###Human: Are Hashimoto’s, and ankylosing spondylitis the reason for severe hair loss? ###Assistant: Hello. Hair loss in females can be due to many causes, most common being 1. Telogen effluvium stress-induced, due to illness, a diet with low protein intake, surgery, post-pregnancy, and mental stress. 2. Female pattern alopecia is genetic and hormone-mediated, runs in the family. 3. Diffuse alopecia areata is autoimmune condition usually associated with other autoimmune disorders like diabetes, thyroid disorders, and ulcerative colitis. 4. Drugs such as Isotretinoin, and Chemotherapy drugs induce hair fall. 5. Lupus, scarring alopecia. With your description, it seems like diffuse hair loss, but I cannot confirm unless I see the pictures. In your situation, I feel it is autoimmune condition most probably diffuse alopecia areata, because you have been diagnosed with Hashimoto's and ankylosing spondylitis. I do not know if you have taken an injection of corticosteroids (Triamcinolone) for the scalp. This is very helpful in an autoimmune condition. I am considering the most probable cause, and it could even be female pattern alopecia. Do you have a family history of baldness, history of surgery, illness, stressful events before you noticed hair loss? Please send the pictures of the scalp.