1061
Rofecoxib , used for dysmenorrhea , caused a herpetiform fixed drug eruption predominantly involving the lips with classic clinical and histological findings in a red - brown lesion on the dorsal hand .
 adverse effect: herpetiform fixed drug eruption, Rofecoxib; adverse effect: red - brown lesion, Rofecoxib
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  herpetiform fixed drug eruption, Rofecoxib; red - brown lesion, Rofecoxib 
Answer:
 adverse effect: herpetiform fixed drug eruption, Rofecoxib; adverse effect: red - brown lesion, Rofecoxib