2550
We report a myeloma patient who developed severe paralytic ileus during bortezomib therapy , which presented in the context of progressive constipation without other known causes and which regressed promptly with medical management after drug cessation , suggesting a direct causal relationship .
 severe paralytic ileus, bortezomib
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 severe paralytic ileus, bortezomib