10760
The pathophysiological mechanisms remain unknown , although the drug could act through massive cytokines liberation after destruction of CD20 positive cells by rituximab .
 destruction of CD20 positive cells, rituximab; massive cytokines liberation, rituximab
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 destruction of CD20 positive cells, rituximab; massive cytokines liberation, rituximab