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Hypothyroidism, occurring in up to 11 percent of patients treated with amiodarone, can also alter drug metabolism and sensitize the central nervous system, thus increasing the potential for toxicity.
 11 percent of patients: Subject; 11 percent: Subject.Population; Hypothyroidism: Effect; amiodarone: Treatment; amiodarone: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 11 percent of patients: Subject; 11 percent: Subject.Population; Hypothyroidism: Effect; amiodarone: Treatment; amiodarone: Treatment.Drug