2365
CONCLUSIONS: In our reported case, a local hyperproduction of TNF-alpha from macrophages that was induced by the injected insulin could explain the dedifferentiation of the adipocytes of the subcutaneous tissue and the reversion that was induced by the local injection of dexamethasone.
 ( adverse event: induced ,  reported case: Subject, local hyperproduction of TNF-alpha from macrophages: Effect, dedifferentiation of the adipocytes of the subcutaneous tissue: Effect, injected insulin: Treatment, injected: Treatment.Route, insulin: Treatment.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: induced ,  reported case: Subject, local hyperproduction of TNF-alpha from macrophages: Effect, dedifferentiation of the adipocytes of the subcutaneous tissue: Effect, injected insulin: Treatment, injected: Treatment.Route, insulin: Treatment.Drug) 