###Human: What is the role of calcium in blocking blood vessels?Is it reversible? ###Assistant: Hi. I assure you not to worry as everything is going to be fine if proper care and treatment is opted in for. I have thoroughly gone through your case and can well understand your genuine health concerns. Cardiac calcification if not yet gone to the level of irreversible stage, can be reversed. But I want to add that we may prevent but not reverse the advanced calcification.  Lot of researches available on this topic, some in favor and some against this school of thought. Dr. Dean in her Book The Magnesium Miracle says "Crush a calcium pill and dissolve it in 1 oz of water, some portion will left over undissolved. Now take Magnesium pill, crush and slowly stir it in that water. Miraculously, undissolved calcium will start dissolve. Same happens inside human body".  Calcium and magnesium are important parts of the body and coronary vessels also have the same salts in it. Calcium if accumulated, Magnesium salts are used for dissolution of the calcium. Same is true with kidney calcium stones.  Muscle spasms, hardened vessels in cardiovascular system and even weaker bones and dental cavities can occur if you have less magnesium in the body. Magnesium pushes the calcium in bones and teeth and blood is cleared of the toxic effects of the calcium excess. Bone mineral density is actually under the control of magnesium, not calcium.  Very authentic studies have shown all the benefits of the magnesium usage for calcification reduction.  The level of your calcification and the triple vessel disease which you have all made the three cardiologists more justified to say it is irreversible. But let me add that it will stop it here (if not genetic predominant) and further calcification will be lowered. Yes, crystallized Magnesium chloride is beneficial. But should not mix it with other forms of Magnesium. This is a good salt and take it alone if prescribed. But you are already taking a good form and that is Glycinate.  Yes, EDTA (chelation) supplements are effective to some extent. They actually bind to the extra salts including calcium and chelates them and saves body from side effects and toxicities of overload (orally one capsule a day).  No they do not block Gamma-linolenic acid (GLA). There is not much research done and a little data available on this issue. But I usually say that whatever Aspirin/Plavix do to the GLA, they are inevitable and the benefits overweigh the risks. I need some answers, to assist you better.  1. Have you been prescribed Magnesium Chloride (crystallized) and EDTA supplements?  2. Which joints are mainly involved in osteoporosis?  3. What is your lipid profile levels?  4. Are you diabetic and taking medications? But I cannot see about it in the history.  5. How much remains your blood pressure?  6. Do you take some dietary fiber supplement?  7. How much water do you take daily?  In a follow up query, please do answer these. Revert back with answers to the above questions to a cardiologist online.--->