6675
This severe illness was likely caused by minocycline , and we speculate that minocycline may have acted as a superantigen , causing lymphocyte over - activation and massive cytokine release .
 lymphocyte over - activation, minocycline; massive cytokine release, minocycline; severe illness, minocycline
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 lymphocyte over - activation, minocycline; massive cytokine release, minocycline; severe illness, minocycline