1286
After rechallenge with monotherapy pegvisomant , however , the hepatic enzyme disturbances reappeared within a few weeks , indicating that most likely pegvisomant alone and not the long - acting somatostatin analog or the combination of these two drugs was responsible for this case of drug - induced hepatitis .
 adverse effect: hepatic enzyme disturbances, pegvisomant; adverse effect: hepatic enzyme disturbances, pegvisomant; adverse effect: hepatitis, pegvisomant
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  hepatic enzyme disturbances, pegvisomant; hepatic enzyme disturbances, pegvisomant; hepatitis, pegvisomant 
Answer:
 adverse effect: hepatic enzyme disturbances, pegvisomant; adverse effect: hepatic enzyme disturbances, pegvisomant; adverse effect: hepatitis, pegvisomant