10238
Motor fluctuations appear after 2 - 3 years of levodopa treatment , and affect at least 50 % of patients after five years .
 Motor fluctuations, levodopa
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 Motor fluctuations, levodopa