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As HSF1 can function as both an activator of heat shock genes and a repressor of non-heat shock genes such as IL1B and c- fos, we have examined the potential role of HSF1 in the effects of NSAIDs on gene expression in a human monocytic cell line THP-1 .
 ( protein: HSF1, None) , ( protein: HSF1, None) , ( DNA: heat shock genes, None) , ( cell line: monocytic cell line THP-1, None) , ( DNA: non-heat shock genes, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: HSF1, None) , ( protein: HSF1, None) , ( DNA: heat shock genes, None) , ( cell line: monocytic cell line THP-1, None) , ( DNA: non-heat shock genes, None) 