2253
The hydrophobic domain is homologous to three yeast polypeptides , suggesting that this higher eukaryotic gene could have evolved from recombination between a gene that encoded a soluble nuclear protein and a membrane protein gene similar to those in yeast .
 ( protein: hydrophobic domain, None) , ( protein: membrane protein, None) , ( DNA: membrane protein gene, None) , ( DNA: higher eukaryotic gene, None) , ( protein: soluble nuclear protein, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: hydrophobic domain, None) , ( protein: membrane protein, None) , ( DNA: membrane protein gene, None) , ( DNA: higher eukaryotic gene, None) , ( protein: soluble nuclear protein, None) 