3908
The former patient had complained once that his visual acuity had decreased after the termination of IFN therapy , and the latter patient complained twice during IFN therapy that his visual acuity had decreased .
 adverse effect: visual acuity had decreased, IFN; adverse effect: visual acuity had decreased, IFN
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  visual acuity had decreased, IFN; visual acuity had decreased, IFN 
Answer:
 adverse effect: visual acuity had decreased, IFN; adverse effect: visual acuity had decreased, IFN