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Since SS is a clinical diagnosis, heightened clinician awareness of the possibility of SS among patients receiving SSRI or mirtazapine in combination with opioids may lead to earlier detection and avoidance of potentially lethal consequences.
 ( adverse event: lead to ,  patients: Subject, potentially lethal consequences: Effect, SSRI or mirtazapine in combination with opioids: Treatment, SSRI: Treatment.Drug, mirtazapine: Treatment.Drug, opioids: Treatment.Drug, mirtazapine: Combination.Drug, opioids: Combination.Drug, SSRI: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: lead to ,  patients: Subject, potentially lethal consequences: Effect, SSRI or mirtazapine in combination with opioids: Treatment, SSRI: Treatment.Drug, mirtazapine: Treatment.Drug, opioids: Treatment.Drug, mirtazapine: Combination.Drug, opioids: Combination.Drug, SSRI: Combination.Drug) 