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We report on 7 patients (2 women, 5 men) with chronic renal failure, who developed under a high dosage of the new diuretic muzolimine (range 240 to 1440 mg per day) fatal neuromyeloencephalopathy.
 ( adverse event: developed ,  7 patients (2 women, 5 men) with chronic renal failure: Subject, chronic renal failure: Subject.Disorder, 7: Subject.Population, fatal neuromyeloencephalopathy: Effect, a high dosage of the new diuretic muzolimine (range 240 to 1440 mg per day): Treatment, diuretic muzolimine: Treatment.Drug, per day: Treatment.Freq, range 240 to 1440 mg: Treatment.Dosage) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  7 patients (2 women, 5 men) with chronic renal failure: Subject, chronic renal failure: Subject.Disorder, 7: Subject.Population, fatal neuromyeloencephalopathy: Effect, a high dosage of the new diuretic muzolimine (range 240 to 1440 mg per day): Treatment, diuretic muzolimine: Treatment.Drug, per day: Treatment.Freq, range 240 to 1440 mg: Treatment.Dosage) 