977
A patient with chronic myeloid leukaemia treated with busulphan for 4-5 years, developed signs of busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice.
 ( adverse event: developed ,  A patient with chronic myeloid leukaemia: Subject, busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice: Effect, busulphan for 4-5 years: Treatment, 4-5 years: Treatment.Duration, busulphan: Treatment.Drug, chronic myeloid leukaemia: Treatment.Disorder) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  A patient with chronic myeloid leukaemia: Subject, busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice: Effect, busulphan for 4-5 years: Treatment, 4-5 years: Treatment.Duration, busulphan: Treatment.Drug, chronic myeloid leukaemia: Treatment.Disorder) 