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  Oh God Topomax is awful.  I have been on that in the past and it really does affect your memory and cognition.
context: I was on a migraine medication that is also popular for weight loss. I did lose a lot of weight, which wasn't bad but I also would sometimes not feel my nose, had weird out of body feelings sometimes and boughts of nausea. Finally stopped taking it because I realized it really did live up to its nickname dopamax.