10497
Five of these were caused by mutations predicted to produce a truncated protein : (i) a sporadic case showed a 32 bp deletion in exon 11 , and a mutant mRNA without exon 11 was produced; the normal exon 10 was also spliced out; (ii) a sporadic case had a 1 bp deletion in exon 12 ( 1634delT ); (iii) a TSC2 -linked mother and daughter pair had a G-->T transversion in exon 23 ( G2715T ) introducing a cryptic splice site causing a 29 bp truncation of mRNA from exon 23 ; (iv) a sporadic case showed a 2 bp deletion in exon 36 ; (v) a sporadic case showed a 1 bp insertion disrupting the donor splice site of exon 37 ( 5007+2insA ), resulting in the use of an upstream exonic cryptic splice site to cause a 29 bp truncation of mRNA from exon 37 .
 ( RNA: upstream exonic cryptic splice site, None) , ( RNA: 29 bp truncation, None) , ( RNA: exon 37, None) , ( DNA: 2 bp deletion, None) , ( RNA: mutant mRNA, None) , ( RNA: 5007+2insA, None) , ( DNA: 1 bp deletion, None) , ( RNA: mRNA, None) , ( RNA: exon 37, None) , ( RNA: exon 12, None) , ( DNA: 1 bp insertion, None) , ( RNA: exon 23, None) , ( DNA: 32 bp deletion, None) , ( DNA: TSC2, None) , ( RNA: TSC2 -linked mother and daughter pair, None) , ( RNA: G2715T, None) , ( RNA: exon 36, None) , ( protein: truncated protein, None) , ( RNA: exon 11, None) , ( RNA: exon 23, None) , ( RNA: exon 11, None) , ( RNA: 1634delT, None) 
Locate the role in the text that participated in the event based on the event type and return it in the event list. 
 Option: Event type: RNA,cell type,protein,cell line,DNA, Arguments type: . 
Text: {0} 
Answer:
 ( RNA: upstream exonic cryptic splice site, None) , ( RNA: 29 bp truncation, None) , ( RNA: exon 37, None) , ( DNA: 2 bp deletion, None) , ( RNA: mutant mRNA, None) , ( RNA: 5007+2insA, None) , ( DNA: 1 bp deletion, None) , ( RNA: mRNA, None) , ( RNA: exon 37, None) , ( RNA: exon 12, None) , ( DNA: 1 bp insertion, None) , ( RNA: exon 23, None) , ( DNA: 32 bp deletion, None) , ( DNA: TSC2, None) , ( RNA: TSC2 -linked mother and daughter pair, None) , ( RNA: G2715T, None) , ( RNA: exon 36, None) , ( protein: truncated protein, None) , ( RNA: exon 11, None) , ( RNA: exon 23, None) , ( RNA: exon 11, None) , ( RNA: 1634delT, None) 