6595
In response to activation of the Wnt signaling pathway , beta-catenin accumulates in the nucleus , where it cooperates with LEF/TCF (for lymphoid enhancer factor and T-cell factor ) transcription factors to activate gene expression .
 ( protein: lymphoid enhancer factor and T-cell factor, None) , ( protein: transcription factors, None) , ( protein: LEF/TCF, None) , ( protein: beta-catenin, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: lymphoid enhancer factor and T-cell factor, None) , ( protein: transcription factors, None) , ( protein: LEF/TCF, None) , ( protein: beta-catenin, None) 