6963
Case 2 , a 29-year - old woman , developed bilateral optic neuritis combined with numbness of the lower extremities as well as bowel and bladder dysfunction after a 22-month use of recombinant interferon alpha-2b for chronic myelogenous leukemia .
 adverse effect: bilateral optic neuritis, recombinant interferon alpha-2b; adverse effect: bowel and bladder dysfunction, recombinant interferon alpha-2b; adverse effect: numbness of the lower extremities, recombinant interferon alpha-2b
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  bilateral optic neuritis, recombinant interferon alpha-2b; bowel and bladder dysfunction, recombinant interferon alpha-2b; numbness of the lower extremities, recombinant interferon alpha-2b 
Answer:
 adverse effect: bilateral optic neuritis, recombinant interferon alpha-2b; adverse effect: bowel and bladder dysfunction, recombinant interferon alpha-2b; adverse effect: numbness of the lower extremities, recombinant interferon alpha-2b