The human body is exposed to a wide array of xenobiotics in one's lifetime, and complex enzymatic mechanisms are genetically available to detoxify these substances. A variety of mechanisms support, or impair the body's natural ability to detoxify and scientific literature suggests an association between impaired detoxification and certain diseases. Missing or nonfunctioning enzyme systems impair biotransformation systems, consequently increasing the need for lifestyle changes, including the avoidance of certain toxins. It avoid or reduce the effects of a toxic metal overload, the body's natural detoxification mechanisms can be supported, and chelation therapy is one option. Material needed for genetic testing:1ml whole blood in EDTA tubes or 10 drops of whole blood on filter paper, or a gum swap. Ask for test kits or download submission form and send with appropriate sample.