1532
This severe illness was likely caused by minocycline , and we speculate that minocycline may have acted as a superantigen , causing lymphocyte over - activation and massive cytokine release .
 adverse effect: lymphocyte over - activation, minocycline; adverse effect: massive cytokine release, minocycline; adverse effect: severe illness, minocycline
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  lymphocyte over - activation, minocycline; massive cytokine release, minocycline; severe illness, minocycline 
Answer:
 adverse effect: lymphocyte over - activation, minocycline; adverse effect: massive cytokine release, minocycline; adverse effect: severe illness, minocycline