4008
After only the third dose of pentamidine , it was noted that the patient 's heart rate had decreased to 48 beats / minute .
 adverse effect: heart rate had decreased, pentamidine
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  heart rate had decreased, pentamidine 
Answer:
 adverse effect: heart rate had decreased, pentamidine