indicates the timing of the cost cue presentation. The gray-colored area indicates the period to calculate the firing rate as the response to the condition cues. **b** Population-averaged activity of the dopamine neurons recorded from monkey P to the condition cues. The solid lines the dashed lines represent mean and SEM, respectively. **c** The distribution of the areas under the ROCs to quantify the effect of the predicted cost on the neuronal response to the cost cue. Filled squares and open circles indicate data from monkey P and S, respectively. The arrowhead indicates the median of the auROC (0.47). **d**, **g** Representative responses of the motivational value type dopamine neuron (**d**) or salience type dopamine neuron (**g**) to the unpredictable reward or air-puff. Red and blue curves indicate the response to unpredictable reward and unpredictable air-puff, respectively. The vertical line indicates the timing of the unpredictable reward or air-puff delivery. Pale red and blue squares indicate the period to calculate the firing rate as the response to the unpredictable reward or air-puff. **e**, **h** Population-averaged activity of the motivational value type dopamine neurons (**e**) or salience type dopamine neurons (**h**) to the unpredictable reward or air-puff. **f**, **i** The distribution of the auROCs calculated from the motivational value type dopamine neurons (**f**) or salience type dopamine neurons (**i**). The arrowheads indicate the medians of the auROCs (**f** 0.48; **i** 0.46) Two distinct subtypes of dopamine neurons have previously been described: motivational value and salience neurons^[@CR28],[@CR29]^. We found evidence in our dopamine neuron population of response patterns consistent with both subtypes. Value type neurons showed phasic suppression to the aversive air-puff stimuli (Fig. [3d, e](#Fig3){ref-type="fig"}). Conversely, salience neurons showed a phasic activation to the aversive stimuli (Fig. [3g, h](#Fig3){ref-type="fig"}). The long fixation in the HC trial is also unpleasant and aversive; therefore, it is possible that the two dopamine neuron subtypes would show different response patterns to the cost condition cues. If dopamine neurons represent aversive stimuli and cost in a similar manner, then value neurons should show decreased activity to the HC cue due to its aversiveness. On the other hand, salience neurons should increase in activity to the HC cue because they also increase to unpleasant stimuli. However, evoked responses of both types of neurons were smaller to the HC cue compared with the LC cue (two-tailed Wilcoxon's signed-rank test; *P* = 0.021, *n* = 41 and *P* = 0.0044, *n* = 29 for the value and the salience types, respectively), and the ROC analysis showed smaller responses to the HC compared to the LC cue in both subtypes (Fig. [3f, i](#Fig3){ref-type="fig"}; two-tailed Wilcoxon's signed-rank test; *P* = 0.030, *n* = 41 and *P* = 0.0058, *n* = 29 for the value and the salience types, respectively). Thus, predicted cost reduced activity in both subtypes of dopamine neurons. These results indicate that cost information is processed by dopamine neurons in a qualitatively different way to aversive stimuli. In the HLC saccade task, we inserted a forced abort in a portion of LC trials to equalize the success rates and the reward probability between trial types. This manipulation increased the uncertainty of obtaining reward or the risk of no reward in the LC condition. Therefore, the higher activity of dopamine neurons and the monkeys' increased valuation for the LC over the HC cue could be due to the difference in the risk or uncertainty between the cost conditions. However, we found no relationship between the number of forced aborts and the difference in RTs (Supplementary Fig. [5a, b](#MOESM1){ref-type="media"}), and we found a positive correlation between the number of forced aborts and the auROC (Supplementary Fig. [5c](#MOESM1){ref-type="media"}). We also compared dopamine responses to the cost cues after aborts vs. after correct trials, but found no difference in both cost conditions (Supplementary Fig. [5d](#MOESM1){ref-type="media"}). These results indicate that the number of forced aborts in the LC condition do not explain either the increase in valuation or the enhanced dopaminergic activation to the LC cue. Increased dopamine responses to reward cue by paid cost {#Sec7} ------------------------------------------------------- The recorded dopamine neurons were found to show phasic activation and suppression to reward and no reward-predicting cues, respectively (Fig. [2](#Fig2){ref-type="fig"}). Next, we assessed whether these responses were modulated by the cost previously incurred. An example of a representative neuron and population-averaged neurons exhibiting larger activation to the R~HC~+ cue than the R~LC~+ cue are shown in Figure [4a and b, respectively](#Fig4){ref-type="fig"}. (two-tailed Wilcoxon's signed-rank test; *P* = 7.4 × 10^−5^, *n* = 70). The distribution of auROCs was \>0.5, indicating that the response to the R~HC~+ cue was larger than to the R~LC~+ cue (Fig. [4c](#Fig4){ref-type="fig"}; two-tailed Wilcoxon's signed-rank test; *P* = 1.4 × 10^−4^, *n* = 70). These results indicate that the response to the reward-predicting cue in the HC condition is significantly larger than in the LC condition. Therefore, our findings suggest that the positive-RPE signal represented by dopamine neurons is increased by the cost previously incurred.Fig. 4Dopamine neuron responses to reward cues. **a** An example neuron response to the R+ cues. The spike density functions were calculated from the activity of dopamine neuron recorded from monkey P. The colored lines and dots indicate spike density and spike timing, respectively. Yellow and pink colors indicate activity in the high-cost and low-cost trials, respectively. The vertical line indicates the timing of the R+ cue presentation. The gray-colored area indicates the period to calculate the firing rate as the response to the reward cues. **b** Population-averaged activity of the dopamine neurons recorded from monkey P to the R+ cues. The solid lines and the dashed lines represent mean and SEM, respectively. **c** The distribution of the auROCs to quantify the effect of the paid cost on the neuronal response to the R+ cues. Filled squares and open circles indicate data from monkey P and S, respectively. The arrowhead indicates the median of the auROCs (0.53). **d** A representative response to the R− cues. Green and cyan colors indicate high-cost and low-cost trials, respectively. The vertical line indicates the timing of the R− cue presentation. **e** Population-averaged activity of the dopamine neurons recorded from monkey P to the R− cues. **f** The distribution of the auROCs to quantify the effect of the paid cost on the neuronal response to the R− cues. The arrowhead indicates the median of the auROC (0.50) The dopamine neurons also showed phasic suppression to the R− cues (Fig. [4d, e](#Fig4){ref-type="fig"}). However, the responses of the dopamine neurons to the R− cues did not show a significant difference as a function of cost incurred (two-tailed Wilcoxon's signed-rank test; *P* = 0.25, *n* = 70), and the ROC analysis did not reveal any evidence for a bias in the response distribution (Fig. [4f](#Fig4){ref-type="fig"}; Wilcoxon's signed-rank test, *P* = 0.35; *n* = 70). Thus, the paid cost was not reflected in the negative-RPE signal elicited by the nonreward-predicting cues. This may be caused by a floor effect: the spontaneous activity of the dopamine neuron is low (around 5 Hz); and consequently there may not be a sufficient dynamic range to adequately encode any such difference in cost expended for the negative RPE response (Fig. [4d, e](#Fig4){ref-type="fig"}). We also examined the effect of the paid cost on the reward cues for the value and salience type dopamine neurons separately, but both types of dopamine neurons showed similar response pattern (Supplementary Fig. [6a--h](#MOESM1){ref-type="media"}). Therefore, the paid cost manifests a
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must be regularized to be justified. We examine one possible method of regularization and show that the proposed method gives traditional quantum mechanics results.' address: - 'Department of Physics and Astronomy, University of South Carolina, Columbia, SC 29208.' - 'Newman Laboratory of Nuclear Studies, Cornell University, Ithaca, NY 14853.' - 'SISSA, Via Beirut 4, 34013 Trieste, Italy.' author: - 'C.K. Au' - 'Chi–Keung Chow' - 'Chong–Sun Chu' title: 'Comment on “A new efficient method for calculating perturbative energies using functions which are not square integrable”: regularization and justification' --- Recently, in a letter in this journal [@SC], Skála and Čížek (SC) proposed a method to calculate perturbation energies using non-sqaure-integrable functions. The method of SC is further augmented in a comment by Guardiola and Ros (GR) [@GR]. The purpose of our present comment is to further point out that in a strict sense, the SC method for the perturbation energies can result in a ratio of two divergent quantities, so that while this ratio may remain finite in a practical numerical calculation, a regularization procedure is needed to justify the finite result. We have examined one such possible regularization procedure and made contact between the SC method and traditional quantum mechanics (QM) results. Briefly, the SC method regards the $n$-th order perturbation equation as a parametric differential equation with $E_n$ as the parameter, $$(H_0 - E_0) \psi_n (E_n,x) = (E_n - \tilde V_n) \psi_0 (x), \label{master}$$ where $$H_0= -\frac{d^2}{dx^2} +V_0,$$ and $$\tilde V_n \psi_0 \equiv V_1 \psi_{n-1} - \sum_{i=1}^{n-1} E_i \psi_{n-i}. \label{defV}$$ Here we have chosen to introduce $\tilde V_n$ as the effective perturbation in the $n$-th order equation. For $n=1$, the sum in R.H.S. of Eq. (\[defV\]) vanishes and $\tilde V_1$ is the same as the real perturbation $V_1$. We also adopt the convention that all the wavefunctions are physical unless the dependence on the parameter $E_n$ is explicitly displayed. For this form of Eq. (\[master\]), the $n$-th order equation is similar in form to the first order equation. $\tilde V_n$ is a known function since all lower order quantities are assumed known. In traditional QM perturbation theory, one left multiplies Eq. (\[master\]) with the zeroth order wave function $\psi_0$. Under the usual normalization conditions, $$\langle \psi_0|\psi_0 \rangle = 1 \qquad \hbox{and} \qquad \langle \psi_0|\psi_i \rangle = 0 \quad \forall i \neq 0, \label{norm}$$ one recovers the standard QM result $$E_n = \langle \psi_0 |\tilde V_n| \psi_0 \rangle = \langle \psi_0 |V_1| \psi_{n-1} \rangle.$$ Once $E_n$ is correctly obtained, $\psi_n(E_n, x)$ is obtained by solving the ordinary differential equation in Eq. (\[master\]). SC propose that instead of obtaining $E_n$ in the standard way first, one treats Eq. (\[master\]) as a parametric ordinary differential equation with $E_n$ a parameter, and go on to show that $$E_n = {- \psi_n(0, x_0)\over \psi_n (1, x_0) - \psi_n (0, x_0)} \equiv {- \psi_n(0, x_0)\over F(x_0)}, \label{para}$$ where $x_0$ is a point such that the boundary conditions $$\psi_n(E_n,x_0) = 0, \qquad n = 0,1, \dots \label{bc}$$ are met for the physicsal energies $E_n$. Since neither 0 nor 1 is the necessary $n$-th order energy correction $E_n$, the functions $\psi_n(0, x)$ and $\psi_n(1, x)$ are in general [*not*]{} square integrable and hence the name for the method. Since the ground state wave function vanishes only at the end points of the boundary[^1] and the nodal points of the wave functions of the excited states shift upon turning on the perturbation, the [*only*]{} choice for $x_0$ consistent with the boundary conditions (\[bc\]) is $x_0=\infty$. In a practical numerical calculation, which is always carried out in between finite ranges, $x_0$ is assigned an arbitrarily large but finite value. But as $x_0$ approaches infinity, both $\psi_n(0, x_0)$ and $\psi_n(1, x_0)$ diverge, and a regularization process is needed to make sense of Eq. (\[para\]). In the form of Eq. (\[master\]), taking into account of the advantage of its similarity in form to the first order equation, $\psi_n(\alpha, x)$ can easily be solved, say, using the Dalgarno–Lewis method [@DL] or logarithmic perturbation method [@AA; @Tu] to obtain, $$\psi_n(\alpha,x) = - \psi_0(x) \int_b^x dy\, {1\over \psi_0^2(y)} \int_a^y dz \,(\alpha - \tilde V_n) \psi_0^2(z) , \label{sol}$$ where $a$ and $b$ are appropriate constants to satisfy the boundary conditions, in agreement with the results of GR. From Eq. (\[sol\]), one recovers the universal functions $F(x)$ (given as Eq. (15) in Ref. [@GR]) $$F(x) = - \psi_0(x) \int_b^x dy \,{1\over \psi_0^2(y)} \int_a^y dz \,V(z) \psi_0^2(z).$$ Together with Eq. (\[para\]), one sees that the $n$-th order perturbation energy $E_n$ is given by $$E_n = {J(\tilde V_n, x_0)\over J(1, x_0)}, \label{En}$$ where the functional $J(V,x)$ is given by $$J(V,x) \equiv \int_0^x dy \,{1\over \psi_0^2(y)} \int_0^y dz \,V(z) \psi_0^2(z). \label{J}$$ and the boundary condition at the endpoints has been taken care of appropriately. Next, we would like to point out that at least in the example of the ground state of the $x^4$ anharmonic oscillator, the expansion of $E_n$ in Eq. (\[En\]) can be ill-defined because both the numerator and the denominator diverge as $x_0 \to\infty$. This can be easily seen by combining the well-known results that $\tilde V_n$ is of polynomial form in the Bender–Wu [@BW] $x^4$ anharmonic oscillator and the mean value theorem. From the form of Eq. (\[J\]), one does [*not*]{} expect [*a priori*]{} that in the limit $x_0 \to \infty$, the ratio $J(\tilde V_n, x_0)/J(1, x_0)$ becomes finite and $x_0$ independent even though numerically this comes out to be so. Hence to make sense out of Eqs. (\[En\]) and (\[J\]), a regularization procedure is in order. One can justify the numerical result obtained by assigning an arbitrarily large but finite value to $x_0$ only after the result is regularized and the limit is proven to exist. The regularization procedure being proposed here is similar to the one we previously used in the extension of logarithmic perturbation theory to excited bound states in one dimension by appropriately mixing in the ghost state [@We]. For the zeroth order solution (unperturbed state), instead of using the square integrable eigenstate wave function $\psi_0$, we can mix in the non-square-integrable ghost state $\chi_0$ by defining $$\Psi_0(x) \equiv \psi_0(x) + i\sigma\chi_0(x),$$ $$\rho(x) \equiv \Psi_0^2(x). \label{rho}$$ and $$J_\sigma[S] \equiv \int_0^\infty dy \,{1\over\rho(y)} \int_0^y dz \, \rho(z) S(z).$$ Note that in Eq. (\[rho\]), $\rho(x)$ is the ordinary square of $\Psi_0(x)$, not $|\Psi_0(x)|^2$. Then Eq. (\[En\]) can be rewritten on
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bés son muy fáciles de conseguir de segunda mano. Por supuesto, una manera fácil de obtener los suministros que necesita es crear una lista de deseos de Amazon Puede compartirlo en línea con sus amigos, familiares o compañeros de trabajo. Y te sorprenderá cuántas personas están dispuestas a ayudar Especialmente cuando saben que obtendrán muchos videos lindos de gatitos a cambio Y finalmente mi cosa favorita es una "kitten shower" (fiesta de regalos para gatitos) al igual que un baby shower regala suministros para bebés a nuevos padres Una "kitten shower" (fiesta de regalos para gatitos) da suministros de gatitos a los nuevos padres adoptivos ¿Y quién no quiere ir a una fiesta de regalos para gatitos? Simplemente haga una lista de todas las cosas que necesita Invita a tus amigos a venir a tu casa y te sorprenderá cuántas personas te apoyarán. Una vez que las personas en tu vida sepan que estás salvando vidas de gatitos Muchos de ellos lo apoyarán en sus esfuerzos y lo ayudarán en el camino ¡Eso es todo! Ahora sabes cómo configurar tu espacio para gatitos adoptivos Ya sea que estés criando pequeños gatitos French: Étant donné que pas mal de fournitures dont vous aurez besoin sont des fournitures pour bébé Les choses comme les animaux en peluche et les couvertures pour bébés sont vraiment faciles à trouver en seconde main Bien sûr, un moyen simple d'obtenir les fournitures dont vous avez besoin consiste à créer une liste de souhaits Amazon. Vous pouvez le partager en ligne avec vos amis, votre famille ou vos collègues. Et vous serez surpris de voir combien de personnes sont disposées à aider Surtout quand ils savent qu'ils vont avoir beaucoup de vidéos de mignons chatons en retour Et finalement mon truc préféré est une fête pour chaton comme une fête de naissance avec des cadeaux pour bébé aux nouveaux parents Une fête pour chaton offre du matériel pour chaton aux nouveaux parents d'accueil Et qui ne veut pas aller à une fête de chaton? Faites juste une liste de tout ce dont vous avez besoin Invitez vos amis à venir chez vous et vous seriez surpris de voir combien de personnes vous soutiendront Une fois que les gens dans votre vie savent que vous sauvez la vie de chatons Beaucoup d’entre eux vont vous soutenir dans vos efforts et vous aider tout au long du chemin Alors c'est tout! Maintenant, vous savez comment configurer votre espace pour les chatons Que vous éleviez de minuscules chatons German: Und weil sehr viele Sachen, die du brauchst, für Babies sind Bekommst du viele Sachen wie Plüschtiere und Babydecken in Secondhand Läden Eine einfache Möglichkeit, um an dein Material zu kommen ist, eine Amazon wishlist zu erstellen Du kannst die Liste mit deinen Freunden oder Arbeitsfreunde teilen Und du wirst dich wundern, wie viele gerne helfen Speziell wenn sie wissen, dass sie dafür viele süsse Katzenvideos sehen werden Und zuletzt: mein Lieblingsevent ist eine kitten-shower zu organiseren Wie es bei einem Baby-Shower Geschenke für die neuen Eltern gibt Bringt man den Pflegeeltern der Kätzchen Geschenke für diese Und wer möchte nicht an eine Kitten-Shower gehen? Stelle einfach eine Liste mit all den Dingen zusammen, die du brauchst Lade deine Freunde zu dir nach Hause ein und du wirst verwundert sein, wie viele Leute dir helfen möchten Wenn die Personen in deinem Leben einmal erfahren, dass du kleine Kätzchen rettest Werden dich viele in deinen Bemühungen helfen Das ist es schon! Jetzt weisst du, wie du den Platz für deine Pflegekätzchen vorbereitest Ob du nun klitzekleine Kätzchen pflegst English: Since so many of the supplies you're going to need are baby supplies The things like stuffed animals and baby blankets are really easy to come by second hand Of course an easy way to get the supplies that you need is to create an Amazon wishlist You can share it online with your friends or family or coworkers And you'll be surprised how many people are willing to help out Especially when they know they're going to get lots of cute kitten videos in return And finally my favorite thing is a kitten shower just like a baby shower gifts baby supplies to new parents A kitten shower gives kitten supplies to new foster parents And who doesn't want to go to a kitten shower? Just make a list of all of the things that you need Invite your friends to come over to your house and you'd be surprised how many people will support you Once the people in your life know that you're saving kittens lives So many of them are going to support you in your efforts and help you along the way So that's it! Now you know how to set up your space for foster kittens Whether you're fostering teeny tiny kittens Spanish: o gatitos mayores que están casi listos para la adopción Ahora sabes lo que necesitan para mantenerlos seguros, cómodos y saludables. Pumpkin, no mastica a ese, bebé Te amo, no mastiques eso 🐱 Serbian: ili starijim macama koje su spremne za udomljavanje znate šta je potrebno da im bude udobno i da su zdrave Pumpkin ne žvaći to Volim te, nemoj da žvaćeš to <3 🐱 German: oder grössere Katzen, die bereit für eine Adoption sind Weisst du jetzt, was du brauchst, um sie sicher, gemütlich und gesund zu halten Pumpkin, kau das bitte nicht Baby Ich liebe dich, kau das nicht French: ou des chatons presque prêts à être adoptés Maintenant, vous savez ce dont ils ont besoin pour être en sécurité, confortables et en bonne santé Pumpkin, ne mâche pas cela, bébé Je t'aime, ne mâche pas ça 🐱 English: or older kittens who are almost ready for adoption Now you know what they need to keep them safe comfy and healthy Pumpkin don't chew that baby I love you, don't chew that 🐱 Spanish: o gatitos mayores que están casi listos para su adopción Ahora sabes lo que necesitas para mantenerlos seguros, cómodos y saludables Pumpkin, no muerdas eso bebé Te amo, no muerdas eso 🐱 Menu Welcome to Dalriada! We are an award-winning family run bar situated right on the beach in Edinburgh’s Portobello, enjoying panoramic views over the Firth of Forth. We have a large beer garden opening onto the beach, and a cosy cider garden at the back. Warm yourself by our real fire with a freshly ground coffee or choose from our wide selection of real ales, wines and spirits. We serve homemade soups, toasted paninis and lightbites every weekend until 3pm. Live Music Wed – Sun Wednesday Night Trad Session – Every week from 8 – 10pm Blursday – Acoustic session led by multi- instrumentalist Mike Kearney – Every Thurs 9pm -12am The Friday Fireside Session – Join in with Pat and the gang! – Every Week from 9pm-12am The Saturday Afternoon Trad Session – Led by Sean
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b'\xa6' : '|', b'\xa7' : 'S', b'\xa8' : '..', b'\xa9' : '', b'\xaa' : '(th)', b'\xab' : '<<', b'\xac' : '!', b'\xad' : ' ', b'\xae' : '(R)', b'\xaf' : '-', b'\xb0' : 'o', b'\xb1' : '+-', b'\xb2' : '2', b'\xb3' : '3', b'\xb4' : ("'", 'acute'), b'\xb5' : 'u', b'\xb6' : 'P', b'\xb7' : '*', b'\xb8' : ',', b'\xb9' : '1', b'\xba' : '(th)', b'\xbb' : '>>', b'\xbc' : '1/4', b'\xbd' : '1/2', b'\xbe' : '3/4', b'\xbf' : '?', b'\xc0' : 'A', b'\xc1' : 'A', b'\xc2' : 'A', b'\xc3' : 'A', b'\xc4' : 'A', b'\xc5' : 'A', b'\xc6' : 'AE', b'\xc7' : 'C', b'\xc8' : 'E', b'\xc9' : 'E', b'\xca' : 'E', b'\xcb' : 'E', b'\xcc' : 'I', b'\xcd' : 'I', b'\xce' : 'I', b'\xcf' : 'I', b'\xd0' : 'D', b'\xd1' : 'N', b'\xd2' : 'O', b'\xd3' : 'O', b'\xd4' : 'O', b'\xd5' : 'O', b'\xd6' : 'O', b'\xd7' : '*', b'\xd8' : 'O', b'\xd9' : 'U', b'\xda' : 'U', b'\xdb' : 'U', b'\xdc' : 'U', b'\xdd' : 'Y', b'\xde' : 'b', b'\xdf' : 'B', b'\xe0' : 'a', b'\xe1' : 'a', b'\xe2' : 'a', b'\xe3' : 'a', b'\xe4' : 'a', b'\xe5' : 'a', b'\xe6' : 'ae', b'\xe7' : 'c', b'\xe8' : 'e', b'\xe9' : 'e', b'\xea' : 'e', b'\xeb' : 'e', b'\xec' : 'i', b'\xed' : 'i', b'\xee' : 'i', b'\xef' : 'i', b'\xf0' : 'o', b'\xf1' : 'n', b'\xf2' : 'o', b'\xf3' : 'o', b'\xf4' : 'o', b'\xf5' : 'o', b'\xf6' : 'o', b'\xf7' : '/', b'\xf8' : 'o', b'\xf9' : 'u', b'\xfa' : 'u', b'\xfb' : 'u', b'\xfc' : 'u', b'\xfd' : 'y', b'\xfe' : 'b', b'\xff' : 'y', } # A map used when removing rogue Windows-1252/ISO-8859-1 # characters in otherwise UTF-8 documents. # # Note that \x81, \x8d, \x8f, \x90, and \x9d are undefined in # Windows-1252. WINDOWS_1252_TO_UTF8 = { 0x80 : b'\xe2\x82\xac', # € 0x82 : b'\xe2\x80\x9a', # ‚ 0x83 : b'\xc6\x92', # ƒ 0x84 : b'\xe2\x80\x9e', # „ 0x85 : b'\xe2\x80\xa6', # … 0x86 : b'\xe2\x80\xa0', # † 0x87 : b'\xe2\x80\xa1', # ‡ 0x88 : b'\xcb\x86', # ˆ 0x89 : b'\xe2\x80\xb0', # ‰ 0x8a : b'\xc5\xa0', # Š 0x8b : b'\xe2\x80\xb9', # ‹ 0x8c : b'\xc5\x92', # Œ 0x8e : b'\xc5\xbd', # Ž 0x91 : b'\xe2\x80\x98', # ‘ 0x92 : b'\xe2\x80\x99', # ’ 0x93 : b'\xe2\x80\x9c', # “ 0x94 : b'\xe2\x80\x9d', # ” 0x95 : b'\xe2\x80\xa2', # • 0x96 : b'\xe2\x80\x93', # – 0x97 : b'\xe2\x80\x94', # — 0x98 : b'\xcb\x9c', # ˜ 0x99 : b'\xe2\x84\xa2', # ™ 0x9a : b'\xc5\xa1', # š 0x9b : b'\xe2\x80\xba', # › 0x9c : b'\xc5\x93', # œ 0x9e : b'\xc5\xbe', # ž 0x9f : b'\xc5\xb8', # Ÿ 0xa0 : b'\xc2\xa0', #   0xa1 : b'\xc2\xa1', # ¡ 0xa2 : b'\xc2\xa2', # ¢ 0xa3 : b'\xc2\xa3', # £ 0xa4 : b'\xc2\xa4', # ¤ 0xa5 : b'\xc2\xa5', # ¥ 0xa6 : b'\xc2\xa6', # ¦ 0xa7 : b'\xc2\xa7', # § 0xa8 : b'\xc2\xa8', # ¨ 0xa9 : b'\xc2\xa9', # © 0xaa : b'\xc2\xaa', # ª 0xab : b'\xc2\xab', # « 0xac : b'\xc2\xac', # ¬ 0xad : b'\xc2\xad', # ­ 0xae : b'\xc2\xae', # ® 0xaf : b'\xc2\xaf', # ¯ 0xb0 : b'\xc2\xb0', # ° 0xb1 : b'\xc2\xb1', # ± 0xb2 : b'\xc2\xb2', # ² 0xb3 : b'\xc2\xb3', # ³ 0xb4 : b'\xc2\xb4', # ´ 0xb5 : b'\xc2\xb5', # µ 0xb6 : b'\xc2\xb6', # ¶ 0xb7 : b'\xc2\xb7', # · 0xb8 : b'\xc2\xb8', # ¸ 0xb9 : b'\
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favoráveis é de 7,16% do total enquanto o uso de robôs no contingente de interações desfavoráveis é de 12,97%. Vale interpretar dois aspectos desses percentuais apontados pelo estudo: de que pelo levantamento feito pela FGV, em relação ao volume de interação de cada grupo (favoráveis e desfavoráveis) mostra que o uso de robôs em favor da exposição é infinitamente menor comparativamente ao volume de apoiadores, e o de robôs contra a exposição é praticamente da mesma escala se comparado ao todo de interações desfavoráveis. Isso mostra que de fato uma imensa maioria que se manifestou era a favor da exposição. Um outro aspecto a ser observado é que segundo o mesmo levantamento, o grupo de apoio à Queermuseu apresenta 'maior diversidade de argumentos' que o grupo contrario a ela, o que parece ser uma evidência de que no grupo contrario, onde se identifica uma imensa maioria de atividades de robôs, há um menor numero de fontes de emissão das interações, apontando para um ataque concatenado e planejado.Q: Dynamic iBeacons and Manual Input of UUIDs I'm working on an app that retrieves iBeacon UUIDs from a backend server, that means there are no hard-coded UUIDs in the app and these IDs are constantly changing. UUIDs can be updated on the backend and the app will receive a new set of UUIDs to monitor for. Based on this post here, Apple is rejecting apps that support manual input of UUIDs and I'm not sure if my app is going to make it to the App store. I would like to hear your feedback if you've gone through this path or have worked on a similar concept and made it through the review process. A: I have also had an app rejected for allowing manual input of ProximityUUIDs. My understanding of Apple's position is that this applies only to transmitting as a beacon, and that it is allowed to have manual user input of ProximityUUIDs for detection purposes. The reason they don't want you to transmit with a manually entered ProximityUUIDs is because it allows creation of an easy hacker tool for "spoofing" other folks' beacons. That said, your use case is different still, because you are getting the ProximityUUIDs from a server, not directly from user input. I have several apps in the AppStore that do exactly this, and it is a common practice, so I don't anticipate it will be a problem for you. Referring physicians' perceived benefits of PACS: a regional survey pre- and post-PACS implementation. Referring physicians in theWestern Health Authority of Newfoundland and Labrador were administered a survey before and after PACS was implemented across all acute sites in the province.The survey had 31.7% and 35.0% response rates, respectively. There was considerable support found for PACS both pre- and post-implementation in the areas of exam access and review, PACS functionality, quality of reports, efficiency, and site-to-site professional consultations.There was limited support that PACS reduced hospital length of stay. Surveys such as the one employed in this study provide an opportunity to measure the perceived benefit and challenges of PACS in a relatively cost effective manner.The universe is neutral and uncaring; there are no divine rewards or punishments for earthly deeds. Nature is inherently violent; things need to feed off of other things, and destroy or kill other things, in order to survive and prosper. In human conflicts, whoever is stronger wins; he destroys his enemy and lives to fight another day. This is the way it works regardless of who was morally right, in the usual sense of morality. This we can altogether say is the Law of the Jungle. As a Satanist, I know that's how the universe works, and I play accordingly. (In many more detailed manners of social interaction and personal advancement there's no need to elaborate on here.) But now, do I want to live in a human society which goes by a philosophy of "might makes right, anything goes, Law of the Jungle"? I will say simply, "no," but with qualifications. "No" because such a society doesn't help my own survival much, it hinders it. As a rational social animal, I want to live in a society which has mechanisms (police, courts, armies,) to protect my freedom. Sure, in a state of nature, and when it REALLY comes down to it all I can rely on is myself to survive against attackers and natural disasters, but why would I want to live day in and day out in constant fear for my life? I will personally take steps to protect myself with a firearm and some common-sense "street smarts," but as really an extension of this, I will also politically support a government and society which punishes criminals for me as a deterrent against crime, and provides disaster relief services, among other useful social constructs to protect me against dangers. I even go so far as to support government policie which help my own survival and well-being in the form of safety regulations and national health insurance. Is this breaking the "Law of the Jungle?" No. It's still recognizing it as fundamentally true, empirically of nature, while putting plans in place to protect ME. It's pragmatic survival. Now those qualifications I talked about; I don't want everyone to survive and get a basic income just because they have a pulse. Criminals and drug-addicts I can immediately single out as being undeserving of most, if not all, (depending on some specifics of crimes) social protections. I still want Lex Talionis implemented in law and punishment. In economic matters, I do generally want companies which fail to fail; creative destruction, better ones will take their place. My point here is that while the universe is uncaring and one needs to know it and act on it, it also behooves one to put in place certain social constructs to protect one's freedom and well-being. (The specifics of this are of course endlessly debated in the political sphere, I have my specific views on political issues which will of course differ from the next Satainst. The principle is just SOME sort of security put together by government, which may vary in reach and specific areas.) I don't want to be wiped out by ever plague and war that stabilizes populations; I want to live long and prosper no matter what. You can see from this why it should be upsetting to a Satanist to hear stories of people harmed by incompetent or corrupt hospital staff, police officers, and bureaucrats of all sorts; it bodes badly for the individual Satanist. Yes; be prepared personally, ultimately you're reponsible for yourself...but having a completely assholy, boastfully "UNCARING" attitude towards people dying or being treated wrongfully due largely to the failings of professionals paid to serve them is foolhardy. You never know when you might get hit by any number of idiot drunk drivers, or falsely accused of crimes yourself. Professional effectiveness and justice in society are valuable to all, including me, therefore I do care. Another thing too; might does not make right in any kind of real morality. If someone robbed you, or raped you, you'd never consider it right just on account of the perpetrator being bigger than you; you'd consider it wrong on account of it being wrong. "Might is Right" is true in that the victor gets the spoils, and this must always be remembered, but it is not morality in any useful sense. It is a useful phrase for the nature of reality on the most inhuman level, before we start putting our own hierarchy of values of justice onto actions and objects. Objective morality does exist, independent of any god or divine creation, and is discoverable by scientific inquiry; ethics. Still, nothing bad happens kharmically or when you die because of what you did morally, but morality can be discovered. I'm going off on a tangent there though; my point here was that it's foolish to want the Law of the Jungle to apply freely to oneself. I will personally take steps to protect myself with a firearm and some common-sense "street smarts," but as really an extension of this, I will also politically support a government and society which punishes criminals for me as a deterrent against crime, and provides disaster relief services, among other useful social constructs to protect me against dangers. Agreed. Originally Posted By: Labyrinthine In human conflicts, whoever is stronger wins Yes, but I think "stronger" should be used in a very liberal sense. Survival of the fittest does not necessarily mean survival of the physically strongest. Physical strength is only one factor. A strong intellect and strong cunning can go a long way, especially for our species. Also, merely accepting the whole "might is right" mentality does not make one mighty, although merely recognizing the importance of social dominance may at least help a person in one's decisions. Originally Posted By: Lab
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type in Eq. (\[substi\]) in so far as $$g(x)= N_n \sqrt{x^{\beta }e^{-x}}L(x) /\sqrt{\frac{d}{dx}\sqrt{x}},$$ where one recognizes the square root of the weight function of the associated Laguerre polynomials in front of $L(x)$. The difference between $N_n$ and $K_n$ accounts for possible constants emerging from the inverse of the derivative of $f(x)$. In effect, one arrives at $$xL''(x)+(\beta+1-x)L'(x)+\left( \frac{4\beta^{2}-4l(l+1)-1}{4x}+ \frac{\epsilon}{4} -\frac{\beta}{2}-\frac{1}{2} \right)L(x)=0. \label{Lag_1}$$ Now we make use of the freedom in $\beta$ to nullify the singularity by setting $\beta= l+ \frac{1}{2}$ and thus, we are left with the equation for the associated Laguerre polynomials, equation (\[lagRaposo\]). Therefore $$\frac{\epsilon}{4} -\frac{\beta}{2}-\frac{1}{2}=n, \quad 4\beta^{2}-4l(l+1)-1=0, \label{Lag_2}$$ allows to identify Eq. (\[Lag\_1\]) with the equation for the associated Laguerre polynomials, $$xL''_{n}(x)+(l+\frac{1}{2}+1-x)L'_{n}(x)+nL_{n}(x)=0, \label{Lag_3}$$ whose solutions are $L_{n}(x)= L^{\left( l+\frac{1}{2}\right)}_{n}(x)$. In effect, the radial part of the Schrödinger wave function for the $3D$ oscillator is given as $$g_n(x)=N_n\sqrt{x^{l+\frac{1}{2}}e^{-x}}L_n^{\left(l+\frac{1}{2}\right)}(x) /\sqrt{\frac{d}{dx} \sqrt{x}}.$$ Back to the $z$ variable, the Schrödinger wave function is now obtained in its final form as $$\psi_n(z)=\frac{R(z)}{z}= K_n z^{l}e^{-\frac{z^{2}}{2}}L^{(l+\frac{1}{2})}_{n}(z^{2}).$$ The orthogonality integral between the wave functions recovers the orthogonality between the Laguerre polynomials according to $$\int_0^\infty R_n(z) R_{n}(z)dz= \int_0^\infty K_n K_{n^\prime} \sqrt{x^{l+\frac{1}{2}}e^{-x}}L_n^{\left(l+\frac{1}{2}\right)}(x) \sqrt{x^{l+\frac{1}{2}}e^{-x}}L_{n^\prime}^{\left(l+\frac{1}{2}\right)}(x) dx =\delta_{nn^\prime}\, , \label{orth_3d_HO}$$ where $dz=d\sqrt{x}$. The energies are now given by $\epsilon_n=2(2n+l+\frac{3}{2})$. The reason for which the associated, and not the ordinary Laguerre polynomials appeared in the solution of the $3D$ oscillator is that the angular momentum, $l$, requires a polynomial parameter. ### The hydrogen atom. ![Coulomb potential (dashed line), $V(r)=-\frac{Ze^{2}}{r}$. The effective potential (solid line), $V_{eff}(r)=-\frac{Ze^{2}}{r}+\frac{l(l+1)}{r^{2}}$ includes the centrifugal barrier. Here $Ze^{2}=10$ and $l=1$.\[PotencialCoulomb\]](PotencialCoulomb.ps){width="7"} In this subsection we study the hydrogen atom, which is a two-body system consisting of one proton and one electron. The interaction is governed by the Coulomb potential, $$\label{CoulombPotential} V(r)=-\frac{Ze^{2}}{r}, \quad Z=1,$$ as displayed in Fig. \[PotencialCoulomb\]. Substituting the latter equation for the potential in Eq. (\[SchrodingerEnR\]) leads to $$\label{EqCoulomb} -\frac{d^{2}}{dz^{2} }R(z)+\left( \frac{l(l+1)}{z^{2}}- \frac{2}{z}-\epsilon\right) R(z)=0,\quad z=rd,$$ where the length scale $d$, has been chosen as the Bohr radius, $d=h^2/(\mu e^2)$, and $\epsilon$ stands for $\epsilon=2Ed/e^2$. We are going to solve this equation by means of an appropriate variable substitution. In order to find it we first study the asymptotic behavior of the solutions at both origin and infinity. For finite $z$ the latter equation is equivalently rewritten as $$-z \frac{d^{2}}{dz^{2}}R(z)+\left( \frac{l(l+1)}{z}- 2 - \epsilon z\right) R(z)=0,$$ while near the origin, where $R(0)=0$, and $1/z<<1/z^2$ one finds $$\left( \frac{d^{2}}{dz^{2} }- \frac{l(l+1)}{z^{2}}\right) R(z)\approx 0.$$ The latter equation can be solved by a function of the type, $R(z)=z^{t}$. This would restrict $t$ to $t=l+1$, and $t=-l$, respectively. The second solution is not acceptable because it is not finite at the origin, and we are left with the first one. Next we study the $z\rightarrow\infty$ asymptotic solution. In this case Eq. (\[EqCoulomb\]) becomes $$-\frac{d^{2}}{dz^{2}}R(z)=\epsilon R(z).$$ As long as we here are interested in the bound states, $ \epsilon < 0$, which amounts to $$\frac{d^{2}}{dz^{2}}R(z)- |\epsilon| R(z)=0.$$ The latter equation is solved by $R(z)=Ce^{\sqrt{|\epsilon |}z}$ and $R(z)=Ce^{-\sqrt{|\epsilon |}z}$. As long as we want the wave function to go to zero for large $z$, the first solution has to be dismissed. Next one changes variables in Eq. (\[EqCoulomb\]) according to $$z=f(x)=\frac{x}{\kappa }, \quad \kappa =2\sqrt{|\epsilon|}\, , \quad R\left( \frac{x}{\kappa }\right)=g(x)\, , \label{fx_Hydr}$$ where the factor $2$ has been taken for convenience. This yields $$\frac{d^{2}}{dx^{2} }g(x)+\left( - \frac{l(l+1)}{x^{2}}+\frac{1} {\sqrt{|\epsilon|} x}-\frac{1}{4}\right) g(x)=0. \label{x_factor}$$ Taking into account the correct asymptotic behavior revealed above, the solution of the latter equation can be assumed as $g(x)=x^{l+1}e^{-\frac{x}{2}}L(x)$. In result, one arrives at $$\label{EqInRs} xL''(x)+(2l+1+1-x)L'(x)+L(x)\left( \frac{1} {\sqrt{|\epsilon |}}-l-1\right) =0\,,$$ which coincides with the equation (\[Lag\_3\]) for the associated Laguerre polynomials provided $\alpha =1$, $\beta =2l+1$, and $\lambda =n$. With this in mind it is easy to verify that $$\epsilon_{nl}=-\frac{1}{(n+l+1)^{2}}.$$ Recalling the definition of ($\epsilon = 2Ed/e^2$), we obtain the spectrum as $$\label{EnergyHydAtomWithn} E_{nl}=-\frac{e^{4}\mu}{2\hbar^ {2}(n+l+1)^{2}}.$$ At that stage one defines $N=n+l+1$ as the principal quantum number, and realizes that while $n$ can be any non-negative integer, the angular momentum is restricted to a finite number of values according to $l=N-1-n$, $$l=0,1,2,..., N-1.$$ In effect, one finds the well known degeneracy patterns in the spectrum of the hydrogen atom, $E_{nl}=-\frac{e^{4}\mu}{2\hbar^{2}N^{2}}$, meaning that $\kappa $ depends on $n$. The solution for the radial equation  (\[EqInRs\]) is then concluded as $$\frac{g(x)}{x}\equiv \psi_{n l}(x)=C_{n l} x^{l}e^{-\frac{x}{2}}L^{(2l+1)}_{N-l-1}(x),$$ where use has been made of Eq. (\[DefPsi-
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tag). You’ll notice there is “Top” or “All” mode. We want to stay within Top because we want to learn about winners, not the others. Now we could use the Twitter API to programmatically download a bunch of data but we would have to sign up for access keys etc. Let’s just do it the quick and easy way for now. Start scrolling down the search page causing new results to be loaded. Just keep scrolling for a long while until you have many pages of info. Now use a quick snippet of JavaScript to grab the tweet text for processing. Pop open the JavaScript console in your browser (Cmd-Option-J in Chrome). Paste this in and press Enter: $ ( '.tweet-text' ). map ( function () { return $ . trim ( $ ( this ). text ()) ; } ). get (). join ( " " ) Revealing Patterns Select all the output and save it to a file. We’re going to extract meaning from this text. Remember that we want the essential truth contained inside so we need to remove words which would distract from or skew the essence. Save and run the following shell script on your file to remove urls, competing hash tags, and @-mentions. perl -p -i -e "s/@ \\ w+[ , \\ . \\ ? \" :']//g" $1 perl -p -i -e 's/@\w+$//g' $1 perl -p -i -e 's/#\w+[ ,\.\?":]//g' $1 perl -p -i -e 's/#\w+$//g' $1 perl -p -i -e 's/pic.twitter[^ ]+ //g' $1 perl -p -i -e 's/pic.twitter[^ ]+$//g' $1 perl -p -i -e 's/https?:[^ ]+ //g' $1 perl -p -i -e 's/https?:[^ ]+$//g' $1 We’ll use the R programming language to run topic detection through Latent Dirichlet Allocation (LDA). Here are the pieces of code to calculate them. First load the tweets, one on each line. They will each be considered small “documents” for topic detection, and are put together into a “corpus.” library (jsonlite) library (tm) tweets <- strsplit ( readLines ( '/path/to/tweets.txt' ), " " ) corp <- Corpus ( VectorSource (tweets)) To minimize inconsequential variations we will remove stop words, small words and other detritus. The remaining words are stemmed. dtm.control <- list ( tolower = TRUE , removePunctuation = TRUE , removeNumbers = TRUE , stopwords = c ( stopwords ( "SMART" ), stopwords ( "en" )), stemming = TRUE , wordLengths = c ( 3 , "inf" ), weighting = weightTf) Next we record the term occurrences per document in a sparse matrix and set up parameters. This is a “bag-of-words” approach that ignores the grammar of sentences. sparse.dtm <- DocumentTermMatrix (corp, control = dtm.control) dtm <- as.matrix (sparse.dtm) class (dtm) <- "integer" vocab <- sparse.dtm $ dimnames $ Terms # Compute some statistics related to the data set: D <- length (corp) # number of documents W <- length (vocab) # number of terms in the vocab doc.length <- rowSums (dtm) # number of tokens per document N <- sum (doc.length) # total number of tokens in the data term.frequency <- colSums (dtm) # frequencies of terms in the corpus # MCMC and model tuning parameters: K <- 20 G <- 5000 alpha <- 0.02 eta <- 0.02 Using the term frequencies we attempt to find clusters or words that tend to co-occur. This is the part that really identifies topics in tweets. # Fit the model: library (lda) lda.input <- lapply ( 1 : nrow (dtm), function (i) { docfreq <- t (dtm[i,]) keepers <- docfreq > 0 rbind ( ( 0 : ( ncol (dtm) - 1 ))[keepers], t (dtm[i,])[keepers] ) } ) fit <- lda.collapsed.gibbs.sampler ( documents = lda.input, K = K, vocab = vocab, num.iterations = G, alpha = alpha, eta = eta, initial = NULL , burnin = 0 , compute.log.likelihood = TRUE ) Finally plug the topic model into an interactive visualization that we will examine with our human intuition. theta <- t ( apply (fit $ document_sums + alpha, 2 , function (x) x / sum (x))) phi <- t ( apply ( t (fit $ topics) + eta, 2 , function (x) x / sum (x))) library (LDAvis) # create the JSON object to feed the visualization: json <- createJSON ( phi = phi, theta = theta, doc.length = doc.length, vocab = vocab, term.frequency = term.frequency) serVis (json) Time for the fun. Here’s a screenshot of the topics detected in top tweets having the #data hashtag. I have selected topic number 19 to see the frequency of the words inside. Notice I set the relevance metric slider low to focus on words that are frequent exclusively in the topic rather than frequent in the corpus as a whole. Extracting Meaning The topics can be strange. If they are too chaotic and strange it probably means the data was not sufficiently cleaned or the sample was too small. But the more you look coherent categories the more you’ll see a kind of alien logic at work picking out words with a psychological bond. At this point the algorithms have done their job and it is time for us to be creative as humans. Let me walk you through how I made sense of the topics for the #data hashtag. For each detected topic I’ll list the main word, the feelings I associate with the topic, and the other major words inside that guided my assessment. The first (TRIAL) topic is cajoling people to try data products. It emphasizes the ease and quickness, and how the solution will “unlock” things, make you smarter, and amaze your boss. storage, team, record, train, unlock, sport, free, clean, bottom, device, amazing, quick, boss, smarter Then we have the (CAPITAL) topic, all about disrupting industries and big company speculation. capital, disrupt, venture, checkout, seeker, relationship, patent, airline, google, bet, fresh, double, fund The (BITCOIN) topic deals with that currency but also with non-monetary communication communication, blah, exvers, search, speak, link, bitcoin, block, discount, listen, word, library, chain, song, teach, topic, print People worry about data, and the (BREACH) topic is full of credit cards, security compromises, and how much it costs us all. credit, hit, compromise, driver, uber, interpret, human, card, replace, commission, hardware, neutral, pool, cost Of course you can’t have #data without (BIG). Apparently we’re “drowning” in it and it’s a veritable “lake,” but “wow” it is so big. industry, lake, reach, love, move, drown, session, loyalty, wow The (OPPORTUNITY) topic deals with vision and red-hot engineers in the valley. You can not only wrangle data, you can be a data king. location-based, senior, apply, hadoop, develop, succeed, hire, engineer, need, wrangle, vision, creator, gather, king, cluster, kingdom, hot, always, valley, red Then we have (BRANDS) and their associated trust words. People want to rate them and make decisions. rate, trust, begin, smart, comfort, brain, decision, healthcare, focus, true, specific, rapid, crime, machine, vital, care, attribute, past, player, influence, patient Whereas opportunity was about creative struggle and power, (ADVANTAGE) is more about reassurance. A.k.a. debunking myths, providing answers, and strategizing. advertis, myth, valuable, password, fuel, answer, data-driven, tip, like, competitive, autom, raw, break, provid, deliv, strategi, integr, analysi, format Beyond the technical aspects we have (LEGAL) implications. Laws passed or killed, policities about encryption and telecommunications. phone, law, talktalk, combine, benefit, energi, save, stolen, plan, summari, encrypt, communicate, kill, pass, appeal, backup, transit, fall, bus, attack Observation Two Topics generated by LDA reveal strange, sometimes psychological connections in tweets. Is this subjective? Very much so. But I am searching for archetypal tweet structures, and some topics can be fairly conclusive. I have run this process
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far as the burden of transportation is concerned, and to be denied so far as any benefits from such transportation are sought. The framers of the Constitution never intended that a right given should not be fully enjoyed. In Brown v. Maryland, 12 Wheat. 419, 446, Chief Justice Marshall, in delivering the opinion of the court, speaking of the commercial power of Congress, and after observing that it is co-extensive with the subject on which it acts, and cannot be stopped at the exterior boundary of a State, but must enter its interior, said: "If this power reaches the interior of a State, and may be there exercised, it must be capable of authorizing the sale of those articles which it introduces. Commerce is intercourse; — one of its most ordinary ingredients is traffic. It is inconceivable that the power to authorize this traffic, when given in the most comprehensive terms, with the intent that its efficacy should be complete, should cease at the point when its continuance is indispensable to its value. To what purpose should the power to allow importation be given, unaccompanied with the power to authorize a sale of the thing imported? Sale is the object of importation, and is an essential ingredient of that intercourse of which importation constitutes a part. It is as essential an ingredient, as indispensable to the existence of the entire thing, then, as importation itself. It must be considered as a component part of the power to regulate commerce. Congress has a right, not only to authorize importation, but to authorize the importer to sell... . The power claimed by the State is, in its nature, in conflict with that given to Congress; and the greater or less extent in which it may be exercised does not enter into the inquiry concerning its existence. We think, then, that if the power to authorize a sale exists in Congress, the conclusion that the right to sell is connected with the law permitting importation, as an inseparable incident, is inevitable." And the Chief Justice added: "We suppose the principles laid down in this case to apply equally to importations from a sister State." p. 449. Assuming, therefore, as correct doctrine that the right of importation carries the right to sell the article imported, the *506 decision in the Kansas case may perhaps be reconciled with the one in this case by distinguishing the power of the State over property created within it, and its power over property imported — its power in one case extending, for the protection of the health, morals, and safety of its people, to the absolute prohibition of the sale or use of the article, and in the other extending only to such regulations as may be necessary for the safety of the community until it has been incorporated into and become a part of the general property of the State. However much this distinction may be open to criticism, it furnishes, as it seems to me, the only way in which the two decisions can be reconciled. There is great difficulty in drawing the line precisely where the commercial power of Congress ends and the power of the State begins. The same difficulty was experienced in Brown v. Maryland, in drawing a line between the restriction on the States to lay a duty on imports and their acknowledged power to tax persons and property. In that case the court said that the two, the power and the restriction, though distinguishable when they did not approach each other, might, like the intervening colors between white and black, approach so nearly as to perplex the understanding as colors perplex the vision, in marking the distinction between them: but as the distinction existed, it must be marked as the cases arise. And after observing that it might be premature to state any rule as being universal in its application, the court held as sufficient for that case that when the importer had so acted upon the thing imported, that it had become incorporated and mixed up with the mass of property in the country, it had lost its distinctive character as an import, and had become subject to the taxing power of the state; but that while remaining the property of the importer, in his warehouse in the original form or package in which it was imported, a tax upon it was plainly a duty on imports. So in the present case it is perhaps impossible to state any rule which would determine in all cases where the right to sell an imported article under the commercial power of the Federal government ends and the power of the state to restrict *507 further sale has commenced. Perhaps no safer rule can be adopted than the one laid down in Brown v. Maryland, that the commercial power continues until the articles imported have become mingled with and incorporated into the general property of the State, and not afterwards. And yet it is evident that the value of the importation will be materially affected, if the article imported ceases to be under the protection of the commercial power upon its sale by the importer. There will be little inducement for one to purchase from the importer, if immediately afterwards he can himself be restrained from selling the article imported; and yet the power of the State must attach when the imported article has become mingled with the general property within its limits, or its entire independence in the regulation of its internal affairs must be abandoned. The difficulty and embarrassment which may follow must be met as each case arises. In The License Cases, reported in 5 Howard, this court held that the States could not only regulate the sales of imported liquors, but could prohibit their sale. The judges differed in their views in some particulars, but the majority were of opinion that the States had authority to legislate upon subjects of interstate commerce until Congress had acted upon them; and as Congress had not acted, the regulation of the States was valid. The doctrine thus declared has been modified since by repeated decisions. The doctrine now firmly established is, that where the subject upon which Congress can act under its commercial power is local in its nature or sphere of operation, such as harbor pilotage, the improvement of harbors, the establishment of beacons and buoys to guide vessels in and out of port, the construction of bridges over navigable rivers, the erection of wharves, piers, and docks, and the like, which can be properly regulated only by special provisions adapted to their localities, the State can act until Congress interferes and supersedes its authority; but where the subject is national in its character, and admits and requires uniformity of regulation, affecting alike all the States, such as transportation between the States, including the importation of goods from one State into another, Congress can alone act upon it and provide the *508 needed regulations. The absence of any law of Congress on the subject is equivalent to its declaration that commerce in that matter shall be free. Thus the absence of regulations as to interstate commerce with reference to any particular subject is taken as a declaration that the importation of that article into the States shall be unrestricted. It is only after the importation is completed, and the property imported has mingled with and become a part of the general property of the State, that its regulations can act upon it, except so far as may be necessary to insure safety in the disposition of the import until thus mingled. Cooley v. Board of Wardens of the Port of Philadelphia, 12 How. 299, 319; State Freight Tax Case, 15 Wall. 232, 271; Welton v. Missouri, 91 U.S. 275, 282; Railroad Co. v. Husen, 95 U.S. 465, 469; Mobile v. Kimball, 102 U.S. 691, 697; Gloucester Ferry Co. v. Pennsylvania, 114 U.S. 196, 203; Brown v. Houston, 114 U.S. 622, 631; Walling v. Michigan, 116 U.S. 446, 455; Pickard v. Pullman Southern Car Co., 117 U.S. 34; Wabash &c. Railway Co. v. Illinois, 118 U.S. 557; Robbins v. Shelby County Taxing District, 120 U.S. 489. It is a matter of history that one of the great objects of the formation of the Constitution was to secure uniformity of commercial regulations, and thus put an end to restrictive and hostile discriminations by one State against the products of other States, and against their importation and sale. "It may be doubted," says Chief Justice Marshall, "whether any of the evils proceeding from the feebleness of the Federal government contributed more to that great revolution which introduced the present system than the deep and general conviction that commerce ought to be regulated by Congress. It is not, therefore, matter of surprise that the grant should be as extensive as the mischief, and should comprehend all foreign commerce and all commerce among the States. To construe the power so as to impair its efficacy would tend to defeat an object, in the attainment of which the American government took, and justly took, that strong interest which arose from a full conviction of its necessity." Brown v. Maryland, 12 Wheat. 446. To these views I may add, that if the States *509 have the power asserted, to exclude from importation within their limits any articles of commerce because in their judgment the articles may be injurious to their interests or policy, they may prescribe conditions upon which such importation will be admitted, and thus establish a system of duties as hostile to free commerce among the states as any that existed previous to the adoption of the Constitution. MR. JUSTICE HARLAN, with whom concurred THE CHIEF JUSTICE, and MR. JUSTICE GRAY, dissenting. The Chief Justice, Mr. Justice Gray, and myself are unable to assent to the opinion and judgment of the court. The effect of the statutes of Iowa is to forbid the introduction of intoxicating liquors from other States for sale, except for medicinal, mechanical, culinary, or sacramental purposes. They may be brought in for such purposes, by any person, or carrier, for another
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ää nykyisen epätyydyttävän tilanteen tarpeettoman jatkamisen. Parlamentin mietinnössä esittelijä käsittelee joitakin ehdotuksiaan parannuksiksi, jotka voisi tai pitäisi sisällyttää tulevaan ehdotukseen uudeksi asetukseksi. Komission pitäisi ottaa nämä ehdotukset huomioon ja esittää viipymättä uutta ja parempaa ehdotusta. Luís Paulo Alves Äänestän tämän mietinnön puolesta, koska Yhdysvaltojen ja EU:n yhteisten ilmailumarkkinoiden osuus on noin 60 prosenttia maailman lentoliikenteestä, ja nykyiset kahdenväliset sopimukset jäsenvaltioiden ja Yhdysvaltojen välillä eivät vastaa todellisuutta. Ilmailumarkkinoiden avaaminen Yhdysvaltojen ja EU:n välillä syrjimättömyyden pohjalta tarjoaisi matkustajille ja rahtiliikenteen harjoittajille parempia palveluja, taloudellisia etuja ja ennen kaikkea työpaikkoja. Sanoisin siksi, että tämä on hyödyllistä, koska sääntelyn lähentäminen voisi edistää vapaata kilpailua erityisesti valtiontukien sekä sosiaali- ja ympäristönormien osalta. Sophie Auconie Yhdysvaltojen ja EU:n ilmailumarkkinoiden osuus on yli puolet maailman lentoliikenteestä. Ilmaston lämpenemisen takia Euroopan unionin ja Yhdysvaltojen on siksi tehtävä yhteistyötä vähentääkseen kansainvälisen ilmailun ympäristövaikutusta. Olen siksi äänestänyt sopimuksen puolesta, koska siinä molemmat osapuolet sitoutuvat hyväksymään ympäristö- ja sosiaalinormit, joilla vähennetään huomattavasti melusaastetta ja lievennetään ilmaliikenteen päästöjen vaikutuksia ilmanlaatuun ja samalla kuitenkin myös sitoudutaan kehittämään kestäviä vaihtoehtoisia polttoaineita. Ensimmäisen kerran molemmat osapuolet ovat sopineet takaavansa lentohenkilökunnan sosiaaliset oikeudet. Zigmantas Balčytis kirjallinen. - (LT) Olen samaa mieltä tästä pöytäkirjasta EU:n ja Yhdysvaltojen välisen lentoliikennesopimuksen muuttamisesta. Pöytäkirjassa on merkittäviä osia, joiden nojalla EU:n ja Yhdysvaltojen yhteistyö ilmailuasioissa voi edetä. Siinä myös vältetään riski, että mikäli kyseistä sopimusta ei ole, joku voisi alkaa soveltaa lykkäysehtoa, joka on ensimmäisen vaiheen sopimuksessa. Lykkäys voisi johtaa siihen, että eurooppalaiset matkustajat ja lentoyhtiöt menettävät huomattavia etuja, joista ne ovat nauttineet maaliskuusta 2008 lähtien. Huomiota olisi kiinnitettävä myös siihen, että tämä uusi sopimus avasi mahdollisuudet tuleville lisäinvestoinneille ja markkinapääsylle sekä yhteistyön tiivistämiselle esimerkiksi turvallisuutta, varmuutta ja varsinkin ympäristöä koskevilla sääntelyn alueilla, ja osapuolet sopivat erityisestä ympäristöalan yhteisestä julistuksesta. Adam Bielan EU:n jäsenvaltioiden ja Yhdysvaltojen osuus maailman ilmailumarkkinoista on 60 prosenttia. Meidän pitäisi siksi pyrkiä varmistamaan vakaa palvelujen laadun paraneminen tällä alalla. Sopimalla EU:n ja Yhdysvaltojen välisen lentoliikennesopimuksen tekemisestä edistämme ilmailualan kasvua mahdollistamalla suurempien investointien houkuttelemisen molemmilla puolilla Atlanttia. Sopimuksella autetaan myös vahvistamaan alan työntekijöiden oikeuksien suojaa, lisäämään yhteistyötä lentomatkustuksen turvallisuuden osalta ja myös, yhteensopivuusvaatimuksen ansiosta, vahvistamaan yhteistyötä ympäristöasioissa. On myös merkittävää, että EU:n ja Yhdysvaltojen sekakomitean asemaa vahvistetaan sallimalla sen edistää uusia aloitteita, kun sopimusta pannaan täytäntöön. Minun mielestäni uudella sopimuksella autetaan avaamaan lisää markkinoillepääsyä, mikä tarkoittaa aiempaa laadukkaampia palveluja ja ankarampia turvallisuusvaatimuksia, ja siksi tuen päätöslauselmaa. Izaskun Bilbao Barandica kirjallinen. - (ES) Äänestin tämän aloitteen puolesta, koska ilmailumarkkinoiden osuus on 60 prosenttia maailman liikenteestä. Tällä sopimuksella tuodaan Yhdysvaltojen lainsäädäntöön muutoksia, jotka ovat välttämättömiä sääntelyn lähentämisen lisäämiseksi epäoikeudenmukaisen kilpailun estämiseksi. Uusia reittejä avataan, ja liikenteenharjoittajille ja matkustajille tarjotaan parempia palveluja ja hintoja, jotka puolestaan edistävät talouskasvua ja johtavat työpaikkojen luomiseen Atlantin molemmilla puolilla. Sebastian Valentin Bodu Vaikka EU:n ja Yhdysvaltojen lentoliikennesopimus on kaikkea muuta kuin täydellinen, se on edistysaskel, joka avaa sekä uusia mahdollisuuksia lisäinvestointien ja markkinoillepääsyn osalta että myös paremman turvallisuuden ja varmuuden osalta. Kumpikaan osapuoli ei ole täysin avannut lentoliikennemarkkinoita neuvotteluissa saavutetun sopimuksen version tuloksena. Siinä on kuitenkin riittävästi kannustimia uudistuksen edistämiseksi. Yhdysvaltojen on muutettava kansallista lainsäädäntöään salliakseen EU:n investoijille enemmistöosuuden Yhdysvaltojen lentoyhtiöissä, mikä edellyttää vastavuoroisia toimenpiteitä EU:lta. EU:n ja Yhdysvaltojen sekakomitea on saanut lisää valtuuksia, mikä tarkoittaa, että se pystyy edistämään yhteistyötä edistämällä uusia aloitteita. Uusilla säännöillä vähennetään byrokratiaa, myös kunkin osapuolen sääntelypäätösten vastavuoroisella tunnustamisella, ja vältetään tuhlailevaa resurssien päällekkäisyyttä. Sosiaalisen ulottuvuuden merkityksen tunnustaminen ja sekakomitealle annettu vastuu valvoa sopimuksen sosiaalisia vaikutuksia ja kehittää asianmukaisia vastauksia tarvittaessa ovat sopimuksen toisessa vaiheessa esitet
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करूंगा। बिल्कुल सही हाँ, यह वास्तव में एक अच्छा दिन है। जैसे मैं इसके साथ वास्तव में खुश हूँ लेकिन हाँ, मेरा मतलब है टीमों ने स्पष्ट रूप से बहुत से टीम टूल्स का इस्तेमाल किया क्या आप और वॉल स्ट्रीट जर्नल लोग प्रोजेक्ट मैनेजर या ऐसा कुछ भी इस्तेमाल करते हैं? क्या आप बस अपने निजी कार्यों की तरह चिपके रहेंगे और जवाबदेही, मुझे लगता है कि यह दोनों का मिश्रण है। हम बहुत से ईमेल का उपयोग करते हैं हम बहुत सारी Google चादरें करते हैं जो लड़का मुझे नफरत है और मैं ईमानदारी से, उम्मीद है कि मेरे मालिक इस बात को सुनें और Google शीट्स का उपयोग करने के बारे में अपने दिमाग को बदल दें, लेकिन हम हाँ का उपयोग करते हैं, मेरा मतलब है यह ज्यादातर Google सामान सिर्फ इसलिए है क्योंकि यह है Arabic: وهذا هو مثل ما لا تستخدمه بعد الآن بسبب القصور الذاتي. أنا لا أستخدم Evernote بعد الآن لكن استخدامي الواضح تقلص إلى النصف في الأشهر الستة الأخيرة من هذا القبيل. أنا فقط أحب الخروج فقط في مفهومها. سأضيفها فقط في فكرة بدلاً من أن أبدأها في Evernote. صح نعم ، إنه يوم جيد حقا. مثل أنا حقا سعيد به لكن نعم ، أعني من الواضح أن الفرق كانت تستخدم الكثير من أدوات الفريق هل تستخدم أنت ورجال وول ستريت جورنال مثل مدير المشروع أو أي شيء من هذا القبيل؟ هل ستلتزم فقط بمثل المهام الشخصية الخاصة بك و المساءلة ، أعتقد أنه مزيج من الاثنين. نحن نستخدم الكثير من رسائل البريد الإلكتروني نقوم بالكثير من أوراق Google أي صبي أكره وأنا بصدق ، آمل أن يستمع رؤسائي لهذا الأمر وأن يغيروا رأيهم حول استخدام أوراق Google ، ولكن نحن نستخدم نعم ، أعني انها في الغالب جوجل الاشياء فقط لأنه German: Das sind sozusagen die geteilten Apps und besonders bei einer Organisation, die so groß ist wie die, für die ich neue Software einführe Ein größeres Level ist nur, es ist eine Menge Arbeit und so sind wir relativ Stabil in den Dingen, die funktionieren, und nicht versuchen, das zu zerstören Aber ich mag es, meine eigenen Sachen getrennt zu haben. Es ist ein bisschen wie ein Duplikat von Arbeit Ich muss sicherstellen, dass die Google-Tabellen mit all den Dingen aktualisiert werden, die ich auch mache, aber dazu in der Lage bin Irgendwie haben sie seltsame Notizen, die für niemanden Sinn machen und Schimpfwörter schreiben Und ich weiß nicht, nur einen Platz haben. Das gehört mir Das ist nicht nur ein Tab in einer Sache, die jemand anderes sehen kann, sondern ist ganz mein Eigen Es ist wirklich sehr nett und ich weiß nicht, dass ich das ändern würde, selbst wenn ich könnte Brilliant und eine letzte Art von runden Frage Offensichtlich ist dein Tag manisch, als ob du in der Lage wärst, über all den Tech-Nachrichten auf dem Laufenden zu bleiben, wie es schön sein muss Stressig wie nehmen Sie sich Zeit? French: Ce sont en quelque sorte les applications partagées et en particulier dans une organisation aussi grande que celle dans laquelle je travaille pour introduire de nouveaux logiciels à un plus grand niveau est juste que c'est beaucoup de travail et nous sommes relativement Stable dans les choses qui fonctionnent et n'essayent pas de faire sauter ça Mais j'aime bien avoir mes propres affaires séparées. C'est un peu une sorte de duplicata de travail Je dois faire en sorte que les feuilles de Google soient mises à jour avec tout ce que je fais, mais je suis capable de Sorte de notes bizarres qui n'auront aucun sens pour les autres et aiment écrire des mots grossiers Et je ne sais pas juste avoir un espace. C'est en quelque sorte le mien Ce n'est pas juste comme un onglet dans une chose que quelqu'un d'autre peut voir mais est entièrement le mien C'est en fait vraiment sympa et je ne sais pas que je changerais ça même si je pouvais Brilliant et une dernière sorte de question d'arrondi De toute évidence, votre journée est maniaque comme être capable de rester au fait de toutes les nouvelles technologiques comme si elles devaient être belles. Stressant, comment est-ce que vous prenez le temps de faire une pause? Hindi: वे साझा किए गए ऐप्स की तरह हैं और विशेष रूप से एक संगठन में जितना बड़ा मैं किसी नए सॉफ्टवेयर को पेश करने के लिए काम करता हूं एक बड़ा स्तर यह है कि यह बहुत काम है और इसलिए ह
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Healer, Sympathy, Quality, Sustenance, Unconditional love, Charity, Balance, Grace, Evolution Adrestus=1+4+9+5+1+2+3+1= 26= 8 Chinese dragon : Huanglong - the Yellow Dragon Chinese [ Pinyin ] : Qi1 and Japan [ Hachi - ya(ttsu) ] I-Ching [ ancient ] : #26 Ta ch'u I-Ching [ revised ] : whole + double divisible Feng Shui number : Wealth - Abundance Feng Shui House number: Multiply - fertile Interpretation : Wealth, Power, Riches, Status, Material, Pragmatism, Aggregation, Dictatorship, Business, Investment, Skills, Reality Adria=1+4+9+9+1= 24= 6 Chinese dragon : Jiaolong - the Horned Dragon Chinese [ Pinyin ] : Wu3 and Japan [ Roku - pyn(ttsu) ] I-Ching [ ancient ] : Sung I-Ching [ revised ] : whole + whole Feng Shui number : Esthetics - Beauty Feng Shui House number: Wealth Interpretation : Protector, Provider, Healer, Sympathy, Quality, Sustenance, Unconditional love, Charity, Balance, Grace, Evolution Adriaen=1+4+9+9+1+5+5= 34= 7 Chinese dragon : Panlong - the Coiling Dragon Chinese [ Pinyin ] : Liu4 and Japan [ Shichi - nana(tsu) ] I-Ching [ ancient ] : #52 Ken I-Ching [ revised ] : divisible + whole Feng Shui number : Mystical Yin Feng Shui House number: Sure Interpretation : Thinker, Science, Learning, Education, Study, Logic, Alchemy, Secrets, Myth, Religion, Ritual, Knowledge, Dignity, Genius Adriaens=1+4+9+9+1+5+5+1= 35= 8 Chinese dragon : Huanglong - the Yellow Dragon Chinese [ Pinyin ] : Qi1 and Japan [ Hachi - ya(ttsu) ] I-Ching [ ancient ] : #26 Ta ch'u I-Ching [ revised ] : whole + double divisible Feng Shui number : Wealth - Abundance Feng Shui House number: Multiply - fertile Interpretation : Wealth, Power, Riches, Status, Material, Pragmatism, Aggregation, Dictatorship, Business, Investment, Skills, Reality Adrial=1+4+9+9+1+3= 27= 9 Chinese dragon : Dragon King Chinese [ Pinyin ] : Ba1 and Japan [ Kyu, ku - kokono(tsu) ] I-Ching [ ancient ] : #20 Kuan I-Ching [ revised ] : double divisible + divisible Feng Shui number : Completion - Manifestation Feng Shui House number: Longevity Interpretation : Humanitarian, Religious, Charitable, Philanthropic, Higher Self, Spirit Guides, Mysticism, Faith, Optimist, Karma, Enlightenment Adrian=1+4+9+9+1+5= 29= 2 Chinese dragon : Shenlong - the Spiritual Dragon Chinese [ Pinyin ] : Yi1 and Japan [ Ni, ji - futa(tsu) ] I-Ching [ ancient ] : K'un I-Ching [ revised ] : double divisible + whole Feng Shui number : Promotes relationship Feng Shui House number: Sure Interpretation : Cooperation, Consideration, Balance, Mediation, Flexibility, Adaptability, Grace, Dance, Harmony, Devotion Adriana=1+4+9+9+1+5+1= 30= 3 Chinese dragon : Fucanglong - the Dragon of Hidden Treasures Chinese [ Pinyin ] : Er4 and Japan [ San - mi(ttsu) ] I-Ching [ ancient ] : Pi I-Ching [ revised ] : divisible double + divisible Feng Shui number : Creation - father and mother yield a child Feng Shui House number: Growth – alive Interpretation : Holy Trinity, Faith, Expression, Speech, Society, Art, Culture, Sensuality, Sorrow, Immaturity, Passion, Sex Adriane=1+4+9+9+1+5+5= 34= 7 Chinese dragon : Panlong - the Coiling Dragon Chinese [ Pinyin ] : Liu4 and Japan [ Shichi - nana(tsu) ] I-Ching [ ancient ] : #52 Ken I-Ching [ revised ] : divisible + whole Feng Shui number : Mystical Yin Feng Shui House number: Sure Interpretation : Thinker, Science, Learning, Education, Study, Logic, Alchemy, Secrets, Myth, Religion, Ritual, Knowledge, Dignity, Genius Adrianna=1+4+9+9+1+5+5+1= 35= 8 Chinese dragon : Huanglong - the Yellow Dragon Chinese [ Pinyin ] : Qi1 and Japan [ Hachi - ya(ttsu) ] I-Ching [ ancient ] : #26 Ta ch'u I-Ching [ revised ] : whole + double divisible Feng Shui number : Wealth - Abundance Feng Shui House number: Multiply - fertile Interpretation : Wealth, Power, Riches, Status, Material, Pragmatism, Aggregation, Dictatorship, Business, Investment, Skills, Reality Adrianne=1+4+9+9+1+5+5+5= 39= 3 Chinese dragon : Fucanglong - the Dragon of Hidden Treasures Chinese [ Pinyin ] : Er4 and Japan [ San - mi(ttsu) ] I-Ching [ ancient ] : Pi I-Ching [ revised ] : divisible double + divisible Feng Shui number : Creation - father and mother yield a child Feng Shui House number: Growth – alive Interpretation : Holy Trinity, Faith, Expression, Speech, Society, Art, Culture, Sensuality, Sorrow, Immaturity, Passion, Sex Adriano=1+4+9+9+1+5+6= 35= 8 Chinese dragon : Huanglong - the Yellow Dragon Chinese [ Pinyin ] : Qi1 and Japan [ Hachi - ya(ttsu) ] I-Ching [ ancient ] : #26 Ta ch'u I-Ching [ revised ] : whole + double divisible Feng Shui number : Wealth - Abundance Feng Shui House number: Multiply - fertile Interpretation : Wealth, Power, Riches, Status, Material, Pragmatism, Aggregation, Dictatorship, Business, Investment, Skills, Reality Adrianople=1+4+9+9+1+5+6+7+3+5= 50= 5 Chinese dragon : Yinglong - the Winged Dragon Chinese [ Pinyin ] : Si4 and Japan [ Go - itsu(tsu) ] I-Ching [ ancient ] : #15 Ch'ien I-Ching [ revised ] : divisible + divisible Feng Shui number : Change Feng Shui House number: Balance Interpretation : Visionary, Expansion, Opportunity, Adventure, Imagination, Story-telling, Symbols, Freedom, Healing, Invention Adrianopolis=1+4+9+9+1+5+6+7+6+3+9+1= 61= 7 Chinese dragon : Panlong - the Coiling Dragon Chinese [ Pinyin ] : Liu4 and Japan [ Shichi - nana(tsu) ] I-Ching [ ancient ] : #52 Ken I-Ching [ revised ] : divisible + whole Feng Shui number : Mystical Yin Feng Shui House number: Sure Interpretation : Thinker, Science, Learning, Education, Study, Logic, Alchemy, Secrets, Myth, Religion, Ritual, Knowledge, Dignity, Genius Adriatic=1+4+9+9+1+2+9+3= 38= 2 Chinese dragon : Shenlong - the Spiritual Dragon Chinese [ Pinyin ] : Yi1 and Japan [ Ni, ji - futa(tsu) ]
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800001d8: 143022f3 csrr t0,stval 800001dc: 10513823 sd t0,272(sp) 800001e0: 142022f3 csrr t0,scause 800001e4: 10513c23 sd t0,280(sp) 800001e8: 00010513 mv a0,sp 800001ec: 3a40206f j 80002590 <handle_trap> Disassembly of section .text: 0000000080002000 <memcpy>: 80002000: 00c5e7b3 or a5,a1,a2 80002004: 00f567b3 or a5,a0,a5 80002008: 0077f793 andi a5,a5,7 8000200c: 00c506b3 add a3,a0,a2 80002010: 02078463 beqz a5,80002038 <memcpy+0x38> 80002014: 00c58633 add a2,a1,a2 80002018: 00050793 mv a5,a0 8000201c: 02d57e63 bgeu a0,a3,80002058 <memcpy+0x58> 80002020: 0005c703 lbu a4,0(a1) 80002024: 00158593 addi a1,a1,1 80002028: 00178793 addi a5,a5,1 8000202c: fee78fa3 sb a4,-1(a5) 80002030: fec598e3 bne a1,a2,80002020 <memcpy+0x20> 80002034: 00008067 ret 80002038: fed57ee3 bgeu a0,a3,80002034 <memcpy+0x34> 8000203c: 00050793 mv a5,a0 80002040: 0005b703 ld a4,0(a1) 80002044: 00878793 addi a5,a5,8 80002048: 00858593 addi a1,a1,8 8000204c: fee7bc23 sd a4,-8(a5) 80002050: fed7e8e3 bltu a5,a3,80002040 <memcpy+0x40> 80002054: 00008067 ret 80002058: 00008067 ret 000000008000205c <memset>: 8000205c: 00c567b3 or a5,a0,a2 80002060: 0077f793 andi a5,a5,7 80002064: 00c50633 add a2,a0,a2 80002068: 0ff5f593 andi a1,a1,255 8000206c: 00078e63 beqz a5,80002088 <memset+0x2c> 80002070: 00050793 mv a5,a0 80002074: 04c57263 bgeu a0,a2,800020b8 <memset+0x5c> 80002078: 00178793 addi a5,a5,1 8000207c: feb78fa3 sb a1,-1(a5) 80002080: fef61ce3 bne a2,a5,80002078 <memset+0x1c> 80002084: 00008067 ret 80002088: 00859793 slli a5,a1,0x8 8000208c: 00b7e5b3 or a1,a5,a1 80002090: 01059793 slli a5,a1,0x10 80002094: 00b7e7b3 or a5,a5,a1 80002098: 02079593 slli a1,a5,0x20 8000209c: 00f5e5b3 or a1,a1,a5 800020a0: fec572e3 bgeu a0,a2,80002084 <memset+0x28> 800020a4: 00050793 mv a5,a0 800020a8: 00878793 addi a5,a5,8 800020ac: feb7bc23 sd a1,-8(a5) 800020b0: fec7ece3 bltu a5,a2,800020a8 <memset+0x4c> 800020b4: 00008067 ret 800020b8: 00008067 ret 00000000800020bc <strlen>: 800020bc: 00054783 lbu a5,0(a0) 800020c0: 00078e63 beqz a5,800020dc <strlen+0x20> 800020c4: 00050793 mv a5,a0 800020c8: 0017c703 lbu a4,1(a5) 800020cc: 00178793 addi a5,a5,1 800020d0: fe071ce3 bnez a4,800020c8 <strlen+0xc> 800020d4: 40a78533 sub a0,a5,a0 800020d8: 00008067 ret 800020dc: 00000513 li a0,0 800020e0: 00008067 ret 00000000800020e4 <strcmp>: 800020e4: 00054783 lbu a5,0(a0) 800020e8: 00158593 addi a1,a1,1 800020ec: 00150513 addi a0,a0,1 800020f0: fff5c703 lbu a4,-1(a1) 800020f4: 00078a63 beqz a5,80002108 <strcmp+0x24> 800020f8: fee786e3 beq a5,a4,800020e4 <strcmp> 800020fc: 0007851b sext.w a0,a5 80002100: 40e5053b subw a0,a0,a4 80002104: 00008067 ret 80002108: 00000513 li a0,0 8000210c: ff5ff06f j 80002100 <strcmp+0x1c> 0000000080002110 <memcmp>: 80002110: 00b567b3 or a5,a0,a1 80002114: 0077f793 andi a5,a5,7 80002118: 02079e63 bnez a5,80002154 <memcmp+0x44> 8000211c: ff867813 andi a6,a2,-8 80002120: 01050833 add a6,a0,a6 80002124: 03057863 bgeu a0,a6,80002154 <memcmp+0x44> 80002128: 00050793 mv a5,a0 8000212c: 0100006f j 8000213c <memcmp+0x2c> 80002130: 00878793 addi a5,a5,8 80002134: 00858593 addi a1,a1,8 80002
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end your Detox phase to fourteen days (instead of seven) if one or more of these describe you: — You have fifty pounds or more to lose — You currently drink alcoholic beverages three or more times per week — You are a smoker • You extend your Detox phase because, under these conditions, it may take longer than seven days to detox and prepare your body for the Ignite phase. This extended detox will help maximize your body's fat-burning ability. Three Steps to Detox: Cut, Clean, Flush Your Detox phase loses your bloat as easy as 1, 2, 3: Step 1: Cut Step 2: Clean Step 3: Flush You cut the foods that bloat you, you add the clean foods to cleanse, and you flush the toxins with H2O. #### _Step 1: Cut_ Detoxing is all about cleaning out your system. Imagine getting an oil change for your car but only adding new oil and still using your old, dirty, and used-up oil filter. As fresh and high quality as that new oil is, it still will be processed through that old filter. This means your car's engine is still getting a lot of grime and grit from the old filter and losing the benefit of the new oil so it won't run as well as it could be running. This concept parallels perfectly with your body. Eating cleaner without detoxing is just like getting an oil change without changing your filter. It only solves part of the problem, so to maximize the cleaner foods you're eating, you also need to clean up your body's filters by removing all the gunk, which will get your metabolism running like a well-oiled machine! As you detox, you'll also be losing excess bloat. Bloating slows down the speed of your metabolism, inflates your weight, and makes your clothes feel a size too small. It's time to get you comfortably fitting back into your pre-baby jeans (this is true for both men and women) and lose that muffin top, aka love handles. To do that, your first step is to cut the foods and drinks that cause bloating. Below is a list of foods that make you retain water, followed by a short explanation as to why each food or drink should be removed in this phase. * * * Quick Tip * * * Before you start cursing me, I promise that after your 8 Week Run, you'll be able to bring these foods moderately back into your meal plan if you so desire, during your Thrive phase, and a few during your Ignite phase. Foods to Cut During Your Detox Phase #### _Gluten_ Gluten is a hot topic and is quickly being recognized as one of the biggest bloating and inflammatory ingredients in foods. Gluten is a complex protein that gives bread its elasticity and is extremely hard for your body to digest. It's typically found in most bread products, pastas, and cereals. This difficulty with digestion is what leads to inflammation and bloating. Look for gluten-free labels. #### _Soy_ Soybeans contain organic compounds called isoflavones. These compounds trigger your body to produce the hormone estrogen, and estrogen causes your body to store fat and bloat. Estrogen is an important hormone in women and men (that's right—men have a little estrogen too!). The challenge with estrogen is when your body produces too much, which is exactly why soy is cut in your Detox phase—to prevent estrogen overload! #### _Cheeses and Yogurt_ I know this might be a tough one, as cheese and yogurt are easy grab 'n' go proteins and they taste great. But both of these introduce two challenges. First, they are loaded with lactose (a sugar found in dairy). To efficiently digest lactose, your body produces an enzyme called lactase. When you don't have enough lactase, lactose can't be fully digested, causing bloating and gas (always fun!). The second challenge is that many people have a slight allergy to milk protein. The result can be excess mucus, which leads to head and chest congestion as well as inflammation. Now you might be thinking, _Where will I be getting my calcium?_ Simple, add green leafy vegetables like spinach, kale, and collard greens and green vegetables like broccoli and asparagus to your plan. They are loaded with calcium and don't cause bloating. * * * Exception * * * In step 2 of your Detox phase, Clean (your next step), I explain why it's important to have shakes as well as whole food in your meal plan. Two of the recommended shakes in your plan do contain some milk protein, Core Protein made by MYNT and Proto Whey made by Power Crunch. Due to the way both of these shakes are made, you shouldn't experience any digestive challenges that you might encounter with whole-milk protein like cheese and yogurt. If you still experience digestive challenges, simply switch to egg-white protein or one of the recommended plant-based protein powders. #### _Refined Sugar_ We often hear, "Avoid sugar." That statement doesn't make much sense since all carbohydrates (fruit, vegetables, and grains, with fiber being the exception) are metabolized into sugar. What you actually need to watch for is refined sugar, which is the added sugar that's found in candy, soda, most processed foods, and so on. Refined sugars include basically any sugar that's not naturally occurring in the food. These types of sugars spike your blood sugar, which triggers fat storage and water retention. #### _Sugar-Free Sweeteners_ Ever have gas when chewing sugar-free gum? It happens to most of us, and the culprit is the sugar-free sweetener in the gum. The most used sugar-free sweeteners include: aspartame, saccharine, sorbitol, xylitol, and sucralose. These are "fake" sugars that are formed with a double sugar molecule that your body can't digest. Since this molecule can't be digested, the result is gas and bloating. There is plenty of research that these once-touted calorie savers may actually be worse for your body than refined sugar is. The great news is, there is already a natural and healthy sweetener on the market called stevia, which can be digested by your body. #### _Salt_ I remember watching my mom have some popcorn with her salt, seriously! And the next day she would share how puffy she felt. Adding salt to your food or eating processed food (which is loaded with salt) will cause massive bloating. Every milligram of sodium attracts water, causing your body to retain water. The more salt you eat, the more bloating you'll experience. In your Detox phase, the only salt you will have is the small natural amount in the clean foods you'll be eating. If you're a salt lover like my mom, no need to panic, in your Thrive phase, you can moderately add salt back into your plan. Your two best salt choices are sea salt and pink Himalayan salt, as both are natural and unprocessed and help minimize the bloating effects of regular table salt. Just remember to use them moderately. #### _Soda/Pop (Diet and Regular)_ I know this isn't a shocker, as we're told by almost everyone to cut soda. There's a good reason to do this. All types of sodas are full of chemicals, carbonation (which causes gas in your intestines), and either refined sugar (regular soda) or sugar-free sweeteners (diet soda). What I've learned is people are attached to their soda, so I'm simply asking you to cut it for seven days. What you'll see is that seven days later, you won't crave soda anymore and you'll be less bloated. Double win! #### _Alcohol_ Now you might be thinking, _I thought alcohol dehydrates me, so how can it bloat me?_ Well you're right that it dehydrates you. When your body feels it doesn't have enough water, it shifts into water-retention mode to protect itself, primarily in terms of blood flow. In addition, alcohol disrupts your digestion by making your body metabolize the alcohol first (alcohol calories can't be used for energy) before your food is digested. Because of this digestion delay, there is a greater chance for your food to be stored as fat. Finally, alcohol disrupts your sleep cycles, and lower quality of sleep equals more stress, and that equals more bloating. So just like soda, cut the alcohol for seven days. Then I'll show you how to moderately work alcohol back into your life a little at a time in your Thrive phase. #### _Coffee and Caffeinated Tea_ Many of us love coffee and caffeinated tea—I know I do! They're cut from your Detox phase to help get your adrenal gland (your battery) cleaned up and to balance out your cortisol levels. The caffeine in coffee and tea triggers an over-release of adrenaline from your adrenal gland, which is then countered with a release of your stress hormone cortisol (too much cortisol in your body leads to unwanted belly fat). Most coffee and caffeinated tea drinkers have trained their bodies to rely on that caffeine rush—basically your body has become addicted to the caffeine. This causes you to use caffeine to mask some existing sleep deprivation and fatigue. Cutting caffeine will remove the fake
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a monetary judgment in the amount of the tax revenues plus interest and penalties. ¶ 10 StubHub removed the case to federal court on diversity grounds (see 28 U.S.C. § 1332(a) (2006)), and filed a motion to dismiss. The federal district court granted that motion. City of Chicago v. StubHub, Inc., 622 F. Supp. 2d 699, 704 (N.D. Ill. 2009). The federal district court stated that the City’s power to impose an obligation on StubHub to collect and remit the amusement tax depended upon the nature of the tax. Id. at 703. Because our appellate court had decided that ticket resales were sales of tangible personal property (see Mr. B’s, Inc. v. City of Chicago, 302 Ill. App. 3d 930, 937 (1998)), and the state legislature had preempted the City’s authority to tax such property (see 65 ILCS 5/8-11-6a (West 2010)), the federal district court held that the City lacked the authority to require StubHub to collect and remit the amusement tax incurred by its sellers. StubHub, 622 F. Supp. 2d at 703-04. ¶ 11 The City appealed. The federal circuit court first examined, then rejected, StubHub’s argument that federal law prohibited the City from imposing a tax on internet sites. City of Chicago v. StubHub!, Inc., 624 F.3d 363, 367 (7th Cir. 2010). The federal circuit court then discussed Illinois law, noting that in a diversity case a district court is bound by state appellate court case law, but a circuit court is not: “We could make a decision, confident that any error would be corrected by the state judiciary before too much time had passed. As far as we can tell, however, the state judiciary will be unable to address this subject unless we certify. There are only two pending cases, both in federal court.[1] *** Both suits began in state court and were removed under the diversity jurisdiction. Any similar suit likewise would be removable. *** This means that the state judiciary may never have an opportunity to resolve this dispute. The only way the federal judiciary can be sure that it is applying authentic state law is to certify the subject to state court.” Id. at 367-68. ¶ 12 The federal circuit court found no precedent from this court on the three principal questions in dispute, namely, “whether the tax works as an occupation tax, whether the 1 The other case is City of Chicago v. eBay, Inc., No. 10-1144, which was argued before the court of appeals in tandem with the StubHub case, and held in abeyance pending our decision here. See StubHub!, Inc., 624 F.3d at 367. According to StubHub, eBay is its “corporate parent.” -6- history of the 2005 amendment prevents Chicago from defining Internet auction sites as resellers’ agents, and whether the amusement tax is one on ‘tangible personal property.’ ” Id. at 367. Under Rule 20, the court certified a broader question: “whether municipalities may require electronic intermediaries to collect and remit amusement taxes on resold tickets.” Id. at 368. According to the federal circuit court, it phrased the question in that way “to ensure maximum flexibility for the state judiciary, which may elect to address any of the three sub- questions we have already identified, or may conclude that some other issue altogether determines the appropriate answer.” Id. We accepted certification, and allowed the County of Cook to file an amicus curiae brief in support of the City and eBay and Netchoice Coalition to file an amicus curiae brief on behalf of StubHub. ¶ 13 ANALYSIS ¶ 14 Initially, we must address the threshold question of whether StubHub is a “reseller’s agent” under the ordinance. If it is not, the ordinance does not apply. ¶ 15 StubHub argues it is not a reseller’s agent because it is not an agent for its users. StubHub notes that in order to obtain a license, it must certify that it is not its users’ agent. See 225 ILCS 407/10-27(c)(1) (West 2010). According to StubHub, this statutory requirement recognizes that internet auction listing services do not act as agents, but rather as marketplaces that bring buyers and sellers together. Further, StubHub asserts that under common law agency principles, it lacks control over its users. Though it may terminate a user’s access to its website, it does not dictate the terms of any sales. ¶ 16 The City argues that under the ordinance a reseller’s agent is simply a person who, for consideration, resells a ticket for the ticket’s owner or assists the owner in reselling the ticket. According to the City, StubHub fits this description. It allows ticket owners to list tickets for sale on its website, and offers them ways to do so that help potential buyers find the tickets they want. In return for these services, StubHub collects a fee from both buyers and sellers. ¶ 17 We agree with the City. The City is free to define terms in its code, and need not track common law agency principles. Under the ordinance, a reseller’s agent is “a person who, for consideration, resells a ticket on behalf of the ticket’s owner or assists the owner in reselling the ticket.” Chicago Municipal Code § 4-156-010 (amended May 24, 2006). That term applies to StubHub because it provides services that help users sell their tickets, and it is compensated for those services. See StubHub, 624 F.3d at 366-67 (“intermediaries that take an active role in staging an auction and exchanging goods for money, as StubHub[ ] does, are resellers’ agents”). We now turn to the central issue in this case: whether the City has the authority to impose an obligation upon online auctioneers to collect and remit its amusement tax. Our discussion begins with home rule. ¶ 18 Under the 1870 Illinois Constitution, the balance of power between our state and local governments was heavily weighted toward the state. The 1970 Illinois Constitution drastically altered that balance, giving local governments more autonomy. Schillerstrom Homes, Inc. v. City of Naperville, 198 Ill. 2d 281, 286-87 (2001); City of Evanston v. Create, Inc., 85 Ill. 2d 101, 107 (1981) (quoting 4 Record of Proceedings, Sixth Illinois Constitutional Convention 3024). Municipalities now enjoy “the broadest powers possible” -7- (Scadron v. City of Des Plaines, 153 Ill. 2d 164, 174 (1992)) under the Constitution. Section 6(a) of article VII provides: “Except as limited by this Section, a home rule unit may exercise any power and perform any function pertaining to its government and affairs including, but not limited to, the power to regulate for the protection of the public health, safety, morals and welfare; to license; to tax; and to incur debt.” Ill. Const. 1970, art. VII, § 6(a). ¶ 19 Section 6(a) gives municipalities any powers pertaining to their governments and affairs, including the power to tax, but not the power over matters such as divorce, real property, trusts, and contracts (7 Record of Proceedings, Sixth Illinois Constitutional Convention 1621). The framers’ intent was clear: “the powers of home-rule units relate to their own problems,” not problems more competently solved by the state. Id. The framers offered examples of problems suited to state or local authority, and suggestions on when one or the other would prevail. See Id. at 1652-57. The framers, however, understood that further interpretation of section 6(a)’s intentionally imprecise language would fall to the judicial branch. 4 Record of Proceedings, Sixth Illinois Constitutional Convention 3052. ¶ 20 That task has involved defining the parameters of the qualifying phrase “pertaining to.” In this regard, Professor David Baum, counsel to the Committee on Local Government at the Sixth Illinois Constitutional Convention, has been a valuable resource to the court. In 1972, he wrote two articles, A Tentative Survey of Illinois Home Rule (Part I): Powers and Limitations, 1972 U. Ill. L.F. 137 (hereinafter Part I), and A Tentative Survey of Illinois Home Rule (Part II): Legislative Control, Transition Problems, and Intergovernmental Conflict, 1972 U. Ill. L.F. 559 (hereinafter Part II), both of which touch upon the tensions inherent in this area, and confirm
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and nearby areas $ AVG Average annual compensation $ ADJ Adjusted for cost of living OPEN JOBS Number of job opportunities Ladders Rank is a grading system that calculates the optimal cities for this job title. The formula is based on annual compensation, amount of open jobs, and the Adjusted Cost of Living Index (ACLI). 5Senior Quality Assurance Engineer jobsin Victoria In this role, you will be responsible for checking and advising on design specifications of the new plant and equipment, the correct selection and application of materials and design cases to ensure their safety and integrity of existing and new assets. This person is responsible for reviewing requirements; assessing impact of new features and modifications into the existing system; creating, maintaining and executing test plans and test cases; deployment and updating test environments and defect management. In this role, you will provide non-personal professional services for the client to assist with planning, coordinating, conducting, and leading activities of a team conducting protection program higher headquarters assessments at Army installations.With its on-property amenities including a restaurant, spa, outdoor pool, hot tub and more, free airport shuttle and kid-friendly, pet-friendly policy, it's no wonder the non-smoking Renaissance Palm Springs is one of our guests' favorite stopovers in town. The five-story Renaissance is a business traveler's hotel that's pro family. Inside its 255 rooms, you'll find Wi-Fi (for a fee,) an LCD TV, complimentary coffee and tea, a free newspaper and more. Stay in shape at the on-site fitness center while your kids enjoy the children's pool and sandbox, try a treatment at the on-site spa or flex your work muscles at the business center. Indulge your appetite for casual California cuisine at the on-property restaurant, or just enjoy the mountain views. The Renaissance is less than two miles from Palm Springs International Airport and 500 feet from the convention center. Steps away, you'll find the eclectic eateries and boutique shops of Palm Canyon Drive. our guests give the Renaissance a thumbs up for its "spacious rooms" with "comfy beds," "posh pool area" and "amazing staff," making it a snazzy selection for your next Palm Springs stay. Dogs up to 50 pounds allowed. There is a $50 one time pet fee per pet. Before you visit an establishment or place, please contact them and verify that they are still dog-friendly and available, as policies and management change frequently. All places listed on DogFriendly.com require your dog to be leashed and under your direct control unless specified otherwise by an establishments (including parks and beaches) management. Please be aware of local Breed-Specific Laws that may be in place where you are visiting. The information on this site is not a recommendation. DogFriendly.com, Inc. makes no warranties or representations of any kind, express or implied, as to the operation of the site or the information, content, materials, or products included on this site. If you find an establishment that no longer allows dogs, please let us know so we can remove them from our list. For full Rules and Regulations for Use of This Site, including the legal disclaimer and copyright notices, click here before using the site.A favicon is something that you've perhaps seen but didn't know it has a name. That was me a while ago. After a few attempts (trial and error) I managed to add a favicon to Highball Blog and in this post I'm gonna teach you how to do it on your Blogger/Blogspot blog. Favicons are those small images that you see in the browser's address bar, shown before the URL of a website or blog. Not all websites display them but those who do are more likely to make a favorable impression on the viewer. We've got so used to see logos attached to any kind of venture that favicons are their normal extension on the web - in the browser to be more specific. Let's get to the point and see... How You Can Add a Favicon to Your Blogger Blog Before jumping into technical stuff let's agree that you need to design a logo for your blog. And when I say design I don't mean you have to create a masterpiece in seven colors, gradients and textures. No! It's all about simplicity. If you think your blog should get an original symbol logo then create a logo but in most cases - especially with personal blogs - having your name's initials in a small square or circle will do. Tips for logo design: Work with three colors maximum Use solid colors (no gradients, no textures/pattern fills) Use simple shapes Work with few elements (don't crowd the logo with too many shapes) Make sure your logo looks good in black and white too Think about it from a branding perspective (make it memorable) Create the logo in an image editor/computer graphics software that you're familiarized with. If you don't have such software installed on your computer then I suggest you go and download Inkscape - an open source vector graphics editor that competes with major expensive software. Save your image as PNG file. Now you need to resize your image. You can do that with Microsoft Office Picture Manager in a few easy steps: Open your file Hit the Edit Pictures button Click Resize (the right sidebar menu) Enter 16 in the Custom width x height fields (favicons must be 16 pixels wide/16 pixels tall for a proper display in the browser's address bar) Click OK Save your new image with a different name as to not replace it with the original one (Save as... - name-of-file-16-px.png) Click on the image below for a visual explanation of the process. Once you have the new resized image you must host it somewhere online. I recommend Media Fire as it's free, reliable and convenient. Create an account and upload your image. Note that you can use Media Fire for sending files to people or for storing your own important documents - it can be an alternative to Dropbox (not that smart as Dropbox but good enough for this purpose). After you upload the picture to Media Fire go through the following steps: Click on the Share button to see all the sharing options Copy the HTML Embed Code and paste it into a Notepad blank document Look for the piece of code that looks like this: img src="http://www.mediafire.com/imgbnc.php/325ea55e0637fca99dc362b7970078862g.jpg" This particular piece of code (purple line) is the link of your image hosted on Media Fire; img src stands for Image Source Copy the code within the inverted commas and paste it lower in your Notepad document as you'll need it in the next step. Please note that your code will be different that mine! Replace the red line with your favicon source code (purple line) that you saved earlier in the Notepad document Click Save Template Done! Note that Highball Blog runs on Three Column Minibox Template which I downloaded from here. If adding the favicon doesn't work on your current blog theme, you may find other solutions in these Google search results. This article will be added to the list you can see in the right sidebar called Tutorials for Bloggers. If you think these technical posts on blogging belong somewhere else, let me know and I'll create a separate blog just for that. I tend to mix these two topics - internet and outdoor activities - as I love them both. :-) Hey! You Look Cool in a Highball Shirt Resources The Essential Guide for Smooth Vids How To Master Your GoPro Camera Like a Pro (even if you don't know anything about shooting or editing videos) + How To Make Money on YouTube (Bonus Section) Don't freak out! I hate spam too. Your email is safe with me. + You'll Also Get These Extra (FREE) Materials: How To Get Free Outdoor Gear from Sponsors How To Make Viral Videos - 3 Lessons from Devin Graham (King of YouTube) 3 Cool Ways To Get Paying Clients as a Videographer How To Be Creative without The Pressure You Don't Have To Struggle To Learn How To Shoot and Edit GoPro Videos on Your Own. Take The GoPro Video Editing Course and Easily Publish Your First Video without Mistakes. Hi! My name is Constantin and I'm an outdoorsy dude who enjoys shooting and editing action sports videos. Here you can learn GoPro tips, how to build DIY video gear and you can also read our outdoor gear reviews. More about me here.Blog Everything you wanted to know about SAP CRM 7.0 Ehp 1 (but were afraid to ask) by Antoine Cadot-Wood January 11, 2012 SAP CRM 7.0 Ehp 1 has been available to everyone for a bit more than half a year now. And for those of you on the fence about when and how to implement it, I have two New Year’s presents to help you with your decisions. The first is a podcast with CRM Expert’s very own advisor and author Christian Matz, Managing Director at ecenta America and longtime
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is evidence of the "western" style in Portugal as early as 4000 BC. Don't recall the exact date of the earliest, but I believe it to be neolithic, and certainly pre-dating some of the alleged migrations put forth by kurganists. I know we disagree on this, and one could write a book on it (and people have). So, here just a few points specifically for most of north/central Europe (west of the steppe/plains): Firstly, re timelines for people, culture, and language (IE) from the East to reach the areas west of the plains: If it is supposed to be Globular Amphora (GA), then (i) it is way too late given modern linguistic timings of the IE tree, and (ii) contradicts the fact that the area west of it a few hundred years later developed its own early and mid bronze age with documented trade and cultural exchange from the south (specifically over the Alps and with the Balkans/ Greece), not the east. Finally, GA has cultural continuity with the local Funnelbeaker (FB) offshoot of LBK, starts with megalithic graves and ends in "Hockergäber, no Tumuli - none of that is eastern. Associated cattle graves are a cultural continuity with FB, not of eastern origin, then, either. It can't be Baden either, because besides the timing issue, that is associated with the northern Balkans and not the east, and they had a mix of regular burials and cremations. Also, Baden has cultural continuity with the local Lengyel offshoot of LBK. If it is the bronze age, you have the problem that tumuli with the characteristic grave position don't occur until 600 years after the local early bronze age. Secondly, the proposed "driving agents" and supposedly introduced cultural items are mostly flawed in this region: - there are almost no warrior-chieftains graves; society was largely egalitarian (as before and after, even into the iron age, north of the Celts) - horses could not be used effectively because of heavy forestation, heavy soil, and expensive/unavailable winter fodder. And indeed, north of the Danube horses were extremely rare until Roman times. - chariots are equally useless and indeed were not used. The first usage of chariots is in south, in the celtic region, and not until the iron age. - the early bronze age is local there, with local production and import of raw materials from the north and the south, not the east. - there is local cultural continuity; very few things are adopted from the east (tumuli graves with characteristic position, but there are also cremations), most items are imported/adopted from the south, or are evolutions from local cultural continuity. Basically, by the time you get to western Poland, there is almost nothing left of any sorts of Kurgan (or hybrid) cultural package. Most importantly, anything that could have been causal in forcing the adoption of a new language is lacking. I was unable to post this to the new Dodecad entry but it is relevant to this thread. Perhaps Dienekes would be kind enough to copy it over to the other blog. http://dodecad.blogspot.com/2011/10/eurasia7-calculator.html#comments << [Kalash] proportions are consistent with previous results, showing them to be a "West Asian" population (62.4%) with substantial "South Asian" admixture (37.1%), and near-complete absence of any other genetic components. >> And yet the Kalash show strong traces of blondism of the hair and eyes. (Search google images for "Kalash".) Does this allude to an (partial?) Asian origin of Nordics? And again we see that the West Asian ancestral component and the Atlantic_Baltic component are much closer to each other (0.028) than they are to the Southern [European?] (0.055/ 0.058). And they are nearly as close to the South Asian (0.06/ 0/065) as they are to the Southern. Moreover they have simimlar distances to all the other components -- while the other components do not have similar distances? The data thus seems to suggest a West Asian origin of the Atlantic_Baltic [North European?] component. The present analysis thus seems consistent with an Asian origin of the Indo-Europeans. Supposedly they are publishing the results soon. At AGBT 2012 the slides showed that Otzi is equally distant, all genes-wise, to Tuscans and the rest of W and N Europeans (except Finns who are more distant). "Unfortunately there aren't any whole exome data for Sardinians yet (or Basques for that matter)" The low-pass (2-3+X genomes) Sardinian project which was a subject of another talk there is huge (6,000 individuals from 4 small towns, mostly with medical research in mind) but barely analyzed. I don't think that there were any meaningful comparisons with their dataset. The Sardinian data which Carlos Bustamante used were SNPs (best match genome-wise, and the Y hap was specific to Sardinia and Corsica). My notes don't say where this Sardinia SNP dataset came from, and it didn't sound like a new development. What seemed new was the conspicuous lack of closest similarity to 100- Genomes' Tuscans. Sorry I should have read this entry *before* listening to his talk, but at least I found your blog because of it ;) Old Blog Archive Dienekes' Anthropology blog is dedicated to human population genetics, physical anthropology, archaeology, and history. You are free to reuse any of the materials of this blog for non-commercial purposes, as long as you attribute them to Dienekes Pontikos and provide a link to either the individual blog entry or to Dienekes Anthropology Blog. Feel free to send e-mail to Dienekes Pontikos, or follow @dienekesp on Twitter.New 0-Day Flaw Affecting Most Android Phones Being Exploited in the Wild Another day, another revelation of a critical unpatched zero-day vulnerability, this time in the world’s most widely used mobile operating system, Android. What’s more? The Android zero-day vulnerability has also been found to be exploited in the wild by the Israeli surveillance vendor NSO Group—infamous for selling zero-day exploits to governments—or one of its customers, to gain control of their targets’ Android devices. Discovered by Project Zero researcher Maddie Stone, the details and a proof-of-concept exploit for the high-severity security vulnerability, tracked as CVE-2019-2215, has been made public today—just seven days after reporting it to the Android security team. The zero-day is a use-after-free vulnerability in the Android kernel’s binder driver that can allow a local privileged attacker or an app to escalate their privileges to gain root access to a vulnerable device and potentially take full remote control of the device. Vulnerable Android Devices The vulnerability resides in versions of Android kernel released before April last year, a patch for which was included in the 4.14 LTS Linux kernel released in December 2017 but was only incorporated in AOSP Android kernel versions 3.18, 4.4 and 4.9. Therefore, most Android devices manufactured and sold by a majority of vendors with the unpatched kernel are still vulnerable to this vulnerability even after having the latest Android updates, including below-listed popular smartphone models : Pixel 1 Pixel 1 XL Pixel 2 Pixel 2 XL Huawei P20 Xiaomi Redmi 5A Xiaomi Redmi Note 5 Xiaomi A1 Oppo A3 Moto Z3 Oreo LG phones Samsung S7 Samsung S8 Samsung S9 To be noted, Pixel 3, 3 XL, and 3a devices running the latest Android kernels are not vulnerable to the issue. Android Flaw Can Be Exploited Remotely According to the researcher, since the issue is “accessible from inside the Chrome sandbox,” the Android kernel zero-day vulnerability can also be exploited remotely by combining it with a separate Chrome rendering flaw. “The bug is a local privilege escalation vulnerability that allows for a full compromise of a vulnerable device. If the exploit is delivered via the Web, it only needs to be paired with a renderer exploit, as this vulnerability is accessible through the sandbox,” Stone says in the Chromium blog. “I’ve attached a local exploit proof-of-concept to demonstrate how this bug can be used to gain arbitrary kernel read/write when running locally. It only requires the untrusted app code execution to exploit CVE-2019-2215. I’ve also attached a screenshot (success.png) of the POC running on a Pixel 2, running Android 10 with security patch level September 2019.” Patches to be Made Available Soon Though Google will release a patch for this vulnerability in its October’s Android Security Bulletin in the coming days and also notified OEMs, most affected devices would not likely receive the patch immediately, unlike Google Pixel 1 and 2.
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be able to get you the module. Naran Hi Hugh, I was looking for similar solution to reflect the actual manufacturing cost in the financial inventory, were you be able to develop module for this..? Thanks, Naran Naran Hi Rajive, I am exactly looking for the same to reflect the actual manufacturing cost reflected in accounting inventory, instead of taking the cost price defined for the finished product, were you be able to accomplish this..?INTRODUCTION ============ Pruritus is the most common symptom of dermatologic disorders. Previous studies have reported that pruritus frequency is associated with psoriasis severity to varying degrees[@B1],[@B2]. Many possible mediators have been suggested to transmit or modulate pruritus in psoriasis; however, the precise mechanism and the mediators involved are still unclear[@B3]. Neurogenic factors, including altered innervations, neuropeptides, opioids, and nerve growth factors (NGFs), have been implicated as important mediators in psoriatic skin[@B4]. Nakamura et al.[@B4] reported high numbers of protein gene product 9.5 (PGP 9.5)-immunoreactive nerve fibers in the epidermis and upper dermis, and of perivascular nerve fibers containing substance P (SP) in psoriatic lesions. These findings indicate that hyperinnervation in psoriatic lesions is involved in the pathogenesis of pruritus associated with psoriasis. However, other investigators have reported conflicting results, showing decreased nerve density in psoriatic lesions compared with that in nonlesional skin[@B5]. The scalp is the most frequently affected area in patients with psoriasis. A previous study indicated that 57% of patients with scalp psoriasis believed that it was a psychosocial handicap, and that the most annoying symptom was itching[@B6]. The scalp has a complex neuroanatomy with an abundance of sensory neural end organs in the pilosebaceous unit[@B7]. Therefore, understanding the clinical characteristics and unique features of the itch mechanism in the scalp is important for the development of effective therapies. However, few studies have focused on pruritus in scalp psoriasis. In the present study, we investigated the clinical characteristics of pruritus associated with scalp psoriasis and examined intraepidermal nerve fiber (IENF) density in scalp psoriatic lesions. Furthermore, we evaluated the correlation among scalp psoriasis severity, IENF density, and pruritus intensity. MATERIALS AND METHODS ===================== Subjects -------- Patients who were at least 18 years of age and diagnosed with psoriasis with scalp involvement were eligible for the study. Those with other underlying pruritogenic diseases of the scalp, including seborrheic dermatitis, atopic dermatitis, contact dermatitis, lichen planopilaris, folliculitis, and malignancy, were excluded. Written informed consent was obtained from all patients. The study protocol was approved by the institutional review board of Pusan National University Hospital (IRB No. D-1305-016-015), and the study was conducted according to the ethical guidelines of the Declaration of Helsinki. Measurement of the severity of scalp psoriasis and itching ---------------------------------------------------------- We used the psoriasis scalp severity index (PSSI), which corresponds to the scalp-modified psoriasis area severity index (PASI). The resulting values were 0 to 72, analogous to the PASI values. The Leuven Itch Scale (LIS), a questionnaire that evaluates the dimensions of the itch experience, was used in this study[@B8]. All patients were asked to complete a questionnaire about the scalp. We defined the negative impact of itching as an answer of \"sometimes\", \"often\", or \"always\" to questions about \"consequences of itching\" in the LIS. The subjective mean itch intensity in the past month was evaluated by using the visual analogue scale (VAS) score: from 0 (for no itch) to 10 (for maximum unbearable itch). Skin biopsies and immunohistochemistry -------------------------------------- Punch biopsies (4 mm diameter) were taken from the site with the most itch at the time of the biopsy in the psoriatic scalp and from the nonlesional scalp (nonlesional and nonpruritic site ≤10 mm from the site of the primary lesion) of 19 patients. Tissues were rapidly dissected, post-fixed in fixative solution (4% paraformaldehyde and 0.4% picric acid in 0.16 M sodium phosphate buffer, pH 6.9) for 90 minutes, and rinsed in 0.1 M phosphate buffer (pH 7.4) containing 10% sucrose (prepared in phosphate buffered saline \[PBS\]) for at least 24 hours as an optimal cutting temperature compound (Sakura Finetek Japan Co. Ltd., Tokyo, Japan). Specimens were frozen in isopentane that was cooled with liquid nitrogen and stored at -70℃. Sections were cut (25 µm) in a cryostat and air-dried overnight at room temperature. Slide-mounted tissue sections were rehydrated briefly in PBS and incubated with blocking buffer (blocking solution with goat serum; GeneTex Inc., Irvine, CA, USA) for 1 to 3 hours at room temperature. The primary antibodies used in this study were polyclonal antibodies against the neuron-specific hydrolase PGP 9.5 (Chemicon, Temecula, CA, USA). Primary antibodies were diluted in PBS to the appropriate working dilution (1:1,000). Blocking buffer was removed, and the slides were then incubated at 4℃ for 24 hours with primary antibodies. Sections were rinsed thrice in PBS and then incubated for 1 hour at room temperature with secondary antibodies (Alexa Fluor 488 goat anti-rabbit IgG; Life Technologies, Carlsbad, CA, USA). Sections were then mounted in a mixture of PBS and glycerol (1:3) containing 0.1% *p*-phenylenediamine. Semiquantitative measurements ----------------------------- The samples were examined with a LEICA TCS SP 2 confocal microscope and measured using Leica confocal software (Leica Microsystems, Mannheim, Germany). We scanned for subepidermal and intraepidermal nerves through two planes, horizontally along the epidermaldermal border and vertically by focusing through the thickness of the section, to detect each nerve branch and its course as suggested in the published guidelines[@B9]. The length of the epidermis was measured with Olympus DP soft analySIS Image Processing (version 3.2) software. In a blinded manner, two trained researchers (TW. K and WH. S) counted the total number of IENF clearly penetrating the basement membrane in each section by following established criteria[@B9] at ×400 magnification; however, the intraobserver and interobserver reliabilities was untested and variability was not calculated. Three specimens per biopsy were counted; the mean value was determined and divided by the epidermal length of the biopsy. The IENF density was calculated as the mean number of nerve fibers per millimeter epidermal length (IENF/mm). Statistical analysis -------------------- Statistical analysis was performed with PASW Statistics ver. 18.0 for Windows (IBM Co., Armonk, NY, USA). Wilcoxon test was performed to compare the IENF density between lesions and nonlesions. The Spearman p test was performed to determine whether a significant correlation existed among PSSI, pruritus intensity, and IENF density. In all statistical tests, a two-sided significance test was performed and *p*\<0.05 was considered statistically significant. RESULTS ======= Study patients -------------- A total of 80 patients (53 men, 27 women; mean age, 46.4 years; mean PSSI, 19.9) with scalp psoriasis were enrolled in the study ([Table 1](#T1){ref-type="table"}). Immunoreactivity to PGP 9.5 was investigated in 19 patients. The mean VAS of pruritus was 3.81±3.06 for all patients and 5.84±2.95 for the 19 patients. There was a moderate positive relation between PSSI score and VAS of pruritus in all scalp psoriasis patients (Spearman rank correlation; r=0.225 and *p*=0.044) ([Fig. 1](#F1){ref-type="fig"}). The mean VAS of distress due to itching was 4.94±3.25 for all patients and 6.0±3.43 for the 19 patients. Clinical characteristics of pruritus associated with scalp psoriasis -------------------------------------------------------------------- Sixty-four patients (80.0%) experienced pruritus associated with scalp psoriasis to varying degrees ([Table 2](#T2){ref-type="table"}). Of these 64 patients, 28 (35.0%) had persistent pruritus. Pruritus lasted up to 1 hour in 50 patients (62.5%), and the severity was rated as greater in the evening and at night in 38 patients (47.5%). For questions on aggravating factors of pruritus, the most common answer given by the participants was \"when I was stressed out\" (35.0%), followed by \"in a hot environment\" (18.8%), \"when sweating\" (17.5%), \"during a change in the weather\" (12.5%), and \"in a cold environment\" (10.0%). Fifty-four patients (67.5%) had lesion from scratching because of the pruritus, and pruritus led to a reduction in the quality of life and social contact in 42 patients (52.5%) and 22 patients (27.5%), respectively. Furthermore, pruritus associated with scalp psoriasis had a negative impact on concentration (48.8%), behavior toward others (35.0%), routine activities (35.0
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19886903} ======= Vection and head sway data were analyzed by repeated analyses of variance to identify the main and interaction effects of optic flow direction and flow locations. Familywise errors were corrected with Shaffer's modified sequentially rejective Bonferroni procedure, and the adjusted *p* values are shown for the post hoc analyses. We used an open source function library working on R software named *Anovakun* for the statistical analysis (<http://riseki.php.xdomain.jp/index.php?ANOVA%E5%90%9B>). Vection Strength Ratings {#sec8-2041669519886903} ------------------------ Despite the relatively short presentation of 10 s, most of the test trials exceeded zero rating, except for two trials by two participants with zero rating. [Figure 2](#fig2-2041669519886903){ref-type="fig"} shows the mean vection strength ratings across participants under the two optic flow conditions for the three flow location conditions. There were significant main effects of optic flow, *F*(1, 8) = 6.17, *p* = .038, η^2^ = 0.021, and flow location, *F*(2, 16) = 23.85, *p* \< .001, η^2^ = 0.303. The two-way interaction of optic flow and flow location was not significant, *F*(2, 16) = 1.23, *p* = .318, η^2^ = 0.005. Multiple comparisons of flow location revealed stronger vection ratings of lower field versus upper field condition, *t*(8) = 3.62, *p* = .007, and stronger vection ratings of full-field versus upper, *t*(8) = 6.53, *p* = .001, and lower field conditions, *t*(8) = 3.50, *p* = .008. ![Mean vection strength ratings for each location and direction of optic flow. Error bars represent standard error of the mean. Each line represents data from an individual participant.](10.1177_2041669519886903-fig2){#fig2-2041669519886903} Head Displacement {#sec9-2041669519886903} ----------------- Before the analysis, we discarded the sampled head positions in the first 10 frames (200 ms) from stimulus onset to cope with the frame rate drop at the beginning of each presentation. [Figure 3](#fig3-2041669519886903){ref-type="fig"} shows the mean time series of anterior--posterior head sway obtained from the HMD position across participants relative to the initial HMD position of the stimulus presentation (base position). The 95% confidence intervals of each sampling point were computed by a bias-corrected and accelerated (BCa) bootstrap method (Efron, 1987). Contracting stimuli appeared to produce forward head sway, while expanding stimuli appeared to produce slight backward sway. Moreover, the amplitude of the head sway appeared different across flow locations at least for the contracting pattern. Specifically, for the contracting flow, lower and full-field conditions tended to produce larger forward head sway compared with the upper field condition. It is also notable that mean head displacement reached asymptote in the early period of stimulus presentation for both expansion and contraction, with increasing confidence intervals over time. To visualize the time course of the head displacement more clearly, we plotted *t* values as an indicator of deviation from the base position as a function of time for each condition ([Figure 4](#fig4-2041669519886903){ref-type="fig"}). The *t* values are more remarkable in the early period of stimulus presentation, gradually returning to baseline in the late period, possibly because of sway back due to nonvisual (e.g., vestibular) signals. We therefore divided the head sway data into the first 5 s (early period) and the last 5 s (late period) and analyzed them separately. Note that this decision to split the data was post hoc. ![Mean head displacement trajectories relative to the base position across all participants for each flow location and direction. Lines represent average head position across trials in each condition. Ribbons represent the 95% confidence intervals for each data point, obtained by the bootstrap method. Positive and negative values on the vertical axis represent anterior and posterior displacement, respectively.](10.1177_2041669519886903-fig3){#fig3-2041669519886903} ![Time series of sample-specific *t* values from the base position across participants for each flow location and direction. Positive and negative values on the vertical axis represent the head moving anteriorly or posteriorly relative to the base position, respectively.](10.1177_2041669519886903-fig4){#fig4-2041669519886903} We calculated the head displacement bias for each trial as the mean head displacement during optic flow presentation relative to the base position. Head displacement bias ("head displacement") for each trial was defined as follows: $$\text{head}\ \text{displacement} = \frac{1}{N}\sum\limits_{n}^{N}x_{n}\ $$where *x* is the head position for each sampled point, and *N* is the number of sampled data points. We also calculated the absolute value of head displacement to analyze the magnitude of the head displacement. The absolute head displacement for each trial was defined as follows: $$\text{Absolute}\ \text{head}\ \text{displacement} = \left| {\text{head}\ \text{displacement}} \right|$$ We then averaged head displacement and absolute head displacement for each participant over six trials per condition. The bar plots in [Figure 5](#fig5-2041669519886903){ref-type="fig"} show the mean head displacement across all participants during early and late periods of the stimulus presentation under the two optic flow conditions and the three flow location conditions. In the early period, there was a significant main effect of optic flow direction, *F*(1, 8) = 8.14, *p* = .021, η^2^ = 0.262, indicating different biases in head displacement for contraction and expansion, but no significant main effect of flow location, *F*(2, 16) = 1.78, *p* = .200, η^2^ = 0.024. There was a significant interaction of optic flow and flow location, *F*(2, 16) = 6.07, *p* = .011, η^2^ = 0.089. Subsequent analysis revealed significant simple main effects of optic flow for full-field, *F*(1, 8) = 6.78, *p* = .031, η^2^ = 0.374, and lower field, *F*(1, 8) = 10.21, *p* = .013, η^2^ = 0.476, conditions but not for the upper field condition, *F*(1, 8) = 0.57, *p* = .474, η^2^ = 0.021. There was a simple main effect of flow location for the contracting pattern, *F*(2, 16) = 7.45, *p* = .005, η^2^ = 0.225, but not for the expanding pattern, *F*(2, 16) = 1.14, *p* = .345, η^2^ = 0.054. Multiple comparisons of the flow location for contraction revealed larger head displacement in lower and full-field conditions than the upper field condition, *t*(8) = 4.20, *p* = .009; *t*(8) = 2.75, *p* = .025, but no significant difference between lower field and full-field conditions, *t*(8) = 0.26, *p* = .803. In the late period, there was a significant main effect of flow location, *F*(2, 16) = 4.25, *p* = .033, η^2^ = 0.036, whereas no significant main effect of optic flow, *F*(1, 8) = 2.82, *p* = .132, η^2^ = 0.059, or two-way interaction, *F*(2, 16) = 0.473, *p* = .632, η^2^ = 0.010, was observed. Multiple comparisons revealed larger head displacement in the full-field versus upper field condition, *t*(8) = 3.02, *p* = .049, but no significant difference between upper and lower field conditions, *t*(8) = 1.88, *p* = .097, or full and lower field conditions, *t*(8) = 1.08, *p* = .313. ![Mean head displacement relative to the base position for each location and direction of optic flow. We separately calculated the mean head displacement for (a) first 5 s and (b) last 5 s from the stimulus onset. Each line represents data from an individual participant.
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15, 25683, 253, 45105, 422, 3558, 310, 4229, 281, 253, 8109, 24026, 407, 247, 5199, 824, 347, 271, 519, 42527, 5199, 970, 271, 21134, 13, 323, 1650, 13, 271, 30595, 8056, 21134, 13, 247, 48766, 21134, 390, 247, 5461, 375, 33513, 21134, 13, 390, 247, 5199, 273, 13532, 253, 45105, 422, 3558, 715, 247, 24096, 4447, 327, 253, 8109, 24026, 15, 3932, 253, 45105, 422, 3558, 556, 34661, 272, 7017, 36331, 6636, 342, 247, 19663, 4891, 13, 253, 45105, 422, 3558, 476, 320, 8244, 42159, 281, 253, 8109, 24026, 13, 285, 253, 11254, 273, 253, 45105, 422, 3558, 432, 253, 987, 1899, 327, 253, 8109, 24026, 12952, 1955, 281, 10935, 390, 22634, 476, 320, 14415, 13, 534, 5644, 281, 14314, 273, 12320, 273, 35952, 15, 187, 3039, 271, 21134, 310, 908, 323, 18505, 253, 45105, 422, 3558, 281, 253, 8109, 4589, 335, 7855, 13, 1557, 943, 13027, 320, 2668, 594, 347, 281, 5206, 271, 21134, 8479, 642, 260, 5744, 272, 390, 33118, 273, 253, 45105, 422, 3558, 13, 824, 347, 271, 30595, 8056, 21134, 15, 187, 510, 8109, 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2144, 281, 320, 29422, 13, 285, 6447, 35952, 476, 320, 8069, 5196, 15, 2091, 247, 1262, 1907, 581, 45105, 422, 3558, 4229, 281, 253, 8109, 24026, 310, 908, 13, 352, 310, 13027, 326, 247, 35198, 323, 44636, 247, 35952, 5558, 310, 4447, 327, 253, 35952, 2553, 15, 187, 510, 5281, 273, 253, 45105, 422, 3558, 310, 417, 3782, 3710, 285, 3797, 13, 323, 1650, 13, 247, 5084, 274, 37278, 285, 247, 6278, 43035, 16745, 37278, 1907, 247, 29740, 390, 13284, 17656, 2831, 14, 4674, 15, 187, 510, 1979, 273, 253, 45105, 422, 3558, 671, 310, 417, 3782, 3710, 2530, 326, 247, 6799, 1180, 273, 253, 45105, 422, 2758, 403, 7032, 273, 1146, 4229, 281, 247, 8109, 24026, 15, 25585, 31821, 253, 1979, 310, 281, 271, 6070, 824, 326, 1016, 45105, 422, 3558, 11521, 1561, 247, 6278, 2170, 1907, 247, 1930, 2978, 273, 608, 281, 2233, 5823, 15, 3308, 13, 271, 45105, 422, 3558, 273, 247, 5084, 274, 37278, 5281, 13027, 556, 247, 9080, 273, 608, 281, 2233, 5823, 285, 326, 273, 247, 6278, 43035, 5281, 13027, 556, 247, 1930, 2978, 273, 608, 281, 2233, 5823, 15, 4952, 604, 253, 1979, 273, 253, 45105, 422, 3558, 310, 4577, 685, 608, 5823, 13, 352, 556, 247, 1175, 35952, 3045, 13, 533, 13, 672, 271, 45105, 422, 1262, 273, 247, 1781, 1979, 310, 908, 13, 1512, 1142, 45105, 422, 2758, 1364, 320, 908, 281, 4044, 35952, 6733, 273, 271, 12207, 6070, 285, 3021, 253, 45105, 422, 3558, 556, 4105, 8542, 414, 15, 4952, 604, 253, 1979, 273, 253, 45105, 422, 3558, 310, 4067, 685, 2233, 5823, 13, 253, 45105, 422, 1262, 15646, 247, 35952, 3045, 273, 271, 12207, 6070, 2530, 326, 24911, 953, 323, 44636, 247, 35952, 5558, 403, 4447, 327, 253, 490, 83, 4930, 2553, 13, 533, 13, 253, 1180, 273, 253, 45105, 422, 2758, 591, 3943, 2170, 273, 247, 1329, 1364, 320, 1355, 285, 352, 778, 320, 2834, 281, 20685, 6447, 35952, 15, 187, 510, 9544, 313, 74, 15, 70, 904, 2978, 20277, 281, 253, 490, 83, 4930, 2553, 10, 273, 253, 45105, 422, 3558, 310, 417, 3782, 3710, 13, 533, 310, 13027, 275, 253, 2491, 273, 495, 281, 884, 5823, 15, 2058, 247, 9544, 4577, 685, 495, 5823, 13, 352, 310, 45991, 281, 6431, 253, 45105, 422, 3558, 15, 496, 4499, 13, 387, 247, 9544, 27433, 884, 5823, 13, 352, 4916, 2834, 281, 17568, 4647, 247, 35952, 5558, 689, 253, 490, 83, 4930, 3558, 15, 187, 510, 3268, 273, 253, 45105, 422, 2758, 275, 271, 45105, 422, 1262, 310, 417, 3782, 3710, 2530, 326, 253, 45105, 422, 2758, 403, 9619, 17568, 5939, 689, 253, 2862, 31998, 2170, 273, 253, 2553, 273, 253 ]
ive grain is used. When an amine is used as a soluble solid for silicon wafer, the rate of polishing can be enhanced. When an organic acid is used as a soluble solid for polishing metal substrates and glass substrates. The amount of the soluble solid is preferably such that it occupies at least 10% by weight based on the total volume of the interconnecting minute pores. If the amount of the soluble solid is too small, it would be difficult to attain the benefits of the soluble solid, i.e., the enhancement of durability of silica molding, the reduction of abrasion of silica molding, and the enhancement of polishing rate. Process for Producing Abrasive Member The process for producing the abrasive member of the invention will now be described. First, the process for producing a silica molding of the abrasive member is not particularly limited provided that a silica molding having the above-specified properties is obtained. For example, the silica molding is made by press-molding a silica powder which is a wet process silica (i.e., precipitated silica) powder prepared from sodium silicate, or a dry process silica prepared by vapor phase thermal decomposition of silicon tetrachloride, or by molding a slurry of these silica powders. The thus-obtained molded products are usually sintered. The silica molding also can be made by piling a fine silica powder directly into a molded form (usually called as soot) which powder is as-prepared by vapor phase thermal decomposition of silicon tetrachloride. More specifically, a powdery raw material can be pre-molded, followed by classification using a sieve. The pressure under which the raw material is pre-molded varies depending upon the particular properties of the powder, but is usually in the range of 5 to 1,000 kg/cm2. To improve the moldability of the powdery raw material, it can be made into granules, for example, by a spray drying or rolling method, or a binder solution can be incorporated therein. A pore-forming agent can be incorporated. As specific examples of the pore-forming agent, there can be mentioned waxes such as paraffin wax and microcrystalline wax, powdery acrylic resins such as polymethyl methacrylate and polybutyl methacrylate, powdery olefin resins such as polyethylene, polypropylene, an ethylene-vinyl acetate copolymer and an ethylene-ethyl acrylate copolymer, powdery polystyrene, powdery higher fatty acids such as stearic acid, powdery potato starch, powdery corn starch, powdery polyvinyl alcohol, powdery ethyl cellulose and powdery carbon. The procedure for incorporating the pore-forming agent in the silica granules is not particularly limited provided that the mixing can be carried out without breaking of granules. The incorporation can be carried out, for example, by dry-mixing using a V-shaped blender. The procedure for molding a mixed powder of silica granule with a pore-forming agent is not particularly limited, and includes, for example, mechanical molding, hydrostatic molding, injection molding, extrusion molding and cast molding. Silica moldings have made only from a powdery silica raw material can be used, as they are, for the abrasive member of the invention. However, silica moldings made by using a binder or a pore-forming agent can be subjected to a post-treatment, for example, heat-degressing, firing or sintering and/or machining. The post-treatment procedure is not particularly limited provided that a mechanical strength sufficient for withstanding the polishing is given. Usually an organic binder and an organic pore-forming agent are incorporated in the raw material to enchance the moldability, and therefore, it is preferable that heat-degressing is carried out before the firing or sintering. The degreasing procedure is not particularly limited and includes, for example, heating in an air atmosphere, or heating under an inert gas atmosphere such as nitrogen, argon or helium. The pressure of the gaseous atmosphere may be chosen from a board range spanning from vacuum to a high pressure. Alternatively, to improve the moldability, it is possible that water is incorporated in the powdery raw material, and the molded product is dried before firing or sintering. The molded product from which a binder or pore-forming agent has been removed is preferably fired or sintered to improve its strength and durability of an abrasive disc made therefrom. Other means may also be employed. The process by which a soluble solid is charged within interconnecting minute pores of the thus-made silica molding to produce the abrasive member of the invention is not particularly limited. As examples of the process for charging a soluble solid, there can be mentioned a process wherein a vaporizable soluble solid is vaporized at a high temperature and/or under a reduced pressure, the vaporized soluble solid is passed alone or together with an inert gas through the interconnecting minute pores where the vaporized soluble solid is cooled to be thereby deposited within the minute pores; a process wherein the silica molding is impregnated with a solution or slurry of a soluble solid, and then the solvent is removed to produce a precipitate of the soluble solid; a process wherein the silica molding is coated with a solution or slurry of a soluble solid, and then the solvent is removed to produce a precipitate of the soluble solid; and a process wherein the silica molding is placed in contact with a solution or slurry of a soluble solid under a pressure, and then the solvent is removed to produce a precipitate of the soluble solid. The silica molding can be placed under a reduced pressure to deaerate the minute pores before charging a soluble solid therein. The solvent used for preparing the solution or slurry, the conditions for vaporization, and the temperature, pressure and time conditions for charging are not particularly limited, and known solvents and conditions may be employed. Abrasive Disc An abrasive disc is made by assembling the above-mentioned abrasive member and a supporting auxiliary. The supporting auxiliary used includes, for example, metal plates and other shaped parts. The material and shape of the supporting auxiliary, and the assembling procedure are not particularly limited. Usually the abrasive member is fixed to the supporting auxiliary by a procedure such as an adhering procedure using an adhesive, for example, an elastomer adhesive, a thermoplastic adhesive or a thermosetting adhesive, or a procedure of fitting the abrasive member into a recess formed on the supporting auxiliary. Since the abrasive member has interconnecting minute pores charged with a soluble solid, the abrasive member can be closely adhered to the supporting auxiliary, and the deviation of the abrasive member from the right position on the supporting auxiliary occurring due to loading or vibration can be prevented, which leads to enhancement of precision of polishing. When an adhesive is used for fixing the abrasive member to the supporting axuliary, care should preferably be taken so as to choose an adhesive causing no crazing or cracking of the abrasive member, such as an elastomer adhesive. The supporting auxiliary having the abrasive member fixed thereto is fitted to a polishing apparatus by fitting directly the supporting auxiliary to the polishing apparatus, or fixing the supporting auxiliary to a rotational member provided in the polishing apparatus by means of adhesion, embedding or screwing. The manner in which the supporting auxiliary is fixed or fitted to the polishing apparatus is not particularly limited, and varies depending upon the structure and shape of the supporting auxiliary. The number of the abrasive members fixed to the supporting auxiliary is not particularly limited, but preferably at least two abrasive members are fixed. When polishing is effected by using a disc having a plurality of abrasive members fixed to the supporting auxiliary in an arrangement such that a polishing liquid applied is discharged through drainage conduits formed between the adjacent abrasive members, the polishing rate can be increased. Further, the abrasive member is brought into uniform contact with the entirety of the material to be polished, and uniform polishing can be effectively conducted. When a disc having one abrasive member fixed to the supporting auxiliary is used, it is preferably that a conduit for draining a polishing liquid is formed on the polishing surface. The shape of the abrasive member is not particularly limited and includes, for example, a columnar pellet and a square pillar shaped pellet having a triangular or quadrilateral cross-section. The size of the abrasive member also is not particularly limited provided that a desired number of the abrasive members are capable of being fixed to a supporting auxiliary. Preferably the size is to an extent such that each abrasive member falls within a square area having a side length of 5 to 100 mm. Thus, an abrasive member of a columnar pellet shape preferably has a diameter of 5 to 100 mm and that of a square pillar shape preferably has a side length of 5 to 100 mm. Even if the size of the abrasive member is smaller than 5 mm, it has a good polishing performance, but, when an abrasive disc of a large size is used, too many abrasive members must be used to obtain polishing efficiency of an acceptable extent and thus the abrasive member has poor practicality. Even if the size of the abrasive member is larger than 100 mm, the abrasive disc exhibits a polishing performance of an acceptable extent provided that conduits for draining a polishing liquid are formed on the abrasion surface, but, the number of the abrasive members per unit area of a support must be small and it may be difficult to attain uniform polishing. The thickness (i.e., length perpendicular to the abrasion surface) of the abrasive member is not particularly limited, but is preferably in the range of 3 to 10 mm. At a thickness smaller than 3 mm, it is troublesome to exchange the abrasive member. In contrast, at a thickness exceeding 10 mm, it becomes difficult to uniformly apply a polishing liquid over the abrasion member. The distribution of the abrasive members in an abrasive disc is not particularly limited provided that the abrasive members are substantially uniformly distributed over the entire usable area of the surface of the
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—and state that engineering systems has made this list of “ilities” much longer. Why is that, and what would you consider to be the top four “ilities” of the engineering systems epoch? We analyzed the prevalence of these lifecycle properties in the engineering literature going back all the way to 1884. It became clear to us that the classical engineering “illities” such as quality, safety, and reliability were essential in making artifacts such as cars, power stations, trains, and telephones work reliably and predictably. Then, during and after World War II, we detect a major shift as we entered the Epoch of Complex Systems. During the war, it was essential to produce systems effectively at a large rate; therefore, the concept of scalability and usability of weapons systems was a major factor driving success on the battlefield. Usability and the field of human factors was invented and subsequently drove major design considerations for commercial products and systems. Starting in the 1970s concern over environmental impacts and interoperability of military systems, as well as the development of the internet, gave rise to new system properties such as sustainability and interoperability, which continue to be of major interest today. Also, due to the unpredictability and rate of uncertainty in today’s world, the desire for flexibility in systems continues to increase. One of the big challenges is to develop principles, methods, and tools for designing systems to be deliberately imbued with these properties with a level of rigor and predictability that is commensurate with that of the more traditional engineering properties. It also true that system properties that were once thought to have been masters, such as safety, must now be revisited due to the increasing sociotechnical complexity of today’s systems. What do you mean by “partially designed, partially evolved”? How does this concept apply to the MBTA? We usually think that engineers and designers have full control over their own inventions and creations. This may be true for smaller scale artifacts like watches, toasters, and cars; however, large scale engineering systems have lifetimes of decades or centuries. Over these long time periods the underlying demographics of users, economics, political imperatives, and natural environment may change in ways that were never considered by the original designers. Thus, parts of the system may be shut down or modified and new elements may be added in time. These patterns resemble more biological evolutionary processes rather than follow the initial plan laid out by a master designer. In terms of the MBTA (Boston’s local transit system) I would like to mention the creation of the Silver Line, an innovative bus line that uses mostly dedicated lanes and tunnels and serves the airport and rapidly evolving waterfront district in South Boston. This is intimately connected to the Central Artery (“Big Dig”) project that we discuss in the book. Did the original designers of Boston’s first electric street car in 1889 envision the Silver Line? Most certainly not. The system evolved over time as new elements were added to better serve the rapidly evolving city. What are the “enablers of success” as engineers address the engineering systems challenges that face humanity? This is a great question. The first thing that comes to mind is humility. Engineers must become aware not only of the intended consequences of their designs but also of the unintended consequences and the larger set of forces that will promote or inhibit the adoption of new technologies or “solutions” to pressing problems. Taking a broad socio-technical perspective, while preserving or deepening our understanding of the technical and social possibilities, is essential. The (re)visioning perspective is a useful initial starting point for organizing the thinking around large scale challenges of our time. There are examples of successes in taking this perspective, such as the transformation of IBM from a manufacturer of business machines to a provider of integrated business solutions and services; the innovative approach to transportation in cities such as Curitiba, Brazil; and the progress Australia has made in managing its scarce freshwater resources. Success depends on the barriers being broken down that today keep engineers, social scientists, and management scientists from teaming together in the most effective way to address the world’s problems. These barriers include the mental models those in various disciplines carry with them throughout their careers, the institutional obstacles that exist in academia and even in the business world, and the lack of understanding about what other disciplines might bring to the table (something we hope our book will make at least a small contribution to correcting). Using MIT as an example, how has the focus of engineering education changed over time? MIT has been and continues to be one of the leaders in engineering education. After the adoption of the engineering science approach after World War II (most of the big breakthroughs were led by trained physicists, not by engineers), engineering was refocused on the fundamentals of mathematics, physics, chemistry, and the other underlying natural sciences. Starting in the late 1980s and early 1990s, there was a realization that MIT needed to also directly impact industry and government practice, which led to the creation of new programs that integrated aspects of engineering with management and, to a lesser extent, with the social sciences. Degree programs such as System Design and Management (SDM), Leaders for Manufacturing (LFM)— now Leaders for Global Operations (LGO)—and the Engineering Systems Division (ESD) were driven by the need for a new and broader approach to engineering. Another example is the lifecycle-oriented curriculum known as CDIO (conceive-design-implement-operate) in Aeronautics and Astronautics, as well as the recent Gordon Engineering Leadership (GEL) program in the School of Engineering. One of the most difficult questions is how to provide a deep foundation in fundamentals while also exposing engineering students to the most important concepts (such as cost analysis, strategy, material selection, supplier sourcing, regulatory science) that often dominate engineering practice in the real world. Much work remains to be done, also at MIT. What kinds of changes (if any) do you think we need to make in engineering education? This may sound radical, but I think the time has come to fundamentally rethink the need for traditional departments. The distinctions between mechanical, electrical, chemical engineering , etc. are largely historical and a vestige of the past. Most of the systems and products being designed in the 21st century have a complex mix of mechanical, electrical, chemical, biological, and other cyber-physical elements and are designed for a large variety of human users. While engineers clearly must develop areas of deep expertise, it is not clear to us that this has to be done around the historically evolved stovepipes. It is interesting that none of the new universities that MIT is helping to get off the ground—such as Masdar Institute in Abu Dhabi, SUTD in Singapore, and SkTech in Moscow—have departments. They all have at their core an integrated modern curriculum that is centered on pillars or problem areas that map to large scale socio-technical challenges rather than to a set of clearly delineated governing equations such as the Navier-Stokes Equations (fluid dynamics), Maxwell's Equations (Electrical Engineering), or the Shannon-Hartley Law (Information Theory). Engineering education must change as was also articulated in the well-known Engineer 2020 report released by the National Academy of Engineering. In the book we argue that “Engineering education, which since its early days has enjoyed a rich history, today has begun to broaden from preparing students for technical careers to educating technically grounded leaders who will run complex systems and enterprises and establish new entrepreneurial startups.” We believe that the engineering systems concepts we discuss are an important step in that direction. February 14, 2012 The author of the classic philosophical treatment of love reflects on the trajectory, over decades, of his thoughts on love and other topics. A vision of architecture that transcends concerns of form and function and finds the connections between the architect's wish to design a beautiful world and architecture's imperative to provide a better place for society. A self-described failed filmmaker falls obsessively in love with her theorist-husband's colleague: a manifesto for a new kind of feminism and the power of first-person narration. A vision of architecture that includes sculpture, machines, and technology and encapsulates the history of the human species. February 08, 2012 A people of laughers, Langston Hughes has called his people. His poem “Laughers,” first published in Crisis in 1922 as “My People,” goes through a series of roles associated with African-Americans (singers, storytellers, dancers, but also dishwashers, cooks, and waiters), to conclude that they are laughers: “Yes, laughers…laughers…laughers— / Loud-mouthed laughers in the hands / Of Fate. “Yes, laughers…laughers…laughers” comes as a response to a doubtful question: “Laughers?” “Yes, laughers…” is the insistent answer, its insistence a function of the acknowledged irony of an African-American poet in 1922 describing his people as laughers. “I love myself when I am laughing” is also Zora Neale Hurston’s provocative statement, an attempt to claim membership with the same people of laughers. It is a response to Carl Van Vechten, who had taken a series of photographs of her laughing; but also to Hughes and his accusations that she had put on a “happy darkie” show and played the primitive. The sentence would be the site of Hurston’s recuperation by 1970s feminism, becoming the title of her 1979 collection published by Feminist Press. It condenses an “attitude” that brought Hurston intellectual annihilation in the 1930s and posthumous fame. A list of adjectives describes the “attitude” within different
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�钱 jiàqián price [C] 原价 yuánjià original price 讲价 jiǎngjià to haggle, discuss price 租价 zūjià rental 價 HǍI, sea; a family name [A] 海关 hǎiguān customs house; Customs [B] L5 海外 hǎiwài overseas, abroad [D] 上海 Shànghǎi Shanghai 海选 hǎixuǎn tryout 地中海 Dìzhōnghǎi Mediterranean Sea (MN) Every drop of water = sea BÙ, set, portion, part; department; a measure for vehicles; family name (rare) [A] 部分 bùfen portion, part [A] L4 部门 bùmén department [B] L5 部长 bùzhǎng department head [B] 部首 bùshǒu a "radical"—an element of the Chinese writing system HUÁNG, yellow; family name [A] L3 黄金 huángjīn "the yellow metal," i.e. gold [D] L5 黄豆 huángdòu soybean 黄河 Huáng hé the Yellow River 黄了 huángle (collquial) to have fallen through, have come to nothing (literally, "to have turned yellow") (田 10) ZǑNG, to add together; always; probably; surely [A] 总是 zǒngshì always [A] L3 总共 zǒnggòng altogether [C] L5 总得 zǒngděi must, have to [C] 总算 zǒngsuàn at last; on the whole [C] L5 总数 zǒngshù total, total amount [D] 連 LIÁN, to connect; continuously; including; company (military); even; family name [A] L4 连忙 liánmáng at once, promptly [B] L5 连连 liánlián (colloquial) repeatedly 连年 liánnián in consecutive years; year after year L6 连... 都(也) lián ... dou (yě) even (see Chao's Grammar, p. 766) [B] 總 ZHǏ, just, only; ZHĪ, a measure for animals, birds, boats; single [A] L3 Simplified form can be remembered as "mouth" + "eight." 只好 zhǐhǎo can do nothing but... [A] 只有 zhǐyǒu can do nothing but... [B] L4 只是 zhǐshì but; only [B] 只要 zhǐyào so long as [B] L4 只得 zhǐdé can do nothing but... [C] (zhī only) 隻 TÈ, be special [A] 特别 tèbié special, especially [A] L3 特点 tèdiǎn special feature [D] L4 特定 tèdìng be specifically designated [D] L6 特地 tèdì for a specific purpose [D] 特意 tèyì same as 特地 [D] (MN) A cow 牛 in the temple 寺 is special YÁNG, ocean; be foreign [B] The "water" radical gives the meaning, and "sheep" (yáng) gives the sound. 洋鬼子 yángguǐzi "foreign devil," foreigner (derogatory) 大西洋 Dàxīyáng the Atlantic 太平洋 Tàipíngyáng the Pacific 东洋 Dōngyáng Japanese, Japan YÚ, surplus; remainder [B]; (bookish) I, me; family name 其余 qíyú the rest of it [B] L5 余数 yúshù balance, remainder; complement of a number 余闲 yúxián spare time, leisure ("surplus; remainder" only) 餘 CHÚ, except; to divide (arithmetic); to remove [A] L5 除了... 以外 chúle...yǐwài other than... [A] 除外 chúwài except, excluding [D] 除夕 chúxī (on) New Year's Eve [D] L5 除去 chúqù in addition to; to remove n to; to removeAJIĀNG, river; family name [A] A sound-meaning compound, the "three-dots-water" radical helps with the meaning, but "工" no longer represents the sound in a good way. 长江 Chángjiāng the "long river," i.e., the Yangtse L4 江西 Jiāngxī Jiangxi (province) 江山 jiāngshān rivers and mountains; landscape; (by metonymy) nation QUÁN, complete, completely; all, the whole; family name [A] Distinguish from 金 "gold" (218, p. ). 完全 wánquán complete(ly); perfectly [A] L4 全部 quánbù the whole thing; completely L4 全面 quánmiàn overall; be comprehensive [B] L5 全力 quánlì with all your strength [D] 全心全意 quánxīnquányì wholeheartedly [D] (MN) All men are kings ZHĒNG, to argue, to fight [B] The character shows two hands struggling over an object (the hand on top is abbreviated). 争取 zhēngqǔ to work hard for [B] L5 争气 zhēngqì be determined; do your best to make a good showing [D] L6 爭 JÌNG, to clean, be clean; net (as opposed to gross); only, all [A] 干净 gānjìng be clean [A] L3 净得 jìngdé net profit 净重 jìngzhòng net weight (MN) Ice being fought (争) for is clean 淨 HÚ, barbarians; be foolish; beard, mustache; family name [B] 胡子 húzi beard, mustache [B] 胡说 húshuō to talk nonsense, to blather; Nonsense! Bunkum! [C] L5 胡来 húlái not know what you're doing; to act like a fool, make trouble; to blunder [D] (beard) 鬍 HÚ, lake [A] 湖北 Húběi Hubei (province) 湖南 Húnán Hunan (province) 江湖 jiānghú rivers and lakes; all over the country 江湖 jiānghu traveling con artists (entertainers, fake doctors, and the like) or itinerant performers and the like SHĀNG, quotient; commerce; merchant; family name [A] 商人 shāngrén businessman [A] 商船 shāngchuán merchant ship 商会 shānghuì chamber of commerce 进口商 jìnkǒushāng importer 商量 shāngliàng to negotiate L4 YÈ, business, profession, course of study; property; family name. BUSINESS radical (140) [A] 业 is thick foliage at the top of a tree, to suggest productive activity and prosperity. 商业 shāngyè business, commerce [B] L5 业余 yèyú spare time; amateur [B] L5 重工业 zhònggōngyè heavy industry [D] 業 MÍN, folk, people A][* 人民 rénmín the common people [A] 民主 mínzhǔ democracy, be democratic [B] L
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edge between the contacts on which the magnetoresistance $R$ is measured. Due to the interference of EMPs, generated by different contacts, $R$ oscillates as a function of the parameter $qL$, where $q(\omega,B)$ is the EMP wave-vector and $L$ is the inter-contact distance [@Kukushkin04a]. In strong magnetic fields $q(\omega,B)$ is proportional to $\omega B/n_s$, where $n_{s}$ is the electron density [@Volkov88Eng; @Mikhailov06b]. This leads to the $B$-periodic oscillations with the period $\Delta B\propto n_{s}/\omega L$. This theoretically predicted dependence was confirmed by the experiments [@Kukushkin04a; @Kukushkin05a]. EMPs have a much smaller damping, as compared to the bulk magnetoplasmons,[@Volkov88Eng; @Mikhailov06b] and, in contrast to the MIRO-ZRS effect, the EMP-related oscillations do not require low temperatures and samples with the very high electron mobility: they were observed at least up to $T\simeq 80$ K [@Kukushkin05a]. These EMP properties make the considered phenomenon especially promising for the creation of miniature microwave frequency-sensitive detectors and spectrometers. The frequency and density dependence of the oscillation period $\Delta B\propto n_{s}/\omega $, experimentally observed in the first papers [@Kukushkin04a; @Kukushkin05a], was confirmed in a later publication by Stone et al. [@Stone07]. However, in contrast to [@Kukushkin04a; @Kukushkin05a], they found that $\Delta B$ does not depend on the distance $L$ between the contacts. This contradiction remains unexplained so far; actually, it raises the question which length should be understood under $L$ in the discussed phenomenon. Notice that both in Refs. [@Kukushkin04a; @Kukushkin05a] and Ref. [@Stone07] $L$ was assumed to be equal to the distance $L_{ab}$ between the points $a$ and $b$ in Figure \[fig.1\](b), i.e. the points where the contact leads (made out of the 2DEG) touch the 2DEG channel. ![\[fig.1\](Color online) (a) A set-up of the device; the current flows from the contact 1 to the contact 2, the voltage is measured between the contacts 3 and 4; a magnetic field $B$ is perpendicular to the 2DEG plane. (b) Geometry of the metallic contact pads (hatched areas), contact leads (areas B) and of the 2DEG (area A); the black vertical element labeled as ‘g’ is the bridge-gate QPC. (c) The longitudinal resistance $R_{1,2;3,4}\equiv R$ at the microwave frequency $f=156$ GHz, temperature $T= 4.2$ K, the gate voltage $V_{g}=-1.39$ V and different values of the microwave power density.](Fig1a.eps "fig:"){width="0.49\columnwidth"} ![\[fig.1\](Color online) (a) A set-up of the device; the current flows from the contact 1 to the contact 2, the voltage is measured between the contacts 3 and 4; a magnetic field $B$ is perpendicular to the 2DEG plane. (b) Geometry of the metallic contact pads (hatched areas), contact leads (areas B) and of the 2DEG (area A); the black vertical element labeled as ‘g’ is the bridge-gate QPC. (c) The longitudinal resistance $R_{1,2;3,4}\equiv R$ at the microwave frequency $f=156$ GHz, temperature $T= 4.2$ K, the gate voltage $V_{g}=-1.39$ V and different values of the microwave power density.](Fig1b.eps "fig:"){width="0.39\columnwidth"}\ ![\[fig.1\](Color online) (a) A set-up of the device; the current flows from the contact 1 to the contact 2, the voltage is measured between the contacts 3 and 4; a magnetic field $B$ is perpendicular to the 2DEG plane. (b) Geometry of the metallic contact pads (hatched areas), contact leads (areas B) and of the 2DEG (area A); the black vertical element labeled as ‘g’ is the bridge-gate QPC. (c) The longitudinal resistance $R_{1,2;3,4}\equiv R$ at the microwave frequency $f=156$ GHz, temperature $T= 4.2$ K, the gate voltage $V_{g}=-1.39$ V and different values of the microwave power density.](Fig1c.eps "fig:"){width="0.9\columnwidth"} In this paper we investigate the EMP-related magnetoresistance oscillations in GaAs/AlGaAs quantum-well structures. Our work differs from the previous publications [@Kukushkin04a; @Kukushkin05a; @Stone07] in three essential aspects. First, the distance $L_{ab}$ in our samples ($\simeq 60$ $\mu$m) is almost two orders of magnitude shorter than in Refs. [@Kukushkin04a; @Kukushkin05a; @Stone07]. If the oscillation period was proportional to $1/L_{ab}$, we would observe more than ten times larger period $\Delta B$ than in Refs. [@Kukushkin04a; @Kukushkin05a; @Stone07]. But in our experiment $\Delta B\simeq 0.1-0.2$ T, which is close to the oscillation periods in [@Kukushkin04a; @Kukushkin05a; @Stone07]. Second, we have performed a more careful, quantitative comparison of our experimental data with the theory [@Volkov88Eng] and extracted the value of $L$ from the experimental data. It turns out to be of 1 mm scale which is much larger than $L_{ab}$ but is of order of the distance between the metallic contact pads measured along the edge of the 2DEG. Third, our samples were covered by a thin metallic gate forming a bridged-gate quantum point contact (QPC) [@Levin15]. Recently, in Ref. [@Levin15], we have shown (at $B=0$) that the Hall bars with the bridged-gate QPC demonstrate a two-three orders of magnitude higher sensitivity to the microwave irradiation than the structures with a traditional split-gate QPC. In the present work ($B\neq 0$, bridged-gate) we have found a much higher oscillation amplitude of the $B$-periodic oscillations ($\Delta R/R \simeq 7$) than in the ungated structures [@Kukushkin04a; @Kukushkin05a; @Stone07] or in structures with a split-gate QPC [@Dorozhkin05] ($\Delta R/R < 1$). Our results lead to a better understanding of the physics of the EMP-related magnetoresistance oscillations and pave the way to the creation of more efficient frequency sensitive detectors of microwave and terahertz radiation. Our specimens are narrow ($14$ nm) quantum wells with the electron density $n_{s} \simeq 10^{12}$ cm$^{-2}$ and the mobility of $\mu\simeq 1.3\times 10^{6}$ cm$^{2}$/V s at $4.2-1.4$ K. We measure the resistance on a conventional Hall bar patterned structure, which is designed for multi-terminal measurements. The sample consists of three $20$ $\mu$m wide consecutive segments of different length ($60$, $20$, $60$ $\mu$m), and eight voltage probes, see Figure \[fig.1\](a). High quality Ohmic contacts to a 2DEG are made using AuGeNi metalization followed by an annealing. Two thin metallic gates (bridged gate QPCs) are sputtered on the central parts of the left and right segments of the Hall bar. The middle segment was used to measure the resistance of the unpatterned 2D electron gas. Four devices were studied and the similar results were obtained. The measurements were carried out in a VTI cryostat with a waveguide to deliver MW irradiation (the frequency range 110 to 170 GHz, the power density $\sim 1-10$ mW/cm$^2$) down to the sample and by using a conventional lock-in technique to measure the longitudinal resistance $R=R_{1,2;3,4}$. Figure \[fig.1\](c) shows the magnetoresistance of the QPC at the temperature $T=4.2$ K, the frequency $f=156$ GHz and several values of the microwave power attenuation factor. The microwave irradiation leads to the strong suppression of the resistance at zero magnetic field [@Levin15]. At $B\gtrsim 0.7$ T (corresponds to $\omega_c\gtrsim \omega$) the resistance reveals the large $B$-periodic magnetoresistance oscillations. Figure \[fig.2\] illustrates the magnetoresistance at different (fixed) gate voltages varying from the open-contact regime ($R_{0}\lesssim h/e^{2}\simeq 25.8$ k$\Omega$) to the close-contact regime ($R_{0}\gg h/e^{2}$); here $R_{0}$ is the QPC resistance at $B=0$. The oscillation frequency shows no change
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, staffing levels are at a historic low, and several senior career positions have been vacant for years. Petersen is the third commissioner to quit since 2017, when Democrat Ann Ravel left before her term expired. Republican Lee Goodman resigned in February 2018, leaving the commission with only the barest quorum. The three remaining commissioners — Democrat Ellen Weintraub, Republican Caroline Hunter and independent Steven Walther — are all serving long past the point when their six-year terms expired. Weintraub, the longest-serving commissioner, has served 12 years past her term’s expiration. Petersen’s term expired in 2011. “It was a dysfunctional agency yesterday, and it continues being dysfunctional today,” said Sheila Krumholz, executive director of the Center for Responsive Politics. The lack of a quorum, she said, “makes it that much harder to get back to business if there were a willingness to negotiate and debate in good faith and come up with compromises and solutions.” Updated at 7 p.m. 1:02 PM? 6:23 AM How many minutes are there between 4:44 AM and 8:08 AM? 204 How many minutes are there between 8:56 PM and 7:06 AM? 610 What is 249 minutes before 2:51 AM? 10:42 PM How many minutes are there between 8:15 PM and 10:25 PM? 130 What is 612 minutes before 1:46 PM? 3:34 AM What is 557 minutes before 2:58 PM? 5:41 AM How many minutes are there between 4:17 PM and 9:37 PM? 320 What is 690 minutes before 5:28 AM? 5:58 PM How many minutes are there between 2:22 PM and 9:00 PM? 398 How many minutes are there between 1:36 PM and 6:54 PM? 318 What is 444 minutes before 4:41 PM? 9:17 AM What is 244 minutes before 11:59 PM? 7:55 PM How many minutes are there between 10:23 AM and 10:11 PM? 708 What is 669 minutes before 9:40 PM? 10:31 AM What is 520 minutes after 8:46 AM? 5:26 PM What is 111 minutes after 5:52 PM? 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irubin might offer cardiac protection via telomere targeting and more studies in this direction should be performed to test this possibility. Being the first study reporting this results and dealing with a relatively small sample size, additional similar studies are needed in order to confirm our findings. Besides, the current study design is characterized by a heterogeneous age range, and a larger sample size would compensate for its effects. In order to properly assess telomere dynamics in GS, a longitudinal approach following the same individuals over a prolonged time period, could be employed. It is of major importance to take a more in-depth look at the mechanisms behind the telomere length differences, and while our proposed model of reduced inflammation and cell turnover is very plausible, specific pathways remain to be uncovered. In addition, in order to properly assess the implications of the UCB-telomere length axis in CV health, a study investigating telomere length and Gilbert's Syndrome in CVD patients should be conducted. In conclusion, we could observe a further link between Gilbert's Syndrome, and possibly unconjugated bilirubin, and longevity, with emphasis on healthy aging. This work is important when considering bilirubin as a natural therapeutic in fighting cardio-metabolic diseases[@b14], as it emphasizes a long-term benefit on a cellular and molecular level. Materials and Methods ===================== Subject recruitment and sample preparation ------------------------------------------ This study was a case-control study (60 patients in each group) at a single centre in Austria. The study was performed at the Department of Clinical Pharmacology of the Medical University of Vienna and subjects (both control and GS) were recruited between 06/2014 and 01/2015 by direct advertising (bulletin boards, posters and flyers) and from the department's subject database. A total of 128 subjects (men and women) from the general population were recruited after a screening examination including liver enzyme values for γ-glutamyl transferase (γ-GT), alanine transferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), alkaline phosphatase, and blood count including reticulocytes, haemoglobin, and haematocrit. Inclusion criteria were normal liver function, absence of acute and chronic disease, and age between 20 and 80 years. Subjects with liver, heart or kidney conditions, haemolysis, diabetes, cholelithiasis, organ transplants, history of cardiovascular disease (CVD), cancer, smoking, excessive physical activity, and any medication that might alter liver metabolism as well as vitamin supplementation (4--5 weeks prior the blood sampling) were excluded. As an important diagnostic procedure, subjects were required to complete 400 kcal restricted fasting-protocol on the day preceding blood sampling, leading to increased serum UCB levels in absence of liver disease[@b37]. The criterion for group allocation (Gilbert's Syndrome or control group), was based on a fasting serum unconjugated bilirubin (UCB) concentration of ≥ or \<17.1 μmol/L respectively, measured by high-performance liquid chromatography (HPLC). Finally, subjects were stratified for the GS and control group and matched by age and gender to result in 40 men and 20 women in both groups, respectively, which reflects the occurrence of GS phenotype in the population[@b15]. The study was approved by the Ethical Committee of the Medical University of Vienna and the General Hospital of Vienna (\#1164/2014) and conducted in accordance with the approved guidelines by the Declaration of Helsinki. All subjects provided written informed consent. For each subject, fasting blood samples were collected on a single occasion, a maximum of two week following the screening test. Samples were drawn by venepuncture and a peripheral venous catheter, into EDTA, Li-Heparin and serum vacutainers (Vacuette K~2~EDTA and Z Serum Sep respectively, Greiner Bio-one GmbH). Samples were stored in cool and dark and subsequently processed, to yield aliquoted fractions thereof (whole blood, plasma, serum). The aliquots were stored at −80 °C until further analysis. Peripheral blood mononuclear cells (PBMCs) were isolated from EDTA blood using Leucosep separation tubes (Greiner bio one), by centrifugation according to the manufacturer's instructions and washed twice with ice-cold PBS. Cell count and viability was estimated using the Trypan blue exclusion test on a Countess Automated cell counter (Life Technologies). Cells were aliquoted in freezing medium (FBS + 10% DMSO) and cooled gradually to −80 °C using CoolCell (Biozym). Anthropometric measurements --------------------------- Standing height was measured without shoes to the nearest 0.5 cm with a commercial stadiometer (Seca, Hamburg, Germany), and body mass was evaluated with a digital scale (BWB 700, Tanita, Amsterdam, Netherlands) to the nearest 0.1 kg with subjects lightly dressed and barefoot. BMI was calculated as the ratio between the weight measured in kilograms and the square of the height measured in meters. To determine body composition (muscle and fat mass) Bioelectric Impedance Analysis (BIA) was used, which has been shown to provide reliable data of body composition in comparison to Dual-Energy X-ray Absorptiometry (DXA)[@b38]. BIA was performed in the morning after an overnight fast using a BIA Analyzer 2000-S (Data-Input GmbH, Darmstadt, Germany). Blood biochemistry ------------------ Liver enzymes (AST, ALT, γ-GT, LDH), iron, ferritin, transferrin, hemopexin, haptoglobin, homocysteine, hormones (estradiol, testosterone, TSH, triiodthyronine, thyroxin) were analysed in the routine core laboratory of the hospital (Olympus 5400 clinical chemistry analysers from Beckman Coulter) and measured on the day of blood sampling. Carboxy haemoglobin (CO-Hb) was measured directly from heparinized syringes, using a blood gas analyser ABL 700 (Radiometer, Brønshøj, Denmark). Unconjugated bilirubin measurement by HPLC ------------------------------------------ Serum samples for UCB measurement were stored in dark tubes, immediately after separation, as described previously[@b37]. Unconjugated bilirubin and heme were measured in serum samples, using a high-performance liquid chromatograph (Merck, Hitachi, LaChrom, Vienna, Austria) equipped with a photodiode array detector (PDA, Shimadzu,) and a Fortis C18 HPLC column (4·6 × 150 mm, 3 μm) with a phenomenex C18 HPLC guard column (4·0 × 3·0 mm). Sample preparation and analysis were performed as previously published[@b37]. Unconjugated bilirubin and haemin (both Frontier Scientific Europe, Carnforth, Lancashire, UK) served as external standards. Free bilirubin was calculated from serum UCB and albumin levels, using a formula kindly provided by Dr. Silvia Gazzin and Dr. Claudio Tiribelli. Gunn rat liver sample preparation --------------------------------- Hyperbilirubinaemic Gunn rats (20 in total, 9 males and 11 females), homozygous for a mutation in *UGT1A1*, and the same number of normobilirubinaemic Wistar rats, heterozygous for a mutation in *UGT1A1*, were obtained from Charles University in Prague (Prague, Czech Republic) and acclimatized in the breeding facility of the Medical University of Vienna (Himberg, Austria). The animals were housed in plastic cages (Macrolon type IV; Techniplast), under standard conditions (24 ± 1 °C, humidity 50 ± 5 °C, 12 h light/dark cycle) and fed with a standard diet (ssniff R/M-H Extrudat; ssniff Spezialdiäten) and *ad libitum* access to fresh water. The animals were sacrificed at the 7--8-week of age. The study was approved by the committee of animal experiments of the Austrian Federal Ministry of Science and Research (BMF-66.006/0008-II/3b/2011), and was carried out in accordance with the approved guidelines. Frozen liver samples, were used for DNA extraction. After thawing, not more than 20 mg rat liver was harvested and homogenized in ALT buffer (DNeasy Blood and Tissue Kit, QIAGEN) and Proteinase K. The samples were incubated at 37 °C overnight, until complete lysis. DNA extraction was completed the next day, using the kit manufacturer's standard protocol. Purity of the samples was determined by Nanodrop 2000c spectrophotometer (Thermo Scientific), and double stranded DNA concentration was measured by QuantiFluor® dsDNA System (Promega). For UCB measurement, cells and tissue samples were homogenized in HPLC mobile phase and prepared as described in the previous paragraph. Protein concentrations were measured using the Bradford reagent (Sigma Aldrich), as instructed by the manufacturer. DNA extraction from PBMCs and concentration measurement ------------------------------------------------------- DNA from human PBMCs was extracted from two million cells, using DNeasy Blood and Tissue Kit (QIAGEN), according to manufacturer's instructions. DNA concentration was measured using the QuantiFluor® dsDNA System (Promega), as a plate-based assay. A random subset of samples were measured using NanoDrop 2000c spectrophotometer (Thermo Scientific) and DNA integrity was estimated by agarose gel electrophoresis. Samples were stored at −20 °C, for no longer than 6 months prior to analysis. Absolute telomere length measurement in PBMCs by qPCR ----------------------------------------------------- Telomere length measurement was performed as described[@b39], with modifications. Shortly, SYBR Select
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those threads and blow your mind. * Know your prejudices and look for information that challenges them. My prejudices are that I think Windows is lame, that MacOS is infuriating, that Javascript is terrible, that vim is better than emacs, and emacs is better than IDEs, and object orientation is a failed paradigm. So I look out for articles that have a different point of view. I've learned that Microsoft has some really interesting technology, that Apple is infuriating even to its own users but it doesn't matter because they're sitting on the world's biggest pile of dollar bills, that Javascript is usually unnecessary but occasionally useful, that kakoune is even better than vim, and that nobody agrees about what object orientation even is. ~~~ Eire_Banshee "object orientation is a failed paradigm" uh... wtf? ~~~ Reedx Here's an explanation from Casey Muratori: [https://youtu.be/GKYCA3UsmrU?t=4m50s](https://youtu.be/GKYCA3UsmrU?t=4m50s) See also Mike Acton (Engine Director @ Insomniac Games): [https://www.youtube.com/watch?v=rX0ItVEVjHc](https://www.youtube.com/watch?v=rX0ItVEVjHc) ~~~ Zimahl You aren't going to get a lot of support for OO in places where it isn't really necessary like games, and especially games with single developers. At that point the management of data is on the developer. Essentially one is saying that if they fuck up the data, that's on them. OO is handy in enterprise software where there are lots of developers who may not understand why things are the way they are, they just need to do something. In big, complex systems where a lot of things are going on, if you give someone a noose, they will hang themselves. OO can protect data from some (of course not all) unintended consequences. ------ baccredited Save 25X your annual spending and you can retire. If you invest to earn 7%/yr (on avg), you can withdraw 4% forever. Read the book The Simple Path to Wealth, or the basics in this blog post. [http://www.mrmoneymustache.com/2012/01/13/the-shockingly- sim...](http://www.mrmoneymustache.com/2012/01/13/the-shockingly-simple-math- behind-early-retirement/) ~~~ kjullien Could anyone explain this a little for me, please? Does this mean you save 93% of your income and only use 7%? From the website, there is a graph that shows how many years you supposedly have to save for retirement but it does not take into account the actual amount you make. As a "junior" dev, if you save 97% of X peanuts you still have peanuts. ~~~ hellogoodbyeeee The 7% is referring to the rate of return on your investments. He is making the assumption that if you invest $100 in the stock market on January 1, then on Dec 31 your account will have $107 in it. This assumption is an average over many years. There is a common rule of thumb in the investing world that you can safely remove 4% a year from your investments and they will continue to grow. (7% return minus 4% withdrawals means you have 3% more in the account each year) It doesn't matter what your lifestyle is. If you are a junior developer who makes 80k a year and spends 50k a year, then you should save 25x50k=1.25mil and then you no longer have to work for a living. This process will take years or decades. ~~~ Z-Widwil Quick question. Is the 80k an example you threw out, or a reasonable amount for a junior dev to make? Specifically for a a mid-sized company in the States, outside of Silicon Valley. Currently working as a junior dev and the senior devs feel I'm making less than I should be. Which is much less than that 80k. The only caveat being that my employer is also paying for part of my tuition (up to a max of $5000 a year). Previously, this seemed like a decent increase with what I was making, but adding that 5k to my wage and I'm still nowhere near the 80k. I'm throwing out this comment as it seems like it would be beneficial to other junior devs to have a ballpark amount to shoot for. Obviously other factors play into this (e.g. healthcare, location, etc). This just seems like a decent play to ask without breaking taboo with local devs. ~~~ ptmcc It's obviously location dependent, but in most any booming US city (Seattle, Denver, Austin, etc.) a junior dev should be making at least 80k unless they are truly green. ------ dub I advise junior developers that there are primarily two difference between a junior and senior developer: 1) A senior developer is unafraid of not knowing things. When we join a new team or company, we're as lost as any junior developer joining them team. We ask as many questions as necessary to get our work done effectively, without shame or fear of looking foolish for not knowing things already. We are good at searching through unfamiliar codebases to figure out how they work. 2) A senior developer (or any productive person) is good at saying no. People will ask for more of your time than you can spare. You can gently but firmly say no, direct people elsewhere (delegate), or ask people to discuss with your manager whether more of your time can be allocated to help them. ~~~ donatj I would argue willingness to say no is what separates junior from senior. In my experience it actually leads to Juniors being abused a lot of times being given dumb projects someone should have said no to. Then code review rolls around and the seniors are like “what is this” and there’s a dumb fight. Lol. Maybe that’s just the places I’ve worked. ~~~ jcalabro I don't think you're the only one who has experienced this; we hired a couple of new grad programmers recently and they've really been put through the ringer. Not necessarily on dumb projects, but projects that one might categorize as urgent but not important. ------ TheAceOfHearts Try to sleep 8 to 9 hours every day. In this JRE podcast [0], Matthew Walker, a sleep expert, claimed that sleeping poorly can decrease your performance by 30%. Strive to maintain a good work-life balance. Burnout sucks. Your health and family are more important than work. A workplace that doesn't consider this to be the case is likely to be toxic. As for actual software development advice... Beware blanket statements. They can help you develop a low-resolution model so you don't suffer from paralysis, but real-world problems tend to be complex and messy. Here's an example: if you were building a traditional web app, many software engineers would probably suggest using something like PostgreSQL. That doesn't mean other database technologies don't have their place. However, PostgreSQL is able to adequately serve a large category of problems with relative ease, so it often makes for a sensible starting point. Once you become more familiarized with that domain you'll develop a higher-resolution model and you can begin to evaluate other technologies more effectively. Much of software engineering is about figuring out what tradeoffs to make. Another example in traditional web apps is using cookies for auth. Using cookies for this purpose is well documented and pretty much supported everywhere. There's plenty of known problems with using cookies for this purpose, but the alternatives also have their own set of issues to deal with. My final example: testing. Testing your code is great and it can be very useful, especially when refactoring or developing new features. But going for 100% code coverage is usually more trouble than it's worth. It's also very easy to end up writing a bunch of useless tests. You want to focus on the actual problem and not waste anyone's time. [0] [https://www.youtube.com/watch?v=pwaWilO_Pig](https://www.youtube.com/watch?v=pwaWilO_Pig) ~~~ Flow > Strive to maintain a good work-life balance. Burnout sucks. Your health and > family are more important than work. A workplace that doesn't consider this > to be the case is likely to be toxic. Good advice. It's likely burnout will really change you for the rest of your life if you don't react early enough. It's a bit sad when you realize you'll never again be that guy you grew up and
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The reply was that they had not heard, but they were of the opinion that they thought the same. [5] On hearing this all who were sitting at the tables said: 'What times they live in on earth now! What sad changes wisdom has undergone! It seems to have turned into foolish cleverness. The sun has set and is beneath the earth, diametrically opposite its noon position. How can anyone fail to know from the evidence of the people abandoned and then found in the forests, that this is what man is like if he receives no instruction? Surely he is what he is taught to be. By birth he is more ignorant than animals. He must then learn to walk and to talk. If he did not learn to walk, would he stand upright on his feet? And if he did not learn to talk, would he be able to utter any of his thoughts? Surely everyone is what he is taught to be, crazy if taught falsities, wise if taught truths? And if he is crazy from being taught falsities does he not imagine himself to be wiser than the man who is wise from being taught truths? Are there not foolish and deranged people who are no more human beings than those who were found in the forests? Are not those who have lost their memory like them? [6] 'From both these sets of facts we draw the conclusion that a man is not a man without instruction, and is not an animal either, but he is a form capable of receiving in himself what makes a man human, so that he is not born a man, but becomes one. Man has by birth a form such that he can be an instrument for the reception of life from God, with a view to being a subject into which God can put all good, and by union with Himself make blessed for ever. We perceive from what you say that wisdom at the present time is so far extinct or turned to foolishness, that there is total ignorance about the terms upon which human beings live as compared to those on which animals live. As a result, they do not know either anything about how a person lives after death. But those who are able, but unwilling, to know about this, and so deny its reality, as many of you Christians do, can be likened to the people found in the forests. It is not that they have become so stupid through being deprived of instruction, but they have made themselves stupid by relying on the fallacies of the senses, which are the darkness that conceals truths.' [7] But then someone standing in the middle of the Palladium and holding a palm-frond in his hand said: 'Please unravel this mystery. How could man having been created a form of God be changed into the form of a devil? I am well aware that the angels of heaven are forms of God, and the angels of hell are forms of the devil, and that these two are completely opposite forms, one of madness, the other of wisdom. Tell me, then, how could man created as a form of God pass from daylight into such a night as to be able to deny the existence of God and everlasting life?' The teachers replied one after the other, first the Pythagoreans, then the Socratics, and afterwards the rest. But among them there was a certain follower of Plato, who was the last to speak. His opinion, which was adopted, went like this. The people of the age of Saturn, the golden age, knew and acknowledged that they were forms for the reception of life from God, and consequently they had wisdom written upon their souls and hearts, so that they saw truth by the light of truth, and truths enabled them to perceive good by the pleasure of its love. 'But,' he said, 'as in the following periods the human race retreated from the acknowledgment that all the truths of wisdom and thus all the good of love they had was continually flowing in from God, they ceased to be dwelling-places of God, and then too they stopped talking with God and mixing with angels. For the interiors of their minds were diverted from their previous direction, which was being raised upwards by God towards God, and they were turned further and further aside, outwards to the world, and so directed by God to God by way of the world. Finally they were turned in the opposite direction, which is downwards towards oneself. Because a person who is inwardly turned upside down or away cannot look to God, people separated themselves from God and became forms of hell, and so of the devil. 'It follows from this that in the earliest ages people acknowledged with heart and soul that all the good of love, and so all the truth of wisdom, came to them from God, and also that this good and truth were God's in them, so that they were purely receivers of life from God; which is why they were called images of God, sons of God and born of God. But in the following ages people no longer acknowledged this with their heart and soul, but by some incorrect belief, later by historical faith and finally merely professing it with the lips. Acknowledging anything of this kind merely by professing it with the lips is not acknowledging it, and is in fact denying it at heart. [8] 'These facts enable us to see what wisdom is like on earth among present-day Christians. They can still be inspired by God as the result of a written revelation, while not being aware of the difference between man and an animal. Thus many people believe that if man lives after death, so too must an animal; or because an animal does not live after death, neither can man. Surely our spiritual light, which enlightens our mental vision, is in their case turned into thick darkness; and their natural light, which only enlightens the bodily vision, has become dazzling light to them?' [9] After this speech all turned to the two newcomers and thanked them for coming and bringing their report; and they begged them to carry back to their brethren a report of what they had heard. The newcomers replied that they would strengthen their people in their belief in this truth, that in so far as they attribute all the good of charity and all the truth of faith to the Lord and not to themselves, so far are they human beings and so far do they become angels of heaven. TCR 475. IV. SO LONG AS MAN LIVES IN THE WORLD, HE IS KEPT MIDWAY BETWEEN HEAVEN AND HELL, AND IS THERE IN SPIRITUAL EQUILIBRIUM, WHICH IS FREEDOM OF CHOICE. In order to know what freedom of choice is and the nature of it, it is necessary to know its origin. Especially from a recognition of its origin it can be known, not only that there is such a thing as freedom of choice, but also what it is. Its origin is in the spiritual world, where man's mind is kept by the Lord. Man's mind is his spirit, which lives after death; and his spirit is constantly in company with its like in the spiritual world, and at the same time by means of the material body with which it is enveloped, it is with men in the natural world. Man does not know that in respect to his mind he is in the midst of spirits, for the reason that the spirits with whom he is in company in the spiritual world, think and speak spiritually, while his own spirit thinks and speaks naturally so long as he is in the material body; and the natural man cannot understand or perceive spiritual thought and speech, nor the reverse. This is why spirits cannot be seen. But when the spirit of man is in company with spirits in their world, he is also in spiritual thought and speech with them, because his mind is interiorly spiritual but exteriorly natural; therefore by means of his interiors he communicates with spirits, while by means of his exteriors he communicates with men. By such communication man has a perception of things, and thinks about them analytically. If it were not for such communication, man would have no more thought or other thought than a beast, and if all connection with spirits were taken away from him, he would instantly die. [2] But to make it comprehensible how man can be kept midway between heaven and hell and thereby in spiritual equilibrium from which he has freedom of choice, it shall be briefly explained. The spiritual world consists of heaven and hell; heaven then is overhead, and hell is beneath the feet, not, however, in the center of the globe inhabited by men, but below the lands of the spiritual world, which are also of spiritual origin, and therefore not extended [spatially], but with an appearance of extension. [3] Between heaven and hell there is a great interspace, which to those who are there appears like a complete orb. Into this interspace, evil exhales from hell in all abundance; while from heaven, on the other hand, good flows into it, also in all abundance. It was of this interspace that Abraham said to the rich man in hell: Between us and you there is a great gulf fixed; so that they who would pass from hence to you cannot,
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you here now." "Then I'm glad," she said. "We've an opportunity to become reacquainted." Jaxyn glanced around to be certain they were alone. The rain pattered on the high roof, the noise loud enough to give them an added level of privacy. He lowered his voice. "What are you doing here, Lyna?" "Straight to the point, I see," she said. "Are you going to offer me a seat and some refreshments, or have me tossed into the lake?" "Well, if I thought you'd drown . . ." he said, a little testily, indicating she should take a seat on one of the couches in the nearest alcove. "What are you doing here?" "Looking for a home, Jaxyn." He studied her as she sat down, wondering if she was lying. It irked Jaxyn that his magical ability allowed him to move mountains, but couldn't help him at all in detecting when someone wasn't telling him the truth. "So why come here?" he asked, taking the couch opposite. "Syrolee's right next door." "I'm tired of Syrolee," Lyna said. "She's only interested in making things good for her family. Besides, her way of doing things is getting boring. But you . . . you seem to have carved a very nice niche for yourself here in Glaeba." "Not as nice as it could be." She looked at him with a puzzled expression. "Diala's here too," he explained. "Somewhat inconveniently married to the new king." With a resigned sigh, Lyna rose to her feet. "Then there's not much room for me here," she said. "Maybe I will pay Syrolee a visit in Caelum, after all." "You could marry me," he said, in a flash of inspiration. She stared down at him, shaking her head. "You cannot be serious." He nodded, smiling slyly, the idea forming even as he spoke. "I have acquired a bit of an unfortunate reputation around here, which is going to cause me trouble if I don't nip it in the bud. Taking a wife would do that." "What sort of reputation?" "The heir to the throne, with whom I used to be . . . _friends_ . . . was disinherited and put on trial for treason, but only to cover up the fact he was a sodomite. Glaebans are rather narrow-minded about things like that." Lyna didn't seem in the slightest bit surprised. But then why would she? She'd been Kentravyon's consort for a long time. Jaxyn, even at his worst, would be hard pressed to top some of the things her former lover had done. "Let me guess, you were the one who gave up your sodomite's nasty little secret?" Jaxyn nodded. It was a relief, sometimes, to talk to someone who made no pretence of being particularly noble or decent. "I run the risk of being tarred with the same brush unless I do something to persuade those who have a vested interest in seeing me tossed out of Glaeba, that I was the victim and not a willing participant in my former patron's games." "You mean you're afraid Diala will turn on you?" Lyna concluded with barely a moment to think about it. "That figures. I don't know why you thought you could trust her in the first place." "Circumstances thrust us together. I didn't set out to conspire with her deliberately." Lyna studied him thoughtfully. "So, in return for becoming the 'little woman' and removing any doubt about your sexual preferences, what do I get out of it?" "I'll make you Queen of Glaeba some day." "Hasn't Diala already got that job?" "While Mathu lives, she has. But my old friend, the sodomite-who-just-happens-to-have-a-claim-on-the-throne, has teamed up with Syrolee and Tryan in Caelum. We'll be at war within a matter of weeks." He smiled nastily. "All sorts of terrible accidents happen during wars." Lyna thought on it for a moment, and then nodded. Jaxyn wasn't really surprised. She probably had nowhere else to go. Since they'd banded together to put Kentravyon on ice—literally—Lyna had been at a loose end. She'd hung around on the fringes of Syrolee's clan mostly, during the last few High Tides, but she had no special loyalty to them . . . _Or does she? Is that what she's doing here? Has Tryan sent her to spy on me and Diala?_ Jaxyn wished he'd thought of that _before_ proposing to her . . . Still, there might be a way to turn this to his advantage, regardless of whose side Lyna was actually on. "Of course, you don't have to marry me right away. A betrothal will serve me just as well at this point." Lyna shrugged, unconcerned. "Just so long as I'm treated in the manner befitting the fiancée of the king's Private Secretary and the new Duke of . . . well, whatever it is you're the duke of now, you can take as long as you want." "Good, because I have a job that needs doing and I want someone I can trust to do it for me." "What job?" she asked, taking a seat again. "I need to find the wife of the former Duke of Lebec." "Why?" _Because I want her. Because the bitch defied me._ "Because I can use her to slow Stellan Desean down. He's urging Tryan to declare war on us because he thinks he has nothing to lose. I'd like to dissuade him of that notion." Lyna seemed to accept his reasons. And even Jaxyn had to admit, it sounded plausible. "What does this have to do with me?" "I want you to find her. She was in Ramahn, last I heard, but the trail's gone cold. I need you to find her and bring her back to Glaeba. Alive." "Won't that get in the way of our betrothal, dear?" He smiled and reached for her hand, kissing it gallantly. "You love to shop, Lyna, and nothing is too much for my beloved. Far be it from me to object if you want to search for the perfect wedding dress, even if it means travelling to the very ends of Amyrantha to find it." Lyna smiled. "You'll finance my _shopping_ expedition?" "Provided you bring home the parcel I want, money is no object." "Then we have a deal." She glanced past his shoulder at the entrance to the large atrium and then fixed her gaze on his. "There's a young man approaching us," she warned in a low voice. "Dark hair, wearing a coronet." "That will be Mathu, our new king. Kiss me." Lyna complied without argument, too skilled at the kind of deceit they were plotting to stand on ceremony. She kissed him with all the expertise a career as a whore and a few thousand years of practice had endowed her with. It was a very long time since Jaxyn had slept with Lyna. Her kiss made him regret that a little. "Well, aren't you the dark horse, Jaxyn Aranville!" Mathu exclaimed. They broke apart as the king stopped before them. Lyna—accomplished actress that she was—looked mortified to have been caught in such a compromising position. Jaxyn jumped to his feet, as if he was embarrassed beyond words. "Tides, I'm so sorry, your majesty . . ." "There's no need to apologise," the young man said with a wide grin. "Kylia told me you had a cousin come to visit, so I thought I'd come down and greet her personally. Never realised it was such a _close_ cousin." _Back-stabbing little bitch_ , Jaxyn thought, smiling at the king. Diala must have thought the same as Jaxyn had when he'd first been informed one Aleena Aranville was waiting in the atrium. She'd probably sent Mathu down here, thinking a real Aranville cousin had turned up and was in the throes of exposing Jaxyn as an impostor. "I'm more than my lord Aranville's cousin, your majesty," Lyna said, lowering her eyes with a demure curtsey. "We've been betrothed since we were children." Mathu punched Jaxyn on the arm playfully. "And you never mentioned her before? Shame on you, Jaxyn, for keeping your lovely fiancée a secret from us." He turned to Lyna. "You'll be staying here at the palace with us, of course, while you're visiting Herino? When's the wedding?" "Not for a while yet,
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There was a great murmuring in the crowd. "Unless yer 'eart is in your arse, Henry, I think you'll live to see another day," someone shouted. Henry whirled vainly trying to get a look, like a dog chasing its tail. The arrow had entered his left buttock cheek. Everybody could see that except him. "He shot me on purpose! Scoundrel!" He lunged for Simon, just as Ian lunged for him, to seize his arm and pull him back. "Calm yourself, lad. You oughtn't move overmuch." The arrow was well and truly in there, piercing right through the nankeen. "Aye, 'ave a rest, milord. Ye might not want to sit down to rest just yet, though," someone called, to general laughter. "Don't laugh!" somebody else shouted. " 'Tis a tragedy! He needs 'is arse for horse riding and sittin' at the pub chairs!" " 'E looks a bit like a weathervane, don't 'e, wi' that thing stickin' out o' 'im?" "That's a fine tail feather ye got there, m'lord! Ye look like me prize rooster!" "That there be a mighty funny-looking grouse ye've bagged there, Simon! Are you going to serve him up tonight?" Simon was wretched and white-faced with shock. His hands were trembling. "Stop it!" "Wot's it feel like, m'lord?" somebody asked the wounded Lord Henry. "It hurts!" he said, sounding surprised and martyred. And a bit intrigued. "Quite a bit, actually." He was doing an admirable job of not weeping, though it certainly looked as though he wanted to. And Ian knew the look of a man who would faint at any moment. "All right. That's enough," he barked. "Behave yourselves, gentlemen. And ladies," he added ironically with a swift and pointed look in Tansy Danforth's direction, whose gaze fled from his. Having been skewered before, though admittedly not with an arrow, Ian had a good deal of sympathy for it. "Is your father at home, Miss Pitney?" he called. Miss Amy Pitney's father was the town doctor. "The next town over, delivering a baby," she said regretfully. Ian sighed. His shoulders slumped. "Very well. I need ten tall and preferably wide volunteers . . ." AND THAT'S HOW, thanks to Miss Danforth, Ian found himself on his hands and knees carefully extracting an arrow from the large white hindquarter of a whimpering man. He was laid out, facedown, on a blanket. Rather like a grouse at a banquet, in fact. Ian's volunteers surrounded poor Lord Henry in a circle, backs to him, shielding him from the crowd. Nankeen was trimmed away neatly with a knife. Ian thrust his flask at him and instructed him to drink. He was given a rag with which to muffle his screams. And when the arrow was extracted, he was bandaged adroitly, because Ian had needed to do it dozens of times before during the war. Lord Henry didn't faint, but it was a near thing. "See the doctor this evening, if you can," Ian instructed the unfortunate, punctured Henry. Simon was white and wringing his hands, hovering on the outskirts of the circle. "I'm sorry. I'm so sorry, I'm so sorry, I'm so sorry. I didn't mean it, Henry, I'm so sorry." "No hard feelings." Harry was clipped but magnanimous in martyrdom. "Do you intend to shoot Duggan next?" Ian seized Simon by the elbow and pulled him aside. "How in the bloody hell did that happen? You're a better shot than that, Simon. Not as good as I am, naturally, but . . ." Ian knew how it had happened. Or why it had happened. He wanted to hear it from the man himself. Simon drew in a long breath and exhaled miserably, thrusting his hands deep into his pockets. "It's just . . . Ian, it's well . . . it's just . . . well, look at her," he said with muffled anguish. "I don't want to think the way I think, Ian. I really don't, but . . . look at her." Miss Danforth was wringing her hands, and a small crowd of young men were jostling each other for the honor of comforting her. From where he stood he could see the sun glance off the tears glittering in the corners of her big eyes. Her lush lower lip was trembling. She looked convincingly distraught, for someone so skilled at fomenting mayhem. Instantly, a half-dozen handkerchiefs were thrust out to her. She looked up, limpidly grateful. "Oh, she's pretty, all right," Ian said grimly. Behind them was a small knot of females, all of whose mouths had gone hard and horizontal and whose arms were crossed across their chests. Ian was reminded of wasps about to swarm. "Pretty? She's an angel!" Simon corrected, on an outraged hush. "So delicate and kind." "I'm not certain 'flattery' and 'kindness' are synonymous, Simon." "You can simply tell she has a heart of gold. Like her hair . . ." he said dreamily. Ian snapped his fingers beneath his nose, and Simon looked surprised. "You shot Lord Henry because she's an angel? I think you have your winged beings confused. It's Cupid who supposedly shoots arrows at people." "It was an accident! I was distracted. She was . . . she did . . . she did something to distract me, let's just leave it at that. She said archery was her favorite sport of all. That no one looked more like a Greek god than with a bow and arrow. And . . ." "And you . . . wanted to be a Greek god?" "Of course! Wouldn't you?" "But Cupid is the deity with arrows, and he's a fat little baby." Simon sighed with exasperation. "I think you're missing my point, Captain Eversea. What wouldn't you do for a woman like that? I care for my Josephine with all my heart. And yet . . ." Ian looked over there again, and found Miss Danforth looking his way, her eyes bright and silvery even from that distance. As if she wanted to see his opinion of her performance. He raised his hand in a subtle, sardonic little salute. She gave her head a little toss and graciously waved away the handkerchiefs thrust at her. Tilted her head up and offered up a tremulous smile to the crowd of men. On the outskirts of which stood Josephine Charing and Amy Pitney, who looked very willing to shoot her with an arrow. Ian was confident their aims would be terrible, and confident Miss Danforth would somehow escape, because if ever there was a survivor, she was one. It was an interesting question, however, that Simon had posed. Ian had done a lot to get a woman. Doing something foolhardy for a woman, in order to impress a woman, however, or earn her regard . . . never. Never had he made a fool of himself for a woman. Most of his family failed to recognize he had a pragmatic streak a mile wide. He'd never called anyone out and he'd never yet been called out, though the duke had cut it very fine. He'd never lost his mind over a woman, though he'd nearly lost his life over one and had certainly lost his dignity once. He'd never lost his mind to the point where he'd shot anyone with an arrow over one, that much was certain. "I think you need a drink, Simon. I think we all need a drink. And you best make sure Henry truly forgives you. Because the next competition is shooting, and I saw enough carnage during the war." PERHAPS IT HAD been all the stiff drinking they'd done to settle rattled nerves after the arrow incident, or perhaps it was because not enough drinking had been done in the wake of the arrow incident, but otherwise skillful marksmen were shooting shamefully wide of the mark. Over and over and over. And the mark target was an apple, glowing like a beacon at one hundred paces. They stepped up, one by one. Shot, one by one. And missed, one by one, again and again and again. The apple remained mockingly smooth and whole and gleamed improbably in the sunlight. "I don't know what the trouble is," Ian muttered. "At this rate, if we all needed to shoot our food in order to survive, we'd starve." He would have loved to shoot it. It was such an easy target, and he was such a skillful shot, and he felt trapped in a moment that was both dull and embarrassing. The apple needed shooting, for God's sake. Yet another hapless contestant stepped up to fire, and missed
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the sight of it makes her stop and stare. Her three year-old son has arranged the furniture with such precision that everything is in its proper place and not a single piece is missing. Except for one. The housekeeper doll – Mrs Mulligan. "Toby?" she calls, but there's no reply. She pokes her head around the sitting room door as she heads for the stairs, but the TV's off and Toby's not there. Emmie's angry howls continue unabated. She always sounds so angry, as if she's thinking: _How dare Mummy leave me alone up here like this?_ "Toby? Are you alright?" Still no reply. Emmie's angry protest is coming at her front two directions now – from the baby monitor in the kitchen as well as down the stairs. As she makes her way up, she catches a glimpse of the yawning doors of the doll's house again. She finds Toby in Emmie's room. He's peering through the bars of the cot at the screaming baby, chatting away quite happily. At first she thinks he's talking to the baby, or even talking to himself. Then she sees the housekeeper doll clenched tightly in his right hand and feels her throat constrict and her stomach knot in fear. The doll is watching Emmie with its black painted eyes, the never-changing expression of disapproval on its face. "Toby, what are you doing in here?" Jen demands, as she lifts the kicking, screaming infant out of her cot. The air is redolent with an unhappy marriage of diarrhoea and talcum powder. "Didn't you hear Mummy calling?" She lays Emmie down on her changing mat. Judging by the spreading yellow stain at the thigh of her babygrow, it's another squitty one. "Mrs Mulligan doesn't like Emmie screaming," he says with candid honesty. "But she's a baby," Jen says, wearily, "and that's just what babies do. And this one more than most," she adds under her breath. "Mrs Mulligan says that children should be seen and not heard," the toddler says. "Mrs Mulligan says we'd all be better off if the little blighter had never been born." She turns on him at that. "Toby! That's a horrible thing to say! I never want to hear you say such a horrible thing again!" With Emmie kicking her way out of the open nappy mid-change, Jen grabs Toby by the arms. "I never want to hear you talk about your little sister like that again!" Toby cries out in pain and drops the doll. It lands on the carpet, its head turned towards Jen, its painted features set forever in the same disapproving black scowl. Without thinking, she lashes out, kicking the doll out of the door and halfway across the landing. Toby starts to cry. "Go to your room!" she screams at him. Toby does as he's told, his little body shaking as it's wracked by his sobs. She turns back to the baby, fists clenched as she struggles to hold in her simmering rage. There's shit everywhere. Emmie's legs are covered in it, as is the changing mat. Some has even made it onto the wall. Jen gives in to her own scream of frustration, the baby's yells rising in response in animal panic. "Shut up! Shut up! Shut up!" she shrieks. And then she stops, exhaustion threatening to overcome her. Her heart's racing. She looks at her hands. She's shaking too. She just stands there for a moment, letting out her breath in a weary sigh. She doesn't know how long she stays like that, eyes closed, doing nothing, wishing the world away. But the world doesn't go away. Taking another deep breath, she opens her eyes and sets about clearing up the mess. "I MEAN, WHERE did he even hear language like that?" she says to Chris over dinner, as she twirls a piece of spaghetti onto her fork over and over and over. "Not on CBeebies, I take it." "I wish you would take this seriously, Chris." "Why? You seem to be taking it seriously enough for both of us." Her silence is reaction enough. "Look, you don't know what he might overhear at Nursery. They're caring people, sure, and I've got nothing against them, but they're common as." "It didn't sound like something they'd say." "Look, what is it you're really worried about here?" She hesitates before answering, still twisting the same piece of spaghetti around the tines of her fork. "I guess I'm worried he might try to hurt her." "Emmie?" "Of course, Emmie! Who else would I mean?" "Alright," he counters defensively. "But come on, be serious. Do you really think that's likely to happen?" She says nothing. Chris looks at her, an expresson of burgeoning anxiety on his face. "Clearly you do." She meets his gaze at last, her tired eyes wide with fearful doubts of her own. "Look, here's what I think you should do. Call Doctor Pomeroy in the morning." "Great! So you think I'm going mad." "No! No, I don't. Not at all. But what harm could it do just to have a chat about things?" Jen turns her attention back to the congealing meal on her plate. "Everything was alright until she brought that bloody doll's house round." "Now, come on, Jen. You got ill before and it didn't have anything to do with a doll's house." "I was right. You _do_ think I'm going mad." She pushes her plate away from her with a clatter of cutlery. "Look, let's not do this again. Not tonight. I've had the day from Hell and –" "And you think I haven't?" "I was just going to say we're both tired, so let's open a bottle of wine and relax. Watch some TV, nothing more heavy than that, and let's see where the evening takes us. No pressure." "That's your answer to everything, isn't it?" "What?" "Alcohol!" Chris slams his hands down on the breakfast bar and gets up from his seat. "I can't talk to you when you're like this." "Where are you going?" she asks, suddenly consumed by overwhelming dread. He's already in the hall putting on his shoes. "Out." "But we haven't finished supper." "Oh, I rather think we have, don't you?" He picks up his keys from the shelf by the door and is gone, slamming the door behind him. "I'M WORRIED ABOUT you, Jennifer dear," comes her mother's voice down the phone line later that evening. Jen takes a moment to wipe her nose on the balled-up tissue she's been using to wipe away her tears, as she struggles to compose herself. "Don't be," she manages between sniffs. "I'm alright. Really I am. It's just that I've been so tired and then Chris storming out earlier... I just wanted somebody to talk to." "Are you sure, Jen? I don't want you to take this the wrong way, but this isn't your old condition coming back, is it?" "If we're going to rake over the past, Mum, can we at least call it by its proper name? It's not 'my old condition' or 'the baby blues.' It's called postnatal depression. But I'm not depressed!" "Couldn't you just give that nice doctor of yours a call in the morning? You know, the one you saw last time. What was his name?" "Doctor Pomeroy. And no, I'm not going to call him in the morning, because I am not suffering from postnatal depression." "Do you want me to come over, Jennifer? I'm supposed to be going over to Tommy and Sheila's but it's nothing I can't cancel. I mean we've had it planned for weeks now, but if you want me to come over, I'll give them a buzz and tell them I can't make it." "No, Mum, it's alright. I'm fine. Honestly, I'll be okay." "Alright, then, if you're sure. But just give Doctor Pomeroy a call for me, will you dear?" "'Bye Mum." "'Bye, dear." She puts down the phone quickly before the tears start again. IT'S GONE MIDNIGHT before Chris comes home again. The time it takes him to open the door and the way he stumbles about downstairs, in a vain effort to be quiet, tells her he's drunk. He'll regret it in the morning. She listens as he makes himself some toast and then hears the muffled tones of the television as he moves into the sitting room. He doesn't
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\_\^r\_r+v \_r \^r\_r+\^r\_r(\_v\^2+\_r v+ +)+\^\_ , \[eq:dpi-tau\]\ d\_\^\_r &=& v \_\^r\_r+\_r \^r\_r+\^r\_r (\_v++) + \^\_ . \[eq:dpi-r\] In addition, one needs the following \^[r]{} u\^[r ]{} &=& - \_r u\^r- u\^r D\_u u\^r + (u\^)\^2 \_u ,\[eq:nablar-ur\]\ r\^2 \^ u\^ &=&- +\_u , \[eq:nablavph-uph\]\ \^2 \^ u\^ &=&- +\_u , \[eq:nablav-uv\]\ \_u\_u\^&=&d\_u\^= \_u\^+\_r u\^r++ , where $\pi^r_\tau=-v\, \pi^r_r$ and $\pi^\phi_\phi=-\pi^\varsigma_\varsigma-(1-v^2) \pi^r_r$ which are a consequence of the transversality of the shear-stress tensor, $u_\mu \pi^{\mu\nu}=0$. This system of equations has to be closed by providing an equation of state (EoS), e.g. $P_{\rm eq}=P_{\rm eq}(\varepsilon_{\rm eq})$. For the numerical results presented in the body of the manuscript, we use the lattice-based EoS specified in Sec. \[sec:eos\]. Viscous hydrodynamics freeze-out {#viscous-hydrodynamics-freeze-out .unnumbered} -------------------------------- The distribution function on the freeze-out hypersurface can be computed assuming that there is a linear correction to the equilibrium distribution function [@Teaney:2003kp] f(p,x)=f\_[eq]{} . \[eq:vfreeze\] Using tensor transformations applied to Eq. (\[eq:ptl-mom\]) the components of the four-momentum in polar Milne coordinates are p\^&=&p\^t-p\^z=m\_(y-) ,\ p\^r&=&p\^x +p\^y=p\_(-) ,\ p\^&=&-p\^x+p\^y=-(-) ,\ p\^&=&-p\^t+p\^z=(y-) . \[eq:p-con\] Using Eq. (\[eq:pi-mat-1\]) and expanding $p_\mu p_\nu\pi^{\mu\nu}$ in polar Milne coordinates one has p\_p\_\^&=&p\_\^2\^+p\_p\_r\^[r]{}+p\_r p\_\^[r]{}+p\_r\^2\^[rr]{}+p\_\^2\^+p\_\^2\^ . \[eq:expansion1\] As a result, one obtains p\_p\_\^=&-&()(m\_v (y-)-p\_(-))\^2\ &-&\^\_p\^2\_\^2(-)-\^\_m\^2\_\^2(y-) . Factorization in non-conformal anisotropic hydrodynamics {#app:factorization} ======================================================== In the case that the particles comprising the system are massive, conformality is broken and it is no longer possible to multiplicatively factorize the energy density and pressures as in Eqs. (\[eq:ed\])-(\[eq:pz\]) [@Martinez:2012tu; @Florkowski:2014sfa; @Florkowski:2014bba; @Nopoush:2014pfa]. For a system with constant mass $m$ one has instead [@Nopoush:2014pfa] &=& [H]{}\_3(,,) \^4 ,\ P\_T &=& [H]{}\_[3T]{}(,,) \^4 ,\ P\_L &=& [H]{}\_[3L]{}(,,) \^4 , \[eq:massivet\] where ${\boldsymbol\alpha} = (\alpha_x,\alpha_y,\alpha_z)$, $\hat{m} \equiv m/\lambda$, $\hat{p} \equiv p/\lambda$, and the constraint $\Phi = \frac{1}{3} \sum_i \alpha_i^{-2} - 1$ with $i \in \{x,y,z\}$ is implicit. The functions ${\cal H}_3$, ${\cal H}_{3T}$, and ${\cal H}_{3L}$ are given by \_3(,,) && \_x \_y \_0\^[2]{} d \_\^2 \_0\^d \^3 f\_[eq]{}() [H]{}\_2(, ) , \[eq:h3gen\]\ [H]{}\_[3T]{}(,,) && \_x \_y \_0\^[2]{} d\_\^2 \_0\^d \^3 f\_[eq]{}() [H]{}\_[2T]{}(, ) , \[eq:h3tgen\]\ [H]{}\_[3L]{}(,,) && \_x \_y \_0\^[2]{} d \_\^2 \_0\^d \^3 f\_[eq]{}() [H]{}\_[2L]{}(, ) , \[eq:h3lgen\] with $\alpha_\perp^2 \equiv \alpha_x^2 \cos^2\phi + \alpha_y^2 \sin^2\phi$, $\hat{p} = |\hat{\bf p}|$, $\tilde{N} = N_{\rm dof}/(2\pi)^3$ with $N_{\rm dof}$ being the number of degrees of freedom, and the functions ${\cal H}_2$, ${\cal H}_{2T}$, and ${\cal H}_{2L}$ are given by \_2(y,z) &=& ( (1+z\^2) \^[-1]{} + ) , \[eq:H2m\]\ [H]{}\_[2T]{}(y,z) &=& , \[eq:H2Tm\]\ [H]{}\_[2L]{}(y,z) &=& . \[eq:H2Lm\] ![The ratios (a) $r_\varepsilon$, (b) $r_T$, and (c) $r_L$ as a function of $\hat{m} = m/\lambda$ for three different values of the pressure anisotropy $P_L/P_T = \{0.1, 1, 10\}$ corresponding to $\alpha_z = \{0.65499, 1,5.4631\}$.[]{data-label="fig:rats"}](erat "fig:"){width="0.32\linewidth"} ![The ratios (a) $r_\varepsilon$, (b) $r_T$, and (c) $r_L$ as a function of $\hat{m} = m/\lambda$ for three different values of the pressure anisotropy $P_L/P_T = \{0.1, 1, 10\}$ corresponding to $\alpha_z = \{0.65499, 1,5.4631\}$.[]{data-label="fig:rats"}](ptrat "fig:"){width="0.33\linewidth"} ![The ratios (a) $r_\varepsilon$, (b) $r_T$, and (c) $r_L$ as a function of $\hat{m} = m/\lambda$ for three different values of the pressure anisotropy $P_L/P_T = \{0.1, 1, 10\}$ corresponding to $\alpha_z = \{0.65499, 1,5.4631\}$.[]{data-label="fig:rats"}](plrat "fig:"){width="0.32\linewidth"} Since ${\cal H}_3$, ${\cal H}_{3T}$, and ${\cal H}_{3L}$ depend on many variables, we first restrict ourselves to the case that $\alpha_x = \alpha_y$ which is appropriate for the case of 1+1d dynamics considered in the body of the text. In addition, since, in the body of the text we assume $\Phi=0$, we also assume this here. With these assumptions, one can write $\alpha_x$ in terms of $\alpha_z$ [@Nopoush:2014pfa] \_x\^2 = . In order to test the degree to which the conformal factorization occurs in the massive case, we define three ratios r\_&& ,\ r\_T && ,\ r\_L && , where ${\cal R}$, ${\cal H}_{Tx}$, and ${\cal H}_L$ are defined in Eqs. (\[eq:rfunc\])-(\[eq:hlfunc\]). The factors of ${\cal H}_3({\bf 1},0,\hat{m})$, ${\cal H}_{3T}({\bf 1},0,\hat{m})$, ${\cal H}_L({\bf 1},0,\hat{m})$ are introduced in the denominator in order to compensate for the trivial mass dependence of the EoS in the isotropic case. If these ratios are equal to one, then there is perfect factorization of the diagonal components of the energy momentum tensor and the size of the deviation from unity is indicative of the degree to which factorization is broken in the non-conformal case. We present our numerical evaluation of these three ratios in Fig. \[fig:rats\]. As can be seen from the three panels, as long as $0.1 < P_L/P_T < 10$ and $\hat{m} < 1$, the maximum correction to all of these ratios is approximately 5%. For the case of oblate
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, and we start coming to the end of ourselves. Only when this happens do we reach out for the help God alone can provide. Weak and needy people finding their hope in Christ's grace are what mark a mature relationship. The most dangerous aspect of your relationships is not your weakness, but your delusions of strength. Self-reliance is almost always a component of a bad relationship. While we would like to avoid the mess and enjoy deep and intimate community, God says that it is in the very process of working through the mess that intimacy is found. Timothy S. Lane and Paul David Tripp # January 17 Psalm 34 God's Word invites change. In the Bible's vivid picture, we "turn" to our Father, Savior, and Comforter. He works in us toward one goal: change. The central dynamic of the Christian life has this FROM...TO... movement. Repentance is not only how we start the Christian life; it is the Christian life. Faith does new transactions and conversations with God. Love does new actions and choices on the stage of life. When God calls, you listen. When he promises, you trust and talk back to him in your need. When he loves, you love. When he commands, you obey. You aim your life in a new direction by the power of the Holy Spirit. In every case, you turn. The patterns, themes, and tendencies of our lives are what we see when, figuratively, we view our lives from the observation deck of the Empire State Building. From one hundred floors up, Manhattan and the Hudson River spread serenely before you. But the action and noise of life happens at the corner of Fifth Avenue and 34th Street, and when we take the Lincoln Tunnel home to Hoboken. The big stories of our lives are worked out in a running series of small scenes. This is how God has made it to be. He works for a turn-the-world-upside-down reorientation and redirection. Change takes place in the watershed moments and decisive incidents of everyday life. David Powlison # January 18 Ecclesiastes 12:1–14 He is God and we are not. When you observe life and listen to wise people, you will quickly find that we simply can't invest our hopes, dreams, and love in the self because it was never intended to carry such freight. For that matter, there is nothing created that was intended to sustain such hopes. Creation is to be enjoyed, but we don't put our trust in it. The only alternative is God himself. The Teacher in the book of Ecclesiastes tries to save us time in our search for meaning and purpose. He tells us that he tried learning, laughter, great projects, unbridled sexual pleasure, money, music, and children. None of them, when they were elevated to his life's purpose, led to anything but despair. He could not find his purpose in the created world. After briefly envying an ordinary life of honest toil, good friends, food, moderate drink, and doing right, he comes to his answer—his purpose. "Now all has been heard; here is the conclusion of the matter: Fear God and keep his commandments, for this is the whole duty of man" (Ecclesiastes 12:13). The fear of God is how we respond to the fact that God is greater than we are—different from us—in all things. His beauty is greater. His wisdom is greater. His love is greater. And, yes, his anger is greater. Simply put, he is God and we are not. Edward T. Welch # January 19 Ephesians 1:15–23 Glorify. Since Scripture has so much to say about our purpose, it has a rich vocabulary for it. One particularly fine word is the word glorify. We are created to glorify God. In the book of Ephesians, Paul reminds us three times in his introduction that we live "to the praise of his glory" (Ephesians 1:6, 12, 14). When we think of glory, we think of something big, beautiful, and obvious. "What a glorious sunset this evening!" "Her aria was simply glorious." To glorify God means to have our lives make him obvious and beautiful. We want him to be famous. We want to draw attention to the glorious God who loved us, and we do that by trusting him and loving others. In 1646 over one hundred clergymen met, at the request of the English king, to develop a summary of biblical teaching that would be suitable to guide the church. In the children's catechism (which is a series of questions and answers), the first question had to do with our purpose: "What is the chief end of man? Man's chief end is to glorify God and enjoy him forever" (The Westminster Shorter Catechism). They are right. This is our purpose. It is not about us; it is about God and his purposes. What could be bigger and grander than that? Edward T. Welch # January 20 Exodus 16:1–12 "If only we had died by the Lord's hand in Egypt! There we sat around pots of meat and ate all the food we wanted, but you have brought us out into this desert to starve this entire assembly to death." This is not exactly a model prayer. There is complaining, grumbling, self-pity—all the things that can drive us crazy about other people. Given such self-centered insolence, you would at least expect God to say, "I'm not listening until you ask nicely." But this is not an invented story where the god is like us. This is the God. "The Lord said to Moses, 'I have heard the grumbling of the Israelites. Tell them, "At twilight you will eat meat, and in the morning you will be filled with bread. Then you will know that I am the Lord your God"'" (Exodus 16:9–12). This response goes against all our expectations. God truly is not like us. It is as if God says to us, "Let me remind you of how I listen and see if you think I could listen even to you." Then he recounts stories of adulterers like King David, murderers like the apostle Paul, and grumblers like newly delivered Israel. If he hears and loves them, he will hear and love us. The lesson is clear: He doesn't hear because of us and the quality of our prayers. He hears because he is the God Who Hears. Edward T. Welch # January 21 Galatians 1:6–9 Self-focus is dangerous. The most dangerous kinds are those that take on the form of the good things of the kingdom of God. Christ warns: "Watch out for false prophets. They come to you in sheep's clothing, but inwardly they are ferocious wolves" (Matthew 7:15). Paul writes: "Such men are false apostles, deceitful workmen, masquerading as apostles of Christ. . . . Satan himself masquerades as an angel of light. It is not surprising, then, if his servants masquerade as servants of righteousness. Their end will be what their actions deserve" (2 Corinthians 11:13–15). In Galatians 1:6–7, Paul warns against a false gospel that wears the costume of the true gospel. Notice the strong language: "I am astonished that you are so quickly deserting the one who called you by the grace of Christ and are turning to a different gospel—which is really no gospel at all. Evidently some people are throwing you into confusion and are trying to pervert the gospel of Christ." The kingdom of self is most dangerous when it takes on the contours of the kingdom of God. It is possible for you to be convinced that you are living for the transcendent glories of the kingdom of God when you are, in fact, living for yourself. The most dangerous idols are those that are easily Christianized. Selfishness is most dangerous when it masquerades as service. Self-focus is most powerful when it dons the costume of love. Paul David Tripp # January 22 Genesis 1 God created the universe to display his glory, to make visible his invisible qualities—his eternal power and divine nature. What you see in nature tells you something about him. When you look at a tree's countless leaves, you're meant to understand something about God's infinity, his beauty, his creativity, and his abundant life. And then you are meant to bow in worship as you imagine what God conveys to you through an entire forest! In Genesis 1, we witness the unfolding of his glory. God says, "Let there be light," and the angels gasp, not just because they see light, but because the existence of light reveals God more clearly. God separates the waters and the gasps grow louder as more of their Maker is revealed. At each successive stage, the angels see more and more of their God, and they praise him with greater knowledge and insight. And then, at the pinnacle of creation, to reveal himself most clearly and brightly, God makes humans in his image. The angels simply marvel. Here, among all the wonders and majesty of the universe, stand the best reflection of who and what God is. Here was glory so real, so tangible, that the inconsequential planet floating in the heavens blazed like a beacon across the universe, proclaiming not humanity's worth and value, but the Holy Creator
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HAS JUDGE WAIT EVER ATTENDED ANY SSPF FUNCTIONS in addition to the May 11, 2012 dinner? #7: HAS JUDGE WAIT MADE ANY OTHER FINANCIAL CONTRIBUTIONS to SSPF aside from the $65 or $55 May 11, 2012 dinner? #8: HAS JUDGE WAIT EVER BEEN A MEMBER OF THE SSPF? #9: ARE ANY MEMBERS OF JUDGE WAIT’S CLOSE FAMILY active members of the SSPF such as to give the appearance of impropriety? NYRA- How Safe a Bet? Who ARE these guys? I've been a journalist since Watergate and an American by the grace of God. The only thing that disappoints me more than America's political decline is the absolute collapse of reliably solid investigative journalism. Nothing short and senseless here. No Britney or Lohan. NOR will you find any ridiculous ravings of a conspiracy quack. What I DO HAVE are sources and the time to read newsites from other countries. I don't text and I don't use emoticons. Words are far too precious. Serious analysis is all too rare./** * * WARNING! This file was autogenerated by: * _ _ _ _ __ __ * | | | | | | |\ \ / / * | | | | |_| | \ V / * | | | | _ | / \ * | |_| | | | |/ /^\ \ * \___/\_| |_/\/ \/ * * This file was autogenerated by UnrealHxGenerator using UHT definitions. * It only includes UPROPERTYs and UFUNCTIONs. Do not modify it! * In order to add more definitions, create or edit a type with the same name/package, but with an `_Extra` suffix **/ package unreal.googlearcoreservices; /** A function library that provides static/Blueprint functions for Google ARCore Services. **/ @:umodule("GoogleARCoreServices") @:glueCppIncludes("GoogleARCoreServicesFunctionLibrary.h") @:uextern @:uclass extern class UGoogleARCoreServicesFunctionLibrary extends unreal.UBlueprintFunctionLibrary { /** Configure the current Unreal AR session with the desired GoogleARCoreServices configuration. If there is an running AR session, the configuration will take effect immediately. Otherwise, it will take effect when the next AR session is running. @param ServiceConfig The desired GoogleARCoreServices configuration. @return True if GoogleARCoreServices is configured successfully. False if the configuration failed to apply. **/ @:ufunction(BlueprintCallable) static public function ConfigGoogleARCoreServices(ServiceConfig : unreal.googlearcoreservices.FGoogleARCoreServicesConfig) : Bool; /** Creating and hosting a CloudARPin and return it immediately. Note that this function only start the hosting process. Call GetARPinCloudState to check if the hosting is finished or failed with error. **/ @:ufunction(BlueprintCallable) static public function CreateAndHostCloudARPin(ARPinToHost : unreal.augmentedreality.UARPin, OutTaskResult : unreal.Ref<unreal.googlearcoreservices.EARPinCloudTaskResult>) : unreal.googlearcoreservices.UCloudARPin; /** Creating and Resolving a CloudARPin and return it immediately. Note that this function only start the acquiring process. Call GetARPinCloudState to check if the acquiring is finished or failed with error. **/ @:ufunction(BlueprintCallable) static public function CreateAndResolveCloudARPin(CloudId : unreal.FString, OutTaskResult : unreal.Ref<unreal.googlearcoreservices.EARPinCloudTaskResult>) : unreal.googlearcoreservices.UCloudARPin; /** Remove the given CloudARPin from the current ARSession. **/ @:ufunction(BlueprintCallable) static public function RemoveCloudARPin(PinToRemove : unreal.googlearcoreservices.UCloudARPin) : Void; /** Get a list of all CloudARPin in the current ARSession. **/ @:ufunction(BlueprintCallable) static public function GetAllCloudARPin() : unreal.TArray<unreal.googlearcoreservices.UCloudARPin>; } Abstract: The aim of the present study was to identify chemical composition and evaluate antimicrobial effectiveness of the essential oil of Cistus ladanifer var. maculatus Dun. The essential oil of C. ladanifer’s leaves was obtained by hydro-distillation and analyzed by gas chromatography coupled with mass spectrometry (GC/MS). 28 compounds were identified, representing 88.67% of the total constituents. The main compound was identified as Verticiol (18.16%), followed by Camphene (17.70%), γ-Gurjunene (7.15%), n-Butylcyclohexane (5.95%) and Bornyl acetate (5.86%). The oil was found to be rich in Monoterpene Hydrocarbons (32.05%), followed by Diterpenic alcohol (18.16%), Oxygenated hydrocarbons (13.27%), Sesquiterpene hydrocarbons (12.40%), Monoterpenic ester (5.86%), Cyclic ether (4.36%) and Oxygenated sesquiterpenes (2.57%). Antimicrobial activity of the essential oil of C. ladanifer was tested against two Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis) and two Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria, and three fungi (Candida albicans, Trichophyton rubrum and Aspergillus niger), by the microdilution method. In fact, strong inhibitory and bactericidal effect has been shown against all tested Gram-positive and Gram-negative bacteria. Indeed, strongest inhibitory and fungicide effect was exerted against the yeasts and molds studied. It seems following this study that the essential oil of C. Ladanifer has very significant antimicrobial activity, it shows a broad spectrum covering Gram-positive, Gram-negative bacteria, yeasts and fungi. AUTHORS ABSTRACT The aim of the present study was to identify chemical composition and evaluate antimicrobial effectiveness of the essential oil of Cistus ladanifer var. maculatus Dun. The essential oil of C. ladanifer’s leaves was obtained by hydro-distillation and analyzed by gas chromatography coupled with mass spectrometry (GC/MS). 28 compounds were identified, representing 88.67% of the total constituents. The main compound was identified as Verticiol (18.16%), followed by Camphene (17.70%), γ-Gurjunene (7.15%), n-Butylcyclohexane (5.95%) and Bornyl acetate (5.86%). The oil was found to be rich in Monoterpene Hydrocarbons (32.05%), followed by Diterpenic alcohol (18.16%), Oxygenated hydrocarbons (13.27%), Sesquiterpene hydrocarbons (12.40%), Monoterpenic ester (5.86%), Cyclic ether (4.36%) and Oxygenated sesquiterpenes (2.57%). Antimicrobial activity of the essential oil of C. ladanifer was tested against two Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis) and two Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria, and three fungi (Candida albicans, Trichophyton rubrum and Aspergillus niger), by the microdilution method. In fact, strong inhibitory and bactericidal effect has been shown against all tested Gram-positive and Gram-negative bacteria. Indeed, strongest inhibitory and fungicide effect was exerted against the yeasts and molds studied. It seems following this study that the essential oil of C. Ladanifer has very significant antimicrobial activity, it shows a broad spectrum covering Gram-positive, Gram-negative bacteria, yeasts and fungi. KEYWORDS For centuries, medicinal plants have been used as a remedy for various diseases. Plants have the capability to synthesize a wide range of phytochemicals that possess significant biological functions. Many of these compounds have beneficial effects on human health and can be used to treat diseases (Mahesh and Satish, 2008; Prasannabalaji et al., 2012). Moreover, plants have the ability to synthesize aromatic substances, many of which are bioactive phytochemicals (Cowan, 1999). Over the past few years, the use of plant based natural antimicrobials in the treatment of bacterial infections has gained much recognition (Kasrati et al., 2014). Furthermore, antimicrobial resistance is now a global concern, which reached a crisis point in many hospitals worldwide. Indeed, there is an urgent need to replace our arsenal of anti-infective agents (Cushnie, 2011), by developing new antimicrobial agents. In this context, a great interest has been focused on the natural products,
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a NTF and its parameters, along with the evolution of connection weights and an architecture in Deep Neural Networks for Pattern Recognition problems. The evolutionary approach to an ANN training process consists of two major phases. The first phase is to decide on the representation of connection weights and an architecture: in a form of binary strings or not. In the experiments performed in this paper, the connection weights are represented as real-number matrices. The second phase is to develop an evolutionary process, in which search operators, such as crossover and mutation, have to be defined in conjunction with the representation scheme. In this paper we use crossover and mutation operators for evolving connection weights, transfer functions and an architecture of a deep neural network. In the scope of this paper we developed an evolutionary deep system to perform tests of the proposed method on different pattern recognition problems. The evolutionary cycle of the system is illustrated on Fig. 1, where: * Decode – decoding of each individual (genotype) in the current generation into a set of connection weights, transfer functions and an architecture, constructing a corresponding Deep ANNs. * Evaluate – evaluating effectiveness of each deep neural network by computing its total mean square error between actual and target outputs. The fitness of an individual is determined by the error. The higher the error, the lower the fitness. * Select – parents selection based on their fitness for the further reproduction. * Generate – applying search operators, such as crossover and mutation for the connection weights, an architecture and transfer functions to selected parents in order to generate offspring, which form the next generation. Fig. 1. An evolutionary cycle of the system. ## 3 Pattern Recognition Benchmarks In order to test the proposed system and make sure that it performs better on pattern recognition problems with different training and test datasets sizes, three benchmarks were employed. ### 3.1 Brodatz Textures The Brodatz Textures [18] are scans of a set of glossy black and white prints of the corresponding textures in the Brodatz book. While these prints are pictures of the same textures as in the book, in most cases they are not the same image as the one in the book. An example of the texture, which represents "Grass", can be seen on Fig. 2. Fig. 2. Example of the Brodatz Texture. Since this is a small dataset, it was decided to use only training data for the performance validation of the deep evolutionary system. The first 26 images from the dataset were used for the experiment. Original images were resized to 30 by 30 pixels. ### 3.2 Handwritten Digits For this benchmark problem MNIST [19] data set was used. It contains tens of thousands of scanned images of handwritten digits, together with their correct classifications. MNIST's name comes from the fact that it is a modified subset of two data sets collected by NIST, the United States' National Institute of Standards and Technology. Figure 3 shows a few images from the data set. The dataset was divided into two parts: the first part contains 1, 000 handwritten digits to be used as a training data and the second part contains 2, 000 images to be used as a test data. These images are 28 by 28 pixels in size. Fig. 3. Examples of images from MNIST. ### 3.3 COIL-100 The COIL-100 database [20] contains a set of 7, 200 colored images of 100 objects on a black background. Each object in the database is represented by 72 images. Figure 4 shows an example of the image from the original dataset. Fig. 4. A random image from COIL-100 database. Images were resized to 20 by 20 pixels and then grayscaled using the following formula for calculating luminance [21]: where: * – luminance of a pixel; * – are red, green and blue components of a pixel. For the training dataset it was chosen to use 40 images for each object and the other 32 images were used for the test dataset. In total 4, 000 images were used for the training dataset and 3, 200 for the test dataset. ## 4 Experimental Setting ### 4.1 Initial Architecture of the Deep Neural Network The architecture of an artificial neural network in the experiment is not constant and can change during the evolution process. However, we still have to define an initial architecture of the neural network. It was decided to initialize an architecture of the network with one hidden layer only and see if it evolves into a deep neural network. Table 1 describes a shape of the networks used at the initial stage for each benchmark. Table 1. Initial architectures of neural networks. Benchmark problem | ANN shape ---|--- Brodatz Textures | Handwritten digits | COIL-100 | It is important to notice that the evolved networks are truly deep: the number of hidden layers was varying between 4 and 5. For example, one of the evolutionary processes for COIL-100 benchmark produced a deep neural network with 4 hidden layers: . ### 4.2 Node Transfer Functions The list of transfer functions was used to evolve a DNN. Table 2 shows which functions were used. The default values of and for Unipolar Sigmoid, Sigmoid Prime, Hyperbolic and Bipolar functions are: , The default values of and for Gaussian function are: , . Table 2. List of node transfer functions. Function name | Equation ---|--- Step | Unipolar Sigmoid | Gaussian | Sigmoid Prime | Hyperbolic Sigmoid | Bipolar Sigmoid | ### 4.3 Representation of the Deep Evolutionary Neural Network We are going to use a NeuroEvolutionary approach to train a deep neural network in our system. Therefore, we have to decide how the network should be represented and which search operators should be used for the evolutionary process. A chromosome contains: 1. 1. An array of matrices with connection weights which are represented as real numbers. 2. 2. A matrix of NTFs for hidden layers and the output layer of the deep neural network. 3. 3. A matrix with parameters which are represented as objects for node transfer functions. Fig. 5. Graphical representation of a chromosome. Figure 5 shows a graphical representation of a chromosome in a DNN, where: n is a number of layers, , , ..., are matrices of connection weights between input-hidden, hidden-hidden and hidden-output nodes; , , ..., are arrays of transfer functions associated with each layer; , , ..., are arrays of parameters for each node transfer function. ### 4.4 Search Operators In the experiment we decided to use both crossover and mutation search operators to evolve a deep neural network. A population size in one generation is 100 chromosomes. The population is generated with a random number of hidden layers, random connection weights and transfer functions. We applied a randomized version of the crossover operator. The system takes two neighboring chromosomes and makes a copy of the first one, which forms a child chromosome. Then it iterates through all layers in the second chromosome and chooses at random a connection weight and a node transfer function to be copied into the child chromosome. The number of randomly chosen connection weights and transfer functions equals to , where n is the number of neurons in the layer of the current iteration. The mutation operator applies for both current chromosomes and for chromosomes generated as the result of the crossover procedure. A probability of the mutation in the connection weights and node transfer functions is . For connection weights, a mutation operator creates a random index for each layer and changes a connection weight value between and , where is the current value of connection weight and r is a randomly generated values between 0 and 1. For node transfer functions, a mutation operator also creates a random index for each layer and replaces a function located at that position with a random transfer function from the predefined list. For evolving parameters in node transfer functions, the mutation operator changes a value of between and 5.0. A value of changes between and 5.0 for Gaussian function and between 1.0 and 5.0 for Sigmoid, Sigmoid Prime, Hyperbolic and Bipolar functions. The generated population contains deep neural networks of different depth ranging from 1 to 5 hidden layers and it is not a subject to change during the evolutionary process. For an architecture, a mutation operator at first chooses a layer of the neural network, then it randomly chooses which operator to apply: add or remove. Add operator adds a new neuron to the previously chosen layer. Remove operators removes the last node from the layer. A probability of mutating an architecture of a deep neural network is . ## 5 Results For each benchmark problem 20 experiments were performed: 10 experiments for evolving a deep neural network with the sigmoid transfer function in each neuron and 10 experiments where node transfer functions were evolved for each neuron. Connection weights and architecture were simultaneously evolved during the NeuroEvolutionary process in all experiments. Each experiment contains 100 iterations. The result of each experiment is a number, which represents the root-mean-square error (RMSE) associated with running a network on the test data set. RMSE is defined by means of the following formula: (1) where: Table 3. Results for Brodatz Textures. N |
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there are other changes Win 8 makes that would take quite a lot of 3rd party software to replace. It's also possible to use 3rd party software on Win 7. Also, on many business/library/cafe/rental computers you aren't allowed to install third party software at all. Furthermore you're asking someone to spend money on 3rd party solutions, spend time installing and maintaining it, dealing with any security or stability issues, looking out for potential malware/adware included with these programs, etc. Or you can stick with Win 7 with its secure built in functionality. Finally there's the matter of principle. Do I really want to encourage MS's business tactic of reducing desktop functionality in order to familiarize users with MS's touch interface in an attempt to drive their failing phone and tablet sales? For me, the answer is definitely not, as it sets a dangerous precedent and encourages them to continue throwing desktop users under the bus. For those reasons it's better that we encourage MS to improve its products for desktop users rather than settling for third party software. At this point we can be sure the Start Menu is not coming back, so the best we can do is let them know what functionality they can add to the Start Screen to make it better for us. They can fix my WiFi -- at least once a day it stops working and I have to disable and re-enable it in device manager to get it working again (only takes about 10 secs - got it down to a fine art - but it is still a pain). Yes I know it is a a driver issue and therefore Intel's fault, but I never had any problems with it in 7. They can fix my WiFi -- at least once a day it stops working and I have to disable and re-enable it in device manager to get it working again (only takes about 10 secs - got it down to a fine art - but it is still a pain). Yes I know it is a a driver issue and therefore Intel's fault, but I never had any problems with it in 7. I have a similar problem with my W530 laptop using the Centrino Advanced-N 6205 card. The problem is much better using the WiFi drivers that get installed by Windows 8 however as I don't need to reset the WiFi now but it still takes a while to connect (some apps like IE, Lync and Steam seem to hang for around 30 secs.) after Win8 tells me it is connected to a WiFi network. The Intel drivers from their website were very bad i.e. disconnections requiring card reset and poor signal quality for VoIP I have a similar problem with my W530 laptop using the Centrino Advanced-N 6205 card. The problem is much better using the WiFi drivers that get installed by Windows 8 however as I don't need to reset the WiFi now but it still takes a while to connect (some apps like IE, Lync and Steam seem to hang for around 30 secs.) after Win8 tells me it is connected to a WiFi network. The Intel drivers from their website were very bad i.e. disconnections requiring card reset and poor signal quality for VoIP I have an "advanced" intel card too, maybe the same model, will check later. I'll have a go at uninstalling intel's drivers tonight and see what happens. More desktop themes available for those who want them like cherrywood, Faux glass, vista shiny plastic, metals, glass, with or without transparency and blue, and non skewmorphic ones like thinner borders no borders. Keyboard short cut customization turn things off like shift+up arrow (really annoying me when I type on Surface, they are right next to each other. More dynamic START themes option to download apps not in the store that are/aren't approved. Add a desktop section and windows phone section to the store Add Siri like voice command (should be more like Google Now really) Add Jumplist to right click on Start Screen Create an open standard for this like blasting music, screen cast, pictures, tv, movie to devices other than xbox over wifi, Bluetooth, or a new method For those who want it: disable start button (I never complained in the first place) Make IE 11 better add themes and extensions, smooth out the new tab transition and the rest of the UI. Let other browser be installed onto Windows 8/RT through the store Add vertical tile to the Start Screen, and longer ones that take up four medium tiles Add Modern UI Start Screen Task Manager Update all Icons Create File Explorer tab "Places" for libraries should have a unified location for all commands. Add Command bar (windows 7 style) to File Explorer Add terminal like to Windows FIX the TOOLTIP ISSUE when you rollover close windows (maximize restore minimize too) it STILL uses Windows 9x style tooltips The new task manager is ok, but botched a couple things. I don't agree with everything in this article, but it does highlight some of the issues. Probably best to go 3rd party with Process Explorer or Hacker. Win 8 seems to be even worse than Win 7 at how big of a hassle it is to regain user control of the OS and stop Windows from constantly phoning home. After installing the 8.1 preview i have been enjoying Windows 8.1 a lot more than 8.0. My new main annoyance is not something that didn't even bother me in 8.0. Desktop apps pinned to the start screen end up looking such a mess now the background is based on the icon colour: I much perefered it when all pinned desktop apps had the same background colour, i did really enjoy the look of the improved start screen until i actually installed and pinned apps i use...now its just a horrible mess of colours. Wish they would remover the glossy Windows 7 taskbar icon glow for a flatter one, and remove the damn taskbar transparency on the desktop. Would still like to see more desktop options moved to metro flyout panels on the desktop as well.A flat panel display device (FPD) such as an organic EL (Electro-Luminescence) display (OELD), a plasma display panel (PDP) or a liquid crystal display device (LCD) has such a structure that a glass substrate for an element having a display element such as a light-emitting element formed and a glass substrate for sealing are disposed to face each other and the light-emitting element is sealed in a glass package comprising two such glass substrates that are sealed together (Patent Document 1). Also for a solar cell such as a dye-sensitized solar cell, application of a glass package having a solar cell element (photoelectronic conversion element) sealed with two glass substrates have been studied (Patent Document 2). As a sealing material to seal a space between two glass substrates, application of sealing glass excellent in the moisture resistance, etc. is in progress. Since the sealing temperature of the sealing glass is at a level of from 400 to 600° C., properties of an electronic element portion of the OEL element or the dye-sensitized solar cell will be deteriorated when firing is conducted by using a conventional heating furnace. Accordingly, it has been attempted that a sealing material layer (a layer of a glass material for sealing) containing a laser absorbent is disposed between sealing regions provided on the peripheral portions of two glass substrates, and the layer is irradiated with a laser light to heat and melt the layer thereby to form a sealing layer (Patent Documents 1 and 2). Sealing by laser irradiation (laser sealing) can suppress thermal influences over the electronic element portion, and on the contrary, it has a disadvantage that cracks, fractures and the like are likely to form on the glass substrate. One reason of the problem may be the difference in the thermal expansion coefficient between the glass substrate and the sealing glass. With respect to this point, Patent Document 2 describes a sealing material having a thermal expansion coefficient within 10×10−7/° C. from that of the glass substrate. Since the thermal expansion coefficient of a sealing glass is larger than that of a glass substrate in general, besides a laser absorbent, a low-expansion filler such as silica, alumina, zirconia or cordierite is added to the sealing glass to obtain a sealing material having a low expansion coefficient. By the way, reduction of the thickness of a glass package constituting e.g. a FPD or a solar cell tends to be in progress, and for this purpose, it is required to narrow the gap between the glass substrates to be, for example, at most 15 μm. Since e.g. the low-expansion filler is added to the sealing material as described above, it becomes necessary to reduce the particle size of the filler particles along with narrowing of the substrate distance. Reduction of the particle size of the filler particles causes increase of the specific surface area, and a sharing stress between the sealing glass melted by heat of the laser light and the filler particles increases to reduce fluidity. Accordingly, it becomes necessary to increase the process temperature (heating temperature) by the laser light, but when the process temperature is increased, a problem such that a crack or breakage etc. tends to occur in the glass substrates or the sealing layer.This product uses the FRED® API but is not endorsed or certified by the Federal Reserve Bank of St. Louis. 4Bedrooms 2Bathroom 0.42Acreage 2164Square Feet 4 bed - 2 bath Beautiful home nestled in 1/2 acre of wooded area. All hardwood floors which have been
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Day is dependent on the generosity of its partners, volunteers and supporters for survival. If you would like to sponsor Ada Lovelace Day, please get in touch. We would like to thank the following organisations for their support of Ada Lovelace Day and women in STEM.Phrenic Nerve Conduction Abnormalities Correlate with Diaphragmatic Descent in Chronic Obstructive Pulmonary Disease. Diaphragmatic weakness in chronic obstructive pulmonary disease (COPD) is ascribed to hyperinflation-induced diaphragm shortening as well as impairment in cellular and subcellular structures. Although phrenic neuropathy is known to cause diaphragmatic weakness, phrenic neuropathy is rarely considered in COPD. This work aimed at assessing phrenic nerve conduction in COPD and its relation to radiographic hyperinflation and pulmonary function. Forty COPD patients were evaluated. Radiographic parameters of lung hyperinflation were measured on postero-anterior and lateral chest x-ray films. Flow volume loop parameters were obtained from all patients. Motor conduction study of the phrenic nerves was performed and potentials were recorded over the xiphoid process and the ipsilateral 7th intercostal space. Twenty-seven healthy subjects were enrolled as controls. Parameters of phrenic nerve conduction differed significantly in patients compared to controls. Phrenic nerve abnormalities were detected in 17 patients (42.5%). Electrophysiological measures correlated with diaphragmatic angle of depression on lateral view films and with lung height on postero-anterior films. They did not correlate with the flow volume loop data or disease severity score. Phrenic nerve conduction abnormality is an appreciated finding in COPD. Nerve stretching associated with diaphragmatic descent can be a suggested mechanism for nerve lesion. The presence of phrenic neuropathy may be an additional contributing factor to diaphragmatic dysfunction in COPD patients.Sulfone treatment of granuloma annulare. Although spontaneous remission of granuloma annulare is not uncommon, most cases are chronic and resistant to a variety of therapeutic modalities. In our study we confirm the beneficial effect of dapsone treatment in patients with localized or generalized granuloma annulare. The results indicate that dapsone is a useful drug to control or at least to improve skin lesions in the majority of patients.Direct gem-difluoromethylenation of sp(3)-hybridized carbon center through copper-mediated radical/radical cross-coupling for the construction of a CH2-CF2 linkage. Efficient direct gem-difluoromethylenation of an sp(3)-hybridized carbon center in benzyl bromides using benzo-1,3-azolic (oxa-, thia- or aza-) difluoromethyl bromides for construction of a CH2-CF2 linkage has been developed through radical/radical C-C cross-coupling via two separate single electron transfer processes (SET) under the promotion of different copper sources.The Court-Martial of Jackie Robinson The Court-Martial of Jackie Robinson is a 1990 American drama film directed by Larry Peerce and written by L. Travis Clark, Steve Duncan, Clay Frohman and Dennis Lynton Clark. The film stars Andre Braugher, Daniel Stern, Ruby Dee, Stan Shaw, Paul Dooley and Bruce Dern. The film premiered on TNT on October 15, 1990. Plot Cast Andre Braugher as Jackie Robinson Daniel Stern as William Cline Ruby Dee as Jackie's mother Stan Shaw as Joe Louis Paul Dooley Bruce Dern as Scout Ed Higgins Kasi Lemmons as Rachel J. A. Preston as Wendell Smith Michael Greene Dale Dye Steven Williams as Satchel Paige Noble Willingham Gary Grubbs Don Hood as Maj. Foley Howard French as Sgt. McEllroy Jim Beaver as Maj. Trimble Russell Curry as Mack at 21 Peter Parros as Gordon Jones Nancy Cheryll Davis as Loretta Jones Dale Swann as Dr. Smith Glenn Morshower as Capt. Spencer Brenda Ballard as Miss Wharton Ken Kerman as Asch Chris Kinkade as Cpl. Dwight References External links Category:1990 television films Category:1990s drama films Category:American films Category:American drama films Category:English-language films Category:Cultural depictions of Jackie Robinson Category:American films based on actual events Category:Films directed by Larry Peerce Category:Military courtroom films Category:TNT Network original films<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Strict//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd"> <html xmlns="http://www.w3.org/1999/xhtml" lang="sk" xml:lang="sk"> <head> <!-- * * Copyright 2008-2009, Haiku. All rights reserved. * Distributed under the terms of the MIT License. * * Authors: * Humdinger <[email protected]> * Translators: * Marek * --> <meta http-equiv="content-type" content="text/html; charset=utf-8" /> <meta http-equiv="Content-Style-Type" content="text/css" /> <meta name="robots" content="all" /> <title>Pracovné plochy</title> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <link rel="stylesheet" type="text/css" href="../Haiku-doc.css" /> </head> <body> <div id="banner"> <div><span>Používateľská príručka</span></div> </div> <div class="nav"> <div class="inner"> <ul class="lang-menu"> <li class="now">Slovenčina&nbsp;<span class="dropdown-caret">&#9660;</span></li> <li><a href="../id/workspaces.html">Bahasa Indonesia</a></li> <li><a href="../ca/workspaces.html">Català</a></li> <li><a href="../de/workspaces.html">Deutsch</a></li> <li><a href="../en/workspaces.html">English</a></li> <li><a href="../es/workspaces.html">Español</a></li> <li><a href="../fr/workspaces.html">Français</a></li> <li><a href="../fur/workspaces.html">Furlan</a></li> <li><a href="../it/workspaces.html">Italiano</a></li> <li><a href="../hu/workspaces.html">Magyar</a></li> <li><a href="../pl/workspaces.html">Polski</a></li> <li><a href="../pt_PT/workspaces.html">Português</a></li> <li><a href="../pt_BR/workspaces.html">Português (Brazil)</a></li> <li><a href="../ro/workspaces.html">Română</a></li> <li><a href="../fi/workspaces.html">Suomi</a></li> <li><a href="../sv_SE/workspaces.html">Svenska</a></li> <li><a href="../tr/workspaces.html">Türkçe</a></li> <li><a href="../zh_CN/workspaces.html"> 中文 ［中文］</a></li> <li><a href="../ru/workspaces.html">Русский</a></li> <li><a href="../uk/workspaces.html">Українська</a></li> <li><a href="../jp/workspaces.html">日本語</a></li> </ul> <span> « <a href="gui.html">Používateľské rozhranie Haiku</a> :: <a href="contents.html" class="uplink">Obsah</a> :: <a href="twitcher.html">Twitcher</a> » </span></div> </div> <div id="content"> <div> <h1>Pracovné plochy</h1> <p>Pracovné plochy sú virtuálne plochy, so samostatným rozlíšením, sýtosťou farieb a pozadím. Až 32 týchto pracovných plôch môže byť nastavených z nastavení <a href="preferences/screen.html">Obrazovky</a>.</p> <img src="../images/workspaces-images/workspace_overviewpng.png"
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was conducted. The findings showed that the frequency of interacting with difficult patients positively related to surface acting. Perceived organizational support (POS) positively related to deep acting and negatively to surface acting. The results also showed that surface acting related negatively, and deep acting related positively, to job satisfaction. The frequency of interactions with difficult patients related positively to emotional exhaustion, and negatively to job satisfaction. Perceived organizational support related negatively to emotional exhaustion and positively to job satisfaction. The results suggest that job demands, resources and emotional labour can predict nurses' well-being. The results of the present study indicate that nurses' well-being can be predicted by job demands, resources and emotional labour. There is a need to address organizational support and training programmes to enhance job satisfaction and reduce emotional exhaustion among nurses.[Study on the causes and risk factors on vertigo and balance disorders in 118 elderly patients]. To understand the various factors causing vertigo and balance disorders in the elderly. 118 elderly patients (aged equal or older than 60 years of age) with vertigo or balance disorders were retrospectively analyzed through clinical symptoms, audio-vestibular function tests, X-ray, CT scan or MRI in cervical vertebras, brain and inner ears, ultrasonography, transcranial doppler (TCD) or magnetic resonance angiography (MRA) in blood vessels on head and neck. Of 118 patients, 70 (23%) of them suffered perip heral vestibular disorders while 29 (58%) having cerebral vertigo or dizzness, leaving 19 cases (16%) as unclassified. For elderly patients, vertigo and balance disorders were commonly caused by many kinds of peripheral and cerebral vestibular pathological disfunctions while the functional weakness of vestibular organs and systems affected by the physiological process of ageing and different concommitant diseases as well as environmental, psychogenic factors should also be considered.Structural robustness Robustness is the ability of a structure to withstand events like fire, explosions, impact or the consequences of human error, without being damaged to an extent disproportionate to the original cause - as defined in EN 1991-1-7 of the Accidental Actions Eurocode. A structure designed and constructed to be robust should not suffer from disproportionate collapse (progressive collapse) under accidental loading. Buildings of some kinds, especially large-panel systems and precast concrete buildings, are disproportionately more susceptible to collapse; others, such as in situ cast concrete structures, are disproportionately less susceptible. The method employed in making a structure robust will typically depend on and be tailored to the kind of structure it is, as in steel framed building structural robustness is typically achieved through appropriately designing the system of connections between the frame's constituents. Design considerations Three alternative measures are used, sometimes jointly, to achieve structural robustness and reduce the risk of disproportionate collapse. These are: Reducing the possibility of occurrence of accidental loading. Preventing the propagation of a possible initial failure and increasing redundancy. Which includes the indirect method and the alternative load path method. Designing the structure to withstand accidental loading. Sometimes referred to as specific load resistance method. Robustness requirements in Eurocodes The requirements for structures in consequence classes 2 and 3 can be found in EN 1991-1-7 Eurocode 1 - Actions on structures - Part 1-7: General actions - Accidental actions. Additional requirements and requirements for structures in consequence class 1 can be found in the material specific Eurocode parts, EN 1992 for concrete structures, EN 1993 for steel structures and so on. In EN 1991-1-7 buildings are categorised in consequences classes, considering the building type, occupancy and size. Consequence class 1, low consequences of failure: Single occupancy houses not exceeding 4 storeys. Agricultural buildings. Buildings into which people rarely go, provided no part of the building is closer to another building, or area where people do go, than a distance of 1.5 times the building height. Consequence class 2a, lower risk group - medium consequences of failure: 5 storey single occupancy houses. Hotels not exceeding 4 storeys. Flats, apartments and other residential buildings not exceeding 4 storeys. Offices not exceeding 4 storeys. Industrial buildings not exceeding 3 storeys. Retail premises not exceeding 3 storeys of less than 1000 m² floor area in each storey. Single storey educational buildings. All buildings not exceeding two storeys to which the public are admitted and which contain floor areas not exceeding 2000 m² at each storey. Consequence class 2b, upper risk group - medium consequences of failure: Hotels, flats, apartments and other residential buildings greater than 4 storeys but not exceeding 15 storeys. Educational buildings greater than single storey but not exceeding 15 storeys. Retail premises greater than 3 storeys but not exceeding 15 storeys. Hospitals not exceeding 3 storeys. Offices greater than 4 storeys but not exceeding 15 storeys. All buildings to which the public are admitted and which contain floor areas exceeding 2000 m² but not exceeding 5000 m² at each storey. Car parking not exceeding 6 storeys. Consequence class 3, high consequences of failure: All buildings defined above as Class 2 Lower and Upper Consequences Class that exceed the limits on area and number of storeys. All buildings to which members of the public are admitted in significant numbers. Stadia accommodating more than 5000 spectators. Buildings containing hazardous substances and / or processes. For buildings intended for more than one type of use, the consequences class should be that of the most onerous type. Buildings in consequence class 1 should be designed and constructed in accordance with EN 1990 - 1999 for satisfying stability in normal use, no specific consideration (required by EN 1991-1-7) is necessary with regard to accidental actions from unidentified causes. Buildings in consequence class 2a (in addition to what is recommended for consequence class 1) should be provided with effective horizontal ties, or effective anchorage of suspended floors to walls. Buildings in consequence class 2b (in addition to what is recommended for consequence class 1 and 2a) should be provided with effective vertical ties in all supporting columns and walls, or alternatively the building should be checked to ensure that upon the notional removal of each supporting column and each beam supporting a column, or any nominal section of load-bearing wall (one at a time in each storey of the building) the building remains stable and the local damage does not exceed a certain limit. Where the removal of such columns and sections of walls would result in an extent of damage in excess of the agreed limit, such elements should be designed as a key element. For buildings in consequence class 3 a systematic risk assessment of the building taking into account both foreseeable and unforeseeable hazards, is required. See also Extreme Loading for Structures List of structural failures and collapses Ronan Point Structural failure References External links EN 1991-1-7 Eurocode 1 - Actions on structures - Part 1-7: General actions - Accidental actions SCI P391 Structural Robustness of Steel Framed Buildings Practical guide to structural robustness and disproportionate collapse in buildings Design of precast concrete structures with regard to accidental loading Ir. Arnold Van Acker How to design concrete buildings to satisfy disproportionate collapse requirements O Brooker BEng, CEng, MICE, MIStructE Portland Cement Association Structural Integrity Requirements for Concrete Buildings Review of international research on structural robustness and disproportionate collapse Structural-Safety Incorporating CROSS and SCOSS Category:Structural engineering Category:Safety engineering Category:Structural steel Category:Concrete Category:Infrastructure Category:Civil engineeringEstablishment of an integration-free induced pluripotent stem cell line (MUSIi005-A) from exfoliated renal epithelial cells. Human induced pluripotent stem cells (iPSCs) were generated from exfoliated renal epithelial cells isolated from a urine sample of a 31-year-old healthy woman. Epithelial cells were characterized for the expression of E-cadherin and reprogrammed using non-integrating Sendai viral vectors. The urine-derived iPSC line (designated as MUSIi005-A) was karyotypically normal, expressed pluripotent markers, differentiated into cells of three embryonic germ layers, and showed no viral and transgene expressions at passage 29. Our protocol offers a non-invasive and efficient approach for iPSC generation from patients with genetic or acquired disorders.<?php /** * List View Class for PDF Settings. * * @copyright YetiForce Sp. z o.o * @license YetiForce Public License 3.0 (licenses/LicenseEN.txt or yetiforce.com) * @author Maciej Stencel <[email protected]> * @author Mariusz Krzaczkowski <[email protected]> */ class Settings_PDF_List_View extends Settings_Vtiger_List_View { public function preProcess(App\Request $request, $display = true) { $viewer = $this->getViewer($request); $viewer->assign('SUPPORTED_MODULE_MODELS', Settings_PDF_Module_Model::getSupportedModules()); parent::preProcess($request, $display); } } Thomas Gottschalk Thomas Gottschalk Mobisol Chief Executive Officer Thomas Gottschalk is Founder and Chief Executive Officer of Mobisol,
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few. This learning experience has further equipped us with the tools necessary to promote future projects, especially those which may be of an unpopular nature.\" AFA President Donald E. Wildmon has written an interesting little Rant. This is the most Anti-ALA rant I have ever seen, might be the most Anti-Anything rant I have ever seen. It\'s kind of like being transported to the 50\'s and listening to Joseph McCarthy speak (I can only imagine). Can I say that and still not take any sides on this one? \"It is critically important for our children and our communities that we free our local libraries from the grip of the American Library Association and make our libraries safe for our children! Make no mistake, the danger to our children is real!\" MSN Entertainment was one of the places with this Story. The Dr. Laura TV show has been canned in Canada due to low ratings. \"\"Our audience has voted and, unfortunately, they\'ve cast a \'nay\' ballot for Dr. Laura on television,\" says Roy Gardner, a vice president of programming for CanWest Global Communications. \"The latter part of the afternoon is very important to us because it forms the lead-up to our evening news programming, and Dr. Laura just isn\'t delivering the viewers.\" \" \"This article contemplates factors affecting the usabilty of web sites. It addresses issues from both the disciplines of psychology and computing and attempts to consider the relevance of these issues with regards to a study carried out at the Centre for Information Environments Research at Brunel University. The study was developed in order to investigate issues affecting the usability of web sites. A test site was created and investigations revealed some interesting findings, some of which are detailed in the article. Bibliofuture has a great Article by Ana Arias Terry on E-Books. It covers the basics of E-Books, who makes them, how they work, and what the future holds. \"If e-book content sellers such as alternative presses and device vendors intend to stay in the e-book game, they will want to pay special attention to the demands of the market and heed their preferences. Otherwise, they run the risk of finding themselves in the print pages of historical discussions.\". OpenMind Publishing Group is taking its first step to replace traditional textbook publishing with a personalized, online process. OpenMind today announced the first-ever program that carries the open source model into the textbook publishing industry. For more information on OpenMind Publishing Group and/or to see a demonstration please visit www.ompg.com or 919-688-4555. IDC has a research Report on the future on Knowledge Management. They say the software market in this segment will grow the worldwide market from $1.4 billion in 1999 to $5.4 billion in 2004.They also have a nice definition of knowledge management. \"The importance of examining organizational processes and technologies and developing solutions that harvest and deliver the right information to the right people at the right time\" \"The need to more intelligently support the decisions of employees while improving productivity will create and sustain demand for knowledge management access software,\" said Brian McDonough, senior research analyst with IDC\'s Knowledge Management program. \"The infrastructure is largely in place. Consolidation among vendors through acquisitions or strategic partnerships will occur to further spur rapid market adoption.\" This Story, from Wired, gives an update on the Commission on Child Online Protection [COPA]unanimously endorsed a largely hands-off approach to the Internet, while saying that practices such as mislabeling adult sites as innocuous should be against the law. The final report does not recommend additional criminal laws or a .xxx or .sex top-level domain. Instead, it calls for more \"public education\" and \"responsible adult empowerment.\" Be sure to check out the COPA Research Papers , a collection of Pro and Con reports from a wide spectrum of folks on both sides of the debate, including: European Union, Gay & Lesbian Alliance Against Defamation, Morality in Media, OCLC Office of Research, Peacefire.org, and U.S. National Commission on Libraries and Science. Bob Cox sent in This Story from Alabama Live that is good news for all those considering an addition to the library. The Birmingham, Alabama Public Library added a bookstore last December to replace the spring and fall book sales the library once had. In a report to the Sept. 28 board meeting, Library Director Jack Bulow said the Bookstore brought in $13,000 in its first nine months of operation. Not bad! E&P Online has a Story that talks about News librarians. They say news librarians are much better appreciated these days, and their roles are expanding. The skills the librarians possess are becoming increasingly important. Journalists run the risk of smothering in the information overload, librarians/news researchers help make sense of it all. Now why can\'t other librarians get this kind of respect? A new book is out that should be of some use to journalists who want to be better skilled at using the Internet as an integral part of their reporting. \"Super Searchers In The News\" (Information Today Inc.), written by Paula Hane and edited by Reva Basch, takes the approach of interviewing 10 experts in using the Internet as a news research tool. The DMCA continues to send shivers down my spine. Wired has a Story that has some not-so-nice things to say. Critics of the DMCA say it could lead to a pay-per-use world where consumers don\'t truly own the books, movies and music they purchase. On Oct. 28, the librarian of Congress will announce new rules governing the access provisions of the DMCA. Remember: Fair use is not a defense to the DMCA. \"The technological measures, which may be as simple as a password, place restrictions on who can use the digital information and often disenfranchise the public. Whereas the public may use the same print resources in a law library, in the digital arena law libraries are no longer able to provide equal access to all users.\" Internet World has a nice Story that likens the internet to a library where books are strewn across the floor rather than arranged in neatly organized stacks. They say libraries have \"metadata\": specific descriptive elements like \"subject\" and \"author\" that are recorded and indexed in a standardized way, unlike the net, which is a big mess. Maybe The Dublin Core Metadata Initiative will finally take off.? \"What we see is that the necessary expertise to develop metadata applications is declining,\" says Stuart Weibel, co-director of the Dublin Core Metadata Initiative. Ever vigilant Bob Cox sent in this Story from Boston.com on some very rare books that went missing from Harvard. In March, Chun Shum, a rare books specialist at the library, discovered treasured volumes of poetry and painting date back more than 1,000 years, had been snatched from their protected perch in the rare book room. \'\'These are works of huge historic and literary importance,\'\' said Nancy Cline, head librarian of Harvard College, who oversees the world\'s largest academic collection of books. \'\'It\'s very difficult to estimate the impact of their loss.\'\' Governor George W. Bush, during a presidential campaign stop Sunday in Holland, told a local Christian radio station he believes filters that block \'pornography and smut\' should be installed on all Internet services available in public places such as libraries. As seen on The Maranatha Christian News Service. \"Gary Glenn, president of the American Family Association of Michigan said \"On behalf of millions of concerned Michigan parents, we are deeply grateful to Governor Bush for his unequivocal stand in support of Internet pornography filters in libraries and other public places\" From The Times UK a shocking Story on the first Harry Play. A 17 Year old girl will play Harry after J. K. Rowling gave permission for a boarding school to stage the world premiere of Harry Potter and the Philosopher\'s Stone. North Foreland Lodge, a girls-only school near Hook in Hampshire, wrote to the author after two staff decided to adapt her first novel for its Christmas production. She gave her approval, despite a seven-year block on performing rights because of the impending Hollywood film. The Houston Chronicle has a Story on a TX town that is trying to figure out how to keep books that include vulgar words out of classrooms. The district\'s school libraries already require parental permission for children to check out books from author J.K. Rowling\'s you know what series. They say they put the policy in place to give parents who don\'t want their children reading such material a way to prevent it. \"\"In today\'s public schools, there seem to be a lot of books creeping in that have four-letter profanity in them,\" board member John Couch said. \"We happened to discover some in the fifth and sixth grades, and we\'re concerned that that kind of language is getting past some of the teachers and into the hands of students. Daniel Chudnov has the Docster list up and running now.This list is intended for those wishing to help build and test a doc
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this; } Muzaffarabad:India and Pakistan have suspended trade across their de facto border in the disputed territory of Kashmir after Indian authorities detained a truck driver accused of drug trafficking. Kashmir has been divided between India and Pakistan since the two countries won independence from Britain in 1947. Both claim the scenic Himalayan territory in full. Patrolling the Line of Control in Kashmir, where trade has been halted. Credit:AFP Barter trade across the de facto border began in 2008 as part of peace efforts, but it is frequently disrupted by disputes. "We were informed by the Indian authorities on Friday evening that they have stopped 22 Pakistani trucks which crossed the Line of Control earlier that day," said Basharat Iqbal, trade facilitation officer on the Pakistani side of the border. "They told us that they had discovered 12 kilograms of opium from a truck carrying oranges and were taking an action against the driver. After the incident, we also held 50 Indian trucks on Pakistani Kashmir side, because traffic crosses the border simultaneously," Mr Iqbal said. Imtiaz Wayen, director-general of Pakistani Kashmir's trade and travel authority, said India was not entitled to stop Pakistani drivers on the grounds of smuggling. "According to our agreement, if they find any banned item in our trucks they are bound to hand over that item and the relevant truck driver to us for further action," he said. "We have informed the officials of the ministry of foreign affairs about this matter and have asked them to take up this issue." AFPThe terms “sub-surface formation” and “downhole formation” typically refer to the rock formation around a bore which has been drilled into the ground. The borehole provides a path for hydrocarbons, such as oil and gas, in the rock formation to be brought to the surface. Sub-surface formations from which hydrocarbons are produced, typically contain a fluid which includes liquid and gas mixed together. The liquid from the downhole formation will normally require pumping to bring it from the downhole formation to the surface. Pumps used for pumping the fluid from the downhole formation to the surface, such as progressing cavity pumps, piston pumps or electric submersible pumps, operate more efficiently if there is no gas in the fluid being pumped. Also, the presence of gas in the fluid being pumped can damage the pump, through heat generation, cavitation or gas absorption. There are various devices known for separating gas from liquid in a downhole application. See, for example, U.S. Pat. No. 5,902,378 to Obrejanu, incorporated herein by reference in its entirety. Typically, the more gas which can be eliminated from the fluid, the better the operation of the pump.Bag of popcorn already had the dollar bill in it. Kid gets a bill from Howie and makes a switch with a fake (albeit a very good one) bill that has the same serial # as the real one in the popcorn bag. Howard reads serial #. Kid switches fake bill with flash paper bill while folding it. Hocus-pocus, open the bag, serial # matches. Return that bill to Howie, or switches that bill with the one originally received from Howie and gives that one back. Did it rather well, however it was done. And couldn't that first guy have dressed a little better for this??? No need to go to a tux or anything, but dude, really bad jeans and a stupid 'check out receipt' T-shirt??? Didn't like that aspect at all. Bag of popcorn already had the dollar bill in it. Kid gets a bill from Howie and makes a switch with a fake (albeit a very good one) bill that has the same serial # as the real one in the popcorn bag. Howard reads serial #. Kid switches fake bill with flash paper bill while folding it. Hocus-pocus, open the bag, serial # matches. Return that bill to Howie, or switches that bill with the one originally received from Howie and gives that one back. Did it rather well, however it was done. Spoiler for a question: Spoiler: So do you think that Nick was in on it (Nick: "He's taking my snacks"), or that the magician happened to be using the same brand/size snacks that they were providing to Nick? Seems a bit suspect to me. Very good trick either way, though. So do you think that Nick was in on it (Nick: "He's taking my snacks"), or that the magician happened to be using the same brand/size snacks that they were providing to Nick? Seems a bit suspect to me. Very good trick either way, though. Spoiler: I don't think those were actually Nick's snacks at all, just another one of those silly things Nick says in his 'duties' as ringmaster. I didn't take a close look at the bag, but I didn't immediately recognize it as something I knew. I just figured it could be either (a) a regional brand of something that I wouldn't know about in the Midwest or (b) a generic 'popcorn' snack bag or something like that - along the lines of a pop can that says "Cola" on it. The guy's own prop that he brought with him, not something he just found there and chose to utilize. i just watched this trick and he took the bill and immediately held it up to the camera and the serial number matched what was read. There wasn't any cut away, so I don't see how he could have swapped the bill. I'm not saying he couldn't have, but even in slow mo it didn't show (or they cut part of the act). I don't watch this show, but I saw something on the young man singing opera, this morning, so I found the video and watched him. Love him! These are the stories that I love and, of course, his talent is brilliant. I cried. I don't know what the song was about but it sounded so tragic. I hope he has every success after having to deal with the awfulness of his 'family' in tossing him out for being gay. I loved how Howie said they were his family now and they are very proud of him. Con te Partiro (loosely translated in the English version as "Time to say Goodbye" but a literal translation of the title is "I will go with you".) Andrea Boccelli and Sarah Brightman have both recorded it. Agreed, and that's my biggest complaint about the show. I don't need 5 minutes of backstory on contestants in the first round (which Idol is also famous for). They should be showing parts of 30 acts per hour. Just show the acts. Frustrating. I agree, and it would kill me to have to watch this without a DVR and/or to watch it without doing something else, like playing with an ipad during the backstories. The content-to-noise ratio of the auditions in poor and getting poorer. I thought in the beginning of the series we were able to see many more acts than we do now. I also noticed last week a lack of "bad" acts. It's taking some of the suspense out of it, I no longer wonder if each act is going to be good or bad, but generally assume it's going to be good. The exception is a rapid-fire assortment of 4 bad acts, usually timed for the middle of the episode. It's becoming too predictable. Quote: Originally Posted by pmeyers I hear ya! I also find it uncomfortable to watch 10 year olds doing dances like the samba and other "sexy" latin dances. I just don't like it. I dislike almost all of the acts with kids. They're almost universally a kid doing something well that you would expect the kid to not be able to do. It's not the "best talent" in America; it's average talent from an unexpected source. I feel the same way about people-who-don't-look-like-opera-singers-singing-opera, now a recurring theme on the show. They aren't really good opera singers. They're just average singers with an unconventional physical appearance for the genre. __________________ 1 Roamio Plus 2 Lifetime Premieres, 2 HDs, 2 S2DTs 1 Original Philips S1 from all the way back in 1999!Q: Prolog : Operator Expected I get the "Operator Expected" error at the end of the two following rules but i can't understand why. testDrivenChecking :- %Stores all the methods of the projet which are tested by a unit test findall(allTestedMethods, (create(allTestMethods, 'method', _, _), addProperty(allTestMethods, 'annotation', 'Test', _, _), %Method created and ensures that it's a test. not(delete(allTestMethods, 'method', _, _)), %The test should not be deleted addReference(allTestMethods, 'calls', allTestedMethods, _, _), not(remReference(allTestMethods, 'calls', allTestedMethods, _, _))), %Ensures that the test keep testing the method allTestedMethodsList), list_to_set(allTestedMethodsList, allTestedMethodSet), %Stores all
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346, 38478, 12, 39, 22 ]
, some keys will have the same functions as they do when you're in the runtime. Double-click on the circle above "listvalues" on the "runform" part of the tree. The information there tells you that when you are looking at a list- of-values in Oracle Forms Runtime, some additional keys are available for additional functions. These keys are available only when you're in a list- of-values; when you leave the list, they do not have those functions any more. If you want to change the key bindings at any level, click on a circle and press "Edit Key Bindings". If you are looking at a list-of-values in Runform and you press a key, then Oracle Forms will look for that key's binding at the "listvalues" level of its resource file; and if it can't find the binding there it will search up through the tree for the binding until it reaches the top. If it cannot find it there then Forms will give you an "invalid function key" error. Here is an example showing how to add a key mapping to Oracle Forms, so the F3 function key on your keyboard will do an EXIT (just like Control-Q already does): 1) If you have the Forms Designer, Generator, or Runtime running right now, then quit out of them, or else Oracle Terminal will not be able to open the Forms resource file. 2) We will be editing the FMRPC.RES file, so make a backup copy of it before we begin. (You could just edit that file and save your changes as a new .RES file, except that there is a bug in Forms 4.0.12 that prevents it from using any terminal file other than FMRPC.RES.) This file is in ORAWINFORMS40. 3) Start up Oracle Terminal by double-clicking on its icon, or running "OT.EXE" from the "File Run" menu selection. When it asks you to open a file, navigate to ORAWINFORMS40 and choose "FMRPC.RES". 4) Open the key binding editor by either clicking on the "K key" icon, picking the "Functions Edit keys" menu selection, or pressing Control-M. 5) Double-click on the circle above "windows-sqlforms (at the left edge of the window), or click once on it and press "Edit Key Bindings". This brings up a window showing you the keys that are universally mapped across all of the Oracle Forms tools (since you are showing the key mappings list for the highest level of the hierarchy). 6) Click on the "Insert Row" button. This adds another line for you to put a new key binding on. 7) Enter the word "Exit" on your new row in the Action column (you must type it with a capital "E" and lower-case "xit"), and enter "F3" in the "Binding" column. 8) Click "OK" to return to the key binding editor. 9) Make sure that the F3 key is not mapped to something else lower in the hierarchy, by double-clicking on each of the circles to the right of "windows-sqlforms" and making sure that F3 is not shown in the list of key bindings. If you do find it in the key bindings for another level, then delete it with the "Delete Row" button. 10) Click "OK" to dismiss the key binding editor when you are finished with it. Now that you've added a new key binding, you need to generate and save it before you can use it: 1) Click on the "generate" button (the meat grinder, the rightmost icon), pick the "Functions Generate" menu selection, or press Control-G. If it asks you if you want to save your changes before you generate, then choose "yes". After it generates, it should display a dialog box telling you that the generate completed successfully. 2) Save your changes by picking the "File Save" menu selection, and exit Oracle Terminal by picking "File Exit". Note: Both of the save actions mentioned above (before the generate and after the generate) are necessary; the first action saves the structire changes which are necessary to perform the generate successfully, and the second save saves the fully generated, complete file. Now try starting up Forms Runtime, and pressing F3 to see if it successfully exits the application. F3 should also appear when you tell Forms to "Show Keys". You can map many keystrokes all to the same action, but you cannot map one specific keystroke to more than one action. PRODUCT ACTIONS You can only bind a keypress to an action that's available at a given level of Oracle Forms. Sometimes you will want to define a key for an action that does not already exist at that level, so you will have to add the action. A list at the end of this bulletin shows many of the actions that Oracle Forms recognizes and can respond to. You can add these actions to any level of the Oracle Forms tools and bind keys to them to make them useable. Here is an example of how to define the "User Defined Key 2" action in Oracle Forms Runtime, and bind it to the F2 key: 1) Close any Oracle Forms tools (Designer, Generate, Runtime) that you might have running, so you can modify their resource file without getting any "file already open" errors. 2) You will be editing ORAWINFORMS40FMRPC.RES, so make a backup copy of it for safekeeping. 3) Run Oracle Terminal, and open FMRPC.RES. 4) Go into the key binding editor, and click on the "Product Actions" button. This brings up the Product Actions Editor, which looks like the Key Bindings Editor. 5) Double-click on the circle above the word "runform". This brings you to the Product Action definition screen. 6) Insert a new row by clicking on the "Insert Row" button. 7) Put the phrase "User Defined Key 2" in the Action column, and put 84 in the Code column. 8) Click "OK" to dismiss the Product Action dialog, then click "OK" in the Product Action Editor to dismiss it too. Now you have made that action available for the level you are editing. All that remains is to bind a key to it, to make it useful. Here's a summary of the instructions given above for how to add a key binding: 1) In the Key Binding Editor, double-click on the "runform" circle. 2) Press the "Insert Row" button, and define a new binding with action "User Defined Key 2" and binding "F2". Click "OK" to close the Key Binding Definition window. 3) Make sure that the "F2" key is not bound at any other level below "runform" by checking the Key Binding Definition entries for all circles connected to "runform" to the right of it. 4) Press the "OK" button to dismiss the Key Binding Editor, and generate the new key bindings by clicking on the Generate icon in the FMRPC.RES window. Save your new bindings by selecting "Save" from the File menu. 5) Exit Oracle Terminal, and test this new action by putting a KEY-F2 trigger in a form and using Runform to make sure that it works. Oracle Terminal is a oracle tool which cannot be install during typical installation for oracle developer.If you not have install it by oracle developer cd.This tool help to map the functions key.For example on run time you want to exit when press ESCAPE key this work is possible through oracle terminal.We could restrict keys also same as Visual basic KEYPRESS trigger.Follow the steps of Himanshu if any problem told me I send you brief information. Thank you very much bcz your Key Mapping information is to clear ...but i am facing the problem that i am unable to find the "FMRPC.RES" file on my personnel Computer....i have installed 10g on my personnel computer...and not find any file named as "FMRPC.RES" only the simillar files i found is "FMRPCWEB.RES" and "FMRPCweb_UTF8.RES" , "FMRUSW.RES" ,"FMRWEB.RES" plz tell me which file i have to used to mape the key... I have five 'fmr*.res' files on my PC in "C:\DevSuiteHome_1\forms". They are: fmrpcweb.res, fmrpcweb_utf8.res, fmrusw.res, fmrweb.res, and fmrweb_utf8.res. The files fmrpcweb.res and fmrpcweb_utf8.res are identical. The files fmrweb.res and fmrweb_utf8.res are identical. The file fmrusw.res is not a 'text' file that looks 'open' to the edited. I compared fmrpcweb.res and fmrweb.res and they have differences but I am currently not in a position to test these differences. I will have to leave it up to you for the moment. I suggest you select a single line to be compared in the key help pop-up, for example, line 72 which contains: in fmrpcweb.res 114 : 0 : "F3" : 73 : "Duplicate Item" and in fmrweb.res 116 : 1 : "Shift+F5
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Susan Yeatts of Tampa sometimes went as long as a minute without breathing, before she awakened gasping. She was diagnosed with obstructive sleep apnea in 1990, but believes she had the problem since birth. "My mother said I snored so badly as an infant that she couldn't keep my bassinette next to her bed," said Yeatts, now 51 and a pharmacy researcher. A sleep study confirmed that she stopped breathing an average of 73 times an hour, all night long. "I was exhausted all the time," she said. "I never got deep sleep. I was always tired." Mild sleep apnea can usually be resolved with lifestyle changes like losing weight, not smoking, avoiding alcohol before bedtime and sleeping on your side instead of your back. Dental appliances worn during sleep that keep the lower jaw forward and the airway open, also help in some mild cases. Mild to moderate apnea may be treated with surgery, including removal of tissue from the back of the mouth and throat, including the uvula, tonsils and adenoids; plastic rod implants are also sometimes used to stiffen the soft palate, making it less likely to vibrate. When apnea is moderate to severe, the gold standard of treatment is continuous positive airway pressure, commonly known as CPAP. This is a machine that delivers air through a hose or tubing connected to a mask worn while you sleep. The mask fits over the nose or has prongs that fit inside the nose. The air pressure is just enough to keep the airway open and prevent apnea and snoring. Yeatts was prescribed CPAP right after her diagnosis, but found it cumbersome, difficult to sleep with and awkward, especially as a young woman. Still, she used it on and off for 20 years. "It worked," she admits, "But it's noisy and intrusive and it's for the rest of your life. Who wants that?" That was Holler's biggest objection, too. "I would have to use it for the rest of my life," he said. Plus, he found that he tossed and turned too much for CPAP, which "requires you to sleep in one position, on your back, and stay there.'' "I wanted a permanent solution," he said. Holler and Yeatts both turned to Tampa craniomaxillofacial surgeon Pat Ricalde for a radical procedure that moves the mouth, tongue and chin forward permanently to enlarge the airway. Maxillomandibular advancement, or MMA, isn't for everyone with apnea, said Ricalde, especially those doing well with CPAP or other conservative treatment. "The people who come to me have severe apnea and are desperate for a solution," she said. Her patients are so sleep-deprived, they aren't daunted by major surgery. MMA involves cutting several bones in the face and reconnecting them with small titanium screws and plates. It takes about four hours, requires at least two nights in the hospital and means missing work for two weeks. They can resume normal activities and diet in five to six weeks. The hardware is permanent, but won't set off security alarms at airports, Ricalde says of a frequently asked question. "Yes, the surgery is a big deal, but the condition—obstructive sleep apnea—is a big deal. It's more than just snoring. Their oxygen levels drop so low that, over time, it increases their risk of heart attacks, strokes and some cancers," said Ricalde. Dr. Tapan Padhya, co-director of the sleep disorders and snoring clinic at USF Health and Tampa General Hospital says MMA is "an appropriate, accepted surgery.'' But few of his patients who are eligible have it done, "usually because of the long recovery period or insurance issues." The cost can run about $40,000. Yeatts said it took a year before her insurance company would approve the procedure. She had the surgery six months ago. "It's made an amazing difference," she said. "I'm happier, more alert, I can stay awake later at night and I can breath easier." She still has some numbness in her bottom lip, but said it has been slowly improving. Holler had the surgery last April and also has some residual numbness in his lower lip and chin. "It's a weird feeling, but it was worth it," he sys. He snores much less now and his apnea episodes have dropped from 88 an hour to just three. He and his wife are able to sleep in the same room again and recently took a family vacation for the first time in years./* * Generated by class-dump 3.3.4 (64 bit). * * class-dump is Copyright (C) 1997-1998, 2000-2001, 2004-2011 by Steve Nygard. */ #import <SAObjects/SABaseClientBoundCommand.h> @class NSString; @interface SAAppsLaunchApp : SABaseClientBoundCommand { } + (id)launchAppWithDictionary:(id)arg1 context:(id)arg2; + (id)launchApp; - (BOOL)requiresResponse; @property(copy, nonatomic) NSString *launchId; - (id)encodedClassName; - (id)groupIdentifier; @end What's inside the Senate GOP health care bill Republicans released the text of their bill at an all-members meeting. — -- Seven weeks after the House of Representatives passed the American Health Care Act, Senate Republicans unveiled their version of the health care bill today. Here's how the Senate bill differs from the one passed by the House. Inside the Senate bill Funds two years of current Obamacare payments to insurers (which President Trump has repeatedly threatened to pull) to stabilize the insurance marketplace. Delays cuts to Medicaid. Eliminates Obamacare’s individual mandate and doesn’t include penalties for a lapse in coverage. Allows children to stay on parents’ plans through the age of 26. Incentivizes states to apply for waivers of the Essential Health Benefit rules. Some essential benefits include maternity care, drug abuse care and ambulances that are required in insurance plans under the current law. Recapping the House bill Prevents women from using federal tax credits to buy plans that cover abortion and temporarily blocks Planned Parenthood from receiving federal funds for one year. Lets states impose work requirements for Medicaid. Allows states to seek waivers from covering essential health benefits – including maternity care and emergency room trips. Allows states to waive an Obamacare regulation that prevented insurers from charging sicker consumers more, which would effectively undermine pre-existing conditions protections. Repeals Obamacare’s individual mandate but penalizes people who let their coverage lapse for 63 days. Replaces Obamacare’s income-based tax credits with age-based tax credits that don’t vary with local insurance costs. Adds $8 billion to high-risk pools for Americans with pre-existing conditions. Going forward The bill’s release follows months of speculation and contentious debate. Senate Democrats have criticized their Republican counterparts for working on the bill behind closed doors. Earlier this week, Sen. Al Franken, D-Minn., appearing on ABC News’ “Powerhouse Politics” podcast, noted that when crafting the Affordable Care Act, Republicans had a chance to offer changes. “In the Health Committee, I think 160 Republican amendments were accepted into the bill,” he said. “It was debated for 25 straight days before it was voted on. It was scored well in advance. This is a sham.” The Congressional Budget Office, which provides nonpartisan, quantitative analyses to Congress, will now evaluate the bill. A CBO score could come as soon as Friday. The CBO estimated that the version of the American Health Care Act passed by the House would leave 23 million more Americans uninsured by 2026 than under the Affordable Care Act. The office also estimated the bill would reduce federal deficits by $337 billion from 2017 to 2026. ABC News’ Mary Bruce contributed to this report.I am looking at a late 80's prostar 190 right now w/ 800 hours on it. I have heard that with the right amount of weight in these boats they will put up a huge wave. Just wondering what kind of weight you would have to run and would I just be getting into a ton of problems with this old of a boat?--- abstract: 'We study the question of whether or not it is possible to determine a finitely generated group $G$ up to some notion of equivalence from the spectrum ${\mathrm{sp}}(G)$ of $G$. We show that the answer is “No” in a strong sense. As a first example we present the collection of amenable 4-generated groups $G_\omega$, $\omega\in\{0,1,2\}^\mathbb N$, constructed by the second author in 1984. We show that among them there is a continuum of pairwise non-quasi-isometric groups with ${\mathrm{sp}}(G_\omega)=[-\tfrac{1}{2},0]\cup[\tfrac{1}{2},1]$. Moreover, for each of these groups $G_\omega$ there is a continuum of covering groups $G$ with the same spectrum. As a second example we construct a continuum of $2$-generated torsion-free step-3 solvable groups with the spectrum $[-1,1]$. In addition, in relation to the above results, we prove a version of the Hulanicki Theorem
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none of them have shown the ability to play inside.Search This Blog Posts The term DIY – Do It Yourself – has been around for over a century.Originally, it referred to those that would rely on themselves for everything from home repairs to various fix-it projects. In more contemporary times, it was the anthem for the punk rock and alternative music movements that discovered that bands did not have to depend on large, corporate record companies, booking agencies or management entities to start their careers.Instead, these bands could record and release their own music, book their own shows and take their music directly to the people without the corporate middleman. Education is no stranger to the DIY movement either.Indeed, much of the spirit of charter schools was the idea that a group of like-minded educators, parents or community members could start their own schools based on the needs of their students. So, what is the DIY movement mean now to the profession of education in this era of technology integration, increased relevance and enga… As a student, did you ever have a teacher that could talk the talk, but did not walk the walk? Well, I’ll never forget having on obese PE teacher in middle school.I am not here to discredit someone for being obese.Indeed, as an adult, I too have become overweight.The difference is that I’m not a PE teacher or someone who preaches health and fitness for a living.He would tell us to run when he could not run himself.I saw this as hypocritical and disingenuous. How many of you had an English teacher who couldn’t spell or made lots of grammatical errors?Again, I think it’s ok to make spelling or grammatical errors, unless you’re the person who teaches and preaches this for a living. Once I became a teacher, I worked hard not to repeat these examples.So, as a Journalism and Media teacher, I continued to write, publish and produce my own freelance work.Not only did that keep me fresh and relevant, but also gave me credibility.If my students were wrestling with story ideas, being edited,…Transosseous air contrast CT-guided needle biopsy of a cystic neoplasm. CT-guided fine-needle aspiration biopsy of a metastasis from an ovarian cystadenocarcinoma was performed using air contrast and a transosseous approach. Air contrast allowed identification of a papillary projection within the cyst, and the transosseous approach permitted direct and easy access to the lesion./* Distributed under the OSI-approved BSD 3-Clause License. See accompanying file Copyright.txt or https://cmake.org/licensing for details. */ #include "cmOptionCommand.h" #include "cmExecutionStatus.h" #include "cmMakefile.h" #include "cmMessageType.h" #include "cmPolicies.h" #include "cmProperty.h" #include "cmState.h" #include "cmStateSnapshot.h" #include "cmStateTypes.h" #include "cmStringAlgorithms.h" // cmOptionCommand bool cmOptionCommand(std::vector<std::string> const& args, cmExecutionStatus& status) { const bool argError = (args.size() < 2) || (args.size() > 3); if (argError) { std::string m = cmStrCat("called with incorrect number of arguments: ", cmJoin(args, " ")); status.SetError(m); return false; } // Determine the state of the option policy bool checkAndWarn = false; { auto policyStatus = status.GetMakefile().GetPolicyStatus(cmPolicies::CMP0077); const auto* existsBeforeSet = status.GetMakefile().GetStateSnapshot().GetDefinition(args[0]); switch (policyStatus) { case cmPolicies::WARN: checkAndWarn = (existsBeforeSet != nullptr); break; case cmPolicies::OLD: // OLD behavior does not warn. break; case cmPolicies::REQUIRED_ALWAYS: case cmPolicies::REQUIRED_IF_USED: case cmPolicies::NEW: { // See if a local variable with this name already exists. // If so we ignore the option command. if (existsBeforeSet) { return true; } } break; } } // See if a cache variable with this name already exists // If so just make sure the doc state is correct cmState* state = status.GetMakefile().GetState(); cmProp existingValue = state->GetCacheEntryValue(args[0]); if (existingValue && (state->GetCacheEntryType(args[0]) != cmStateEnums::UNINITIALIZED)) { state->SetCacheEntryProperty(args[0], "HELPSTRING", args[1]); return true; } // Nothing in the cache so add it std::string initialValue = existingValue ? *existingValue : "Off"; if (args.size() == 3) { initialValue = args[2]; } bool init = cmIsOn(initialValue); status.GetMakefile().AddCacheDefinition(args[0], init ? "ON" : "OFF", args[1].c_str(), cmStateEnums::BOOL); if (checkAndWarn) { const auto* existsAfterSet = status.GetMakefile().GetStateSnapshot().GetDefinition(args[0]); if (!existsAfterSet) { status.GetMakefile().IssueMessage( MessageType::AUTHOR_WARNING, cmStrCat(cmPolicies::GetPolicyWarning(cmPolicies::CMP0077), "\n" "For compatibility with older versions of CMake, option " "is clearing the normal variable '", args[0], "'.")); } } return true; } Many individuals throughout the world experience stressful lives. When these individuals aren’t aware of how to reduce, eliminate, or alleviate this stress, it can lead to other mental health issues. Unfortunately, depression is not uncommon. On a world-wide basis, it’s been determined that 350 million individuals experience some type of depression. While some men experience this condition, women are 70% more likely to do so. By the time they are 18 years of age, it’s been estimated that 11% of adolescents will have some form of depressive disorder. In order to learn how to cope with stress and resolve personal issues, therapy can be beneficial. Therapy can also assist individuals experiencing depression and other mental health issues. It’s interesting to note, however, that recent data indicates 50% of Americans that experienced depression didn’t seek Individual counseling or other treatment options. While some individuals may not seek help due to the stigma attached to men Welcome to our blog! Working out can be a drag! You need to constantly be looking for ways to keep it interesting. Browse our site for the latest tips and information on how to keep your workout routines and exercise healthy and exciting. Latest Gym News Error message: Atypical RSS/Atom feed or not supported by this plugin. Chalres Alexander An old friend of mine from high school just got liposuction, and she looks great. She used to sort of look like a monster, but now she looks like a much more attractive version of herself from high school.Influence of a variable Rayleigh scattering-loss coefficient on the light backscattering in multimode optical fibers. The recently developed diffraction technique of analytical investigation of the Rayleigh backscattering produced by an incident fundamental mode in a multimode optical fiber with an arbitrary refractive index profile is supplemented by taking into account the Rayleigh scattering-loss coefficient, which could be variable within the fiber cross section. The relative changes in various radial and azimuthal modes' excitation levels, due to some typical radial dependences of this coefficient, are computed for the quadratic- and step-index fibers. It is stated that the excitation efficiency could either rise or decay for different modes. The effect of the variable Rayleigh scattering-loss coefficient is shown to be more noticeable in the fibers with a quadratic refractive index profile, whereas it is negligible in actual multimode step-index fibers.SCREAMWORTHY... First... Let me state that only film/TV adaptations of King’s horror stories are considered for this list (this is Horror Central after all). Obviously if all of his work was under consideration then The Shawshank Redemption, Stand By Me, The Running Man, Hearts in Atlantis among many others, would almost undoubtedly be on the list. As a MASSIVE Stephen King fan, it was tough enough just pruning his horror work alone down to ten, never mind everything else. John Carpenter hit the nail on the proverbial head in 1978 with his fantastic film, Halloween. Now, without getting into every
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7*y**2 - 13669*y - 3906 = 0. -2/7, 1953 Factor 5*k**2 - 1390*k + 1385. 5*(k - 277)*(k - 1) Factor -3*m**4 - 21*m**3 - 42*m**2 - 24*m. -3*m*(m + 1)*(m + 2)*(m + 4) Factor 7*s**5 - 31*s**4 + 54*s**3 - 46*s**2 + 19*s - 3. (s - 1)**4*(7*s - 3) Solve -2*n**4 - 10*n**3 + 314*n**2 + 1882*n + 1560 = 0. -12, -5, -1, 13 Factor -26*m**2/17 - 8*m/17. -2*m*(13*m + 4)/17 Determine f so that -3*f**5/8 - 45*f**4/8 - 123*f**3/4 - 72*f**2 - 60*f = 0. -5, -4, -2, 0 Factor 100*q**2 - 240*q + 144. 4*(5*q - 6)**2 Suppose -20*w**5 + 75*w**4 - 80*w**3 + 15*w**2 + 10*w = 0. Calculate w. -1/4, 0, 1, 2 What is f in 2*f**2/15 + 16*f/15 - 6/5 = 0? -9, 1 Factor o**4/3 + 4*o**3/3 + 2*o**2 + 4*o/3 + 1/3. (o + 1)**4/3 Factor 4*i**3 - 4*i**2 - 32*i + 48. 4*(i - 2)**2*(i + 3) Find k such that -63*k**4/8 + 57*k**3/8 + 69*k**2/8 - 57*k/8 - 3/4 = 0. -1, -2/21, 1 Solve a**5 + 6*a**4 - 32*a**3 - 126*a**2 + 31*a + 120 = 0 for a. -8, -3, -1, 1, 5 Factor 3*m**4/7 - 117*m**3/7 + 333*m**2/7 - 327*m/7 + 108/7. 3*(m - 36)*(m - 1)**3/7 Let -h**2 + 100*h + 2124 = 0. Calculate h. -18, 118 Solve -1200*z**2 - z = 0 for z. -1/1200, 0 Factor 3*b**2/4 - 39*b + 1521/4. 3*(b - 39)*(b - 13)/4 Solve -18*t**3/5 + 294*t**2/5 - 208*t - 1352/5 = 0. -1, 26/3 Factor -2*i**4 - 20*i**3 + 382*i**2 - 360*i. -2*i*(i - 9)*(i - 1)*(i + 20) Solve u**3 + 7*u**2 - 10*u - 16 = 0 for u. -8, -1, 2 Suppose -3*d**2 + 51*d - 156 = 0. What is d? 4, 13 Factor 4*o**5/5 - 32*o**4/5 + 84*o**3/5 - 72*o**2/5. 4*o**2*(o - 3)**2*(o - 2)/5 Solve -34*s**3/3 - 10*s**2/3 + 8*s = 0. -1, 0, 12/17 Factor -2*i**3/3 + 4*i**2 - 22*i/3 + 4. -2*(i - 3)*(i - 2)*(i - 1)/3 Determine k so that k**3/3 + 5*k**2/3 + k - 3 = 0. -3, 1 Let -3*b**2 + 732*b - 729 = 0. What is b? 1, 243 Factor -4*l**2 + 56*l - 160. -4*(l - 10)*(l - 4) Factor -69*z**3/2 - 623*z**2/2 - 492*z - 14. -(z + 2)*(z + 7)*(69*z + 2)/2 Factor w**3/2 - 3*w**2/2 - w/2 + 3/2. (w - 3)*(w - 1)*(w + 1)/2 Factor -9*a**3/4 - 579*a**2/4 + 389*a/4 - 65/4. -(a + 65)*(3*a - 1)**2/4 Factor 2*a**2/5 + 152*a/5 + 2888/5. 2*(a + 38)**2/5 Factor 3*u**2/7 + 39*u/7 + 66/7. 3*(u + 2)*(u + 11)/7 Factor -3*q**3 + 378*q**2 - 15795*q + 218700. -3*(q - 45)**2*(q - 36) Factor 1296*q**4/7 - 216*q**2/7 + 48*q/7 - 3/7. 3*(2*q + 1)*(6*q - 1)**3/7 Determine g, given that 3*g**4 - 24*g**3 + 54*g**2 - 81 = 0. -1, 3 Suppose 5*r**5/3 - 160*r**4/3 + 330*r**3 - 680*r**2/3 - 995*r/3 + 280 = 0. Calculate r. -1, 1, 7, 24 Suppose -3*a**4 + 45*a**3 + 111*a**2 - 153*a = 0. Calculate a. -3, 0, 1, 17 Solve -i**2 + 20*i - 36 = 0 for i. 2, 18 Suppose 2*s**2/5 + 88*s/5 - 954/5 = 0. What is s? -53, 9 Find a, given that -a**5 + 7*a**4 - 19*a**3 + 25*a**2 - 16*a + 4 = 0. 1, 2 Factor -1089*l**2 + 15180*l - 52900. -(33*l - 230)**2 Let 22*q**3 - 67*q**2/3 - 56*q/3 + 4 = 0. Calculate q. -2/3, 2/11, 3/2 Factor 2*d**4/9 + 326*d**3 + 159414*d**2 + 25984482*d. 2*d*(d + 489)**3/9 Determine w so that -3*w**3/5 - 138*w**2/5 + 3*w/5 + 138/5 = 0. -46, -1, 1 Suppose -3*v**4 + 69*v**3 - 567*v**2 + 1911*v - 2058 = 0. Calculate v. 2, 7 Factor -r**2/6 + 31*r/3 - 961/6. -(r - 31)**2/6 Determine h so that h**5/6 + 29*h**4/6 + 48*h**3 + 530*h**2/3 + 400*h/3 = 0. -10, -8, -1, 0 Factor -p**3/2 - 14*p**2. -p**2*(p + 28)/2 Find f, given that -2*f**5/3 - 2*f**4/3 = 0. -1, 0 Solve -z**4/7 - 10*z**3/7 + 23*z**2/7 - 12*z/7 = 0 for z. -12, 0, 1 Factor -2*o**2/15 + 12*o + 368/15. -2*(o - 92)*(o + 2)/15 Solve 4*j**2 + 20*j + 24 = 0 for j. -3, -2 Factor -m**3 - 173*m**2 + 1065*m - 1611. -(m - 3)**2*(m + 179) Solve -4*q**2 + 200*q - 900 = 0. 5, 45 Suppose 2*q**4 + 28*q**3 + 48*q**2 = 0. Calculate q. -12, -2, 0 Find x such that x**4/4 - x**3/2 - 3*x**2 - 7*x/2 - 5
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listfor selected value to controller on selected item changed Trying to pass the selected value which is studentid in this case to BeginForm. View @using (Html.BeginForm("DDSubmit", "Home",new { id=Model.studentID}, FormMethod.Post)) { @Html.DropDownListFor(m => m.studentID, Model.DDList, "Please Select",new { onchange = "this.form.submit();" }) } Controller Action public ActionResult DDSubmit(int id) { var info = (from r in entity.STUDENTS where r.Student_Id == id select r).ToList(); return View(info); } Model public class DDModel { public List<SelectListItem> DDList { get; set; } public int studentID { get; set; } public string studentName { get; set; } } A: finally figured out View @using (Html.BeginForm("DDSubmit", "Home", FormMethod.Post)) { @Html.DropDownListFor(m => m.studentID, Model.DDList, "Please Select",new { onchange = "this.form.submit();" }) } Action public ActionResult DDSubmit(DDModel ddlist) { int id = ddlist.studentID; var info = (from r in entity.STUDENTS where r.Student_Id == id select r).ToList(); return View(info); } Q: How to write the following regex in Flex? I'm trying to define a rule in flex that will capture a "multiline string". A multiline string is a string that starts with three apostrophes: ''', ends with three apostrophes, and can span over multiple lines. For example: '''This is an example of a multiline string''' So my attempt at this was this: %{ #include<iostream> using std::cout; using std::endl; %} MULTI_LN_STR '''(.|\n)*''' %% {MULTI_LN_STR} {cout<<"GotIt!";} %% int main(int argc, char* argv[]) { yyin=fopen("test.txt", "r"); if (!yyin) { cout<<"yyin is NULL"<<endl; return 1; } yylex(); return 0; } Which works for the input: '''This is a multi line string!''' This is some random text The output is: GotIt! This is some random text but does not work (or, to be more accurate, produces wrong output) for this input: '''This is a multi line string!''' This is some random text '''and this is another multiline string''' Which produces: GotIt! This reason is because my rule says: "scan for three apostrophes, followed by any possible character, followed by three apostrophes", but rather, it should say: "scan for three apostrophes, followed by any possible character except three apostrophes, followed by three apostrophes". How can I do that? A: For a simple negation like this, it is relatively easy to construct a regular expression: "'''"([^']|'[^']|''[^'])*"'''" 185 Kan. 620 (1959) 347 P.2d 369 THE BOARD OF EDUCATION OF THE CITY OF HERINGTON OF THE STATE OF KANSAS, Appellee, v. BERT L. THOMPSON, JR., FRANCES K. THOMPSON, HELEN THOMPSON SANDERSON, et al., Appellants. No. 41,479 Supreme Court of Kansas. Opinion filed December 12, 1959. Charles W. Bradshaw, of Abilene, argued the cause and Horace A. Santry, of Salina, was with him on the briefs for the appellants. Howard W. Harper, of Junction City, argued the cause, and Lee Hornbaker, William D. Clement and Richard F. Waters, all of Junction City, were with him on the briefs for the appellee. The opinion of the court was delivered by JACKSON, J.: The Board of Education filed suit in the district court to quiet title to real estate against the appellants as defendants. After filing a motion to strike and a motion to make the petition *621 more definite and the overruling of said motions by the trial court, defendants filed a demurrer to plaintiff's petition upon the grounds: 1. That several causes of action were improperly joined in said petition. 2. That the petition did not state facts sufficient to constitute a cause of action. The trial court overruled the demurrer and gave defendants time to answer. Instead, defendants appealed the order of the court overruling the demurrer to this court. It may be said that defendants do not argue in their brief the above motions or that there is any merit in the first ground specified in the above demurrer. The sole question now before the court is whether the petition stated a cause of action. The Board of Education in its petition alleged that it was the owner of the described real estate in Dickinson county in fee simple and was in possession thereof; that it had been in open and adverse possession of the real estate for more than fifteen years under and by virtue of a deed dated December 11, 1905, from Bert L. Thompson and Edith M. Thompson, then husband and wife. A copy of the deed was attached to the petition as an exhibit, and it is shown that the granting clause thereof reads in part as follows: "All of Block Number Ten (10) in Thompson's Addition to the City of Herington, to be occupied and used by said party of the second part its successors and assigns, for public schools as provided by the laws of the State of Kansas now in force or hereafter to be enacted, and for no other purpose." The petition of the Board of Education contains the following concluding paragraph preceding the prayer: "The above named defendants, and each of them, claim some title, estate or interest in or lien upon the real estate above described, adverse to the plaintiff, the exact nature of which claim is unknown to the plaintiff, but none of the said defendants have any title, estate or interest in the said real estate, or lien thereon, and said claims are void and wholly inferior and junior to the title and right of possession of the plaintiff to said real estate and constitute a cloud upon plaintiff's title." Among the opening paragraphs of the brief of the appellants in this court, we find the following: "The attention of the court is especially invited to the fact that the only parties to this suit are the grantee and the heirs of the grantor of the deed to be construed, and that the grantee seeks to quiet title for all purposes against its grantor." The very evident trouble with the above statement at the very outset is that these facts do not appear on the face of the petition. While these demurring defendants are named in the petition, neither *622 their identity nor any right or claim of title belonging to them is disclosed in the petition. Instead, the petition in effect asks that defendants answer and set up any claim of title which they may have to the real estate in question. One of the oldest and best settled rules of pleading is that a demurrer will reach only facts which appear in the pleading demurred to. If certain facts are necessary for the court to consider in passing upon a question of law and are not contained in the petition, a defendant must answer and allege the pertinent and necessary facts. This rule was better understood perhaps, or at least was fraught with more danger to the party demurring before the enactment of the provisions of the civil code allowing defendant to plead over after the overruling of a demurrer to the petition. Yet, even in modern practice, ill-advised demurrers waste time of the parties and the courts, and increase the cost of litigation. One of the first cases in which this court discussed the rule that a demurrer reached only the facts appearing on the face of the petition appears to have been Mayberry v. Kelley, 1 Kan. 116. The same principle has been reiterated many times since the Mayberry case. A few of the later cases may be mentioned: Winfield Town Co. v. Maris, 11 Kan. 128; Northrup v. Willis, 65 Kan. 769, 70 Pac. 879; Manufacturing Co. v. Keckley, 77 Kan. 797, 90 Pac. 781; Riverside v. Bailey, 82 Kan. 429, 108 Pac. 796; Runnels v. Montgomery Ward & Co., 165 Kan. 571, 195 P.2d 571; Lee v. Beuttel, 170 Kan. 54, 223 P.2d 692; Kendall v. Elliot, 177 Kan. 630, 281 P.2d 1088; Anderson Cattle Co. v. Kansas Turnpike Authority, 180 Kan. 749, 308 P.2d 172; Kleppe v.
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Product Dimensions:Width: 43'' Height: 38'' Depth: 43'' Finish: Tan Unique Features: Coil enhanced cushions as well as the coil enhanced frame offer added longevity.Semi-attached back cushions.Four turned front legs, two on the front rail with two end legs receased off front rail. Error Enter Your Zip Code Good news! Available for Pick-up Only Tailor our selection to make sure you see only items that can be delivered to you. Inform you if the item is currently in stock. Offer you special pricing that may only be available in some areas. Help you find a local showroom in case you want to see an item in person. Show you estimated delivery dates without having to checkout. Levin Furniture respects your privacy and will not share this information with anyone. Please wait... or www.Levin.ca is accepting online orders delivered to your zip code. Although you live outside our delivery area, we invite you to order online and pick up your merchandise at your closest store or find another store here. Your closest store: Regular Store Hours: Our delivery area continues to grow. As a registered user, we'll notify you if delivery becomes available in your neighborhood. In the meantime, we hope you enjoy our selection of merchandise that is available for pick-up. Our delivery area continues to grow. Register with us today and we'll notify you as soon as delivery becomes available in your location.CMFRI teams up with ISRO to collect field level data of wetlands A mobile app has been developed to collect complete datasets on smaller wetlands across the coastal region of the country. The app was developed by the Space Applications Centre of Indian Space Research Organisation on a request from the Central Marine Fisheries Research Institute (CMFRI) in line with a memorandum of understanding between them. The mobile app is aimed to generate a centralised digital database of the smaller wetlands (2.2 ha or below) across the country. Such smaller wetlands cover an area of more than five lakh hectares across the country, while Kerala has 2,592 smaller wetlands. The app will be used to collect field level data of the wetlands that include geospatial profile, size, water and soil quality, farmed species, pollution status, illegal construction and biodiversity specialities. “The concept is to integrate field-level regional wetland data to geospatial datasets so as to enable comprehensive monitoring system in the wake of climate change and wetland vulnerabilities”, said CMFRI director A. Gopalakrishnan during the launch of the mobile app on Monday. Game changer The app could become a game changer in making wetlands resilience by bridging the gap between satellite and ground data, he said. “Continuous monitoring will help provide village-level real time advisories for aqua-farmers and alerts on climatic phenomenon in the future”, he said. Climate related events such as floods have changed the physio-chemical profile of wetlands. “Many fish farmers and fishermen suffered economic loss due to loss of cages, salinity changes in aquafarms and coastal ecosystem changes,” he said. Common platform A digital common platform on the health status of wetlands of the country could easily help understand such vulnerable regions, he added. The initiative of monitoring the wetlands is carried out by the National Innovations in Climate Resilient Agriculture (NICRA) project wing of the CMFRI. The data collection using the mobile app will be done by registered researchers, farmers and stakeholders while the experts associated with the task will validate the data and will be stored them in the central database.Determination of the wax ester content in olive oils. Improvement in the method proposed by EEC regulation 183/93. A simpler and faster procedure than the official one described in document IV of European Economic Community Regulation 183/93 is proposed. The wax ester fraction is isolated from triglycerides using a commercially available silica gel column and carbon tetrachloride as eluent. The recovered wax ester fraction, with the addition of a suitable internal standard solution, is analyzed by gas chromatography. A column with a 65% phenyl methyl silicone stationary phase allows a satisfying separation of wax ester fraction in comparison with both a steryl ester and a light fraction eluted before the internal standard. Furthermore, also the single components of the wax ester fraction are suitably separated.<!DOCTYPE HTML> <!-- NewPage --> <html lang="en"> <head> <!-- Generated by javadoc --> <title>KeyName (Java SE 12 &amp; JDK 12 )</title> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8"> <meta name="keywords" content="javax.xml.crypto.dsig.keyinfo.KeyName interface"> <meta name="keywords" content="getName()"> <link rel="stylesheet" type="text/css" href="../../../../../../stylesheet.css" title="Style"> <link rel="stylesheet" type="text/css" href="../../../../../../jquery/jquery-ui.css" title="Style"> <script type="text/javascript" src="../../../../../../script.js"></script> <script type="text/javascript" src="../../../../../../jquery/jszip/dist/jszip.min.js"></script> <script type="text/javascript" src="../../../../../../jquery/jszip-utils/dist/jszip-utils.min.js"></script> <!--[if IE]> <script type="text/javascript" src="../../../../../../jquery/jszip-utils/dist/jszip-utils-ie.min.js"></script> <![endif]--> <script type="text/javascript" src="../../../../../../jquery/jquery-3.3.1.js"></script> <script type="text/javascript" src="../../../../../../jquery/jquery-migrate-3.0.1.js"></script> <script type="text/javascript" src="../../../../../../jquery/jquery-ui.js"></script> </head> <body> <script type="text/javascript"><!-- try { if (location.href.indexOf('is-external=true') == -1) { parent.document.title="KeyName (Java SE 12 & JDK 12 )"; } } catch(err) { } //--> var data = {"i0":6}; var tabs = {65535:["t0","All Methods"],2:["t2","Instance Methods"],4:["t3","Abstract Methods"]}; var altColor = "altColor"; var rowColor = "rowColor"; var tableTab = "tableTab"; var activeTableTab = "activeTableTab"; var pathtoroot = "../../../../../../"; var useModuleDirectories = true; loadScripts(document, 'script');</script> <noscript> <div>JavaScript is disabled on your browser.</div> </noscript> <header role="banner"> <nav role="navigation"> <div class="fixedNav"> <!-- ========= START OF TOP NAVBAR ======= --> <div class="topNav"><a id="navbar.top"> <!-- --> </a> <div class="skipNav"><a href="#skip.navbar.top" title="Skip navigation links">Skip navigation links</a></div> <a id="navbar.top.firstrow"> <!-- --> </a> <ul class="navList" title="Navigation"> <li><a href="../../../../../../index.html">Overview</a></li> <li><a href="../../../../../module-summary.html">Module</a></li> <li><a href="package-summary.html">Package</a></li> <li class="navBarCell1Rev">Class</li> <li><a href="class-use/KeyName.html">Use</a></li> <li><a href="package-tree.html">Tree</a></li> <li><a href="../../../../../../deprecated-list.html">Deprecated</a></li> <li><a href="../../../../../../index-files/index-1.html">Index</a></li> <li><a href="../../../../../../help-doc.html">Help</a></li> </ul> <div class="aboutLanguage"><div style="margin-top: 14px;"><strong>Java SE 12 &amp; JDK 12</strong> </div></div> </div> <div class="subNav"> <div> <ul class="subNavList"> <li>Summary:&nbsp;</li> <li>Nested&nbsp;|&nbsp;</li> <li>Field&nbsp;|&nbsp;</li> <li>Constr&nbsp;|&nbsp;</li> <li><a href="#method.summary">Method</a></li> </ul> <ul class="subNavList"> <li>Detail:&nbsp;</li> <li>Field&nbsp;|&nbsp;</li> <li>Constr&nbsp;|&nbsp;</li> <li><a href="#method.detail">Method</a></li> </ul> </div> <ul class="navListSearch"> <li><
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myCRM to do and how we'd like it to look. Now we're ready to start building the user interface using smartGWT's layout containers and widgets. In this post, we'll: Select the smartGWT layout containers needed to divide the browser window into regions Implement the smartGWT layout containers Test the application in development mode 1. Select the smartGWT layout containers First, take a look at the smartGWT Showcase and the types of widgets that you can use to manage layout. This is analogous to laying out your web page in HTML using nested div elements or tables. For myCRM, we'll use a combination of nested horizontal and vertical layout containers. smartGWT uses a default theme called "Enterprise Gray", later on we'll look at how to change the default theme and how to modify the appearance of widgets using CSS. 2. Implement the smartGWT layout containers In the area at the top of the browser window we've decided to place a masthead. A masthead is where you place important information, like the name of the application and a logo. Most of the UI is displayed as soon as myCRM starts up so for now we'll implement our widgets in the onModuleLoad method of the application's entry point class.Tuesday, February 9, 2010 I really haven't been in a blogging mood, so sorry it's been quiet around here. Isn't this the most awesome tape dispenser you have ever laid your eyes on? Well, I think it is and I purchased it with some of my birthday cash :) Now I just need to go get some tape for it. It will make me happy every time I need some tape now. I had a nice weekend, Casey's Mom took us to lunch at the Olive Garden for my birthday, yummy. I cleaned up my last show of the week (wow I was busy with shows). My book I had ordered for my birthday came in the mail yesterday. This was kinda cute, Casey was home from work before the girls and I were home from running some errands, and the package with my book was sitting on the doorstep. Casey hurried and opened it and wrapped the book up before I got home, I can just imagine him scrambling to hurry and wrap it, we didn't get home long after he did :) And I ordered this necklacewith some birthday cash. I just found out that my 3 best art shows that I participate in are going to have the same show dates for spring so I am going to be a busy girl getting ready to do three shows at the same time, it will be a first. I have done two at the same time, we'll see how three at the same time goes :) I am excited for Thursday, I am going to a knitting class taught by Kelly. I can't wait! Enough ramblings for now, I hope you had a lovely weekend, and have a great day! 5 comments: Don't think I am weird but at first look I thought that frog was a razor frog. I couln't figure out how you were going to shave with it!! Weird I know!!! I think it is cute now that I know what it is for!!!Friday, 24 October 2014 The Death of Queen Jane Following her sickness in the night, Jane Seymour’s confessor came to her in the morning of 24 October 1537. By 8am he was preparing to administer the sacrament of extreme unction, which involved anointing with oil and was given to those who were in grave peril of their lives. In his nursery only a short walk away in Hampton Court Palace, little Prince Edward – who was only twelve days old – was about to lose his mother. The ceremony evidently gave Jane some comfort. Later that day, Sir John Russell was able to report that she was ‘somewhat amended, and if she ‘scape this night, the physicians be in good hope that she be past danger’. Jane’s sickness had already gone on for such a long time that those around her could not see how she could remain in that condition – she had to either improve or die. Any hopes of her recovery were vain, however. At 8pm, twelve hours after she received extreme unction, the Duke of Norfolk sat down in his chamber at Hampton Court to write to Thomas Cromwell, stating ‘I pray you to be here tomorrow early to comfort our good master, for as for our mistress there is no likelihood of her life, the more pity, and I fear she shall not be alive at the time ye shall read this’. Norfolk was right and the queen slipped quietly away in the night. The death of Jane Seymour had been expected for more than a week but, as she lingered, those around her continued to hope that she might recover. Henry VIII, who was close by at Hampton Court, also grieved for his wife, although he took some consolation in the survival of his son. In a letter, written to Francis of France in response to congratulations on Edward’s birth, he commented that ‘Divine Providence has mingled my joy with the bitterness of the death of her who brought me this happiness’. In dying at the moment that Henry loved her the most, Jane retained a special place in his heart. He gave her a royal funeral at Windsor and, in time, asked to be buried with her himself. The couple lie together today. Although it is a romantic gesture, it should be pointed out that there was no other wife that Henry could have asked to be buried with. He denied that he had ever been married to Catherine of Aragon, Anne Boleyn and Anne of Cleves, while Catherine Howard lay buried as an executed traitor in the Tower. Henry’s last wife, Catherine Parr, was, of course, still alive. The relationship of Henry VIII and Jane Seymour was no great love affair but, with hindsight, it came to take on more significance for the king as he continued to suffer matrimonial disappointments. Jane, as the mother of his son, came to be looked upon as his true queen – the woman with whom he chose to be depicted in the great painting of his family which can be seen at Hampton Court where Jane died. Jane Seymour, the third wife of Henry VIII, was cut off at the moment of her greatest triumph, dying on 24 October 1537 before she had even reached her thirtieth birthday. Jane Seymour from a later engraving. The cause of her death - her baby - is depicted beneath the picture. About Me I'm an author and historian, specialising on the queens of England and the Tudor period. I love all things historical, training as an archaeologist before switching to historical research. I am currently carrying out academic research at King's College, London. I have written several books, including biographies of four of Henry VIII's wives, Margaret Beaufort, Bessie Blount and The Boleyn WomenVoluntary and controlled weight loss can reduce symptoms and proton pump inhibitor use and dosage in patients with gastroesophageal reflux disease: a comparative study. A wide variety of pieces of evidence has suggested that obesity is associated with a significant increase in the risk for gastroesophageal reflux disease (GERD) symptoms and its complications. The aim of this study was to evaluate the effect of weight loss on reflux symptoms in overweight/obese patients with proven GERD. We enrolled overweight/obese patients with typical GERD symptoms and erosive esophagitis. At baseline, patients underwent detailed reflux symptoms evaluation and anthropometric assessment, and were divided into two treatment groups: group A received proton pump inhibitor (PPI) and a personalized hypocaloric diet and aerobic exercise; and group B received PPI and a 'standard of care diet'. The dietetic treatment was considered effective if at least 10% of weight loss was achieved within 6 months. All patients were evaluated in terms of anthropometric data, GERD symptoms, and PPI use. In group A, mean body mass index (BMI) decreased from 30.3 ± 4.1 to 25.7 ± 3.1 (P < 0.05), and mean weight decreased from 82.1 ± 16.9 kg to 69.9 ± 14.4 kg (P < 0.05). In group B, there was no change in BMI and weight. Symptom perception decreased (P < 0.05) in both groups during PPI therapy, but a higher improvement was recorded in group A. In group A, PPI therapy was completely discontinued in 27/50 of the patients, and halved in 16/50. Only 7/50 continued the same PPI dosage. In group B, 22/51 halved the therapy and 29/51 maintained full dosage of therapy, but none was able to discontinue PPI due to a symptom recurrence. Overall, weight loss of at least 10% is recommended in all patients with GERD in order to boost the effect of PPI on reflux symptom relief and to reduce chronic medication use.Blog Carpet Materials: Wool or Synthetic? If you’re looking at installing new carpet at your home or office, at some point you’ll be faced with the decision of wool carpet or synthetic carpet. Both options have their own benefits, but much of the choice will guided by your...Celebrating their 4th Anniversary with 3 days (Sept 17th, 18th and 19th) of Junction Octoberfest : They launch their new brew ZOO Berliner Weisse September 17th with Bavarian Bratwurst by Crown & Anchor Food and Fresh Handmade Pretzels plus 12 German Festbiers #OnTap and #On
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ingot, joita aiheutui Parmalatin, Enronin, WorldComin ja muiden yritysten tapauksessa. Nämä kaikki julkaisivat aikanaan neljännesvuosikatsauksia, ja lopputuloksen voimme nähdä – älkäämme siis rasittako yrityksiä tuottamattomilla toimilla. Toiseksi oikeudellisten ja sisämarkkina-asioiden valiokunta piti tärkeänä, että direktiivi on sähköistä kaupparekisteriä koskevan direktiivin mukainen. Sisällytimme tähän direktiiviin lausekkeen, jonka nojalla jäsenvaltiot voivat perinteidensä mukaisesti säätää vaadittujen tietojen julkaisemisesta Internetin sijasta muissa tiedotusvälineissä. Onnistuimme sisällyttämään tämän säännön myös avoimuusdirektiiviin. Mielestäni näin varmistetaan, että jäsenvaltioiden lainsäätäjät voivat käsitellä kahta direktiiviä, joissa on samankaltainen sisältö, samalla tavalla. Pidämme tätä tärkeänä. Oikeudellisten ja sisämarkkina-asioiden valiokunta on lisäksi tyytyväinen velkapapereita koskevaan ratkaisuun. Oikeudellisten ja sisämarkkina-asioiden valiokunnassa käytyjen neuvottelujen tulos sai meidät huolestumaan siitä, että saattaisimme joutua IAS:n täytäntöönpanoa koskevassa kysymyksessä epäedulliseen asemaan Yhdysvaltojen kanssa käytävissä neuvotteluissa. Tämä kuitenkin estetään mielestäni nyt laaditulla aiempien oikeuksien rajoitettua säilyttämistä koskevalla säännöllä, ja neuvotteluasemamme ei ole aiempaa huonompi. Me vain teemme asiat hankalammaksi niille, jotka jo ovat Euroopassa. Kaiken kaikkiaan olen tyytyväinen tähän tulokseen ja kiitän erittäin lämpimästi esittelijäkollegoitani ja varjoesittelijöitä yhteistyöstä. Karas (PPE-DE ).    – Arvoisa puhemies, arvoisa komission jäsen Villiers, jäsen Skinner, aluksi totean, että kumpikin direktiivi on osa rahoituspalveluja koskevaa toimintasuunnitelmaa, ja näin ollen ne auttavat lujittamaan ja toteuttamaan sisäisiä rahoitusmarkkinoita. Toiseksi haluan todeta, että kumpikin direktiivi on suuri saavutus parlamentille ja parlamentaariselle yhteispäätösmenettelylle. Kolmanneksi nykyisessä muodossaan kummassakin direktiivissä on muutettu olennaisesti sekä komission luonnosta että yhteistä kantaa ja tuotu nämä lähemmäksi parlamentin näkemystä. Avoimuusdirektiivistä onkin jo todettu, että komission ehdotus EU:n pörssilistoilla olevien yritysten velvoittamisesta laatimaan neljännesvuosikatsauksia on nyt saatu pois päiväjärjestyksestä ja aivan perustellusti. Lainoja koskevia avoimuusvaatimuksia on parannettu huomattavasti. Nyt sovitulla yritystietojen julkaisemista koskevalla sanamuodolla varmistetaan, että jäsenvaltiot voivat vaatia omia yrityksiään julkaisemaan tiedot painetussa muodossa. Vaatimus tietojen samanaikaisesta julkaisemisesta on poistettu. Sijoituspalveludirektiivistä voin sanoa ainoastaan sen, että olisin ollut tyytyväisempi, jos 27 artiklassa olisi määritetty toimeksiannon tarkka koko tai jos johdanto-osan 49 kappale olisi poistettu. On kuitenkin tärkeää, että mietinnön avulla olemme onnistuneet löytämään kultaisen keskitien erilaisten kansallisten etunäkökohtien, Euroopan sisämarkkinoita koskevien etujen ja egoististen pyrkimystemme välillä, ja tästä kiitän lämpimästi esittelijä Villiersiä. Hänen ansiostaan kolme rahoitusmarkkinoiden kannalta erittäin tärkeää valtiota – Yhdistynyt kuningaskunta, Tanska ja Ruotsi – ovat nyt mukana, vaikka ne eivät alun perin kannattaneet yhteistä kantaa, ja markkinaosapuolet voivat nyt hyödyntää parempaa direktiiviä. Katiforis (PSE ).    Arvoisa puhemies, hyvät parlamentin jäsenet, sekä avoimuusvaatimusten yhdenmukaistamista että rahoituspalveluja koskevalla direktiivillä saatetaan tänään päätökseen vaikea prosessi, joka on vaatinut rahoituspalvelujen osalta valtavia ponnistuksia erityisesti esittelijä Villiersiltä. Tähän asiaan liittyy valtavia teknisiä ja poliittisia ongelmia, enkä usko, että prosessia olisi saatu päätökseen ilman hänen suunnatonta uutteruuttaan. Sen vuoksi haluan onnitella esittelijää siitä, että hän on tehnyt niin kovasti töitä. Se, että saamme tämän prosessin tänään lopultakin päätökseen, merkitsee parlamentille sekä talous- ja raha-asioiden valiokunnalle suurta saavutusta ja osoittaa, että jos lainsäädännön hyväksyminen joskus viivästyy, se ei johdu parlamentin velttoudesta. Sijoituspalveluja koskevan direktiivin – josta haluaisin sen varjoesittelijänä puhua enemmän – tarkoituksena on elvyttää rahoitusalalla toimivia yrityksiä koskeva EU:n laajuinen toimilupa. Tämä toimilupajärjestelmä ei ole tietenkään uusi asia, mutta se oli vanhentunut, koska kansallisten lainsäädäntöjen väliset erot aiheuttivat ongelmia yritysten rajatylittävässä liiketoiminnassa ja tämän vuoksi tietenkin myös pääoman vapaassa liikkuvuudessa. Uudessa direktiivissä ehdotetaan johdonmukaista ja yhdenmukaistettua sijoittajansuojaa koskevia toimia erityisesti piensijoittajia varten eri jäsenvaltioissa. Siinä ehdotetaan myös tasapuolisia ehtoja arvopaperipörssien ja sijoitusyhtiöiden väliselle kilpailulle. Tämä on yksi hankalimmista ja monimutkaisimmista kysymyksistä, joita meidän on käsiteltävä. Tässä on nimittäin kysymys markkinoilla nähtävästä uudesta ilmiöstä, jossa kokonaiset arvopaperipörssit muuttuvat yksityisyrityksiksi ja kokonaiset yksityisyritykset toimivat eräänlaisina pienimuotoisina arvopaperipörsseinä, jotka selvittävät valtavat määrät toimeksiantoja.
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”) that should be categorized into an album – for example if you have a Sketches album and a Concept Art album, you want them to be visually separated into folders. You can now do this with the Album View feature. How to change to Album View Visit your community profile. Click the “Portfolio display options” button Change to “Show albums”, click “Save” To take advantage of the Albums feature, Manage your portfolio and drag and drop artwork into albums on the left.// // SPPreferences.h // DBSmartPanels // // Created by Dave Blundell on 10/19/14. // Copyright (c) 2014 Dave Blundell. All rights reserved. // #import <Foundation/Foundation.h> typedef enum : NSUInteger { SPAutohidingBehaviorNone = 0, SPAutohidingBehaviorConservative = 1, SPAutohidingBehaviorAggressive = 2, SPAutohidingBehaviorCustom = 3, SPAutohidingNumBehaviors = 4 } SPAutohidingBehavior; @interface SPPreferences : NSObject @property (nonatomic) SPAutohidingBehavior autohidingBehavior; @property (nonatomic) BOOL hideDebuggerWhenTypingBegins; @property (nonatomic) BOOL dontHideDebuggerWhileDebuggingWhenTypingBegins; @property (nonatomic) BOOL hideNavigatorWhenTypingBegins; @property (nonatomic) BOOL hideUtilitiesWhenTypingBegins; @property (nonatomic) BOOL restoreEditorModeWhenOpeningTextDocument; @property (nonatomic) BOOL restoreDebuggerWhenOpeningTextDocument; @property (nonatomic) BOOL hideNavigatorWhenOpeningTextDocument; @property (nonatomic) BOOL hideUtilitiesWhenOpeningTextDocument; @property (nonatomic) BOOL switchToStandardEditorModeWhenOpeningInterfaceFile; @property (nonatomic) BOOL hideDebuggerWhenOpeningInterfaceFile; @property (nonatomic) BOOL dontHideDebuggerWhileDebuggingWhenOpeningInterfaceFile; @property (nonatomic) BOOL hideNavigatorWhenOpeningInterfaceFile; @property (nonatomic) BOOL showUtilitiesWhenOpeningInterfaceFile; + (SPPreferences *)sharedPreferences; + (NSString *)titleForAutohidingBehavior:(SPAutohidingBehavior)behavior; + (NSString *)explanationForAutohidingBehavior:(SPAutohidingBehavior)behavior; @end Records show Matthew Whitaker continued promoting company accused of a 'scam' He was a company advisory board member before becoming acting attorney general. The now-shuttered World Patent Marketing Inc. once touted Matthew Whitaker’s legal chops and experience fighting fraud as a former U.S. Attorney when he was a member of the company’s advisory board. Whitaker’s connection to the company, which the Federal Trade Commission alleged was involved in “a scam that has bilked thousands of consumers out of millions of dollars, ” came under scrutiny last month after he was tapped to serve as acting attorney general, but newly released documents shed fresh light on the extent of Whitaker’s knowledge of the FTC’s fraud complaint. Despite receiving multiple fraud complaints from customers, Whitaker, during his tenure with the company, allegedly continued to promote the company’s projects, according to FTC agency records recently released as the result of a Freedom of Information request by the Washington Post. Ultimately, the FTC investigated, shut down and sued the company. The FTC’s lawsuit concluded in a settlement, in which World Patent Marketing, Inc. neither admitted nor denied the allegations, but the defendants were banned from invention-promotion related activities. The settlement also mandated that the defendants pay nearly $25 million in fines, but the FTC ultimately accepted less than $1 million. The agency did not accuse Whitaker of any wrongdoing during the lawsuit, but now some lawmakers have raised concerns about whether the acting attorney general possesses the ethics necessary for his new role. Whitaker's attorney during the case did not respond to ABC News' request for comment. ABC News was unable to reach the former CEO of the now-defunct World Patent Marketing Inc, Scott Cooper. The Department of Justice declined to comment for this report. Whitaker sat on the board of World Patent Marketing, Inc., a Florida-based invention marketing company from 2014 until 2017, when a federal court in Miami temporarily halted the company’s operations and froze its assets. Last year, in filings in the Southern Florida district court, the FTC alleged that the company lured in customers by publishing fraudulent “success stories,” failed to deliver on promises, and took drastic measures to suppress negative reviews. According to records released by the agency on Friday, Whitaker from 2014 to 2016, received phone calls, voicemails, emails from dissatisfied World Patent Marketing consumers, as well an in-person visit as his Iowa office from one client. An email Oct. 24, 2017 from a FTC investigator included in the filings says that Whitaker told the FTC that he forwarded complaints to Cooper, and that he never emailed or wrote to consumers. However, previously records made public by the FTC as part of its lawsuit reveal that Whitaker did respond to a customer complaint in 2015. “I am a former United States Attorney for the Southern District of Iowa,” Whitaker wrote on Aug. 21, 2015. “Your emails and message from today seem to be an apparent attempt at possible blackmail or extortion. “You also mentioned filing a complaint with the Better Business Bureau and to smear World Patent Marketing’s reputation online,” Whitaker continued. “I am assuming you understand that there could be serious civil and criminal consequences for you.” The FTC’s initial complaint alleges that emails like this were part of a strategy the company employed to prevent upset customers from sharing their accounts. “If consumers threaten to complain about Defendants business practices, including by threatening to post complaints on the internet or complain to the Better Business Bureau or law enforcement, Defendants respond by threatening to file a lawsuit for extortion, defamation, and other causes of action,” the FTC claimed in court filings. The new documents released as a result of the Washington Post FOIA show that on numerous occasions, Cooper included Whitaker in his responses to disgruntled customers, often evoking the advisory board member’s status as a former U.S. attorney. Cooper also relied on Whitaker to build his company’s reputation. In 2014, he sent an email with the subject line “Let’s build a Wikipedia page and use Whitaker to make it credible.” The same here, he asked Whitaker if he would be interested in appearing in commercials for World Patent Marketing. “Our business is expanding so you might get some good visibility nationally,” Cooper wrote. Whitaker replied expressing his interest. While it’s unclear if commercials were ever taped, scripts and marketing emails from 2014 reveal that portraying Whitaker as reputable was a priority. “We used Matt as the spokesperson but then added a voiceover to make the offer,” a marketing executive wrote in an email to Cooper. “We don’t want Matt being a “shill” rather he should be a knowledgeable, trusting presence.” In 2017, the FTC sent Whitaker a subpoena, requiring he turn over information related to his work with World Patent Market. Whitaker did not meet the deadline, but eventually responded to investigators, telling them he had just started a new job as chief of staff to then-Attorney General Jeff Sessions, and that he wanted to be “very helpful.” But Senate Democrats have questioned Whitaker’s involvement with the company and his initial delay in responding to the FTC. “These new revelations of Mr. Whitaker’s extensive involvement in World Patent Marketing – as it was carrying out a massive scheme to defraud consumers – and his lackluster response to a federal investigation are beyond alarming,” Senator Bob Udall, D-N.M., said in a statement released Friday. “Mr. Whitaker’s involvement in such a fraudulent entity – and his apparent personal knowledge of the worst allegations – add to the growing pile of undeniable questions regarding his ability to fulfill the responsibilities of his new role as the nation’s top law enforcement official,” Udall continued. During a Tuesday hearing before a subcommittee of the Senate Commerce Committee, FTC Chairman Joseph Simons said the agency would brief lawmakers on the matter. The FTC’s lawsuit concluded in a settlement, in which World Patent Marketing, Inc. neither admitted nor denied the allegations. The defendants were banned from invention-promotion related activities. An investigation by the U.S. Postal Inspection Service and the FBI's Miami office into the company ongoing.Add the PWI Blog to Your Google Homepage Wednesday, July 27, 2011 Triple-H As New WWE Head? More Like Triple-F Just around the same time Internet chatter took off about the 2011 “PWI 500,” Triple-H assumed leadership of WWE’s day-to-day operations. We can tell you that “Trips” didn’t rank in this year’s “500,” due mainly to the amount of time he spent on the injured reserve list during the evaluation period. However, if we were to analyze and rank Triple-H for his early performance as a wrestling executive, he’d appear
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^{+0.20}_{-0.19}$\ \ FWHM &$S_0$\ kpc & photon cm$^{-2}$ s$^{-1}$ arcsec$^{-2}$\ 35.3$^{+2.9}_{-2.7}$ & 6.25$^{+0.78}_{-0.72}$ $\times$10$^{-7}$\ X-ray spectral modeling {#sec:spectral} ----------------------- In order to determine a suitable region for the extraction of photons for X-ray spectroscopy, we perform a second spatial fit to the surface-brightness distribution, this time using a single 2-D $\beta$-model. A radial surface-brightness profile is then extracted using the best-fit centre of this model as the centre position, as shown in Fig. \[fig:profile\]. From this profile, we determine the radius at which the surface-brightness profile becomes statistically indistinguishable from the blank-sky background. At $r{=}0.556$ Mpc (98.4$''$), the signal-to-noise ratio (S/N) of the global cluster emission is maximised, such that extending any measurement to larger radii would predominantly add background. ![Radial profile of the X-ray surface brightness, computed relative to the centre of a single-component $\beta$-model. The blue line shows the background predicted from appropriately scaled blank-sky observations. The vertical dotted line marks the radius at which the observed emission becomes statistically indistinguishable from the background.](profile.pdf "fig:"){width="8.5cm"}\ \ \[fig:profile\] ![X-ray spectrum, best-fit plasma model, and residuals. The spectral fitting is actually performed separately but simultaneously on the three event files. Here we overplot the three spectra, where green, red, and blue data points are from ObsID of 11719, 12300, and 13194, respectively.[]{data-label="fig:xspectrum"}](spectrum.pdf "fig:"){width="8.5cm"}\ \ Within this radius, we measure a total of 17200 net photons and 1990 background photons in the 0.5–7.0 keV band. All spectral fits are performed in [Sherpa]{} [@2001SPIE.4477...76F], using the plasma model of combined with the photoelectric absorption model of @1983ApJ...270..119M. Fits are performed simultaneously on the three datasets, using $\chi^2$ statistics. Of the five fit parameters, we freeze two, namely the cluster redshift (set to $z=0.428$), and the absorption which we fix at the Galactic value of $1.00 \times 10^{20}$ cm$^{-2}$ . Fitting for the remaining three model parameters, we find a global temperature of $9.55^{+0.58}_{-0.37}$ keV, a metal abundance of $Z{=}0.27\pm 0.06$, and an unabsorbed X-ray flux of $(4.05 \pm 0.12)\times 10^{-12}$ erg s$^{-1}$ cm$^{-2}$ in the quoted energy band. The data, best-fitting model, and residuals are shown in Fig. \[fig:xspectrum\]; the goodness of fit as quantified by $\chi^2$ per degree of freedom is 0.80. Thawing the absorption leads to a best-fit value of $(1.85^{+1.06}_{-1.04}) \times 10^{20}$ cm$^{-2}$ which is fully consistent with the Galactic value; all other best-fit values are also unchanged within their 1$\sigma$ errors. In order to explore whether multi-phase gas is present, we also perform a fit with a two-component plasma model. The resulting best-fit results are indistinguishable from the ones obtained with a single-phase model, as the best-fit amplitude of the second component is negligible. Finally, we also fit for the cluster redshift and measure $z=0.420^{+0.014}_{-0.020}$ from the redshifted 7 keV Fe line clearly visible in Fig. \[fig:xspectrum\], in excellent agreement with the value derived from optical galaxy spectroscopy. The rest-frame X-ray luminosity of the cluster within the region selected for X-ray spectroscopy is measured to be $(2.56 \pm 0.06) \times 10^{45}$ erg s$^{-1}$, $(1.67_{-0.02}^{+0.01})\times 10^{45}$ erg s$^{-1}$, $(1.90 \pm 0.07)\times 10^{45}$ erg s$^{-1}$, and $(4.04_{-0.13}^{+0.16} )\times 10^{45}$ erg s$^{-1}$ in the 0.5–7.0 keV, 0.1–2.4 keV, 2–10 keV, and bolometric passbands, respectively. The quoted uncertainties are the nominal 1$\sigma$ errors propagated from the errors of the temperature and normalisation of the spectral fit. We can extrapolate these luminosities to larger radii using the best-fit spatial model. From the X-ray temperature[^3], we estimate $r_{500}$, $r_{1000}$, and $r_{2500}$ using the formula in , $$\begin{aligned} \label{eqn:delta} R_{\Delta} &=& 3.80\beta_{T}^{1/2}\Delta_{z}^{-1/2}(1+z)^{-3/2} \\ & & \times (kT/10~\mathrm{keV})^{1/2}h_{50}^{-1} ~~\mathrm{Mpc} \nonumber \end{aligned}$$ Here $\beta$ = 1.05 is the normalisation of the virial relation, i.e., $GM/(2R_{vir})=\beta_{T}kT$, and $\Delta_z = (\Delta\Omega_{m_0})/(18\pi^2\Omega_m(z))$ with $\Delta$ being the desired overdensity. Setting $\Delta$ to 500, 1000, and 2500 yields $r_{500}{=}1.35$ Mpc (239$''$), $r_{1000}{=}0.95$ Mpc (169$''$), and $r_{2500}{=}0.60$ Mpc (107$''$). Our measurement aperture of $r{=}0.56$ Mpc (98$''$) corresponds to $\Delta \sim 2900$. Using the best model from our two-dimensional fit to the spatial data we thus find $L_X(<r_{500})$ of $2.69 \times 10^{45}$ erg s$^{-1}$, $1.76 \times 10^{45}$ erg s$^{-1}$, $2.00 \times 10^{45}$ erg s$^{-1}$, and $4.24 \times 10^{45}$ erg s$^{-1}$ for the for 0.5–7.0 keV, 0.1–2.4 keV, 2–10 keV and bolometric passbands, respectively. Gas mass and total mass ----------------------- The normalisation factor of the spectral fit and the best-fit spatial model allow us to estimate the total X-ray gas mass within a given region. The normalisation of the [mekal]{} model is given by $${\tt norm}={10^{-14}\over4 \pi {D_A}^2(1+z)^2}\int n_e n_H dV \label{eq:norm}$$ where the emission measure, $\int n_e n_H dV$, can be written as $${\tt EM} = (n_H/n_e) \int n_e(\vec{r})^2 dV,$$ and the gas mass is given by $$M_{gas} = \mu' m_p (n_H/n_e) \int n_e(\vec{r})^2 dV.$$ Here $m_p$ is the proton mass, $\mu'$ = 1.347, and $n_H/n_e$ = 0.852 for an ionized plasma with a metallicity of 0.3 of the solar value . ![Profiles of 3D and 2D gas mass derived for oblate and prolate geometries. For each set of curves, the upper one corresponds to oblate geometry. The vertical dotted line marks the radius from Fig. 3 at which our existing observations fail to detect significant emission from the cluster.[]{data-label="fig:mass"}](mass.pdf){width="8.5cm"} We deproject the surface-brightness distribution determined by the spatial model in Section \[sec:xsb\] to a three-dimensional gas density profile $$\begin{aligned} \label{eqn:beta3d} \rho(r) &=& \rho_0 \left [ \left (1+\frac{r}{r_0} \right )^2 \right ] ^{-\frac{3}{2}\beta}\\ ~ r &=& \sqrt{x^2+ \frac{y^2}{(1-\epsilon_y)^2}+ \frac{z^2}{(1-\epsilon_z)^2}} \nonumber\end{aligned}$$ where x and y are aligned with the major and minor axes of the ellipse projected on the plane of the sky, z is along our line of sight, and $\epsilon_y$, $\epsilon_z$ are the corresponding ellipticities. We can then numerically integrate the right-hand side of Eqn. \[eq:norm\] to obtain the central density $\rho_0$ (and $n_{e0}$) of each of the three spatial components
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746, 1532, 36, 938, 50263, 18, 15, 31699, 575, 9, 25, 10, 187, 50276, 36, 21, 1532, 36, 22, 50264, 18, 15, 34458, 575, 9, 25, 10, 50273, 36, 938, 1532, 41, 938, 34, 50264, 17, 15, 4185, 361, 187, 50276, 36, 22, 1532, 41, 22, 34, 50265, 17, 15, 4185, 361, 50270, 36, 938, 1532, 41, 938, 35, 50264, 17, 15, 4185, 361, 187, 50276, 36, 22, 1532, 41, 22, 35, 50265, 17, 15, 4185, 361, 50270, 36, 938, 1532, 41, 938, 36, 50264, 17, 15, 4185, 361, 187, 50276, 36, 22, 1532, 41, 22, 36, 50265, 17, 15, 4185, 361, 50270, 2019, 1532, 48, 23, 50261, 18, 15, 25569, 575, 9, 22, 10, 187, 50276, 36, 23, 1532, 41, 23, 34, 50265, 17, 15, 4185, 361, 50270, 2019, 1532, 48, 20, 50261, 18, 15, 30977, 575, 9, 21, 10, 187, 50276, 36, 23, 1532, 41, 23, 35, 50265, 17, 15, 4185, 361, 50270, 2019, 1532, 48, 21, 50261, 18, 15, 28418, 575, 9, 22, 10, 187, 50276, 36, 23, 1532, 41, 23, 36, 50265, 17, 15, 4185, 361, 50270, 2019, 1532, 48, 22, 50261, 18, 15, 29579, 575, 9, 22, 10, 187, 50276, 36, 24, 1532, 36, 25, 50264, 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1166, 10, 50275, 36, 25, 1532, 36, 26, 1532, 41, 26, 35, 50267, 12852, 15, 22, 187, 50276, 48, 18, 1532, 30785, 1532, 47, 21, 50269, 1525, 15, 3680, 575, 9, 1036, 10, 50274, 41, 26, 34, 1532, 36, 26, 1532, 41, 26, 35, 50268, 12852, 15, 22, 187, 50276, 47, 20, 1532, 30785, 1532, 47, 21, 50269, 3507, 15, 1976, 575, 9, 1036, 10, 50274, 36, 25, 1532, 36, 26, 1532, 41, 26, 36, 50267, 12852, 15, 22, 187, 50276, 47, 18, 1532, 30785, 1532, 47, 21, 50269, 4739, 15, 1508, 575, 9, 1036, 10, 50274, 41, 26, 34, 1532, 36, 26, 1532, 41, 26, 36, 50268, 12852, 15, 22, 187, 50276, 48, 18, 1532, 30785, 1532, 47, 19, 50269, 2511, 15, 3583, 575, 9, 1036, 10, 50274, 41, 26, 35, 1532, 36, 26, 1532, 41, 26, 36, 50268, 12852, 15, 22, 187, 50276, 47, 20, 1532, 30785, 1532, 47, 19, 50269, 4529, 15, 2904, 575, 9, 1166, 10, 50274, 47, 20, 1532, 36, 740, 1532, 36, 883, 50268, 14322, 15, 17, 575, 9, 21, 10, 187, 50276, 47, 18, 1532, 30785, 1532, 47, 19, 50269, 3245, 15, 2950, 575, 9, 1166, 10, 50274, 47, 20, 1532, 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-------------- -------------- Geometric parameters (Å, °) {#tablewrapgeomlong} =========================== -------------------- ------------- ----------------------- ------------ Zn---O1 1.973 (4) C9---H9A 0.9800 Zn---N1 2.124 (4) C9---H9B 0.9800 Zn---N2 2.216 (4) C9---H9C 0.9800 Zn---N3 2.095 (4) C10---C11 1.521 (7) Zn---N4 2.153 (4) C10---C12 1.534 (7) O1---C19 1.286 (6) C10---H10 1.0000 O2---C19 1.261 (7) C11---H11A 0.9800 N1---C1 1.504 (6) C11---H11B 0.9800 N1---C17 1.508 (6) C11---H11C 0.9800 N1---H1N 0.882 (10) C12---H12A 0.9900 N2---C3 1.473 (7) C12---H12B 0.9900 N2---C4 1.500 (7) C13---C14 1.518 (8) N2---H2N 0.878 (10) C13---C16 1.537 (7) N3---C8 1.497 (7) C13---C15 1.535 (8) N3---C10 1.499 (6) C14---H14A 0.9800 N3---H3N 0.879 (10) C14---H14B 0.9800 N4---C12 1.478 (7) C14---H14C 0.9800 N4---C13 1.511 (7) C15---H15A 0.9800 N4---H4N 0.880 (10) C15---H15B 0.9800 C1---C2 1.518 (7) C15---H15C 0.9800 C1---C3 1.523 (8) C16---C17 1.537 (7) C1---H1 1.0000 C16---H16A 0.9900 C2---H2A 0.9800 C16---H16B 0.9900 C2---H2B 0.9800 C17---C18 1.524 (7) C2---H2C 0.9800 C17---H17 1.0000 C3---H3A 0.9900 C18---H18A 0.9800 C3---H3B 0.9900 C18---H18B 0.9800 C4---C6 1.528 (9) C18---H18C 0.9800 C4---C7 1.537 (8) C19---C20 1.476 (8) C4---C5 1.540 (8) C20---H20A 0.9800 C5---H5A 0.9800 C20---H20B 0.9800 C5---H5B 0.9800 C20---H20C 0.9800 C5---H5C 0.9800 Cl---O6 1.420 (5) C6---H6A 0.9800 Cl---O3 1.415 (4) C6---H6B 0.9800 Cl---O4 1.422 (5) C6---H6C 0.9800 Cl---O5 1.484 (5) C7---C8 1.559 (8) Cl1---O15 1.405 (7) C7---H7A 0.9900 Cl1---O16 1.435 (7) C7---H7B 0.9900 Cl1---O13 1.415 (4) C8---C9 1.497 (8) Cl1---O14 1.474 (8) C8---H8 1.0000 O1---Zn---N3 128.04 (17) C7---C8---H8 105.8 O1---Zn---N1 121.79 (16) C8---C9---H9A 109.5 N3---Zn---N1 109.96 (17) C8---C9---H9B 109.5 O1---Zn---N4 99.58 (16) H9A---C9---H9B 109.5 N3---Zn---N4 82.75 (16) C8---C9---H9C 109.5 N1---Zn---N4 91.23 (16) H9A---C9---H9C 109.5 O1---Zn---N2 89.52 (16) H9B---C9---H9C 109.5 N3---Zn---N2 92.08 (17) N3---C10---C11 113.0 (4) N1---Zn---N2 83.46 (17) N3---C10---C12 107.5 (4) N4---Zn---N2 170.89 (16) C11---C10---C12 109.9 (4) C19---O1---Zn 124.3 (4) N3---C10---H10 108.7 C1---N1---C17 114.5 (4) C11---C10---H10 108.7 C1---N1---Zn 105.6 (3) C12---C10---H10 108.7 C17---N1---Zn 120.6 (3) C10---C11---H11A 109.5 C1---N1---H1N 109 (4) C10---C11---H11B 109.5 C17---N1---H1N 104 (4) H11A---C11---H11B 109.5 Zn---N1---H1N 102 (4) C10---C11---H11C 109.5 C3---N2---C4 117.2 (4) H11A---C11---H11C 109.5 C3---N2---Zn 103.2 (3) H11B---C11---H11C 109.5 C4---N2---Zn 119.4 (3) N4---C12---C10 109.3 (4) C3---N2---H2N 103 (4) N4---C12---H12A 109.8 C4---N2---H2N 102 (4) C10---C12---H12A 109.8 Zn---N2---H2N 111 (4) N4---C12---H12B 109.8 C8---N3---C10 113.7 (4) C10---C12---H12B 109.8 C8---N3---Zn 117.3 (3) H12A---C12---H12B 108.3 C10---N3---Zn 109.0 (3) N4---C13---C14 106.6 (4) C8---N3---H3N 110 (4) N4---C13---C16 110.4 (4) C10---N3---H3N 103 (4) C14---C13---C16 111.8 (5) Zn---N3---H3N 102 (4) N4---C13---C15 110.7 (4) C12---
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want to take this exercise a step further, I challenge you to write your own definitions for “highest services, right living, and true ends of education”. In addition, what is Brother Morrison saying in this quote? Take a few minutes and think about these words on the screen, and the fact they are on a screen and not on an actual page… These are just a few examples of thoughts and questions you can ask yourself and your members if you seek to decipher the words on the page. The fact of the matter is that our members will only understand our Ritual to the degree that they comprehend the meanings of the words on the page. Now, by understand, I’m not referring to having a notion, idea, or feeling, but rather a level of comprehension that one can apply, voice, and model that understanding to others. This is not to say that every member should dedicate years to vigilant study and attaining meaning from the words of Ritual. It simply means that we should work together in helping each other to learn about the words on the page. It means that through sacrificing a little time and deriving greater truth and purpose from the words on the page, we will have the essential ability to articulate what it means to live out those principles and be the men and women we swore to be. Brother Luke Benfield is the Director of Education at General Headquarters. Luke is a member from the Georgia Gamma Chapter at Mercer University. He has a bachelor’s degree in English literature and economics, as well as a master’s degree in educational leadership. Before coming to GHQ, Luke was the Fraternity and Sorority Life Advisor at Coastal Carolina University, as well as the IFC advisor at Florida Gulf Coast University in graduate school. Happy National Ritual Celebration Week! If I had to choose the mantra of the fraternal world in vogue these days, it would have to be “Live Your Ritual,” and there is no better time than now to focus on the ideals that our fraternal rituals espouse. “Living Your Ritual” is a noble thought, but just how does one go about accomplishing this lofty goal? We know that to be successful in achieving a goal, we must have a plan. One popular example is S.M.A.R.T. – our goals must be Specific, Measurable, Achievable, Realistic, and Timely. Are they? Simply by asking our members to “Live Your Ritual” defies the very first step of achieving our goal. It is far too vague a command to know exactly what that means and when we have been successful., especially with such a moving, ongoing target. A better option is to clearly define what our individual organizations ask of our members. For some, those ideals may be expressed in a Creed; for others, the key concepts may be part of an Initiation oath or pledge. I will share the example I am most familiar with as Phi Mu’s National Ritual Chairman. Phi Mu’s Creed sets a standard for members asking them to strive to live loving, honorable, and truthful lives. We all have a certain idea of what each of these means, but the concepts are still far too vague to be measurable. What does it mean to be loving? Phi Mu’s Creed spells out the expectations: “to lend to those less fortunate a helping hand; to think of God as a protector and guide of us all; to keep forever sacred the memory of those we have loved and lost.; to be to others what we would they would be to us; to keep our lives gentle, merciful and just.” And to be honorable? By “guarding the purity of our thoughts and deeds; being steadfast in every duty small or large, believing that our given word is binding; striving to esteem the inner man above culture, wealth or pedigree; being honorable, courteous, tender.” And finally, our members are expected “to serve in the light of truth, avoiding egotism, narrowness and scorn; to give freely of our sympathies.” I have yet to meet many individuals who can live up to these lofty standards 100% of the time. I will freely admit that I haven’t, but I also know that I try. Some may think it silly of me to keep a copy of the Phi Mu Creed on the dresser where I get ready in the mornings, but it serves to remind me of the kind of person I want to be. We are human beings with human flaws and these are, after all, high expectations. So have I failed? Have we failed? Have our members failed us, or have we failed them? The Rituals of our fraternal organizations provide a framework for and a picture of the kind of lives we want for our members. We fail our members by not being specific about our expectations. Too often, we recruit our members based on one set of standards and expectations (appearance, partying opportunities), then we do a “bait and switch” when it comes to expecting them to live according to our Ritual. The two are not always in sync. We fail our members, too, when we do not give them the support and motivation to live our Ritual. Are we providing opportunities for philanthropic work if that is one of our goals? Are we holding memorial services for loved ones we have lost? Are we being the sister/brother to them that we expect them to be to us? When a member strays from our expectations, are we quick to judge and punish, or do we provide a system to address the unacceptable behavior and provide support for change? Do we recognize those that are living examples of our expectations? To make our Ritual goals more tangible and to demonstrate their achievability, we should be allowing time at every meeting for members who have exemplified our ideals to be recognized and applauded. Our efforts at clearly defining the meaning of “Living Our Ritual” pay off when we see a measurable difference in the number and caliber of members we recruit and in the number of “cases” that must come before our disciplinary boards. Along the way we may find that for some “Living our Ritual” is not realistic. Is that a bad thing? After all, shouldn’t our members have a shared vision of what it means to be a member? Where do we begin such a monumental task as “Living Our Ritual”? Let us clearly define what that means and challenge each and every member to invest in our ideals. Let’s take inventory annually to evaluate our shortcomings and plan for change if needed. Let’s celebrate success! If we truly want to change the too-often negative image of Greek life, let’s not only let our Rituals and ideals be known, but let’s “shout it from the mountaintop” that we are organizations truly striving to develop responsible members to lead their families, their communities and the world today and tomorrow. And we are succeeding! Let’s not make that a well-kept secret! Peggy King was initiated into the Alpha Eta Chapter of Phi Mu Fraternity at Louisiana State University in 1969. She has served as Phi Mu’s National Council Member-at-large, National Alumnae Vice-president, Volunteer Coordinator, Phi Mu Foundation Trustee and as National Ritual Chairman since 2002. She has received the Fraternity’s Outstanding Alumnae Achievement Award as well as LSU’s Greek Excellence Award and a Leave a Legacy Award in her local community. Peggy holds a B.S. in Spanish, an M.A. in Cultural Anthropology and an MA+30 in Curriculum and Instruction. She currently teaches Spanish in LSU’s Osher Lifelong Learning Institute and is an assessment administrator for Westat, a research company under contract to the U.S. Department of Education. As Phi Delta Theta helps observe National Ritual Celebration Week I was asked to share some thoughts on what it means to “Live The Ritual.” I realize that, from time to time, I am asked by university administrators, parents, alumni, and undergraduate members to give a definitive definition of how I know when a chapter is “living the ritual” of Phi Delta Theta. And when I think about this question I’ve come to the conclusion that I know when a chapter is living the ritual when a mom tells me it’s so. Now, I’m going to come back to this “mom as judge” concept a little bit later, but let me first share some thoughts on being a Fraternity man – with a capital ‘F.” It would be easy and completely appropriate for me to define ‘living the ritual’ as achieving the highest grades on campus; providing a tremendous amount of community service hours and raising a lot of money for charity; holding a lot of campus leadership positions; and using the ritual in all chapter meetings and functions. And while each of these specific acts are visible, public and measurable – and all are good activities that I certainly encourage – for me they don’t define this idea of ‘living the ritual.’ As I think about the three cardinal principles of Friendship, Sound Learning and Rectitude laid out by our Founders 164 years ago in The Bond of Phi Delta Theta, and supported in the ritualistic ceremonies that are the backbone of our Fraternity, they describe to me the characteristics of my concept of a Fraternity man. I want to return for a minute to the original view and perception of Fraternity men by the broader society. I have always been struck by a visual representation of a Fraternity man which
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important factors in the initiation of Alzheimer's disease (AD) pathogenesis and influence the formation of neurotoxic β-amyloid (Aβ) peptides. An important risk factor, the presence of ApoE4 protein in AD brain cells binds the lipids to AD. In addition, lipid signaling pathways have a crucial role in the cellular homeostasis and depend on specific protein-lipid interactions. The current review focuses on pathological alterations of membrane lipids (cholesterol, glycerophospholipids, sphingolipids) and lipid metabolism in AD and provides insight in the current understanding of biological membranes, their lipid structures and functions, as well as their role as potential therapeutic targets. Novel methods for studying the membrane structure and lipid composition will be reviewed in a broad sense whereas the use of lipid biomarkers for early diagnosis of AD will be shortly summarized. Interactions of Aβ peptides with the cell membrane and different subcellular organelles are reviewed. Next, the details of the most important lipid signaling pathways, including the role of the plasma membrane as stress sensor and its therapeutic applications are given. 4-hydroxy-2-nonenal may play a special role in the initiation of the pathogenesis of AD and thus the "calpain-cathepsin hypothesis" of AD is highlighted. Finally, the most important lipid dietary factors and their possible use and efficacy in the prevention of AD are discussed.<?php use jianyan\basics\backend\widgets\menu\AddonLeftWidget; if(Yii::$app->params['addon']['info']['type'] != 'plug') { $this->params['breadcrumbs'][] = ['label' => '扩展模块','url' => ['index']]; } $this->params['breadcrumbs'][] = ['label' => $addonModel['title'],'url' => ['binding','addon' => $addon]]; ?> <div class="col-sm-2" style="width: 15%; height: 100%;background:#fff;"> <?= AddonLeftWidget::widget(); ?> </div> <div class="col-sm-10" style="width: 85%;padding-left: 0;padding-right: 0;"> <?= $this->render($view,$params); ?> </div>Earlier this year it looked like Alex Tettey’s time at Norwich City was coming to an end – but instead the midfield lynchpin is on the verge of passing a major milestone. If Tettey keeps his place for Saturday’s game at Blackburn it will be a 200th Canaries appearance for the 32-year-old, who is now in his seventh season with the club. The former Norway international’s next match in City colours will move him clear of John Deehan into 70th place in the all-time appearances list, one short of Ken Foggo and Les Eyre on 201. He’ll also be in reach of the likes of Darren Huckerby (203), Darren Eadie (203) and Neil Adams, in 60th place on 206. So should Tettey remain a first-choice regular under Daniel Farke this season, he should have a decent shot at overtaking Ruel Fox, in 56th on 219. The tough tackling Canaries favourite could even have a shot of reaching the top 50, having signed a two-year contract during the final week of last season, to take his stay through to 2020. Alex Tettey scored on his Norwich City debut, in a League Cup clash with Doncaster at Carrow Road Picture: Paul Chesterton/Focus Images To make that top 50 the Ghana-born battler will have to surpass the 232 appearances achieved by World Cup winner Martin Peters and Scottish defender Malky Mackay – and to do that Tettey will have to continue as a regular under Farke. When the German took over as head coach in the summer of 2017, bringing higher technical demands of midfielders, it looked like the former Rennes and Rosenberg man was set for a role as a fringe player during the final year of his contract. After spending the first four league games of Farke’s reign on the bench, Tettey emerged to play a key role in starting an eight-game unbeaten run in the Championship, bringing balance to an off-kilter team. However, a calf injury kept the physical competitor out for two months and by the time he was fit again, form had nosedived and the transitional first season under Farke and sporting director Stuart Webber was teetering on a cliff edge. Wembley glory was one of Alex Tettey's top achievements as a Norwich player Picture: Paul Chesterton/Focus Images The fan favourite returned at Birmingham on Boxing Day and provided pivotal ballast once again in a 2-0 win. City lost just one of 12 league games with Tettey back on the front line. He even started wearing the captain’s armband regularly during the second half of last season, with Ivo Pinto falling out of favour, as his revival continued amid regular speculation about his future. A return to Rosenborg and a reunion with Alex Neil at Preston were among the rumours as it looked like Tettey would be on his way in the summer. All the attention was on Wes Hoolahan as the Irishman said farewell during an emotional 2-1 win over Leeds in the final home game of the last campaign, but what about Tettey? Alex Tettey scored the winning goal as Norwich won away to Manchester United in the Premier League in December 2015 Picture: Paul Chesterton/Focus Images The midfielder missed that game with a back strain, leaving uncertainty, until the situation was turned on its head when news broke that City had offered a new two-year contract, albeit on significantly reduced wages. In turn the man who once fired the Canaries to a rare Old Trafford victory, just before Christmas three years ago, has become a crucial part of Farke’s team becoming the surprise package of this season’s Championship promotion race. He has started 20 of 22 league matches and completed all but two of those. There have been a few wobbly moments, bouncing back from a sloppy display against Preston in August by thumping home a late goal to make sure of a 2-0 home win. He also endured a shaky afternoon during the 2-2 draw at Bristol City on Saturday, narrowly avoiding a second yellow card and losing the ball in the lead up to the hosts’ first goal. But in the main Tettey has proved as valuable to Farke as he has to his previous Norwich managers – so I wouldn’t bet against him reaching that all-time top 50 just yet. NCFC APPEARANCES • 65= Alan Black – 203 65= Thomas Halliday – 203 65= Darren Huckerby – 203 65= Mick McGuire – 203 • 69= Les Eyre – 201 69= Ken Foggo – 201 • 71= ALEX TETTEY – 199 71= John Deehan – 199 • 73 Geoff Butler – 196 • 74 Jimmy Hill – 195 • 75 Mike Phelan – 194 If you value what this story gives you, please consider supporting the Eastern Daily Press. Click the link in the yellow box below for details. This newspaper has been a central part of community life for many years, through good times and bad, serving as your advocate and trusted source of local information. Our industry is facing testing times, which is why I’m asking for your support. Every single contribution will help us continue to produce award-winning local journalism that makes a measurable difference to our community.Q: Store for-loop iterations in memory I'm writting a simple bash script to do a recursive paste over >10000 files with two columns each. The files looks like this: A1BG 3 A1CF 3 A2M 3 A4GALT 5 AAAS 2 AACS 2 AADAT 2 AAGAB 4 AAK1 3 AAMP 2 AANAT 3 AARS 2 AARS2 3 AARSD1 2 ... And the code is this: SPHERE=Sphere.matrix.txt rm -rf $SPHERE for i in `ls *.spheres | sort`; do if [ -f $SPHERE ]; then cut -f2 $i \ | paste $SPHERE - > $SPHERE.tmp mv $SPHERE.tmp $SPHERE else cat $i > $SPHERE fi done it opens the first file and writes it to the output file. then it opens the second file, it takes the second colums and it pastes it to the output file, and so on... the code works propperly, but it gets progresively slower because in each cycle it has to open and overwrite a bigger file. if I could store the result of aech iteration in memory instead of in disk, I think that the performnace would be much faster. could you please give me some guidance in this? thank you so much! A: If I understood right, and all files have the same number of rows, you can use gnu awk to take col 2 of each file except the first, one line at
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är det som håller på att hända? All mat renas I Bibeln får man äta all slags mat. Det finns inget förbud. Det är nog inget problem för klimatet heller vad för slags mat vi äter, utan det är nog andra problem. Förresten så renar kroppen all mat, vilket Jesus själv säger. Mark 7:18. Då sa han [Jesus] till dem: Är ni också så oförståndiga? Förstår ni inte att inget som utifrån kommer in i människan kan orena henne? 19. För det går inte in i hennes hjärta utan ner i magen, genom vilken all mat renas och har sin naturliga utgång. En sak är viktigt Dessutom står det också så här i Bibeln: Apg 15:28. För den Helige Ande och vi har beslutat att inte lägga på er någon ytterligare börda, förutom detta som är nödvändigt: 29. Att ni ska avhålla er från det som är offrat åt avgudarna, och från blod, och från kött av kvävda djur och från otukt. Om ni noga aktar er för detta, gör ni rätt. Farväl. Själv resonerar jag så här om vad som är nyttigt och onyttigt: Ät allt i lagom mängd så blir det nog inga problem. Vilken tröst detta ger oss. Vi behöver inte hålla på med massa lagar och kontroll för att bli frälsta. Bara en enda sak är viktigt och det är att man tar emot Jesus och blir frälst. Jag läste en gång om en läkare som drack två liter morotsjuice om dagen eftersom det skulle vara nyttigt. Han dog av skrumplever för att hans lever klarade inte av så mycket morotsjuice varje dag. Propaganda Det här med klimatet verka vara en undanflykt för att kontrollera människor. Vad är det för en agenda som egentligen ligger bakom? Är det för att till sist kunna sätta Antikrist på tronen? Du behöver inte vara rädd för vad du äter, och inte heller behöver du ha dåligt samvete. Ät och må bra. Gå inte på propagandan som kommer på olika sätt för att kunna styra och kontrollera ditt liv. Sådan propaganda blir mer och mer tydligt i den tid som vi nu lever i. Det är ett tidstecken. Det enda som är viktigast och betydelsefullt i ditt liv är att du tar emot Jesus Kristus och blir frälst! Rom 14:17. För Guds rike är inte mat och dryck, utan rättfärdighet och frid och glädje i den Helige Ande. Christer Åberg #Vegeterian #Adolf Hitler #Förskola #Västerbotten #Klimatet 24 kommentarer Sida 1 av 3 Sida 2 av 3 Sida 3 av 3 1 2 »3 VIP: molecular biology and neurobiological function. In the mammalian brain, a major regulatory peptide is vasoactive intestinal peptide (VIP). This 28 amino acid peptide, originally isolated from the porcine duodenum, was later found in the central and peripheral nervous systems and in endocrine cells, where it exhibits neurotransmitter and hormonal roles. Increasing evidence points to VIP's importance as a mediator or a modulator of several basic functions. Thus, VIP is a major factor in brain activity, neuroendocrine functions, cardiac activity, respiration, digestion, and sexual potency. In view of this peptide's importance, the mechanisms controlling its production and the pathways regulating its functions have been reviewed. VIP is a member of a peptide family, including peptides such as glucagon, secretin, and growth hormone releasing hormone. These peptides may have evolved by exon duplication coupled with gene duplication. The human VIP gene contains seven exons, each encoding a distinct functional domain on the protein precursor or the mRNA. VIP gene transcripts are mainly found in neurons or neuron-related cells. VIP gene expression is regulated by neuronal and endocrine signals that contribute to its developmental control. VIP exerts its function via receptor-mediated systems, activating signal transduction pathways, including cAMP. It can act as a neurotransmitter, neuromodulator, and a secretagog. As a growth and developmental regulator, VIP may have a crucial effect as a neuronal survival factor. We shall proceed from the gene to its multiple functions.import re from telethon import TelegramClient def test_all_methods_present(docs_dir): with (docs_dir / 'quick-references/client-reference.rst').open(encoding='utf-8') as fd: present_methods = set(map(str.lstrip, re.findall(r'^ {4}\w+$', fd.read(), re.MULTILINE))) assert len(present_methods) > 0 for name in dir(TelegramClient): attr = getattr(TelegramClient, name) if callable(attr) and not name.startswith('_'): assert name in present_methods #include "peerlistmodel.hpp" #include <fmt/format.h> #include <libtorrent/peer_info.hpp> #include "../../core//utils.hpp" namespace lt = libtorrent; using pt::UI::Models::PeerListModel; PeerListModel::PeerListModel() { } PeerListModel::~PeerListModel() { } void PeerListModel::ResetPeers() { m_data.clear(); Reset(0); } void PeerListModel::Update(std::vector<lt::peer_info> const& peers) { // Remove old data for (auto it = m_data.begin(); it != m_data.end();) { auto f = std::find_if( peers.begin(), peers.end(), [it](lt::peer_info const& p) { return p.ip == it->ip; }); if (f == peers.end()) { it = m_data.erase(it); RowDeleted(std::distance(m_data.begin(), it)); } else { ++it; } } // Add or update new data for (auto it = peers.begin(); it != peers.end(); it++) { auto f = std::find_if(m_data.begin(), m_data.end(), [it](lt::peer_info& p) { return p.ip == it->ip; }); if (f == m_data.end()) { m_data.push_back(*it); RowAppended(); } else { auto distance = std::distance(m_data.begin(), f); m_data.at(distance) = *it; RowChanged(distance); } } } unsigned int PeerListModel::GetColumnCount() const { return Column::_Max; } wxString PeerListModel::GetColumnType(unsigned int col) const { return "string"; } void PeerListModel::GetValueByRow(wxVariant &variant, unsigned int row, unsigned int col) const { lt::peer_info const& peer = m_data.at(row); switch (col) { case Column::IP: variant = peer.ip.address().to_string(); break; case Column::Client: variant = wxString::FromUTF8(peer.client); break; case Column::Flags: { std::stringstream flags; if (peer.flags & lt::peer_info::interesting) { if (peer.flags & lt::peer_info::remote_choked) { flags << "d "; } else { flags << "D "; } } if (peer.flags & lt::peer_info::remote_interested) { if (peer.flags & lt::peer_info::choked) { flags << "u "; } else { flags << "U "; } } if (peer.flags & lt::peer_
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, but exactly who she wasn’t sure. The smart and ambitious teenager growing up in the Jim Crow South may not have imagined what the future held in store for her; may not have imagined that one day she would be state director of the NAACP. In Struggle Against Jim Crow: Lulu B. White and the NAACP, 1900-1957 by Merline Pitre examines the life of this civil rights champion, beginning with her birth in Elmo, Texas, in 1900, her marriage to Houston businessman and activist Julius White and her graduation from Prairie View College. On Monday, June 2, at 7:30 p.m., Texas PBS will present an online discussion with Pitre, giving readers the chance to learn more about this chapter of our state’s history. To participate, go to texasourtexas.texaspbs.org/book-club. Lulu White’s struggles to secure rights for African American citizens included politics and voting, labor, education, social and economic reforms, and gender equality. After serving as director of NAACP’s youth council and opening chapters around the state, White became president of the Houston chapter in 1939 and state director of the NAACP in 1949. The week before her death in 1957, the national NAACP established the Lulu White Freedom Fund in her honor. More discussions are coming up later this year for the Texas PBS Book Club. Here are some of the works that will be featured:Texas Women on the Cattle Trails, edited by Sara R. Massey; and Seat of Empire: The Embattled Birth of Austin,Texas by Jeffrey Kerr. The January 2014 discussion focused on America's War: Talking about the Civil War and Emancipation on Their 150th Anniversaries, edited by Edward L. Ayers. That program was made possible in part with a grant from Humanities Texas, the state affiliate of the National Endowment for the Humanities. The Texas PBS Online Book Club was formed by Texans who want more opportunities to learn and discuss our shared history. The book club meets online throughout the year and gives readers a chance to discuss topics with noted experts. Past topics have included Governor Ann Richards, the role of Texas in the Civil War and the 1937 New London, Texas, school explosion.Show Summary This is episode #441, and my guests today are partners Felipe Boss and Jesus Toledo. Most real estate investors, myself included, are guilty of focusing on the easy route as it comes to lead generation and acquisitions. Mass approaches to marketing such as direct mail are alive and well, but not performing as well as they used to. Felipe and Jesus are part of what I’ll call the new era of investors that are willing to spend more time on researching data, really understanding the specifics of their market, and ultimately, picking up the phone to contact potential sellers in a rifle vs. shotgun approach. If you’re just getting started in investing and have a limited budget, this is good news for you. If you’re a veteran investor that’s been willing to spend big money on lead generation, this is also good for you…as you have the resources to get this done. There are lots of great nuggets shared today on the show…no matter where you’re at in your real estate investing career…you’re going to learn some powerful tips. Let’s get started. Please help me welcome Felipe and Jesus to the show. Highlights of this show Meet Felipe Boss and Jesus Toledo, Investors in the Miami market. Learn the power of focusing on data to drive your lead generation activities for motivated sellers, vs. mass marketing approaches. Join our conversation about the importance of knowing your market, zoning issues, and trends at the zip code level better than anyone else. Learn about the importance of getting comfortable with using the phone as your #1 tool with sellers. Resources and Links from this show: Listen to the Audio Version of this Episode FlipNerd Show Transcript: Mike: This is the FlipNerd.com Expert Real Estate Investing Show, the show for real estate investors, whether you’re a veteran or brand new. I’m your host, Mike Hambright, and each week, I bring you a new expert guest that will share their knowledge and lessons with you. If you’re excited about real estate investing, believe in personal responsibility and taking control of your life and financial destiny, you’re in the right place. This is episode number 441, and my guests today are partners Felipe Boss and Jesus Toledo. Most real estate investors, myself included, are guilty of focusing on the easy route as it comes to lead generation and acquisitions. Mass approaches to marketing, such as direct mail, are alive and well, but they’re just not performing as well as they used to. Felipe and Jesus are a part of what I’ll call the new era of investors that are willing to spend more time on researching data, really understanding the specifics of their market, and ultimately willing to pick up the phone and contact potential sellers in a rifle versus a shotgun approach. If you’re just getting started in investing and have a limited budget, this is good news for you. Now if you’re a veteran investor that’s been willing to spend big money on lead generation, this is also good for you as you have the resources to get this done unlike anyone else. There are a lot of great nuggets shared in today’s show. I don’t want to steal the thunder here. No matter where you’re at in your real estate investing career, you’re going to learn some very powerful tips and some useful information that you can put in place right now to help build your business. Let’s go ahead and get started. Please help me welcome Felipe and Jesus to the show. Hey, guys. Welcome to the show. Felipe:Thank you. Jesus:Thank you, Mike. Thank you for having us. Mike:Yeah, excited to have you. Jesus:It’s a pleasure. Mike:Yeah, excited to have you guys on today. And honestly it’s fairly rare. We’ve had it before. We had two people on at once, but you guys are like brothers. You’re tied at the hip and mad scientists over there, so I’m really excited to have you on. I’m really excited to talk today about, you know, we were talking about this ahead of time for folks that are listening right now is, and I’m guilty of this too. As a real estate investor for the past 10, 11 years, I’ve kind of done what most investors do, and that’s kind of the shotgun approach, like as I grow I just write a bigger and bigger check and send out more and more direct mail or try to do things in a mass way that is easy for me to push a button from behind a computer and not kind of get laser focused. But, you know, a lot of those things that we’ve done over the years just aren’t working as well as they used to, and people that are doing really well right now, like you guys, I found are taking a very kind of systematic and more of a rifle approach versus a shotgun approach. So I don’t want to steal all of your thunder, but that’s kind of the premise of what we’re going to talk about today. So again, excited to have you guys here. Hey, before we get started, why don’t you guys tell us a little bit about your background and kind of how you got started in real estate investing. Felipe: I mean, our background where, we’ve been friends for about 20 years. Born and raised in South America in Chile. And we both moved to Miami, what was it? I moved here 10 years ago. Jesus: And I moved six years ago, yeah. Mike: Okay. Jesus: Since I was in college I started some businesses in Chile, some online-related businesses, and when I moved into the U.S., I was looking to do something differently. And then after a few years going back and forth, I finally convinced Felipe. Felipe: He dragged me to a real estate investing club here in Broward. That’s how it all started. Mike: Going to a real estate club. Jesus: Yeah. We read the “Rich Dad Poor Dad,” and they were mentioning the national REIA association. And then we started looking for one nearby, and we ended up going to one and I convinced Felipe, “Let’s go, please trust me. This one is going to be good. Let’s go. Let’s go.” And we went to it and we decided to go all in. Mike: That’s great. You know what’s funny, on the show like literally, probably a third of the shows I’ve ever had usually say, you know, “Then I read ‘Rich Dad Poor Dad'” or “Then I went to a real estate club,” and so it’s kind of a cliché at this point, but that’s how most people . . . Honestly, I was the same way. I went to a real estate, a local real estate club and, you know, I didn’t learn a whole lot there, but that was the catalyst that got me interested and kind of hooked. Jesus: No, it was absolutely the same for us. Of course, we learned from them, we connected with a lot of people, but we didn’t take the mentoring program there or anything.
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optical elements. A propagating light wave of constant phase is divided into two wavefronts that are directed along separate optical paths, namely, a test path and a reference path. The test path includes the optical surface being tested, and the reference path includes a known reference surface. After reflecting from test and reference surfaces, the two wavefronts are recombined forming an interferogram. Fringe patterns of the interferogram are interpreted to obtain measures of the surface topography of the test surface. A majority of precision optical surfaces are spherical segments. The known interferometric techniques are especially well suited to measure concave spherical surfaces. For example, a point light source may be located in the test path at the center of curvature of the concave test surface. To the extent that the test surface is truly spherical, the light impinges at normal incidence to the test surface and is retroreflected along its original path back to the light source. Any deviation of the reflected light from its original path produces fringe distortions in an interference pattern with a reference wavefront indicative of a departure from sphericity. However, it is much more difficult to use interferometric techniques to measure large convex spherical surfaces. Additional optical elements are used to relay an image of the point source to the center of curvature of convex surfaces. The point source image is relayed by lenses that must be made large enough to produce a converging light beam having marginal rays at normal incidence to the periphery of the convex surface. These lenses are expensive and difficult to make to required accuracy. In fact, it becomes impractical to manufacture optical elements with sufficient accuracy for measuring certain large aperture convex surfaces with the known interferometric techniques.Double-balloon endoscopy: an effective rescue procedure after incomplete conventional colonoscopy. A significant percentage of colonoscopies remain incomplete because of a failure to intubate the caecum. By double-balloon endoscopy (DBE), originally developed for deep enteroscopy, an otherwise incomplete examination of the colon might be completed. We evaluated the success rate of caecal intubation, the reasons for its failure and the therapeutic consequences of using DBE after incomplete conventional colonoscopy. We report our single-centre experience of using DBE to complete an otherwise incomplete colonoscopy. A total of 114 consecutive patients, 45 male and 69 female, with a mean age of 64.8 years, who had undergone 116 procedures, were evaluated retrospectively by a review of their medical records. The main causes for failed caecal intubation using a conventional colonoscope were loop formation in 70 patients (61.4%) and an adhesive angulated sigmoid in 33 (28.9%). Caecal intubation by DBE was successful in 101 patients (88.6%). The rate of failure was not associated with the cause of failure of the previous colonoscopy. In 55 patients (48.2%) a relevant new diagnosis was made in the previously inaccessible part of the colon: carcinoma (n=4; 3.5%), one or more adenomas (n=48; 42.1%) and caecal flat hyperplastic polyps (n=4; 3.5%). Endoscopic polypectomy was performed in 51 patients (44.7%); two complications occurred, both being mild postpolypectomy bleedings. In seven patients (6.1%) a subsequent surgical resection was performed. Colonoscopy by DBE was useful in most patients in whom conventional colonoscopy was incomplete, irrespective of the cause of the failure. In nearly half the patients, a relevant new diagnosis was made with therapeutic consequences.India Pale Ales, or IPAs, of course, have long been an obsession in craft beer, and Holtzman admits that Yuengling's IPL comes around as a result of "the popularity of the IPA style." And with Yuengling having long mastered the lager style with their flagship Traditional Lager brew, the move seems like a natural progression.Pictured above: Jacques d'Amboise in George Balanchine's Apollo, 1963. D'Amboise was acclaimed by critics as "the definitive Apollo" for his interpretation of this 1928 ballet. In his autobiography, I Was a Dancer, d'Amboise writes that he saw his own journey reflected in this signature role, described by its choreographer as depicting how "a wild, untamed youth learns nobility through art." (Photograph by John Dominis.) Pictured left: Cover design for He Makes Me Feel Like Dancin', a 1983 Academy Award-winning documentary about Jacques d'Amboise by Emile Ardolino. The documentary includes footage of d'Amboise teaching schoolchildren through the National Dance Institute, which he founded to bring dance and arts education to public schools. Jacques d’Amboise has single-handedly done much to broaden appreciation for ballet in America. As a principal dancer with New York City Ballet he shattered stereotypes by creating a masculine, all-American image for ballet, and since retiring from the stage he has brought dance education to countless public school children. Born Joseph Jacques Ahearn on July 28, 1934 in Dedham, Massachussetts, he grew up in Washington Heights, New York City, and entered the School of American Ballet at the age of eight. At just fifteen he joined New York City Ballet, becoming one of the first dancers to graduate from the school into the company. George Balanchine created a wide variety of roles for him, and he was especially celebrated for his interpretation of Balanchine’s 1928 ballet Apollo. He was known for his exuberance, athleticism, skilled partnering, and on-stage joie-de-vivre, qualities that were also on view in films like Seven Brides for Seven Brothers (1954). In 1976, d’Amboise founded the National Dance Institute, which brings arts education and appreciation into public schools. His work with the Institute has taken him around the world, and he has also promoted dance through films, television programs, and books. He has been widely recognized and honored for both his artistic excellence and his humanitarian work. www.nationaldance.org Pictured left: Jacques d'Amboise in Ballet Encounter, a program organized by d'Amboise in the 1970s that presented compilations of ballet excerpts with a touring company including fellow NYCB dancers. D'Amboise has long been committed to expanding the audience for ballet. (Ann Barzel Dance Research Collection, The Newberry Library, Chicago.) Pictured right: Jacques d'Amboise in George Balanchine's Stars and Stripes. Set to Sousa marches, this ballet captured the quality of all-American exuberance and athleticism that Balanchine found in his adopted country and in Jacques d'Amboise, who became the choreographer's protégé after joining New York City Ballet at the age of 15. (Photograph by Gjon Mili.)IHT have interviewed Pharrell Williams and Camile Miceli about their new jewellery line for Louis Vuitton, the interview answers many of the questions people have been asking, how the project came about, what inspired the name, and much much more./* * Copyright 2002-2019 the original author or authors. * * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * https://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. */ package org.springframework.ui; import java.util.Collection; import java.util.Map; import org.springframework.lang.Nullable; /** * Java-5-specific interface that defines a holder for model attributes. * Primarily designed for adding attributes to the model. * Allows for accessing the overall model as a {@code java.util.Map}. * * @author Juergen Hoeller * @since 2.5.1 */ public interface Model { /** * Add the supplied attribute under the supplied name. * @param attributeName the name of the model attribute (never {@code null}) * @param attributeValue the model attribute value (can be {@code null}) */ Model addAttribute(String attributeName, @Nullable Object attributeValue); /** * Add the supplied attribute to this {@code Map} using a * {@link org.springframework.core.Conventions#getVariableName generated name}. * <p><i>Note: Empty {@link java.util.Collection Collections} are not added to * the model when using this method because we cannot correctly determine * the true convention name. View code should check for {@code null} rather * than for empty collections as is already done by JSTL tags.</i> * @param attributeValue the model attribute value (never {@code null}) */ Model addAttribute(Object attributeValue); /** * Copy all attributes in the supplied {@code Collection} into this * {@code Map}, using attribute name generation for each element. * @see #addAttribute(Object) */ Model addAllAttributes(Collection<?> attributeValues); /** * Copy all attributes in the supplied {@code Map} into this {@code Map}. * @see #addAttribute(String, Object) */ Model addAllAttributes(Map<String, ?> attributes); /**
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as an error, the picture is not right. And if it is NOT detected, again the picture is not right. Is what I say correct? A: About the logo itself: The logo itself is like a real stack overflow in some ways and not in others. The colors going from gray to orange maybe signifies danger in the logo as you go higher in the stack, a better representation for a stack overflow though, would be to have all elements completely gray until it reached the maximum size, and then it would turn red for everything above it. The logo correctly shows that the elements of the stack are exceeding the stack limit. Usually your program will crash or you will get a segmentation fault as soon as you exceed your stack. In this way the logo is not like a real stack overflow. Because it shows many items on top of the stack. The logo properly displays that it is a stack: The logo has a container for the elements in the stack The logo shows that there are elements in the stack. The logo shows that the bottom of the stack is closed, meaning things enter it first in last out. About what a stack overflow is: A stack has a maximum address that should not be exceeded. This maximum address can be exceeded by pushing something onto the stack. The size of the stack determines what this maximum address can be. You can set this stack size for your programs. As an aside, the opposite is a stack underflow, where you try to pop from the stack when nothing is on it, resuling in going under the minimum address that cannot be exceeded. Here is an example of a stack overflow: int functionCall() { char x[102400000]; // <--- Just an example, may not overflow if stack is very large //... return 0; } Here is another example of a stack overflow, In this example the stack is exceeded because every function call pushes something on the stack: void MyRecursiveFunction() { MyRecursiveFunction(); } A: It's just a logo, and you are all crazy people. For the humour-impaired, ;), but also, come on... :|. A: What is a stack overflow? Well my friends, years ago, back in the dark ages of computing, a colleague came to me with a problem. His code was randomly crashing, and he couldn't figure out where the bug was. By crash I mean write random characters to random spots on the screen, lock up, and require physical powering down. Yes, this was the world of DOS, the IBM pc, back when we ran without virtual memory or "protected" memory segments. So it turns out my colleague was running with the default 4k stack. Yes, 4 kilobytes. Get out your magnifying glass. Back in those days, the stack started at one end of memory. Code went at another. Heap went at another. The heap and stack kind-of worked up/down toward each other. When they met, it was "troublesome". Only my colleague's compiler put his compiled binary code up at the end of the stack. And he declared a large array of floats on the stack. A very large array, for his stack size. It took up a little over 3k. Eventually, when his function call tree got deep enough, he overwrote his code. Eventually, he called that code. My friends, THAT is a stack overflow. You people today, with your virtual memory and coredumps. You have it easy! q) = 0. -1, 6 Let j(w) be the second derivative of -31/3*w**4 + 32/3*w**3 + 8*w**2 + 11/5*w**5 + 0 + 15*w. Suppose j(a) = 0. Calculate a. -2/11, 1, 2 Suppose -129*w**5 + 3*w**5 + 1060*w**2 - 170*w**5 - 980*w**4 + w**5 + 50*w**5 - 20*w + 265*w**3 - 80 = 0. Calculate w. -4, -1, -2/7, 2/7, 1 Let n be 42/21 - 9/12. Let n*t**4 - 7/4*t - 1/2 + 7/4*t**3 - 3/4*t**2 = 0. What is t? -1, -2/5, 1 Let u be -1 - (-65)/15 - 2. Let a be 1 - -1*(3 - 2). Factor 10/3*z**a - 22/3*z + u. 2*(z - 2)*(5*z - 1)/3 Suppose 4*a = 3*a + 3. Suppose -6 = a*k - 5*k. Factor -k*z**3 - z**2 - 5*z**3 + 2*z**3 - 2*z**2 - 3*z**4. -3*z**2*(z + 1)**2 Let c = -5818/87 + 1949/29. Factor 0 + c*x**2 + 2/3*x - 1/3*x**3. -x*(x - 2)*(x + 1)/3 Let v be ((-84)/(-98))/((-4)/(-14)). Factor -2*n**4 + 6*n**2 - 6*n**3 + 6*n**v + 5*n**3 + n**4. -n**2*(n - 6)*(n + 1) Let k(r) = 6*r**4 + 29*r**3 + 103*r**2 - 7*r - 7. Let p(h) = 7*h**4 + 29*h**3 + 104*h**2 - 8*h - 8. Let b(a) = -8*k(a) + 7*p(a). Find f, given that b(f) = 0. -3, 0, 32 Let c = 118 - 114. Let f(s) be the second derivative of -1/4*s**c + 0 - 24*s**2 - 2*s + 4*s**3. Factor f(d). -3*(d - 4)**2 Let u = 101/132 - 5/132. Determine i so that -8/11*i + 0 + 6/11*i**3 + u*i**2 - 2/11*i**5 - 4/11*i**4 = 0. -2, 0, 1 Let n(w) be the first derivative of -5/4*w**2 - 19 + 5/18*w**3 + 0*w. Factor n(h). 5*h*(h - 3)/6 Let c = -219 + 221. Let 0*s - 1/3*s**c - 2/3*s**3 + 0 = 0. Calculate s. -1/2, 0 Let p be 1/(-3)*1872/(-130). Determine s so that p + 4*s - 4/5*s**2 = 0. -1, 6 Let j(l) be the third derivative of 7*l**6/160 + 29*l**5/5 + 7755*l**4/32 + 1089*l**3/4 - 12*l**2. Let j(p) = 0. What is p? -33, -2/7 Let x(t) be the second derivative of 1/360*t**6 + 0 + 1/8*t**2 + 1/40*t**5 + 5/36*t**3 - 3*t + 1/12*t**4. Factor x(y). (y + 1)**3*(y + 3)/12 Let z = 19681/13 + -1513. Factor 2/13*u**4 + 8/13*u**3 + 2/13 + z*u**2 + 8/13*u. 2*(u + 1)**4/13 Let d be (18/45)/((-3)/(-15)). Factor -88*p**3 - 6*p + 91*p**3 - 3*p**d - 5*p**2 + 5*p**2. 3*p*(p - 2)*(p + 1) Let j(k) be the first derivative of 3*k**4/4 + 6*k**3 + 12*k**2 + 134. Suppose j(y) = 0. What is y? -4, -2, 0 Let a = -175 + 174. Let p(c) = 3*c**2 - 6*c**2 - 3*c**2. Let k(t) = t**3 - t**2 - t - 1. Let o(y) = a*p(y) + 3*k(y). Factor o(b). 3*(b - 1)*(b + 1)**2 Let p(c) be the first derivative of -c**6/15 - 6*c**5/5 - 37*c**4/5 - 44*c**3
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p>5$, $\omega\in\left(\tfrac4{\beta^2}\tfrac{p+1}{p-1}, \omega_1\right)$, meanwhile $e^{i\omega t}\varphi^{ass}_{\omega,\beta}$ is unstable for $p>5$, $\omega>\omega_2>\omega_1.$ The solutions in the case $\beta<0$ can be defined similarly (see Figure 3). In this case the constants $y, y_1, y_2$ have to be negative. ; ; ; ; ; ; In the second part of the paper we study the orbital stability of the standing wave solutions $$\mathbf{U}(t,x)=e^{i\omega t}\mathbf{\Phi}(x)=\left(e^{i\omega t}\varphi_j(x)\right)_{j=1}^N$$ for the NLS-$\delta$ and NLS-$\delta'$ equation on the star graph which appears to be more complicated problem. It is easily seen that amplitude $\mathbf{\Phi}\in D_\alpha$ of the standing wave of equation satisfies the following stationary equation $$\label{H_alpha} \mathbf{H}_\alpha^\delta\mathbf{\Phi}+\omega\mathbf{\Phi}-|\mathbf{\Phi}|^{p-1}\mathbf{\Phi}=0.$$ In [@AdaNoj14] the authors obtained the following description of all solutions to equation . [@AdaNoj14 Theorem 4]\[1bump\] Let $[\cdot]$ denote the integer part of the real number. Let also $\alpha<0$, and $\omega>\tfrac{\alpha^2}{(N-2k)^2}$, for some $k\in\left\{0,...,\left[\tfrac{N-1}{2}\right]\right\}$. Then equation has $k+1$ (up to permutations) vector solutions $\mathbf{\Phi}_m^\alpha=(\varphi^\alpha_{m,j})_{j=1}^N, \,\,m=0,...,k$, which are given by $$\begin{split} \varphi_{m,j}^\alpha(x)&= \left\{ \begin{array}{ll} \Big[\frac{(p+1)\omega}{2} \operatorname{sech}^2\Big(\frac{(p-1)\sqrt{\omega}}{2}x-a_m\Big)\Big]^{\frac{1}{p-1}}, & \quad\hbox{$j=1,..,m$;} \\ \Big[\frac{(p+1)\omega}{2} \operatorname{sech}^2\Big(\frac{(p-1)\sqrt{\omega}}{2}x+a_m\Big)\Big]^{\frac{1}{p-1}}, & \quad\hbox{$j=m+1,...,N,$} \end{array} \right.\\ \text{where}\;\; a_m&=\tanh^{-1}\left(\frac{\alpha}{(2m-N)\sqrt{\omega}}\right). \end{split}$$ Moreover, for $-N\sqrt{\omega}<\alpha<\alpha^*<0$, the vector solution $ \mathbf{\Phi}^\alpha_0=(\varphi_{0,j}^\alpha)_{j=1}^N$, $$\label{Phi_vect} \varphi_{0,j}^\alpha(x)=\left[\frac{(p+1)\omega}{2} \operatorname{sech}^2\left(\frac{(p-1)\sqrt{\omega}}{2}x+\tanh^{-1}\left(\frac{-\alpha}{N\sqrt{\omega}}\right)\right)\right]^{\frac{1}{p-1}}$$ is the ground state. Note that vector $\mathbf{\Phi}_m^\alpha=(\varphi^\alpha_{m,j})_{j=1}^N$ has $m$ *bumps* and $N-m$ *tails*. It is easily seen that $\mathbf{\Phi}^{\alpha}_0$ is the *N-tail profile*. Moreover, the $N$-tail profile is the only symmetric (i.e. invariant under permutations of the edges) solution of equation . In the case $N=5$ we have three types of profiles: a *5-tail profile*, a *4-tail/1-bump profile* and a *3-tail/2-bump profile*. They are demonstrated on Figure 4 (from the left to the right). (0,-3) rectangle (18,2); (2,1).. controls +(-0.7,-0.7) .. (0.3,0.2); (2,1).. controls +(-0.3,-0.9) .. (0.5,-1); (2,1).. controls +(0.2,-1) .. (2.8,-1.2); (2,1) .. controls +(0.2,-0.5) .. (4.2,-0.2); (2,1).. controls +(0.6,-0.3) .. (3.5,1); (2,0)–++(-2,0); (2,0)–++(-1.8,-1.3); (2,0)–++(1,-1.7); (2,0)–++(2.5,-0.5); (2,0)–++(2,1); (2,1).. controls +(-0.5,0.5) and +(1.5,-0.1) .. (0.3,0.2); (2,1).. controls +(-0.3,-0.9) .. (0.5,-1); (2,1).. controls +(0.2,-1) .. (2.8,-1.2); (2,1) .. controls +(0.2,-0.5) .. (4.2,-0.2); (2,1).. controls +(0.6,-0.3) .. (3.5,1); (2,0)–++(-2,0); (2,0)–++(-1.8,-1.3); (2,0)–++(1,-1.7); (2,0)–++(2.5,-0.5); (2,0)–++(2,1); ; (2,1).. controls +(-0.5,0.5) and +(1.5,-0.1) .. (0.3,0.2); (2,1).. controls +(-0.3,-0.9) .. (0.5,-1); (2,1).. controls +(0.2,-1) .. (2.8,-1.2); (2,1) .. controls +(0.2,-0.5) .. (4.2,-0.2); (2,1).. controls +(0.3,0.5) and +(-0.8,-0.5) .. (3.5,1); (2,0)–++(-2,0); (2,0)–++(-1.8,-1.3); (2,0)–++(1,-1.7); (2,0)–++(2.5,-0.5); (2,0)–++(2,1); The parameter $\alpha^*$ in Theorem \[1bump\] originates from the variational problem associated with equation and guarantees constrained minimality of the action functional $$\label{S_graph} S_\omega^\alpha(\mathbf{\Psi})=\tfrac 1{2}||\mathbf{\Psi}'||^2+\tfrac{\omega}{2}||\mathbf{\Psi}||^2 -\tfrac 1{p+1}||\mathbf{\Psi}||_{p+1}^{p+1}+\tfrac{\alpha}{2}|\psi_1(0)|^2, \quad \mathbf{\Psi}=(\psi_j)_{j=1}^N\in\mathcal E(\mathcal{G}).$$ Namely, the vector solution $\mathbf{\Phi}_0^\alpha$ is the ground state in the sense of minimality of $S_\omega^\alpha(\mathbf{\Psi})$ at $\mathbf{\Phi}_0^\alpha$ with the constraint given by the Nehari manifold $$\mathcal N=\{\mathbf{\Psi}\in \mathcal E(\mathcal{G}): ||\mathbf{\Psi}'||^2+\omega ||\mathbf{\Psi}||^2 - ||\mathbf{\Psi}||_{p+1}^{p+1}+\alpha |\psi_1(0)|^2=0\}.$$ In [@AdaNoj14] the following orbital stability result has been shown. [@AdaNoj14 Theorem 2]\[st\_graph\] Let $1<p\leq 5$,$\alpha<\alpha^*<0$, and $\omega>\tfrac{\alpha^2}{N^2}$. Then the ground state $e^{i\omega t}\mathbf{\Phi}_0^\alpha$ is orbitally stable in $\mathcal{E}(\mathcal{G})$. Stronger version of the above theorem was proved in [@AdaNoj15 Theorem 1]. In particular, the authors proved orbital stability of $e^{i\omega t}\mathbf{\Phi}_0^\alpha$ for $\alpha<0$ without restriction $\alpha<\alpha^*<0$. The proof is based on a new original technique that allows one to restrict the analysis to functions made of pieces of soliton, reducing the problem to a finite dimensional one and avoiding to use direct methods of calculus of variations and linear
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private static class ContainerException extends YarnException { public ContainerException(String message) { super(message); } @Override public YarnException getCause() { return null; } } } Q: Selecting r pairwise disjoint subsets from a set of n elements The question I have is as follows: Assume that you have an $n$–element set $U$ and that you select $r$ independent random subsets $A_1, . . . , A_r ⊂ U$. All $A_i$ are chosen so that all $2^n$ choices are equally likely. Compute (in a simple closed form) the probability that the $A_i$ are pairwise disjoint. My attempt: My first thought was to use Stirling numbers of the second kind. However, the question doesn't say that the union of all subsets should be the entire set, so that doesn't work. Next I tried to do via counting. We have to choose $r$ subsets from a total of $2^n$ subsets. For the sample space, we have that each one of the $r$ positions has $n$ choices. So, we have a total of $2^{nr}$ choices. For the numerator, I attempted this: From the $2^n$ subsets, choose one. This can be done in $2^n \choose 1$ way, and then the second in $2^n-1 \choose 1$ and so on till we select $r$ subsets. However, I realised that not all of the subsets in this will be pairwise disjoint and I'll be over-counting.(we can select {1,2} in the first choice, {2,3} in the second choice). So, I am stuck here. I do have the solution, which gives the solution in terms of choosing a $r \times n$ matrix with $0$ or $1$ filled independently with probability $1/2$ and which has at most one $1$ in every column, which I am unable to understand. Can someone help? A: You want to count the $r$-tuples of subsets $(A_1,\ldots,A_r)$ of $U$ with the $A_i$ disjoint. Think of these $A_i$ as boxes in which you can throw the elements of $U$. Let $u\in U$. Then you can throw $u$ into one of the $A_i$, or keep it and not throw it into any of the boxes. So you have $r+1$ options for $u$. As $U$ has $n$ elements, you have $(r+1)^n$ options overall. /** * Hero */ %toc-expanded { max-height: none; overflow: visible; .expand { display: none; } } .home .lander-header { padding: 2 * $spacing-unit 0; @include media-query($on-palm) { padding: $spacing-unit 0; } & .columns { display: flex; align-items: center; @include media-query($on-palm) { display: block; .col1 { text-align: center; } .col2 { display: none; } } .col1 { margin-top: -10px; flex: 1 1 55%; } .col2 { flex: 1 1 45%; // Bug in Safari // Need to keep the search dropdown from being overlapped // https://stackoverflow.com/a/18167565/3369702 -webkit-transform: translateZ(-1px); } } .site-description { margin: 0; padding: 0; line-height: 1.35; max-width: 560px; font-size: 54px; color: $text-color; font-family: $base-font-family; @include media-query($on-palm) { font-size: 32px; } } .site-description-full { margin: $spacing-unit / 2 0 0; line-height: 1.6; font-size: 20px; color: $secondary-text-color; font-family: $base-font-family; a { font-weight: 700; color: $secondary-text-color; } @include media-query($on-palm) { margin-top: 5px; font-size: 18px; } } .controls { margin-top: $spacing-unit; @include media-query($on-palm) { margin-top: 20px; } a.button { padding: 19px 28px; text-transform: uppercase; font-family: $base-font-family; display: inline-block; font-size: 14px; font-weight: 700; letter-spacing: 1px; @include media-query($on-palm) { margin-left: auto; margin-right: auto; display: block; max-width: 250px; } &:first-child { margin-right: $spacing-unit / 2; background-color: darken($brand-color, 25%); @include media-query($on-palm) { margin-right: auto; margin-bottom: 10px; } } &:first-child:hover { background-color: darken($brand-color, 15%); } &:last-child { background-color: $important-color; } &:last-child:hover { background-color: lighten($important-color, 5%); } } } .certificate { $title-color: #65647D; $border-color: #C2873F; margin: 0 auto; width: 350px; height: 450px; padding: 10px; box-sizing: border-box; border-radius: 2px; background-color: #FDFDFB; position: relative; transform-style: preserve-3d; box-shadow: 0 15px 35px rgba(0, 0, 0, 0.1), 0 5px 15px rgba(0, 0, 0, 0.07); .wreath { $size: 200px; position: absolute; top: 60%; left: 50%; opacity: 0.025; margin-top: - $size / 2; margin-left: - $size / 2; width: $size; height: $size; background: transparent url(/assets/lander/laurel-wreath.svg) no-repeat center; background-size: $size auto; } .border { box-sizing: border-box; height: 100%; border: 4px solid $border-color; } .title { text-transform: uppercase; text-align: center; letter-spacing: 1px; font-size: 14px; padding-top: $spacing-unit; color: lighten($title-color, 10%); } .separator { margin: $spacing-unit - 5px 80px; border-top: 2px solid $border-color; } ul { list-style: none; margin-left: 22px; li { margin-top: 62px; font-size: 18px; color: $secondary-text-color; span { $size: 24px; width: $size; height: $size; line-height: $size; margin-right: 6px; vertical-align: -1px; display: inline-block; border-radius: $size / 2; background-color: lighten($title-color, 10%); text-align: center; i.fa { font-size: 12px; vertical-align: 2px; &.fa-pencil { vertical-align: 3px; } } } } } .wreath { transform: translateZ(10px); }
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, like in Juvenile Idiopathic Arthritis (JIA) or Systemic Lupus Erythematosus (SLE). Aim of present study was to evaluate whether the clinical score LoSCAT can be helpful for clinicians with low experience in scoring and in management of JLS in assessment and monitoring of patients. Furthermore, we compared mLoSSI with IRT, a reliable non-invasive tool with limited availability in pediatric rheumatology centers \[[@CR5]\]. Comparison of IRT with LoSDI was not considered since lesions with severe atrophy and fat loss appear falsely positive on IRT \[[@CR5]\]. In previous studies, LoSCAT was found to be reliable and sensitive to change and indeed, distinguishing the aspects of activity and tissue damage, allowed physicians to monitor these two conditions separately \[[@CR15], [@CR16]\]. One important result of our study is that mLoSSI showed excellent inter-observer agreement (ICC = 0.965) independent from physician's experience, thus confirming results of previous studies \[[@CR13]\]. Indeed, we showed that the site of the lesions did not affect mLoSSI reliability which was very good also in areas like neck, face, hands and feet, difficult to evaluate and demonstrated that no specific training in scoring or in JLS assessment is necessary to use this clinical tool effectively. In monitoring over time, we observed that mLoSSI was reliable in picking up changes in disease activity, as inter-observer concordance was excellent. Furthermore, mLoSSI variations were consistent with an advanced technology such as IRT therefore confirming that this simple clinical tool can be helpful for monitoring activity in any outpatient setting. The LoSDI damage evaluation showed more heterogeneous results as ICC was very good (ICC 0.774) but variance analysis indicated low concordance between examiners. In fact, although a similar trend between scores of examiners was observed, they differed in several points. This may be partially explained by the small number of lesions in some body areas and by difficulty in performing clear-cut distinction between degrees of DAT and SAT, probably influenced by clinician's experience and absence of an appropriate training. The small variations observed in LoSDI scores over an average of 4 months' time are quite expectable as it evaluates relatively stable cutaneous features. LoSCAT do not include the evaluation of extracutaneous manifestations, such as bone deformities, joint contractures, central nervous system involvement etc. and has some limitations also in detecting changes in deeper layers. Dermal and subcutaneous fat thickness as well as fascia, muscle and bone involvement can be successfully evaluated by high-frequency Doppler ultrasound, MRI and, on face, by CBCT \[[@CR9]--[@CR13]\]. These tools, combined with clinical assessment, may help in more precise definition and monitoring of tissue damage. Nevertheless, we demonstrated that LoSCAT, based on simple clinical evaluation, showed good reliability in evaluating active lesions over time, in fact different clinical experience in JLS did not influence clinical judgement in active lesions, while in damage assessment LoSDI was less precise and not completely reliable in monitoring skin changes. IRT confirmed to be a helpful tool for detecting disease activity and reliable in monitoring lesions over time. ANOVA : Analysis of Variance CSS : Computerized Skin Score DAT : Dermal atrophy DP : Depigmentation ER : Erythema ICC : Intraclass Correlation Coefficient IRT : Infrared Thermography JLS : Juvenile Localized Scleroderma LoSCAT : Localized Scleroderma Cutaneous Assessment Tool LoSDI : Localized Scleroderma Skin Damage Index mLoSSI : Modified Localized Scleroderma Skin Activity Index MMF : Mycophenolate Mofetil MTX : Methotrexate N/E : New/Enlarged lesion PDN : Prednisone S.D. : Standard Deviation SAT : Subcutaneous atrophy ST : Skin thickness Please contact author for data request. GF contributed to patients' assessment and draft revision, FZ contributed to design of the study and draft revision, FV made statistical analysis, AA contributed to patients' assessment and wrote the manuscript and GM contributed to design of the study, patients' assessment and revised the manuscript. All authors read and approved the final manuscript. Ethics approval and consent to participate {#FPar1} ========================================== No ethics approval was needed since LoSCAT and thermography are currently in use in the routine assessment of children with Localized Scleroderma. All participants gave their informed consent to participate. Consent for publication {#FPar2} ======================= Obtained. Competing interests {#FPar3} =================== The authors declare that they have no competing interests. Publisher's Note {#FPar4} ================ Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. On my way North I stopped in at Deep Creek, a hot spring I had been meaning to check out for a long time. Unfortunately due to battery trouble I didn’t manage to get any good pictures of it, but there’s plentyonline. I came to the Springs via Bowen Ranch, and camped there so I could stumble back to the van and pass out without driving anywhere (a must to properly enjoy any hot spring). It’s about a two mile hike down to the water from there, but it’s a nice hike. At the springs I saw a weathered old nudist and a local guy who was camping out down there (shhh) since he lost his job. He told me about how a flash flood had recently some through and filled in a lot of the pools, but he was working to clean them out. They were some very nice pools indeed. It’s probably one of the nicest natural hot springs I’ve been to. Recommended to anyone in the area. The next day I had planned to roll up to Death Valley and possibly climb Telescope Peak. However, the van was particularly finicky that day, not shifting into drive for a while. This meant I spent most of the day in town getting the van looked at so, hopefully, I wouldn’t break down in the desert. Some time on the phone that day also altered my trip plans a bit, finding out that my folks would not be in Sedona that weekend, and my friends who I was going to go to Vegas with had canceled their trip. So more than a weeks worth of my plans were shaved off! I wanted to get back to Bozeman anyway and gear up for winter, so this was fine. My trip would still be a month long by the time it was over. Sketched about the van and excited to head home I cut Death Valley out of the trip and made for Flagstaff instead, hoping to climbing Arizona’s high point Mount Humphrey. On the way to Flagstaff I did find time to turn off the Interstate and jaunt into Mojave National Preserve for a bit though. And boy am I glad I did. I hit up the 600ft tall Kelso Dunes - the third tallest dunes in North America. I got there just before sunset, and had the whole place to myself. It was a spectacular, almost spiritual experience, the kind of thing that happens to me in the outdoors frequently but never gets old and keeps me coming back again and again. The main dune was huge, and I enjoyed a hard run to the top then I just hung out, jumping down the dune and climbing back up or just sitting and watching the ridiculously brilliant sunset for over an hour. I took about a trillion photos and cursed my crappy camera for it’s epic failure at capturing the true grandeur of the scene. :) Here - despite their shortcomings - for your viewing pleasure are some of my favorite photos from the dunes.Life As A Beat Maker The Decision to Make Beats A lot of times I am asked what got me into the business of making beats, especially hip hop beats and rap beats. The answer is usually one that I really don't know, because my orignal goals with music didn't start off with the goal of becoming a beat maker. Back when I first started teaching myself to play the piano at age 11, I had one main goal in mind, and that was to create my own jazz instrumental CD and get it played on WNUA 95.5, a smooth jazz radio station in Chicago IL. I grew up listening to jazz because my father played it all the time in the car. He had always wanted to play the piano growing up, but never learned. That desire carried on in me, and one day I just woke up with a burning desire to learn. So after saving up money from my allowance and begging my parents to help me, I got my first (real) full-sized keyboard for $20. To make a long story short, I met some people and ended up being a part of a band in the attic. We would sit around all day on saturdays and record on my friend's father's 8 track tape deck. The desire grew, and eventually I decided that I wanted to have my own studio where I could record my solo instrumental jazz projects when I wasn't with the band. After enough years of saving and buying equipment piece by piece, I acquired enough equipment to record my songs to CD. I
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containing proteins are typically involved in the assembly of supramolecular complexes that perform localized signaling functions at particular subcellular locations. Organization around a PDZ-based scaffold allows the stable localization of interacting proteins and enhances the rate and fidelity of signal transduction within the complex. Some PDZ-containing proteins are more dynamically regulated in distribution and may also be involved in the trafficking of interacting proteins within the cell.3 Geometry, compatibility and structure preservation in computational differential equationshttp://sms.cam.ac.uk/collection/3028099 Computations of differential equations are a fundamental activity in applied mathematics. While historically the main quest was to derive all-purpose algorithms such as finite difference, finite volume and finite element methods for space discretization, Runge–Kutta and linear multistep methods for time integration, in the last 25 years the focus has shifted to special classes of differential equations and purpose-built algorithms that are tailored to preserve special features of each class. This has given rise to the new fields of geometric numerical integration and of structure preserving discretization. In addition to being quantitatively accurate, these novel methods have the advantage of also being qualitatively accurate as they inherit the key structural properties of their continuum counterparts. This has meant a large-scale introduction of geometric and topological thinking into modern numerical mathematics. During this scientific programme at the Isaac Newton Institute for Mathematical Sciences, we will address fundamental questions in the field of structure preserving discretizations of differential equations on manifolds in space and time. We will bring together two communities that have been pursuing their science along parallel tracks to endeavour breakthroughs in some major scientific applications, which call for advanced numerical simulation techniques. This will lead to the development of a new generation of space-time discretizations for evolutionary equations. During the programme we intend to organise three workshops and two focused study periods lasting two weeks on selected application areas. The core themes of the programme are: Compatible discretizations. Geometric numerical integration. Structure preservation and numerical relativity. Applications to computations in quantum mechanics.14402019Mon, 16 Dec 2019 16:06:02 +0000Wed, 17 Jul 2019 14:42:03 [email protected] Geometry, compatibility and structure preservation in computational differential equationshttp://sms.cam.ac.uk/collection/3028099 http://rss.sms.cam.ac.uk/itunes-image/3103513.jpghttp://video.search.yahoo.com/mrss Geometry, compatibility and structure preservation in computational differential equationsComputations of differential equations are a fundamental activity in applied mathematics. While historically the main quest was to derive all-purpose algorithms such as finite difference, finite volume and finite element methods for space discretization, Runge–Kutta and linear multistep methods for time integration, in the last 25 years the focus has shifted to special classes of differential equations and purpose-built algorithms that are tailored to preserve special features of each class. This has given rise to the new fields of geometric numerical integration and of structure preserving discretization. In addition to being quantitatively accurate, these novel methods have the advantage of also being qualitatively accurate as they inherit the key structural properties of their continuum counterparts. This has meant a large-scale introduction of geometric and topological thinking into modern numerical mathematics. During this scientific programme at the Isaac Newton Institute for Mathematical Sciences, we will address fundamental questions in the field of structure preserving discretizations of differential equations on manifolds in space and time. We will bring together two communities that have been pursuing their science along parallel tracks to endeavour breakthroughs in some major scientific applications, which call for advanced numerical simulation techniques. This will lead to the development of a new generation of space-time discretizations for evolutionary equations. During the programme we intend to organise three workshops and two focused study periods lasting two weeks on selected application areas. The core themes of the programme are: Compatible discretizations. Geometric numerical integration. Structure preservation and numerical relativity. Applications to computations in quantum mechanics. Geometry, compatibility and structure preservation in computational differential equationsComputations of differential equations are a fundamental activity in applied mathematics. While historically the main quest was to derive all-purpose algorithms such as finite difference, finite volume and finite element methods for space discretization, Runge–Kutta and linear multistep methods for time integration, in the last 25 years the focus has shifted to special classes of differential equations and purpose-built algorithms that are tailored to preserve special features of each class. This has given rise to the new fields of geometric numerical integration and of structure preserving discretization. In addition to being quantitatively accurate, these novel methods have the advantage of also being qualitatively accurate as they inherit the key structural properties of their continuum counterparts. This has meant a large-scale introduction of geometric and topological thinking into modern numerical mathematics. During this scientific programme at the Isaac Newton Institute for Mathematical Sciences, we will address fundamental questions in the field of structure preserving discretizations of differential equations on manifolds in space and time. We will bring together two communities that have been pursuing their science along parallel tracks to endeavour breakthroughs in some major scientific applications, which call for advanced numerical simulation techniques. This will lead to the development of a new generation of space-time discretizations for evolutionary equations. During the programme we intend to organise three workshops and two focused study periods lasting two weeks on selected application areas. The core themes of the programme are: Compatible discretizations. Geometric numerical integration. Structure preservation and numerical relativity. Applications to computations in quantum mechanics.Cambridge UniversityK. Kherhttp://sms.cam.ac.uk/collection/3028099 Geometry, compatibility and structure preservation in computational differential equations2019-07-17T14:42:03+01:00INIMS002281no Computational Challenges in Numerical Relativityucs_sms_3028099_3071216http://sms.cam.ac.uk/media/3071216 Computational Challenges in Numerical RelativityPretorius, F Monday 30th September 2019 - 16:00 to 17:00Mon, 30 Sep 2019 17:27:46 +0100Isaac Newton InstitutePretorius, Fcd2a54f778099decb614302c2e7a2db2979bc9c3b936f6e90f9f1d3bdc806104de29727e12e3378a157efb5ecea058bc545608e63f66795b0fde8351466994c3Pretorius, F Monday 30th September 2019 - 16:00 to 17:00Pretorius, F Monday 30th September 2019 - 16:00 to 17:00Cambridge University3840http://sms.cam.ac.uk/media/3071216 Computational Challenges in Numerical RelativityPretorius, F Monday 30th September 2019 - 16:00 to 17:00I will give a brief overview of the some of the challenges in computational solution of the Einstein field equations.I will then describe the background error subtraction technique, designed to allow for more computationally efficient solution of scenarios where a significant portion of the domain is close to a know, exact solution. To demonstrate, I will discuss application to tidal disruption of a star by a supermassive black hole, and studies of black hole superradiance.2019-09-30T17:27:46+01:0038403071216true16x9falseno Equivariance and structure preservation in numerical methods; some cases and viewpointsucs_sms_3028099_3124317http://sms.cam.ac.uk/media/3124317 Equivariance and structure preservation in numerical methods; some cases and viewpointsOwren, B Wednesday 11th December 2019 - 15:05 to 15:50Mon, 16 Dec 2019 16:06:02 +0000Isaac Newton InstituteOwren, Bc564e0df6f840a57617334f3473e4ab5908282ec48dd5793ea9f18cb7867f7c8dc77af6dc36fc473f1ec77e7c6e556366e536cec195204157e95c30f0bf0261fOwren, B Wednesday 11th December 2019 - 15:05 to 15:50Owren, B Wednesday 11th December 2019 - 15:05 to 15:50Cambridge University3178http://sms.cam.ac.uk/media/3124317 Equivariance and structure preservation in numerical methods; some cases and viewpointsOwren, B Wednesday 11th December 2019 - 15:05 to 15:50Our point of departure is the situation when there is a group of transformations acting both on our problem space and on the space in which our computations are produced. Equivariance happens when the map from the problem space to the computation space, i.e. our numerical method, commutes with the group action. This is a rather general and vague definition, but we shall make it precise and consider a few concrete examples in the talk. In some cases, the equivariance property is natural, in other cases it is something that we want to impose in the numerical method in order to obtain computational schemes with certain desired structure preserving qualities. Many of the examples we present will be related to the numerical solution of differential equations and we may also present some recent examples from artificial neural networks and discrete integrable systems. This is work in progress and it summarises some of the ideas the speaker has been discussing with other participants this autumn.2019-12-16T16:06:02+00:0031783124317true16x9falseno General Relativity: One Block at a Timeucs_sms_302
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the most important verses in the whole Gospel of John—at least for my heart. “You cannot believe in Jesus if you your root desire is to be praised by other people.” Pride at its core is the craving for human approval. And Jesus is saying that if pride is at the root, faith can’t be at the root. Faith at its core is humble gladness in the God of grace. It’s not driven by the need to deserve human praise. It is driven by a thankful joy that God is for us when we deserve no praise at all. “We have seen his glory, glory as of the only Son from the Father, full of grace and truth. . . . And from his fullness we have all received, grace upon grace” (John 1:14, 16). That is what the brothers of Jesus did not see and did not have. They had not yet been born again. The root of their joy was the praise of man, not the grace of God. That’s what John meant in verse 5 when he said that Jesus’ brothers did not believe in him. The Unbelief of the Crowds Which brings us now in closing, and very briefly, to the unbelief of the Jewish crowds. Is the root of their unbelief the same? I think it is. Both have self-exaltation at the bottom of their joy. This is what gives them satisfaction. The brothers of Jesus pursued it through his miracle-working. The Jewish crowds pursued it through law-keeping. The brothers boasted in the miracles of their brother. The crowds boasted in their keeping the law of God. In both cases, the root of joy, the root of significance, is the praiseworthy self, not the God of grace. Look at the end of verse 23: “. . . are you angry with me because on the Sabbath I made a man’s whole body well?” Yes they were. Angry enough to want him dead. Why? Jesus gives the answer in verse 19: “Has not Moses given you the law? Yet none of you keeps the law.” The Crumbling of Law-Keeping They claim to know the law, and they accuse Jesus of being a law-breaker for healing on the Sabbath. But Jesus says, “None of you keeps the law.” Jesus’ life and words are calling their whole understanding of law-keeping into question. Their whole meaning in life. Their way of finding acceptance and affirmation and approval and praise. It was all crumbling under the weight of grace and truth (John 1:17). “If you had known what this means, ‘I desire mercy, and not sacrifice,’ you would not have condemned the guiltless” (Matthew 12:7). The root of their unbelief is the same as Jesus’ brothers’ unbelief. For the brothers, the miracles of Jesus can get them human praise. For the crowds, the miracles of Jesus threaten their human praise. Written over both like a great indictment are the words of John 5:44: “How can you believe, when you receive glory from one another and do not seek the glory that comes from the only God?” Humble Gladness in the God of Grace Therefore, how should we pray for ourselves and for those we love? We should pray that, when we read of Jesus in the Gospels, or hear about him, that we would be able to say with John from the heart: “We have seen his glory, glory as of the only Son from the Father, full of grace and truth. . . . And from his fullness we have all received, grace upon grace” (John 1:14–16). Because pride, at its core, is the rejection of grace and the craving for human approval. And faith, at its core, is despairing of human approval and being glad in the God of grace. John Piper (@JohnPiper) is founder and teacher of desiringGod.org and chancellor of Bethlehem College & Seminary. For 33 years, he served as pastor of Bethlehem Baptist Church, Minneapolis, Minnesota. He is author of more than 50 books. Share the Joy! You are permitted and encouraged to reproduce and distribute this material in physical form, in its entirety or in unaltered excerpts, as long as you do not charge a fee. For posting online, please use only unaltered excerpts (not the content in its entirety) and provide a hyperlink to this page. For videos, please embed from the original source. Any exceptions to the above must be approved by Desiring God.Q: How to get objects to react to touches in Cocos2D? Alright, so I'm starting to learn more about Coco2D, but I'm kinda frusterated. A lot of the tutorials I have found are for outdated versions of the code, so when I look through and see how they do certain things, I can't translate it into my own program, because a lot has changed. With that being said, I am working in the latest version of Coco2d, version 0.99. What I want to do is create a sprite on the screen (Done) and then when I touch that sprite, I can have "something" happen. For now, let's just make an alert go off. Now, I got this code working with the help of a friend. Here is the header file: // When you import this file, you import all the cocos2d classes #import "cocos2d.h" // HelloWorld Layer @interface HelloWorld : CCLayer { CGRect spRect; } // returns a Scene that contains the HelloWorld as the only child +(id) scene; @end And here is the implementation file: // // cocos2d Hello World example // http://www.cocos2d-iphone.org // // Import the interfaces #import "HelloWorldScene.h" #import "CustomCCNode.h" // HelloWorld implementation @implementation HelloWorld +(id) scene { // 'scene' is an autorelease object. CCScene *scene = [CCScene node]; // 'layer' is an autorelease object. HelloWorld *layer = [HelloWorld node]; // add layer as a child to scene [scene addChild: layer]; // return the scene return scene; } // on "init" you need to initialize your instance -(id) init { // always call "super" init // Apple recommends to re-assign "self" with the "super" return value if( (self=[super init] )) { // create and initialize a Label CCLabel* label = [CCLabel labelWithString:@"Hello World" fontName:@"Times New Roman" fontSize:64]; // ask director the the window size CGSize size = [[CCDirector sharedDirector] winSize]; // position the label on the center of the screen label.position = ccp( size.width /2 , size.height/2 ); // add the label as a child to this Layer [self addChild: label]; CCSprite *sp = [CCSprite spriteWithFile:@"test2.png"]; sp.position = ccp(300,200); [self addChild:sp]; float w = [sp contentSize].width; float h = [sp contentSize].height; CGPoint aPoint = CGPointMake([sp position].x - (w/2), [sp position].y - (h/2)); spRect = CGRectMake(aPoint.x, aPoint.y, w, h); CCSprite *sprite2 = [CCSprite spriteWithFile:@"test3.png"]; sprite2.position = ccp(100,100); [self addChild:sprite2]; //[self registerWithTouchDispatcher]; self.isTouchEnabled = YES; } return self; } // on "dealloc" you need to release all your retained objects - (void) dealloc { // in case you have something to dealloc, do it in this method // in this particular example nothing needs to be released. // cocos2d will automatically release all the children (Label) // don't forget to call "super dealloc" [super dealloc]; } - (void)ccTouchesEnded:(NSSet *)touches withEvent:(UIEvent *)event { UITouch *touch = [touches anyObject]; //CGPoint location = [[CCDirector sharedDirector] convertCoordinate:[touch locationInView:touch.view]]; CGPoint location = [touch locationInView:[touch view]]; location = [[CCDirector sharedDirector] convertToGL:location]; if (CGRectContainsPoint(spRect, location)) { UIAlertView *alert = [[UIAlertView alloc] initWithTitle:@"Win" message:@"testing" delegate:nil cancelButtonTitle:@"okay" otherButtonTitles:nil]; [alert show]; [alert release]; NSLog(@"TOUCHES"); } NSLog(@"Touch got"); } However, this only works for 1 object, the sprite
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187, 187, 8, 8639 ]
, I suppose. Well, I'll be slipping on then. So long.' 'You were saying about that first time you met him.' 'Was I? Oh well, yes.' He laughed again. 'I mean you couldn't believe _anything_. My first day: Mickie Crabbe took me down there. We done the rounds by then. "Here," says Mickie, "just one more port of call," and takes me downstairs to see Leo. "This is Cork," he says. "Just joined us in Cyphers." So then Leo moves in.' Cork sat down on the swivel chair beside the door and leaned back like the rich executive he longed to be. ' "Glass of sherry," he says. We're supposed to be dry here, but that never bothered Leo; not that he drank himself, mind. "We must celebrate the new arrival. You don't _sing_ by any chance, do you, Cork?" "Only in the bath," I says and we all have a nice laugh. Recruiting for the choir, see: that always impressed them. Very pious gentleman, Mr Harting, I thought. Not half. "Have a cigar, Cork?" No thanks. "A fag then?" Don't mind if I do, Mr Harting. So then we sit there like a lot of dips, sipping our sherry, and I'm thinking, "Well, I must say you're quite the little king around here." Furniture, maps, carpet . . . all the trappings. Fred Anger cleared a lot of it out, mind, before he left. Nicked, half of it was. _Liberated_ , you know. Like in the old Occupation days. "So how are things in London, Cork?" he asks. "Everything much the same I suppose?" Putting me at my ease, cheeky sod. "That old porter at the main door: still saucy with the visiting Ambassadors, is he, Cork?" He really came it. "And the coal fires: still lighting the coal fires every morning, are they, Cork?" "Well," I says, "they're not doing too bad, but it's like everything else, it takes its time." Some crap like that. "Oh, ah, really," he says, "because I had a letter from Ewan Waldebere only a few months back telling me they were putting in the central heating. And that old bloke who used to pray on the steps of Number Ten, still there is he, Cork, morning and night, saying his prayers? Doesn't seem to have done us much good, does he?" I tell you: I was practically calling him sir. Ewan Waldebere was Head of Western Department by then, all set to be God. So then he comes on about the choir again and the Dutchman and a few other things besides, anything he can do to help, and when we get outside I look at Mickie Crabbe and Mickie's _pissing_ himself. Doubled up, Mickie is. "Leo?" he says. "Leo? He's never been inside the Foreign Office in his life. He hasn't even been back to England since forty-five." ' Cork broke off, shaking his head. 'Still,' he repeated, with an affectionate laugh, 'you can't blame him, can you?' He got up. 'And I mean, we all saw through him, but we still fell for it, didn't we? I mean Arthur and . . . I mean everybody. It's like my villa,' he added simply, 'I know I'll never get there, but I believe in it all the same. I mean you have to really . . . you couldn't live, not without illusions. Not here.' Taking his hands out of his mackintosh pockets, Turner stared first at Cork and then at the gunmetal key in his big palm, and he seemed to be torn and undecided. 'What's Mickie Crabbe's number?' Cork watched with apprehension as he lifted the receiver, dialled and began talking. 'They don't _expect_ you to go on looking for him,' Cork said anxiously. 'I don't really think they do.' 'I'm not bloody well looking for him, I'm having lunch with Crabbe and I'm catching the evening flight and nothing on God's earth would keep me in this dream box for an hour longer than I need.' He slammed down the receiver and stalked out of the room. * * * De Lisle's door was wide open but his desk was empty. He wrote a note: 'Called in to say goodbye. Goodbye. Alan Turner,' and his hand was shaking with anger and humiliation. In the lobby, small groups were sauntering into the sunlight to eat their sandwiches or lunch in the canteen. The Ambassador's Rolls-Royce stood at the door; the escort of police outriders waited patiently. Gaunt was whispering to Meadowes at the front desk and he fell suddenly quiet as Turner approached. 'Here,' he said, handing him the envelope. 'Here's your ticket.' His expression said, 'Now go back to where you belong.' 'Ready when you are, old son,' Crabbe whispered from his habitual patch of darkness. 'You see.' * * * The waiters were quiet and awfully discreet. Crabbe had asked for snails which he said were very good. The framed print in their little alcove showed shepherds dancing with nymphs, and there was just a suggestion of expensive sin. 'You were with him that night in Cologne. The night he got into the fight.' 'Extraordinary,' said Crabbe. 'Really. Do you like water?' he asked, and added a little to each of their glasses, but it was no more than a tear shed for the sober. 'Don't know what came over him.' 'Did you often go out with him?' He grinned unsuccessfully and they drank. 'That was five years ago, you see. Mary's mother was ill; kept on flogging back to England. I was a grass widower, so to speak.' 'So you'd push off with Leo occasionally; have a drink and chase a few pussycats.' 'More or less.' 'In Cologne?' 'Steady, old boy,' said Crabbe. 'You're like a bloody lawyer.' He drank again and as the drink went into him he shook like a poor comedian reacting late. 'Christ,' he said. 'What a day. Christ.' 'Night clubs are best in Cologne, are they?' 'You can't do it _here_ , old boy,' Crabbe said with a nervous start. 'Not unless you want to screw half the Government. You've got to be _bloody_ careful in Bonn.' He added needlessly, ' _Bloody_ careful.' He jerked his head in wild confirmation. 'Cologne's the better bet.' 'Better girls?' 'Can't make it, old boy. Not for years.' 'But Leo went for them, did he?' 'He liked the girls,' said Crabbe. 'So you went to Cologne that night. Your wife was in England, and you went on the razzle with Leo.' 'We were just sitting at a table. Drinking, you see.' He suited the gesture to the word. 'Leo was talking about the Army: remember old so-and-so. That game. Loved the Army, Leo did, loved it. Should have stayed in, that's my feeling. Not that they'd have had him, not as a regular. He needed the discipline, in my opinion. Urchin really. Like me. It's all right when you're young, you don't mind. It's later. They knocked hell out of me at Sherborne. Hell. Used to hold the taps, head in the basin, while the bloody prefects hit me. I didn't care then. Thought it was life.' He put a hand on Turner's arm. 'Old boy,' he whispered. 'I _hate_ them now. Didn't know I had it in me. It's all come to the surface. For two pins I'd go back there and shoot the buggers. Truth.' 'Did you know him in the Army?' 'No.' 'Then who were you remembering?' 'I ran across him in the CCG a bit. Moenchengladbach. Four Group.' 'When he was on Claims?' Crabbe's reaction to harassment was unnerving. Like his namesake he seemed in some mysterious way to draw the extremities of his presence under a protective shell, and to lie passive until the danger had passed. Ducking his head into his glass he kept it there, shoulders hunched, while he peered at Turner with pink, hooded eyes. 'So you were drinking and talking.' 'Just quietly. Waiting for the cabaret. I like a good cabaret.' He drifted away into a wholly incredible account of an attempt he had made upon a girl in Frankfurt on the occasion of the last Free Democrats' Conference: 'Fiasco,' he declared proudly. 'Climbing over me like a bloody monkey and I couldn't do a thing.' 'So the fight came after the cabaret?' 'Before