###Human: What are the symptoms of frontotemporal dementia? ###Assistant: Hi. I read carefully your question and would explain that fronto-temporal diagnosis is a very challenging diagnosis, which is determined by the neuro-psychological tests and the progression of the disease. Sometimes, the radiological findings are not typical of this disorder, so I am not very surprised to learn that her MRI findings are not compatible with the diagnosis. Did she perform any MRI four years back? Some changes between the two MRI would help determine the diagnosis. Does she have memory problems or speech problems? Anyway, you should know that sometimes the first signs in frontotemporal dementia are just depression or psychosis. Memory problems or speech problems come next (in the next years). So, if there is a progression of the disease, the diagnosis of FTD would be more probable. Does she have any family history for dementia? If her symptoms are completely reversible from antidepressants or antipsychotic therapy, the diagnosis of FTD would not stand. So, there is not too much to be done, besides treat her symptoms and wait to see for possible further progression. Genetic test for FTD can be done too.