1544
A 65-year-old female patient presented with jaundice followed 2 days later by severe dyspnea and tachypnea which worsened when patient was lying flat, 1 week after the fourth dose of adalimumab.
 ( adverse event: presented ,  A 65-year-old female patient: Subject, 65-year-old: Subject.Age, female: Subject.Gender, jaundice followed 2 days later by severe dyspnea and tachypnea which worsened when patient was lying flat: Effect, 1 week after the fourth dose of adalimumab: Treatment, adalimumab: Treatment.Drug, 1 week after: Treatment.Time_elapsed, fourth dose: Treatment.Dosage) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: presented ,  A 65-year-old female patient: Subject, 65-year-old: Subject.Age, female: Subject.Gender, jaundice followed 2 days later by severe dyspnea and tachypnea which worsened when patient was lying flat: Effect, 1 week after the fourth dose of adalimumab: Treatment, adalimumab: Treatment.Drug, 1 week after: Treatment.Time_elapsed, fourth dose: Treatment.Dosage) 