5076
These observations suggest that PMA exerts its inhibitory effects by activation of a tyrosine phosphatase which selectively regulates Tyk2 but not Jak1 activity .
 ( protein: Jak1, None) , ( protein: Tyk2, None) , ( protein: tyrosine phosphatase, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: Jak1, None) , ( protein: Tyk2, None) , ( protein: tyrosine phosphatase, None) 