###Human: Will medications for Gout interfere with values of liver function test? ###Assistant: Hi. I have seen your blood works. (attachment removed to protect patient identity). It is all normal. Usually, during the acute attack of gout, we do not start Allopurinol or uric acid decreasing medications as it can exaggerate the situation. We usually start after the acute situation is treated with drugs like NSAIDs (non-steroidal anti-inflammatory drugs). Allopurinol is started with caution if there is liver disease, kidney disease, diabetes, congestive heart failure, and high blood pressure. Are you pregnant or breastfeeding? Are you receiving chemotherapy drugs? Allopurinol can decrease the number of blood cells in your body that causes blood clot and that help you fight infections, which can make it easier for you to bleed from an injury or get sick when exposed to others who are ill. It can increase liver enzymes to decrease the blood elements. But I have seen your blood works and it is fine. If someone has kidney stones due to increased uric acid, or recurrent gout episodes, or uric acid deposition on soft tissues that is the time usually Allopurinol is started and continued I think you do not have these problems. You need to decrease your protein intake like less meats, fish, lentils, eggs, and avoid diuretics which are used to treat high blood pressure. Alcohol intake to be reduced as well. You told your HBA1c (glycated hemoglobin) is 5.7 that is pre-diabetes or borderline diabetes, so better check your fasting sugar and sugar after two hours of eating. You need to do exercise even if it is just walking for one hour daily. Stop or reduce carbohydrates especially sugar in tea and sugary juices, bread, rice, pasta, and potatoes. Intermittent fasting can also help in decreasing weight and controlling sugar. Lifestyle modifications can help a lot in your case. Have you done any ultrasound abdomen?