2585
We report the case histories of two patients with histologically confirmed adenocarcinoma of the prostate, both of whom had been treated with steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation, and who subsequently developed femoral head avascular necrosis.
 ( adverse event: treated ,  two patients with histologically confirmed adenocarcinoma of the prostate: Subject, two: Subject.Population, femoral head avascular necrosis.: Effect, steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation: Treatment, adenocarcinoma of the prostate: Treatment.Disorder, cyproterone acetate: Treatment.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: treated ,  two patients with histologically confirmed adenocarcinoma of the prostate: Subject, two: Subject.Population, femoral head avascular necrosis.: Effect, steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation: Treatment, adenocarcinoma of the prostate: Treatment.Disorder, cyproterone acetate: Treatment.Drug) 