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CASE REPORT: We report the case of a 58 year old patient who, after 2 days of treatment with roxithromycin and betamethasone, manifested acute pancreatitis.
 ( adverse event: manifested ,  a 58 year old patient: Subject, 58 year old: Subject.Age, acute pancreatitis: Effect, after 2 days of treatment with roxithromycin: Treatment, betamethasone: Treatment, roxithromycin: Treatment.Drug, betamethasone: Treatment.Drug, 2 days: Treatment.Time_elapsed, roxithromycin: Combination.Drug, betamethasone: Combination.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: manifested ,  a 58 year old patient: Subject, 58 year old: Subject.Age, acute pancreatitis: Effect, after 2 days of treatment with roxithromycin: Treatment, betamethasone: Treatment, roxithromycin: Treatment.Drug, betamethasone: Treatment.Drug, 2 days: Treatment.Time_elapsed, roxithromycin: Combination.Drug, betamethasone: Combination.Drug) 