###Human: Why is there pain in hands and feet with fever? ###Assistant: Hi. From the description, it seems your son is having an upper respiratory infection. If he is playful and active in between fever it may be a simple infection which will subside by its own. You can give Paracetamol during the fever spikes. If his fever is lasting for more than three days, then you have to do a blood test including complete blood counts and may go for antibiotics after consulting a doctor in person. Pain can be part of the infection.