###Human: I am taking Levofloxacin for prostatitis. Will this cause any permanent side-effect? ###Assistant: Hello. You are suffering from chronic prostatitis. It is very difficult to treat. Ideally, prostatic massage and EPS or semen culture must be done. But, if you have an improvement with Levofloxacin, then you can take it. The side effects are if you take it for a very long duration in years. For an acute episode as now take Levofloxacin. Then later, you can shift to oral low dose Nitrofurantoin 100 mg daily for three months. I would also like to add Doxycycline (with Levofloxacin) 100 mg bd for 14 days for an atypical organism. Fosfomycin is reserved in case you have resistance with other drugs. So do not use now.