4849
CONCLUSIONS : This case describes the clinically significant increase of INR in an elderly patient after adding a chemotherapy regimen of levamisole and 5-FU to a previous regimen of warfarin alone .
 adverse effect: increase of INR, 5-FU; adverse effect: increase of INR, levamisole; adverse effect: increase of INR, warfarin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  increase of INR, 5-FU; increase of INR, levamisole; increase of INR, warfarin 
Answer:
 adverse effect: increase of INR, 5-FU; adverse effect: increase of INR, levamisole; adverse effect: increase of INR, warfarin