###Human: What can cause on and off tingling in arms and legs? ###Assistant: Hi. I have read your complaints and first of all I should compliment you for having patiently written a thorough history of events. Let us analyze your problems You have tingling in all four limbs and weakness in all four limbs. That is upper limbs and lower limbs on both sides, but onset on various days. The next important point which you have told is the mode of onset and the tingling eventually subsided. The following parameters can be found out only by a clinical examination and they are most important to fix the diagnosis. In the same way, need to get at least two investigations, nerve conduction studies and MRI spine. It can be either a peripheral vascular disease leading to low perfusion or a peripheral neuropathy. I would strongly recommend as well as request you to consult your neurologist immediately and treat these symptoms as top priority. 1. Nerve conduction studies. 2. MRI spine. The symptoms suggest either it could be peripheral neuropathy or peripheral vascular disease. Revert back with the investigation report to a neurologist online.--->