3937
Tyloxapol inhibits activation of the transcription factor nuclear factor-kappa B ( NK-kappa B ), reduces resting secretion of the cytokine interleukin-8 ( IL-8 ) in cultured human monocytes , and inhibits lipopolysaccharide ( LPS )-stimulated release of tumor necrosis factor-alpha ( TNF-alpha ), IL-1 beta , IL-6 , IL-8 , granulocyte-macrophage colony-stimulating factor ( GM-CSF ), and the eiconsanoids thromboxane A2 and leukotriene B4 ( LTB4 ).
 ( protein: IL-1 beta, None) , ( protein: GM-CSF, None) , ( protein: cytokine, None) , ( protein: TNF-alpha, None) , ( protein: NK-kappa B, None) , ( protein: IL-8, None) , ( protein: transcription factor nuclear factor-kappa B, None) , ( protein: interleukin-8, None) , ( cell line: cultured human monocytes, None) , ( protein: tumor necrosis factor-alpha, None) , ( protein: granulocyte-macrophage colony-stimulating factor, None) , ( protein: IL-6, None) , ( protein: IL-8, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-1 beta, None) , ( protein: GM-CSF, None) , ( protein: cytokine, None) , ( protein: TNF-alpha, None) , ( protein: NK-kappa B, None) , ( protein: IL-8, None) , ( protein: transcription factor nuclear factor-kappa B, None) , ( protein: interleukin-8, None) , ( cell line: cultured human monocytes, None) , ( protein: tumor necrosis factor-alpha, None) , ( protein: granulocyte-macrophage colony-stimulating factor, None) , ( protein: IL-6, None) , ( protein: IL-8, None) 