10933
Since both are substrates , co - administration of rivaroxaban and apixaban with strong cytochrome P450 ( CYP ) 3A4 and permeability glycoprotein ( P - gp ) inhibitors and inducers can result in substantial changes in plasma concentrations due to altered clearance rates ; consequently , their concomitant use is contraindicated and caution is required when used concomitantly with strong CYP3A4 and P - gp inducers .
 Chemical: rivaroxaban; Chemical: apixaban
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities: rivaroxaban, apixaban 
Answer:
 Chemical: rivaroxaban; Chemical: apixaban