They're Made Out of Meat (1991)
This is a classic story and fun in its own way, but thinking about humanity future reach for the stars (provided it happens) will most likely require us to move to some trans human form. Think transformers or sentient ships. The human life is too short and body is too fragile for cosmic voyages. If we are going to be advanced enough to build interstellar ships, we should be advanced enough to travel in a different vessel.