1394
The presence of a lymphocyte alveolitis with a predominance of CD4+ T cells in 3 RA patients and CD8+ T cells with a concomitant increase in neutrophils in another case suggests that immunologically mediated reactions may be one damage mechanism in MTX-induced pneumonitis.
 ( adverse event: induced ,  3 RA patients: Subject, 3: Subject.Population, a lymphocyte alveolitis with a predominance of CD4+ T cells: Effect, pneumonitis: Effect, CD8+ T cells with a concomitant increase in neutrophils: Effect, MTX: Treatment, RA: Treatment.Disorder, MTX: Treatment.Drug) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: adverse event,potential therapeutic event, Arguments type: Treatment.Disorder,Treatment.Time_elapsed,Treatment.Dosage,Subject.Race,Treatment.Drug,Treatment.Route,Subject.Disorder,Treatment.Freq,Treatment,Effect,Subject.Population,Treatment.Duration,Combination.Drug,Subject,Subject.Age,Subject.Gender. 
Text: {0} 
Answer:
 ( adverse event: induced ,  3 RA patients: Subject, 3: Subject.Population, a lymphocyte alveolitis with a predominance of CD4+ T cells: Effect, pneumonitis: Effect, CD8+ T cells with a concomitant increase in neutrophils: Effect, MTX: Treatment, RA: Treatment.Disorder, MTX: Treatment.Drug) 