###Human: Can bone metastasis disappear after chemo treatment? ###Assistant: Hi. I saw your Positron Emission Tomography PET scan report (attachment removed to protect patient identity). If I was your oncologist, I would be very satisfied with the report. Bone metastasis cannot completely disappear after treatment. They become less prominent. As I have mentioned, it is a very satisfying result for the treating doctor. Regarding reaction to Femara (Letrozole), normally it is very safe drug, but reactions can occur in rare cases. Tamoxifen (Nolvadex) is also a very effective drug. Your oncologist might try again Femara after one to two years or even earlier. I think your treatment is on right track. Follow the instructions of your oncologist. All the best. For further information consult a medical oncologist online -->