7280
Furthermore, expression of SHP-1 phosphatase which is a negative regulator of cytokine receptor signaling , was lost in most IL-2 independent cell lines (3/4) but not in the leukemic ATLL cells (0/3).
 ( protein: cytokine receptor, None) , ( cell line: IL-2 independent cell lines, None) , ( cell type: ATLL cells, None) , ( protein: SHP-1 phosphatase, None) , ( protein: IL-2, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: cytokine receptor, None) , ( cell line: IL-2 independent cell lines, None) , ( cell type: ATLL cells, None) , ( protein: SHP-1 phosphatase, None) , ( protein: IL-2, None) 