2364
Furthermore, we confirmed the previous report that FK506 suppressed the PMA / ionomycin -induced activation through authentic kappa B site of immunoglobulin (Ig) gene , to which NF-kappa B binding was also decreased by FK506 , indicating that both IL-8 kappa B-like site and Ig kappa B site are FK506 -sensitive in spite of the difference of binding factors .
 ( DNA: kappa B site, None) , ( DNA: kappa B site, None) , ( protein: NF-kappa B, None) , ( DNA: IL-8 kappa B-like site, None) , ( protein: IL-8, None) , ( protein: binding factors, None) , ( DNA: immunoglobulin (Ig) gene, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: kappa B site, None) , ( DNA: kappa B site, None) , ( protein: NF-kappa B, None) , ( DNA: IL-8 kappa B-like site, None) , ( protein: IL-8, None) , ( protein: binding factors, None) , ( DNA: immunoglobulin (Ig) gene, None) 