- The presence of openings or fenestrae in a part. - Making openings in a dressing to allow inspection of the parts.- In dentistry, a surgical perforation of the mucoperiosteum and alveolar process to expose the root tip of a tooth to permit drainage of tissue exudate. - An operation to create an opening in the horizontal semicircular canal to improve hearing in otosclerosis. Search Stedman's Medical DictionaryExamples: glitazone, GI cocktail, etc.