351
CONCLUSIONS : This observation of " on - off " risperidone treatment suggests that risperidone may have worsened both psychiatric and physical manifestations of the mitochondrial disorder in this adolescent .
 adverse effect: psychiatric and physical manifestations, risperidone; adverse effect: psychiatric and physical manifestations, risperidone
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: psychiatric and physical manifestations, risperidone; adverse effect: psychiatric and physical manifestations, risperidone