6991
Three patients with niacin - induced visual symptoms had cystoid maculopathy without leakage on fluorescein angiography , and a fourth patient with no fundus abnormality experienced cessation of visual symptoms upon discontinuation of niacin .
 adverse effect: cystoid maculopathy, niacin; adverse effect: visual symptoms, niacin; adverse effect: visual symptoms, niacin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  cystoid maculopathy, niacin; visual symptoms, niacin; visual symptoms, niacin 
Answer:
 adverse effect: cystoid maculopathy, niacin; adverse effect: visual symptoms, niacin; adverse effect: visual symptoms, niacin