2748
In ductal carcinomas , chromosome 1 alterations increased with histologic grade, DNA aneuploidy , loss of bcl-2 and high c-erb B-2 expression.
 ( DNA: chromosome 1, None) , ( protein: c-erb B-2, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: chromosome 1, None) , ( protein: c-erb B-2, None) 