6452
Taken together, these findings suggest that AG-490 inhibits the JAK3 -mediated Type II signaling pathway but not the T cell receptor-derived Type I pathway and possesses therapeutic potential for T cell -derived pathologies such as graft-versus-host disease , allergy , and autoimmune disorders .
 ( cell type: T cell, None) , ( protein: JAK3, None) , ( cell type: T cell, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: T cell, None) , ( protein: JAK3, None) , ( cell type: T cell, None) 