1353
mRNA expression of neural cell adhesion molecule 1 , an adhesion protein participating in the maintenance of islet architecture , decreased in biotin - supplemented islets .
 Chemical: biotin
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: biotin 
Answer:
 Chemical: biotin