8649
The substitution of Ile for Val augmented STAT6 activation , proliferation, and transcription activity of the Iepsilon promoter by IL-4 , whereas that of Arg for Gln did not change these IL-4 signals .
 ( protein: IL-4, None) , ( protein: STAT6, None) , ( DNA: Iepsilon promoter, None) , ( protein: IL-4, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-4, None) , ( protein: STAT6, None) , ( DNA: Iepsilon promoter, None) , ( protein: IL-4, None) 