2832
The principle treatment for DPD - deficient patients with severe acute 5-FU reactions is supportive care ; however , the administration of thymidine potentially may reverse severe 5-FU - induced neurologic symptoms such as encephalopathy and coma .
 adverse effect: coma, 5-FU; adverse effect: coma, 5-FU; adverse effect: encephalopathy, 5-FU; adverse effect: encephalopathy, 5-FU; adverse effect: neurologic symptoms, 5-FU; adverse effect: neurologic symptoms, 5-FU; adverse effect: severe acute 5-FU reactions, 5-FU; adverse effect: severe acute 5-FU reactions, 5-FU
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  coma, 5-FU; coma, 5-FU; encephalopathy, 5-FU; encephalopathy, 5-FU; neurologic symptoms, 5-FU; neurologic symptoms, 5-FU; severe acute 5-FU reactions, 5-FU; severe acute 5-FU reactions, 5-FU 
Answer:
 adverse effect: coma, 5-FU; adverse effect: coma, 5-FU; adverse effect: encephalopathy, 5-FU; adverse effect: encephalopathy, 5-FU; adverse effect: neurologic symptoms, 5-FU; adverse effect: neurologic symptoms, 5-FU; adverse effect: severe acute 5-FU reactions, 5-FU; adverse effect: severe acute 5-FU reactions, 5-FU