###Human: How is the best Insulin treatment selected for a diabetes patient? ###Assistant: Hi. Rather than the best way, we consider more convenient and economical ways for the patient. The best is always an Insulin pump, but it is costly and requires continued patient education. Injecting Insulin into the same site will cause damage to the fat tissue which results in necrosis (cell death). Because of the fat damage, hard bump forms. New inhalation Insulin is not yet come into usage in full fledges. Also, I have not put any of my patients yet on inhaled Insulin, so cannot comment. But yes, initially it has to be supplemented with subcutaneous Insulin as dosing and efficacy is not completely established for Inhaled Insulin. Islet cell transplant is recommended for patients of type 1 diabetes who are difficult to control on Insulin (by any method). If the transplant is considered for only diabetes purpose then only islet cell transplant is sufficient. The pancreas has other functions like digestion. If the digestion system gets impaired in a patient who is requiring islet cell transplant, in such a patient'sentire pancreas transplant would be helpful. Well, if no immunosuppressant is used post-transplant, these autoantibodies can destroy the newly transplanted pancreas also.