1048
The administration of "sweet spirits of nitre" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol) was followed by acute methemoglobinemia and severe anoxic metabolic acidosis in infant twins, Methylene blue administration reversed methemoglobinemia in both, but one twin died from the consequences of hypoxemia.
 ( adverse event: followed ,  infant twins: Subject, infant: Subject.Age, acute methemoglobinemia and severe anoxic metabolic acidosis: Effect, "sweet spirits of nitre" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol): Treatment, sweet spirits of nitre: Treatment.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: followed ,  infant twins: Subject, infant: Subject.Age, acute methemoglobinemia and severe anoxic metabolic acidosis: Effect, "sweet spirits of nitre" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol): Treatment, sweet spirits of nitre: Treatment.Drug) 