6134
Whereas the CRE site was essential in mediating the negative activity of the upstream regulatory region in Jurkat but not in HeLa cells , mutation of the Sp1/AP-2 site decreased promoter activity in both cell lines.
 ( DNA: Sp1/AP-2 site, None) , ( DNA: upstream regulatory region, None) , ( cell line: HeLa cells, None) , ( cell line: Jurkat, None) , ( DNA: CRE site, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: Sp1/AP-2 site, None) , ( DNA: upstream regulatory region, None) , ( cell line: HeLa cells, None) , ( cell line: Jurkat, None) , ( DNA: CRE site, None) 