1159
DESIGN: We reviewed the medical records of four patients, who were seen by us between July 2000 and February 2004 for sudden onset of a central neurological syndrome within days of intrathecal MTX.
 ( adverse event: intrathecal ,  medical records of four patients: Subject, four: Subject.Population, a central neurological syndrome: Effect, MTX: Treatment, MTX: Treatment.Drug, within days: Treatment.Time_elapsed) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: intrathecal ,  medical records of four patients: Subject, four: Subject.Population, a central neurological syndrome: Effect, MTX: Treatment, MTX: Treatment.Drug, within days: Treatment.Time_elapsed) 