13320
Soon after introduction of insulin therapy , she developed severe anasarca , including marked peripheral oedema , ascites and pleural effusion .
 ascites, insulin; peripheral oedema, insulin; pleural effusion, insulin; severe anasarca, insulin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 ascites, insulin; peripheral oedema, insulin; pleural effusion, insulin; severe anasarca, insulin