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Well - known signs of methotrexate toxicity include bone marrow suppression and oral and gastrointestinal ulceration .
 bone marrow suppression, methotrexate; methotrexate toxicity, methotrexate; oral and gastrointestinal ulceration, methotrexate
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 bone marrow suppression, methotrexate; methotrexate toxicity, methotrexate; oral and gastrointestinal ulceration, methotrexate