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Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia.
 Six of 13 outpatients with schizophrenia: Subject; Six of 13: Subject.Population; intolerable affect, including feelings of agitation and depression and periods of crying and insomnia: Effect; a ten-week open trial of risperidone: Treatment; risperidone: Treatment.Drug; a ten-week: Treatment.Duration; schizophrenia: Treatment.Disorder
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 Six of 13 outpatients with schizophrenia: Subject; Six of 13: Subject.Population; intolerable affect, including feelings of agitation and depression and periods of crying and insomnia: Effect; a ten-week open trial of risperidone: Treatment; risperidone: Treatment.Drug; a ten-week: Treatment.Duration; schizophrenia: Treatment.Disorder