4456
The discovery of these signaling pathways has led to important new insights into their role in lymphocyte maturation , as it has emerged that mutations in the genes encoding both gamma c and JAK3 result in similar forms of severe combined immunodeficiency ( SCID ).
 ( protein: gamma c, None) , ( protein: JAK3, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: gamma c, None) , ( protein: JAK3, None) 