I always find it difficult to understand well known opening positions with the colors inverted. If I had this position with Black a tempo up, I'd be feeling very comfortable. But looking at White's position, the chances of an advantage don't seem promising to me. It's probably all a matter of perspective and expectation.
1. c2c4  1... e7e5  2. b1c3  2... g8f6  3. g1f3  3... b8c6  4. d2d3 [%c_effect d3;square;d3;type;Interesting;persistent;true] An interesting choice by Giri, leading to a position without much forced theory, a Sicilian Defense with inverted colors. 4... d7d5  5. c4d5 