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We therefore addressed possible effects of tamoxifen on the generation of cleaved cyclin E and its signal mechanism ( s ) in estrogen - responsive MCF - 7 breast cancer cells that express both G protein - coupled protein ( GPR ) 30 and estrogen receptor alpha ( ER alpha ) .
 Chemical: tamoxifen; Chemical: estrogen; Chemical: estrogen
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: tamoxifen, estrogen, estrogen 
Answer:
 Chemical: tamoxifen; Chemical: estrogen; Chemical: estrogen