4180
Expression of the human immunodeficiency virus type 1 ( HIV ) protease in cultured cells leads to apoptosis , preceded by cleavage of bcl-2 , a key negative regulator of cell death.
 ( protein: bcl-2, None) , ( cell line: cultured cells, None) , ( protein: human immunodeficiency virus type 1 ( HIV ) protease, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: bcl-2, None) , ( cell line: cultured cells, None) , ( protein: human immunodeficiency virus type 1 ( HIV ) protease, None) 