5484
These results indicate that IL-10 , in addition to down-regulating the cellular immune response to HIV-1 , may also play a role in TNF-alpha -mediated activation of HIV-1 replication in the monocyte/macrophage lineage .
 ( protein: TNF-alpha, None) , ( protein: IL-10, None) , ( cell type: monocyte/macrophage lineage, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: TNF-alpha, None) , ( protein: IL-10, None) , ( cell type: monocyte/macrophage lineage, None) 