1538
PATIENTS : Two patients , ages 40 and 51 years , undergoing treatment with interferon alfa for malignant neoplasms experienced sudden bilateral , sequential visual loss with disc - related field defects and segmental optic disc edema .
 adverse effect: sudden bilateral , sequential visual loss, interferon alfa
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  sudden bilateral , sequential visual loss, interferon alfa 
Answer:
 adverse effect: sudden bilateral , sequential visual loss, interferon alfa