455
Hypersensitivity to carboplatin has been reported in up to 44 % of patients receiving this antineoplastic agent , usually occurring after several courses of treatment .
 Hypersensitivity, carboplatin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 Hypersensitivity, carboplatin