###Human: Kindly suggest the best medicine for depression, anxiety, and lack of confidence. ###Assistant: Hi. I understand you are suffering a lot due to your depression and anxiety. Most medications given for depression as well as anxiety have similar efficacy. As per the history given by you, I think you have benefited from treatment suggested by the last doctor. I would advise you to continue tablet Nexito 10 mg in the morning and tablet Mirtaz at night around two hours before sleep. You can withhold tablet Clonazepam if you feel too sleepy. Along with medicines, I would advise you to focus on your diet and sleep hygiene. You can choose a physical activity and continue it. It will help you. There are some relaxation exercises like Jacobson's muscular relaxation techniques. These will help reduce the physical symptoms of your anxiety. Please follow up regularly with your doctor and continue medicines started for atleast six months.