8323
Thus HIV-1 gp41 -induced IL-10 up-regulation in monocytes may not involve NF-kappaB , MAPK , or PI 3-kinase activation , but rather may operate through activation of adenylate cyclase and pertussis-toxin-sensitive Gi/Go protein to effect p70(S6)-kinase activation .
 ( protein: MAPK, None) , ( protein: adenylate cyclase, None) , ( protein: PI 3-kinase, None) , ( protein: IL-10, None) , ( cell type: monocytes, None) , ( protein: NF-kappaB, None) , ( protein: pertussis-toxin-sensitive Gi/Go protein, None) , ( protein: gp41, None) , ( protein: p70(S6)-kinase, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: MAPK, None) , ( protein: adenylate cyclase, None) , ( protein: PI 3-kinase, None) , ( protein: IL-10, None) , ( cell type: monocytes, None) , ( protein: NF-kappaB, None) , ( protein: pertussis-toxin-sensitive Gi/Go protein, None) , ( protein: gp41, None) , ( protein: p70(S6)-kinase, None) 