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We report a case of intrathecal methotrexate neurotoxicity manifesting as left arm weakness and aphasia .
 aphasia, methotrexate; left arm weakness, methotrexate; neurotoxicity, methotrexate
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 aphasia, methotrexate; left arm weakness, methotrexate; neurotoxicity, methotrexate