11281
The cause of these previously unreported side effects of niacin therapy is uncertain but may be related to prostaglandin - mediated vasodilatation , hyperalgesia of sensory nerve receptors , and potentiation of inflammation in the gingiva with referral of pain to the teeth .
 hyperalgesia of sensory nerve receptors, niacin; pain to the teeth, niacin; potentiation of inflammation in the gingiva, niacin; prostaglandin - mediated vasodilatation, niacin
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 hyperalgesia of sensory nerve receptors, niacin; pain to the teeth, niacin; potentiation of inflammation in the gingiva, niacin; prostaglandin - mediated vasodilatation, niacin