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We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII .
 adverse effect: thrombotic left middle cerebral artery distribution stroke, pFVIII
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  thrombotic left middle cerebral artery distribution stroke, pFVIII 
Answer:
 adverse effect: thrombotic left middle cerebral artery distribution stroke, pFVIII