3914
Thus, IL-2 -induced IL-2R alpha promoter activity requires a complex upstream element , which appears to contain binding sites for both positive and negative regulatory factors .
 ( DNA: IL-2R alpha promoter, None) , ( DNA: binding sites, None) , ( protein: IL-2, None) , ( DNA: complex upstream element, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: IL-2R alpha promoter, None) , ( DNA: binding sites, None) , ( protein: IL-2, None) , ( DNA: complex upstream element, None) 