###Human: I noticed a new mole in my toe. Is that cancer? ###Assistant: Hi. I went through your case history and the photos provided by you (attachment removed to protect patient identity). I can see a dark irregular lesion of about 5 mm in size over the tip of the toe. As it is to 3 days history the first thing I want to rule out is an history of injury or bruise.They do present like this and you may have forgotten the history of trauma. Secondly, moles also appear at this age and they also present like this if you have tendency of moles this may be a normal mole you can just observe it for few days. The other thing obviously is melanoma, acral lentiginous melanosis, this can be dangerous and has to be ruled by biopsy as soon as possible. But as you do not have any family history and if you do not have any other or very few moles over other parts of the body the chances again become very less. And again such a small history of the lesion the possibility is least. But to be sure you should monitor the lesion. Observe it for 5 days. If due to trauma, it will diminish and slowly go away. If persist and grow more immediately, go for a biopsy by a dermatologist for histopathogical examination. trauma, biopsy after 5 days. Intradermal hemorrhage, nevus nevus excision. none after 5 days.