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every country would need to sign off on having one pilot, it wouldn't matter if the FAA lost its mind and said "sure, one pilot, what could go wrong," because US airlines don't make any money if they can't fly to other countries.

That's easy enough to work around. They just fly one pilot domestically and two for international flights. Realistically they would need two pilots for long hauls anyways. Most of their flights, by far, are domestic so it's still a win for the airlines.
An absolute YIKES! after watching that. >

Get the kid, get the shit, we are gettin the fuck out a here! >

Yeah, I thought that video did a lot better job of getting the sentiment across... >

Just remember, railroads are actively trying to take the conductor out of the cab and effectively cut crew size on trains from 2 to 1. The conductor is essentially the first responder to all derailments and grade crossing accidents and carries a hard copy sequenced list of all rail cars in a train and their commodities.
They’ve drastically cut car inspectors and track employees as well over the last 5-7 years.
Train size and weight has doubled in that same time frame causing added stress on infrastructure and rolling stock. 
Keep in mind, we are doing our best out here to move products safely through your town without the proper rest or equipment to do it safely. >

Just like airlines are attempting to have just 1 pilot in the cockpit.
When profit is the # 1 objective corporations know no bounds. Anything in the way is expendable. >

Yeah, the day they go down to one pilot is the day I stop flying. Planes are great and safe ... but having a backup (even if not to manage the workload) is important. >

I give it a 40% chance it happens in the next 40 years, and it's not going to happen in the next 20 years. Not only do the aircraft manufacturers need to manage a computer capable of replacing the workload of the first officer in an emergency situation, they also need to gain the public trust, and we're at least a couple decades away from that, and that's without another 737-MAX style fiasco. 
We live in a connected world, so every country would need to sign off on having one pilot, it wouldn't matter if the FAA lost its mind and said "sure, one pilot, what could go wrong," because US airlines don't make any money if they can't fly to other countries. The downside of this is you end up stuck with silly outdated rules like "turn off all of your cell phones" just because one country won't agree to move past it.