12126
To our knowledge , this is the first granulomatous reaction described after calcium hydroxylapatite injection .
 granulomatous reaction, calcium hydroxylapatite
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 granulomatous reaction, calcium hydroxylapatite