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Use of the Naranjo adverse drug reaction probability scale indicated a probable relationship ( score of 5 ) between the patient 's development of hepatotoxicity and the TMP - SMX therapy .
 hepatotoxicity, TMP - SMX
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 hepatotoxicity, TMP - SMX