1848
T lymphocyte activation and interleukin-2 ( IL-2 ) production require at least two signals, generated by phorbol ester ( TPA ) and Ca2+ ionophore or costimulation of the T cell receptor ( TCR ) and the CD28 auxiliary receptor .
 ( protein: interleukin-2, None) , ( protein: TCR, None) , ( protein: CD28 auxiliary receptor, None) , ( protein: T cell receptor, None) , ( cell type: T lymphocyte, None) , ( protein: IL-2, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: interleukin-2, None) , ( protein: TCR, None) , ( protein: CD28 auxiliary receptor, None) , ( protein: T cell receptor, None) , ( cell type: T lymphocyte, None) , ( protein: IL-2, None) 