1116
The multiple comedones and ruptured epidermoid cysts are newly reported adverse effects of imiquimod therapy .
 adverse effect: multiple comedones, imiquimod; adverse effect: ruptured epidermoid cysts, imiquimod
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  multiple comedones, imiquimod; ruptured epidermoid cysts, imiquimod 
Answer:
 adverse effect: multiple comedones, imiquimod; adverse effect: ruptured epidermoid cysts, imiquimod