10956
Secreted TNF-alpha mediated the enhancement of nuclear factor kappa B ( NF-kappa B ) and activator protein-1 ( AP-1 ) binding activity; in fact, the triggering of HLA-DR antigens in the presence of antihuman TNF-alpha -neutralizing antibodies did not upregulate NF-kappa B and AP-1 .
 ( protein: HLA-DR antigens, None) , ( protein: TNF-alpha, None) , ( protein: nuclear factor kappa B, None) , ( protein: antihuman TNF-alpha -neutralizing antibodies, None) , ( protein: TNF-alpha, None) , ( protein: AP-1, None) , ( protein: AP-1, None) , ( protein: NF-kappa B, None) , ( protein: NF-kappa B, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: HLA-DR antigens, None) , ( protein: TNF-alpha, None) , ( protein: nuclear factor kappa B, None) , ( protein: antihuman TNF-alpha -neutralizing antibodies, None) , ( protein: TNF-alpha, None) , ( protein: AP-1, None) , ( protein: AP-1, None) , ( protein: NF-kappa B, None) , ( protein: NF-kappa B, None) 