1618
Yeast knockout models , and histological and biochemical data from patient heart biopsies or autopsies indicate that the frataxin defect causes a specific iron - sulfur protein deficiency and mitochondrial iron accumulation leading to the pathological changes .
 Disease: iron - sulfur protein deficiency
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
 Entities: iron - sulfur protein deficiency 
Answer:
 Disease: iron - sulfur protein deficiency