10347
We demonstrate that one target of this positive/negative regulation in vivo is the alpha4 integrin , which play a key role in normal hematopoiesis and function of mature leukocytes .
 ( cell type: mature leukocytes, None) , ( protein: alpha4 integrin, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: mature leukocytes, None) , ( protein: alpha4 integrin, None) 