8549
Site-directed mutagenesis of the critical guanine nucleotides in the kappaB- Sp1 element documented the essential role of this site in activation-dependent fas promoter induction .
 ( DNA: kappaB- Sp1 element, None) , ( protein: Sp1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: kappaB- Sp1 element, None) , ( protein: Sp1, None) 