4255
Intravenous cytarabine and methotrexate appear to act synergistically to enhance the potential for central nervous system toxicity .
 central nervous system toxicity, cytarabine; central nervous system toxicity, methotrexate
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 central nervous system toxicity, cytarabine; central nervous system toxicity, methotrexate