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We report three patients , all of whom had preexisting diabetic dyslipidemia , who showed a profound reduction in plasma HDL cholesterol and apolipoprotein AI levels soon after the initiation of rosiglitazone therapy .
 reduction in plasma HDL cholesterol and apolipoprotein AI levels, rosiglitazone
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 reduction in plasma HDL cholesterol and apolipoprotein AI levels, rosiglitazone