2336
Azole antifungals, prescribed prophylactically to avoid severe infections in immunosuppressed organ transplant recipients, can interact with drug substrates of CYP3A4.
 ( adverse event: interact ,  immunosuppressed organ transplant recipients: Subject, immunosuppressed organ transplant: Subject.Disorder, Azole antifungals: Treatment, drug substrates of CYP3A4: Treatment, severe infections: Treatment.Disorder, Azole antifungals: Treatment.Drug, drug substrates of CYP3A4: Treatment.Drug, drug substrates of CYP3A4: Combination.Drug, Azole antifungals: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: interact ,  immunosuppressed organ transplant recipients: Subject, immunosuppressed organ transplant: Subject.Disorder, Azole antifungals: Treatment, drug substrates of CYP3A4: Treatment, severe infections: Treatment.Disorder, Azole antifungals: Treatment.Drug, drug substrates of CYP3A4: Treatment.Drug, drug substrates of CYP3A4: Combination.Drug, Azole antifungals: Combination.Drug) 