Human: What is the difference between a monotheistic and polytheistic religion? Assistant: 
The main difference between a monotheistic and polytheistic religion is the belief in the existence of a single god versus multiple gods. In monotheistic religions, such as Christianity, Judaism, and Islam, the single god is believed to be the creator of all things, whereas in polytheistic religions, such as Hinduism, there are multiple deities that form a pantheon of gods.