2163
Several human myeloid leukemia cell lines growing in vitro can be induced to differentiate to more mature monocyte/macrophage-like cells by treatment with protein kinase C -activating phorbol esters , such as PMA .
 ( cell line: human myeloid leukemia cell lines, None) , ( cell type: monocyte/macrophage-like cells, None) , ( protein: protein kinase C, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell line: human myeloid leukemia cell lines, None) , ( cell type: monocyte/macrophage-like cells, None) , ( protein: protein kinase C, None) 