6254
Worsening of neurologic syndrome in patients with Wilson 's disease with initial penicillamine therapy .
 adverse effect: Worsening of neurologic syndrome, penicillamine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  Worsening of neurologic syndrome, penicillamine 
Answer:
 adverse effect: Worsening of neurologic syndrome, penicillamine