2735
The transmembrane domains are well conserved, but there is striking sequence divergence of the carboxy-terminal cytoplasmic domain essential for B-cell immortalization and interaction with the tumor necrosis factor receptor signaling pathway .
 ( cell type: B-cell, None) , ( protein: tumor necrosis factor receptor, None) , ( protein: carboxy-terminal cytoplasmic domain, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: B-cell, None) , ( protein: tumor necrosis factor receptor, None) , ( protein: carboxy-terminal cytoplasmic domain, None) 