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We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII .
 thrombotic left middle cerebral artery distribution stroke, pFVIII
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 thrombotic left middle cerebral artery distribution stroke, pFVIII