10860
These results suggest that homodimerization of the IL-4Ralpha chain is sufficient to transduce Jak1 -dependent intracellular signals that lead to IgE isotype switching .
 ( protein: Jak1, None) , ( protein: IgE isotype, None) , ( protein: IL-4Ralpha chain, None) , ( protein: IL-4Ralpha, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: Jak1, None) , ( protein: IgE isotype, None) , ( protein: IL-4Ralpha chain, None) , ( protein: IL-4Ralpha, None) 