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METHODS: A patient who developed dramatic, permanent vision loss after a 9-month course of treatment with ethambutol and isoniazid for pulmonary tuberculosis is presented.
 ( adverse event: after ,  A patient: Subject, permanent vision loss: Effect, 9-month course of treatment with ethambutol and isoniazid: Treatment, pulmonary tuberculosis: Treatment.Disorder, 9-month: Treatment.Time_elapsed, ethambutol: Treatment.Drug, isoniazid: Treatment.Drug, ethambutol: Combination.Drug, isoniazid: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: after ,  A patient: Subject, permanent vision loss: Effect, 9-month course of treatment with ethambutol and isoniazid: Treatment, pulmonary tuberculosis: Treatment.Disorder, 9-month: Treatment.Time_elapsed, ethambutol: Treatment.Drug, isoniazid: Treatment.Drug, ethambutol: Combination.Drug, isoniazid: Combination.Drug) 