6477
CONCLUSIONS : Optic neuritis in combination with other neurological signs , simulating multiple sclerosis , should be included in the list of adverse effects of recombinant and natural interferon alpha administration .
 adverse effect: neurological signs, interferon alpha; adverse effect: Optic neuritis, interferon alpha
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  neurological signs, interferon alpha; Optic neuritis, interferon alpha 
Answer:
 adverse effect: neurological signs, interferon alpha; adverse effect: Optic neuritis, interferon alpha