9149
By using PD-98059 and SB203580 , two potent and selective inhibitors of MEK1 (a kinase upstream of ERK1/2 ) and p38 , respectively, we have demonstrated that both ERK1/2 and p38 cascades play a key role in the production of IL-8 by monocytes and PMN stimulated with bacterial fractions .
 ( protein: kinase, None) , ( cell type: PMN, None) , ( protein: IL-8, None) , ( protein: p38, None) , ( protein: ERK1/2, None) , ( cell type: monocytes, None) , ( protein: MEK1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: kinase, None) , ( cell type: PMN, None) , ( protein: IL-8, None) , ( protein: p38, None) , ( protein: ERK1/2, None) , ( cell type: monocytes, None) , ( protein: MEK1, None) 