3811
Thus , we confirm that desensitization may be a safe procedure in patients with cancer who experience methotrexate - induced anaphylaxis .
 anaphylaxis, methotrexate
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 anaphylaxis, methotrexate