12264
A point mutation of a potential phosphatidylinositol 3-kinase ( PI3-K ) binding site ( Y731EAM to Y731EAC ) in 70Z/3 disrupted the association of PI3-K with 70Z/3 , but did not reduce the induction of NFAT activity , suggesting that the interaction between Cbl and PI3-K is not required in the 70Z/3 -mediated induction of NFAT .
 ( protein: PI3-K, None) , ( protein: PI3-K, None) , ( protein: 70Z/3, None) , ( protein: PI3-K, None) , ( protein: 70Z/3, None) , ( protein: Cbl, None) , ( DNA: Y731EAM, None) , ( DNA: phosphatidylinositol 3-kinase ( PI3-K ) binding site, None) , ( protein: NFAT, None) , ( protein: 70Z/3, None) , ( protein: phosphatidylinositol 3-kinase, None) , ( protein: NFAT, None) , ( DNA: Y731EAC, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: PI3-K, None) , ( protein: PI3-K, None) , ( protein: 70Z/3, None) , ( protein: PI3-K, None) , ( protein: 70Z/3, None) , ( protein: Cbl, None) , ( DNA: Y731EAM, None) , ( DNA: phosphatidylinositol 3-kinase ( PI3-K ) binding site, None) , ( protein: NFAT, None) , ( protein: 70Z/3, None) , ( protein: phosphatidylinositol 3-kinase, None) , ( protein: NFAT, None) , ( DNA: Y731EAC, None) 