###Human: The stretch marks on my inner thighs hurt. Please help. ###Assistant: Hi.I have gone through your history and picture (attachment removed to protect patient identity). I get your worry. I can see that you have already tried a lot of therapies for the same with not much relief. Weight gain is usually a gradual process and not much skin stretch pain is experienced. But few nerve endings become exposed to the exterior in the stretched skin. When weight loss occurs, stretched skin hangs back loose. But it is still not back to normal skin. It is still thin and exposing your sensitive nerves when you stretch, like when you sit or squat. This is why you get that pain sensation during such activity.Now having considered that you have tried most of the options, I would suggest you try a few additional measures that can help.