###Human: Can I combine 7. 5 mg of regular Paxil with Paxil CR for about a week or month? ###Assistant: Hi. It is safe to take the additional 7.5 mg of Paxil or Brisdelle along with 37.5 mg of Paxil CR, as you rightly mentioned that both are same medicines. The increase dose of Paxil or Brisdelle for short time is for managing your hot flashes, and it is just like that the dose of Paxil are increased to manage your symptoms. If your symptoms are well managed by this then it is good otherwise you may need to increase the dose further. The CR and regular difference is just how the active ingredient of the pill is released in body and to minimize the side effects of sudden increase of drug in body.