22159
Compared with the control group , the astaxanthin - treated groups exhibited downregulated protein expressions of alpha - smooth muscle actin , vimentin , hydroxyproline , and B cell lymphoma / leukemia - 2 as well as upregulated protein expressions of E - cadherin and p53 in vitro and in vivo .
 Chemical: astaxanthin; Chemical: hydroxyproline
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: astaxanthin, hydroxyproline 
Answer:
 Chemical: astaxanthin; Chemical: hydroxyproline