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Four months after receiving an orthotopic liver transplant , a 51-year - old man was admitted for progressive liver failure and severe hepatocellular necrosis thought to be due to tacrolimus .
 progressive liver failure, tacrolimus; severe hepatocellular necrosis, tacrolimus
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 progressive liver failure, tacrolimus; severe hepatocellular necrosis, tacrolimus