5877
CD40 signaling activates downstream effectors , including the tyrosine protein kinase , Lyn , the phosphatidylinositol-3-kinase ( PI-3 kinase ), and the transcription factor, NF-kappa B .
 ( protein: phosphatidylinositol-3-kinase, None) , ( protein: PI-3 kinase, None) , ( protein: downstream effectors, None) , ( protein: Lyn, None) , ( protein: CD40, None) , ( protein: NF-kappa B, None) , ( protein: tyrosine protein kinase, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( protein: phosphatidylinositol-3-kinase, None) , ( protein: PI-3 kinase, None) , ( protein: downstream effectors, None) , ( protein: Lyn, None) , ( protein: CD40, None) , ( protein: NF-kappa B, None) , ( protein: tyrosine protein kinase, None) 