10918
Together, these data demonstrate that the IL-4R alpha cytoplasmic domain is sufficient to activate JAK-1 and STAT6 and to induce expression of IL-4 target genes , thus identifying a mechanism by which IL-4 signaling can proceed in the absence of JAK-3 and gamma(c) .
 ( protein: IL-4, None) , ( protein: STAT6, None) , ( protein: JAK-3, None) , ( protein: gamma(c), None) , ( protein: IL-4, None) , ( protein: JAK-1, None) , ( protein: IL-4R alpha cytoplasmic domain, None) , ( DNA: IL-4 target genes, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-4, None) , ( protein: STAT6, None) , ( protein: JAK-3, None) , ( protein: gamma(c), None) , ( protein: IL-4, None) , ( protein: JAK-1, None) , ( protein: IL-4R alpha cytoplasmic domain, None) , ( DNA: IL-4 target genes, None) 