795
Although the two local anesthetics usually do not cause methemoglobinemia, we suspect that the displacement of lidocaine from protein binding by bupivacaine, in combination with metabolic acidosis and treatment with other oxidants, was the reason for the development of methemoglobinemia.
 methemoglobinemia: Effect; the displacement of lidocaine from protein binding by bupivacaine, in combination with metabolic acidosis and treatment with other oxidants: Treatment; bupivacaine: Treatment.Drug; lidocaine: Treatment.Drug; metabolic acidosis: Treatment.Drug; oxidants: Treatment.Drug; metabolic acidosis: Combination.Drug; oxidants: Combination.Drug; bupivacaine: Combination.Drug; lidocaine: Combination.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 methemoglobinemia: Effect; the displacement of lidocaine from protein binding by bupivacaine, in combination with metabolic acidosis and treatment with other oxidants: Treatment; bupivacaine: Treatment.Drug; lidocaine: Treatment.Drug; metabolic acidosis: Treatment.Drug; oxidants: Treatment.Drug; metabolic acidosis: Combination.Drug; oxidants: Combination.Drug; bupivacaine: Combination.Drug; lidocaine: Combination.Drug