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<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@<mask_1:5>H]2COC[C@H]2Cc2ccncc2)cc1C(C)C<mask_1:5> | 0 | 22 | 5 | 5 | COc1ccc(S(=O)(=O)N[C@@H][C@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | H][C@ |
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<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@H]2<mask_1:6>C[C@H]2Cc2ccncc2)cc1C(C)C<mask_1:6> | 2 | 25 | 6 | CO | 6 | COc1ccc(S(=O)(=O)N[C@@H]2C(=O)NC[C@H]2Cc2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | C(=O)N |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2<mask_1:2>cncc2)cc1C(C)C<mask_1:2> | 4 | 34 | 2 | Cc2c | 2 | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2n2cncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | n2 |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2<mask_1:7>cc2)cc1C(C)C<mask_1:7> | 3 | 37 | 7 | ccn | 7 | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2cnc(OC)cc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | cnc(OC) |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@H<mask_1:5>]2COC[C@H]2Cc2ccncc2)cc1C(C)C<mask_1:5> | 0 | 23 | 5 | 5 | COc1ccc(S(=O)(=O)N[C@@H][C@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | ][C@H |
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<|startoftext|><L>COc1ccc(S(=O)<mask_1:2>=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C<mask_1:2> | 1 | 13 | 2 | ( | 2 | COc1ccc(S(=O)(C=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | (C |
<|startoftext|><L>C<mask_1:6>Oc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C<mask_1:6> | 0 | 1 | 6 | 6 | COC(=O)Oc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | OC(=O) |
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<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]<mask_1:5>ncc2)cc1C(C)C<mask_1:5> | 6 | 33 | 5 | 2Cc2cc | 5 | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2c2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | 2c2cc |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc<mask_1:6>C(C)C<mask_1:6> | 5 | 42 | 6 | 2)cc1 | 6 | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1OC(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | 2)cc1O |
<|startoftext|><L>COc1ccc(S(=O)(=O<mask_1:2>N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C<mask_1:2> | 1 | 16 | 2 | ) | 2 | COc1ccc(S(=O)(=O)NN[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | COc1ccc(S(=O)(=O)N[C@@H]2COC[C@H]2Cc2ccncc2)cc1C(C)C | )N |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)<mask_1:6>C2)cc1C<mask_1:6> | 7 | 40 | 6 | c(C)c3) | 6 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)cc3OC)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | cc3OC) |
<|startoftext|><L>COc1ccc(S(=O)(=O)<mask_1:8>[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C<mask_1:8> | 1 | 17 | 8 | N | 8 | COc1ccc(S(=O)(=O)NC(=O)NC[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | NC(=O)NC |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc<mask_1:7>C)c3)C2)cc1C<mask_1:7> | 5 | 37 | 7 | (C)c( | 7 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3cccc(OC(C)C)c3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | c(OC(C) |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c<mask_1:5>2)cc1C<mask_1:5> | 7 | 41 | 5 | (C)c3)C | 5 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)cc3C)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | c3C)C |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3c<mask_1:6>c(C)c3)C2)cc1C<mask_1:6> | 5 | 35 | 6 | cc(C) | 6 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(OC)c(C)c3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | cc(OC) |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@<mask_1:3>2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C<mask_1:3> | 2 | 21 | 3 | H] | 3 | COc1ccc(S(=O)(=O)N[C@@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | @H] |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)<mask_1:2>3)C2)cc1C<mask_1:2> | 5 | 40 | 2 | c(C)c | 2 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)cc3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | cc |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)<mask_1:8>ccc(C)c(C)c3)C2)cc1C<mask_1:8> | 4 | 30 | 8 | N(c3 | 8 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(CCCOc3ccc(C)c(C)c3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | N(CCCOc3 |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3cc<mask_1:7>c3)C2)cc1C<mask_1:7> | 8 | 36 | 7 | c(C)c(C) | 7 | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C#N)cc3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | c(C#N)c |
<|startoftext|><L>COc1ccc(S(=O)(=O)N[<mask_1:5>=O)N(c3ccc(C)c(C)c3)C2)cc1C<mask_1:5> | 8 | 19 | 5 | C@H]2CC( | 5 | COc1ccc(S(=O)(=O)N[S@]2(=O)N(c3ccc(C)c(C)c3)C2)cc1C | COc1ccc(S(=O)(=O)N[C@H]2CC(=O)N(c3ccc(C)c(C)c3)C2)cc1C | S@]2( |
<|startoftext|><L>C=CCCS(=O)(=O)Nc1cccc(-c2ncn<mask_1:2>C)n2)c1<mask_1:2> | 1 | 28 | 2 | ( | 2 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(CC)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | (C |
<|startoftext|><L>C=CCCS<mask_1:5>(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1<mask_1:5> | 0 | 6 | 5 | 5 | C=CCCS(=O)S(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | (=O)S |
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<|startoftext|><L>C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C<mask_1:4>)n2)c1<mask_1:4> | 0 | 30 | 4 | 4 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C(C)C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | (C)C |
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<|startoftext|><L>C=CCCS(=O)(=<mask_1:3>1cccc(-c2ncn(C)n2)c1<mask_1:3> | 4 | 12 | 3 | O)Nc | 3 | C=CCCS(=O)(=O)c1cccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | O)c |
<|startoftext|><L>C=CCCS(=O)(=<mask_1:3>Nc1cccc(-c2ncn(C)n2)c1<mask_1:3> | 2 | 12 | 3 | O) | 3 | C=CCCS(=O)(=O)CNc1cccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | O)C |
<|startoftext|><L>C=CCCS(=O)(=O)Nc1cccc(-c2nc<mask_1:5>n2)c1<mask_1:5> | 4 | 27 | 5 | n(C) | 5 | C=CCCS(=O)(=O)Nc1cccc(-c2ncc(C)cn2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | c(C)c |
<|startoftext|><L>C=CCCS(=O)<mask_1:1>Nc1cccc(-c2ncn(C)n2)c1<mask_1:1> | 4 | 10 | 1 | (=O) | 1 | C=CCCS(=O)=Nc1cccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | = |
<|startoftext|><L>C=C<mask_1:1>(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1<mask_1:1> | 3 | 3 | 1 | CCS | 1 | C=CS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | S |
<|startoftext|><L>C=CCCS(=O)(=O)Nc<mask_1:5>ccc(-c2ncn(C)n2)c1<mask_1:5> | 2 | 16 | 5 | 1c | 5 | C=CCCS(=O)(=O)Nc1c(F)ccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | 1c(F) |
<|startoftext|><L><mask_1:5>CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1<mask_1:5> | 2 | 0 | 5 | C= | 5 | CC(C)CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | C=CCCS(=O)(=O)Nc1cccc(-c2ncn(C)n2)c1 | CC(C) |
<|startoftext|><L>Cc1<mask_1:5>cc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C<mask_1:5> | 1 | 3 | 5 | c | 5 | Cc1c(Cl)cc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | c(Cl) |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2CCCC2)<mask_1:2>=O)=O)cc1C<mask_1:2> | 5 | 25 | 2 | S(C)( | 2 | Cc1ccc(N(CCCC(=O)N2CCCC2)S(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | S( |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)<mask_1:2>)=O)cc1C<mask_1:2> | 3 | 29 | 2 | (=O | 2 | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(C)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | (C |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=<mask_1:6>1C<mask_1:6> | 4 | 34 | 6 | O)cc | 6 | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)c(C)1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | O)c(C) |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2C<mask_1:5>CC2)S(C)(=O)=O)cc1C<mask_1:5> | 1 | 20 | 5 | C | 5 | Cc1ccc(N(CCCC(=O)N2CCC(C)CC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | CC(C) |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2C<mask_1:5>C2)S(C)(=O)=O)cc1C<mask_1:5> | 2 | 20 | 5 | CC | 5 | Cc1ccc(N(CCCC(=O)N2CCCCCCC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | CCCCC |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2<mask_1:2>2)S(C)(=O)=O)cc1C<mask_1:2> | 4 | 19 | 2 | CCCC | 2 | Cc1ccc(N(CCCC(=O)N2CC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | CC |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)N2C<mask_1:2>CC2)S(C)(=O)=O)cc1C<mask_1:2> | 1 | 20 | 2 | C | 2 | Cc1ccc(N(CCCC(=O)N2CCOCC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | CO |
<|startoftext|><L>Cc1ccc<mask_1:4>CC(=O)N2CCCC2)S(C)(=O)=O)cc1C<mask_1:4> | 5 | 6 | 4 | (N(CC | 4 | Cc1ccc(N(CCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | (N(C |
<|startoftext|><L>Cc1ccc(N(CCCC(=O)<mask_1:4>CCCC2)S(C)(=O)=O)cc1C<mask_1:4> | 2 | 17 | 4 | N2 | 4 | Cc1ccc(N(CCCC(=O)N2CCCCCC2)S(C)(=O)=O)cc1C | Cc1ccc(N(CCCC(=O)N2CCCC2)S(C)(=O)=O)cc1C | N2CC |
<|startoftext|><L>CCc1n<mask_1:5>3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1<mask_1:5> | 7 | 5 | 5 | n2c(ncc | 5 | CCc1nn2c(c3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | n2c(c |
<|startoftext|><L>CCc1nn2c(ncc3c(=O)n(-c4cccc<mask_1:5>ccc32)c1-c1ccccc1<mask_1:5> | 4 | 27 | 5 | c4F) | 5 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4OC)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | c4OC) |
<|startoftext|><L>CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc3<mask_1:4>c1-c1ccccc1<mask_1:4> | 2 | 35 | 4 | 2) | 4 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)ccc1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | 2)cc |
<|startoftext|><L>CCc1nn2c(ncc3c(=O)n(-c4c<mask_1:7>cc4F)ccc32)c1-c1ccccc1<mask_1:7> | 2 | 24 | 7 | cc | 7 | CCc1nn2c(ncc3c(=O)n(-c4ccc(C#N)cc4F)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | cc(C#N) |
<|startoftext|><L>CCc1nn2c(ncc3c(=O)n(-c4ccccc4F<mask_1:5>)c1-c1ccccc1<mask_1:5> | 6 | 30 | 5 | )ccc32 | 6 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | )ccc32 |
<|startoftext|><L>CCc1nn2c(ncc3c(=O)n(-c4ccc<mask_1:5>)ccc32)c1-c1ccccc1<mask_1:5> | 4 | 26 | 5 | cc4F | 5 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4OC)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | cc4OC |
<|startoftext|><L>CCc1nn2c(ncc3c(=<mask_1:5>)n(-c4ccccc4F)ccc32)c1-c1ccccc1<mask_1:5> | 1 | 16 | 5 | O | 5 | CCc1nn2c(ncc3c(=O)n(C)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | O)n(C |
<|startoftext|><L>CCc1nn2c(ncc3c(=O)n(-c4ccccc4<mask_1:3>32)c1-c1ccccc1<mask_1:3> | 5 | 29 | 3 | F)ccc | 4 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | )ccc |
<|startoftext|><L><mask_1:1>c1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1<mask_1:1> | 2 | 0 | 1 | CC | 1 | Cc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | C |
<|startoftext|><L><mask_1:4>2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1<mask_1:4> | 6 | 0 | 4 | CCc1nn | 4 | c1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | CCc1nn2c(ncc3c(=O)n(-c4ccccc4F)ccc32)c1-c1ccccc1 | c1nn |
<|startoftext|><L>CC(=O)N1C<mask_1:5>(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1<mask_1:5> | 2 | 9 | 5 | CC | 5 | CC(=O)N1CCC(C)(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(C) |
<|startoftext|><L>CC(=O)N1CCC(NC(=O<mask_1:6>c(-n3c(C)ccc3C)cc2)CC1<mask_1:6> | 5 | 17 | 6 | )c2cc | 6 | CC(=O)N1CCC(NC(=O)Cc2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | )Cc2cc |
<|startoftext|><L>CC(=O)N1CCC(NC(=O)c2ccc<mask_1:3>n3c(C)ccc3C)cc2)CC1<mask_1:3> | 2 | 23 | 3 | (- | 3 | CC(=O)N1CCC(NC(=O)c2ccc(OCn3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | (OC |
<|startoftext|><L>CC(=O)N1CCC(NC(=O)c2ccc(-n3c<mask_1:5>cc3C)cc2)CC1<mask_1:5> | 4 | 28 | 5 | (C)c | 5 | CC(=O)N1CCC(NC(=O)c2ccc(-n3cc(Cl)cc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | c(Cl) |
<|startoftext|><L>CC(=O)N1C<mask_1:3>C(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1<mask_1:3> | 4 | 9 | 3 | CC(N | 3 | CC(=O)N1CCN(C(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CN( |
<|startoftext|><L>C<mask_1:3>)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1<mask_1:3> | 4 | 1 | 3 | C(=O | 3 | CC(C)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | C(C |
<|startoftext|><L>CC(=O)N1CCC(NC(=O)c2c<mask_1:1>n3c(C)ccc3C)cc2)CC1<mask_1:1> | 4 | 21 | 1 | cc(- | 1 | CC(=O)N1CCC(NC(=O)c2c(n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | ( |
<|startoftext|><L>CC(=O)N1CCC<mask_1:5>(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1<mask_1:5> | 0 | 11 | 5 | 5 | CC(=O)N1CCC[C@H](NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | [C@H] |
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<|startoftext|><L>C<mask_1:1>O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1<mask_1:1> | 3 | 1 | 1 | C(= | 1 | C(O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | ( |
<|startoftext|><L>CC<mask_1:3>CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1<mask_1:3> | 6 | 2 | 3 | (=O)N1 | 3 | CCCN1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CC(=O)N1CCC(NC(=O)c2ccc(-n3c(C)ccc3C)cc2)CC1 | CN1 |
<|startoftext|><L>CCN1CCC[C@@H]1c1c<mask_1:4>ccnc1N(C)C<mask_1:4> | 0 | 17 | 4 | 4 | CCN1CCC[C@@H]1c1c(Br)ccnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | (Br) |
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<|startoftext|><L>CCN1CCC[C@@H]1c1cccnc1N(<mask_1:2>)C<mask_1:2> | 1 | 24 | 2 | C | 2 | CCN1CCC[C@@H]1c1cccnc1N(CC)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | CC |
<|startoftext|><L>CCN1CCC[C@@H]1c1c<mask_1:1>nc1N(C)C<mask_1:1> | 2 | 17 | 1 | cc | 1 | CCN1CCC[C@@H]1c1csnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | s |
<|startoftext|><L>CCN1CCC[C@@<mask_1:1>1c1cccnc1N(C)C<mask_1:1> | 2 | 11 | 1 | H] | 1 | CCN1CCC[C@@]1c1cccnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | ] |
<|startoftext|><L><mask_1:3>CCC[C@@H]1c1cccnc1N(C)C<mask_1:3> | 4 | 0 | 3 | CCN1 | 3 | CN1CCC[C@@H]1c1cccnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | CN1 |
<|startoftext|><L>CCN1CCC[C<mask_1:1>]1c1cccnc1N(C)C<mask_1:1> | 3 | 9 | 1 | @@H | 1 | CCN1CCC[CH]1c1cccnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | H |
<|startoftext|><L>CCN1C<mask_1:1>[C@@H]1c1cccnc1N(C)C<mask_1:1> | 2 | 5 | 1 | CC | 1 | CCN1CC[C@@H]1c1cccnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | C |
<|startoftext|><L><mask_1:4>CN1CCC[C@@H]1c1cccnc1N(C)C<mask_1:4> | 1 | 0 | 4 | C | 4 | COCCCN1CCC[C@@H]1c1cccnc1N(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | COCC |
<|startoftext|><L>CCN1CCC[C@@H]1c1cccnc1N(C<mask_1:4>C<mask_1:4> | 1 | 25 | 4 | ) | 4 | CCN1CCC[C@@H]1c1cccnc1N(CC)CCC | CCN1CCC[C@@H]1c1cccnc1N(C)C | C)CC |
<|startoftext|><L>CCN1CCC[C@@H]1c1cccnc1<mask_1:4>C)C<mask_1:4> | 2 | 22 | 4 | N( | 4 | CCN1CCC[C@@H]1c1cccnc1NCC(C)C | CCN1CCC[C@@H]1c1cccnc1N(C)C | NCC( |
<|startoftext|><L>Oc1nc(CN2CCCN(c3ccccc3)CC2)n<mask_1:4>c12<mask_1:4> | 5 | 28 | 4 | c2ccs | 4 | Oc1nc(CN2CCCN(c3ccccc3)CC2)n2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | 2ccs |
<|startoftext|><L>Oc1nc(CN2CCCN(<mask_1:3>ccc3)CC2)nc2ccsc12<mask_1:3> | 4 | 14 | 3 | c3cc | 3 | Oc1nc(CN2CCCN(c3sccc3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | c3s |
<|startoftext|><L>Oc1nc(C<mask_1:1>CCN(c3ccccc3)CC2)nc2ccsc12<mask_1:1> | 3 | 7 | 1 | N2C | 1 | Oc1nc(C2CCN(c3ccccc3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | 2 |
<|startoftext|><L>Oc1nc(CN2CCCN(c3ccc<mask_1:5>CC2)nc2ccsc12<mask_1:5> | 4 | 19 | 5 | cc3) | 5 | Oc1nc(CN2CCCN(c3ccccn3)CCC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | cn3)C |
<|startoftext|><L>Oc1nc(CN2CCCN(c3ccc<mask_1:3>CC2)nc2ccsc12<mask_1:3> | 4 | 19 | 3 | cc3) | 3 | Oc1nc(CN2CCCN(c3cccs3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | s3) |
<|startoftext|><L>Oc1nc<mask_1:3>CCCN(c3ccccc3)CC2)nc2ccsc12<mask_1:3> | 4 | 5 | 3 | (CN2 | 3 | Oc1nc(N2CCCN(c3ccccc3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | (N2 |
<|startoftext|><L>Oc1nc(CN2CCCN(c3cc<mask_1:5>3)CC2)nc2ccsc12<mask_1:5> | 3 | 18 | 5 | ccc | 5 | Oc1nc(CN2CCCN(c3cc[nH]n3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | [nH]n |
<|startoftext|><L>Oc1nc(CN2CCCN(c3cccc<mask_1:4>3)CC2)nc2ccsc12<mask_1:4> | 1 | 20 | 4 | c | 4 | Oc1nc(CN2CCCN(c3cccc(F)c3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | (F)c |
<|startoftext|><L>Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2c<mask_1:5>12<mask_1:5> | 3 | 31 | 5 | csc | 4 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccccc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | cccc |
<|startoftext|><L>Oc1nc(CN2CCCN<mask_1:3>3ccccc3)CC2)nc2ccsc12<mask_1:3> | 2 | 13 | 3 | (c | 3 | Oc1nc(CN2CCCN(Cc3ccccc3)CC2)nc2ccsc12 | Oc1nc(CN2CCCN(c3ccccc3)CC2)nc2ccsc12 | (Cc |
<|startoftext|><L>CCNC(=<mask_1:5>N(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:5> | 3 | 6 | 5 | O)C | 5 | CCNC(=O)CCCN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | O)CCC |
<|startoftext|><L>CCNC(=O)CN(C)C(=O)c1cc(-c2cc(<mask_1:3>C)c(OC)c(OC)c2)nc2ccccc12<mask_1:3> | 1 | 29 | 3 | O | 3 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OCCC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | OCC |
<|startoftext|><L>CCNC(=O)CN(<mask_1:2>c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:2> | 7 | 11 | 2 | C)C(=O) | 2 | CCNC(=O)CN(C)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | C) |
<|startoftext|><L>CCNC(=O)CN<mask_1:4>C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:4> | 3 | 10 | 4 | (C) | 4 | CCNC(=O)CN(CC)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | (CC) |
<|startoftext|><L>CCNC(=O)CN(C)C(=O)<mask_1:7>cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:7> | 2 | 18 | 7 | c1 | 7 | CCNC(=O)CN(C)C(=O)/C=C/c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | /C=C/c1 |
<|startoftext|><L>CC<mask_1:4>=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:4> | 3 | 2 | 4 | NC( | 4 | CCCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CNC( |
<|startoftext|><L>CCNC(=O)CN(C)C(=O)c1cc(-c<mask_1:7>OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:7> | 4 | 25 | 7 | 2cc( | 7 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OCCOC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | 2cc(OCC |
<|startoftext|><L>CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2<mask_1:8>cccc12<mask_1:8> | 5 | 44 | 8 | )nc2c | 8 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2c(C)cccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | )nc2c(C) |
<|startoftext|><L>CCNC(<mask_1:6>N(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:6> | 4 | 5 | 6 | =O)C | 6 | CCNC(=O)CCCN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | =O)CCC |
<|startoftext|><L>CCNC(=O)CN(C)C(=O)c1cc(<mask_1:7>c2cc(OC)c(OC)c(OC)c2)nc2ccccc12<mask_1:7> | 1 | 23 | 7 | - | 7 | CCNC(=O)CN(C)C(=O)c1cc(NC(=O)Cc2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | CCNC(=O)CN(C)C(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2ccccc12 | NC(=O)C |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN<mask_1:2>c2cccc(Br)c2)C1)c1ccc(Cl)nc1<mask_1:2> | 1 | 19 | 2 | ( | 2 | O=S(=O)(NC[C@H]1CCN(Cc2cccc(Br)c2)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | (C |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(c2cccc<mask_1:3>Br)c2)C1)c1ccc(Cl)nc1<mask_1:3> | 1 | 26 | 3 | ( | 3 | O=S(=O)(NC[C@H]1CCN(c2cccc(CCBr)c2)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | (CC |
<|startoftext|><L>O=S(=O)(NC[C@H]1CC<mask_1:7>cc(Br)c2)C1)c1ccc(Cl)nc1<mask_1:7> | 6 | 18 | 7 | N(c2cc | 7 | O=S(=O)(NC[C@H]1CCN(Cc2cccc(Br)c2)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | N(Cc2cc |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1c<mask_1:3>l)nc1<mask_1:3> | 4 | 39 | 3 | cc(C | 3 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1cn(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | n(C |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c<mask_1:4>C1)c1ccc(Cl)nc1<mask_1:4> | 2 | 31 | 4 | 2) | 4 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2Cl)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | 2Cl) |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(c2cc<mask_1:4>cc(Br)c2)C1)c1ccc(Cl)nc1<mask_1:4> | 0 | 24 | 4 | 4 | O=S(=O)(NC[C@H]1CCN(c2cc(Cl)cc(Br)c2)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | (Cl) |
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<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(c2cccc<mask_1:5>C1)c1ccc(Cl)nc1<mask_1:5> | 7 | 26 | 5 | (Br)c2) | 5 | O=S(=O)(NC[C@H]1CCN(c2ccccc2Cl)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | c2Cl) |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(<mask_1:4>c(Br)c2)C1)c1ccc(Cl)nc1<mask_1:4> | 5 | 20 | 4 | c2ccc | 4 | O=S(=O)(NC[C@H]1CCN(c2scc(Br)c2)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | c2sc |
<|startoftext|><L>O=S(=O)(NC<mask_1:7>]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1<mask_1:7> | 4 | 10 | 7 | [C@H | 7 | O=S(=O)(NCCO[C@@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | CO[C@@H |
<|startoftext|><L>O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2<mask_1:1>)C1)c1ccc(Cl)nc1<mask_1:1> | 0 | 32 | 1 | 1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2O)C1)c1ccc(Cl)nc1 | O=S(=O)(NC[C@H]1CCN(c2cccc(Br)c2)C1)c1ccc(Cl)nc1 | O |