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In contrast to the purely enhancer-dependent effect of cytokines such as TNF on the activity of the HIV regulatory region ( LTR ), we observed that okadaic acid ( OKA ) activates HIV transcription through both the enhancer, responding to the factor NF-kappa B , and the promoter domain of the LTR .
 ( DNA: LTR, None) , ( DNA: HIV regulatory region, None) , ( protein: NF-kappa B, None) , ( protein: cytokines, None) , ( DNA: LTR, None) , ( DNA: promoter domain, None) , ( protein: TNF, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: LTR, None) , ( DNA: HIV regulatory region, None) , ( protein: NF-kappa B, None) , ( protein: cytokines, None) , ( DNA: LTR, None) , ( DNA: promoter domain, None) , ( protein: TNF, None) 