4697
While Jurkat cells both secrete and respond to IFN-gamma in an autocrine loop , it seems likely that the responding cells may differ from those synthesizing this cytokine in the mononuclear cell cultures in the light of the recent report that Th1 cells lack the IFN-gamma receptor chain necessary for activation of STAT1 (Pernis, A., Gupta, S., Gollob, K.J., Garfein, E., Coffman, R.L., Schindler, C., and Rothman, P., Science 1995. 269:245).
 ( protein: cytokine, None) , ( protein: IFN-gamma, None) , ( cell line: Th1 cells, None) , ( cell line: Jurkat cells, None) , ( cell line: mononuclear cell cultures, None) , ( protein: STAT1, None) , ( protein: IFN-gamma, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: cytokine, None) , ( protein: IFN-gamma, None) , ( cell line: Th1 cells, None) , ( cell line: Jurkat cells, None) , ( cell line: mononuclear cell cultures, None) , ( protein: STAT1, None) , ( protein: IFN-gamma, None) 