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Whereas the Jak kinases Jak1 and Jak3 and the signal transducer and activator of transcription proteins Stat3 and Stat5 are activated in normal T cells in response to IL-2 , this signaling pathway was constitutively activated in HTLV-I -transformed cells .
 ( cell type: T cells, None) , ( protein: Stat5, None) , ( protein: Stat3, None) , ( protein: Jak3, None) , ( cell line: HTLV-I -transformed cells, None) , ( cell type: normal T cells, None) , ( protein: transcription proteins, None) , ( protein: Jak1, None) , ( protein: Jak kinases, None) , ( protein: IL-2, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: T cells, None) , ( protein: Stat5, None) , ( protein: Stat3, None) , ( protein: Jak3, None) , ( cell line: HTLV-I -transformed cells, None) , ( cell type: normal T cells, None) , ( protein: transcription proteins, None) , ( protein: Jak1, None) , ( protein: Jak kinases, None) , ( protein: IL-2, None) 