9894
Despite stimulation with LPS , disruption of the NF-kappaB signaling pathway in precursor B cells led to the loss of inducible Oct-2 DNA binding activity in vitro and the suppression of Oct-2 -directed transcription in vivo.
 ( protein: Oct-2, None) , ( protein: Oct-2, None) , ( cell type: precursor B cells, None) , ( protein: NF-kappaB, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: Oct-2, None) , ( protein: Oct-2, None) , ( cell type: precursor B cells, None) , ( protein: NF-kappaB, None) 