###Human: Can osteoarthritis cause pain in knee? ###Assistant: Hello. Your X-rays are normal for age (attachment removed to protect patient identity). What you describe is patellofemoral compression syndrome and weight gain, wrong exercises, jogging on an incline, poor shoe wear, open chain exercise like squats, knee rolls have a role to play. Physiotherapy to do like closed chain exercises, leg presses with knee not bending more than 30 degrees, patellar taping, core strengthening exercises, gluteal clam shells, hamstring stretches, VMO (vastus medialis) exercise, etc. Take NSAID like Aceclofenac but I see no role of Glucosamine combination tablets. The process of relief takes a long time so do not get frustrated and believe me this is a curable condition but effort has to be yours.