4852
CNI-1493 blocked neither the lipopolysaccharide (LPS)-induced increases in the expression of TNF mRNA nor the translocation of nuclear factor NF-kappa B to the nucleus in macrophages activated by 15 min of LPS stimulation , indicating that CNI-1493 does not interfere with early NF-kappa B -mediated transcriptional regulation of TNF .
 ( protein: TNF, None) , ( protein: NF-kappa B, None) , ( RNA: TNF mRNA, None) , ( protein: TNF, None) , ( protein: nuclear factor NF-kappa B, None) , ( cell type: macrophages, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: TNF, None) , ( protein: NF-kappa B, None) , ( RNA: TNF mRNA, None) , ( protein: TNF, None) , ( protein: nuclear factor NF-kappa B, None) , ( cell type: macrophages, None) 