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However , prolongation of 5-FU half - life and an increase in INR have been reported with the concurrent use of 5-FU and warfarin .
 increase in INR, 5-FU; increase in INR, warfarin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 increase in INR, 5-FU; increase in INR, warfarin