###Human: Can anal fissure cause itching and infected skin between anus and genital area? ###Assistant: Hello. You seem to have a fungal infection. I suggest you take Itraconazole 100 mg capsule (Ceastra XL 100 mg), twice daily for two weeks. In addition, I suggest you apply either Loceryl cream or Fungicros cream, twice daily for four weeks. You may also take an oral antihistamine like Cetirizine 10 mg tablet once a day for symptomatic relief from itching. Take care.