3684
CONCLUSIONS : The increasing prevalence of Type 2 diabetes and its treatment with metformin might result in more cases of lactic acidosis .
 adverse effect: lactic acidosis, metformin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  lactic acidosis, metformin 
Answer:
 adverse effect: lactic acidosis, metformin