7417
The mutant alleles encode cell-surface IFNgamma receptors that lack the intra-cytoplasmic domain , which, through a combination of impaired recycling , abrogated signalling and normal binding to IFNgamma exert a dominant-negative effect .
 ( protein: intra-cytoplasmic domain, None) , ( protein: cell-surface IFNgamma receptors, None) , ( protein: IFNgamma, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: intra-cytoplasmic domain, None) , ( protein: cell-surface IFNgamma receptors, None) , ( protein: IFNgamma, None) 