5439
Specifically, we examined nuclear factor-kappa B ( NF-kappa B ) activation because it is crucial in transcriptional regulation of many inflammatory cytokine genes including TNF , IL-1 , and IL-6 .
 ( protein: inflammatory cytokine, None) , ( DNA: IL-1, None) , ( DNA: TNF, None) , ( protein: nuclear factor-kappa B, None) , ( DNA: IL-6, None) , ( protein: NF-kappa B, None) , ( DNA: inflammatory cytokine genes, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: inflammatory cytokine, None) , ( DNA: IL-1, None) , ( DNA: TNF, None) , ( protein: nuclear factor-kappa B, None) , ( DNA: IL-6, None) , ( protein: NF-kappa B, None) , ( DNA: inflammatory cytokine genes, None) 