###Human: Maintenance drugs in kidney carcinoma patient has been stopped. What is your opinion? ###Assistant: Hello. I have gone through the details about your history. Cause of deranged renal function is multifactorial. First of all, Ketruda that is Pembrulizumab can cause interstitial nephritis, that can cause damage to kidney and rise of creatinine. Sartel is for blood pressurebut it can cause rise in creatinine in acute setting such as after surgical stress, so stopping is a good decision. When there is a damage to kidney, drug such as Gabapentin get accumulated in body and can cause neurological symptoms as you told. It will subside gradually as kidney function improves. So, from current medicines, you stop Parozep until his kidney recover, for blood pressure take Amlodipine 5 mg (as the blood pressure is normal now) (attachment removed to protect patient identity). Get urine routine done and urine protein creatinine ratio and if creatinine continue to rise, a kidney biopsy may be needed. Otherwise, control of potassium and urine output as per regular protocol of treating nephrologist. Take care and would like to know further detail and progress, wishing him a speedy recovery.