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We present two children with acute lymphocytic leukemia who developed leukoencephalopathy following administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy .
 adverse effect: leukoencephalopathy, ara = C; adverse effect: leukoencephalopathy, methotrexate
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  leukoencephalopathy, ara = C; leukoencephalopathy, methotrexate 
Answer:
 adverse effect: leukoencephalopathy, ara = C; adverse effect: leukoencephalopathy, methotrexate