6834
In all patients a marked decrease in IL-2 -producing cells and a significant increase in well-differentiated Th1 cells that produced IFN-gamma but not IL-2 were evident after priming with anti-CD3 and anti-CD28 .
 ( cell type: Th1 cells, None) , ( protein: anti-CD3, None) , ( protein: IFN-gamma, None) , ( protein: IL-2, None) , ( protein: IL-2, None) , ( cell type: IL-2 -producing cells, None) , ( protein: anti-CD28, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: Th1 cells, None) , ( protein: anti-CD3, None) , ( protein: IFN-gamma, None) , ( protein: IL-2, None) , ( protein: IL-2, None) , ( cell type: IL-2 -producing cells, None) , ( protein: anti-CD28, None) 