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Recombinant human interferon - alpha has been used in the treatment of several cancers , but there have been several reports that it may exacerbate psoriasis or trigger off its onset .
 adverse effect: exacerbate psoriasis or trigger off its onset, Recombinant human interferon - alpha
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  exacerbate psoriasis or trigger off its onset, Recombinant human interferon - alpha 
Answer:
 adverse effect: exacerbate psoriasis or trigger off its onset, Recombinant human interferon - alpha