2653
To demonstrate a direct link between changes in the phosphorylation pattern of I kappa B alpha with NF-kappa B activation , we immunoprecipitated I kappa B alpha after varying times of hypoxic exposure and found that its tyrosine phosphorylation status increased during hypoxic exposure .
 ( protein: NF-kappa B, None) , ( protein: I kappa B alpha, None) , ( protein: I kappa B alpha, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: NF-kappa B, None) , ( protein: I kappa B alpha, None) , ( protein: I kappa B alpha, None) 