###Human: Please suggest the dose of Anafranil for OCD. ###Assistant: Hello. Anafranil (Clomipramine) is a type of older antidepressants, and it has some undesirable side effects like constipation dryness of mouth, at times effect on the heart. Because of the side effect for file usually, doctors refrain from going for higher doses. But if you are not facing any adverse impact, then we can increase the dose of drug top to 150 to 200 mg. The toxicity of this drug occurs easily as compared to SSRI (selective serotonin reuptake inhibitor) which is again a limiting factor for prescribing commonly. But always follow your treating doctors advice in increasing and decreasing the doses of drugs.