4117
However , given the clinically significant result to the interaction between tolazoline and cimetidine we report , the use of cimetidine in tolazoline induced upper gastrointestinal hemorrhage should deserve more attention .
 adverse effect: upper gastrointestinal hemorrhage, cimetidine; adverse effect: upper gastrointestinal hemorrhage, cimetidine; adverse effect: upper gastrointestinal hemorrhage, tolazoline; adverse effect: upper gastrointestinal hemorrhage, tolazoline
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  upper gastrointestinal hemorrhage, cimetidine; upper gastrointestinal hemorrhage, cimetidine; upper gastrointestinal hemorrhage, tolazoline; upper gastrointestinal hemorrhage, tolazoline 
Answer:
 adverse effect: upper gastrointestinal hemorrhage, cimetidine; adverse effect: upper gastrointestinal hemorrhage, cimetidine; adverse effect: upper gastrointestinal hemorrhage, tolazoline; adverse effect: upper gastrointestinal hemorrhage, tolazoline