2218
Here we report ( 1 ) identification of another mutation , on a haplotype 9 chromosome , which converts codon 65 from isoleucine ( ATT ) to threonine ( ACT ) , ( 2 ) expression analysis of the I65T mutation in COS cells demonstrating 75 % loss of both immunoreactive protein and enzyme activity , and ( 3 ) expression analysis of the most prevalent PKU allele ( M1V ) in eastern Quebec , showing nondetectable levels of PAH protein and activity , a finding compatible with a mutation in the translation initiation codon .
 Disease: PKU
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
 Entities: PKU 
Answer:
 Disease: PKU