7494
With itraconazole , hepatotoxic reactions have only very rarely been reported , and histologic data are lacking .
 adverse effect: hepatotoxic, itraconazole
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  hepatotoxic, itraconazole 
Answer:
 adverse effect: hepatotoxic, itraconazole