2113
In case 1 , a total daily dose of 25 mg sertraline , with nondetectable sertraline and desmethylsertraline blood levels , resulted in a doubling of the lamotrigine blood level with symptoms of toxicity .
 doubling of the lamotrigine blood level, desmethylsertraline; doubling of the lamotrigine blood level, lamotrigine; doubling of the lamotrigine blood level, sertraline; doubling of the lamotrigine blood level, sertraline; symptoms of toxicity, desmethylsertraline; symptoms of toxicity, lamotrigine; symptoms of toxicity, sertraline; symptoms of toxicity, sertraline
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 doubling of the lamotrigine blood level, desmethylsertraline; doubling of the lamotrigine blood level, lamotrigine; doubling of the lamotrigine blood level, sertraline; doubling of the lamotrigine blood level, sertraline; symptoms of toxicity, desmethylsertraline; symptoms of toxicity, lamotrigine; symptoms of toxicity, sertraline; symptoms of toxicity, sertraline