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Coadministration of antidepressant agents such as nefazodone , or any other drug that inhibits the CYP3A4 isoenzyme subfamily , should be anticipated to interfere with tacrolimus metabolism .
 interfere with tacrolimus metabolism, nefazodone; interfere with tacrolimus metabolism, tacrolimus
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 interfere with tacrolimus metabolism, nefazodone; interfere with tacrolimus metabolism, tacrolimus