4805
The expression of p45 mRNA in the neutrophils declined rapidly after transfer of the cells to in vitro culture and G-CSF could not sustain the expression from the down-regulation, suggesting the E2 may also participate in the regulation of neutrophil-specific gene expression .
 ( protein: E2, None) , ( protein: p45, None) , ( cell type: neutrophils, None) , ( RNA: p45 mRNA, None) , ( protein: G-CSF, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: E2, None) , ( protein: p45, None) , ( cell type: neutrophils, None) , ( RNA: p45 mRNA, None) , ( protein: G-CSF, None) 