10072
Worsening of neurologic syndrome in patients with Wilson 's disease with initial penicillamine therapy .
 Worsening of neurologic syndrome, penicillamine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 Worsening of neurologic syndrome, penicillamine