3963
Upon recurrence, however, the tumors sustained either deletion of p16 alone or codeletion of both p16 and p15 or amplification of CDK4 .
 ( protein: CDK4, None) , ( protein: p16, None) , ( protein: p16, None) , ( protein: p15, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: CDK4, None) , ( protein: p16, None) , ( protein: p16, None) , ( protein: p15, None) 