12350
Further studies are necessary to evaluate whether the study of HLA antigens may be a very useful tool to detect the patients with a predisposition to develop autoimmune thyroiditis , in order to make a early diagnosis of thyroid disorders during the IFN - alpha treatment .
 autoimmune thyroiditis, IFN - alpha; thyroid disorders, IFN - alpha
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 autoimmune thyroiditis, IFN - alpha; thyroid disorders, IFN - alpha