13490
CONCLUSION: These results indicate that (1) IgE production in asthma and HIE usually is associated with elevated levels of IL-4 , but not IL-13 , in the peripheral blood; (2) the increased sera IL-4 levels in asthma and HIE are not sufficient to induce Stat6 activation in PBMCs ; and (3) evidence of switch recombination to epsilon may be detected in isolated cases of elevated IgE .
 ( protein: IgE, None) , ( protein: IL-13, None) , ( protein: IL-4, None) , ( cell type: PBMCs, None) , ( protein: IL-4, None) , ( protein: IgE, None) , ( protein: Stat6, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IgE, None) , ( protein: IL-13, None) , ( protein: IL-4, None) , ( cell type: PBMCs, None) , ( protein: IL-4, None) , ( protein: IgE, None) , ( protein: Stat6, None) 