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Recently, we demonstrated that the DSE are also cAMP-responsive elements ( CRE ), since they mediated activation signals elicited by cholera toxin ( Ctx ), a potent activator of the cAMP-dependent protein kinase A ( PKA ) signal transduction pathway .
 ( DNA: DSE, None) , ( protein: cholera toxin, None) , ( protein: Ctx, None) , ( protein: PKA, None) , ( protein: protein kinase A, None) , ( DNA: CRE, None) , ( DNA: cAMP-responsive elements, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: DSE, None) , ( protein: cholera toxin, None) , ( protein: Ctx, None) , ( protein: PKA, None) , ( protein: protein kinase A, None) , ( DNA: CRE, None) , ( DNA: cAMP-responsive elements, None) 