11439
Interleukin-2 ( IL-2 ) promoter activity stimulated by cross-linking of CD2 , TCR /CD3, and CD28 with antibodies was significantly reduced by transient expression of an Itk mutant lacking the kinase activity .
 ( protein: IL-2, None) , ( protein: CD28, None) , ( protein: Itk, None) , ( protein: Itk mutant, None) , ( protein: TCR, None) , ( protein: CD2, None) , ( protein: antibodies, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-2, None) , ( protein: CD28, None) , ( protein: Itk, None) , ( protein: Itk mutant, None) , ( protein: TCR, None) , ( protein: CD2, None) , ( protein: antibodies, None) 