Founder Depression
For founders, it is a good idea to scope which socio-economic-environmental factors would contribute to their dissonance or depression.  For me it's the lack of face-to-face contact, being an 'outlier' in so many respects, being in an environment that is not as innovative or open to entrepreneurs and so on.  The list is not that encouraging but as long as the factors are known at least they are 'known'.  Also these factors can easily contribute to freelancers, independent workers, etc.The next item to know is that there are factors that would actively contribute to depression.  I used to have some really bad habits that would otherwise feed into some sort of circle of depression and these would pop up when I am triggered.  These habits formed because of thought patterns that I have somewhat developed growing up.  Whenever I feel the triggers, I need to make sure that I don't engage in any of these bad habits or that if I do, I need to try and get out of that zone.I've had my first episode when I was really young - culminated in a few sessions with a psychologist at school - so I've had this affliction for a while now.  On top of that, I've been entrepreneurial since I was young so I think that the external 'being a founder' is hard to separate from the biology.It's a bit of a circle for me - I get in founder phases and then when the business or idea fizzles out or when I need the cash, I get into employee phase which then culminates in me wanting to get my feet back into the entrepreneur game... and so on and so forth.  At the moment I'm in that founder phase and have made commitments and arrangements so that I don't get back into being an employee for at least January 2015.