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In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 200 mg intravenous dose of lorcainide.
 eight patients: Subject; eight: Subject.Population; mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L: Effect; a single 200 mg intravenous dose of lorcainide: Treatment; a single 200 mg: Treatment.Dosage; intravenous: Treatment.Route; lorcainide: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 eight patients: Subject; eight: Subject.Population; mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L: Effect; a single 200 mg intravenous dose of lorcainide: Treatment; a single 200 mg: Treatment.Dosage; intravenous: Treatment.Route; lorcainide: Treatment.Drug