1111
We report the occurrence of renal failure due to cholesterol crystal embolization following thrombolytic therapy with intravenous recombinant tissue - type plasminogen activator ( t - PA ) .
 adverse effect: cholesterol crystal embolization, recombinant tissue - type plasminogen activator; adverse effect: cholesterol crystal embolization, t - PA; adverse effect: renal failure, recombinant tissue - type plasminogen activator; adverse effect: renal failure, t - PA
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  cholesterol crystal embolization, recombinant tissue - type plasminogen activator; cholesterol crystal embolization, t - PA; renal failure, recombinant tissue - type plasminogen activator; renal failure, t - PA 
Answer:
 adverse effect: cholesterol crystal embolization, recombinant tissue - type plasminogen activator; adverse effect: cholesterol crystal embolization, t - PA; adverse effect: renal failure, recombinant tissue - type plasminogen activator; adverse effect: renal failure, t - PA