458
Acute administration of GRN - 529 ( 0 . 1 - 30 mg / kg p . o . ) had dose - dependent efficacy across a therapeutically relevant battery of animal models , comprising depression ( decreased immobility time in tail suspension and forced swim tests ) and 2 of the co - morbid symptoms overrepresented in TRD , namely anxiety ( attenuation of stress - induced hyperthermia , and increased punished crossings in the four plate test ) and pain ( reversal of hyperalgesia due to sciatic nerve ligation or inflammation ) .
 Chemical: GRN - 529
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: GRN - 529 
Answer:
 Chemical: GRN - 529