APR_HepG2_MicrotubuleCSK_24hr, is one of 10 assay component(s) measured or calculated from the APR_HepG2_24hr assay. It is designed to make measurements of protein conformation, a form of conformation reporter, as detected with fluorescence intensity signals by HCS Fluorescent Imaging technology.Data from the assay component APR_HepG2_MicrotubuleCSK_24hr was analyzed into 2 assay endpoints. 
This assay endpoint, APR_HepG2_MicrotubuleCSK_24h_dn, was analyzed in the negative fitting direction relative to DMSO as the negative control and baseline of activity. 
Using a type of conformation reporter, measures of protein for loss-of-signal activity can be used to understand the signaling at the cellular-level. 
Furthermore, this assay endpoint can be referred to as a primary readout, because this assay has produced multiple assay endpoints where this one serves a signaling function. 
To generalize the intended target to other relatable targets, this assay endpoint is annotated to the "cell morphology" intended target family, where the subfamily is "cell conformation". Is this molecule effective to this assay?