8001
A 66-year - old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D - penicillamine ( D - Pen ) treatment , although the leukopenia was not markedly severe .
 anemia, D - Pen; anemia, D - penicillamine; thrombocytopenia, D - Pen; thrombocytopenia, D - penicillamine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 anemia, D - Pen; anemia, D - penicillamine; thrombocytopenia, D - Pen; thrombocytopenia, D - penicillamine