Researchers looking for mRNA were ridiculed by colleagues
I was a student of Carl Woese, who studied mRNA in the 60s and 70s. He made the yuuge discovery of archaea being, not only the third domain, but closer related to humans than procaryotes. He wrote letters to Francis Crick too, which have been published.Another interesting person who was thought to be kooky was Douglas Engelbart https://hackaday.io/page/9869-the-mother-of-all-tech-demos-a...