###Human: My girlfriend takes Microgynon for PMS. Is it normal for her to experinece spotting? ###Assistant: Hello. Your doctor is right in saying that this is normal with the medicine you are taking. Microgynon is progesterone. It is a hormone which builds up and helps in the growth of the inner layer or lining of the uterus called endometrium. Due to overgrowth sometimes the endometrium sheds off and appears as vaginal bleeding or periods. The drug is otherwise safe just that continuous bleeding is a nuisance and may lead to anemia. She must take some iron supplements and wear a panty liner. For PMS (premenstrual syndrome), she can try a few things after the course of medicine is finished. She must stop taking tea and coffee. Minimize her salt intake and less water for a week before her expected periods. Also, PMS is a broad term, and treatment depends on what symptoms bother her more.