5472
The signal transduction events involved in gp120 -mediated enhancement of ICAM-1 appear to involve activation of both protein kinase C and tyrosine kinase , because inhibitors of protein kinase C and tyrosine kinase abrogate gp120 -mediated ICAM-1 expression in both astrocytes and microglia .
 ( protein: gp120, None) , ( protein: protein kinase C, None) , ( cell type: astrocytes, None) , ( protein: ICAM-1, None) , ( cell type: microglia, None) , ( protein: tyrosine kinase, None) , ( protein: ICAM-1, None) , ( protein: protein kinase C, None) , ( protein: gp120, None) , ( protein: tyrosine kinase, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: gp120, None) , ( protein: protein kinase C, None) , ( cell type: astrocytes, None) , ( protein: ICAM-1, None) , ( cell type: microglia, None) , ( protein: tyrosine kinase, None) , ( protein: ICAM-1, None) , ( protein: protein kinase C, None) , ( protein: gp120, None) , ( protein: tyrosine kinase, None) 