7503
Our findings demonstrate that p38 MAPK 1) plays an important role in signal integration during costimulation of primary mouse T cells , 2) may be involved in the induction of c-Jun activation and augmentation of AP-1 transcriptional activity , and 3) regulates whether T cells enter a state of functional unresponsiveness .
 ( cell type: T cells, None) , ( protein: c-Jun, None) , ( cell type: primary mouse T cells, None) , ( protein: AP-1, None) , ( protein: p38 MAPK, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: T cells, None) , ( protein: c-Jun, None) , ( cell type: primary mouse T cells, None) , ( protein: AP-1, None) , ( protein: p38 MAPK, None) 