6106
SHP1 -DeltaSH2 also inhibited events downstream of ZAP-70 and Syk , such as activation of the mitogen-activated protein kinase Erk2 and the transcriptional activation of the interleukin-2 gene .
 ( protein: mitogen-activated protein kinase, None) , ( protein: Erk2, None) , ( protein: interleukin-2, None) , ( protein: Syk, None) , ( DNA: interleukin-2 gene, None) , ( protein: ZAP-70, None) , ( protein: SHP1, None) , ( protein: SHP1 -DeltaSH2, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: mitogen-activated protein kinase, None) , ( protein: Erk2, None) , ( protein: interleukin-2, None) , ( protein: Syk, None) , ( DNA: interleukin-2 gene, None) , ( protein: ZAP-70, None) , ( protein: SHP1, None) , ( protein: SHP1 -DeltaSH2, None) 