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BACKGROUND : Colchicine has a known adverse effect on wound healing through its inhibitory effect on tubulin - dependent cell functions and through collagenase activation .
 adverse effect on wound healing, Colchicine; collagenase activation, Colchicine
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect on wound healing, Colchicine; collagenase activation, Colchicine