289
We have recently demonstrated that stimulation of human T and natural killer cells with IL-12 induces tyrosine phosphorylation of the Janus family tyrosine kinase JAK2 and Tyk2 , implicating these kinases in the immediate biochemical response to IL-12 .
 ( protein: JAK2, None) , ( protein: IL-12, None) , ( protein: IL-12, None) , ( protein: Tyk2, None) , ( protein: kinases, None) , ( protein: Janus family tyrosine kinase, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: JAK2, None) , ( protein: IL-12, None) , ( protein: IL-12, None) , ( protein: Tyk2, None) , ( protein: kinases, None) , ( protein: Janus family tyrosine kinase, None) 