###Human: Is Progynova advisable to build up endometrium in a primary infertility patient? ###Assistant: Hello. As you are on day 8, ET (endometrial thickness) is low for the day of the cycle. You should be starting on Progynova (Estradiol) 2 mg one tablet twice a day for the next seven days. Your follicular scan days should be on day 11, 15 and 17. The follicles are appropriate for the age in the right ovary and are developing. The left ovary may be a simple cyst or late recruited follicle from the previous cycle but needs to follow-up with scan. At a follicular size of 20 mm, you should be opting for injection hCG 10000 IU intramuscularly for initiating ovulation. If this is a timed intercourse cycle and not an IUI cycle, then intercourse should be started daily from the day of hCG injection, else IUI to be done after 36 hours of injection hCG administration after a TVS scan (transvaginal ultrasound) to confirm rupture of follicle and also endometrial thickness (target 8 to 9 mm). Also progesterone-like tablet Susten (Natural Micronised Progesterone) 2000 mg one tablet twice a day can be started from day 16 for the next 10 days, to support pregnancy if fertilization occurs. On day 14 post ovulation, you may get a serum beta hCG test done to check for conclusive results with regards to pregnancy.