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The cause of these previously unreported side effects of niacin therapy is uncertain but may be related to prostaglandin - mediated vasodilatation , hyperalgesia of sensory nerve receptors , and potentiation of inflammation in the gingiva with referral of pain to the teeth .
 adverse effect: hyperalgesia of sensory nerve receptors, niacin; adverse effect: pain to the teeth, niacin; adverse effect: potentiation of inflammation in the gingiva, niacin; adverse effect: prostaglandin - mediated vasodilatation, niacin
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  hyperalgesia of sensory nerve receptors, niacin; pain to the teeth, niacin; potentiation of inflammation in the gingiva, niacin; prostaglandin - mediated vasodilatation, niacin 
Answer:
 adverse effect: hyperalgesia of sensory nerve receptors, niacin; adverse effect: pain to the teeth, niacin; adverse effect: potentiation of inflammation in the gingiva, niacin; adverse effect: prostaglandin - mediated vasodilatation, niacin