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We present two children with acute lymphocytic leukemia who developed leukoencephalopathy following administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy.
 ( adverse event: developed ,  two children with acute lymphocytic leukemia: Subject, two: Subject.Population, children: Subject.Age, leukoencephalopathy: Effect, administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy: Treatment, acute lymphocytic leukemia: Treatment.Disorder, intravenous: Treatment.Route, ara = C: Treatment.Drug, methotrexate: Treatment.Drug, ara = C: Combination.Drug, methotrexate: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  two children with acute lymphocytic leukemia: Subject, two: Subject.Population, children: Subject.Age, leukoencephalopathy: Effect, administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy: Treatment, acute lymphocytic leukemia: Treatment.Disorder, intravenous: Treatment.Route, ara = C: Treatment.Drug, methotrexate: Treatment.Drug, ara = C: Combination.Drug, methotrexate: Combination.Drug) 