6553
Though proteinuria and nephrotic syndrome is a rare adverse effect of IFN - beta-1b therapy , physicians treating MS patients with this agent should pay careful attention to new clinical symptoms and laboratory findings .
 adverse effect: nephrotic syndrome, IFN - beta-1b; adverse effect: proteinuria, IFN - beta-1b
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  nephrotic syndrome, IFN - beta-1b; proteinuria, IFN - beta-1b 
Answer:
 adverse effect: nephrotic syndrome, IFN - beta-1b; adverse effect: proteinuria, IFN - beta-1b