1097
The first reported case , in an adult , of cholestyramine induced hyperchloremic metabolic acidosis is a 70 year old female with a two year history of primary biliary cirrhosis confirmed by histologic and immunologic criteria .
 hyperchloremic metabolic acidosis, cholestyramine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 hyperchloremic metabolic acidosis, cholestyramine