4644
We report the effect of E3330 on transcriptional activation of tumor necrosis factor (TNF)-alpha gene and on nuclear factor (NF)-kappa B activation .
 ( protein: nuclear factor (NF)-kappa B, None) , ( DNA: tumor necrosis factor (TNF)-alpha gene, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: nuclear factor (NF)-kappa B, None) , ( DNA: tumor necrosis factor (TNF)-alpha gene, None) 