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A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency who developed a syringotropic hypersensitivity reaction after 9 months of therapy with infliximab and leflunomide is described.
 ( adverse event: developed ,  A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency: Subject, 17-year-old: Subject.Age, boy: Subject.Gender, alpha-1 antitrypsin deficiency: Subject.Disorder, syringotropic hypersensitivity reaction: Effect, 9 months of therapy with infliximab and leflunomide: Treatment, refractory psoriatic arthritis: Treatment.Disorder, infliximab: Treatment.Drug, leflunomide: Treatment.Drug, 9 months: Treatment.Duration, infliximab: Combination.Drug, leflunomide: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency: Subject, 17-year-old: Subject.Age, boy: Subject.Gender, alpha-1 antitrypsin deficiency: Subject.Disorder, syringotropic hypersensitivity reaction: Effect, 9 months of therapy with infliximab and leflunomide: Treatment, refractory psoriatic arthritis: Treatment.Disorder, infliximab: Treatment.Drug, leflunomide: Treatment.Drug, 9 months: Treatment.Duration, infliximab: Combination.Drug, leflunomide: Combination.Drug) 