8900
This GAG also possesses immunomodulatory activity in vivo and can antagonize the capacity of IFN-gamma to induce class II MHC antigen expression , and to up-regulate intercellular adhesion molecule-1 , by cultured endothelial cells .
 ( protein: IFN-gamma, None) , ( protein: intercellular adhesion molecule-1, None) , ( cell line: cultured endothelial cells, None) , ( protein: class II MHC antigen, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IFN-gamma, None) , ( protein: intercellular adhesion molecule-1, None) , ( cell line: cultured endothelial cells, None) , ( protein: class II MHC antigen, None) 