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We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin , and was subsequently given epinephrine by mistake intravenously rather than subcutaneously .
 adverse effect: acute myocardial ischemia, epinephrine; adverse effect: severe allergic reaction, epinephrine; adverse effect: severe allergic reaction, epinephrine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  acute myocardial ischemia, epinephrine; severe allergic reaction, epinephrine; severe allergic reaction, epinephrine 
Answer:
 adverse effect: acute myocardial ischemia, epinephrine; adverse effect: severe allergic reaction, epinephrine; adverse effect: severe allergic reaction, epinephrine