9568
We suggest that nicotinic acid was the cause of his liver disease , that this case is of particular note because of the rather short period of therapy before the onset of liver injury and the severity of the hepatic failure , and that the probable increased use of nicotinic acid for serum cholesterol control makes it especially important for physicians and their patients to be alert to the signs of hepatotoxicity .
 adverse effect: hepatotoxicity, nicotinic acid; adverse effect: liver disease, nicotinic acid; adverse effect: liver disease, nicotinic acid
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  hepatotoxicity, nicotinic acid; liver disease, nicotinic acid; liver disease, nicotinic acid 
Answer:
 adverse effect: hepatotoxicity, nicotinic acid; adverse effect: liver disease, nicotinic acid; adverse effect: liver disease, nicotinic acid