8103
On the fifth day after administration of a high dose of ARA - C ( 2 g / m2 intravenously every 12 hours ) , she developed bullous lesions on the hands and soles that disseminated , evolving to necrosis , sepsis , and death on the 22nd day .
 bullous lesions on the hands and soles that disseminated , evolving to necrosis, ARA - C; death, ARA - C; sepsis, ARA - C
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 bullous lesions on the hands and soles that disseminated , evolving to necrosis, ARA - C; death, ARA - C; sepsis, ARA - C