8720
The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate .
 adverse effect: encephalopathy, methotrexate
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  encephalopathy, methotrexate 
Answer:
 adverse effect: encephalopathy, methotrexate