10247
Anti-Ehrlichia chaffeensis antibody complexed with E. chaffeensis induces potent proinflammatory cytokine mRNA expression in human monocytes through sustained reduction of IkappaB-alpha and activation of NF-kappaB .
 ( protein: IkappaB-alpha, None) , ( RNA: proinflammatory cytokine mRNA, None) , ( protein: NF-kappaB, None) , ( cell type: human monocytes, None) , ( protein: Anti-Ehrlichia chaffeensis antibody, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: IkappaB-alpha, None) , ( RNA: proinflammatory cytokine mRNA, None) , ( protein: NF-kappaB, None) , ( cell type: human monocytes, None) , ( protein: Anti-Ehrlichia chaffeensis antibody, None) 