###Human: Can high protein levels indicate cancer in ANA patient? ###Assistant: Hello. The elevated high total protein does not indicate malignancy only. It could be due to some temporary infective etiology as well. Your all other parameters do not indicate any blood cancer. If you have a history of positive beta 2 glycoproteins as mentioned in the above description then you have to repeat your beta 2 glycoprotein estimation again after 12 weeks. If two repeated tests for beta 2 glycoprotein are positive and any history of thrombosis, then anti-phospholipid lipid syndrome can be possible or else not. The positive Smith antigen points towards lupus. If asymptomatic, then no need for treatment and only monitoring can be done. However, you can repeat your Smith antibody estimation again to exclude the possibility of lupus. You can investigate with anti-ds DNA estimation as well to exclude SLE. If beta 2 glycoprotein result comes negative in the repeat test, then no need to take Aspirin. The occasional Aspirin ingestion has no value and not indicated. You can consult nearby hematologist for detailed evaluation.