###Human: How will herpes labialis spread? ###Assistant: Hi. As I understand you are conscious about you and your friend's health. But, no need to worry. First, I would like to tell you that herpes infection are transmitted by direct contact like kissing and manifest with multiple painful vesicle, which may develop to ulceration associated with pharyngitis or ulcer over oral mucosa. So, if you had a kiss by a confirm case of Herpes labialis, you may get such infection. But, it is not always an infection to convert into a disease as body's immune system protects us from such kind of pathogen. I do not think to go for viral culture as it will not help in deciding treatment plan. Viral infection usually gets cured itself within 10 to 14 days. We need to do symptomatic treatment and maintain good nutrition and hydration. You may be having a herpes infection, but do not worry. For further information consult a microbiologist online -->