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<|startoftext|><L>COc1cc(<mask_1:5>2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2<mask_1:5> | 2 | 7 | 5 | -c | 5 | COc1cc(CCNCc2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | CCNCc |
<|startoftext|><L>COc1cc(-c2cnc3ccccc3c2)cc2c1OC<mask_1:8>)c1cccc(N3CCNC3=O)c1)C2<mask_1:8> | 7 | 30 | 8 | CN(C(=O | 8 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(CC(=O)c1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | CN(CC(=O |
<|startoftext|><L>COc1cc<mask_1:4>c3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2<mask_1:4> | 6 | 6 | 4 | (-c2cn | 4 | COc1cc(-c2c3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | (-c2 |
<|startoftext|><L>COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N<mask_1:5>O)c1)C2<mask_1:5> | 7 | 46 | 5 | 3CCNC3= | 5 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(NC(C)=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | C(C)= |
<|startoftext|><L>C<mask_1:1>Oc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2<mask_1:1> | 0 | 1 | 1 | 1 | CCOc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | C |
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<|startoftext|><L>COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N<mask_1:7>NC3=O)c1)C2<mask_1:7> | 3 | 46 | 7 | 3CC | 7 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3C(=O)CNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | 3C(=O)C |
<|startoftext|><L>COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(<mask_1:8>cc(N3CCNC3=O)c1)C2<mask_1:8> | 7 | 35 | 8 | =O)c1cc | 8 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)Cc1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | =O)Cc1cc |
<|startoftext|><L>COc1cc(-c2cnc3<mask_1:6>cc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2<mask_1:6> | 3 | 14 | 6 | ccc | 6 | COc1cc(-c2cnc3ccc(C)cc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | ccc(C) |
<|startoftext|><L>COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3<mask_1:2>3=O)c1)C2<mask_1:2> | 4 | 47 | 2 | CCNC | 2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | CC |
<|startoftext|><L>COc1cc(-c2cnc3ccccc3c2)cc2c<mask_1:9>(C(=O)c1cccc(N3CCNC3=O)c1)C2<mask_1:9> | 5 | 27 | 9 | 1OCCN | 9 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C)C(C(=O)c1cccc(N3CCNC3=O)c1)C2 | COc1cc(-c2cnc3ccccc3c2)cc2c1OCCN(C(=O)c1cccc(N3CCNC3=O)c1)C2 | 1OCCN(C)C |
<|startoftext|><L>C<mask_1:2>(CNCc2cncs2)cnn1C<mask_1:2> | 3 | 1 | 2 | c1c | 2 | Cc1(CNCc2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | c1 |
<|startoftext|><L>Cc1c(CNCc2c<mask_1:1>2)cnn1C<mask_1:1> | 3 | 11 | 1 | ncs | 1 | Cc1c(CNCc2cs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | s |
<|startoftext|><L>C<mask_1:2>c1c(CNCc2cncs2)cnn1C<mask_1:2> | 0 | 1 | 2 | 2 | CCCc1c(CNCc2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | CC |
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<|startoftext|><L>Cc1c(CNCc2cncs2)cn<mask_1:3>C<mask_1:3> | 2 | 18 | 3 | n1 | 3 | Cc1c(CNCc2cncs2)cnn1CC | Cc1c(CNCc2cncs2)cnn1C | n1C |
<|startoftext|><L>Cc1c(<mask_1:1>c2cncs2)cnn1C<mask_1:1> | 3 | 5 | 1 | CNC | 1 | Cc1c(-c2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | - |
<|startoftext|><L>Cc1c(CNCc2c<mask_1:3>s2)cnn1C<mask_1:3> | 2 | 11 | 3 | nc | 3 | Cc1c(CNCc2c(C)s2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | (C) |
<|startoftext|><L>C<mask_1:2>1c(CNCc2cncs2)cnn1C<mask_1:2> | 1 | 1 | 2 | c | 2 | COc1c(CNCc2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | Oc |
<|startoftext|><L><mask_1:3>1c(CNCc2cncs2)cnn1C<mask_1:3> | 2 | 0 | 3 | Cc | 3 | CCc1c(CNCc2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | CCc |
<|startoftext|><L>Cc1c(<mask_1:3>NCc2cncs2)cnn1C<mask_1:3> | 1 | 5 | 3 | C | 3 | Cc1c(OCCNCc2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | OCC |
<|startoftext|><L>Cc1c(CNC<mask_1:3>2cncs2)cnn1C<mask_1:3> | 1 | 8 | 3 | c | 3 | Cc1c(CNCCCc2cncs2)cnn1C | Cc1c(CNCc2cncs2)cnn1C | CCc |
<|startoftext|><L>Cc1cc<mask_1:2>cc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:2> | 0 | 5 | 2 | 2 | Cc1cccccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | cc |
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<|startoftext|><L><mask_1:8>Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:8> | 0 | 0 | 8 | 8 | CCN(CC)CCc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | CCN(CC)C |
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<|startoftext|><L>Cc1cccc<mask_1:5>noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:5> | 4 | 7 | 5 | (-c2 | 5 | Cc1cccc(OCc2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | (OCc2 |
<|startoftext|><L>Cc1cccc(-c2noc(CNC<mask_1:6>O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:6> | 2 | 18 | 6 | (= | 6 | Cc1cccc(-c2noc(CNCCCNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | CCNC(= |
<|startoftext|><L>Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4ccc<mask_1:3>C3)n2)c1<mask_1:3> | 4 | 42 | 3 | s4)C | 3 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)C3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | s4) |
<|startoftext|><L>Cc1cccc(-c2noc(CNC(=O)C3<mask_1:5>CN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:5> | 1 | 24 | 5 | C | 5 | Cc1cccc(-c2noc(CNC(=O)C3(C)CCCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | (C)CC |
<|startoftext|><L>Cc1cccc(-c2n<mask_1:7>C(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:7> | 5 | 12 | 7 | oc(CN | 7 | Cc1cccc(-c2n[nH]c(NC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | [nH]c(N |
<|startoftext|><L>Cc1cccc(-c2noc(C<mask_1:2>O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:2> | 4 | 16 | 2 | NC(= | 2 | Cc1cccc(-c2noc(C(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | (= |
<|startoftext|><L>Cc1cccc(-<mask_1:7>c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:7> | 0 | 9 | 7 | 7 | Cc1cccc(-n2cccc2c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | n2cccc2 |
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<|startoftext|><L>Cc1cccc(-c2noc(CNC(=O)C3CCN(<mask_1:3>S(=O)(=O)c4cccs4)CC3)n2)c1<mask_1:3> | 0 | 28 | 3 | 3 | Cc1cccc(-c2noc(CNC(=O)C3CCN(CCCS(=O)(=O)c4cccs4)CC3)n2)c1 | Cc1cccc(-c2noc(CNC(=O)C3CCN(S(=O)(=O)c4cccs4)CC3)n2)c1 | CCC |
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<|startoftext|><L>Nc1ccc([N+](=O)[O-])cc1C(=O)<mask_1:5>1CCCO1<mask_1:5> | 1 | 28 | 5 | N | 5 | Nc1ccc([N+](=O)[O-])cc1C(=O)[C@H]1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | [C@H] |
<|startoftext|><L>N<mask_1:5>1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1<mask_1:5> | 1 | 1 | 5 | c | 5 | N#CCOc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | #CCOc |
<|startoftext|><L>Nc1ccc([N+](=O)[O-])<mask_1:5>C(=O)N1CCCO1<mask_1:5> | 3 | 20 | 5 | cc1 | 5 | Nc1ccc([N+](=O)[O-])cc1OCC(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | cc1OC |
<|startoftext|><L>N<mask_1:4>([N+](=O)[O-])cc1C(=O)N1CCCO1<mask_1:4> | 5 | 1 | 4 | c1ccc | 4 | Nc1sc([N+](=O)[O-])cc1C(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | c1sc |
<|startoftext|><L>Nc1c<mask_1:3>+](=O)[O-])cc1C(=O)N1CCCO1<mask_1:3> | 5 | 4 | 3 | cc([N | 3 | Nc1c([N+](=O)[O-])cc1C(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | ([N |
<|startoftext|><L>Nc1ccc([N+](=O)[O-])cc1C(=O)N1<mask_1:2>1<mask_1:2> | 4 | 30 | 2 | CCCO | 2 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CC1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | CC |
<|startoftext|><L>Nc1ccc<mask_1:3>[N+](=O)[O-])cc1C(=O)N1CCCO1<mask_1:3> | 1 | 6 | 3 | ( | 3 | Nc1ccc(SC[N+](=O)[O-])cc1C(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | (SC |
<|startoftext|><L>Nc1ccc([N+](=O)[O-])cc1C(=O<mask_1:5>N1CCCO1<mask_1:5> | 1 | 27 | 5 | ) | 5 | Nc1ccc([N+](=O)[O-])cc1C(=O)NCCCN1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | )NCCC |
<|startoftext|><L><mask_1:3>cc([N+](=O)[O-])cc1C(=O)N1CCCO1<mask_1:3> | 4 | 0 | 3 | Nc1c | 3 | Cn1cc([N+](=O)[O-])cc1C(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | Cn1 |
<|startoftext|><L>Nc1ccc([N+](=O)[O<mask_1:2>cc1C(=O)N1CCCO1<mask_1:2> | 3 | 17 | 2 | -]) | 3 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | Nc1ccc([N+](=O)[O-])cc1C(=O)N1CCCO1 | -]) |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]<mask_1:3>CCN2C(=O)CC2CCCC2)n1<mask_1:3> | 2 | 34 | 3 | 2C | 3 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | 2CC |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2<mask_1:5>C2)n1<mask_1:5> | 3 | 48 | 5 | CCC | 5 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2=CCCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | =CCCC |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)<mask_1:6>)c([C@H]2CCCN2C(=O)CC2CCCC2)n1<mask_1:6> | 5 | 21 | 6 | F)cc2 | 6 | Nc1ncc(-c2ccc(C(F)(F)F)cc2F)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | F)cc2F |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)<mask_1:2>cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1<mask_1:2> | 5 | 18 | 2 | (F)F) | 2 | Nc1ncc(-c2ccc(C(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | F) |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)F)<mask_1:5>c2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1<mask_1:5> | 1 | 23 | 5 | c | 5 | Nc1ncc(-c2ccc(C(F)(F)F)c(Cl)c2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | c(Cl) |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)F)cc2)c(<mask_1:2>]2CCCN2C(=O)CC2CCCC2)n1<mask_1:2> | 4 | 29 | 2 | [C@H | 2 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([n]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | [n |
<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CC<mask_1:2>n1<mask_1:2> | 4 | 50 | 2 | CC2) | 2 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | 2) |
<|startoftext|><L><mask_1:5>Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1<mask_1:5> | 0 | 0 | 5 | 5 | CC(C)Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | CC(C) |
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<|startoftext|><L>Nc1ncc(-c2ccc(C(F)(F)F)cc2<mask_1:2>)c([C@H]2CCCN2C(=O)CC2CCCC2)n1<mask_1:2> | 0 | 26 | 2 | 2 | Nc1ncc(-c2ccc(C(F)(F)F)cc2Cl)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Cl |
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<|startoftext|><L>Nc1ncc(-c2ccc(C<mask_1:4>F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1<mask_1:4> | 1 | 15 | 4 | ( | 4 | Nc1ncc(-c2ccc(COCC(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | Nc1ncc(-c2ccc(C(F)(F)F)cc2)c([C@H]2CCCN2C(=O)CC2CCCC2)n1 | OCC( |
<|startoftext|><L>NC[C@@]<mask_1:3>@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:3> | 6 | 7 | 3 | 1(N)[C | 3 | NC[C@@]1[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | 1[C |
<|startoftext|><L>NC[C@@]1(N)[C@H](S(=O)(=O)c<mask_1:2>ccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:2> | 3 | 27 | 2 | 2cc | 2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2sccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | 2s |
<|startoftext|><L>NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)<mask_1:5>1c1ccc2c(c1)OCO2<mask_1:5> | 6 | 35 | 5 | [C@@H] | 5 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | [C@H] |
<|startoftext|><L>NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]<mask_1:4>c1ccc2c(c1)OCO2<mask_1:4> | 1 | 41 | 4 | 1 | 4 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1COCc1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | 1COC |
<|startoftext|><L>NC[C@@]1(N)[C@H](S(=O)(=O<mask_1:8>ccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:8> | 5 | 25 | 8 | )c2cc | 8 | NC[C@@]1(N)[C@H](S(=O)(=O)c2cc(F)ccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | )c2cc(F) |
<|startoftext|><L>NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2<mask_1:3>H]1c1ccc2c(c1)OCO2<mask_1:3> | 5 | 34 | 3 | )[C@@ | 3 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[CH]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | )[C |
<|startoftext|><L>NC[C@@]1(N)[<mask_1:5>](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:5> | 3 | 12 | 5 | C@H | 4 | NC[C@@]1(N)[C@@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | C@@H |
<|startoftext|><L>NC[C@<mask_1:6>(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:6> | 3 | 5 | 6 | @]1 | 6 | NC[C@@H]1OC(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | @H]1OC |
<|startoftext|><L>NC[C@@<mask_1:6>)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:6> | 4 | 6 | 6 | ]1(N | 6 | NC[C@@]1(C#N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | ]1(C#N |
<|startoftext|><L>NC[C<mask_1:7>1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2<mask_1:7> | 3 | 4 | 7 | @@] | 7 | NC[C@H](O)C1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | NC[C@@]1(N)[C@H](S(=O)(=O)c2ccccc2)[C@@H]1c1ccc2c(c1)OCO2 | @H](O)C |
<|startoftext|><L>COC(=O<mask_1:2>1ccc(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:2> | 3 | 6 | 2 | )Cc | 2 | COC(=O)c1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | )c |
<|startoftext|><L>COC(<mask_1:3>c1ccc(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:3> | 4 | 4 | 3 | =O)C | 3 | COC(=O)c1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | =O) |
<|startoftext|><L>COC(=O)Cc1c<mask_1:6>Cc2nc3ccccc3c3ccccc23)cc1<mask_1:6> | 4 | 11 | 6 | cc(O | 6 | COC(=O)Cc1ccc(CNCCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | cc(CNC |
<|startoftext|><L>CO<mask_1:6>)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:6> | 4 | 2 | 6 | C(=O | 6 | COCCN(CC)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | CCN(CC |
<|startoftext|><L>COC<mask_1:2>Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:2> | 4 | 3 | 2 | (=O) | 2 | COCCNCc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | CN |
<|startoftext|><L>COC(=O)Cc1ccc(OC<mask_1:4>cccc3c3ccccc23)cc1<mask_1:4> | 6 | 16 | 4 | c2nc3c | 4 | COC(=O)Cc1ccc(OCc2c3cccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | c2c3 |
<|startoftext|><L>COC<mask_1:1>Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:1> | 4 | 3 | 1 | (=O) | 1 | COCCCc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | C |
<|startoftext|><L>COC(=O)C<mask_1:3>(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:3> | 5 | 8 | 3 | c1ccc | 3 | COC(=O)C1cc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | 1cc |
<|startoftext|><L><mask_1:4>OC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1<mask_1:4> | 1 | 0 | 4 | C | 4 | CCCCOC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | CCCC |
<|startoftext|><L>COC(=O)Cc1ccc(OCc2nc3ccccc3c<mask_1:6>cc23)cc1<mask_1:6> | 4 | 28 | 6 | 3ccc | 6 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3[nH]ncc23)cc1 | COC(=O)Cc1ccc(OCc2nc3ccccc3c3ccccc23)cc1 | 3[nH]n |
<|startoftext|><L>Cn1cncc1-c1cnc<mask_1:6>@H]2CCCN(c3ncccn3)C2)n1<mask_1:6> | 5 | 14 | 6 | c(C[C | 6 | Cn1cncc1-c1cncc(CC[C@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | c(CC[C |
<|startoftext|><L>Cn1cncc1-c1cnc<mask_1:4>@H]2CCCN(c3ncccn3)C2)n1<mask_1:4> | 5 | 14 | 4 | c(C[C | 4 | Cn1cncc1-c1cncc([C@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | c([C |
<|startoftext|><L>Cn1cncc1-c1cncc(C[C@H<mask_1:4>N(c3ncccn3)C2)n1<mask_1:4> | 5 | 21 | 4 | ]2CCC | 4 | Cn1cncc1-c1cncc(C[C@H]2CCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | ]2CC |
<|startoftext|><L>Cn1cncc1-c1cncc(C<mask_1:5>]2CCCN(c3ncccn3)C2)n1<mask_1:5> | 4 | 17 | 5 | [C@H | 5 | Cn1cncc1-c1cncc(C[C@@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | [C@@H |
<|startoftext|><L>Cn1cncc1-c1cncc(C[C<mask_1:3>]2CCCN(c3ncccn3)C2)n1<mask_1:3> | 2 | 19 | 3 | @H | 3 | Cn1cncc1-c1cncc(C[C@@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | @@H |
<|startoftext|><L>Cn1cncc1-c1cncc(C[C@H]2<mask_1:5>3ncccn3)C2)n1<mask_1:5> | 6 | 23 | 5 | CCCN(c | 5 | Cn1cncc1-c1cncc(C[C@H]2CCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | CCN(c |
<|startoftext|><L>Cn1cncc1-<mask_1:2>ncc(C[C@H]2CCCN(c3ncccn3)C2)n1<mask_1:2> | 3 | 9 | 2 | c1c | 2 | Cn1cncc1-n1ncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | n1 |
<|startoftext|><L>Cn1cncc1-c1cn<mask_1:4>(C[C@H]2CCCN(c3ncccn3)C2)n1<mask_1:4> | 2 | 13 | 4 | cc | 4 | Cn1cncc1-c1cn(C)c(C[C@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | (C)c |
<|startoftext|><L>Cn1<mask_1:6>1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1<mask_1:6> | 4 | 3 | 6 | cncc | 6 | Cn1[nH]cc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | [nH]cc |
<|startoftext|><L>Cn1cncc1-c1cncc(C[C@H]2CC<mask_1:6>c3ncccn3)C2)n1<mask_1:6> | 3 | 25 | 6 | CN( | 6 | Cn1cncc1-c1cncc(C[C@H]2CCN(CCCNc3ncccn3)C2)n1 | Cn1cncc1-c1cncc(C[C@H]2CCCN(c3ncccn3)C2)n1 | N(CCCN |
<|startoftext|><L>COCCNC(=O)<mask_1:5>H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:5> | 3 | 10 | 5 | [C@ | 5 | COCCNC(=O)C[C@@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | C[C@@ |
<|startoftext|><L>CO<mask_1:6>(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:6> | 4 | 2 | 6 | CCNC | 6 | COC(=O)C(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | C(=O)C |
<|startoftext|><L>COCCN<mask_1:5>C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:5> | 6 | 5 | 5 | C(=O)[ | 5 | COCCN(C)C[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | (C)C[ |
<|startoftext|><L>C<mask_1:5>NC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:5> | 3 | 1 | 5 | OCC | 5 | CC(C)CNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | C(C)C |
<|startoftext|><L>COCCNC(=O<mask_1:3>[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:3> | 1 | 9 | 3 | ) | 3 | COCCNC(=O)CS[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | )CS |
<|startoftext|><L>COCCNC(=O)[C@H](C<mask_1:2>c1ccc2c(c1)n(C)c(=O)n2C<mask_1:2> | 4 | 17 | 2 | #N)C | 2 | COCCNC(=O)[C@H](C)Sc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | )S |
<|startoftext|><L>COCCNC(=O)[C@H](<mask_1:5>N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:5> | 2 | 16 | 5 | C# | 5 | COCCNC(=O)[C@H](C)N(CN)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | C)N(C |
<|startoftext|><L>COCCNC(=O)<mask_1:4>C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:4> | 6 | 10 | 4 | [C@H]( | 4 | COCCNC(=O)CN(CC#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | CN(C |
<|startoftext|><L>C<mask_1:1>=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:1> | 6 | 1 | 1 | OCCNC( | 1 | C(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | ( |
<|startoftext|><L><mask_1:5>COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C<mask_1:5> | 0 | 0 | 5 | 5 | CC(C)COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | COCCNC(=O)[C@H](C#N)Cc1ccc2c(c1)n(C)c(=O)n2C | CC(C) |
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<|startoftext|><L>Cc1cc(NC<mask_1:3>Cn2nnn(-c3ccccc3Cl)c2=O)no1<mask_1:3> | 4 | 8 | 3 | (=O) | 3 | Cc1cc(NCCCCCn2nnn(-c3ccccc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | CCC |
<|startoftext|><L>Cc1cc(NC(=O)Cn2nnn(-c3ccccc<mask_1:3>c2=O)no1<mask_1:3> | 4 | 27 | 3 | 3Cl) | 3 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3C)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | 3C) |
<|startoftext|><L>Cc1cc(NC(=O)Cn2nnn(-c3ccc<mask_1:5>3Cl)c2=O)no1<mask_1:5> | 2 | 25 | 5 | cc | 5 | Cc1cc(NC(=O)Cn2nnn(-c3ccc(F)cc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | (F)cc |
<|startoftext|><L>Cc1cc(NC(=O)Cn2nnn(-c3cc<mask_1:4>ccc3Cl)c2=O)no1<mask_1:4> | 0 | 24 | 4 | 4 | Cc1cc(NC(=O)Cn2nnn(-c3cc(Cl)ccc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | (Cl) |
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<|startoftext|><L><mask_1:5>c1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1<mask_1:5> | 1 | 0 | 5 | C | 5 | CC(C)c1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | CC(C) |
<|startoftext|><L>Cc1cc(NC(=O)Cn2nnn(-c3ccccc3<mask_1:2>c2=O)no1<mask_1:2> | 3 | 28 | 2 | Cl) | 2 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3C)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | C) |
<|startoftext|><L>Cc1cc(NC(=O)<mask_1:5>nn(-c3ccccc3Cl)c2=O)no1<mask_1:5> | 4 | 12 | 5 | Cn2n | 5 | Cc1cc(NC(=O)CCn2nnn(-c3ccccc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | CCn2n |
<|startoftext|><L><mask_1:5>1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1<mask_1:5> | 2 | 0 | 5 | Cc | 5 | CCCSc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | CCCSc |
<|startoftext|><L>Cc1cc(NC(=O)Cn2nnn(-c3ccccc<mask_1:4>2=O)no1<mask_1:4> | 5 | 27 | 4 | 3Cl)c | 4 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3F)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | 3F)c |
<|startoftext|><L>Cc1c<mask_1:5>C(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1<mask_1:5> | 3 | 4 | 5 | c(N | 5 | Cc1cc(CCNC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | Cc1cc(NC(=O)Cn2nnn(-c3ccccc3Cl)c2=O)no1 | c(CCN |