6527
These results suggest that NF-kappaB activation is required for C5a -induced IL-8 gene expression and that this response is mediated primarily through a pertussis toxin -insensitive pathway .
 ( protein: NF-kappaB, None) , ( protein: IL-8, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: NF-kappaB, None) , ( protein: IL-8, None) 