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Kinase C mediates its effects via phosphorylation of serum response factor ( SRF ) which interacts with the serum response element ( SRE ); cAMP and calcium mediate their effects via phosphorylation of CREB ( cAMP regulatory element binding protein ) presumably by activation of a protein kinase A or calmodulin-regulated kinase .
 ( protein: CREB, None) , ( protein: serum response factor, None) , ( protein: protein kinase A, None) , ( protein: SRF, None) , ( DNA: serum response element, None) , ( protein: calmodulin-regulated kinase, None) , ( protein: Kinase C, None) , ( protein: cAMP regulatory element binding protein, None) , ( DNA: SRE, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: CREB, None) , ( protein: serum response factor, None) , ( protein: protein kinase A, None) , ( protein: SRF, None) , ( DNA: serum response element, None) , ( protein: calmodulin-regulated kinase, None) , ( protein: Kinase C, None) , ( protein: cAMP regulatory element binding protein, None) , ( DNA: SRE, None) 