Eating less and more than needed on alternate days prolongs life (2006)
I have long believed, due entirely to anecdotal evidence, that restricting calories and eating less is one of the best ways to add years to your life.  It seems that eating is inherently stressful for the body.  Though obviously necessary, eating is  something that we should strive to minimize.  Any more than necessary, and the stress induced from digestion, and inflammatory molecules, damages the body and undermines our ability to fight infection.