17465
However , repeated administration of high dose JZL184 ( 40 mg / kg ) causes dependence , antinociceptive tolerance , cross - tolerance to the pharmacological effects of cannabinoid receptor agonists , and CB ( 1 ) receptor downregulation and desensitization .
 Chemical: JZL184
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: JZL184 
Answer:
 Chemical: JZL184