11122
To facilitate manipulation of large genomic sequences , we developed a method of converting Escherichia coli P1 artificial chromosomes ( PACs ) into yeast artificial chromosomes ( YACs ) .
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Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
 Entities:  
Answer:
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