3294
The patient 's clinical presentation , histologic features on liver biopsy and favorable course after stopping the drug suggest that barbiturates can be added to the list of agents which can cause submassive hepatic necrosis .
 adverse effect: submassive hepatic necrosis, barbiturates
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  submassive hepatic necrosis, barbiturates 
Answer:
 adverse effect: submassive hepatic necrosis, barbiturates