2262
However , there remain questions concerning whether these drugs , especially methimazole ( MMI ) , may be associated with aplasia cutis congenita ( ACC ) and how best to avoid impairment of fetal thyroid function during their use .
 ACC, methimazole; ACC, MMI; aplasia cutis congenita, methimazole; aplasia cutis congenita, MMI
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 ACC, methimazole; ACC, MMI; aplasia cutis congenita, methimazole; aplasia cutis congenita, MMI