313
In addition, integrin ligation leads to nuclear translocation of the p50 and p65 subunits of the NF-kappa B transcription factor , to activation of a reporter gene driven by a promoter containing NF-kappa B sites , and to increased levels of mRNAs for immediate-early genes , including the cytokine interleukin (IL)-1 beta .
 ( DNA: promoter, None) , ( DNA: reporter gene, None) , ( RNA: mRNAs, None) , ( protein: NF-kappa B transcription factor, None) , ( DNA: immediate-early genes, None) , ( DNA: NF-kappa B sites, None) , ( protein: p65 subunits, None) , ( protein: p50, None) , ( protein: cytokine interleukin (IL)-1 beta, None) , ( protein: integrin, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: promoter, None) , ( DNA: reporter gene, None) , ( RNA: mRNAs, None) , ( protein: NF-kappa B transcription factor, None) , ( DNA: immediate-early genes, None) , ( DNA: NF-kappa B sites, None) , ( protein: p65 subunits, None) , ( protein: p50, None) , ( protein: cytokine interleukin (IL)-1 beta, None) , ( protein: integrin, None) 