11963
In order to investigate the nature of the A6H mAb costimulus at the transcriptional level we have examined induction of the transcription factors OCT-1 , AP-1 and NF-kappa B which are known to be transcriptional regulators of several cytokine and cytokine receptor genes, including the IL-2 and IL-2R genes .
 ( protein: cytokine, None) , ( protein: NF-kappa B, None) , ( protein: cytokine, None) , ( protein: transcription factors, None) , ( protein: A6H mAb, None) , ( protein: transcriptional regulators, None) , ( protein: OCT-1, None) , ( protein: AP-1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: cytokine, None) , ( protein: NF-kappa B, None) , ( protein: cytokine, None) , ( protein: transcription factors, None) , ( protein: A6H mAb, None) , ( protein: transcriptional regulators, None) , ( protein: OCT-1, None) , ( protein: AP-1, None) 