12870
These results suggest that 1) lipid A myristoyl fatty acid , although it is important for the induction of inflammatory cytokine production by human monocytes , is not necessary for the induction of Mn SOD , 2) endotoxin -mediated induction of Mn SOD and inflammatory cytokines are regulated, at least in part, through different signal transduction pathways , and 3) failure of the mutant endotoxin to induce tumor necrosis factor-alpha production is, at least in part, due to its inability to activate mitogen-activated protein kinase .
 ( cell type: human monocytes, None) , ( protein: cytokines, None) , ( protein: mutant endotoxin, None) , ( protein: endotoxin, None) , ( protein: tumor necrosis factor-alpha, None) , ( protein: mitogen-activated protein kinase, None) , ( protein: Mn SOD, None) , ( protein: Mn SOD, None) , ( protein: inflammatory cytokine, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: human monocytes, None) , ( protein: cytokines, None) , ( protein: mutant endotoxin, None) , ( protein: endotoxin, None) , ( protein: tumor necrosis factor-alpha, None) , ( protein: mitogen-activated protein kinase, None) , ( protein: Mn SOD, None) , ( protein: Mn SOD, None) , ( protein: inflammatory cytokine, None) 