4063
OBJECTIVE : To report a case of significant hepatic and renal failure with the use of argatroban in a patient with heparin - induced thrombocytopenia ( HIT ) requiring continuous veno - veno hemodialysis ( CVVHD ) .
 adverse effect: hepatic and renal failure, argatroban; adverse effect: thrombocytopenia, heparin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  hepatic and renal failure, argatroban; thrombocytopenia, heparin 
Answer:
 adverse effect: hepatic and renal failure, argatroban; adverse effect: thrombocytopenia, heparin