###Human: What causes pain in penis during erection? ###Assistant: Hi. I can understand your concern for your symptoms. Pain during erection can be due to: 1. Infection - common cause is urinary tract infection, other sexually transmitted infection. 2. Balanitis - inflammation of gland penis, tip of your penis can be due to allergy of infection. 3. Prostatitis - inflammation of prostate gland due to infection or injury or inflammation. 4. Urethritis - inflammation or infection of urethra. 5. Renal calculi  can cause painful erection. 6. Peyronie's disease - scar tissue inside the penis causing painful erection. 7. Neuropathy due to diabetes. Kindly share more details regarding above information and we can work on your treatment.