###Human: My HSV 1 IgG value is 49. 20. Why is it so high? ###Assistant: Hello. HSV (herpes simplex virus) IgG (immunoglobulin G) antibodies indicate previous exposure and HSV IgM (immunoglobulin M) indicates current disease. The positive IgG can become significant only if you have active lesions. The type one usually causes oral lesions which look like small blisters. The HIV testing recommended post exposure is the PCR (polymerase chain reaction) or the fourth generation. Which testing did you get? If the antibodies are negative for three months out it is a good sign. But I would be satisfied if HIV by PCR is obtained. I hope I have answered your questions.