###Human: Is it necessary to get a second round of antibiotic course for sinusitis? ###Assistant: Hello. You do not need to go back to the doctor for antibiotics. If you were to come to me at this point, I will examine you and make sure the disease process has reduced. And if everything goes well, I will prescribe you some mucus lightening agents with anti-allergic and continue the spray. Mucus lightening agents are Ambroxol or N-acetylcysteine. Ambroxol 30 mg can be taken twice daily for 3 to 4 days or you may take 75 mg (Ambroxol sustained release) once daily for 3 to 4 days and thereafter continue either of these regimens till you have phlegm. Anti-allergic is Deslor (Desloratadine 5 mg) taken once daily or Levocetirizine 5 or Cetirizine 10. Add Singulair 10 mg once daily with these. These two you may have to take till winters resolve. Continue Flonase spray as prescribed. Can try some nasal douching once or twice daily to help alleviate the symptoms. Saline douching can be done. Nasowash is a premixed sachet with saline powder which you gotta mix in water and douche the nose.