8902
We now report the first known cancer patient who developed life - threatening complications after treatment with topical 5-FU and was shown subsequently to have profound DPD deficiency .
 adverse effect: life - threatening complications, 5-FU
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  life - threatening complications, 5-FU 
Answer:
 adverse effect: life - threatening complications, 5-FU