543
Although his renal function recovered completely with high-dose leucovorin, hemodialysis, charcoal hemoperfusion, and carboxypeptidase G2, we present this case to emphasize that signs of renal toxicity may be present as early as 2 hours after the completion of a 4-hour MTX infusion, and to suggest that monitoring for MTX toxicity should perhaps begin within a few hours after the completion of 4-hour MTX infusion.
 renal toxicity: Effect; 2 hours after the completion of a 4-hour MTX infusion: Treatment; 4-hour: Treatment.Duration; MTX: Treatment.Drug; infusion: Treatment.Route; 2 hours: Treatment.Time_elapsed
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 renal toxicity: Effect; 2 hours after the completion of a 4-hour MTX infusion: Treatment; 4-hour: Treatment.Duration; MTX: Treatment.Drug; infusion: Treatment.Route; 2 hours: Treatment.Time_elapsed