###Human: What is the treatment for thalassemia major? ###Assistant: Hi. At present there is no way to reduce the spleen size. Diet for thalassemia major patient should include plenty of fruits and vegetables and protein rich diet. Taking vitamin C supplements will help to increase the immunity of the body. Bone marrow transplantation is a curative treatment for thalassemia major (symptoms of severe anemia from childhood). Bone marrow transplantation can be done if you do not have any long-term complication of thalassemia major. Adult thalassemia patients are higher risk patients for transplant-related toxicity due to an advanced phase of disease and have a cure rate of 60 to 70% with current treatment protocol. There is 90% long-term survival rate in patients with favorable characteristics such as young age, HLA (human leukocyte antigen) match and no organ dysfunction. I would suggest you to consult a hematologist who can guide you better.