###Human: Even after surgery and chemo, some swelling in neck was detected as SCC. Is it possible? ###Assistant: Hello. I am sorry to know the recurrence of cancer. (attachment removed to protect patient identity).  You got diagnosed with squamous cell carcinoma in buccal mucosa of the left oral cavity in December 2019 which was operated. Then you received chemotherapy and radiation therapy and now on routine evaluation, there are some new lesions coming up in the thyroid and neck. So basically there are two sites of new lesions now, in parotid and around it one more lymph node. So please undergo a biopsy of this lesion from parotid to see if it is same cancer as before or a new second primary cancer. If it is confirmed as same cancer as before, it will be operated and taken out and also few more lymph nodes on the same side of the neck followed by chemotherapy. If a second primary cancer, then treatment can be different depending upon what type of cancer it is (on biopsy). So your first step is biopsy.