###Human: I am suffering with premenstrual syndrome. Please help. ###Assistant: Hi. I went through your query and I can understand your condition. First of all, I need to know whether your hypothyroidism is under control or not. Kindly upload your recent TSH (thyroid stimulating hormone) report. Now we need to see whether your headache and irritability is due to your PMS (premenstrual syndrome) or if there are some other reasons. Your endocrinologist will evaluate for that. But a simple way to know is to halt your periods for two months and observe what happens. Ask your general practitioner to prescribe you certain oral contraceptive pills. This shall halt your periods for a month or two and if you feel better then it is due to PMS. But if there is no improvement then other evaluations have to be done including your blood pressure testing, eye check up and if necessary brain scan. If there is an improvement then you can take the contraceptive pills for three to four months and then stop and observe.