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A mutation of the MNP site which does not abrogate ICK-1 binding inactivates the GOS19.1 promoter in U937 cells and reduces its activity by fourfold in Jurkat cells .
 ( cell line: Jurkat cells, None) , ( DNA: MNP site, None) , ( cell line: U937 cells, None) , ( DNA: GOS19.1 promoter, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell line: Jurkat cells, None) , ( DNA: MNP site, None) , ( cell line: U937 cells, None) , ( DNA: GOS19.1 promoter, None) 