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During dose-finding studies for intravenous proton pump inhibitors omeprazole and pantoprazole, three of six young female volunteers receiving omeprazole and two young female volunteers receiving pantoprazole developed peripheral edema within 8 hr when high doses of the proton pump inhibitors were applied by continuous infusion together with large volumes of fluid.
 three of six young female volunteers: Subject; three: Subject.Population; young: Subject.Age; female: Subject.Gender; peripheral edema within 8 hr: Effect; omeprazole: Treatment; high doses of the proton pump inhibitors were applied by continuous infusion together with large volumes of fluid: Treatment; omeprazole: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 three of six young female volunteers: Subject; three: Subject.Population; young: Subject.Age; female: Subject.Gender; peripheral edema within 8 hr: Effect; omeprazole: Treatment; high doses of the proton pump inhibitors were applied by continuous infusion together with large volumes of fluid: Treatment; omeprazole: Treatment.Drug