1287
Matrix metalloproteinases 2 and 9 decreased , but the tissue inhibitors of metalloproteinases 1 and 2 did not change .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None