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There was, however, a significant difference in the amounts of the nuclear protein , REF-1 (which regulates AP-1 DNA binding by altering the redox status of FOS and JUN proteins ), in alveolar macrophages compared with monocytes .
 ( protein: nuclear protein, None) , ( protein: JUN proteins, None) , ( protein: AP-1, None) , ( cell type: alveolar macrophages, None) , ( protein: REF-1, None) , ( protein: FOS, None) , ( cell type: monocytes, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: nuclear protein, None) , ( protein: JUN proteins, None) , ( protein: AP-1, None) , ( cell type: alveolar macrophages, None) , ( protein: REF-1, None) , ( protein: FOS, None) , ( cell type: monocytes, None) 