9229
We now find that mutating two tyrosines to an isoleucine at the carboxyl end of the cytoplasmic tail cripples the ability of EBV to cause lymphoblastoid cell outgrowth , thereby marking a second transformation effector site , TES2 .
 ( protein: carboxyl end, None) , ( protein: cytoplasmic tail, None) , ( protein: TES2, None) , ( protein: transformation effector site, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: carboxyl end, None) , ( protein: cytoplasmic tail, None) , ( protein: TES2, None) , ( protein: transformation effector site, None) 