11255
Moreover , Acrolein resulted in activation of astrocytes , up - regulation of BACE - 1 in cortex and down - regulation of ADAM - 10 in hippocampus and cortex .
 Chemical: Acrolein
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: Acrolein 
Answer:
 Chemical: Acrolein