Hackathon Starter – Boilerplate for Node.js web application
If you want boilerplate, the Yeoman collection tools: http://yeoman.io/ is what you need. There's boilerplate for a huge amount of projects, with generators of the parts (like: service for Angular, models for Ember, routes for Backbone...).
The angular-generator is a very complex piece of work, but is extremely efficient. I highly suggest you to try it twice: once to fuck things up, another to understand the good way.You can eventually use these CSS and HTML skeletons (http://html5up.net/) to do something neat, but I don't think someone will judge you because you used bootstrap.In term of javascript development, I've found SugarJs (http://sugarjs.com) to be extremely productive and efficient for what I need, combined with the front-end framework of your choice.And you, what's yours ?