comment: >
  
  First thought is this is potentially amazing, next is are the antivaxers going to be all over this too?
context: As someone who has worked for years in neruology: Here's to hoping that this is available to the general population as soon as possible. >
  
  I believe mRNA vaccines and Crispr are the future. I believe in the not so distant future, even if it's 20,30, 50 years away, we will be able to edit genes in the womb. And on living people. Everything from cancer, epilepsy, schizophrenia, Alzheimer's Parkinson's, will be a minor inconvenience that people will know if they're predisposed can get it fixed. I love science and medicine. Always wanted to be a doctor, and specialize in neurology. Gonna go the PA route and either work on cardiology or neurology. >
  
  Which would be neat if it were available to everyone for minimal cost. On other hand if its extremely expensive and available for wealthy itll be nothing more than harbinger of new form of genetically modified feudalist dystopia. >
  
  call me pessimistic but that's exactly what I imagine would happen. there's no benefit I can see to making stuff like gene therapy affordable >
  
  Society does change on a generational scale. In 50 years the world may well be a very different place. >
  
  Do you find capitalism to be different now than it was in 1973? >
  
  Yes, at least in America things have gotten much worse for the working class clearly and the rich have gained more power.  But that does not mean the trend will continue 50 years from now.  For all we know unions will rise again as a powerful force. Also globally things are actually much improved for the most impoverished since 1973. One thing I know for sure: giving up isn't a good strategy. >
  
  
  For all we know unions will rise again as a powerful force.
  
  I'm seeing a bunch of unions for game developers popping up here and there, hoping they do some good >
  
  The funny thing is people think that unions are somehow anticapitalist. I see them just as companies that advocate for their members. Companies within companies. It's actually how life evolved with cells living inside of other cells, which eventually gave rise to the cellular components all working together. No reason to think that we can't evolve cooperative systems on a global scale. Give it time. >
  
  The current accepted theory is that some cells weren't able to breakdown some other cell (notably bacteria), and the now ingested bacteria also wasn't a detriment to the larger cell. A Prokaryotic cell did not just begin to evolve organelles from our current understanding.
  Eventually the inner cell(s) began to specialize, leading to Eukaryotic cells.
  It's called endosymbiosis.
  To your example, it'd be more akin to a union forming from a company that was bought out by another. >
  
  well, that's both wonderful and very sad.  Just past 2 yrs since I lost a lifelong friend who needed a couple more decades of being amazing.  Diagnosis to death in less than 4 months.
  Here's to all the other amazing people this will save. >
  
  Lost my dad in Sept.  More like 3 months for him.   Surgery had no effect. >
  
  Same.  and it was more like 3 now that I actually count.  Seemed endless.  The horrible thing is the wee bit of hope the surgery gives, which you don't want to crush even when you know it's not going to change anything.  Strong family history = we knew what was happening, and how unstoppable it was. >
  
  We were just hoping for a little more time so we could all do one last trip as a family.  
  But he never left the hospital once admitted. >
  
  I’m so sorry, it’s a fucking awful thing. Lost my dad to glioblastoma in July, and in many ways, he was one of the lucky ones, the surgery to remove the initial tumor was pretty successful, and he lived for just over a year from the initial diagnosis.
  But even so, it was just brutal seeing his mental and physical faculties being stripped away one by one, and the seemingly relentless nature of the cancer. Hopeful that this treatment will be able to change that in future. >
  
  I am not sure if it was a blessing he went so fast in my dad's case.
  My mom was so worried about taking care of him and the costs. 
  I was lucky to say goodbye before he had lost his mental faculties and then just weeks later he was gone. 
  Anything that would give some hope or prevent would be a godsend. >
  
  I'm sure your dad really really loved you bro, please keep your head up as much as possible >
  
  Thanks.  He had hope at the time, and when i left it was really see you later and not goodbye.
  He had improved a bit and was still my dad when i had to fly 3000 miles away.
  He was a very stoic man and never said he loved me in so many words.
  But when i walked into his hospital room, a tear fell. >
  
  It hasn’t been through human trials, so it‘s not approved yet. >
  
  There should be a subreddit that keeps track of all of these medicines. I want to know when human trials occur and how they work. >
  
  Keeping Clinicaltrials.gov updated is an enormous task: Every study team has to individually enter their study data and keep it current. There are currently over 150,000 active studies in the US alone. 
  I don’t see how migrating it to a subreddit would meaningfully improve access enough to make such an incredible (and neverending) lift worth it. >
  
  The point of a subreddit would be to give a spotlight to the most relevant or promising studies, with potentially large impacts. Dropping a link to 150,000 active studies doesn't really help much, because the layman can't just look it over and figure out which ones are actually at a point where they're going to help anyone in the next 30 years. 
  Not to mention the fact that a bunch of that is going to be like, cures for warts on your toe or whatever. 
  I assume what this commenter was looking for is a subreddit that posts curated information to help the average idiots like myself know when big breakthroughs are happening, not just "a trial on ants yielded promising data about a potential eczema cream formula that could reduce costs by up to 9%" >
  
  r/Science? >
  
  I wish this was found 17 years ago to save my first wife >
  
  I'm sorry about your wife, but I hope you're ok. >
  
  What a horrible disgusting and insensitive thing to say. >
  
  Oh God what'd they say? >
  
  I have an old HS friend currently in hospice with Brain cancer.
  She’s 21. I don’t think she’ll make it past the end of the month. But stuff like this gives me hope.
  Cancer is a bitch, but every day we make new and impressive strives forward.
  My hopes are that one day, this terrible disease is finally made history. >
  
  This sucks. I kind of hope your friend doesn't hear about this, because I can't help but think that'd be horrible to realize a way to stop this is coming but it won't be soon enough. >
  
  I completely agree. She’s made her peace, she’s fully aware of her reality. 
  Just wish this news/treatment could’ve arrived way back when, but so would everyone who ever faced hardships, you know? >
  
  Cgp Grey has a good video about how unnecessary death is, and the sooner we commit to the moonshot of cancelling death, the more people we can save. >
  
  For real? Can you link this please? >
  
  Fable of the Dragon-Tyrant >
  
  I hope this works out in the end.  It looks very promising.  My father died 14.5 years ago from this.  He was diagnosed the day after he retired.  While it would of course not bring him back, it would make it so others didn't lose people to something so fucking horrible.
  I miss you Dad, I love you. >
  
  This makes me cry. Tears of hope that someday soon glioblastoma won’t take anymore loved ones, tears of sadness because 17 years ago my brother never had a chance of beating it. >
  
  I know you pain. My wife's mother died two years ago from it and it was a rough time for everyone involved so my hope is others don't have to suffer from this one day. >
  
  A treatment for GBL. Amazing. >
  
  there should be a blanket ban on reddit of any "cancer vaccine" and "cancer treatment" hype articles done by the marketing teams of startups,pharma corps and unis to raise stock price until it's actually confirmed that it's a more general cancer vaccine. The title at least should be more accurate about what the vaccine targets and less hypy.
  Cancer is not a disease. It's an umbrella term for a group of diseases that can be summed up as "genes gone wild which make cells replicate uncontrollably". In general no two cancers are the same since the genetic mutations of the cancer of person A are not the same as the genetic mutations of person B and hence a vaccine that works on person A might not work on person B. Some cancer tumours in the same person have more than one genomic mutation so the same person might need two types of vaccines for the same tumour.
  What happens sometimes is that some mutations are common among multiple cancer patients and that is when the vaccines come in. The first vaccines in history I think were done on certain types of cervical cancer. 
  Actual cancer scientists have known since like the 70s-80s that the only "cure for cancer" is basically individualized DNA treatment. You take samples of your own cancer and develop a vaccine/treamtent for your individual type of cancer. That hasn't been dicovered so far but that is the future and a lot of diseases such as aging(parkinsons, alzheimers, osteoporosis etc)will probably used some sort of individualized gene therapy to be treated. The small downside from my pov is that a treatment for cancer will prob be very useful as an individualized bioweapon too since if you can create something that destroys individual cancer cell based on strands of genome you will be able to target any cell in the body based on strands of genome(keep in mind cancer cells are our own cells they have just gone insane. They are not foreign cells like it happens in malaria or ebola for example). But that is a small downside compared to the actual advantages. >
  
  I can understand the concept of " let's find a cure for cancer", but ya, way more complicated than that. 
  For example, when people talk about brain cancer they are usually referring to glioblastoma because it's such a fucking terrible death sentence. But there are more than one kind of brain cancer. I mean, just in the gliomas alone there are dozens.
  A pet peeve of mine is most brain cancer treatment articles are talking about glioblastoma without actually saying glioblastoma. I guess it bugs me because I also have brain cancer but a less aggressive type (oligodendroglioma) so it doesn't get much research. Don't get me wrong, research should ABSOLUTELY be focused on GBM I'm just tired of getting my hopes up every time I see an article. In the words of my neuro-oncologist, "You have the BEST kind of brain cancer." Best in the sense that you get years and years if not a couple decades. So I guess I should be greatfull for that. Doesn't mean I like it there though. 
  And for all those that will potentially ask, I'm doing well. I'm 6 years in and have had surgery, chemo, and radiation. It's been stable since 2019. >
  
  My husband is currently treating with this kind of diagnosis. The “best kind,” but fuuuuuck it’s still brain cancer. It’s so tough. I’m glad to hear you’re stable. 
  Same feeling on the articles—there’s so little known by the general public about brain cancer that it’s truly hard for me to be able to know what to read because the different types are wildly different, but anything less than very particular scientific studies don’t make the distinctions. Luckily, we have a good NO to rely on, but man I’d like to be able to do more than just twiddle my thumbs between MRIs. I’d like to be able to ask intelligent questions. 
  Best of luck on your continuing treatment. >
  
  Thanks, and best of luck to you as well!!
  Best thing I'm doing for myself right now is continuing with therapy for my depression. 
  If I have 10+ years in front of me I'd rather live it happy and motivated enough to do healthy things for myself and enjoy friends and family.
  As an aside, if he has an oligodendroglioma, there's an organization out there named Oligo Nation that is pushing to advance treatments for this particular cancer. 
  Might not help much, but my Amazon smile account is linked to them. >
  
  Lost my mother to different cancer and sister currently battling stage 3. Im rooting for every progress on cures science gives us. We sometimes never know who or the teams doing such hardwork that creates them.
  I say, Thank you, thank you for giving others a chance were others didnt. So that others get a fighting chance, I hope in the future we have something for all cancers, so we never lose someone to something so cruel and silent until its too late. >
  
  My mom just passed from gbm after 21months. However she refused the covid vaccine because of its mRNA basis. I wonder if she would’ve refused this as well if available. She was a nurse her whole life and let propaganda change everything >
  
  But it’s plancer! It’s an experimental jab! I’m no sheeeeeep! 
  Kindly reporting comments from future twitter. >
  
  There should be an “in mice” flair for these posts >
  
  Holy moly!! A cure and prevention for glioblastoma? This is so beautiful. I hope it works. >
  
  So am I, my cousin died of this. >
  
  It's been a real shitty day but this news is so good that I can't help but smile. >
  
  A friend of mine lost both of her kids last year due to brain cancer. They tried to beat it for four years. They were 8 and 10, her only children, a boy and girl. >
  
  Jesus! I'm so sorry to hear that! That's awful 😞 >
  
  It is definitely a tragedy. They had amazing support and medical care, yet it was inevitable. The little boy passed two days before Christmas. >
  
  I lost both my mom and my aunt to brain and lung cancer 28 days apart. I watched as it turned them into complete zombies at the end. If this works and can be released I will gladly sign up for it. After watching what they went through I wouldn't want to suffer that, nor see anyone else's loved ones suffer through it. >
  
  Whoever comes up with a true vaccine will have performed a miracle.  I hope I get to see it in my lifetime. >
  
  …in a mouse.
  Cool stuff, but lots of stuff works in mice and fails in humans. >
  
  It’s a good time to be a mouse. >
  
  Now just make sure it doesn't turn people into creatures of the night, and we're golden. >
  
  I read that as “creatures of the right” and thought: yeah, that would be terrifying >
  
  ”We’re going to make cancer great again” 👌 >
  
  Thank you u/NeverEnoughBoobies for passing along this truly amazing news. I hope it's available for everyone very soon! >
  
  Glioblastoma has been running roughshod over my life since I first heard of it in 2001 when my friends brother was diagnosed with it.  It killed 3 parents in my my son's grade one year and my husband uncle passed away from it a few years back.  Recent other losses have put me into a very nihilistic place where I feel no one is safe and what's the point of caring about anything.
  This actually gives me some hope. >
  
  
  stem cell therapy 
  
  That's going to piss of the crayon eaters. >
  
  Crayon eaters are always pissed off, there's no point in trying to appease them. >
  
  This is bitter sweet. My mom passed away from brain cancer in October, but I hope that this can help prevent anyone else from going through what I went through. >
  
  Anti vaxxers bout to start rethinking their stance right now… >
  
  UHM yes please and immediately ad a survivor of glioblastoma and knowing it can and will eventually return this is huge for me and other people in my situation >
  
  My dad checked out from lung cancer 14 years ago. Blessed to all others who now suffer from cancer and God speed this vaccine will come to fruition and be their savior. >
  
  Can't wait to never hear about this again. >
  
  Heh, yeah, in the meantime, I'll just peruse some climate doomsday articles! >
  
  in mice
  99% of research phase drugs fail to get approved. >
  
  Nah, I'll just drink some bleach and inject some horse dewormer into my ear. I'm good. >
  
  How long before the vaccine
  Is available to the public? >
  
  Years, they only have results from animal tests right now. >
  
  This makes me so happy. I lost my father to cancer (small cell lung cancer that spread to his brain, I literally watched him forget all of his family), and I hope sometime soon, cancer will be a thing of the past.
  FUCK CANCER!!! >
  
  Isn't this the beginning of a zombie invasion in like 20 different movies? I'm joking, of course. It's awesome (and very welcome) if it ends up working well and becoming accessible for most people. Cancer is terrible and brain cancer has to be one of the worst. >
  
  My former CEO (Dan Case) died of brain cancer.  He was such an awesome person, would literally come down to my desk and watch early internet video clips and cartoons with me (soxmas was his favorite lol).  I have so many fond memories of working with him, wish I had more.  Brain cancer is a bitch.  This news is bittersweet for those of us who have lost friends and loved ones, but I’m super stoked for all those who finally have hope.
  Dan Case >
  
  My grandmother died 2 years ago at 67 from glioblastoma. I'm thankful that in the future, other families will be spared the horror of that sickness. Well done science. >
  
  As a pharma person, it's v difficult to get this from POC to phase 3, but hoping it'll work....we had a GBM trial fail recently. Brain is notoriously difficult... >
  
  Yo so I’ve got brain cancer, can someone hook me up >
  
  My aunt died of brain cancer last year. Damn. :( Just a year too late, Aunt Karen.
  Yes, her name was Karen, and yes, the name was apropos, lol. >
  
  Great, then make it for cats! >
  
  Sorry but not even a cancer vaccine could fix that movie >
  
  Release the Brain Tumor cut. >
  
  It's like the original, except the unsightly holes are in their heads now.