7759
These findings support a pathway by which LPS stimulation of neutrophils results in activation of MKK3 , which in turn activates p38alpha MAPk , ultimately regulating adhesion, NF-kappaB activation , enhanced gene expression of TNF-alpha , and regulation of TNF-alpha synthesis .
 ( protein: TNF-alpha, None) , ( protein: MKK3, None) , ( protein: NF-kappaB, None) , ( protein: p38alpha MAPk, None) , ( cell type: neutrophils, None) , ( protein: p38alpha, None) , ( protein: TNF-alpha, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: TNF-alpha, None) , ( protein: MKK3, None) , ( protein: NF-kappaB, None) , ( protein: p38alpha MAPk, None) , ( cell type: neutrophils, None) , ( protein: p38alpha, None) , ( protein: TNF-alpha, None) 