###Human: I have single lymph node enlargement. Is this due to cancer? ###Assistant: Hi. Based on your queries, my opinion is as follows: Node is partially fibrotic, so it is not able to go back to its original size. There is no reason for it to grow, as there is no infection or cancer. Yes, nodes are persistent and usually multiple and increasing in size. But here it is not. At your age, very low chance for cancer. If doubtful, get an FNAC or biopsy of lymph node done. It will confirm. Blood work is useless, unless it is blood cancer. Do get back with the biopsy of the lymph node and stool examination report for further opinion. At present, no cancer based on clinical details. 1. Lymph node biopsy. 2. Ultrasound abdomen. 3. Stool examination.