4186
Because of serious side effects of an increase in the QT interval causing torsades de pointes , dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting .
 adverse effect: increase in the QT interval, dofetilide; adverse effect: torsades de pointes, dofetilide
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  increase in the QT interval, dofetilide; torsades de pointes, dofetilide 
Answer:
 adverse effect: increase in the QT interval, dofetilide; adverse effect: torsades de pointes, dofetilide