###Human: Does numerous enlarged lymph nodes with Epstein Barr virus indicate lymphoma? ###Assistant: Hello. Hereby, I am giving my opinion for your case. You are having ebstein bar virus infection. This virus can lead to hepatitis development and enlarged lymph nodes. You are right on your suspicion that multiple enlarged lymph nodes raised suspicion towards malignancy especially lymphoma. But the main thing is biopsy is considered conclusive and your flow cytometry report is clearly suggestive of non-malignant lesion that is polyclonal cells are present. So these reports are not suggestive of any lymphoma. You have mentioned diagnosis as primary biliary cholangitis, so in this autoimmune disease, liver enzymes can be elevated. In this disease, over the time cirrhosis also can be developed. No need of repeat biopsy just now as per the mentioned report. Consult a gastroenterologist for primary biliary hepatitis. Take care.