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Despite a hematologic response in all 3 patients , none of them achieved cytogenetic remission , and all progressed to blast crisis at 7 to 10 months of imatinib therapy .
 adverse effect: blast crisis, imatinib
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: blast crisis, imatinib