12645
As a step toward elucidating the pathophysiological background of the so-called glucose toxicity to pancreatic beta cells , we induced glycation in HIT-T15 cells using a sugar with strong deoxidizing activity, D-ribose , and examined the effects on insulin gene transcription .
 ( cell type: HIT-T15 cells, None) , ( cell type: pancreatic beta cells, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: HIT-T15 cells, None) , ( cell type: pancreatic beta cells, None) 