1297
A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease, developed clinical and biochemical features of severe cholestasis 3 months after initiation of azathioprine therapy.
 ( adverse event: developed ,  A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease: Subject, 67-year-old: Subject.Age, cholestasis: Effect, 3 months after initiation of azathioprine: Treatment, azathioprine: Treatment.Drug, 3 months: Treatment.Time_elapsed, primary polymyositis: Treatment.Disorder) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: developed ,  A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease: Subject, 67-year-old: Subject.Age, cholestasis: Effect, 3 months after initiation of azathioprine: Treatment, azathioprine: Treatment.Drug, 3 months: Treatment.Time_elapsed, primary polymyositis: Treatment.Disorder) 