3162
Mutations in this site which eliminate PU.1 binding decrease M-CSF receptor promoter activity significantly in macrophage cell lines only.
 ( protein: M-CSF, None) , ( cell line: macrophage cell lines, None) , ( protein: PU.1, None) , ( protein: M-CSF receptor, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: M-CSF, None) , ( cell line: macrophage cell lines, None) , ( protein: PU.1, None) , ( protein: M-CSF receptor, None) 