8194
Although peripheral blood T cells are largely unresponsive to these cytokines without prior activation, a small subset of CD8+ T cells ( CD8+CD18bright ) is strongly activated by the combination of IL-12 and IL-2 .
 ( cell type: T cells, None) , ( protein: cytokines, None) , ( cell type: CD8+ T cells, None) , ( cell type: CD8+CD18bright, None) , ( protein: IL-2, None) , ( protein: IL-12, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: T cells, None) , ( protein: cytokines, None) , ( cell type: CD8+ T cells, None) , ( cell type: CD8+CD18bright, None) , ( protein: IL-2, None) , ( protein: IL-12, None) 