318
These observations indicate that the Syk tyrosine kinase may be an important component of an integrin signaling pathway in monocytic cells , leading to activation of NF-kappa B and to increased levels of cytokine messages .
 ( protein: integrin, None) , ( protein: Syk, None) , ( cell type: monocytic cells, None) , ( protein: NF-kappa B, None) , ( protein: cytokine, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: integrin, None) , ( protein: Syk, None) , ( cell type: monocytic cells, None) , ( protein: NF-kappa B, None) , ( protein: cytokine, None) 