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CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.
 an 11-year old male with Budd-Chiari syndrome: Subject; 11-year old: Subject.Age; male: Subject.Gender; Budd-Chiari syndrome: Subject.Disorder; profound worsening of chronic aphthous ulcers: Effect; immunosuppressive therapy was changed from tacrolimus to sirolimus: Treatment; tacrolimus: Treatment.Drug; sirolimus: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 an 11-year old male with Budd-Chiari syndrome: Subject; 11-year old: Subject.Age; male: Subject.Gender; Budd-Chiari syndrome: Subject.Disorder; profound worsening of chronic aphthous ulcers: Effect; immunosuppressive therapy was changed from tacrolimus to sirolimus: Treatment; tacrolimus: Treatment.Drug; sirolimus: Treatment.Drug