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A 77-year - old man developed ankle , hand , and facial swelling 2 weeks after starting rosiglitazone .
 ankle , hand , and facial swelling, rosiglitazone
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 ankle , hand , and facial swelling, rosiglitazone