###Human: My sister has pain in the legs from thigh to knee. Please help. ###Assistant: Hello. Went through your queries and the files attached (attachment removed to protect patient identity). This clinical scenario is possible in two cases. 1) Compression of the spinal cord at the cervical level or lumbar level or both. 2) Peripheral neuropathy is affecting all four limbs. She has been extensively investigated. Treatment for peripheral neuropathy has been tried in the form of pregabalin, gabapentin, nor tryptiline, etc. which do not seem to have afforded any improvement to her. So I suggest we may try a course of the following medications for a week. Kindly consult your doctor to discuss the suggestion and take the treatment with consent. 1) Tablet Medrol 4 mg 1-0-1 after food (Methylprednisolone). 2) Tablet Pan 40 1-0-1 before food (Pantoprazole). 3). Tablet Phlogam 1-1-1 before food (Trypsin, Bromelain, Rutoside). 4). Tablet Nurokind LC 1-0-1 after food (Vitamin B12, Levocarnitine). 5). Tablet Nervijen-NP 1-0-1 after food (Nortryptiline, Pregabalin). 6). Tablet Alsody 1-0-1 after food (Alpha lipoic acid, Superoxide dismutase). Cervical stenosis, lumbar stenosis or peripheral neuropathy.