14685
Strikingly, costimulation with EC results in a dramatic increase (up to 15-fold) in the c-Fos content of AP-1 .
 ( protein: c-Fos, None) , ( protein: AP-1, None) , ( cell type: EC, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: c-Fos, None) , ( protein: AP-1, None) , ( cell type: EC, None) 