###Human: What has to be done for stage 2 glioblastoma? ###Assistant: Hello. According to the MRI report, it looks like high-grade glioma and more likely glioblastoma. Just to correct you, glioblastoma is a grade 4 (highest grade) tumor and it is synonymous with brain cancer. But it needs to be operated. Then only we will get a definite diagnosis and after debulking the tumor, he can undergo radiotherapy and chemotherapy if it is a glioblastoma only. Overall prognosis is bad if it is glioblastoma. Surgery with chemo or radiotherapy will only prolong survival by a few months but definite diagnosis can only be done after surgery and biopsy of the tumor.