3286
We describe the clinical response , as determined by increases in total Hb and decreased transfusion needs , in five patients with thalassemia intermedia treated with HU alone or in combination with SPB .
 adverse effect: increases in total Hb, HU; adverse effect: increases in total Hb, SPB
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  increases in total Hb, HU; increases in total Hb, SPB 
Answer:
 adverse effect: increases in total Hb, HU; adverse effect: increases in total Hb, SPB