7562
We investigated the mechanisms by which proinflammatory mediator , thrombin , released during intravascular coagulation and tissue injury , induces ICAM-1 ( CD54 ) expression in endothelial cells .
 ( protein: CD54, None) , ( protein: proinflammatory mediator, None) , ( protein: thrombin, None) , ( cell type: endothelial cells, None) , ( protein: ICAM-1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: CD54, None) , ( protein: proinflammatory mediator, None) , ( protein: thrombin, None) , ( cell type: endothelial cells, None) , ( protein: ICAM-1, None) 