The U.S. Department of Health and Human Services, Administration for Children and Families, Office of Family Assistance (OFA) Regions I through IV hosted the OFA Regions I-IV East Coast TANF Directors' Meeting, Leveraging Partnerships to Help Families Achieve Economic Stability, on July 24-26, 2018 at the Westin Boston Waterfront in Boston, Massachusetts. The meeting convened representatives from TANF programs from Regions I-IV and provided TANF representatives with an opportunity to learn about promising practices, discuss shared challenges faced by TANF programs, and share ideas with peers from other states about how to respond to the needs of low-income families. The meeting also included practitioners and researchers who shared information about their own work, and who looked to TANF representatives and federal partners for future research opportunities. Representatives attended presentations from experts and program administrators, and worked with other states to think of innovative practices during Team Work sessions.