8645
In conclusion, three different cell-specific pathways lead to NF-kappaB activation by IL-1beta : a pathway dependent on ROI production by 5-LOX in lymphoid cells , an ROI- and 5-LOX -independent pathway in epithelial cells , and a pathway requiring ROI production by NADPH oxidase in monocytic cells .
 ( protein: 5-LOX, None) , ( cell type: lymphoid cells, None) , ( protein: IL-1beta, None) , ( protein: NADPH oxidase, None) , ( protein: NF-kappaB, None) , ( cell type: epithelial cells, None) , ( protein: 5-LOX, None) , ( cell type: monocytic cells, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: 5-LOX, None) , ( cell type: lymphoid cells, None) , ( protein: IL-1beta, None) , ( protein: NADPH oxidase, None) , ( protein: NF-kappaB, None) , ( cell type: epithelial cells, None) , ( protein: 5-LOX, None) , ( cell type: monocytic cells, None) 