12147
The differentiation of naive T-helper (Th) cells into cytokine -secreting effector Th cells requires exposure to multiple signals, including exogenous cytokines .
 ( cell type: cytokine -secreting effector Th cells, None) , ( cell type: naive T-helper (Th) cells, None) , ( protein: cytokine, None) , ( protein: exogenous cytokines, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: cytokine -secreting effector Th cells, None) , ( cell type: naive T-helper (Th) cells, None) , ( protein: cytokine, None) , ( protein: exogenous cytokines, None) 