14318
Our studies demonstrate for the first time that CD3 antigen-derived signals and CD2 antigen -derived signals are synergistic in inducing the emergence of transcription factors that bind to the NF-AT1 , AP-1 , and NF-kB sites located in the promoter/enhancer region of the IL-2 gene.
 ( protein: IL-2, None) , ( protein: CD2 antigen, None) , ( DNA: promoter/enhancer region, None) , ( protein: transcription factors, None) , ( protein: CD3, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-2, None) , ( protein: CD2 antigen, None) , ( DNA: promoter/enhancer region, None) , ( protein: transcription factors, None) , ( protein: CD3, None) 