9900
Administration of lamotrigine , especially in combination with valproic acid , may lead to the development of TEN .
 adverse effect: TEN, lamotrigine; adverse effect: TEN, valproic acid
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  TEN, lamotrigine; TEN, valproic acid 
Answer:
 adverse effect: TEN, lamotrigine; adverse effect: TEN, valproic acid