12604
Rapid resolution of topiramate - induced angle - closure glaucoma with methylprednisolone and mannitol .
 adverse effect: angle - closure glaucoma, mannitol; adverse effect: angle - closure glaucoma, methylprednisolone; adverse effect: angle - closure glaucoma, topiramate
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  angle - closure glaucoma, mannitol; angle - closure glaucoma, methylprednisolone; angle - closure glaucoma, topiramate 
Answer:
 adverse effect: angle - closure glaucoma, mannitol; adverse effect: angle - closure glaucoma, methylprednisolone; adverse effect: angle - closure glaucoma, topiramate