4268
In the presence of 1 alpha,25(OH)2D3 , cellular activation associated with stimulation of such a progression appears to be sufficient for the up-regulation of VDR message and protein and necessary for the establishment of VDRE binding complexes and the induction of 24-hydroxylase message .
 ( protein: VDR, None) , ( DNA: VDRE, None) , ( protein: VDRE binding complexes, None) , ( protein: 24-hydroxylase, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: VDR, None) , ( DNA: VDRE, None) , ( protein: VDRE binding complexes, None) , ( protein: 24-hydroxylase, None) 