8520
The most commonly recognized toxic effect of ethambutol is optic neuropathy , which generally is considered uncommon and reversible in medical literature .
 adverse effect: optic neuropathy, ethambutol
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  optic neuropathy, ethambutol 
Answer:
 adverse effect: optic neuropathy, ethambutol