###Human: Can hormonal acne indicate sensitivity to testosterone? ###Assistant: Hello. I just read your query and from what you have mentioned it appears that you have acne. Usually, it is not recommended to do estradiol test for acne. However, you can visit your gynecologist for ruling out polycystic ovarian syndrome because that can give rise to acne given the history you have mentioned. If your PCOS is controlled well by a gynecologist, then no need to take any anti-androgen drugs like Spironolactone. It is an off label prescription for acne anyways. Yes, a dermatologist will also be beneficial once your gynecologist takes care of issues as well for your hair fall and acne.