###Human: Is Mitomycin C necessary for urinary bladder cancer? ###Assistant: Hi. Superficial bladder cancer or nonmuscle invasive bladder cancer includes carcinoma in situ (CIS or Tis), Ta tumors, and T1 tumors. These are all cancers that have been found very early in their development. The cancer cells are only in the lining of the innermost layer of the bladder. These type of tumors have more than five-year survival rate, but the recurrence is an issue. Multiple trials have shown intravesical instillation of BCG (Bacillus Calmette-Guerin) or Mitomycin C (MMC). This has shown progression in 7.67% of the BCG subjects and 9.44% of MMC subjects. I would suggest you go for it. I have seen patients surviving for two decades after such therapy.