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In one instance a systemic hypoglycemic reaction resulting in head trauma and confusion ended in an emegency hospital admission following the substitution of acetohexamide for acetazolamide .
 adverse effect: confusion, acetohexamide; adverse effect: head trauma, acetohexamide; adverse effect: systemic hypoglycemic reaction, acetohexamide
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  confusion, acetohexamide; head trauma, acetohexamide; systemic hypoglycemic reaction, acetohexamide 
Answer:
 adverse effect: confusion, acetohexamide; adverse effect: head trauma, acetohexamide; adverse effect: systemic hypoglycemic reaction, acetohexamide