###Human: I have fever and leg pain from yesterday with a history of preauricular sinus. Please help. ###Assistant: Hello. I have gone through your query. As per your query, you have taken multiple antibiotics for a long time which is not good. I need to know whether you have done a culture sensitivity test for the pus draining out of the sinus or not, because if you take antibiotics according to the culture then chances of recurrent sinus infection and fever are very less. Can you send me the photos of your infected area (preauricular sinus)? Mostly pus discharging sinuses are caused by tuberculosis infection in most of the cases. In my opinion, you should go for a detailed physical and systemic examination along with some blood tests and chest x-ray. Also, if discharging sinuses is still persisting then you need to do a pus culture sensitivity test both for bacterial culture and Acid fast bacilli (AFB) culture and other advanced tests for tuberculosis. Now you can take tablet Paracetamol 650 mg whenever you develop a fever. Please do not ignore your problem as it can lead to deterioration of your health. I suggest you to consult a physician and get a detailed physical and systemic examination done and detailed evaluation along with the above tests.