###Human: Why does urine appear dark brown inspite of having Fluconazole? ###Assistant: Hello. Went through your post. Generally, urine culture growth showing candida is not anything significant because it is a benign infection and usually does not need treatment unless a person has taken a lot of antibiotics, or is HIV positive. The white substance in urine is phosphate, and it is called Phosphaturia you are taking plenty of water is helpful, so no need to worry about that. I would suggest you complete two weeks of Fluconazole but no other antibiotics.