4380
A 17-year - old boy with acute lymphoblastic leukemia developed acute renal failure within 48 h of an intravenous high - dose methotrexate ( 5 g / m2 ) infusion .
 acute renal failure, methotrexate
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 acute renal failure, methotrexate