5246
An episode of leukoencephalopathy is reported in a 13-year - old girl who , after standard radiotherapy for a posterior fossa medulloblastoma , received 8 treatments with a protocol containing a 4-hour infusion of 500 mg / m2 methotrexate and 12 mg intrathecal methotrexate .
 adverse effect: leukoencephalopathy, methotrexate; adverse effect: leukoencephalopathy, methotrexate
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  leukoencephalopathy, methotrexate; leukoencephalopathy, methotrexate 
Answer:
 adverse effect: leukoencephalopathy, methotrexate; adverse effect: leukoencephalopathy, methotrexate