6039
We reported 3 patients who developed acute generalized dystonia and akinetic rigid syndrome following an initial therapy with d - penicillamine 125 - 500 mg daily .
 adverse effect: acute generalized dystonia, d - penicillamine; adverse effect: akinetic rigid syndrome, d - penicillamine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  acute generalized dystonia, d - penicillamine; akinetic rigid syndrome, d - penicillamine 
Answer:
 adverse effect: acute generalized dystonia, d - penicillamine; adverse effect: akinetic rigid syndrome, d - penicillamine