3081
Lipopolysaccharide is one of the most potent trigger substances for monocytes and macrophages causing secretion of inflammatory mediators such as tumor necrosis factor and interleukin-1 .
 ( protein: interleukin-1, None) , ( protein: inflammatory mediators, None) , ( protein: tumor necrosis factor, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: interleukin-1, None) , ( protein: inflammatory mediators, None) , ( protein: tumor necrosis factor, None) 