###Human: What is the treatment for eye infection due to pythium? ###Assistant: Hi. In case the organism is pythium as you have said, it has been found that it does not respond to available antifungals. Previously patients have been managed by corneal transplant to remove the infected organ so that it does not affect inner parts of the eye. Your decision will depend on how well the infection is responding to the treatment being tried. If it is increasing despite all the medications, a corneal transplant may be the only way forward. Better to keep serial photographs of the eye for comparison and easy decision making.