11550
Therefore, initiation of the EBV lytic cycle by the ZEBRA protein requires a function in addition to transcriptional activation ; a change of serine 186 to alanine in the DNA-binding domain of ZEBRA abolished this additional function and uncovered a new role for the ZEBRA protein in disruption of EBV latency.
 ( protein: ZEBRA, None) , ( protein: ZEBRA, None) , ( protein: DNA-binding domain, None) , ( protein: ZEBRA protein, None) , ( protein: ZEBRA protein, None) , ( protein: ZEBRA, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: ZEBRA, None) , ( protein: ZEBRA, None) , ( protein: DNA-binding domain, None) , ( protein: ZEBRA protein, None) , ( protein: ZEBRA protein, None) , ( protein: ZEBRA, None) 