###Human: Kindly explain about the diastolic heart failure. ###Assistant: Hello. I am sorry to hear that you did not receive any detailed explanation of your condition. Diastolic dysfunction is the inability of the heart to relax, which can be diagnosed with echocardiogram or with evidence of high pressures inside your heart chambers, as evidenced by the increase LVEDP (Left ventricular end-diastolic pressure) in your cardiac cath (it was 24 mmHg, and normal is considered less than 15 or 18 mmHg). The term diastolic heart failure is used when we have evidence of diastolic dysfunction as above in addition to symptoms of heart failure (the shortness of breath you described). There is some belief that diastolic heart failure is more benign than systolic heart failure, but in reality, that is not the case. They have similar prognosis when compared in general. However, patients with advanced systolic heart failure have a worse prognosis than those with diastolic heart failure. The complicating aspect is that there are no many proven therapies that work for diastolic heart failure, other than low sodium diet, diuretics, exercise, proper eating, and lifestyle modification. To provide a more precise diagnosis, it would be essential to understand how is your exercise tolerance, however that can be challenging with your multiple sclerosis. I hope this information helps. I do not want you to feel discouraged but instead focus on lifestyle modification. Eating well, stress reduction (mindfulness or mediation can help) and practice physical activity. Hypertension, and obesity. Possibly an exercise stress test to objectively assess your exercise capacity, sleep study, and probably a Holter or event monitor (to assess for arrhythmias or atrial fibrillation).