5438
Because surfactant downregulated inflammatory cytokine production similarly in both normal human alveolar macrophages and the THP-1 cell line , we used this cell line to investigate whether surfactant affected transcriptional mechanisms .
 ( protein: inflammatory cytokine, None) , ( cell line: cell line, None) , ( cell line: THP-1 cell line, None) , ( cell type: normal human alveolar macrophages, None) , ( cell type: macrophages, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: inflammatory cytokine, None) , ( cell line: cell line, None) , ( cell line: THP-1 cell line, None) , ( cell type: normal human alveolar macrophages, None) , ( cell type: macrophages, None) 