###Human: Is Bimatoprost safe enough for optical nerve damage? ###Assistant: Hello. I understand your concerns, and I am very sorry to hear about your mother's eye changes. I am afraid that the changes in the optic nerve are indeed irreversible and according to the reports is near total. This is known by the part of the reports that say CDR 0.9 in both eyes. To explain it in a very simple manner, the eye is like a camera, both have lenses, and just like the camera has a film, the eye has the retina. If there is a problem in both the lens and the film, simply changing the lens would not improve the quality of the picture as the film (retina) is also compromised. But in few cases may improve to a limited, yet unknown extent. The problem also gets compounded with her poor general condition with heart problems along with the recent sepsis. So operating on her cataract is quite risky. Regarding the eye drops, Brimonidine eye drops have been known to help in neuroprotection and may help in the preservation of whatever optic nerve function is left, theoretically. So this would be the thought process behind this plan of management given to the overall condition. As far as the next step in managing, it depends on the daily activities of your mother and if at all she feels her current vision is not enough for her to carry out the daily routine activities. In case you need more information, please let me know.