12252
Careful follow - up of so - called " self - limited " insulin edema is encouraged , and the early institution of diuretic therapy is advocated in elderly patients to prevent the development of overt cardiac failure .
 adverse effect: edema, insulin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  edema, insulin 
Answer:
 adverse effect: edema, insulin