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A 60-year - old white man with chronic bronchitis was noted to develop acute respiratory failure and metabolic acidosis four days after being started on methazolamide ( Neptazane ) for an ophthalmologic problem .
 adverse effect: acute respiratory failure, methazolamide; adverse effect: acute respiratory failure, Neptazane; adverse effect: metabolic acidosis, methazolamide; adverse effect: metabolic acidosis, Neptazane
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: acute respiratory failure, methazolamide; adverse effect: acute respiratory failure, Neptazane; adverse effect: metabolic acidosis, methazolamide; adverse effect: metabolic acidosis, Neptazane