1415
Within the families with male - to - male disease transmission , alpha increased with the early mean age at diagnosis ( < 65 years , alpha = . 19 , with 1 - LOD support interval . 06 - . 34 ) and the number of affected family members ( five or more family members , alpha = . 15 , with 1 - LOD support interval . 04 - . 28 ) .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
 Entities:  
Answer:
 None