24981
Therefore , treatment with opioids requires a careful individualization of dosage to achieve an appropriate balance of efficacy and adverse effects and , consequently , avoid toxicity , particularly respiratory depression , sedation and for some , cardiac ventricular fibrillations .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None