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Although the t-AML developed following oral etoposide therapy, the child had previously received high-dose, multiagent chemotherapy, and rearrangement of the MLL gene was not demonstrated.
 ( adverse event: developed ,  the child: Subject, child: Subject.Age, the t-AML: Effect, oral etoposide therapy: Treatment, high-dose, multiagent chemotherapy: Treatment, etoposide: Treatment.Drug, chemotherapy: Treatment.Drug, oral: Treatment.Route, high-dose: Treatment.Dosage, chemotherapy: Combination.Drug, etoposide: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  the child: Subject, child: Subject.Age, the t-AML: Effect, oral etoposide therapy: Treatment, high-dose, multiagent chemotherapy: Treatment, etoposide: Treatment.Drug, chemotherapy: Treatment.Drug, oral: Treatment.Route, high-dose: Treatment.Dosage, chemotherapy: Combination.Drug, etoposide: Combination.Drug) 