We tried to publish a replication of a Science paper in Science
The original paper was an n=46 study, and they have regression equations there with 5 coefficients. It has been known for a long time that you can't successfully adjust for confounding variables with such small data. The fact it didn't reproduce is easily predicted and hardly noteworthy. Everybody in the field is aware of this issue. This article is just a bunch of academics tooting their own horn. The Journal's response to their request was 'Who cares?', and this is the right answer.