One major drawback is that investing heavily in programming for one particular area of the health sector often means that funding for other areas suffers and human resources will flock towards working in that area that has more resources (the effect of international funding to HIV/AIDS and its effect on the family planning sector is one example).  In addition, running multiple parallel programs for one area results in duplication of services that are also uncoordinated between programs.  This leads to an increase in forms and paperwork for supplies and funding.