###Human: What does increased IgE and immunodeficiency states in report indicate? ###Assistant: Hello. You have not mentioned that reason for which you got this test done. Anyways most of the doctors send for this investigation considering allergy (to dust particles) in the blood. Hence, the test was done and the report suggested mild elevation of serum IgE which indicates you have a little affinity for dust allergy but this is not a very significant rise hence take precautions by avoiding dust, regular usage of masks or handkerchiefs, keeping your pillow covers and bed sheets clean. Allergy. Vitamin D levels.