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A 22-year - old black man developed fever , chills , fatigue , night sweats , tender lymphadenopathy , and a generalized , pruritic , macular eruption 3 weeks after starting minocycline therapy for acne .
 chills, minocycline; fatigue, minocycline; fever, minocycline; generalized , pruritic , macular eruption, minocycline; night sweats, minocycline
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 chills, minocycline; fatigue, minocycline; fever, minocycline; generalized , pruritic , macular eruption, minocycline; night sweats, minocycline