7849
We propose that mutations of MDS1/EVI1 either by gene truncation resulting in the transcription repressor EVI1 or by gene fusion to AML1 lead to an altered cellular response to growth and differentiation factors that could result in leukemic transformation.
 ( protein: transcription repressor EVI1, None) , ( protein: differentiation factors, None) , ( protein: AML1, None) , ( protein: EVI1, None) , ( DNA: MDS1/EVI1, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: transcription repressor EVI1, None) , ( protein: differentiation factors, None) , ( protein: AML1, None) , ( protein: EVI1, None) , ( DNA: MDS1/EVI1, None) 