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Since renal insufficiency was induced by AMPH and the other antifungal drugs were ineffective, daily administration of 200 mg of ITCZ was initiated, and the inflammatory signs and symptoms gradually subsided.
 ( potential therapeutic event: initiated,,  the inflammatory signs and symptoms gradually subsided.: Effect, daily administration of 200 mg of ITCZ: Treatment, renal insufficiency: Treatment.Disorder, 200 mg: Treatment.Dosage, daily administration: Treatment.Freq, ITCZ: Treatment.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( potential therapeutic event: initiated,,  the inflammatory signs and symptoms gradually subsided.: Effect, daily administration of 200 mg of ITCZ: Treatment, renal insufficiency: Treatment.Disorder, 200 mg: Treatment.Dosage, daily administration: Treatment.Freq, ITCZ: Treatment.Drug) 