4668
The ability to regulate AR gene transcription via the second messenger pathway is lost in the PC-3 and DU-145 cell lines .
 ( DNA: AR gene, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( DNA: AR gene, None) 