11495
However, little is known about negative regulation of IL-1beta expression at the transcriptional level , which may play an important role in anti-inflammatory and immunosuppressive effects .
 ( protein: IL-1beta, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-1beta, None) 