###Human: Can you list the drugs incompatible with Quetiapine and Lamotrigine? ###Assistant: Hello. As such for Lamotrigine following drug interactions need to be considered as important. For Quetiapine, Cytochrome P450 (CYP450) enzyme inhibitors reduces clearance of Quetiapine hence raises Quetiapine levels, therefore dosage needs to be reduced. May increase effect of antihypertensive agents. Besides these interactions no other major interactions with any other group of drugs.