7185
Further, CTLA-4 engagement inhibited progression through the cell cycle by inhibiting the production of cyclin D3 , cyclin-dependent kinase (cdk)4 , and cdk6 when the T cells were stimulated with anti-CD3/ CD28 and with anti-CD3 alone.
 ( protein: (cdk)4, None) , ( protein: CD28, None) , ( protein: anti-CD3/ CD28, None) , ( protein: anti-CD3, None) , ( protein: cyclin D3, None) , ( protein: CTLA-4, None) , ( protein: cyclin-dependent kinase, None) , ( cell type: T cells, None) , ( protein: cdk6, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: (cdk)4, None) , ( protein: CD28, None) , ( protein: anti-CD3/ CD28, None) , ( protein: anti-CD3, None) , ( protein: cyclin D3, None) , ( protein: CTLA-4, None) , ( protein: cyclin-dependent kinase, None) , ( cell type: T cells, None) , ( protein: cdk6, None) 