9091
Only after three subsequent episodes of severe , symptomatic thrombocytopenia over the next four weeks did he say , upon repeat questioning , that he had continued to take quinine for night leg cramps .
 thrombocytopenia, quinine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 thrombocytopenia, quinine