5122
Apparent central nervous system depression in infants after the use of topical brimonidine .
 adverse effect: central nervous system depression, brimonidine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  central nervous system depression, brimonidine 
Answer:
 adverse effect: central nervous system depression, brimonidine