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The primary efficacy population consisted of 1754 patients (> or =18 years) with severe sepsis and a high INR (> or =1.2) randomly assigned to intravenous infusion of either tifacogin (0.025 mg/kg per hour for 96 hours, n = 880) or placebo (arginine citrate buffer, n = 874), and 201 patients with a low INR (<1.2) randomly assigned to receive the same dose of either tifacogin or placebo.
 1754 patients (> or =18 years) with severe sepsis and a high INR: Subject; 1754: Subject.Age; tifacogin: Treatment; tifacogin: Treatment.Drug; severe sepsis: Treatment.Disorder
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: potential therapeutic event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Treatment.Time_elapsed, Subject.Disorder, Subject.Race, Treatment.Route, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 1754 patients (> or =18 years) with severe sepsis and a high INR: Subject; 1754: Subject.Age; tifacogin: Treatment; tifacogin: Treatment.Drug; severe sepsis: Treatment.Disorder