12826
In vivo studies indicated that CD3 -induced HSI phosphorylation was dependent upon both the Src family tyrosine kinase Lck and the tyrosine phosphatase CD45 , did not require MEK1 kinase activity , and was regulated by protein kinase C activation .
 ( protein: Lck, None) , ( protein: Src family tyrosine kinase, None) , ( protein: tyrosine phosphatase, None) , ( protein: protein kinase C, None) , ( protein: CD45, None) , ( protein: MEK1, None) , ( protein: HSI, None) , ( protein: CD3, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: Lck, None) , ( protein: Src family tyrosine kinase, None) , ( protein: tyrosine phosphatase, None) , ( protein: protein kinase C, None) , ( protein: CD45, None) , ( protein: MEK1, None) , ( protein: HSI, None) , ( protein: CD3, None) 