961
We show that IL-6 signaling leads to marked increases in the synthesis and secretion of Ig in clonal human B cell lines and newly isolated polyclonal B lymphocytes in vitro.
 ( cell type: isolated polyclonal B lymphocytes, None) , ( protein: Ig, None) , ( protein: IL-6, None) , ( cell line: clonal human B cell lines, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( cell type: isolated polyclonal B lymphocytes, None) , ( protein: Ig, None) , ( protein: IL-6, None) , ( cell line: clonal human B cell lines, None) 