14687
In summary, our data suggest that changes in the composition of transcription factor AP-1 is a key molecular mechanism for increasing IL-2 transcription and may underlie the phenomenon of costimulation by EC .
 ( cell type: EC, None) , ( protein: AP-1, None) , ( protein: transcription factor, None) , ( protein: IL-2, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: EC, None) , ( protein: AP-1, None) , ( protein: transcription factor, None) , ( protein: IL-2, None) 