Najdorf players have the old dilemma of whether to advance the pawn to e5, as Fischer liked, or to e6, as Kasparov prefered. If you like more alternative paths it's possible to play the \"Dragondorf\" with 6...g6, the classic 6...Nc6, or even 6...b5.
1. e2e4  1... c7c5  2. g1f3  2... d7d6  3. d2d4  3... c5d4  4. f3d4  4... g8f6  5. b1c3  5... a7a6  6. h2h3 One of the options with the best reputation against the Najdorf.