12094
Deregulated TCR -mediated responses and the fast kinetics of tumor development in these mutant thymocytes implicate Ikaros as a central tumor suppressor gene for the T cell lineage .
 ( cell type: T cell lineage, None) , ( cell type: mutant thymocytes, None) , ( protein: TCR, None) , ( DNA: central tumor suppressor gene, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: T cell lineage, None) , ( cell type: mutant thymocytes, None) , ( protein: TCR, None) , ( DNA: central tumor suppressor gene, None) 