14854
Remarkably, we observed that these samples displayed a persistent expression of the c-fos protooncogene , associated to an increased AP-1 DNA-binding activity, whereas no variations of CREB or NF-kB were detected.
 ( protein: AP-1, None) , ( protein: NF-kB, None) , ( protein: CREB, None) , ( DNA: c-fos protooncogene, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: AP-1, None) , ( protein: NF-kB, None) , ( protein: CREB, None) , ( DNA: c-fos protooncogene, None) 