###Human: Having kell antigens in blood during pregnancy cause any permanent effect in babies? ###Assistant: Hi. Kell blood group is a minor blood group system. ABO and Rh are called major blood group system. Kell antigen can be antigenic and can create a problem during a blood transfusion or else it may not create any problem. So there is no need for having a specific treatment. Whenever your child requires a blood transfusion, the blood bank should find the right blood suitable for your child as per cross match report. Please mention the blood group of your partner and first child. If the mother is Rh negative and the child is Rh positive, then there is a chance to have a hemolytic disease of a newborn, and it requires anti D.