5221
A small initial dose of prazosin ranging from 0.5 to 1 mg has been recommended to avoid the first - dose phenomenon characterized by a sudden and severe drop in blood pressure after the administration of the first dose of prazosin .
 severe drop in blood pressure, prazosin; severe drop in blood pressure, prazosin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 severe drop in blood pressure, prazosin; severe drop in blood pressure, prazosin