10843
Patients with one type of major histocompatibility complex class II combined immunodeficiency have mutations in a gene termed class II transactivator ( CIITA ), which coordinately controls the transcription of the three major human class II genes , HLA -DR , -DQ , and -DP .
 ( protein: class II transactivator, None) , ( protein: major histocompatibility complex class II, None) , ( DNA: human class II genes, None) , ( protein: CIITA, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: class II transactivator, None) , ( protein: major histocompatibility complex class II, None) , ( DNA: human class II genes, None) , ( protein: CIITA, None) 