4664
Second messenger up-regulation of androgen receptor gene transcription is absent in androgen insensitive human prostatic carcinoma cell lines , PC-3 and DU-145 .
 ( cell line: androgen insensitive human prostatic carcinoma cell lines, None) , ( cell line: DU-145, None) , ( DNA: androgen receptor gene, None) , ( cell line: PC-3, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell line: androgen insensitive human prostatic carcinoma cell lines, None) , ( cell line: DU-145, None) , ( DNA: androgen receptor gene, None) , ( cell line: PC-3, None) 