9349
The reversal of heparin by protamine may cause severe hemodynamic deterioration , characterized by systemic hypotension , pulmonary hypertension , and bronchoconstriction .
 adverse effect: bronchoconstriction, protamine; adverse effect: pulmonary hypertension, protamine; adverse effect: severe hemodynamic deterioration, protamine; adverse effect: systemic hypotension, protamine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  bronchoconstriction, protamine; pulmonary hypertension, protamine; severe hemodynamic deterioration, protamine; systemic hypotension, protamine 
Answer:
 adverse effect: bronchoconstriction, protamine; adverse effect: pulmonary hypertension, protamine; adverse effect: severe hemodynamic deterioration, protamine; adverse effect: systemic hypotension, protamine