###Human: Can hemoglobin A2 level 4. 3 indicate a carrier of beta-thalassemia? ###Assistant: Hi. Your attached CBC report shows normal hemoglobin and MCV with RBC count is also within range (attachment removed to protect patient identity). I have calculated Mentzer index as well which is also not in favor of thalassemia minor. Moreover, in the report, also it has been mentioned that referral to higher laboratory needed for confirmation. So, your chance of having thalassemia minor is less. I suggest you investigate with Hb electrophoresis by HPLC method to exclusively rule out thalassemia minor in a different laboratory.