8143
In this study we have introduced mutations into the corresponding elements of two cox3 promoters and show that while the core element is essential for cox3 promoter activity , upstream element mutations have little or no effect .
 GENE: cox3 promoters; GENE: cox3 promoter
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
 Entities: cox3 promoters, cox3 promoter 
Answer:
 GENE: cox3 promoters; GENE: cox3 promoter