5005
Although GM-CSF receptor is devoid of tyrosine kinase enzymatic activity , GM-CSF -induced peripheral blood polymorphonuclear leukocytes ( PMN ) functional activation is mediated by the phosphorylation of a large number of intracellular signaling molecules .
 ( protein: tyrosine kinase, None) , ( cell type: polymorphonuclear leukocytes, None) , ( protein: GM-CSF, None) , ( cell type: PMN, None) , ( cell line: GM-CSF -induced peripheral blood polymorphonuclear leukocytes, None) , ( protein: intracellular signaling molecules, None) , ( protein: GM-CSF, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: tyrosine kinase, None) , ( cell type: polymorphonuclear leukocytes, None) , ( protein: GM-CSF, None) , ( cell type: PMN, None) , ( cell line: GM-CSF -induced peripheral blood polymorphonuclear leukocytes, None) , ( protein: intracellular signaling molecules, None) , ( protein: GM-CSF, None) 