###Human: What is the reason for three recurrent miscarriages? ###Assistant: Hello. The presence of ANA positivity (attachment removed to protect patient identity) indicates that you have thrombophilias and this could be acquired or inherited and hence you would have to get a complete thrombophilia screening done, like ACLA, APLA, LAC, protein C, and S deficiency, antithrombin 3 deficiency, factor 5 Leiden mutation, serum homocysteine levels. Pregnancy is possible but once heart rate arrives, then you would have to be on LMWH (low molecular weight Heparin) or Enoxaparin injections daily till your delivery to sustain and maintain pregnancy. You can discuss further if in doubt.