4829
Analysis of the ARSA gene in this patient revealed heterozygosity for two new mutant alleles in one allele , deletion of C 447 in exon 2 leads to a frameshift and to a premature stop codon at amino acid position 105 ; in the second allele , a G - - > A transition in exon 5 causes a Gly309 - - > Ser substitution .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
 Entities:  
Answer:
 None