###Human: What are the significant symptoms and causes of depression? ###Assistant: Hi. Hearing a strange voice is a symptom of psychosis which can be a symptom of depression. Low mood, lack of interest in previously pleasurable activities and lethargy are some significant symptoms of depression. Genetic cause, a reaction in an unhealthy way to a life stressor, hormonal changes especially in females are some causes of depression. Recovery from depression varies with client symptoms. High mood and confusion can be a symptom leading to seeing of images. Consulting a doctor is essential.