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A 49-year-old man with Crohn's disease treated with prednisone and mesalamine (5-ASA) developed worsening respiratory distress and fever.
 ( adverse event: developed ,  49-year-old man with Crohn's disease: Subject, 49-year-old: Subject.Age, man: Subject.Gender, worsening respiratory distress and fever.: Effect, prednisone and mesalamine (5-ASA): Treatment, Crohn's disease: Treatment.Disorder, mesalamine: Treatment.Drug, prednisone: Treatment.Drug, prednisone: Combination.Drug, mesalamine: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  49-year-old man with Crohn's disease: Subject, 49-year-old: Subject.Age, man: Subject.Gender, worsening respiratory distress and fever.: Effect, prednisone and mesalamine (5-ASA): Treatment, Crohn's disease: Treatment.Disorder, mesalamine: Treatment.Drug, prednisone: Treatment.Drug, prednisone: Combination.Drug, mesalamine: Combination.Drug) 