5436
We previously demonstrated that both synthetic ( Exosurf ) and modified natural surfactant ( Survanta ) downregulated endotoxin-stimulated inflammatory c ytokine mRNA levels and protein products ( tumor necrosis factor-alpha [TNF], interleukin-1-beta [ IL-1 ], interleukin-6 [ IL-6 ]) in human alveolar macrophages .
 ( protein: IL-6, None) , ( protein: interleukin-1-beta, None) , ( protein: interleukin-6, None) , ( cell type: macrophages, None) , ( protein: IL-1, None) , ( protein: protein products, None) , ( cell type: human alveolar macrophages, None) , ( RNA: inflammatory c ytokine mRNA, None) , ( protein: tumor necrosis factor-alpha, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IL-6, None) , ( protein: interleukin-1-beta, None) , ( protein: interleukin-6, None) , ( cell type: macrophages, None) , ( protein: IL-1, None) , ( protein: protein products, None) , ( cell type: human alveolar macrophages, None) , ( RNA: inflammatory c ytokine mRNA, None) , ( protein: tumor necrosis factor-alpha, None) 