2678
Both sIgM- and sIgD- crosslinking with antibodies induced elevation of cAMP levels , phosphatidylinositol turnover , PKC activation and expression of Egr-1 and c-fos mRNA , although sIgM -crosslinking was more effective than sIgD -crosslinking , presumably due to the higher expression of sIgM than of sIgD .
 ( protein: sIgM, None) , ( protein: PKC, None) , ( protein: sIgM, None) , ( protein: sIgD, None) , ( protein: sIgD, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: sIgM, None) , ( protein: PKC, None) , ( protein: sIgM, None) , ( protein: sIgD, None) , ( protein: sIgD, None) 