12288
We report the case of a patient with increased cerebral cortical excitability following intoxication with flupirtine , a centrally acting analgesic and antispastic drug .
 adverse effect: increased cerebral cortical excitability, flupirtine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  increased cerebral cortical excitability, flupirtine 
Answer:
 adverse effect: increased cerebral cortical excitability, flupirtine