6004
The DNA change , 2418delA , is considered a mutation that inactivated one BRCA1 allele because it caused a frameshift and generation of a premature stop codon , resulting in synthesis of a truncated peptide as evidenced by an in vitro protein truncation test.
 ( DNA: BRCA1, None) , ( DNA: premature stop codon, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: BRCA1, None) , ( DNA: premature stop codon, None) 