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A 56-year-old woman with scleroderma developed rapidly progressive glomerulonephritis with epithelial crescents associated with hemoptysis after 27 months of D-penicillamine therapy and a cumulative dose of 1,200 g.
 ( adverse event: developed ,  A 56-year-old woman with scleroderma: Subject, 56-year-old: Subject.Age, woman: Subject.Gender, rapidly progressive glomerulonephritis with epithelial crescents associated with hemoptysis: Effect, 27 months of D-penicillamine therapy and a cumulative dose of 1,200 g.: Treatment, scleroderma: Treatment.Disorder, 27 months: Treatment.Time_elapsed, D-penicillamine: Treatment.Drug, 1,200 g.: Treatment.Dosage) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  A 56-year-old woman with scleroderma: Subject, 56-year-old: Subject.Age, woman: Subject.Gender, rapidly progressive glomerulonephritis with epithelial crescents associated with hemoptysis: Effect, 27 months of D-penicillamine therapy and a cumulative dose of 1,200 g.: Treatment, scleroderma: Treatment.Disorder, 27 months: Treatment.Time_elapsed, D-penicillamine: Treatment.Drug, 1,200 g.: Treatment.Dosage) 