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This case and a review of the literature show the severe and unpredictable nature of ethambutol toxicity and its potential for irreversible vision loss despite careful ophthalmologic monitoring .
 adverse effect: ethambutol toxicity, ethambutol; adverse effect: vision loss, ethambutol
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  ethambutol toxicity, ethambutol; vision loss, ethambutol 
Answer:
 adverse effect: ethambutol toxicity, ethambutol; adverse effect: vision loss, ethambutol