1756
In the absence of mucositis or diarrhea , severe dermatologic toxicity following a single low dose of the drug suggests an ' allergic ' or acute hypersensitivity reaction to MTX in this patient .
 adverse effect: acute hypersensitivity reaction, MTX; adverse effect: severe dermatologic toxicity, MTX
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  acute hypersensitivity reaction, MTX; severe dermatologic toxicity, MTX 
Answer:
 adverse effect: acute hypersensitivity reaction, MTX; adverse effect: severe dermatologic toxicity, MTX