8272
Several new functions of Ras , such as downregulation of major histocompatibility complex molecules , upregulation of certain cytokines , growth factors and degradative enzymes have been uncovered in the last decade.
 ( protein: cytokines, None) , ( protein: Ras, None) , ( protein: growth factors, None) , ( protein: degradative enzymes, None) , ( protein: major histocompatibility complex molecules, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: cytokines, None) , ( protein: Ras, None) , ( protein: growth factors, None) , ( protein: degradative enzymes, None) , ( protein: major histocompatibility complex molecules, None) 