Typically, four or more of the following eleven criteria must be present to make a diagnosis of Systemic Lupus. 1. Malar rash: butterfly-shaped rash across cheeks and nose2. Discoid (skin) rash: raised red patches3. Photosensitivity: skin rash as result of unusual reaction to sunlight4. Mouth or nose ulcers: usually painless5. Arthritis (non-erosive) in two or more joints, along with tenderness, swelling, or effusion. With non-erosive arthritis, the bones around joints don’t get destroyed. 6. Cardio-pulmonary involvement: inflammation of the lining around the heart (pericarditis) and/or lungs (pleuritis)7. Neurological disorder: seizures and/or psychosis8. Renal (kidney) disorder: excessive protein in the urine, or cellular casts in the urine9. Hematologic (blood) disorder: hemolytic anemia, low white blood cell count, or low platelet count10. Immunologic disorder: antibodies to double stranded DNA, antibodies to Sm, or antibodies to cardiolipin11. Antinuclear antibodies (ANA): a positive test in the absence of drugs known to induce it. Post Edited (Lynnwood) : 1/24/2018 11:02:18 AM (GMT-7)