in addition , nectar-13 had been shown to accelerate the aging process in the addict to an alarming rate , as well as cause unstable mood swings and an inability to metaphysically comprehend the existence of certain numerical quantities in base-10 ( including the number 13 , which , ironically , made it rather difficult for the chronic user to obtain more of the substance without first going through a rigorous detoxification regimen , orin dire circumstancesto even seek out a druggist well enough aware of the substances effects that he could make sense of the users pleadings for nectar-1101 by means of a simple binary-to-base-10 conversion ) .