4566
IL-4 also stimulated all three kinases and substrates, but unlike in immune cells , IL-4 did not involve JAK3 activation for its signaling in colon cancer cell lines .
 ( cell type: immune cells, None) , ( cell line: colon cancer cell lines, None) , ( protein: kinases, None) , ( protein: IL-4, None) , ( protein: JAK3, None) , ( protein: IL-4, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: immune cells, None) , ( cell line: colon cancer cell lines, None) , ( protein: kinases, None) , ( protein: IL-4, None) , ( protein: JAK3, None) , ( protein: IL-4, None) 