7176
In EBV infection most of the changes, including the early induction of cyclin D2 , are dependent on expression of EBV genes , but an alteration in the E2F-4 profile was partly independent of viral gene expression , presumably occurring in response to signal transduction activated when the virus binds to its receptor, CD21 .
 ( DNA: EBV genes, None) , ( protein: CD21, None) , ( protein: cyclin D2, None) , ( protein: E2F-4, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: EBV genes, None) , ( protein: CD21, None) , ( protein: cyclin D2, None) , ( protein: E2F-4, None) 