7874
Argatroban is hepatically cleared and may be the preferred direct thrombin inhibitor in the presence of significant renal impairment , but conversely has prolonged effects in hepatic failure .
 hepatic failure, Argatroban
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 hepatic failure, Argatroban