###Human: After analysis of pleural effusion fluid, diagnosed with Stage 4 Cancer. ###Assistant: Hi. Thanks for the information given. To get the facts right, patient is a 74 year old female with prior history of Anal canal cancer and Breast cancer (DCIS) treated with surgery and radiation. Her co-morbidity includes osteoporosis / prior UTI / Lung fibrosis / multiple fractures ? metastatic disease ? weak bones. Is it possible to do a PET/CT scan which can give a clear idea on the extent of the disease? Your doctor would be able to give much more clear idea on it based on the need and present health status permitting it. Based on your information, I feel that it is currently a stage 4 disease with pleural effusion. If fluid is too much, she may require a drain to keep her breathing comfortable. After a complete drain, she may undergo pleurodesis to prevent re-collection again. This will help her definitely. But the doctor should decide based on her present health condition. Regarding further treatment (chemotherapy/targeted therapy), it may not be possible for me to comment without physically seeing/examining the patient. Your doctor may guide you better after discussions. She would need pain killers either oral or as replaceable patch based on the intensity of pain and requirement of pain relief. But at one point of time, I am afraid to say that all treatment have to be stopped just to continue hospice care and this is unavoidable. Hope I have answered your queries. I would be available to answer more of your questions, if any. Take care.