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We conclude that quinine does not improve the survival of adult patients with de novo AML, even though it improves CR rate in a small subgroup of patients defined by rhodamine 123 efflux.
 a small subgroup of patients defined by rhodamine 123 efflux: Subject; rhodamine 123 efflux: Subject.Disorder; a small subgroup: Subject.Population; improves CR rate: Effect; quinine: Treatment; de novo AML: Treatment.Disorder; quinine: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: potential therapeutic event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Treatment.Time_elapsed, Subject.Disorder, Subject.Race, Treatment.Route, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 a small subgroup of patients defined by rhodamine 123 efflux: Subject; rhodamine 123 efflux: Subject.Disorder; a small subgroup: Subject.Population; improves CR rate: Effect; quinine: Treatment; de novo AML: Treatment.Disorder; quinine: Treatment.Drug