###Human: Can stress, weight loss or dehydration cause an increase in alkaline phosphatase level? ###Assistant: Hello. Since this question was posted under diabetology, I am wondering if you have any endocrine issues. The question asked here is about gastroenterology. The liver tests would be concerning for a liver process like gallstone if the enzymes were not coming back down or if you had pain in your right abdomen. Any fever? Dehydration can sometimes cause the numbers to be slightly up. It is important to have a follow up with your GP. You can also run the query through a gastroenterologist on icliniq.