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Intrathecal chemotherapy with methotrexate or cytosine arabinoside is the standard approach to prophylaxis and treatment of central nervous system leukemia in children.
 children: Subject; children: Subject.Age; Intrathecal chemotherapy with methotrexate or cytosine arabinoside: Treatment; central nervous system leukemia: Treatment.Disorder; methotrexate: Treatment.Drug; cytosine arabinoside: Treatment.Drug; Intrathecal chemotherapy: Treatment.Route
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: potential therapeutic event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Treatment.Time_elapsed, Subject.Disorder, Subject.Race, Treatment.Route, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 children: Subject; children: Subject.Age; Intrathecal chemotherapy with methotrexate or cytosine arabinoside: Treatment; central nervous system leukemia: Treatment.Disorder; methotrexate: Treatment.Drug; cytosine arabinoside: Treatment.Drug; Intrathecal chemotherapy: Treatment.Route