A 2004-2005 anime created by [[Sunrise (company)|Sunrise]], directed by Masakazu Obara and written by Hiroyuki Yoshino.

h4. Characters

h5. HiME 
* [[Tokiha Mai]]
* [[Kuga Natsuki]]
* [[Minagi Mikoto]]
* [[Fujino Shizuru]]
* [[Okuzaki Akira]]
* [[Yuuki Nao]]
* [[Sugiura Midori]]
* [[Suzushiro Haruka]]
* [[Kikukawa Yukino]]
* [[Miyu Greer]]
* [[Higurashi Akane]]
* [[Sanada Yukariko]]

h5. Supporting Characters
* [[Tate Yuuichi]]
* [[Tokiha Takumi]]
* [[Munakata Shiho]]
* [[Homura Nagi]]
* [[Alyssa Searrs]]
* [[Himeno Fumi]]
* [[Kanzaki Reito]]
* [[Harada Chie]]
* [[Kurauchi Kazuya]]

h5. Tertiary Characters
* [[Ishigami Wataru]]
* [[Oota Yayoi]]
* [[Sagisawa Youko]]
* [[Arika Yumemiya]]
* [[Chun Mei]]

h4. Spin-offs
* [[My-Otome]]
* [[My-Otome Zwei]]
* [[My-Otome S.ifr]]
* [[My-HiME Rhapsody: Neko-hime Blog]]
舞-HiME