5147
The role of alterations of the MTS1 tumor suppressor gene on chromosome 9p21 , which encodes p16 , the inhibitor of cyclin-dependent-kinase- 4 and 6 , in tumorigenesis is not yet clear.
 ( DNA: chromosome 9p21, None) , ( DNA: MTS1 tumor suppressor gene, None) , ( protein: p16, None) , ( DNA: MTS1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: chromosome 9p21, None) , ( DNA: MTS1 tumor suppressor gene, None) , ( protein: p16, None) , ( DNA: MTS1, None) 