12392
Second, in contrast to recent results on human cell lines , CIITA is not critically involved in the IFN-gamma -induced up-regulation of MHC class I genes .
 ( cell line: human cell lines, None) , ( protein: CIITA, None) , ( protein: IFN-gamma, None) , ( DNA: MHC class I genes, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell line: human cell lines, None) , ( protein: CIITA, None) , ( protein: IFN-gamma, None) , ( DNA: MHC class I genes, None) 