12512
We, therefore, conclude that signals generated by the convergence of the MAPK and the calcineurin /NFAT pathway are necessary and sufficient for the activation of the IL-2 promoter by Tpl-2 .
 ( DNA: IL-2 promoter, None) , ( protein: calcineurin, None) , ( protein: IL-2, None) , ( protein: /NFAT, None) , ( protein: Tpl-2, None) , ( protein: MAPK, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: IL-2 promoter, None) , ( protein: calcineurin, None) , ( protein: IL-2, None) , ( protein: /NFAT, None) , ( protein: Tpl-2, None) , ( protein: MAPK, None) 