10415
However , in the mid - to - late 1980s , a series of letters to the editor and case reports announced an association between tamoxifen therapy in women with breast cancer and the development of endometrial carcinoma .
 adverse effect: endometrial carcinoma, tamoxifen
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  endometrial carcinoma, tamoxifen 
Answer:
 adverse effect: endometrial carcinoma, tamoxifen