13438
We report the case histories of two patients with histologically confirmed adenocarcinoma of the prostate , both of whom had been treated with steroidal anti - androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation , and who subsequently developed femoral head avascular necrosis .
 adverse effect: femoral head avascular necrosis, cyproterone acetate
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  femoral head avascular necrosis, cyproterone acetate 
Answer:
 adverse effect: femoral head avascular necrosis, cyproterone acetate