2217
In contrast to mice , the human APOE gene is characterized by three common isoforms APOE epsilon 2 , epsilon 3 , and epsilon 4 that result in different metabolic properties of the apoE isoforms , but it remains controversial whether the APOE polymorphism influences bone traits in humans .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None