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For patients who suffer from osteogenic sarcoma and have anaphylactic reactions to MTX , this desensitization protocol will allow these patients to continue with needed therapeutic or palliative chemotherapy .
 adverse effect: anaphylactic reactions, MTX
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: anaphylactic reactions, MTX