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<|startoftext|><L>O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(<mask_1:5>)c(O)ccc12<mask_1:5> | 1 | 31 | 5 | O | 5 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(CN(C))c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | CN(C) |
<|startoftext|><L>O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)<mask_1:4>)ccc12<mask_1:4> | 3 | 33 | 4 | c(O | 4 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(Cl)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | c(Cl |
<|startoftext|><L>O=c1c(<mask_1:6>2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12<mask_1:6> | 2 | 6 | 6 | -c | 6 | O=c1c(/C=N/c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | /C=N/c |
<|startoftext|><L>O=c1c(-c2ccc3c(c2)OCCCO3)coc2c<mask_1:5>(O)ccc12<mask_1:5> | 4 | 30 | 5 | (O)c | 5 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(CN)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | (CN)c |
<|startoftext|><L>O=c1c(-c2ccc3c(c2)OCCCO3)coc2<mask_1:1>c(O)ccc12<mask_1:1> | 4 | 29 | 1 | c(O) | 1 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2cc(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | c |
<|startoftext|><L>O=c1c(-c2ccc3c(c2)OCC<mask_1:5>c2c(O)c(O)ccc12<mask_1:5> | 6 | 21 | 5 | CO3)co | 5 | O=c1c(-c2ccc3c(c2)OCCO3)coc2c(O)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | O3)co |
<|startoftext|><L>O=c1c(-c2ccc3c(<mask_1:5>CCCO3)coc2c(O)c(O)ccc12<mask_1:5> | 4 | 15 | 5 | c2)O | 5 | O=c1c(-c2ccc3c(c2)OCCCCO3)coc2c(O)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | c2)OC |
<|startoftext|><L>O=c1c(-c2ccc3c(c2)OC<mask_1:2>)coc2c(O)c(O)ccc12<mask_1:2> | 4 | 20 | 2 | CCO3 | 2 | O=c1c(-c2ccc3c(c2)OCO3)coc2c(O)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | O3 |
<|startoftext|><L>O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(<mask_1:5>O)c(O)ccc12<mask_1:5> | 0 | 31 | 5 | 5 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(CN(C)O)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | CN(C) |
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<|startoftext|><L>O=c1c(-c2ccc3c(<mask_1:3>CCO3)coc2c(O)c(O)ccc12<mask_1:3> | 5 | 15 | 3 | c2)OC | 3 | O=c1c(-c2ccc3c(c2)CCO3)coc2c(O)c(O)ccc12 | O=c1c(-c2ccc3c(c2)OCCCO3)coc2c(O)c(O)ccc12 | c2) |
<|startoftext|><L>C=C(C)C<mask_1:5>Sc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4<mask_1:5> | 0 | 7 | 5 | 5 | C=C(C)C(=O)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | (=O)C |
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<|startoftext|><L>C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C<mask_1:4>@H](C)CC4<mask_1:4> | 3 | 35 | 4 | [C@ | 4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)CC[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C[C@ |
<|startoftext|><L>C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@<mask_1:7>C)CC4<mask_1:7> | 4 | 38 | 7 | @H]( | 7 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@](C)(CC)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | @](C)(C |
<|startoftext|><L>C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[<mask_1:5>C)CC4<mask_1:5> | 6 | 36 | 5 | C@@H]( | 5 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C@H]( |
<|startoftext|><L>C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C<mask_1:6>H](C)CC4<mask_1:6> | 4 | 35 | 6 | [C@@ | 5 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)CC[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C[C@@ |
<|startoftext|><L>C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@<mask_1:5>CC4<mask_1:5> | 6 | 38 | 5 | @H](C) | 5 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | H](C) |
<|startoftext|><L>C=C(C)C<mask_1:2>Sc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4<mask_1:2> | 0 | 7 | 2 | 2 | C=C(C)CCCSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | CC |
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<|startoftext|><L>C=C(C)CSc1nnc2n3n<mask_1:6>cnc3c3c4c(sc3n12)C[C@@H](C)CC4<mask_1:6> | 0 | 17 | 6 | 6 | C=C(C)CSc1nnc2n3nc(CC)ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | c(CC)n |
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<|startoftext|><L>C=C(C<mask_1:7>nc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4<mask_1:7> | 6 | 5 | 7 | )CSc1n | 7 | C=C(Cl)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | l)CSc1n |
<|startoftext|><L>C=C(C)CSc1nnc2n<mask_1:7>ncnc3c3c4c(sc3n12)C[C@@H](C)CC4<mask_1:7> | 1 | 15 | 7 | 3 | 7 | C=C(C)CSc1nnc2n(C)cc3-ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | C=C(C)CSc1nnc2n3ncnc3c3c4c(sc3n12)C[C@@H](C)CC4 | (C)cc3- |
<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)<mask_1:4>CC2)C3)n1<mask_1:4> | 7 | 36 | 4 | CC2=CCC | 4 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)C2CCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | C2CC |
<|startoftext|><L>CSc1ncc<mask_1:3>-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1<mask_1:3> | 2 | 7 | 3 | c( | 3 | CSc1nccc(N-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | c(N |
<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H<mask_1:5>(CNC(=O)CC2=CCCCC2)C3)n1<mask_1:5> | 1 | 27 | 5 | ] | 5 | CSc1nccc(-c2cc(F)cc3c2O[C@H](C)C(CNC(=O)CC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | ](C)C |
<|startoftext|><L>CSc1nccc(-c2cc(F)<mask_1:6>3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1<mask_1:6> | 2 | 17 | 6 | cc | 6 | CSc1nccc(-c2cc(F)c(Cl)c3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | c(Cl)c |
<|startoftext|><L>CSc1ncc<mask_1:3>c(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1<mask_1:3> | 6 | 7 | 3 | c(-c2c | 3 | CSc1ncc2c(c(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | 2c( |
<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)<mask_1:3>1<mask_1:3> | 4 | 47 | 3 | C3)n | 4 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | C3)n |
<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=<mask_1:5>O)CC2=CCCCC2)C3)n1<mask_1:5> | 0 | 34 | 5 | 5 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)C(=O)CC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | O)C(= |
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<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H](C<mask_1:2>CC2=CCCCC2)C3)n1<mask_1:2> | 6 | 30 | 2 | NC(=O) | 2 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNCCC2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | NC |
<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(<mask_1:5>=CCCCC2)C3)n1<mask_1:5> | 6 | 33 | 5 | =O)CC2 | 5 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)C2=CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | =O)C2 |
<|startoftext|><L>CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2<mask_1:3>CCCCC2)C3)n1<mask_1:3> | 1 | 39 | 3 | = | 3 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2(O)CCCCC2)C3)n1 | CSc1nccc(-c2cc(F)cc3c2O[C@H](CNC(=O)CC2=CCCCC2)C3)n1 | (O) |
<|startoftext|><L>Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc<mask_1:5>2<mask_1:5> | 1 | 37 | 5 | 1 | 5 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc1C(C)2 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | 1C(C) |
<|startoftext|><L>Cc1c(C(=O)NC(C)(C)C(=<mask_1:3>O)oc2c(Cl)cccc12<mask_1:3> | 2 | 21 | 3 | O) | 3 | Cc1c(C(=O)NC(C)(C)C(=O)CO)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | O)C |
<|startoftext|><L>Cc1c(C(=O)NC(C)(<mask_1:4>C(=O)O)oc2c(Cl)cccc12<mask_1:4> | 2 | 16 | 4 | C) | 4 | Cc1c(C(=O)NC(C)(C)CCC(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | C)CC |
<|startoftext|><L>Cc1c<mask_1:4>=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12<mask_1:4> | 3 | 4 | 4 | (C( | 4 | Cc1c(CC(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | (CC( |
<|startoftext|><L>Cc1c(C<mask_1:4>C(C)(C)C(=O)O)oc2c(Cl)cccc12<mask_1:4> | 5 | 6 | 4 | (=O)N | 4 | Cc1c(C(=O)C(C)(C)C(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | (=O) |
<|startoftext|><L>Cc1c(C(=O)<mask_1:3>C(C)(C)C(=O)O)oc2c(Cl)cccc12<mask_1:3> | 1 | 10 | 3 | N | 3 | Cc1c(C(=O)NCCC(C)(C)C(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | NCC |
<|startoftext|><L>Cc1<mask_1:4>(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12<mask_1:4> | 3 | 3 | 4 | c(C | 4 | Cc1c(CC(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | c(CC |
<|startoftext|><L>Cc1c(C(=O)NC(C)(<mask_1:5>=O)O)oc2c(Cl)cccc12<mask_1:5> | 4 | 16 | 5 | C)C( | 5 | Cc1c(C(=O)NC(C)(C)CC(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | C)CC( |
<|startoftext|><L>Cc1c(C(=O)NC<mask_1:5>(C)C(=O)O)oc2c(Cl)cccc12<mask_1:5> | 3 | 12 | 5 | (C) | 5 | Cc1c(C(=O)NC[C@H](C)C(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | [C@H] |
<|startoftext|><L>Cc1c(C(=O)NC(C)<mask_1:1>C(=O)O)oc2c(Cl)cccc12<mask_1:1> | 3 | 15 | 1 | (C) | 1 | Cc1c(C(=O)NC(C)CC(=O)O)oc2c(Cl)cccc12 | Cc1c(C(=O)NC(C)(C)C(=O)O)oc2c(Cl)cccc12 | C |
<|startoftext|><L>COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)O<mask_1:2>)CC3)n2)cc1OC<mask_1:2> | 3 | 41 | 2 | CO5 | 2 | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | O5 |
<|startoftext|><L>COc1ccc(-c2noc(CCC(=O)N3C<mask_1:8>cc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:8> | 7 | 25 | 8 | CN(Cc4c | 8 | COc1ccc(-c2noc(CCC(=O)N3CCC(COc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | CC(COc4c |
<|startoftext|><L>COc1<mask_1:8>-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:8> | 4 | 4 | 8 | ccc( | 8 | COc1c(Cl)cc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | c(Cl)cc( |
<|startoftext|><L>COc1c<mask_1:7>-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:7> | 3 | 5 | 7 | cc( | 7 | COc1c(OC)cc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | (OC)cc( |
<|startoftext|><L>COc1ccc(-c2noc(CCC(=O)N3CCN(Cc<mask_1:1>c5c(c4)OCO5)CC3)n2)cc1OC<mask_1:1> | 3 | 30 | 1 | 4cc | 1 | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4c5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | 4 |
<|startoftext|><L>COc1ccc(-c2noc(CCC(=O)N3CCN(C<mask_1:8>ccc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:8> | 2 | 29 | 8 | c4 | 8 | COc1ccc(-c2noc(CCC(=O)N3CCN(CC(=O)Nc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | C(=O)Nc4 |
<|startoftext|><L>COc1ccc(-c2noc(CCC(=O)<mask_1:7>Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:7> | 6 | 22 | 7 | N3CCN( | 7 | COc1ccc(-c2noc(CCC(=O)N3CCN(CCc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | N3CCN(C |
<|startoftext|><L>COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4<mask_1:6>5c(c4)OCO5)CC3)n2)cc1OC<mask_1:6> | 3 | 31 | 6 | ccc | 6 | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4cc(C)c5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | cc(C)c |
<|startoftext|><L>COc1ccc(-c<mask_1:7>CC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:7> | 6 | 10 | 7 | 2noc(C | 7 | COc1ccc(-c2noc(CCCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | 2noc(CC |
<|startoftext|><L><mask_1:1>1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC<mask_1:1> | 3 | 0 | 1 | COc | 1 | c1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | COc1ccc(-c2noc(CCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)n2)cc1OC | c |
<|startoftext|><L>Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3cc<mask_1:6>c3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:6> | 2 | 34 | 6 | cc | 6 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccc(Cl)cc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | c(Cl)c |
<|startoftext|><L>Cc1c(C(=O)NN2<mask_1:5>[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:5> | 6 | 13 | 5 | C(=O)N | 5 | Cc1c(C(=O)NN2C(=O)[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | C(=O) |
<|startoftext|><L>Cc1c(C(=O)NN2C(=O)N<mask_1:7>@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:7> | 2 | 19 | 7 | [C | 7 | Cc1c(C(=O)NN2C(=O)NC(=O)[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | C(=O)[C |
<|startoftext|><L>Cc1c(C(=O)NN2C(=O<mask_1:5>)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:5> | 0 | 17 | 5 | 5 | Cc1c(C(=O)NN2C(=O)C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | )C(=O |
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<|startoftext|><L>Cc1c(C(=O)NN2C(=<mask_1:7>(C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:7> | 8 | 16 | 7 | O)N[C@@] | 7 | Cc1c(C(=O)NN2C(=O)N[C@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | O)N[C@] |
<|startoftext|><L>Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3<mask_1:9>nH]c2c1C(=O)CC(C)(C)C2<mask_1:9> | 7 | 38 | 9 | )C2=O)[ | 9 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)nn[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | )C2=O)nn[ |
<|startoftext|><L>Cc1c(C(=O)NN2C(=O)<mask_1:1>N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:1> | 0 | 18 | 1 | 1 | Cc1c(C(=O)NN2C(=O)CN[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | C |
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<|startoftext|><L>Cc1c(C(=O)N<mask_1:10>N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:10> | 7 | 11 | 10 | N2C(=O) | 10 | Cc1c(C(=O)NCCN2C(=O)CN[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | CCN2C(=O)C |
<|startoftext|><L>Cc<mask_1:4>N2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:4> | 9 | 2 | 4 | 1c(C(=O)N | 4 | Cc1c(CN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | 1c(C |
<|startoftext|><L><mask_1:9>c1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2<mask_1:9> | 1 | 0 | 9 | C | 9 | CCOC(=O)Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | Cc1c(C(=O)NN2C(=O)N[C@@](C)(CCc3ccccc3)C2=O)[nH]c2c1C(=O)CC(C)(C)C2 | CCOC(=O)C |
<|startoftext|><L>Cc1cc(C(=O<mask_1:6>H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:6> | 5 | 10 | 6 | )N[C@ | 6 | Cc1cc(C(=O)N[C@@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | )N[C@@ |
<|startoftext|><L>Cc1cc(C(=O)N[C@H]2CC<mask_1:3>CC3)C2)c2c(C)n[nH]c2n1<mask_1:3> | 7 | 20 | 3 | OC3(CCC | 3 | Cc1cc(C(=O)N[C@H]2CC3(CCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | 3(C |
<|startoftext|><L>Cc1cc(C(=O)N<mask_1:3>[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:3> | 0 | 12 | 3 | 3 | Cc1cc(C(=O)N(C)[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | (C) |
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<|startoftext|><L>C<mask_1:3>c1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:3> | 0 | 1 | 3 | 3 | COCCc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | OCC |
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<|startoftext|><L>Cc1cc(C(=O)N[C@H]<mask_1:4>2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:4> | 0 | 17 | 4 | 4 | Cc1cc(C(=O)N[C@H](C)N2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | (C)N |
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<|startoftext|><L>Cc1cc(C(<mask_1:4>C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:4> | 5 | 8 | 4 | =O)N[ | 4 | Cc1cc(C(=O)[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | =O)[ |
<|startoftext|><L>Cc1cc(C(=O)N<mask_1:4>@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:4> | 2 | 12 | 4 | [C | 4 | Cc1cc(C(=O)NC[C@@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | C[C@ |
<|startoftext|><L>Cc1cc(C(=O)N[C@H]2CCOC<mask_1:6>CCCC3)C2)c2c(C)n[nH]c2n1<mask_1:6> | 3 | 22 | 6 | 3(C | 6 | Cc1cc(C(=O)N[C@H]2CCOC3(CCOCCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | 3(CCOC |
<|startoftext|><L>Cc1cc(C(=O)N[C@<mask_1:1>2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1<mask_1:1> | 2 | 15 | 1 | H] | 1 | Cc1cc(C(=O)N[C@]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | ] |
<|startoftext|><L>Cc1cc(C(=O)N[C@H]2CCOC3(<mask_1:7>3)C2)c2c(C)n[nH]c2n1<mask_1:7> | 5 | 24 | 7 | CCCCC | 6 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCCC3)C2)c2c(C)n[nH]c2n1 | Cc1cc(C(=O)N[C@H]2CCOC3(CCCCC3)C2)c2c(C)n[nH]c2n1 | CCCCCC |
<|startoftext|><L>Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)<mask_1:4>1<mask_1:4> | 3 | 42 | 4 | C)s | 4 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)nc1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | C)nc |
<|startoftext|><L>C<mask_1:2>1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1<mask_1:2> | 1 | 1 | 2 | c | 2 | CCc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | Cc |
<|startoftext|><L>C<mask_1:5>[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1<mask_1:5> | 3 | 1 | 5 | c1n | 5 | CCCc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | CCc1n |
<|startoftext|><L><mask_1:4>n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1<mask_1:4> | 3 | 0 | 4 | Cc1 | 4 | CCc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | CCc1 |
<|startoftext|><L>Cc1n[<mask_1:5>H]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1<mask_1:5> | 1 | 5 | 5 | n | 5 | Cc1n[nH][nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | nH][n |
<|startoftext|><L>Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=<mask_1:6>cnc(CC(C)C)s1<mask_1:6> | 4 | 29 | 6 | O)c1 | 6 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)NCc1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | O)NCc1 |
<|startoftext|><L>Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc<mask_1:6>)C)s1<mask_1:6> | 5 | 36 | 6 | (CC(C | 6 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CCN(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | (CCN(C |
<|startoftext|><L>Cc1n<mask_1:2>]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1<mask_1:2> | 3 | 4 | 2 | [nH | 3 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | [nH |
<|startoftext|><L>Cc1n[nH]c(C)c1[C@@H]1CCCN1C<mask_1:1>c1cnc(CC(C)C)s1<mask_1:1> | 4 | 27 | 1 | (=O) | 1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1CCc1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | C |
<|startoftext|><L>Cc1n[nH]c(C)c1[C@@H]1CCC<mask_1:5>=O)c1cnc(CC(C)C)s1<mask_1:5> | 4 | 24 | 5 | N1C( | 5 | Cc1n[nH]c(C)c1[C@@H]1CCCCN1C(=O)c1cnc(CC(C)C)s1 | Cc1n[nH]c(C)c1[C@@H]1CCCN1C(=O)c1cnc(CC(C)C)s1 | CN1C( |
<|startoftext|><L>C[C@@H]1N(CCCn2cccn2)CC<mask_1:5>[C@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:5> | 1 | 23 | 5 | C | 5 | C[C@@H]1N(CCCn2cccn2)CC(=O)N[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | (=O)N |
<|startoftext|><L>C[C@@H]1N(CCCn2<mask_1:7>n2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:7> | 3 | 15 | 7 | ccc | 7 | C[C@@H]1N(CCCn2cc(CO)cn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | cc(CO)c |
<|startoftext|><L>C[C@@H]1N(CCCn2cccn2)<mask_1:7>CCC[C@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:7> | 0 | 21 | 7 | 7 | C[C@@H]1N(CCCn2cccn2)CC(=O)NCCC[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | CC(=O)N |
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<|startoftext|><L>C[C@@H]1N(C<mask_1:3>cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:3> | 4 | 11 | 3 | CCn2 | 3 | C[C@@H]1N(Cc2ccccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | c2c |
<|startoftext|><L>C[C@@H]1N(CCCn2cccn2)<mask_1:2>@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:2> | 5 | 21 | 2 | CCC[C | 2 | C[C@@H]1N(CCCn2cccn2)[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | [C |
<|startoftext|><L>C[C@@H]1N(CCCn2cc<mask_1:5>CCC[C@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:5> | 4 | 17 | 5 | cn2) | 5 | C[C@@H]1N(CCCn2ccnc2)CCCC[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | nc2)C |
<|startoftext|><L>C[C@@H]1N(CCCn2cccn2)CCC[C@@]<mask_1:2>CCN(Cc1ccccc1F)C2=O<mask_1:2> | 3 | 29 | 2 | 12C | 2 | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | 12 |
<|startoftext|><L>C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)<mask_1:2>2=O<mask_1:2> | 1 | 47 | 2 | C | 2 | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)CC2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | CC |
<|startoftext|><L>C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1cccc<mask_1:4>c1F)C2=O<mask_1:4> | 0 | 43 | 4 | 4 | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1cccc(Cl)c1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | (Cl) |
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<|startoftext|><L>C[C@@H]1N(CCC<mask_1:5>ccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O<mask_1:5> | 3 | 13 | 5 | n2c | 5 | C[C@@H]1N(CCCCc2ccccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | C[C@@H]1N(CCCn2cccn2)CCC[C@@]12CCCN(Cc1ccccc1F)C2=O | Cc2cc |
<|startoftext|><L>CCOc1ccc(CCC(=O)Nc2ccc<mask_1:7>=O)N[C@H](C)CC)cc1OCC<mask_1:7> | 5 | 22 | 7 | cc2C( | 7 | CCOc1ccc(CCC(=O)Nc2ccccc2SCC(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | cc2SCC( |
<|startoftext|><L>CCOc<mask_1:7>(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC<mask_1:7> | 4 | 4 | 7 | 1ccc | 7 | CCOc1cc(C)c(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | 1cc(C)c |
<|startoftext|><L>CCOc1ccc(CC<mask_1:2>C(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC<mask_1:2> | 0 | 11 | 2 | 2 | CCOc1ccc(CCCNC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CN |
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<|startoftext|><L>CCOc<mask_1:4>C(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC<mask_1:4> | 7 | 4 | 4 | 1ccc(CC | 4 | CCOc1oc(C(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | 1oc( |
<|startoftext|><L>CCOc1ccc<mask_1:3>=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC<mask_1:3> | 5 | 8 | 3 | (CCC( | 3 | CCOc1ccc(C(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | (C( |
<|startoftext|><L>CCOc1ccc(CCC(=O)Nc2ccccc2C(=<mask_1:6>N[C@H](C)CC)cc1OCC<mask_1:6> | 2 | 28 | 6 | O) | 6 | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)NCCCN[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | O)NCCC |
<|startoftext|><L>CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C<mask_1:6>)CC)cc1OCC<mask_1:6> | 0 | 38 | 6 | 6 | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](CC(=O)O)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | C(=O)O |
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<|startoftext|><L>CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)<mask_1:5>C)cc1OCC<mask_1:5> | 1 | 39 | 5 | C | 5 | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC(C)C)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CC(C) |
<|startoftext|><L><mask_1:7>1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC<mask_1:7> | 4 | 0 | 7 | CCOc | 7 | CC(=O)c1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CC(=O)c |
<|startoftext|><L>CCOc1ccc(CC<mask_1:7>c2ccccc2C(=O)N[C@H](C)CC)cc1OCC<mask_1:7> | 6 | 11 | 7 | C(=O)N | 7 | CCOc1ccc(CCNC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | CCOc1ccc(CCC(=O)Nc2ccccc2C(=O)N[C@H](C)CC)cc1OCC | NC(=O)N |