12869
However, in contrast to the wild-type endotoxin, it failed to induce significant production of tumor necrosis factor-alpha and macrophage inflammatory protein-1alpha by monocytes and did not induce the phosphorylation and nuclear translocation of mitogen-activated protein kinase .
 ( cell type: monocytes, None) , ( protein: mitogen-activated protein kinase, None) , ( protein: tumor necrosis factor-alpha, None) , ( protein: macrophage inflammatory protein-1alpha, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: monocytes, None) , ( protein: mitogen-activated protein kinase, None) , ( protein: tumor necrosis factor-alpha, None) , ( protein: macrophage inflammatory protein-1alpha, None) 