11877
PTE also down - regulated the expression of STAT3 target genes , including the anti - apoptotic proteins Bcl - xL and Mcl - 1 , leading to the up - regulation of mitochondrial apoptosis pathway - related proteins ( Bax , Bak , cytosolic Cytochrome c , and cleaved Caspase3 ) and cyclin - dependent kinase inhibitors such as p21 and p27 .
 Chemical: PTE
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: PTE 
Answer:
 Chemical: PTE