6448
Here we provide novel evidence that AG-490 potently inhibits the autokinase activity of JAK3 and tyrosine phosphorylation and DNA binding of signal transducer and activator of transcription 5a and 5b ( STAT5a/b ) .
 ( protein: JAK3, None) , ( protein: signal transducer and activator of transcription 5a and 5b ( STAT5a/b ), None) , ( protein: STAT5a/b, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: JAK3, None) , ( protein: signal transducer and activator of transcription 5a and 5b ( STAT5a/b ), None) , ( protein: STAT5a/b, None) 