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a common side effect of strict elimination after extended periods of use is headaches from caffeine withdrawal , which is also a clear sign of the addiction .
 headaches, caffeine withdrawal
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: component whole, NA, instrument agency, member collection, cause effect, entity destination, content container, message topic, product producer, entity origin 
Text: {0} 
Answer:
 headaches, caffeine withdrawal