Want to move fast?  Just do this
This is excellent, very practical advice.The one caveat I would add which the author glosses over is Test in IE as a high priority unless you have a very tech-savvy audience. Compass/Blueprint abstract away most of the uglier CSS box-model hacks and I agree that IE users can live without gradients and rounded corners. But if the site looks awkward without the CSS3 tricks that don't work on the browser that >60% of your audience uses, you're going to need to tweak that aspect as well .