3990
Altogether, these results suggest that ATRA /9-cis RA may play a key role in FL hematopoiesis via a dual effect hypothetically mediated by interaction with the RAR/RXR heterodimer , ie, inhibition of HSC/ primitive HPC proliferation and induction of CFU-GEMM/ BFU-E/CFU-M shift from the multipotent / erythroid / monocytic to the granulocytic-neutrophilic differentiation program .
 ( cell line: HSC/ primitive HPC, None) , ( protein: RAR/RXR heterodimer, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell line: HSC/ primitive HPC, None) , ( protein: RAR/RXR heterodimer, None) 