7766
Targeted mutational analysis demonstrated that a tandem NF-kappa B /Rel binding motif is critical for the gamma 3 ECS responsiveness to both CD40L and IL-4 , while a STAT-6-binding site is additionally required for IL-4 inducibility .
 ( protein: NF-kappa B, None) , ( DNA: STAT-6-binding site, None) , ( DNA: gamma 3 ECS, None) , ( protein: CD40L, None) , ( protein: IL-4, None) , ( protein: IL-4, None) , ( DNA: NF-kappa B /Rel binding motif, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: NF-kappa B, None) , ( DNA: STAT-6-binding site, None) , ( DNA: gamma 3 ECS, None) , ( protein: CD40L, None) , ( protein: IL-4, None) , ( protein: IL-4, None) , ( DNA: NF-kappa B /Rel binding motif, None) 