11022
Reduction of IL-2 production is secondary to the inability to phosphorylate the cAMP response element binding protein , CREB , and induce expression of the immediate early genes such as Fos B that are required to transactivate the IL-2 promoter .
 protein: IL-2; DNA: IL-2 promoter; DNA: immediate early genes; protein: CREB; DNA: Fos B; protein: IL-2; protein: cAMP response element binding protein
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
 Entities: IL-2, IL-2 promoter, immediate early genes, CREB, Fos B, IL-2, cAMP response element binding protein 
Answer:
 protein: IL-2; DNA: IL-2 promoter; DNA: immediate early genes; protein: CREB; DNA: Fos B; protein: IL-2; protein: cAMP response element binding protein