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Our findings reveal that monocyte-derived IL-1beta inhibits the proliferation of androgen-responsive prostate tumour cells and reduces AR and PSA levels .
 ( protein: AR, None) , ( protein: IL-1beta, None) , ( protein: monocyte-derived IL-1beta, None) , ( cell type: androgen-responsive prostate tumour cells, None) , ( protein: PSA, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: AR, None) , ( protein: IL-1beta, None) , ( protein: monocyte-derived IL-1beta, None) , ( cell type: androgen-responsive prostate tumour cells, None) , ( protein: PSA, None) 