11549
The mutant, containing a serine -to- alanine substitution in the DNA-binding domain of the protein, bound to several known ZEBRA -binding sites and activated transcription from reporters bearing known ZEBRA -responsive promoters but did not disrupt latency in EBV -infected cell lines .
 ( protein: DNA-binding domain, None) , ( cell line: EBV -infected cell lines, None) , ( DNA: ZEBRA -responsive promoters, None) , ( protein: ZEBRA, None) , ( protein: ZEBRA, None) , ( DNA: ZEBRA -binding sites, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: DNA-binding domain, None) , ( cell line: EBV -infected cell lines, None) , ( DNA: ZEBRA -responsive promoters, None) , ( protein: ZEBRA, None) , ( protein: ZEBRA, None) , ( DNA: ZEBRA -binding sites, None) 