7073
We report a case of intrathecal methotrexate neurotoxicity manifesting as left arm weakness and aphasia .
 adverse effect: aphasia, methotrexate; adverse effect: left arm weakness, methotrexate; adverse effect: neurotoxicity, methotrexate
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  aphasia, methotrexate; left arm weakness, methotrexate; neurotoxicity, methotrexate 
Answer:
 adverse effect: aphasia, methotrexate; adverse effect: left arm weakness, methotrexate; adverse effect: neurotoxicity, methotrexate