1445
Two cases of lepromatous leprosy with erythema nodosum leprosum who were on high doses of clofazimine , showed discoloration of nail plate , subungual hyperkeratosis and onycholysis .
 discoloration of nail plate, clofazimine; onycholysis, clofazimine; subungual hyperkeratosis, clofazimine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 discoloration of nail plate, clofazimine; onycholysis, clofazimine; subungual hyperkeratosis, clofazimine