11869
Reactive oxygen species ( ROS ) such as hydrogen peroxide serve as second messengers in the induction of the transcription factor NF-kappaB , and hence in the activation and replication of human immunodeficiency virus type 1 ( HIV-1 ) in human cells .
 ( protein: transcription factor, None) , ( cell type: human cells, None) , ( protein: NF-kappaB, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: transcription factor, None) , ( cell type: human cells, None) , ( protein: NF-kappaB, None) 