6223
mRNA levels for IL-13R alpha1 , but not IL-4R alpha , were markedly decreased in in vitro monocyte-derived macrophages ( MDMac ), and with increasing time of monocytes in culture correlated with the loss of IL-13 regulation of lipopolysaccharide -induced TNF-alpha production .
 ( cell line: in vitro monocyte-derived macrophages, None) , ( protein: IL-13R alpha1, None) , ( protein: IL-13, None) , ( RNA: mRNA, None) , ( cell type: monocytes, None) , ( protein: TNF-alpha, None) , ( cell line: MDMac, None) , ( protein: IL-4R alpha, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell line: in vitro monocyte-derived macrophages, None) , ( protein: IL-13R alpha1, None) , ( protein: IL-13, None) , ( RNA: mRNA, None) , ( cell type: monocytes, None) , ( protein: TNF-alpha, None) , ( cell line: MDMac, None) , ( protein: IL-4R alpha, None) 