5244
CONCLUSIONS : In our reported case , a local hyperproduction of TNF - alpha from macrophages that was induced by the injected insulin could explain the dedifferentiation of the adipocytes of the subcutaneous tissue and the reversion that was induced by the local injection of dexamethasone .
 dedifferentiation of the adipocytes, insulin; hyperproduction of TNF - alpha, insulin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 dedifferentiation of the adipocytes, insulin; hyperproduction of TNF - alpha, insulin