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We studied the role of the immediate early gene c-jun in cell proliferation and phorbol 12-myristate 13-acetate ( PMA )-induced differentiation in U937 human monoblastic cells , using c-jun -specific antisense (AS) phosphorothioate oligonucleotides .
 ( DNA: c-jun, None) , ( DNA: c-jun, None) , ( DNA: immediate early gene, None) , ( cell line: U937 human monoblastic cells, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: c-jun, None) , ( DNA: c-jun, None) , ( DNA: immediate early gene, None) , ( cell line: U937 human monoblastic cells, None) 