8539
Shortly after chemotherapy and an injection of pegfilgrastim , the patient developed poorly defined , rapidly progressive erythema , edema , and pain in his right forearm .
 adverse effect: edema, pegfilgrastim; adverse effect: pain in his right forearm, pegfilgrastim; adverse effect: rapidly progressive erythema, pegfilgrastim
Given options, please tell me the relationships of all the listed entity pairs.Output format is "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
 Entity Pairs:  edema, pegfilgrastim; pain in his right forearm, pegfilgrastim; rapidly progressive erythema, pegfilgrastim 
Answer:
 adverse effect: edema, pegfilgrastim; adverse effect: pain in his right forearm, pegfilgrastim; adverse effect: rapidly progressive erythema, pegfilgrastim