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Our report suggested that CBDCA hypersensitivity was correlated with the total dose of previously administered platinum agents and that CBDCA should be excluded in patients who have received multiple platinum - based chemotherapy , even in platinum - sensitive cases , because CBDCA hypersensitivity can occur even with low - dose CBDCA administration .
 adverse effect: hypersensitivity, CBDCA; adverse effect: hypersensitivity, CBDCA; adverse effect: hypersensitivity, CBDCA; adverse effect: hypersensitivity, CBDCA
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: hypersensitivity, CBDCA; adverse effect: hypersensitivity, CBDCA; adverse effect: hypersensitivity, CBDCA; adverse effect: hypersensitivity, CBDCA