12458
Investigation into the mode of action of this class of compounds revealed that , in agreement with previous findings , the cytotoxic effects arise through induction of large acid vacuoles .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None