8192
We report the case of a patient with increased cerebral cortical excitability following intoxication with flupirtine , a centrally acting analgesic and antispastic drug .
 increased cerebral cortical excitability, flupirtine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 increased cerebral cortical excitability, flupirtine