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We observed 5 reactions in 3 patients that appear to be related to a high dose-infusion time ratio, indicating that dose and rate of infusion may be important factors in precipitating anaphylactoid reactions with cisplatin.
 ( adverse event: precipitating ,  3 patients: Subject, 3: Subject.Population, anaphylactoid reactions: Effect, high dose-infusion time ratio: Treatment, cisplatin: Treatment, high dose: Treatment.Dosage, cisplatin: Treatment.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: precipitating ,  3 patients: Subject, 3: Subject.Population, anaphylactoid reactions: Effect, high dose-infusion time ratio: Treatment, cisplatin: Treatment, high dose: Treatment.Dosage, cisplatin: Treatment.Drug) 