6029
Exacerbation of 5-FU dermatologic toxicities in patients with preexisting conditions suggests the importance of aggressive ocular prophylaxis , using frequent ocular lubrication and topical steroid preparations with concurrent medical management of pre - existing dermatologic conditions .
 dermatologic toxicities, 5-FU
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 dermatologic toxicities, 5-FU