4107
In this work, we report that these anergic T cells are defective in their ability to up-regulate protein binding and transactivation at two critical IL-2 DNA enhancer elements : NF-AT ( nuclear factor of activated T cells ; a sequence that binds a heterotrimeric NFATp , Fos , and Jun protein complex ) and Activator Protein-1 ( AP-1 ) (that binds Fos and Jun heterodimers ).
 ( protein: Jun protein complex, None) , ( protein: Fos, None) , ( DNA: IL-2 DNA enhancer elements, None) , ( protein: nuclear factor of activated T cells, None) , ( protein: Activator Protein-1, None) , ( cell line: anergic T cells, None) , ( protein: AP-1, None) , ( protein: Fos and Jun heterodimers, None) , ( protein: NFATp, None) , ( protein: IL-2, None) , ( protein: NF-AT, None) , ( protein: heterotrimeric NFATp, None) , ( protein: heterotrimeric NFATp , Fos , and Jun protein complex, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: Jun protein complex, None) , ( protein: Fos, None) , ( DNA: IL-2 DNA enhancer elements, None) , ( protein: nuclear factor of activated T cells, None) , ( protein: Activator Protein-1, None) , ( cell line: anergic T cells, None) , ( protein: AP-1, None) , ( protein: Fos and Jun heterodimers, None) , ( protein: NFATp, None) , ( protein: IL-2, None) , ( protein: NF-AT, None) , ( protein: heterotrimeric NFATp, None) , ( protein: heterotrimeric NFATp , Fos , and Jun protein complex, None) 