1649
Hyperkalaemia with renal tubular dysfunction by oral therapy of sulfamethoxazole - trimethoprim ( co - trimoxazole ) is described in 2 elderly Japanese patients with lymphoid malignancy , who developed Pneumocystis carinii pneumonia and improved .
 adverse effect: Hyperkalaemia, co - trimoxazole; adverse effect: Hyperkalaemia, sulfamethoxazole - trimethoprim; adverse effect: renal tubular dysfunction, co - trimoxazole; adverse effect: renal tubular dysfunction, sulfamethoxazole - trimethoprim
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  Hyperkalaemia, co - trimoxazole; Hyperkalaemia, sulfamethoxazole - trimethoprim; renal tubular dysfunction, co - trimoxazole; renal tubular dysfunction, sulfamethoxazole - trimethoprim 
Answer:
 adverse effect: Hyperkalaemia, co - trimoxazole; adverse effect: Hyperkalaemia, sulfamethoxazole - trimethoprim; adverse effect: renal tubular dysfunction, co - trimoxazole; adverse effect: renal tubular dysfunction, sulfamethoxazole - trimethoprim