4084
A 40-year - old man with a long standing history of rheumatoid arthritis was treated with MTX over a 6 month period and developed an overwhelming hepatic necrosis .
 adverse effect: overwhelming hepatic necrosis, MTX
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  overwhelming hepatic necrosis, MTX 
Answer:
 adverse effect: overwhelming hepatic necrosis, MTX