###Human: ALT and AST are out of range. What does it mean? ###Assistant: Hi. Based on your query, my opinion is as follows: Alcohol induced liver damage has caused increased enzyme levels. Possibly early stages, as no jaundice is seen. MCV high (mean corpuscular volume) is due to associated vitamin B12 and folic acid deficiency. Malnutrition due to alcohol abuse has caused this. Need to abstain from alcohol on an immediate basis as liver would take another six months to possibly recover. Repeat the test after three months. Also start Vitamin B12 and Folic acid supplements. Nothing major for now. If it progresses then may require liver transplant in next few years. For further information consult a hematologist online -->