8505
These data suggest that CD19 -mediated signal transduction activates different transcription factors at juxtaposed stages of B cell development that may culminate in the activation or suppression of distinct sets of genes .
 ( protein: CD19, None) , ( protein: transcription factors, None) , ( DNA: genes, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: CD19, None) , ( protein: transcription factors, None) , ( DNA: genes, None) 