6871
PI3-kinase activity was an upstream activator of PKB/Akt because the PI3-kinase inhibitor LY294002 blocked both constitutive PKB/Akt and factor-dependent PKB/Akt activity .
 ( protein: PKB/Akt, None) , ( protein: PI3-kinase, None) , ( protein: PKB/Akt, None) , ( protein: PI3-kinase, None) , ( protein: PKB/Akt, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: PKB/Akt, None) , ( protein: PI3-kinase, None) , ( protein: PKB/Akt, None) , ( protein: PI3-kinase, None) , ( protein: PKB/Akt, None) 