###Human: How can I overcome pruritus ani? Please help. ###Assistant: Hi.I can understand your concerns as I have analyzed each detail that you have provided. I have managed lots of cases with matching condition and feel that you too will make good use of the information and suggestions. I am sure the problem can be managed even though it might not be possible to do so in a matter of days. The key to treatment is to let the skin heal, remove any cause of irritation, and break the cycle of itch-scratch which is bound to have resulted in thickening of the affected skin.