11439
Current evidence for this type of DNA supercoiling - dependent transcriptional coupling , based largely on the in vivo activities of promoters contained in engineered DNA constructs , suggests that the transcription complex must be physically hindered to generate DNA supercoils and to prevent their diffusion throughout the DNA duplex .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
 Entities:  
Answer:
 None