###Human: I am severely anemic. Kindly help. ###Assistant: Hi. As you are on iron and vitamin B12 shots, I would assume that it could be nutritional. It is obvious that no absorption from the gut and also IBS will complicate it. Enlarged spleen could be due to increased destruction in spleen or production of cells in the spleen to improve anemia (extramedullary hematopoiesis).  I would like to know the following details: