###Human: What causes pressure in the body with headache while standing? ###Assistant: Hello. I passed carefully through your question and would explain that your symptoms could be related to orthostatic hypotension or thyroid gland dysfunction. Anxiety can mimic this clinical situation too. Coming to this point, I would recommend performing some tests: 1. Complete blood count for anemia. 2. Thyroid hormone levels for possible thyroid gland dysfunction. 3. Blood electrolytes for possible imbalances. 4. Vitamin B12 and vitamin D plasma levels for a possible deficiency. A head-up tilt test would help investigate for possible orthostatic hypotension. You should discuss with your doctor on the above tests. If all the above tests result normal you should consider anxiety as the main cause underlying your complaints.