5470
In this study, we investigated the ability of the major envelope glycoprotein of HIV , glycoprotein 120 ( gp120 ), to regulate intercellular adhesion molecule-1 ( ICAM-1 ) expression in glial cells , because ICAM-1 is important in mediating immune responsiveness in the CNS , facilitating entry of HIV -infected cells into the CNS , and promoting syncytia formation.
 ( cell type: glial cells, None) , ( cell type: HIV -infected cells, None) , ( protein: ICAM-1, None) , ( protein: major envelope glycoprotein, None) , ( protein: intercellular adhesion molecule-1, None) , ( protein: glycoprotein 120, None) , ( protein: gp120, None) , ( protein: ICAM-1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: glial cells, None) , ( cell type: HIV -infected cells, None) , ( protein: ICAM-1, None) , ( protein: major envelope glycoprotein, None) , ( protein: intercellular adhesion molecule-1, None) , ( protein: glycoprotein 120, None) , ( protein: gp120, None) , ( protein: ICAM-1, None) 