11.1: Acylation of Alcohols and Amines 11.2: Formation of Carbon-Carbon Bonds Biocatalysts are turned out to be versatile catalysts for carbon-carbon bond forming and reduction reactions in organic synthesis. Carbon-carbon bond formation belongs to the heart of organic synthesis. The biocatalyzed route provides effective tool for the construction of carbon-carbon with excellent enantioselectivity. 11.3: Reduction Reactions The enantioselective reduction of C=X double bonds (X = O, NR, C) to C-XH single bonds plays a major role in asymmetric synthesis. 11.4: Enantioselective Oxidations 11.5: Problems and Reference