1641
Angioedema , a rare side effect of carbamazepine , involves vascular leakage in dermis and subcutis mediated by immunoglobulin E and/or bradykinins .
 Angioedema, carbamazepine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 Angioedema, carbamazepine