Once my friend GM Ivan Morovic told me that against 1.c4 Black's only possible moves are either 1...e5 or 1...c5. I must confess that I never really understood what he meant with that.
1. c2c4 This is clearly the best first move available for White, with due respect to Fischer's 1.e4 \"best by test\" fans. But maybe I'm a little biased.