6248
This report describes a 13-year - old female with a right frontal high - grade glioma and complex partial seizures who developed localized purpura after 23 months of lamotrigine monotherapy .
 localized purpura, lamotrigine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 localized purpura, lamotrigine