12687
Here, we show that loss of GATA-3 expression by developing Th1 cells requires IL-12 signaling through Stat4 and does not simply result from an absence of IL-4 .
 ( protein: IL-4, None) , ( protein: IL-12, None) , ( cell type: Th1 cells, None) , ( protein: GATA-3, None) , ( protein: Stat4, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-4, None) , ( protein: IL-12, None) , ( cell type: Th1 cells, None) , ( protein: GATA-3, None) , ( protein: Stat4, None) 