30113
The antibiotic activity of the strain was maximized by using a dual - stage , multivariate statistical optimization framework based on the response surface methodology considering a lab - scale fermentation process .
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Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None