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In one patient the vasculitis resolved after termination of the ciprofloxacin therapy ; in the other patient the ciprofloxacin - induced hemorrhagic vasculitis was superimposed on a severe forefoot infection , leading to progressive gangrene and a below - knee amputation .
 below - knee amputation, ciprofloxacin; hemorrhagic vasculitis, ciprofloxacin; progressive gangrene, ciprofloxacin; severe forefoot infection, ciprofloxacin; vasculitis, ciprofloxacin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 below - knee amputation, ciprofloxacin; hemorrhagic vasculitis, ciprofloxacin; progressive gangrene, ciprofloxacin; severe forefoot infection, ciprofloxacin; vasculitis, ciprofloxacin