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One patient developed large intramural esophageal hematoma as a complication of heparin therapy .
 adverse effect: large intramural esophageal hematoma, heparin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  large intramural esophageal hematoma, heparin 
Answer:
 adverse effect: large intramural esophageal hematoma, heparin