11883
An increase in the intracellular Ca2+ concentration is both necessary and sufficient for Rap1 activation since it was induced by agents that increase intracellular Ca2+ and inhibited by a Ca2+ -chelating agent .
 protein: Rap1
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
 Entities: Rap1 
Answer:
 protein: Rap1