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Simvastatin plasma concentration increased 30 times in this patient and statin induced muscle toxicity is related to the concentration of the statin in blood.
 Simvastatin plasma concentration increased 30 times in this patient: Subject; Simvastatin plasma concentration increased 30 times: Subject.Disorder; muscle toxicity: Effect; statin: Treatment; statin: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 Simvastatin plasma concentration increased 30 times in this patient: Subject; Simvastatin plasma concentration increased 30 times: Subject.Disorder; muscle toxicity: Effect; statin: Treatment; statin: Treatment.Drug